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American Journal of Perinatology

Alexander M Friedman, Cande V Ananth, Jessica A Lavery, Adiel A Fleischer, Cynthia Chazotte, Mary E D'Alton
OBJECTIVE:  To determine whether a state-level initiative to reduce obstetric venous thromboembolism (VTE) risk affected outcomes and process measures. METHODS:  In 2013, the Safe Motherhood Initiative (SMI) developed a VTE safety bundle to reduce obstetric VTE risk. A total of 117 of 124 hospitals providing obstetrical services in New York participated in SMI. Data evaluating thromboembolism events (deep vein thrombosis and pulmonary embolism) and thromboprophylaxis process measures were collected from March through November 2015...
September 13, 2018: American Journal of Perinatology
Janine S Rhoades, Victoria G Wesevich, Methodius G Tuuli, George A Macones, Alison G Cahill
OBJECTIVE:  To evaluate the implementation of an institutional protocol for universal delayed umbilical cord clamping (DCC) at term on maternal, neonatal, and umbilical cord blood gas outcomes. STUDY DESIGN:  This is a retrospective cohort study of singleton term gestations from April through July 2017. On June 1, 2017, a protocol was implemented for DCC in all deliveries. Outcomes were compared between patients delivered prior to and those delivered after implementation...
September 12, 2018: American Journal of Perinatology
John F Mission, Janet Catov, Tiffany Deihl, Maisa Feghali, Christina Scifres
OBJECTIVE:  Antibiotics are commonly used in pregnancy. Prior studies have indicated that antibiotic use in pregnancy may affect birth weight, whereas data in nonpregnant individuals suggest that antibiotic exposure may increase diabetes risk. We evaluated the impact of antibiotic prescriptions during pregnancy on the prevalence of small for gestational age (SGA) and large for gestational age (LGA) birth weight and gestational diabetes mellitus (GDM). STUDY DESIGN:  This retrospective cohort study of 12,551 women who delivered at a large academic medical center between 2012 and 2014 assessed the number and type of antibiotic prescriptions prior to GDM testing using the electronic medical record...
September 12, 2018: American Journal of Perinatology
Tatiana Z A L Sampaio, Margo Wilson, Cheryl Aubertin, Stephanie Redpath
INTRODUCTION:  In Canada, more than 4,000 critically ill newborns per year require transfer. Transports are initially managed based on information conveyed by referral practitioners. OBJECTIVES:  To identify the frequency of diagnostic discordance between the referring facility, transport team, and tertiary care center in our outborn neonatal population and to verify the association between discordance events (DEs), prolonged transport stabilization times, and potential risk factors to further inform and facilitate the development of future outreach education initiatives...
September 12, 2018: American Journal of Perinatology
William F Rayburn, Jose M Perez, Imam M Xierali
OBJECTIVE:  To examine patterns in relocation of maternal-fetal medicine (MFM) specialists during the recent 10 years. STUDY DESIGN:  This descriptive study analyzed the migration of MFM specialists between 2006 and 2016 based on county locations. Year-to-year comparisons of physicians in active clinical practice were performed. Demographic and county characteristics were gathered from three data resources. A multivariable logistic regression model was used to identify factors associated with relocation...
September 12, 2018: American Journal of Perinatology
Sandra Fucile, Sarah Phillips, Kelly Bishop, Meagan Jackson, Taylor Yuzdepski, Kimberly Dow
OBJECTIVE:  Preterm infants are at risk of encountering oral feeding difficulties which impede on the transition to independent oral feeds. The objective of this study was to identify a pivotal period where regressions are most likely to occur during their oral feeding progression. STUDY DESIGN:  This is a retrospective study on 101 infants born <35 weeks' gestation. The sample was separated into two groups, infants who experienced a regression during their oral feeding progression and those who did not...
September 12, 2018: American Journal of Perinatology
Suzan L Carmichael, Yair J Blumenfeld, Jonathan A Mayo, Jochen Profit, Gary M Shaw, Susan R Hintz, David K Stevenson
OBJECTIVE:  We compared the prevalence of and risk factors for stillbirth and live birth at periviable gestational age (20-25 weeks). STUDY DESIGN:  This is a cohort study of 2.5 million singleton births in California from 2007 to 2011. We estimated racial-ethnic prevalence ratios and used multivariable logistic regression for risk factor comparisons. RESULTS:  In this study, 42% of deliveries at 20 to 25 weeks' gestation were stillbirths, and 22% were live births who died within 24 hours...
September 12, 2018: American Journal of Perinatology
Marina Ayrapetyan, Kiran Talekar, Kathleen Schwabenbauer, David Carola, Kolawole Solarin, Dorothy McElwee, Susan Adeniyi-Jones, Jay Greenspan, Zubair H Aghai
OBJECTIVE:  To determine the short-term outcomes (abnormal brain magnetic resonance imaging [MRI]/death) in infants born with a 10-minute Apgar score of 0 who received therapeutic hypothermia and compare them with infants with higher scores. STUDY DESIGN:  This is a retrospective review of 293 neonates (gestational age ≥ 35 weeks) born between November 2006 and October 2015 admitted with hypoxic-ischemic encephalopathy who received therapeutic hypothermia...
September 12, 2018: American Journal of Perinatology
(no author information available yet)
No abstract text is available yet for this article.
September 11, 2018: American Journal of Perinatology
Rachel Shulman, Teresa N Sparks, Kristen Gosnell, Cinthia Blat, Mary E Norton, Hanmin Lee, Juan Gonzalez-Velez, Ruth B Goldstein
OBJECTIVE:  To examine the relationship between cardiomediastinal shift angle (CMSA) and adverse perinatal outcomes and hydrops in cases of congenital pulmonary airway malformation (CPAM). STUDY DESIGN:  This retrospective study evaluated CPAM cases referred to our institution from 2008 to 2015. The primary outcome was a composite score for adverse perinatal outcome. CMSA was measured for each case and evaluated for its association with the primary outcome. The prediction accuracy of CMSA for adverse perinatal outcome was assessed using receiver operator characteristic (ROC) curves...
September 10, 2018: American Journal of Perinatology
Sandra R Herrera, Kathleen L Vincent, Aaron Poole, Gayle Olson, Igor Patrikeev, Jamal Saada, Phyllis Gamble, Massoud Motamedi, George R Saade, Alison M Stuebe, Egle Bytautiene Prewit
OBJECTIVE:  Epidemiological studies suggest that lactation is associated with long-term maternal health benefits. To avoid confounders in human studies, we used a previously characterized murine model to investigate the long-term effect of lactation on both cardiovascular function and adiposity. STUDY DESIGN:  After the delivery of the pups, CD-1 female mice were randomly divided into two groups: lactated and nonlactated (NL). Before pregnancy and at 9 months postdelivery, blood pressure was measured using a tail cuff, visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were assessed by computed tomography (CT), echocardiography was performed using microultrasound, and cholesterol panels and fasting blood glucose were measured...
September 7, 2018: American Journal of Perinatology
Joshua I Rosenbloom, Jonathan S Hirshberg, Molly J Stout, Alison G Cahill, George A Macones, Methodius G Tuuli
OBJECTIVE:  To investigate the association between the intraoperative diagnosis of placenta accreta at the time of cesarean hysterectomy and pathological diagnosis. STUDY DESIGN:  This is a retrospective cohort study of all patients undergoing cesarean hysterectomy for suspected placenta accreta from 2000 to 2016 at Barnes-Jewish Hospital. The primary outcome was the presence of invasive placentation on the pathology report. We estimated predictive characteristics of clinical diagnosis of placenta accreta using pathological diagnosis as the correct diagnosis...
September 7, 2018: American Journal of Perinatology
Maya Tabet, Louise H Flick, Hong Xian, Jen Jen Chang
BACKGROUND:  There has been a call for customized rather than population-based birthweight standards that would classify smallness based on an infant's own growth potential. Thus, this study aimed to examine the association between the difference in sibling birthweight and the likelihood of neonatal death among second births in a U.S. POPULATION: <AbstractText Label="METHODS" NlmCategory="METHODS"> This was a population-based cohort study including 179,300 women who delivered their first two nonanomalous singleton live births in Missouri (1989-2005)...
September 7, 2018: American Journal of Perinatology
Megan M Marvin, Fumiyuki C Gardner, Kristin M Sarsfield, R Alberto Travagli, Kim K Doheny
OBJECTIVE:  An estimation of the individual's ability to cope to environmental adversity, that is, stress resiliency, can be extrapolated by measuring cardiac vagal tone, that is, high-frequency heart rate variability (HF-HRV); indeed, higher HF-HRV is associated with health and developmental advantages for preterm neonates. Previous studies show skin-to-skin contact (SSC) improves stress resiliency; however, linkages between SSC and HF-HRV on outcomes have not been assessed. We aimed to test the hypothesis that increased SSC frequency would enhance HF-HRV, reduce neonatal morbidity, and improve developmental outcomes...
September 7, 2018: American Journal of Perinatology
Colin Korlesky, Pamela J Kling, Daphne Q D Pham, Albina A Ovasapyan, Cheryl E G Leyns, Morgan B Weber, Christopher L Coe
OBJECTIVE:  Obesity during pregnancy impedes fetal iron endowment. In adults, both iron depletion and hypoxia stimulate erythropoietin (Epo) production, while hepcidin, the primary iron regulator, is inhibited by Epo and stimulated by obesity. To understand this relationship in fetuses, we investigated obesity, inflammation, and fetal iron status on fetal Epo and hepcidin levels. STUDY DESIGN:  Epo, hepcidin, C-reactive protein (CRP), and ferritin levels were measured in 201 newborns of 35 to 40 weeks' gestation with historical risk factors for a low fetal iron endowment, including half with maternal obesity...
September 7, 2018: American Journal of Perinatology
Whitney Bender, Adi Hirshberg, Lisa D Levine
OBJECTIVE:  To examine the change in body mass index (BMI) categories between pregnancies and its effect on adverse pregnancy outcomes. STUDY DESIGN:  We performed a retrospective cohort study of women with two consecutive deliveries from 2005 to 2010. Analysis was limited to women with BMI recorded at <24 weeks for both pregnancies. Standard BMI categories were used. Adverse pregnancy outcomes included preterm birth at <37 weeks, intrauterine growth restriction (IUGR), pregnancy-related hypertension, and gestational diabetes mellitus (GDM)...
September 7, 2018: American Journal of Perinatology
(no author information available yet)
No abstract text is available yet for this article.
September 6, 2018: American Journal of Perinatology
Ashish Gupta, Martin Keszler
OBJECTIVE:  To provide current data on ventilation practices and use of volume-targeted ventilation (VTV) in neonatal intensive care units of the United States and Canada, to identify the perceived barriers to the implementation of VTV, and to assess the knowledge base of appropriate initial tidal volume ( VT ) settings for different hypothetical clinical scenarios. STUDY DESIGN:  This was a cross-sectional online survey of individual neonatologists practicing in the United States and Canada...
September 6, 2018: American Journal of Perinatology
Mary Catherine Tolcher, Megan D Whitham, Sherif A El-Nashar, Steven L Clark
OBJECTIVE:  To compare chlorhexidine-alcohol with povidone-iodine solutions for skin antisepsis prior to cesarean delivery for the prevention of surgical site infection. STUDY DESIGN:  Electronic databases MEDLINE, Embase, Scopus, and were searched from inception to August 2017. Eligible studies included randomized controlled trials comparing chlorhexidine-alcohol with povidone-iodine skin preparation solutions for women undergoing cesarean delivery...
September 5, 2018: American Journal of Perinatology
Clodagh Mullen, Ashley N Battarbee, Linda M Ernst, Alan M Peaceman
OBJECTIVE:  To assess the risk factors, adverse obstetrical outcomes, and recurrence risk associated with pathologically diagnosed occult placenta accreta. METHODS:  This was a retrospective observational study of clinically adherent placentas requiring manual extraction that underwent pathological examination. Cases were defined as those with histological evidence of placenta accreta, and controls were defined as those without accreta. All subsequent pregnancies were evaluated to determine the recurrence risk of occult accreta in future pregnancies...
September 5, 2018: American Journal of Perinatology
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