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American Journal of Perinatology

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https://www.readbyqxmd.com/read/29458216/institution-of-a-comprehensive-postpartum-hemorrhage-bundle-at-a-large-academic-center-does-not-immediately-reduce-maternal-morbidity
#1
Rebecca Feldman Hamm, Eileen Wang, Kathleen O'Rourke, April Romanos, Sindhu K Srinivas
OBJECTIVE: Obstetric hemorrhage is a leading cause of morbidity and mortality. We sought to assess whether institution of a postpartum hemorrhage (PPH) bundle could improve maternal morbidity in our population. STUDY DESIGN: Preintervention data (PRE) was collected on all deliveries at Hospital of the University of Pennsylvania between October 15, 2013 and December 15, 2013. A two-pronged, multidisciplinary educational and procedural intervention related to PPH was instituted from March 2015 to June 2015...
February 19, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29458215/factors-associated-with-placental-vascularization-measured-by-3d-power-doppler-ultrasonographic-sphere-biopsy-between-11-and-14-weeks-of-gestation
#2
Suzanne Demers, Amelie Boutin, Regina Dembickaja, Mercedes Campanero, Kypros Nicolaides
OBJECTIVE: Preeclampsia is associated with placental vascularization disorders. Ultrasonographic sphere biopsy (USSB) of the placenta can estimate the vascularization of the placenta and potentially the risk of preeclampsia. We aimed to explore the factors related to placental vascularization measured with USSB in the first trimester. STUDY DESIGN: A prospective cohort was conducted in women recruited at 11 to 14 weeks. Three-dimensional acquisition of the placenta with power Doppler was undertaken along with crown-rump length (CRL)...
February 19, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29454303/smfm-2018-meeting-highlights-friday-podcast
#3
(no author information available yet)
No abstract text is available yet for this article.
February 17, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29452428/illness-severity-predicts-death-and-brain-injury-in-asphyxiated-newborns-treated-with-hypothermia
#4
Hui Wang, Marc Beltempo, Emmanouil Rampakakis, Priscille-Nice Sanon, Stephanie Barbosa Vargas, Julie Maluorni, Christine Saint-Martin, Pia Wintermark
OBJECTIVE: To determine if illness severity during the first days of life predicts adverse outcome in asphyxiated newborns treated with hypothermia. STUDY DESIGN: We conducted a retrospective cohort study of asphyxiated newborns treated with hypothermia. Illness severity was calculated daily during the first 4 days of life using the Score for Neonatal Acute Physiology II (SNAP-II score). Adverse outcome (death and/or brain injury) was recorded. Differences in SNAP-II scores between the newborns with and without adverse outcome were assessed...
February 16, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29452427/effect-of-routine-screening-head-ultrasounds-on-clinical-interventions-for-premature-infants
#5
Andrew Z Heling, Matthew M Laughon, Wayne A Price
OBJECTIVE: This article assesses whether routine, screening head ultrasound (HUS) studies performed at 7 to 14 postnatal days for premature infants are followed by clinical interventions. STUDY DESIGN: This retrospective cohort study included all inborn infants delivered at < 30 weeks' gestational age (GA) between January 1, 2012 and December 31, 2015 at a single center who had a routine, screening HUS performed between 7 and 14 postnatal days ( n = 303). We defined "clinical intervention" as a 7 to 14 postnatal day HUS that was followed by neurosurgical intervention prior to a 36- to 40-week postmenstrual age (PMA) HUS or elective withdrawal of critical care within 30 days of a positive HUS finding...
February 16, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29444534/smfm-2018-meeting-highlights-thursday-podcast
#6
(no author information available yet)
No abstract text is available yet for this article.
February 14, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29444533/relationship-between-blood-glucose-fluctuation-and-brain-damage-in-the-hypoglycemia-neonates
#7
Yuan Lv, Ling-Ling Zhu, Gui-Hua Shu
OBJECTIVE: To investigate the relationship between blood glucose fluctuation and brain damage in the hypoglycemia neonates. STUDY DESIGN: A retrospective study including all neonates hospitalized due to hypoglycemia from September 2013 to August 2016 was performed. All the 58 hypoglycemia infants were divided into two groups-the brain-damaged group and the nonbrain-damaged group, according to head magnetic resonance imaging and/or amplitude-integrated electroencephalogram...
February 14, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29439282/programmatic-and-administrative-barriers-to-high-risk-infant-follow-up-care
#8
Brian G Tang, Henry C Lee, Erika E Gray, Jeffrey B Gould, Susan R Hintz
OBJECTIVE:  This article characterizes programmatic features of a population-based network of high-risk infant follow-up programs and identifies potential challenges associated with attendance from the providers' perspective. STUDY DESIGN:  A web-based survey of high-risk infant follow-up program directors, coordinators, and providers of a statewide high-risk infant follow-up system. Frequencies and percentages were used to describe the survey responses. RESULTS:  Of the 68 high-risk infant follow-up programs in California, 56 (82%) responded to the survey...
February 13, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29433145/effect-of-cord-blood-magnesium-level-at-birth-on-non-neurologic-neonatal-outcomes
#9
James M Edwards, Laura E Edwards, Geeta K Swamy, Chad A Grotegut
OBJECTIVE: We examined the effects of magnesium sulfate on non-neurologic neonatal outcomes with respect to cord blood magnesium level. STUDY DESIGN: We conducted a secondary analysis of the Maternal-Fetal Medicine Units Beneficial Effects of Antenatal Magnesium (MFMU BEAM) trial comparing the upper and lower quintiles of cord blood magnesium level. Outcomes included cerebral palsy (CP), necrotizing enterocolitis (NEC), retinopathy of prematurity (ROP), bronchopulmonary dysplasia (BPD), and assessments of mental and motor disability...
February 12, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29433144/smith-lemli-opitz-mutations-in-unexplained-stillbirths
#10
Karen J Gibbins, Uma M Reddy, George R Saade, Robert L Goldenberg, Donald J Dudley, Corette B Parker, Vanessa Thorsten, Halit Pinar, Radek Bukowski, Carol J Hogue, Robert M Silver
OBJECTIVE:  Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive syndrome caused by a defect in cholesterol biosynthesis with mutations in 7-dehydrocholesterol reductase (DHCR7). A total of 3% of Caucasians carry DHCR7 mutations, theoretically resulting in a homozygote frequency of 1/4000. However, SLOS occurs in only 1/20,000 to 60,000 live births. Our objective was to assess DHCR7 mutations in unexplained stillbirths. STUDY DESIGN:  Prospective, multicenter, population-based case-control study of all stillbirths and a representative sample of live births enrolled in five geographic areas...
February 12, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29421833/choice-of-trial-of-labor-after-cesarean-and-association-with-likelihood-of-success
#11
Leanna S Sudhof, Phinnara Has, Dwight J Rouse, Brenna L Hughes
OBJECTIVE: To investigate whether the predicted chance of success is associated with the choice to undergo trial of labor after cesarean (TOLAC). STUDY DESIGN: Retrospective cohort study of women with a single prior nonelective cesarean delivering a term singleton in 2012 at a tertiary care hospital. A vaginal birth after cesarean (VBAC) score (likelihood of success) was estimated for each patient. The primary outcome was percentage of women choosing TOLAC among women with favorable (> 70% likelihood) and unfavorable VBAC scores...
February 8, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29421832/heparin-induced-thrombocytopenia-during-obstetric-hospital-admissions
#12
Deepika Sagaram, Zainab Siddiq, Andrew B Eisenberger, Cande V Ananth, Jason D Wright, Mary E D'Alton, Alexander M Friedman
INTRODUCTION:  The rate of heparin-induced thrombocytopenia (HIT) on a population basis is unknown. The objective of this study was to characterize the risk for HIT during antepartum, delivery, and postpartum hospitalizations in the United States. MATERIALS AND METHODS: A large administrative database was used to determine the risk of HIT in hospitalized obstetric patients who received unfractionated heparin (UFH) or low molecular weight heparin (LMWH). Patients were presumed to have HIT if they were exposed to UFH or LMWH, received a diagnosis of HIT, and were administered a medication for the treatment of HIT including bivalirudin, argatroban, fondaparinux, or lepirudin...
February 8, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29421831/amplitude-integrated-eeg-and-cerebral-near-infrared-spectroscopy-in-cooled-asphyxiated-infants
#13
C K Niezen, A F Bos, D A Sival, L C Meiners, H J Ter Horst
OBJECTIVE:  To assess the predictive value of amplitude-integrated electroencephalography EEG (aEEG) and near-infrared spectroscopy (NIRS) during therapeutic hypothermia. PATIENTS AND METHODS:  We studied 39 cooled, asphyxiated infants. We assessed aEEG and calculated mean regional cerebral oxygen saturation (rcSO2) during and after treatment. At 30 months, we performed a neurological examination and administered the Bayley Scales of Infant and Toddler Development, 3rd edition...
February 8, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29390201/how-are-neonatology-fellows-trained-for-antenatal-periviability-counseling-podcast
#14
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29365330/is-uterocervical-angle-associated-with-gestational-latency-after-physical-exam-indicated-cerclage
#15
Kate Swanson, William A Grobman, Emily S Miller
OBJECTIVE:  Prediction of gestational latency after placement of physical exam indicated cerclage (PEIC) is limited. Uterocervical angle (UCA) has been associated with spontaneous preterm delivery in the general population. Our objective was to examine whether UCA is associated with gestational latency in women with PEIC. STUDY DESIGN:  This retrospective cohort included women with a singleton gestation who had PEIC placed at a single tertiary care center between January 2010 and September 2015...
January 24, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29365329/the-relationship-between-body-mass-index-in-pregnancy-and-adverse-maternal-perinatal-and-neonatal-outcomes-in-rural-india-and-pakistan
#16
Vanessa L Short, Stacie E Geller, Janet L Moore, Elizabeth M McClure, Shivaprasad S Goudar, Sangappa M Dhaded, Bhalachandra S Kodkany, Sarah Saleem, Farnaz Naqvi, Omrana Pasha, Robert L Goldenberg, Archana B Patel, Patricia L Hibberd, Ana L Garces, Marion Koso-Thomas, Menachem Miodovnik, Dennis D Wallace, Richard J Derman
OBJECTIVE:  The objective of this study was to describe the relationship between early pregnancy body mass index (BMI) and maternal, perinatal, and neonatal outcomes in rural India and Pakistan. STUDY DESIGN:  In a prospective, population-based pregnancy registry implemented in communities in Thatta, Pakistan and Nagpur and Belagavi, India, we obtained women's BMI prior to 12 weeks' gestation (categorized as underweight, normal, overweight, and obese following World Health Organization criteria)...
January 24, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29365328/outcomes-of-spontaneous-labor-in-women-undergoing-trial-of-labor-after-cesarean-as-compared-with-nulliparous-women-a-retrospective-cohort-study
#17
Sarah C Lassey, Julian N Robinson, Anjali J Kaimal, Sarah E Little
OBJECTIVE: The objective of this study was to compare spontaneous labor outcomes in women undergoing trial of labor after cesarean (TOLAC) and nulliparas to better counsel women. STUDY DESIGN: A 4-year retrospective cohort. We included women at term in spontaneous labor with vertex singletons and no more than one prior cesarean delivery. In planned secondary analysis, we focused on a subset of women with a prior cesarean and a predicted likelihood of a successful vaginal delivery of 70% or more based on the Maternal-Fetal Medicine Units-vaginal birth after cesarean (VBAC) calculator...
January 24, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29365327/histologic-funisitis-and-likelihood-of-intrauterine-inflammation-or-infection-a-case-control-study
#18
Morgen S Doty, Carolyn Salafia, Susan Shen-Schwarz, Edwin Guzman, George R Saade, Suneet P Chauhan
OBJECTIVE: The objective of this study was to ascertain the likelihood of isolated maternal fever and suspected intrauterine inflammation or infection or both (Triple I) among cases of histologic chorioamnionitis with funisitis (HCF) at term. STUDY DESIGN: In this case-control study, placental pathology records were reviewed to identify term singleton laboring patients with HCF. Controls (1:1) were matched for gestational age. RESULTS: During the 6-month period, there were 2,399 term deliveries of laboring women...
January 24, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29359280/smfm-2018-pregnancy-meeting-looking-ahead-to-the-scientific-program-podcast
#19
(no author information available yet)
No abstract text is available yet for this article.
January 22, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29341045/approach-to-infants-born-through-meconium-stained-amniotic-fluid-evolution-based-on-evidence
#20
Munmun Rawat, Sushma Nangia, Praveen Chandrasekharan, Satyan Lakshminrusimha
Meconium-stained amniotic fluid (MSAF) during delivery is a marker of fetal stress. Neonates born through MSAF often need resuscitation and are at risk of meconium aspiration syndrome (MAS), air leaks, hypoxic-ischemic encephalopathy, extracorporeal membrane oxygenation (ECMO), and death. The neonatal resuscitation approach to MSAF has evolved over the last three decades. Previously, nonvigorous neonates soon after delivery were suctioned under the vocal cords with direct visualization technique using a meconium aspirator...
January 16, 2018: American Journal of Perinatology
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