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American Journal of Perinatology

Soha S Patel, Nathanael C Koelper, Sindhu K Srinivas, Mary D Sammel, Lisa D Levine
OBJECTIVE:  We sought to compare adverse maternal outcomes between women with and without a uterine extension at the time of cesarean. STUDY DESIGN:  We conducted a retrospective cohort study of women with and without a uterine extension during a primary low transverse cesarean of a full-term singleton gestation. The primary outcomes were (1) estimated blood loss (EBL) and (2) composite maternal morbidity (defined as ≥ 1 of the following: blood transfusion, endometritis, or readmission)...
January 15, 2019: American Journal of Perinatology
Fionnuala Mone, Cecilia Mulcahy, Peter McParland, Paul Downey, Marie Culliton, Orla C Maguire, Eoghan E Mooney, Philip Clarke, David Fitzgerald, Elizabeth Tully, Fergal D Malone, Fionnuala M McAuliffe
OBJECTIVE:  To assess the effect of aspirin use in low-risk pregnancy on: (1) pregnancy-associated plasma protein-A (PAPP-A) and placental-like growth factor (PLGF); (2) urinary albumin-to-creatinine ratio (ACR) and blood pressure; (3) fetal growth parameters; and (4) placental histopathology. STUDY DESIGN:  This secondary analysis from the <u>T</u> rial of low-dose aspirin with an <u>E</u> arly <u>S</u> creening <u>T</u> est for preeclampsia and growth restriction randomized controlled trial was based on low-risk nulliparous women randomized at 11 weeks to (1) aspirin 75 mg; (2) no aspirin; and (3) aspirin based on the preeclampsia Fetal Medicine Foundation screening test...
January 15, 2019: American Journal of Perinatology
Courtney J Mitchell, Alan Tita, Sarah B Anderson, Daniel N Pasko, Lorie M Harper
OBJECTIVE:  We assessed the risk of small for gestational age and other outcomes in pregnancies complicated by chronic hypertension with blood pressure <140/90 mm Hg. STUDY DESIGN:  Retrospective cohort of singletons with hypertension at a single institution from 2000 to 2014. Mean systolic blood pressure and mean diastolic blood pressure were analyzed as continuous and dichotomous variables (<120/80 and 120-139/80-89 mm Hg). The primary outcome was small for gestational age...
January 15, 2019: American Journal of Perinatology
Alona Bin-Nun, Yair Kasirer, Francis Mimouni, Irina Schorrs, Daniel Fink, Cathy Hammerman
BACKGROUND AND OBJECTIVES:  Widened pulse pressure is generally associated with patent ductus arteriosus (PDA). Surprisingly, this is often not true for preterm infants during the first week of life when systolic and diastolic pressures are both reduced and pulse pressure may remain unchanged. METHODS:  This is a retrospective, observational review of individual blood pressure (BP) parameters preterm neonates <30 weeks' gestational age during the first week of life as correlated with ductal patency and severity...
January 15, 2019: American Journal of Perinatology
Ashley N Battarbee, Lynn M Yee
OBJECTIVE:  To measure the association of fast food density (FFD) and supermarket density (SD) with adverse neonatal outcomes in pregnancies with gestational diabetes mellitus (GDM). STUDY DESIGN:  This was a retrospective cohort study of women with GDM who delivered at a tertiary care center in a large metropolitan area (1/2010-2/2016). ZIP codes were used to link women with surrounding food environment. FFD and SD were calculated as the number of establishments per 100,000 residents for each ZIP code and classified into quartiles...
January 15, 2019: American Journal of Perinatology
Shilpi Chabra, Taylor Sawyer, Marya Strand
No abstract text is available yet for this article.
January 15, 2019: American Journal of Perinatology
(no author information available yet)
No abstract text is available yet for this article.
January 9, 2019: American Journal of Perinatology
Beata Łoniewska, Joanna Tousty, Barbara Michalczyk, Agnieszka Kordek, Agata Jankowska
OBJECTIVE:  The aim of the study is to evaluate the efficacy of noninvasive high-frequency ventilation (nHFV) in respiratory-deficient infants. STUDY DESIGN:  Retrospective analysis of 32 cases of nHFV in 30 term ( n  = 4) and preterm ( n  = 26) newborns using a noninvasive ventilation (NIV) device. nHFV avoided intubation of children performed with NIV and reintubation after long-term mechanical ventilation (MV). Patients were divided into three groups: Group 1: NIV from birth ( n  = 18, mean birth weight [BW]: 1,987 g, gestational age [GA]: 33...
January 8, 2019: American Journal of Perinatology
Gonzalo Zeballos Sarrato, Manuel Sánchez Luna, Susana Zeballos Sarrato, Alba Pérez Pérez, Isabel Pescador Chamorro, Jose María Bellón Cano
OBJECTIVE:  To investigate if the use of a visible respiratory function monitor (RFM) to use lower tidal volumes (Vts) during positive pressure ventilation (PPV) in the delivery room (DR) reduces the need of surfactant administration and invasive mechanical ventilation during the first 72 hours after birth of preterm infants <32 weeks' gestational age (GA). STUDY DESIGN:  Infants <32 weeks' GA ( n  = 106) requiring noninvasive PPV were monitored with a RFM at birth and randomized to visible ( n  = 54) or masked ( n  = 52) display on RFM...
January 8, 2019: American Journal of Perinatology
Anneloes M Plooij-Lusthusz, Nick van Vreeswijk, Margriet van Stuijvenberg, Arend F Bos, Elisabeth M W Kooi
OBJECTIVE:  Migration of umbilical venous catheters (UVCs) after initial correct position has been described. The aim of this study was to assess the incidence of malposition of the tip of the UVCs at 24 to 36 hours postinsertion. STUDY DESIGN:  Retrospective analysis of all neonates who had UVC placement in a 14-month period. The primary outcome was the rate of UVCs incorrectly positioned 24 to 36 hours after initial correct placement, defined as the UVC tip below or more than 5 mm above the level of the right diaphragm on a thoracoabdominal X-ray...
January 8, 2019: American Journal of Perinatology
Yair Kasirer, Alona Bin-Nun, Ateret Raveh, Irina Schorrs, Francis B Mimouni, Cathy Hammerman
BACKGROUND:  Intravenous lipid infusions improve both short- and long-term outcomes of premature neonates. However, prolonged infusion of lipids has been implicated in the development of parenteral nutrition-associated cholestasis (PNAC). We speculated that the multicomponent SMOFlipid would be hepatoprotective against PNAC. STUDY DESIGN:  This is a retrospective review comparing the incidence and severity of direct hyperbilirubinemia in preterm infants <1,500 g who were hospitalized for a minimum of 2 weeks during a 20-month period in which all preterm infants on total parenteral nutrition (TPN) received fat as Lipofundin with the following 20-month period in which all preterm infants on TPN received SMOFlipid...
January 8, 2019: American Journal of Perinatology
Weipeng Wang, Weihua Pan, Jie Chen, Wei Xie, Ming Liu, Jun Wang
OBJECTIVE:  Congenital diaphragmatic hernia (CDH) occurred in one of the twins is rarely seen. This study aims to describe the clinical features and outcomes of this special CDH. STUDY DESIGN:  The medical records of all CDH neonates treated in our institution between 2010 and 2016 were retrospectively reviewed. Data were analyzed using parametric and nonparametric tests, appropriately. Association between the twin pregnancy and outcomes was assessed. RESULTS:  Eighty-nine patients met the inclusion criteria...
January 4, 2019: American Journal of Perinatology
Marika Toscano, Dongmei Li, Timothy Dye, Courtney Olson-Chen
OBJECTIVE:  To compare rates of antepartum contraceptive counseling among women with preterm birth (PTB) and term birth. STUDY DESIGN:  This is a retrospective cohort study of patients with completed delivery records in New York from January 1, 2004, to December 31, 2014. Exposure was determined based on the timing of delivery. Exposed women delivered at <37 weeks, and nonexposed women delivered at ≥37 weeks. Primary outcome was patient response to questions regarding receipt of prenatal contraceptive counseling (PCC) by a health care provider...
January 4, 2019: American Journal of Perinatology
Rakesh Rao, Shamik Trivedi, Amy Distler, Steve Liao, Zachary Vesoulis, Christopher Smyser, Amit M Mathur
OBJECTIVE:  To review developmental outcomes of neonates with mild hypoxic-ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH). STUDY DESIGN:  Neonates ≥35 weeks' gestation with mild HIE/TH (TH group, n  = 30) were matched with healthy term-born infants (control group, n  = 30) and reviewed for the presence and severity of magnetic resonance imaging (MRI)-detected neurological injury. Neurodevelopmental outcomes were assessed using the Bayley Scales of Infant Development (BSID)...
January 4, 2019: American Journal of Perinatology
Dena Goffman, Cande V Ananth, Adiel Fleischer, Mary D'Alton, Jessica A Lavery, Richard Smiley, Kristin Zielinski, Cynthia Chazotte
OBJECTIVE:  To determine the effects of the Safe Motherhood Initiative's (SMI) obstetric hemorrhage bundle in New York State (NYS). METHODS:  In 2013, the SMI convened interprofessional workgroups on hemorrhage, venous thromboembolism, and hypertension tasked with developing evidence-based care bundles. Participating hospitals submitted data measured before, during, and after implementation of the hemorrhage bundle: maternal mortality, intensive care unit (ICU) admission, cardiovascular collapse, hysterectomy, and transfusion of ≥4 units of red blood cells (RBCs)...
January 4, 2019: American Journal of Perinatology
C Luke Dixon, Luis Monsivais, Petra Chamseddine, Gayle Olson, Luis D Pacheco, George R Saade, Maged M Costantine
OBJECTIVE:  To assess whether distraction using music and/or video games influences timing of analgesia request and improves pain outcomes in women undergoing labor induction. STUDY DESIGN:  A total of 219 pregnant women with singleton gestation undergoing labor induction with a Foley bulb (FB) at term were randomized to distraction with music and video games via iPod ( n  = 109) or no iPod ( n  = 110). The primary outcome was the time from FB placement to request for pain medication...
January 4, 2019: American Journal of Perinatology
Mohamed Abdelmawla, Deepak Louis, Michael Narvey, Yasser Elsayed
OBJECTIVE:  To test the hypothesis that a lung ultrasound severity score (LUSsc) can predict the development of chronic lung disease (CLD) in preterm neonates. STUDY DESIGN:  Preterm infants <30 weeks' gestational age were enrolled in this study. Lung ultrasound (LUS) was performed between 1 and 9 postnatal weeks. All ultrasound studies were done assessing three lung zones on each lung. Each zone was given a score between 0 and 3. A receiver operating characteristic curve was constructed to assess the ability of LUSsc to predict CLD...
January 4, 2019: American Journal of Perinatology
Pakaphan Kiatchoosakun, Junya Jirapradittha, Prapassara Sirikarn, Malinee Laopaiboon, Porjai Pattanittum, Woranart Chandrakachorn, Sakulrat Srirojana, Heather Jeffery, Sally Green, Pagakrong Lumbiganon
BACKGROUND:  Antibiotics are commonly prescribed in neonatal intensive care units (NICUs) for suspected sepsis because of the nonspecific clinical symptoms of sepsis. The overuse of antibiotic is associated with adverse outcomes. This study aimed to determine the rate of early-onset sepsis (EOS) and antibiotic use in neonates admitted to three NICUs in Northeast Thailand STUDY DESIGN:  This is a descriptive study using the data collected in the South East Asia-Using Research for Change in Hospital-acquired Infection in Neonates project...
December 31, 2018: American Journal of Perinatology
Amna Umer, Christa Lilly, Candice Hamilton, Lesley Cottrell, Timothy Lefeber, Thomas Hulsey, Collin John
OBJECTIVE:  The Birth Score Project (Project WATCH) began in the rural state of West Virginia (WV) in the United States in 1984. The project is intended to identify newborns with a greater risk of infant mortality. The primary objective of this study was to update the current Birth Score based on current literature and rigorous statistical methodology. STUDY DESIGN:  The study merged data from the Birth Score, Birth Certificate (birth years 2008-2013), and Infant Mortality Data ( N  = 121,640)...
December 28, 2018: American Journal of Perinatology
Clifton O Brock, Leslie A Moroz, Cynthia Gyamfi-Bannerman
OBJECTIVE:  To determine the risk of spontaneous preterm delivery (SPTD) associated with transvaginal cervical length (TVCL) in an unselected cohort. METHODS:  This is a retrospective study of serial TVCLs in unselected twin gestations. Receiver operator curves for SPTD were constructed from TVCLs at 18, 20, 22, and 24 weeks. Prediction thresholds were determined using a false discovery rate of 10%. The risk of SPTD was compared with previously published, prospective data from a meta-analysis...
December 28, 2018: American Journal of Perinatology
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