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Pharmacopsychiatry

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https://www.readbyqxmd.com/read/28351080/is-really-crocus-sativus-as-effective-as-citalopram-in-the-treatment-of-depression
#1
Konstantinos N Fountoulakis
No abstract text is available yet for this article.
March 28, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28351079/editorial-to-methamphetamine-crystal-meth-and-new-psychoactive-substances
#2
Ulrich S Zimmermann
No abstract text is available yet for this article.
March 28, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28346959/mirtazapine-induces-nightmares-in-depressed-patients
#3
Jens-Armin Buschkamp, Corinna Frohn, Georg Juckel
No abstract text is available yet for this article.
March 27, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28297728/evidence-based-guidelines-for-the-pharmacological-management-of-acute-methamphetamine-related-disorders-and-toxicity
#4
Norbert Wodarz, Anne Krampe-Scheidler, Michael Christ, Heribert Fleischmann, Winfried Looser, Katharina Schoett, Frank Vilsmeier, Lydia Bothe, Corinna Schaefer, Euphrosyne Gouzoulis-Mayfrank
No abstract text is available yet for this article.
March 15, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28293921/effects-of-intramuscular-midazolam-and-lorazepam-on-acute-agitation-in-non-elderly-subjects-a-systematic-review
#5
Sabrina Just Kousgaard, Rasmus W Licht, René Ernst Nielsen
Benzodiazepines are commonly used for the treatment of acute agitation in a psychiatric setting.We searched MEDLINE, EMBASE, PsycINFO, and the Cochrane Central Register of Controlled Trials (CENTRAL) for relevant publications. Randomized trials evaluating intramuscular (IM) midazolam or lorazepam given as monotherapy or as add-on treatment, with more than 10 patients aged 18-65 years, conducted in a psychiatric setting, and published between January 1, 1980, and February 3, 2016, were included. 16 studies from a search result of 5 516 studies were included...
March 14, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28278537/paliperidone-long-acting-plasma-level-monitoring-and-a-new-method-of-evaluation-of-clinical-stability
#6
Massimo Carlo Mauri, Silvia Paletta, Chiara Di Pace, Alessandra Reggiori, Chiara Rovera, Alessio Fiorentini, Carlo Alfredo Altamura
The second generation long-acting antipsychotics can be a pharmacologic strategy, both in the early phase of illness and in the case of low compliance. The aim of the study was to evaluate the clinical efficacy and tolerability of one monthly injection of paliperidone palmitate (PP1M), paliperidone plasma levels (PLs), and the clinical outcome. 21 outpatients, affected by Schizophrenia or Schizoaffective Disorder, were recruited. PP1M started with 150 mg on day 1 and 100 mg on day 8. Following patients were given a dosage ranging from 50 mg to 150 mg every 28 days...
March 9, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28178739/methamphetamine-consumption-during-pregnancy-effects-on-child-health
#7
Jürgen Dinger, Patricia Hinner, Jörg Reichert, Mario Rüdiger
Methamphetamine abuse during pregnancy represents an emerging health care problem. The consequences are not only of relevance to the pregnant women, but also their unborn child. It is associated with an increased risk of preeclampsia and hypertension, fetal demise, preterm delivery, and intrauterine growth restriction. The deleterious effects of prenatal methamphetamine exposure on the developing fetal brain may lead to long-term neuro-developmental and behavioral problems.Given the current evidence, abuse of methamphetamine during pregnancy must be of utmost concern to health care professionals and to policy-makers...
February 8, 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28208190/real-world-effectiveness-of-antipsychotics-for-the-treatment-of-negative-symptoms-in-patients-with-schizophrenia-with-predominantly-negative-symptoms
#8
MULTICENTER STUDY
Diego Novick, William Montgomery, Tamas Treuer, Maria Victoria Moneta, Josep Maria Haro
This study assessed the comparative effectiveness of antipsychotics in the treatment of patients with schizophrenia presenting with prominent negative symptoms and no-to-mild positive symptoms. Data were taken from a 3-year prospective, international, observational study (n=17 384). This post-hoc study focused on 3 712 patients who started antipsychotic monotherapy and had moderate-to-severe negative symptoms and no-to-mild positive symptoms (Clinical Global Impression-Severity Scale [GGI-SCH]). Patients were classified into 3 treatment cohorts: olanzapine, other atypicals and typicals...
March 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27978584/ppar-%C3%AE-agonists-for-the-treatment-of-major-depression-a-review
#9
REVIEW
R Colle, D de Larminat, S Rotenberg, F Hozer, P Hardy, C Verstuyft, B Fève, E Corruble
Introduction: Selective agonists of the nuclear transcription factor peroxisome proliferator-activated receptor-gamma (PPAR-γ) are used for the treatment of type 2 diabetes. We reviewed their efficacy and safety for the treatment of major depression and the association of their potential antidepressant effects with changes in biomarkers of metabolism and inflammation. Methods: From 8 studies, 4 open-label trials, and 4 randomized controlled trials (RCT) (3 vs. placebo and 1 vs. metformin), 448 patients with major depression were included, of which 209 patients received PPAR-γ agonists (pioglitazone or rosiglitazone) for 6-12 weeks, either alone or in add-on therapy to conventional treatments...
March 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27656915/effect-of-adjunctive-aripiprazole-on-sexual-dysfunction-in-schizophrenia-a-preliminary-open-label-study
#10
J Fujioi, K Iwamoto, M Banno, T Kikuchi, B Aleksic, N Ozaki
Introduction: Although adjunctive aripiprazole improves hyperprolactinemia, sufficient evidence for its effects on sexual dysfunction has not been obtained. We assessed the usefulness of adjunctive aripiprazole for schizophrenia with sexual dysfunction. Methods: 22 Japanese schizophrenia patients with antipsychotic-induced hyperprolactinemia and sexual dysfunction were enrolled, and 19 of them completed the study. Aripiprazole was administrated in a flexible titration schedule to participants according to the judgment of each doctor, and patients were followed for 24 weeks...
March 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27595298/comparison-of-saffron-versus-fluoxetine-in-treatment-of-mild-to-moderate-postpartum-depression-a-double-blind-randomized-clinical-trial
#11
RANDOMIZED CONTROLLED TRIAL
L Kashani, S Eslatmanesh, N Saedi, N Niroomand, M Ebrahimi, M Hosseinian, T Foroughifar, S Salimi, S Akhondzadeh
Introduction: Postpartum depression is a common mental health problem that is associated with maternal suffering. The aim of this double-blind clinical trial was to compare safety and efficacy of saffron and fluoxetine in treatment of mild to moderate postpartum depression. Methods: This was a 6-week, double-blind, randomized clinical trial. Subjects were women aged 18-45 years with mild to moderate postpartum depression who had Hamilton Depression Rating Scale (HDRS 17-item) score≤18. Eligible participants were randomized to receive either a capsule of saffron (15 mg capsule) or fluoxetine (20 mg capsule) twice daily for 6 weeks...
March 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27595297/the-relationship-between-psychotropic-drug-use-and-suicidal-behavior-in-japan-japanese-adverse-drug-event-report
#12
T Takeuchi, S Takenoshita, F Taka, M Nakao, K Nomura
Introduction: Very few studies have explored the adverse effect of psychotropic drugs worldwide. Methods: This study analyzed 1 813 suicide-related drug reports involving 553 patients collected from the Japanese National Adverse Drug Report Database between October 2001 and January 2012 to investigate psychotropic drugs associated with completed suicide vs. other suicide-related behaviors, including ideation and self-injury. The drugs investigated included antidepressants, antipsychotics, benzodiazepines, non-benzodiazepine hypnotic agents, noradrenergic and specific serotonergic antidepressants, selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, and other drugs...
March 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28122385/agnp-preis-f%C3%A3-r-forschung-in-der-psychopharmakologie
#13
(no author information available yet)
No abstract text is available yet for this article.
January 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/28118674/naming-for-psychotropic-drugs-dilemma-and-challenge
#14
Hiroyuki Uchida, Wolfgang Fleischhacker, Georg Juckel, Gerhard Gründer, Michael Bauer
No abstract text is available yet for this article.
January 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27574858/oxytocin-and-autism-spectrum-disorders-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#15
REVIEW
Yoon Phaik Ooi, Shih-Jen Weng, Joe Kossowsky, Heike Gerger, Min Sung
Aim: Oxytocin presents an exciting potential to target the core symptoms of autism spectrum disorder (ASD) pharmacologically in an easily administered, cost-effective form with possibly minimal adverse effects. But, there are still major gaps in this area of research. This paper reviewed randomized controlled trials (RCTs) examining the effects of oxytocin administration on social cognition and restricted, repetitive behaviors in individuals with an ASD. Method: Electronic literature searches were conducted from PsycINFO, PubMed, Web of Knowledge, and EMBASE for RCTs published through June 2015...
January 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27458743/electroconvulsive-therapy-induces-transient-sensitivity-for-a-serotonin-syndrome-a-case-report
#16
Michael Deuschle, Andreas Böhringer, Andreas Meyer-Lindenberg, Alexander Sartorius
Introduction: Serotonin syndrome is a potentially life-threatening condition with delirium, vegetative and neuromuscular symptoms as well as neural hyperexcitability. The main causes are combinations of serotonergic drugs, excessive dosages of serotonergic agents or the recreational use of certain drugs. Methods and Results: We report a case of a patient who started developing serotonin syndrome after a cumulative dose of only 900 mg lithium carbonate given in temporal association with electroconvulsive therapy (ECT)...
January 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27414740/use-of-paliperidone-palmitate-throughout-a-schizoaffective-disorder-patient-s-gestation-period
#17
F J Zamora Rodríguez, C Benítez Vega, M R Sánchez-Waisen Hernández, J A Guisado Macías, F J Vaz Leal
Introduction: Paliperidone palmitate treatment of schizophrenia or schizoaffective disorder is effective and well tolerated, but there is almost no data on its safety during pregnancy. Case report: An analysis is made of the safety and tolerability of paliperidone palmitate treatment throughout the gestation period in a 34-year-old patient diagnosed with schizoaffective disorder. Discussion: Paliperidone palmitate treatment throughout the gestation period was safe and well tolerated by both mother and foetus, there being no malformations or other perinatal complications in the newborn to date...
January 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27414739/-759c-t-polymorphism-of-the-htr2c-gene-is-associated-with-second-generation-antipsychotic-induced-weight-gain-in-female-patients-with-schizophrenia
#18
Federico Manuel Daray, Demián Rodante, Laura G Carosella, María Elena Silva, Melina Martínez, María V Fernández Busch, Diego F Faccone, Rodolfo P Rothlin, Paulo C Maffía
Introduction: The HTR2C gene is an important candidate in pharmacogenetic studies of antipsychotic-induced weight gain (AIWG). However, inconsistent results have been obtained. The present study investigated the association between -759C>T, functional polymorphism of the HTR2C receptor, and AIWG. Methods: A prospective cohort of 48 female inpatients with schizophrenia and related illness treated according to normal clinical practice with second generation antipsychotics (SGAs) risperidone, clozapine, quetiapine, and olanzapine were evaluated...
January 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27388714/neuroleptics-affect-kisspeptin-mrna-expression-in-the-male-rat-hypothalamus-and-hippocampus
#19
Artur Pałasz, Ewa Rojczyk, Aleksandra Suszka-Świtek, Ryszard Wiaderkiewicz
Introduction: Kisspeptin has a multidirectional neuroendocrinal activity. It is especially considered to be a central regulator of reproductive function. Numerous data proved that neuroleptic administration may affect the peptidergic signaling in the various brain structures. However, there is no information concerning the relationship between treatment with neuroleptics and brain kisspeptin mRNA expression. Methods: We assessed the kisspeptin mRNA level in the hypothalamus and hippocampus of rats shortly and chronically (28 days) treated with haloperidol, chlorpromazine, and olanzapine using a quantitative Real-Time PCR method...
January 2017: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27299475/comparing-efficacy-and-side-effects-of-memantine-vs-risperidone-in-the-treatment-of-autistic-disorder
#20
Nikvarz Nikvarz, Javad Alaghband-Rad, Mehdi Tehrani-Doost, Abbas Alimadadi, Padideh Ghaeli
Introduction: This study was aimed to compare the efficacy and side effects of memantine, an antagonist of the NMDA receptor of glutamate, with risperidone given the fact that glutamate has been noted for its possible effects in the pathogenesis of autism. Risperidone, an atypical antipsychotic, has been approved by FDA for the management of irritability associated with autism. Methods: 30 children, aged 4-17 years, entered an 8-week, randomized trial. Patients were randomly assigned to receive either risperidone or memantine...
January 2017: Pharmacopsychiatry
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