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International Angiology: a Journal of the International Union of Angiology

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https://www.readbyqxmd.com/read/30001612/internal-iliac-artery-preservation-strategies-in-the-endovascular-treatment-of-aortoiliac-aneurysms
#1
Carolina Robalo, Joel Sousa, Armando Mansilha
INTRODUCTION: Common iliac aneurysms are present in up to 40% of abdominal aortic aneurysms and frequently impair distal landing zones for endovascular aneurysm repair. Several techniques have been developed in order to overcome these issues, with different applications and conflicting results. Although long-term outcomes of hypogastric exclusion are favorable, the risks of pelvic ischemia and morbidity rates are high. We aim to review current hypogastric preservation strategies used in the endovascular treatment of aortoiliac aneurysms...
July 9, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29963797/midterm-results-with-drug-coated-balloons-for-sfa-lesions-in-patients-with-cli-comparison-with-conventional-bypass-surgery
#2
Onur S Goksel, Eren Karpuzoğlu, Halim Işsever, Bayer Çinar
BACKGROUND: Endovascular treatment of symptomatic peripheral artery disease has gained widespread acceptance. The efficacy and safety of drug coated balloon angioplasty in the setting of critical limb ischemia in comparison to conventional surgery has not been demonstrated. We have compared our results with DCB angioplasty to conventional bypass surgery in patients with critical limb ischemia. METHODS: A total of 187 patients with CLI treated over a 6-year period between 2006 and 2012 by a single operative team constituted the study population...
June 29, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29952159/improvement-of-arterial-wall-phenotype-in-subjects-at-moderate-cardiovascular-risk-induced-by-very-low-dose-fluvastatin-valsartan-combination-a-pilot-study
#3
Martina Turk Veselič, Neža Žorž, Barbara Eržen, Petra Škerl, Srdjan Novaković, Miodrag Janić, Mišo Šabovič
BACKGROUND: The largest population that suffers from cardiovascular events are subjects at moderate cardiovascular risk. However, no effective and safe preventive treatment is available for this population. We investigated whether their arterial wall phenotype could be turned to a lower risk direction by low-dose fluvastatin/valsartan combination (low-flu/val). METHODS: Twenty males at moderate cardiovascular risk (as classified by SCORE) were blindly randomised into the intervention group (n=10, low-flu/val: 10 mg/20mg) or control group (n=10, placebo)...
June 27, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29792018/predictive-factors-of-a-poor-outcome-following-revascularization-for-critical-limb-ischemia-implications-for-practice
#4
Mireia Martínez, Claudia Sosa, Alina Velescu, Carme Llort, Roberto Elosua, Albert Clarà
BACKGROUND/OBJECTIVE: Advancements in open and endovascular techniques have brought a widespread indication of revascularization in the majority of patients with critical limb ischemia (CLI). However, some cases still have a dismal short-term outcome. Identifying preoperative variables that characterize these patients could be important to prevent futile decisions. The aim of this study was to define predictive risk factors of mortality and/or major amputation after revascularization for CLI...
May 23, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29936722/epidemiology-of-peripheral-artery-disease-in-europe-vas-educational-paper
#5
Dan-Mircea Olinic, Mihail Spinu, Maria Olinic, Calin Homorodean, Dan-Alexandru Tataru, Aaron Liew, Gerit-Holger Schernthaner, Agata Stanek, Gerry Fowkes, Mariella Catalano
This paper reviews the current epidemiological data on peripheral artery disease (PAD) in Europe. Cardiovascular disease (CVD) burden is presented and PAD prevalence is discussed, as compared to coronary (CAD) and cerebrovascular (CeVD) diseases, in European Union (EU) countries and European continent countries. The article reviews PAD clinical manifestations, PAD diagnosis, risk factors for PAD incidence and progression, PAD prognosis and financial implications. CVD mortality is higher in women than in men and in European continent countries, as compared to EU countries...
August 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29936721/heparin-promotes-recanalization-of-venous-thrombotic-occlusions
#6
Pavel Poredos, Peter Poredos, Mateja K Jezovnik
Thrombosis is a consequence of disbalance between the procoagulant and fibrinolytic activity of blood and is frequently associated with chronic sequelae, which are the consequence of chronic occlusion of affected veins. Treatment of venous thrombosis should not be oriented in the prevention of thrombus progression and associated thromboembolic events, but also in stimulation of thrombolysis and recanalization of occluded veins, which are one of the most important preventive mechanisms of late sequelae, including post-thrombotic syndrome...
August 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29745618/medical-management-of-stable-peripheral-artery-disease-the-compass-trial-perspectives-from-a-vascular-standpoint
#7
Eduardo Ramacciotti, Valter Castelli, Jeanine Walenga, Jawed Fareed
The late-breaking presentation of the COMPASS (Cardiovascular Outcomes for People Using Anticoagulation Strategies) trial at the European Society of Cardiology Congress in 2017 with a simultaneous publication in The New England Journal of Medicine described important information on the relative risk/benefit of combining anticoagulation with antiplatelet therapy in both coronary artery disease and/or peripheral artery disease (PAD) patients. In this special article, a review of the literature addressing the effects of antiplatelets and anticoagulants in symptomatic PAD patients focusing on the two most relevant clinical endpoints: major adverse cardiovascular events and major adverse limb events is addressed...
August 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29745617/predictors-of-long-term-mortality-following-elective-endovascular-repair-of-abdominal-aortic-aneurysms
#8
Guilherme Marques-Rios, José Oliveira-Pinto, Armando Mansilha
INTRODUCTION: Endovascular aneurysm repair (EVAR) became the preferred modality for abdominal aortic aneurysm (AAA) repair. However, long term survival benefit may sometimes be questionable as many patients would die from other causes rather than aneurysm rupture. It is paramount to identify critical risk factors for late mortality after EVAR to understand its real benefit. The aim of this review is to identify most clinically relevant determinants of late mortality after elective EVAR...
August 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29871479/management-of-chronic-venous-disorders-of-the-lower-limbs-guidelines-according-to-scientific-evidence-part-i
#9
Andrew Nicolaides, Stavros Kakkos, Niels Baekgaard, Anthony Comerota, Marianne de Maesenner, Bo Eklof, Athanasios D Giannoukas, Marzia Lugli, Oscar Maleti, Ken Myers, Olle Nelzén, Hugo Partsch, Michel Perrin
No abstract text is available yet for this article.
June 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29644836/elevated-extracellular-nucleosomes-and-their-relevance-to-inflammation-in-stage-5-chronic-kidney-disease
#10
Trung Phan, Ryan McMillan, Leonidas Skiadopoulos, Amanda Walborn, Debra Hoppensteadt, Jawed Fareed, Vinod Bansal
BACKGROUND: Chronic kidney disease is a disorder characterized by a pro-inflammatory state that is associated with increased morbidity and mortality. Endogenous damage- associated molecular patterns, including nucleosomes, may contribute to this persistent inflammation. The aim of this study was to profile and evaluate the clinical significance of circulating nucleosomes in patients with Stage 5 chronic kidney disease (CKD5) on hemodialysis (HD). METHODS: Under institutional review board approval, plasma samples were collected from 90 CKD5-HD patients (45 male and 45 female) prior to hemodialysis...
April 11, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29644835/risk-assessment-as-a-guide-for-the-prevention-of-cancer-associated-thromboembolism
#11
Ahmed Al-Ogaili, Harry E Fuentes, Alfonso J Tafur, Joseph Caprini
Venous thromboembolism (VTE) is a major source of morbidity and mortality among patients diagnosed with cancer. In addition to an increased risk of VTE, patients with cancer are at higher risk of bleeding while receiving therapeutic anticoagulation. Aggressive and targeted thromboprophylaxis is a crucial practice to avoid the dreaded complications of VTE. Risk assessment models (RAM) are tools developed to identify high-risk patients in whom thromboprophylaxis is beneficial. This review describes the most validated VTE RAMs in patients with cancer...
April 11, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29644834/31p-mr-spectroscopy-of-patients-with-mild-and-serious-lower-limb-ischemia
#12
Petr Sedivy, Miloslav Drobny, Monika Dezortova, Vit Herynek, Karel Roztocil, Helena Cermakova, Andrea Nemcova, Michal Dubsky, Milan Hajek
BACKGROUND: 31P MR spectroscopy is a technique for undertaking a comprehensive evaluation of muscle metabolism. The goal of this study was to compare patients with mild and severe lower limb ischemia measured by 31P MR spectroscopy at rest and during exercise. METHODS: 16 nondiabetic mild peripheral arterial occlusive disease (PAOD) patients, 23 diabetic PAOD patients with severe ischemia and 19 healthy controls were examined by rest and dynamic 31P MR spectroscopy with a 3T MR system equipped with an MR-compatible home-made pedal ergometer...
April 11, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29424187/vascular-malformations-classification-diagnosis-and-treatment
#13
Inês M Carqueja, Joel Sousa, Armando Mansilha
INTRODUCTION: Vascular malformations are congenital lesions with complex clinical presentations and management. Their classification and treatment options have considerably changed throughout the years, with conflicting evidence in the literature. In this article, we aim to review the classification, diagnosis and treatment of the main vascular malformations. EVIDENCE ACQUISITION: A thorough non-systematic review of the literature was conducted using PubMed/Medline...
April 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29424186/spinal-cord-injury-in-endovascular-thoracoabdominal-aortic-aneurysm-repair-prevalence-risk-factors-and-preventive-strategies
#14
Vítor Miranda, Joel Sousa, Armando Mansilha
Thoracoabdominal aortic aneurysms are among the most challenging pathologic conditions vascular surgeons have to face. Endovascular treatment brought the prospect of being able to treat these complex aneurysms with less invasiveness and recent outcomes already challenge those of open repair. Plus, this technique offers a therapeutic option for patients who had none, due to significant comorbidities limiting open repair. Spinal cord injury is a major complication after complex aneurysm repair that dramatically affects patient's quality of life, even if technical success - aneurysm exclusion from circulation - has been achieved...
April 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29385792/efficacy-of-micronized-purified-flavonoid-fraction-daflon%C3%A2-on-improving-individual-symptoms-signs-and-quality-of-life-in-patients-with-chronic-venous-disease-a-systematic-review-and-meta-analysis-of-randomized-double-blind-placebo-controlled-trials
#15
Stavros K Kakkos, Andrew N Nicolaides
INTRODUCTION: The use of a venoactive drug is considered an important component of medical treatment of chronic venous disease (CVD), although the efficacy of certain venoactive drugs (VADs) on one or more individual leg symptoms or signs may have not been extensively studied to justify a strong recommendation in guidelines on CVD. The aim of this systematic review and meta-analysis was to study the effectiveness of the micronized purified flavonoid fraction (MPFF, Daflon®) across the spectrum of defined venous symptoms, signs, quality of life (QoL) and treatment assessment by the physician...
April 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29385791/the-influence-of-patients-nutritional-status-on-the-prevalence-course-and-treatment-outcomes-of-lower-limb-ischemia-an-overview-of-current-evidence
#16
Marta Spychalska-Zwolińska, Tomasz Zwoliński, Marzena Anaszewicz, Jacek Budzyński
INTRODUCTION: The association of lower limb ischemia (LLI) with disturbances in nutritional status, in respect to over- or undernutrition, is still uncertain. The aim of this study was to present the current state of knowledge on this issue. EVIDENCE ACQUISITION: Systematic review of papers published between 2006 and 2018. EVIDENCE SYNTHESIS: The literature shows inconclusive evidence regarding the impact of nutritional status on the risk, course, prognosis and outcomes of conservative and invasive treatment of LLI...
April 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29385790/recurrent-varices-after-surgery-a-clinical-and-color-doppler-ultrasound-scan-analysis
#17
Daniele Bissacco, Enza L Castronovo, Silvia Romagnoli, Maurizio Domanin
BACKGROUND: To evaluate clinical pictures, symptoms and etiology of recurrent varices after surgery (REVAS) through a clinical and color-Doppler-ultrasound scan (CDUS) analysis. METHODS: During a three-year period, data about 9043 consecutive outpatients were collected. Among these, 160 patients (1.8%) were affected by REVAS. Data about risk factors, types of primary vein surgery, symptoms, clinical and CDUS characteristics were analyzed using the Clinical, Etiology, Anatomy and Pathophysiology (CEAP), Stonebridge and Perrin classifications in order to evaluate clinical and anatomical varices patterns...
April 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29376624/investigation-of-non-saphenous-veins-in-c0s-patients
#18
Marzia Lugli, Oscar Maleti, M Letizia Iabichella, Michel Perrin
BACKGROUND: C0S patients have symptoms of chronic venous disorders (CVDs), though an anatomical or pathophysiological explanation is lacking. C0 and C1 classified lower limbs can present with valve incompetence from the second to sixth generation of tributaries of saphenous veins despite the absence of a detectable saphenous truncal reflux. We hypothesized that C0S venous symptoms could stem from the second to sixth generation of saphenous tributaries and small veins that are not connected to the saphenous system...
April 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29327897/peripheral-arterial-occlusive-disease-and-perioperative-risk
#19
Peter Poredos, Pavel Poredos
Surgical procedures represent a risk for different complications which may appear during the perioperative period. Cardiac ischemic events and vascular complications are the most important causes of increased morbidity and mortality and they are much more frequent in patients with manifest cardiovascular disease. This is particularly seen in patients with peripheral arterial occlusive disease (PAD), which represents advanced atherosclerosis frequently accompanied by the presence of coronary artery disease. Therefore, patients with PAD need careful preoperative examination, including estimation of functional capacity and the presence of other co-existing atherosclerotic diseases...
April 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29249118/endovascular-thoracic-aortic-transection-repair-has-equivalent-survival-to-open-repair-after-blunt-thoracic-aortic-injury
#20
Young Erben, Gerardo Trejo, Adam J Brownstein, Raymond A Jean, Bulat A Ziganshin, Davide Carino, John A Elefteriades, Adrian A Maung
BACKGROUND: Blunt thoracic aortic injury (BTAI) is highly lethal and its management has evolved with the advent of endovascular approaches. We hypothesized that endovascular repair (ER) would have equivalent/improved survival compared to open repair (OR). The aim of our study was to review our center's morbidity and mortality after BTAI. METHODS: Our Level I trauma center registry was queried for BTAI between 2002-2015. This cohort was stratified into three groups: ER, OR and those patients managed non-operatively (NOP)...
April 2018: International Angiology: a Journal of the International Union of Angiology
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