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Blood Purification

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https://www.readbyqxmd.com/read/27923227/optimal-role-of-the-nephrologist-in-the-intensive-care-unit
#1
D J Askenazi, Michael Heung, Michael J Connor, Rajit K Basu, Jorge Cerdá, Kent Doi, Jay L Koyner, Azra Bihorac, Ladan Golestaneh, Anitha Vijayan, Mark D Okusa, Sarah Faubel
As advances in Critical Care Medicine continue, critically ill patients are surviving despite the severity of their illness. The incidence of acute kidney injury (AKI) has increased, and its impact on clinical outcomes as well as medical expenditures has been established. The role, indications and technological advancements of renal replacement therapy (RRT) have evolved, allowing more effective therapies with less complications. With these changes, Critical Care Nephrology has become an established specialty, and ongoing collaborations between critical care physicians and nephrologist have improved education of multi-disciplinary team members and patient care in the ICU...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27915351/the-role-of-nephrologist-in-the-intensive-care-unit
#2
Zoltán H Endre
Participation by nephrologists is needed in most intensive care units, even when such units are 'closed'. This participation should assist with diagnosis and management of intrinsic and complex renal diseases such as vasculitis, complex metabolic and electrolyte disorders including hyponatremia, and acute kidney injury (AKI) with and without underlying chronic kidney disease (CKD). Early nephrologist involvement will also facilitate transition to continuing care and follow-up after an episode of AKI, but may also assist in avoiding dialysis where treatment is futile...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27915348/delayed-nephrology-consultation-and-high-mortality-on-acute-kidney-injury-a-meta-analysis
#3
Débora M Soares, José F Pessanha, Aashish Sharma, Alessandra Brocca, Claudio Ronco
BACKGROUND: Acute kidney injury (AKI) is a complex syndrome associated with substantial morbidity, mortality and costs. Despite advancements in diagnosis and care practice, AKI remains a disorder usually under/late-recognized with high mortality. One of the hidden reasons for poor outcome might be delayed nephrology consultation, with the involvement of the specialist only in severe stages of AKI when renal replacement therapy (RRT) is required. METHODS: We searched PubMed, EMBASE and Cochrane central register for related work on the subject...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27915344/intractable-intradialytic-hypotension-with-ischemic-retinopathy
#4
Il Sang Shin, Soo Jeong Choi, Bo Yeon Kim, Jin Kuk Kim, Seung Duk Hwang, Sun Young Jang
No abstract text is available yet for this article.
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27915329/acute-kidney-injury-risk-assessment-and-the-nephrology-rapid-response-team
#5
Lilia Maria Rizo-Topete, Mitchell H Rosner, Claudio Ronco
Acute kidney Injury (AKI) is a serious medical condition affecting more than 10 million people around the world annually and resulting in poor outcomes. It has been suggested that late recognition of the syndrome may lead to delayed interventions with increased morbidity and mortality. Early diagnosis and timely therapeutic strategies may be the cornerstone of future improvement in outcomes. The purpose of this article is to provide a practical model to identify patients at high risk for AKI in different environments, with the goal to prevent AKI...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27915328/critical-care-nephrology-a-multidisciplinary-approach
#6
Lilia Rizo-Topete, Claudio Ronco
Acute kidney injury (AKI) is a serious medical condition affecting millions of people. Patients in intensive care unit (ICU) who develop AKI have increased morbidity and mortality, prolonged length of stay in ICU and hospital and increased costs, especially when they require renal replacement therapy. In the latter case, morbidity and mortality increase further. In order to meet the needs of the critically ill patients, a multidisciplinary care team is required, combining the efforts of physicians and nurses from different disciplines as well as nephrologists and intensivists...
December 3, 2016: Blood Purification
https://www.readbyqxmd.com/read/27875816/serum-magnesium-and-mortality-in-maintenance-hemodialysis-patients
#7
Ling Yu, Han Li, Shi-Xiang Wang
BACKGROUND AND AIM: The study aimed to investigate the potential contributing effect of serum magnesium on mortality in maintenance hemodialysis (MHD) patients. METHODS: The patients receiving regular MHD in March 2013 were involved. Baseline data including clinical data, anthropometrics and biochemical measurement were collected. After being followed for 36 months, the time of death and reason were recorded. RESULTS: One hundred and thirty-five MHD patients were enrolled in the study and analyzed, with mean serum magnesium of 1...
November 23, 2016: Blood Purification
https://www.readbyqxmd.com/read/27875815/wang-s-forceps-assisted-catheter-reposition-and-fixation-an-easy-and-reliable-rescue-method
#8
Huiming Wang, Yujuan Wang, Xinghua Chen, Jili Zhu
Catheter migration and omental wrap are the most common causes of catheter malfunction, which usually result in catheter removal or replacement. The conventional open surgery for catheter reposition has many disadvantages. A new tunnel is needed throughout the procedure of catheter replacement causing more pain and frustration to the patients. Another drawback is that the incidence of catheter migration after conventional catheter reposition surgery is still as high as it was before the procedure. Wang's forceps, an instrument commonly used in our peritoneal dialysis center, is easy and effective in catheter insertion and fixation...
November 23, 2016: Blood Purification
https://www.readbyqxmd.com/read/27875812/hemodialysis-decreases-the-etiologically-related-early-vascular-aging-observed-in-end-stage-renal-disease-a-5-year-follow-up-study
#9
Daniel Bia, Cintia Galli, Yanina Zócalo, Rodolfo Valtuille, Sandra Wray, Ricardo Armentano, Edmundo Cabrera-Fischer
AIMS: To analyze the early vascular aging (EVA) in end-stage renal disease (ESRD) patients, attempting to determine a potential association between EVA and the etiology of ESRD, and to investigate the association of hemodialysis and EVA in ESRD patients during a 5-year follow-up period. METHODS: Carotid-femoral pulse wave velocity (cfPWV) was obtained in 151 chronically hemodialyzed patients (CHP) and 283 control subjects, and in 25 CHP, who were followed-up after a 5-year lapse...
November 23, 2016: Blood Purification
https://www.readbyqxmd.com/read/27875808/increased-soluble-suppression-of-tumorigenicity-2-level-predicts-all-cause-and-cardiovascular-mortality-in-maintenance-hemodialysis-patients-a-prospective-cohort-study
#10
Zhen Zhang, Bo Shen, Xuesen Cao, Zhonghua Liu, Xiaohong Chen, Yuxin Nie, Jinbo Yu, Jianzhou Zou, Xiaoqiang Ding
BACKGROUND: Soluble suppression of tumorigenicity 2 (sST2) is a novel cardiovascular biomarker. This study aimed to evaluate the prognostic value of sST2 in hemodialysis patients. METHODS: Four hundred and fourteen maintenance hemodialysis (MHD) patients were enrolled and followed up prospectively. Serum sST2 levels were measured. The endpoint was all-cause and cardiovascular mortality. RESULTS: During a median follow-up of 22.3 months, 58 patients died, including 31 cardiovascular deaths...
November 23, 2016: Blood Purification
https://www.readbyqxmd.com/read/27846630/a-first-evaluation-of-omni%C3%A2-a-new-device-for-continuous-renal-replacement-therapy
#11
Pierre Schläpfer, Jean-Daniel Durovray, Valery Plouhinec, Cristiano Chiappa, Rinaldo Bellomo, Antoine Schneider
BACKGROUND: Omni® (B. Braun, Germany) is a new-generation, continuous renal replacement therapy (CRRT) machine designed to improve user interface, minimize downtime and optimize renal dose delivery. It was never tested in humans. METHODS: We used Omni® to provide CRRT in 10 critically ill patients. We collected therapy data, metabolic parameters and evaluated user's satisfaction with a survey. RESULTS: CRRT was delivered using Omni® in CVVH-heparin (6 patients) and CVVHD-citrate (4 patients) modes for a total duration of 617...
November 16, 2016: Blood Purification
https://www.readbyqxmd.com/read/27846622/extracorporeal-ultrafiltration-for-acute-heart-failure-lost-battle-or-lasting-opportunity
#12
Abhilash Koratala, Amir Kazory
The negative prognostic impact of congestion and worsening renal function in patients with decompensated heart failure (HF) has been widely recognized. As diuretics are thought to provide suboptimal results and are associated with a number of adverse effects, a number of diuretic-sparing therapeutic strategies have been explored. Extracorporeal ultrafiltration (UF) represents an intriguing option that presumably lacks many of the untoward effects of diuretic-based regimens while portending several advantages...
November 16, 2016: Blood Purification
https://www.readbyqxmd.com/read/27832624/prognostic-biomarkers-at-discontinuation-of-renal-replacement-therapy-in-acute-kidney-injury-patients-in-the-intensive-care-unit
#13
Tingting Yang, Yuliang Zhao, Qiang Liu, Mei Han, Si Sun, Liping Lin, Baihai Su, Songmin Huang
No abstract text is available yet for this article.
November 11, 2016: Blood Purification
https://www.readbyqxmd.com/read/27806355/effects-of-lowering-dialysate-calcium-concentration-on-carotid-intima-media-thickness-and-aortic-stiffness-in-patients-undergoing-maintenance-hemodialysis-a-prospective-study
#14
Zhangxiu He, Lei Cui, Chunyuan Ma, Hong Yan, Tanyong Ma, Lirong Hao
BACKGROUND AND AIM: The study aimed to prospectively evaluate the effects of lowering the dialysate calcium concentration (DCa) to 1.25 mmol/l on Chinese patients undergoing maintenance hemodialysis (MHD), which are largely unknown to date. METHODS: A singer-center, prospective, randomized trial was conducted for 2 years. The DCa in one group was decreased from 1.5 to 1.25 mmol/l but there was no change in the other group. The clinical outcomes, biochemical parameters, medicine treatments and markers of vascular change were compared among the 2 groups at different time intervals...
November 2, 2016: Blood Purification
https://www.readbyqxmd.com/read/27771705/concurrent-hemoperfusion-and-hemodialysis-in-patients-with-acute-pesticide-intoxication
#15
Samel Park, Sunhyo Lee, Suyeon Park, Hyowook Gil, Eunyoung Lee, Jongoh Yang, Saeyong Hong
BACKGROUND: Water soluble and insoluble chemicals in the pesticide formulation may be eliminated more effectively in time if hemodialysis (HD) and hemoperfusion (HP) are performed concurrently. AIM: This study is aimed at evaluating the efficacy of concurrent HP and HD in patients with acute pesticide intoxication. METHODS: Between January 2011 and December 2012, we used HP and HD consecutively (HP-HD group, 347 cases), and then during the next 2 years (January 2013 to December 2014), we used concurrent HP and HD (HPD group, 383 cases)...
October 22, 2016: Blood Purification
https://www.readbyqxmd.com/read/27736815/acute-kidney-injury-electronic-alert-for-nephrologist-reactive-versus-proactive
#16
Kianoush Kashani, Claudio Ronco
Acute kidney injury (AKI) is a common complication of acute illnesses with significant impact on the mortality and morbidity. Early recognition of AKI allows clinicians to provide prophylactic interventions and to improve the outcomes of this deadly syndrome. Growing utilization and capabilities of electronic health records allow AKI risk stratification and early recognition with a potential effect on the processes of care and outcomes. We evaluate the current level of evidence on the impact of the AKI e-alert on the processes of care and outcomes...
October 14, 2016: Blood Purification
https://www.readbyqxmd.com/read/27705977/the-prognostic-value-of-red-blood-cell-distribution-width-in-patients-on-maintenance-hemodialysis
#17
Xiaohong Chen, Bo Shen, Jianzhou Zou, Zhonghua Liu, Wenlv Lv, Xuesen Cao, Jiawei Yu, Yuxin Nie, Jiarui Xu, Li Wang, Xiaoqiang Ding
AIMS: To examine the association between red blood cell distribution width (RDW) and mortality in hemodialysis (HD) patients. METHODS: Three hundred fifty six patients on HD for >3 months were enrolled and followed for 2 years. Patients were divided into 2 groups according to the median RDW value. Patient survival and risk factors for mortality were investigated. RESULTS: The 2-year survival rate was significantly lower in the high-RDW group (>14...
October 6, 2016: Blood Purification
https://www.readbyqxmd.com/read/27705976/contrast-enhanced-ct-scans-should-be-permitted-in-peritoneal-dialysis-patients-when-indicated-with-precautions
#18
Srinivas Subramanian, Muhammad Masoom Javaid
No abstract text is available yet for this article.
October 6, 2016: Blood Purification
https://www.readbyqxmd.com/read/27694753/the-influence-of-hemodialysis-on-t-regulatory-cells-a-meta-analysis-and-systematic-review
#19
Carlotta Caprara, Gilbert R Kinsey, Valentina Corradi, Wenjun Xin, Jennie Z Ma, Elisa Scalzotto, Francesca K Martino, Mark D Okusa, Federico Nalesso, Fiorenza Ferrari, Mitchell Rosner, Claudio Ronco
AIMS: The study aimed to determine whether the available literature supports a positive or negative influence of dialysis on regulatory T-cells (Tregs). METHODS: We performed a systematic search and a meta-analysis. Mean differences in Tregs number of chronic kidney disease stages G5 on dialysis patients (CKD G5D) and healthy controls (HCs) were compared. Random effects model was applied. The software used was general package for meta-analysis (version 4.3-0, depends R (≥2...
October 1, 2016: Blood Purification
https://www.readbyqxmd.com/read/27577953/serum-endotoxin-activity-measured-with-endotoxin-activity-assay-is-associated-with-serum-interleukin-6-levels-in-patients-on-chronic-hemodialysis
#20
Maurizio Bossola, Enrico Di Stasio, Maurizio Sanguinetti, Brunella Posteraro, Manuela Antocicco, Gilda Pepe, Enrica Mello, Francesca Bugli, Carlo Vulpio
BACKGROUND: This study aims to evaluate, in patients on chronic hemodialysis (PHD), the levels of endotoxin through a chemiluminescent bioassay based on the oxidative burst reaction of activated neutrophils to complement coated LPS-IgM immune complexes and define the variables possibly correlated. METHODS: In 61 PHD, we measured serum endotoxin activity (EA) with the Endotoxin Activity Assay (EAA™) and we defined the possible association with demographic, clinical and laboratory variables...
August 31, 2016: Blood Purification
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