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Blood Purification

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https://www.readbyqxmd.com/read/28334722/even-a-moderate-fluid-removal-rate-during-individualised-haemodialysis-session-times-is-associated-with-decreased-patient-survival
#1
Charles Chazot, Cyril Vo-Van, Christie Lorriaux, Patrik Deleaval, Brice Mayor, Jean-Marc Hurot, Guillaume Jean
BACKGROUND: Several studies report that fluid removal rate (FRR) above 10-13 mL/h/kg is associated with increased mortality in haemodialysis (HD) patients. AIM: The aims of this study are to assess the influence of moderate FRR on survival in a cohort of prevalent dialysis patients with various dialysis session times and to challenge the FRR thresholds associated with increased mortality risk reported previously. METHODS: Interdialytic weight gain (IDWG) and FRR (calculated from ultrafiltration [UF], target weight, and session time prescriptions) were studied in 190 prevalent dialysis patients (female: 42%, mean age: 69...
March 24, 2017: Blood Purification
https://www.readbyqxmd.com/read/28268216/exit-site-infection-in-peritoneal-dialysis-need-for-follow-up-on-cultures-despite-clinical-improvement
#2
Abhilash Koratala, Volodymyr Chornyy, Amir Kazory
No abstract text is available yet for this article.
March 8, 2017: Blood Purification
https://www.readbyqxmd.com/read/28268210/leveraging-big-data-and-electronic-health-records-to-enhance-novel-approaches-to-acute-kidney-injury-research-and-care
#3
Scott M Sutherland, Stuart L Goldstein, Sean M Bagshaw
While acute kidney injury (AKI) has been poorly defined historically, a decade of effort has culminated in a standardized, consensus definition. In parallel, electronic health records (EHRs) have been adopted with greater regularity, clinical informatics approaches have been refined, and the field of EHR-enabled care improvement and research has burgeoned. Although both fields have matured in isolation, uniting the 2 has the capacity to redefine AKI-related care and research. This article describes how the application of a consistent AKI definition to the EHR dataset can accurately and rapidly diagnose and identify AKI events...
March 8, 2017: Blood Purification
https://www.readbyqxmd.com/read/28253497/comparison-of-the-an69st-membrane-versus-citrate-enriched-dialysate-on-clotting-events-during-hemodialysis-without-systemic-anticoagulation
#4
Vanessa Nseir, Antoine Rachas, Michelle Elias, Hélène Francois, Erika Nnang Obada, Hans Kristian Lorenzo, Bernard Charpentier, Antoine Durrbach, Séverine Beaudreuil
BACKGROUND: The optimal management of anticoagulation in hemodialyzed patients with a high risk of bleeding is controversial. METHODS: We compared premature termination of dialysis caused by clotting events between AN69ST membranes (G1) and 0.8 mmol/L citrate-enriched dialysate (G2). The number of sessions that had increased venous pressure (VP) and variations in urea-reduction ratio (URR) were analyzed. RESULTS: Six hundred and two sessions were analyzed in 259 patients: 22...
March 3, 2017: Blood Purification
https://www.readbyqxmd.com/read/28249254/evaluation-of-the-impact-of-a-new-synthetic-vitamin-e-bonded-membrane-on-the-hypo-responsiveness-to-the-erythropoietin-therapy-in-hemodialysis-patients-a-multicenter-study
#5
Francesco Locatelli, Simeone Andrulli, Sara Maria Viganò, Massimo Concetti, Sauro Urbini, Franca Giacchino, Roberto Broccoli, Filippo Aucella, Maria Cossu, Paolo Conti, Laura Fattori, Giorgio Punzo, Daniela Angelini, Marco Peruzzini, Salvatore Di Giulio, Marta Piroddi, Francesco Galli, Lucia Del Vecchio
BACKGROUND: Oxidative stress has been related to hypo-response to erythropoiesis-stimulating agents (ESAs) in hemodialysis (HD) patients. The aim of this study was to verify whether vitamin E (ViE) on a synthetic polysulfone dialyzer can improve ESA responsiveness. METHODS: This controlled, multicenter study involved 93 HD patients on stable ESA therapy, who were randomized to either ViE-coated polysulfone dialyzer or to a low-flux synthetic dialyzer. The primary outcome measure was the change in ESA resistance index (ERI) from baseline...
March 2, 2017: Blood Purification
https://www.readbyqxmd.com/read/28241128/effects-of-blood-purification-on-serum-levels-of-inflammatory-cytokines-and-cardiac-function-in-a-rat-model-of-sepsis
#6
Cong-Meng Lin, Cun-Rong Chen, Xue-Qiong Wu, Jin-Hua Ren, Shao-Zhen Chen, Xiao-Feng Luo, Xu-Qiao Mei, Lv-Ying Shen, Meng-Xian Guo, Xu-Dong Ma, Ting Yang
OBJECTIVE: The study aimed to explore the effects of blood purification (BP) on serum levels of inflammatory cytokines and cardiac function in a rat model of sepsis. METHODS: A rat model of sepsis was established by cecal ligation and puncture. All rats were divided into the normal control, sham operation, model, sham treatment, and BP treatment groups. Cardiac functions, inflammatory cytokines, myocardial enzymes, pathological score of cardiac muscle tissue, and myocardial apoptosis of rats in each group were compared...
February 28, 2017: Blood Purification
https://www.readbyqxmd.com/read/28241125/the-effect-of-intra-dialytic-exercise-on-inflammation-and-blood-endotoxin-levels
#7
Jonathan Wong, Philip Davis, Ashish Patidar, Yonglong Zhang, Enric Vilar, Malcolm Finkelman, Ken Farrington
BACKGROUND: In healthy individuals, an acute inflammatory response occurs after intense exercise due to gut ischaemia and intestinal bacterial endotoxin translocation into the bloodstream. This process maybe exacerbated in patients who exercise during dialysis due to large volume shifts experienced by many during haemodialysis (HD). The acute effect of intra-dialytic exercise on blood endotoxins and inflammation is not known. METHOD: The effect of intra-dialytic exercise on blood endotoxin and inflammation was investigated in 10 patients and compared with resting haemodialysis...
February 28, 2017: Blood Purification
https://www.readbyqxmd.com/read/28237986/relationship-among-mortality-of-patients-with-acute-kidney-injury-after-cardiac-surgery-fluid-balance-and-ultrafiltration-of-renal-replacement-therapy-an-observational-study
#8
Buyun Wu, Jian Sun, Si Liu, Xiangbao Yu, Yamei Zhu, Huijuan Mao, Changying Xing
BACKGROUND/AIMS: The study aimed to investigate the relationship among mortality of patients with cardiac surgery-associated acute kidney injury (CSA-AKI), fluid balance, and ultrafiltration of renal replacement therapy (RRT). METHODS: From January 2009 to October 2015, hospitalized patients with CSA-AKI receiving continuous or prolonged intermittent RRT were screened. The effects of fluid balance and ultrafiltration of RRT on clinical outcome were analyzed. RESULTS: The 30-day mortality of all the 63 patients in the study was 58...
February 25, 2017: Blood Purification
https://www.readbyqxmd.com/read/28237983/effects-of-cardiac-function-with-postoperative-arteriovenous-fistula-blood-flow-in-patients-with-hemodialysis
#9
Keiichi Wakabayashi, Hiroaki Io, Junichiro Nakata, Hirotaka Nakamoto, Michiko Sato, Yu Sasaki, Yoshio Shimizu, Satoshi Horikoshi, Yasuhiko Tomino, Yusuke Suzuki
BACKGROUND/AIMS: This study was aimed at evaluating the effect of cardiac function with postoperative arteriovenous fistula (AVF) blood flow in hemodialysis (HD) patients. METHODS: A total of 45 HD patients were examined at the Juntendo University Hospital. The AVF blood flow was measured using ultrasonography, and the cardiac function was measured using echocardiography. Correlation between these parameters and the rate of change in body weight (BW) was analyzed...
February 25, 2017: Blood Purification
https://www.readbyqxmd.com/read/28237981/ex-vivo-ceftolozane-tazobactam-clearance-during-continuous-renal-replacement-therapy
#10
Weerachai Chaijamorn, Alexander R Shaw, Susan J Lewis, Bruce A Mueller
BACKGROUND/AIMS: To determine ceftolozane/tazobactam transmembrane clearances (CLTM) in continuous hemofiltration (CHF) and continuous hemodialysis (CHD) and to determine optimal ceftolozane/tazobactam dosing regimens for patients receiving continuous renal replacement therapy (CRRT). METHOD: Validated, ex vivo CHF and CHD bovine blood models using polysulfone (HF1400) and AN69 (Multiflow 150-M) hemofilters were used to evaluate adsorption and CLTM at different effluent flow rates...
February 25, 2017: Blood Purification
https://www.readbyqxmd.com/read/28237980/application-of-hemoadsorption-in-a-case-of-liver-cirrhosis-and-alcohol-related-steatohepatitis-with-preexisting-hepatitis-c-infection
#11
Stefan Büttner, Sammy Patyna, Benjamin Koch, Fabian Finkelmeier, Helmut Geiger, Christoph Sarrazin, Harald Farnik
No abstract text is available yet for this article.
February 25, 2017: Blood Purification
https://www.readbyqxmd.com/read/28226325/lung-ultrasound-in-hemodialysis-a-card-to-be-played
#12
Pierpaolo Di Nicolò, Giacomo Magnoni, Antonio Granata
The end-stage renal disease is characterized by a profound impairment in the regulation of body fluid distribution, and volume assessment in hemodialysis is one of the challenging goals for the nephrologist. To determine a state of euvolemia, different validated techniques have been employed and among them lung ultrasonography (LUS) has recently attracted growing attention on account of its capacity to estimate accurately extra vascular lung water and to detect lung edema even in its early asymptomatic stage, that is, hidden lung congestion...
February 23, 2017: Blood Purification
https://www.readbyqxmd.com/read/28219057/preventing-continuous-renal-replacement-therapy-induced-hypophosphatemia-an-extended-clinical-experience-with-a-phosphate-containing-solution-in-the-setting-of-regional-citrate-anticoagulation
#13
Valentina Pistolesi, Laura Zeppilli, Francesca Polistena, Maria Itala Sacco, Alessandro Pierucci, Luigi Tritapepe, Giuseppe Regolisti, Enrico Fiaccadori, Santo Morabito
AIMS: To evaluate the efficacy and safety of a commercially available phosphate-containing solution for continuous renal replacement therapy (CRRT) in preventing CRRT-related hypophosphatemia. METHODS: In heart surgery patients undergoing continuous veno-venous haemodiafiltration (CVVHDF) with regional citrate anticoagulation (RCA), we combined an 18 mmol/l citrate solution with a phosphate-containing (1.2 mmol/l) dialysate/replacement fluid evaluating the incidence of hypophosphatemia and the need for parenteral phosphorus supplementation...
February 21, 2017: Blood Purification
https://www.readbyqxmd.com/read/28192778/annual-congress-of-the-blood-purification-management-branch-of-chinese-hospital-society-august-11-14-2016-nanjing-china-selected-abstracts
#14
(no author information available yet)
No abstract text is available yet for this article.
February 14, 2017: Blood Purification
https://www.readbyqxmd.com/read/28142133/perioperative-hemodynamic-instability-and-fluid-overload-are-associated-with-increasing-acute-kidney-injury-severity-and-worse-outcome-after-cardiac-surgery
#15
Anja Haase-Fielitz, Michael Haase, Rinaldo Bellomo, Paolo Calzavacca, Anke Spura, Hassina Baraki, Ingo Kutschka, Christian Albert
PURPOSE: The study aimed to investigate patients' characteristics, fluid and hemodynamic management, and outcomes according to the severity of cardiac surgery-associated acute kidney injury (CSA-AKI). METHODS: In a single-center, prospective cohort study, we enrolled 282 adult cardiac surgical patients. In a secondary analysis, we assessed preoperative patients' characteristics, physiological variables, and medication for intra- and postoperative fluid and hemodynamic management and outcomes according to CSA-AKI stages by the Renal risk, Injury, Failure, Loss, End-stage renal disease (RIFLE) classification...
January 31, 2017: Blood Purification
https://www.readbyqxmd.com/read/28135706/the-different-impacts-on-the-long-term-survival-of-tunneled-internal-jugular-hemodialysis-catheters-based-on-tip-position-and-laterality
#16
Vedran Premuzic, Drazen Perkov, Ranko Smiljanic, Bruna Brunetta Gavranic, Bojan Jelakovic
BACKGROUND/AIMS: The aim of this study was to examine the impact of different catheter tip positions on the life of the catheter, dysfunction, infection, and quality of hemodialysis and possible differences between the access site laterality in jugular-tunneled hemodialysis catheters. METHODS: Catheters were evaluated for the following parameters: place of insertion, time of insertion, duration of use, and reason for removal. In all patients, the catheter tip position was checked using an X-ray...
January 31, 2017: Blood Purification
https://www.readbyqxmd.com/read/28135703/vascular-refilling-is-not-reduced-in-dialysis-sessions-with-morbid-events
#17
Susanne Kron, Daniel Schneditz, Til Leimbach, Sabine Aign, Joachim Kron
BACKGROUND: It is commonly believed that insufficient vascular refilling leads to hypovolemia during hemodialysis and contributes to intradialytic morbid events (IME). But data of refilling volumes at the time of IME are lacking. METHODS: We compared the vascular refilling in 10 patients with IME with 14 stable patients with normal blood volume at the dialysis end (66-80 mL/kg). RESULTS: The refilling characteristics in patients with IME did not differ from those in stable patients...
January 31, 2017: Blood Purification
https://www.readbyqxmd.com/read/28135701/catheter-failure-and-mortality-in-hemodialysis-patients-with-tunneled-cuffed-venous-catheters-in-a-single-center
#18
Min Shi, Tianlei Cui, Liang Ma, Li Zhou, Ping Fu
BACKGROUND: As of now, only a few studies have focused on the failure of tunneled cuffed venous catheter (tCVC) and mortality of hemodialysis (HD) patients using tCVC as long-term vascular access, whose vascular condition for arteriovenous fistula was not very satisfactory. In this study, we aimed to provide information about the first tCVC failure and survival rates of patients in this population. METHODS: Fifty-nine patients who used tCVC from January 1, 2009 to December 31, 2014 in our HD center were analyzed in this retrospective study and followed up either until their death or until December 31, 2015...
January 31, 2017: Blood Purification
https://www.readbyqxmd.com/read/28125806/procalcitonin-and-interleukin-6-levels-are-they-useful-biomarkers-in-cardiac-surgery-patients
#19
Anna Clementi, Alessandra Brocca, Grazia Maria Virzì, Massimo de Cal, Davide Giavarina, Mariarosa Carta, María-Jimena Muciño-Bermejo, Tommaso Hinna Danesi, Loris Salvador, Claudio Ronco
BACKGROUND/AIM: Cardiac surgery-associated acute kidney injury is an independent predictor of chronic renal disease and mortality. The scope of this study was to determine the utility of procalcitonin (PCT) and plasma interleukin-6 (IL-6) levels in predicting renal outcome and mortality in these patients. METHODS: PCT and plasma IL-6 levels of 122 cardiac surgery patients were measured at 48 h after the surgical procedure. Primary endpoints were adverse renal outcome and mortality...
January 25, 2017: Blood Purification
https://www.readbyqxmd.com/read/28118627/prostacyclin-as-an-anticoagulant-for-continuous-renal-replacement-therapy-in-children
#20
Akash Deep, Mohammad Zoha, Pompa Dutta Kukreja
Effective delivery of continuous renal replacement therapy (CRRT) depends on the longevity of the filter and circuit used in the CRRT machine. Safe and effective anticoagulation is crucial for maintaining the patency of these circuits. In children, heparin and citrate are the commonly used anticoagulants but they are limited by serious side effects and thus calls for meticulous monitoring. In conditions where neither of these can be used, prostacyclin can be an effective alternative. Prostacyclin is a platelet inhibitor that can be safely used as an efficient anticoagulant in CRRT...
January 25, 2017: Blood Purification
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