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Asian Pacific Journal of Allergy and Immunology

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https://www.readbyqxmd.com/read/28364412/the-validation-and-evaluation-of-anti-hiv-testing-algorithm-used-in-mobile-clinic-setting-for-men-who-have-sex-with-men-in-metropolitan-bangkok-thailand
#1
Tippawan Pankam, Sarun Saensiriphan, Suphackok Areeyolwattana, Napapat Barisri, Supabhorn Pengnonyang, Sunee Sirivichayakul, Nittaya Phanuphak, Praphan Phanuphak
BACKGROUND: Same-day anti-HIV testing algorithm is recommended by Thai National Guidelines. We compared performance characteristics of algorithms used in a mobile clinic and a facility-based clinic for men who have sex with men (MSM) in Bangkok. METHODS: Mobile clinic samples collected from 4 saunas and 2 spa venues were tested by Alere DetermineTM HIV 1/2, followed by DoubleCheck GoldTM Ultra HIV 1/2 and SD Bioline HIV 1/2 3.0. All samples were re-tested at the Thai Red Cross Anonymous Clinic (TRCAC) by Architect HIV Ag/Ab or Elecsys HIV combi PT, followed by Alere DetermineTM HIV 1/2 and Serodia HIV 1/2...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28364411/urinary-cysteinyl-leukotriene-e4-level-and-therapeutic-response-to-montelukast-in-children-with-mild-obstructive-sleep-apnea
#2
Kanokkarn Sunkonkit, Suchada Sritippayawan, Montida Veeravikrom, Jitladda Deerojanawong, Nuanchan Prapphal
BACKGROUND: Antileukotriene has been used for alleviating disease severity in children with adenotonsillar hypertrophy (ATH) and mild obstructive sleep apnea (OSA). Previous study showed the relationship between urinary cysteinyl leukotriene E₄ (uLTE₄) level and therapeutic response to montelukast in asthmatic adults. However, this relationship has never been investigated in pediatric OSA. OBJECTIVES: To determine the relationship between uLTE₄ level and therapeutic response to montelukast in children with ATH and mild OSA...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28364410/association-analyses-identify-two-susceptibility-loci-5q31-and-5q22-1-for-atopic-dermatitis-in-chinese-han-population
#3
Xiao-Yun Jiang, Jin-Hua Zhao, Chong-Xian Yu, Ling Fang, Xiao-Dong Zheng, Xian-Yong Yin, Yan-Yan Wu, Xian-Fa Tang, Fu-Sheng Zhou, Xue-Jun Zhang, Feng-Li Xiao
BACKGROUND: Atopic dermatitis (AD) and other atopic diseases often share some common genetic and pathogenic bases. Recent genome-wide association studies (GWAS) have identified several loci associated with atopic diseases, allergic sensitization and asthma in different populations. The aim of this study was to investigate whether these susceptibility loci were related to AD in Chinese Han population. METHODS: Eight single nucleotide polymorphisms (SNPs) from recent atopic diseases and allergic sensitization GWAS were genotyped in 3,013 AD patients and 5,483 healthy controls in Chinese Han population using Sequenom MassArray system...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28364409/metabolomics-analysis-of-anaphylactoid-reaction-reveals-its-mechanism-in-a-rat-model
#4
Yubin Xu, Na Guo, Deqiang Dou, Xiaoku Ran, Chunyan Liu
BACKGROUND: Anaphylactoid reactions, accounting for more than 77% of all immune-mediated immediate hypersensitivity reactions, have become a serious threat to public health, but their effect mechanism is not clear and diagnostic tests are limited. Comprehensive metabolite analysis may reveal the anaphylactoid effect mechanism systematically and provide reference for future diagnostic purposes. METHODS: Plasma from Brown Norway rats given intravenous injection of saline, compound 48/80 (2...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28364408/comparison-of-the-efficacy-and-safety-of-pollen-allergen-extracts-using-skin-prick-testing-and-serum-specific-ige-as-references
#5
Nualanong Visitsunthorn, Kittipos Visitsuntho, Punchama Pacharn, Orathai Jirapongsananuruk, Chaweewan Bunnag
BACKGROUND: Allergen extracts may be different due to the difference in dissemination of allergen-containing species in various geographical areas. Therefore, we wish to develop our own extracts to ensure the precision and quality of diagnosis. OBJECTIVES: To compare the efficacy and safety of our locally prepared pollen allergen extracts to imported ones, using skin prick testing (SPT) and serum specific IgE (sIgE) as references. METHODS: This prospective, randomized, double-blinded, self-controlled study was performed in respiratory allergic adult volunteers who are sensitized to at least one kind of pollen...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28364407/mosquito-allergy-in-children-clinical-features-and-limitation-of-commercially-available-diagnostic-tests
#6
Wiparat Manuyakorn, Sulak Itsaradisaikul, Suwat Benjaponpitak, Wasu Kamchaisatian, Cherapat Sasisakulporn, Wanlapa Jotikasthira, Ponpan Matangkasombut
OBJECTIVE: To determine the clinical features of mosquito allergy in children and the ability of commercially available mosquito allergy tests to detect children with mosquito allergy in Thailand. METHODS: Patients with mosquito allergy aged 1 month to 18 years were recruited. Demographic data, history of mosquito allergy (onset of the reaction, reaction type) and clinical features were recorded. A skin prick test using a commercially available whole body allergen extract from Culex pipiens was performed, and serum was tested for specific IgE antibodies to Aedes communis whole body extract...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28364406/component-resolved-diagnostics-in-thai-children-with-cow-s-milk-and-egg-allergy
#7
Wipa Jessadapakorn, Pasuree Sangsupawanich, Natthakul Wootipoom, Oranart Suddeaugrai, Araya Yuenyongviwat
BACKGROUND AND OBJECTIVE: Component-resolved diagnostics (CRD) have garnered a lot of attention in recent years in the diagnosis of food allergies. We aimed to investigate sensitization against cow's milk and egg white components, and to study the clinical usefulness of serum food-specific immunoglobulin E (sIgE) to cow's milk and egg white components in Thai children with cow's milk and egg allergies. METHOD: Children with IgE-mediated cow's milk and/or egg allergy were enrolled...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28431472/erratum-figure-correction-aeroallergen-sensitization-and-allergic-disease-phenotypes-in-asia
#8
(no author information available yet)
To the Editor: We would like to make a minor geographical correction to the map in the original article. The revised map is attached (Figure 1). The aeroallergen sensitization distributions remain accurate and this correction does not change the scientific conclusions of the article in any way. The authors take responsibility for the error.
March 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28431471/asthma-copd-overlap-syndrome-and-precision-medicine
#9
Somchai Bovornkitti
No abstract text is available yet for this article.
March 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27362403/fraction-of-exhaled-nitric-oxide-and-soluble-receptors-for-advanced-glycation-end-products-are-negatively-correlated-in-children-with-recurrent-wheezing
#10
Yuhong Li, Rong Wu, Yian Tian, Tianping Bao, Zhaofang Tian
BACKGROUND: The fraction of exhaled nitric oxide (FeNO) and serum levels of the soluble receptor for advanced glycation end products (sRAGE) have been suggested as biomarkers for asthma. OBJECTIVE: This study aimed to assess the correlation between FeNO and sRAGE serum levels in children <5 years old with recurrent wheezing. METHOD: In total, 88 children with recurrent wheezing were divided into the high-risk group or low-risk group according to their clinical features...
March 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996292/activation-of-dengue-virus-specific-t-cells-modulates-vascular-endothelial-growth-factor-receptor-2-expression
#11
Jittraporn Rattanamahaphoom, Pornsawan Leaungwutiwong, Kriengsak Limkittikul, Nathamon Kosoltanapiwat, Anon Srikaitkhachorn
BACKGROUND: The pathogenic mechanisms underlying the increased vascular permeability in dengue hemorrhagic fever (DHF) are not well understood. Enhanced cellular immune activation, especially activation of serotype-cross reactive T cells, has been implicated in plasma leakage in DHF. Changes in several biological markers and mediators including cytokines, chemokines, angiogenic factors and their receptors have been shown to correlate with disease severity. A decline in plasma levels of a soluble form of vascular endothelial growth factor receptor 2 (VEGFR2), a receptor of vascular endothelial growth factor (VEGF), has been associated with plasma leakage in dengue patients...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996291/is-the-prevalence-of-atopic-dermatitis-in-korean-children-decreasing-analysis-of-the-national-statistics-data-2009-2014
#12
Ji Young Lee, Hea-Kyoung Yang, Minji Kim, Jihyun Kim, Kangmo Ahn
BACKGROUND: The prevalence of atopic dermatitis (AD) in children is increasing in many developing countries. OBJECTIVE: This study aimed to explore trends in the prevalence of AD in Korean children. METHODS: We analyzed data from the Korean National Health Insurance Service from 2009 to 2014. Data for the estimated populations were collected from the Statistics Korea. The annual prevalence of AD was obtained by dividing the number of patients by the estimated population each year...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996290/determination-of-fractional-exhaled-nitric-oxide-feno-reference-values-in-healthy-thai-population
#13
Yiwa Suksawat, Punchama Pacharn, Orathai Jirapongsananuruk
BACKGROUND: Fractional exhaled nitric oxide (FENO) level is directly correlated with airway inflammation in asthma patients. The objective of this study was to define normal FENO levels in healthy Thai volunteers. METHODS: This prospective cohort study was conducted in healthy Thai volunteers aged ≥5 years. Demographic and clinical data were recorded and pulmonary function test (PFT) was performed. FENO was measured using a chemiluminescence nitric oxide analyzer...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996289/cardiac-involvement-in-dress-syndrome
#14
Tomon Thongsri, Leena Chularojanamontri, Werner J Pichler
OBJECTIVE: Cardiac involvement in drug rash with eosinophilia and systemic symptoms (DRESS) syndrome varies considerably between 4% and 21%. Here we present our case and review literatures for its diagnosis and management. An algorithm for diagnosis of cardiac involvement in DRESS syndrome is proposed in this article. DATA SOURCES: Data regarding DRESS-associated myocarditis and eosinophilic myocarditis were gather primarily from MEDLINE database. RESULTS: DRESS syndrome is a hypersensitivity reaction which is due to massive T cell stimulation resulting in cytotoxicity and eosinophil activation and recruitment...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996288/the-natural-history-of-atopic-dermatitis-and-its-association-with-atopic-march
#15
Sinjira Somanunt, Sasawan Chinratanapisit, Punchama Pacharn, Nualanong Visitsunthorn, Orathai Jirapongsananuruk
BACKGROUND: Atopic dermatitis (AD) is the first manifestation of Atopic March. The natural history of AD and predictive factors for Atopic March have not been widely studied in Asia. OBJECTIVE: To study the natural history and associated factors of disease remission and risk of respiratory allergy in Thai children with AD. METHOD: Medical records of AD patients attending Allergy clinic at Siriraj hospital from 2004-2014 were reviewed. Patients were further followed-up to obtain current symptoms and treatment...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996287/association-of-indoor-air-quality-and-preschool-children-s-respiratory-symptoms
#16
Pongtong Puranitee, Sirinapa Siwarom, Adisak Plitponkarnpim, Wiparat Manuyakorn, Ratchaneewan Sinitkul, Sakda Arj-Ong Vallipakorn
BACKGROUND: This study aimed to assess the association between exposure to indoor air pollution in DCCs (Child Day Care Centers) and the respiratory symptoms of children under 6 years old. METHODS: Air quality data were collected three times regarding seasonal variation. Pollutants measured in 11 DCCs included PM10, CO, NO2, SO2, O3, benzene, bacteria, fungi, and dust mite. The frequency of respiratory symptoms including coughing, rhinitis, and dyspnea were recorded via teacher and parent-report questionnaires...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996286/safety-and-efficacy-of-ant-rush-immunotherapy-in-children
#17
Wiparat Manuyakorn, Suwat Benjaponpitak, Wasu Kamchaisatian, Cherapat Sasisakulporn, Wanlapa Jotikasthira
BACKGROUND: The Rush Immunotherapy (RIT) protocol is a valid alternative in order to reach the maintenance phase early. However, there are scarce studies in the literature that have evaluated the safety and the efficacy of an ant RIT process in children. OBJECTIVE: To evaluate the safety and the efficacy of an ant RIT protocol and to identify the risk factors for systemic reactions (SRs) during an RIT procedure in children. METHOD: A retrospective review was conducted for those children who were receiving an ant RIT procedure...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996285/bcap-31-expression-and-promoter-demethylation-in-psoriasis
#18
Kriangsak Ruchusatsawat, Laddawan Thiemsing, Apiwat Mutirangura, Jongkonnee Wongpiyabovorn
BACKGROUND: Psoriasis is the disease of abnormal keratinocyte differentiation and apoptosis. Alterations in DNA methylation leading to keratinocyte hyperproliferation is one of the proposed pathogenic mechanisms of psoriasis. B-cell receptor associated protein (BCAP31) has been reported to be involved in the proliferation and apoptosis of keratinocytes. Up-regulation and changing in BCAP31 promoter methylation has been reported to be associated with some cancers. To date, there has been no study of psoriasis...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996284/allergic-sensitization-in-kidney-transplanted-patients-is-it-a-result-of-immunosuppressive-agents-or-sensitization-of-the-living-donor
#19
Dilek Doğruel, Aytül Noyan, Hasan Dursun, Nurcan Cengiz
BACKGROUND: Allergic sensitization has been reported increasingly in organ transplant recipients. However, the pathogenesis of this sensitization has still not been clearly understood. OBJECTIVE: The aim of this study was to evaluate allergic sensitization in kidney transplanted children and adolescents under immunosuppressive treatment. METHODS: Twenty seven kidney-transplanted subjects were studied by standardized interviews from the International Study of Asthma and Allergies in Childhood criteria, skin prick test (SPT) and measurement of specific immunoglobulin E (s-IgE)...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996283/evaluation-of-serum-interleukin-35-level-in-children-with-persistent-asthma
#20
Nazila Ariaee, Maryam Khoshkhooy, Soheyla Alyasin, Eskandar Kamali Sarvestani, Reza Amin
BACKGROUND: IL-35 is a novel cytokine suppressing the immune response through the expansion of regulatory T cells and suppression of Th17 cell development. Few studies have been done on the effect of this cytokine in a different disease. Asthma is a complex disease that many inflammatory cells and cytokines play a role in. OBJECTIVE: We decide to determine the difference between serum level of IL-35 in childhood asthma & healthy children. METHODS: We obtained serum samples from 44 asthmatic children between 2 and 15 years as a case group and from healthy children as a control group...
December 12, 2016: Asian Pacific Journal of Allergy and Immunology
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