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Asian Pacific Journal of Allergy and Immunology

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https://www.readbyqxmd.com/read/28938843/comparison-of-specific-ige-detection-by-immunoblotting-and-fluorescence-enzyme-assay-with-in-vivo-skin-prick-test
#1
Jongkonnee Wongpiyabovorn, Narissara Suratannon, Sadudee Boonmee, Pantipa Chatchatee
BACKGROUND: Diagnostic tools to identify allergens that cause allergic symptom is important part in the care of allergic patients. Detection of causative allergen can be performed by in vivo skin prick test (SPT) or in vitro tests for detection serum specific immunoglobulin E (sIgE). The common methods used are fluorescent enzyme assay and immunoblotting assay. OBJECTIVE: We aim to evaluate performance of the two sIgE determination systems, immunoblotting assay (Euroline) and fluorescent enzyme assay (ImmunoCAP) in comparison with SPT...
September 17, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28938842/small-plaque-size-variant-of-chikungunya-primary-isolate-showed-reduced-virulence-in-mice
#2
Thitigun Jaimipak, Sutee Yoksan, Sukathida Ubol, Rojjanaporn Pulmanausahakul
BACKGROUND: Plaque size is a common feature of viral characterization. Small plaque size is used as a marker of attenuation for live-attenuated vaccine development. OBJECTIVE: To investigate whether the naturally occurring plaque size variation reflects virulence of the variants of chikungunya virus (CHIKV). METHODS: We selected and purified a variant with small plaque size from the primary isolate. The viral variant was tested for the plaque morphology, in vitro growth kinetics and mouse neurovirulence in comparison with the parental wild type...
September 17, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28938841/elevated-fecal-calprotectin-levels-are-associated-with-severity-of-atopic-dermatitis-in-children
#3
Sung Chul Seo, So Hyun Ahn, Soohyun Ri, Yoonsun Yoon, Jung Hye Byeon, Seung Hyun Kim, Wonsuck Yoon, Young Yoo
BACKGROUND: Recent data suggested that imbalance in gut microbiota and gastrointestinal inflammation are associated with the childhood allergic disease. Fecal calprotectin has been used for a non-invasive marker of gut inflammation. OBJECTIVE: The aim of this study was to investigate the relationships between fecal calprotectin level and the clinical severity of atopic dermatitis (AD) in children. METHODS: We enrolled 65 subjects with AD. The concentration of calprotectin was measured in each subject's fecal sample...
September 17, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28938840/first-episode-of-preschool-wheeze-requiring-hospitalization-a-prospective-study-on-the-chance-of-recurrence-and-associated-factors
#4
Karaked Chantawarangul, Jitladda Deerojanawong, Suchada Sritippayawan
BACKGROUND: Although wheezing is very common in preschoolers, epidemiologic studies in Thailand are quite limited. The likelihood of having a second wheezing episode following the first attack remains unclearly established. OBJECTIVES: This study aims to investigate the incidence of recurrent wheezing in preschool children presenting with first wheezing episode and identify the associated factors. METHODS: The study is an observational prospective study conducted at the inpatient pediatric department...
September 17, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28938839/needle-length-for-epinephrine-prefilled-syringes-in-children-and-adolescents-is-it-one-inch
#5
Wiparat Manuyakorn, Buntita Bamrungchaowkasem, Nichanan Ruangwattanapaisarn, Wasu Kamchaisatian, Suwat Benjaponpitak
BACKGROUND: Intramuscular epinephrine is the first line drug in the treatment of anaphylaxis. This study was to identify the appropriateness of 1 inch needle length for epinephrine prefilled syringes in children. METHODS: Children aged 1 month to 18 years were enrolled. Skin to muscle depth (STMD) and skin to bone depth (STBD) were measured using an ultrasonography at the mid-anterolateral thigh. A 1 inch needle was considered as being appropriate if the STBD was more than 1 inch and the STMD was less than 1 inch...
September 17, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28938838/the-effectiveness-of-newly-developed-written-asthma-action-plan-in-improvement-of-asthma-outcome-in-children
#6
Kingthong Lakupoch, Wiparat Manuyakorn, Aroonwan Preutthipan, Harutai Kamalaporn
BACKGROUND: Providing asthma education about controller medication use and appropriate management of asthma exacerbation are the keys to improving the disease outcome. Many asthma guidelines recommend that physicians provide written asthma action plan (WAAP) to all of their asthmatic patients. However, the benefit of WAAP is unclear. Thus, we have created a new WAAP which is simplified in Thai and more user friendly. OBJECTIVE: To determine the effectiveness of the newly developed asthma action plan in management of children with asthma...
September 17, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28938837/pollen-food-allergy-syndrome-in-turkey-clinical-characteristics-and-evaluation-of-its-association-with-skin-test-reactivity-to-pollens
#7
Seςil Kepil Özdemir, Selcan Özgüςlü
BACKGROUND: There is limited data regarding pollen food allergy syndrome (PFAS) in Turkey. OBJECTIVES: To investigate the clinical characteristics and possible risk factors of PFAS in Turkey, and to evaluate if there was an association between skin test reactivity to pollens and presence of PFAS. METHODS: A total of 254 consecutive adult patients with pollen sensitivity were prospectively recruited. Patients were interviewed with a questionnaire including a list of pollen-associated foods...
September 17, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/27996292/activation-of-dengue-virus-specific-t-cells-modulates-vascular-endothelial-growth-factor-receptor-2-expression
#8
Jittraporn Rattanamahaphoom, Pornsawan Leaungwutiwong, Kriengsak Limkittikul, Nathamon Kosoltanapiwat, Anon Srikaitkhachorn
BACKGROUND: The pathogenic mechanisms underlying the increased vascular permeability in dengue hemorrhagic fever (DHF) are not well understood. Enhanced cellular immune activation, especially activation of serotype-cross reactive T cells, has been implicated in plasma leakage in DHF. Changes in several biological markers and mediators including cytokines, chemokines, angiogenic factors and their receptors have been shown to correlate with disease severity. A decline in plasma levels of a soluble form of vascular endothelial growth factor receptor 2 (VEGFR2), a receptor of vascular endothelial growth factor (VEGF), has been associated with plasma leakage in dengue patients...
September 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28802032/deciphering-critical-amino-acid-residues-to-modify-and-enhance-the-binding-affinity-of-ankyrin-scaffold-specific-to-capsid-protein-of-human-immunodeficiency-virus-type-1
#9
Somphot Saoin, Tanchanok Wisitponchai, Kannaporn Intachai, Koollawat Chupradit, Sutpirat Moonmuang, Sawitree Nangola, Kuntida Kitidee, Kanda Fanhchaksai, Vannajan Sanghiran Lee, Saw-See Hong, Pierre Boulanger, Phimonphan Chuankhayan, Chun-Jung Chen, Chatchai Tayapiwatana
BACKGROUND: AnkGAG1D4 is an artificial ankyrin repeat protein which recognizes the capsid protein (CA) of the human immunodeficiency virus type 1 (HIV-1) and exhibits the intracellular antiviral activity on the viral assembly process. Improving the binding affinity of AnkGAG1D4 would potentially enhance the AnkGAG1D4-mediated antiviral activity. OBJECTIVE: To augment the affinity of AnkGAG1D4 scaffold towards its CA target, through computational predictions and experimental designs...
August 8, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28802031/quality-of-life-among-caregivers-and-growth-in-children-with-parent-reported-food-allergy
#10
Tanya Kajornrattana, Pasuree Sangsupawanich, Araya Yuenyongviwat
BACKGROUND: Some caregivers who believe their children have food allergy avoid feeding certain foods to their children without proper allergy tests. Such actions made without a proper diagnosis can negatively impact the child's health and impose an unnecessary burden on the caregivers. OBJECTIVE: This study aimed to evaluate the caregiver quality of life (QoL) and growth in children with a parent-reported food allergy. METHODS: An observational cross-sectional study was performed in 200 children younger than five years who had a parent-reported food allergy...
August 8, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28802030/solenopsis-geminata-tropical-fire-ant-anaphylaxis-among-thai-patients-its-allergens-and-specific-ige-reactivity
#11
Rutcharin Potiwat, Sasipa Tanyaratsrisakul, Santi Maneewatchararangsri, Wiparat Manuyakorn, Ticha Rerkpattanapipat, Yudthana Samung, Chukiat Sirivichayakul, Wanpen Chaicumpa, Raweerat Sitcharungsi
BACKGROUND: Specific IgE against Solenopsis invicta (imported fire ant) remains the current diagnostic tool for allergy to ants worldwide. However, S. invicta may not be the only cause of ant anaphylaxis in Thai patients. OBJECTIVE: To characterize ant species causing anaphylaxis in Thai patients and to test allergenic reactivity to whole body extracts (WBE) of S. geminata (tropical fire ants) in patients with evidence of IgE-mediated ant anaphylaxis. METHODS: Thirty-two patients with ant anaphylaxis were identified...
August 8, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28802029/immediate-hypersensitivity-reaction-to-ketamine-in-children-with-history-of-atopic-disease
#12
Seunghee Ki, Sehun Lim, Myoung-Hun Kim, Younghan Kim
Many investigators have demonstrated that a large number of patients who experience anaphylaxis during anesthesia have a history of atopic disease or allergy to a specific substance. Here, we review a hypersensitivity reaction to ketamine in a nine-year-old child with a history of atopic disease.
August 8, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28802028/h5n1-ns-genomic-segment-distinctly-governs-the-influenza-virus-infectivity-and-cytokine-induction-in-monocytic-cells
#13
Prem Prasad Lamichhane, Kobporn Boonnak, Don Changsom, Pirom Noisumdaeng, Kantima Sangsiriwut, Sa-Nga Pattanakitsakul, Pilaipan Puthavathana
BACKGROUND: The level of virulence of H5N1 highly pathogenic avian influenza (HPAI) virus was higher than those of the other virus subtypes. It has been suggested that the nonstructural (NS) gene might be a factor contributing to H5N1 HPAI virulence. OBJECTIVES: To determine the efficiency of the NS genomic segment of H5N1 HPAI virus on governing viral infectivity and cytokine induction in monocytic cells compared to other virus strain/subtypes. METHODS: By reverse genetics, five reassortant influenza viruses carrying the NS genomic segment derived from seasonal influenza A(H1N1), 2009 pandemic A(H1N1), A(H3N2) or H5N1 HPAI virus in the backbone of A/Puerto Rico/8/34 H1N1 (PR8) virus were constructed together with the reassorted PR8 virus control, i...
August 8, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28802027/performance-evaluation-of-the-bioneer-accupower%C3%A2-hiv-1-quantitative-rt-pcr-kit-comparison-with-the-roche-cobas%C3%A2-ampliprep-cobas-taqman%C3%A2-hiv-1-test-ver-2-0-for-quantification-of-hiv-1-viral-load-in-indonesia
#14
Agus Susanto Kosasih, Christine Sugiarto, Hubertus Hosti Hayuanta, Runingsih Juhaendi, Lyana Setiawan
BACKGROUND: Measurement of viral load in human immunodeficiency virus type 1 (HIV-1) infected patients is essential for the establishment of a therapeutic strategy. Several assays based on qPCR are available for the measurement of viral load; they differ in sample volume, technology applied, target gene, sensitivity and dynamic range. The Bioneer AccuPower® HIV-1 Quantitative RT-PCR is a novel commercial kit that has not been evaluated for its performance. OBJECTIVE: This study aimed to evaluate the performance of the Bioneer AccuPower® HIV-1 Quantitative RT-PCR kit...
August 8, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28802026/reversible-immune-abnormality-and-regulatory-t-cells-in-offspring-of-der-p-1-exposed-female-mice
#15
Lu Tan, Zezhang Tao, Yonggang Kong, Yu Xu
BACKGROUND: Maternal allergic diseases have an important influence on the origin of allergic rhinitis (AR) in offspring, but the mechanism and the duration of the maternal effect are unknown. Previous researches prompted the important roles of Tregs and Foxp3 DNA methylation in the development of allergic diseases. OBJECTIVE: To investigate the immune state and Tregs in the offspring of Der p 1-exposed female mice. METHOD: BALB/c female mice were exposed to Der p1 to construct the mouse AR model, then mated with normal male mice...
August 8, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28577524/childhood-asthma-control-in-japan-a-nationwide-cross-sectional-web-based-survey
#16
Koichi Yoshida, Mari Sasaki, Yuichi Adachi, Toshiko Itazawa, Hiroshi Odajima, Hirohisa Saito, Akira Akasawa
BACKGROUND: Recent surveys have shown that many patients with asthma experience uncontrolled symptoms and decreased quality of life due to their disease. However, few large population-based studies have evaluated asthma control in Japanese children. OBJECTIVE: To show the reality of asthma control and the pattern of asthma controller medication use among Japanese children. METHODS: In 2012, a web-based survey was conducted to identify children aged 6 to 11 years with asthma in Japan...
June 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28577523/quantification-of-fel-d-1-in-house-dust-samples-of-cat-allergic-patients-by-using-monoclonal-antibody-specific-to-a-novel-ige-binding-epitope
#17
Natt Tasaniyananda, Anchalee Tungtrongchitr, Watee Seesuay, Yuwaporn Sakolvaree, Pisinee Aiumurai, Nitaya Indrawattana, Wanpen Chaicumpa, Nitat Sookrung
BACKGROUND: Avoidance of allergen exposure is an effective measure for preventing naÏve and allergic individuals from sensitization (primary intervention) and disease aggravation (secondary intervention), respectively. Regular monitoring of the allergens in the environment is required for the effective intervention. Thus, there is a need for cost-effective test kits for environmental allergen quantifications. OBJECTIVE: To invent a test kit for quantification of cat major allergen, Fel d 1...
June 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28577522/rosai-dorfman-disease-with-features-of-igg4-related-disease-in-the-breast-cases-report-and-literature-review
#18
Mei Liu, Xiru Li, Ying Li, Zhuo Wang, Liuquan Cheng, Xin Song, Yun Wu
BACKGROUND: A proportion of cases of Rosai-Dorfman disease exhibit some histological features consistent with IgG4-related disease (IgG4RD). Several investigators have discussed whether Rosai-Dorfman disease belongs to the spectrum of IgG4RD or is concurrent with it by coincidence. OBJECTIVE: To elucidate the relationship between the two diseases, we report key features, including IgG4 and amyloid levels, of four cases of Rosai-Dorfman disease in the breast. METHODS: The histological features of the four cases were analyzed and the numbers of IgG4+ plasma cells and IgG4/IgG ratios were evaluated...
June 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28577521/seven-chronic-granulomatous-disease-cases-in-a-single-center-experience-and-a-review-of-the-literature
#19
Şeyhan Kutluğ, Gülnar Şensoy, Asuman Birinci, Berkay Saraymen, Mustafa Yavuz Köker, Alişan YΙldΙran
BACKGROUND: Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by defects in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase enzyme system. This disease causes the disordered functioning of phagocytic cells. It is characterized by life-threatening and/or recurrent infections by bacteria and fungi. CGD has one X-linked recessive subtype (X-CGD) and four autosomal recessive subtypes (AR-CGD), and the differential diagnosis is important in such chronic inflammatory disorders...
June 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28577520/duration-of-neutralizing-antibody-persisting-in-thai-individuals-after-childhood-vaccination-against-smallpox
#20
Kannikar Kwanchum, Silawun Ampol, Anchalee Thongput, Navin Horthongkham, Suthiphol Udomphunthurak, Sontana Siritantikorn, Wannee Kantakamalakul
BACKGROUND: Although smallpox was completely eliminated by 1980, it remains possible that variola virus could be intentionally released in an act of bioterrorism. Thus, several studies have been performed to detect antibody levels after smallpox vaccination of the current population in various countries to indicate the duration of maintenance of immunological memory. Our study endeavored to investigate the level of neutralizing (Nt) antibody responses of Thai individuals who had been immunized with smallpox vaccine during childhood...
June 1, 2017: Asian Pacific Journal of Allergy and Immunology
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