Ramkumar Aishworiya, Ye Eun Tak, Matthew Dominic Ponzini, Hazel Maridith Barlahan Biag, Maria Jimena Salcedo-Arellano, Kyoungmi Kim, Flora Tassone, Andrea Schneider, Angela John Thurman, Leonard Abbeduto, David Hessl, Jamie Leah Randol, Francois V Bolduc, Sarah Lippe, Paul Hagerman, Randi Hagerman
This study aimed to determine the association between severity of autism spectrum disorder (ASD) and cognitive, behavioral, and molecular measures in individuals with fragile X syndrome (FXS). Study inclusion criteria included individuals with FXS and (1) age 6-40 years, (2) full-scale IQ < 84, and (3) language ≥3-word phrases. ASD symptom severity was determined by Autism Diagnostic Observation Schedule-2 (ADOS-2). Other measures identified non-verbal IQ, adaptive skills, and aberrant behaviors...
September 19, 2023: International Journal of Developmental Neuroscience