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Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism

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https://www.readbyqxmd.com/read/28200067/sensation-seeking-and-adolescent-alcohol-use-exploring-the-mediating-role-of-unstructured-socializing-with-peers
#1
Sharon Sznitman, Batya Engel-Yeger
No abstract text is available yet for this article.
February 15, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28200025/preliminary-evaluation-of-the-niaaa-aap-brief-alcohol-use-screener
#2
Alan Meca, Jonathan G Tubman, Timothy Regan, Diane D Zheng, Rhoda Moise, Tae Kyoung Lee, Mary H Soares, Maria R Velazquez, Andrew Egbert, Seth J Schwartz
No abstract text is available yet for this article.
February 15, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28158458/price-elasticity-of-alcohol-demand-in-india
#3
Santosh Kumar
No abstract text is available yet for this article.
February 2, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28158652/acute-pancreatitis-impact-of-alcohol-consumption-and-seasonal-factors
#4
Sara Bertilsson, Anders Håkansson, Evangelos Kalaitzakis
No abstract text is available yet for this article.
January 31, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28130205/ethnic-variations-in-liver-and-alcohol-related-disease-hospitalisations-and-mortality-the-scottish-health-and-ethnicity-linkage-study
#5
Neeraj Bhala, Genevieve Cézard, Hester J T Ward, Narinder Bansal, Raj Bhopal
No abstract text is available yet for this article.
January 27, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28126716/joint-effects-of-the-epigenetic-alteration-of-neurotrophins-and-cytokine-signaling-a-possible-exploratory-model-of-affective-symptoms-in-alcohol-dependent-patients
#6
Annemarie Heberlein, Rilana Schuster, Alexandra Kleimann, Adrian Groh, Andreas Kordon, Birgitt Opfermann, Ralf Lichtinghagen, Michael Gröschl, Johannes Kornhuber, Stefan Bleich, Helge Frieling, Thomas Hillemacher
AIMS: Neurotrophins have been linked to the symptomatology of alcohol dependence. We aimed to investigate a possible association between the methylation of the promoters of both neurotrophins, the serum levels of the cytokines and core symptoms of alcohol dependence as withdrawal severity and anxiety. METHODS: In this study we investigated a possible association between alterations in the methylation of the BDNF IV/NGF I gene promoter and the cytokines tumor necrosis factor α (TNF-α) and interleukin-6 (IL-6) in 55 male alcohol-dependent patients...
January 26, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28171880/corrigendum-ethnic-variations-in-liver-and-alcohol-related-disease-hospitalisations-and-mortality-the-scottish-health-and-ethnicity-linkage-study
#7
Neeraj Bhala, Genevieve Cézard, Hester J T Ward, Narinder Bansal, Raj Bhopal
No abstract text is available yet for this article.
January 25, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28119414/alcohol-consumption-and-binge-drinking-in-young-men-as-predictors-of-body-composition-changes-during-military-service
#8
Maria P Hagnäs, Jari Jokelainen, Henna Cederberg-Tamminen, Solja Niemelä, Ilona Mikkola, Pirjo Härkönen, Ulla Rajala, Sirkka Keinänen-Kiukaanniemi
AIMS: To evaluate the influences of alcohol consumption frequency and binge drinking on changes in the body composition, lifestyle habits and physical fitness of healthy young men during military service. METHODS: A population-based study of men performing their military service in the Sodankylä Jaeger Brigade, Finland in 2005. Body composition, fitness and lifestyle habits were evaluated at baseline and 6-12 months follow-up. Alcohol consumption frequency and binge drinking were categorized as: 'not at all', 'at least once a month' and 'at least once a week'...
January 24, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28119413/promoter-polymorphism-rs886205-genotype-interacts-with-dna-methylation-of-the-aldh2-regulatory-region-in-alcohol-dependence
#9
Hansi Pathak, Helge Frieling, Stefan Bleich, Alexander Glahn, Annemarie Heberlein, Mani Haschemi Nassab, Thomas Hillemacher, Alexandra Burkert, Mathias Rhein
AIMS: Aldehyde dehydrogenase 2 (ALDH2) protects cells from ethanol toxicity by metabolizing acetaldehyde. We studied the single nucleotide polymorphism (SNP) rs886205s located between a negative and a positive regulating promoter element in the ALDH2 gene. The negative regulatory region was already associated with differential DNA methylation in the two allele variations of rs886205 SNP. Another CpG island, in the positive regulatory region of the ALDH2 promoter, extends through the SNP rs886205 and a nuclear receptor response element...
January 24, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28119412/typology-and-dynamics-of-heavier-drinking-styles-in-great-britain-1978-2010
#10
Robin C Purshouse, Alan Brennan, Daniel Moyo, James Nicholls, Paul Norman
AIMS: To identify a typology of heavier drinking styles in Great Britain and to identify socio-demographic trends in the typology over the period 1978-2010. METHODS: We applied multiple correspondence analysis and agglomerative hierarchical clustering to beverage-specific quantity-frequency measures of alcohol consumption in the repeated cross-sectional General Lifestyle Survey of Great Britain, 1978-2010. The cluster analysis focuses on the 60,043 adult respondents over this period reporting average drinking levels above the UK Government guidelines...
January 24, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28069599/response-to-dr-holmes-and-dr-angus
#11
LETTER
Kari Poikolainen
No abstract text is available yet for this article.
January 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28069598/a-randomized-controlled-trial-of-brief-intervention-by-interactive-voice-response
#12
Gail L Rose, Gary J Badger, Joan M Skelly, Charles D MacLean, Tonya A Ferraro, John E Helzer
AIMS: To determine the effect of an Interactive Voice Response (IVR) brief intervention (BI) to reduce alcohol consumption among adults seeking primary care. METHODS: Patients (N = 1855) with unhealthy drinking were recruited from eight academic internal medicine and family medicine clinics and randomized to IVR-BI (n = 938) versus No IVR-BI control (n = 917). Daily alcohol consumption was assessed at baseline, 3- and 6-months using the Timeline Followback. RESULTS: The IVR-BI was completed by 95% of the 938 patients randomized to that condition, and 62% of them indicated a willingness to consider a change in their drinking...
January 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28069597/chronic-binge-alcohol-induced-dysregulation-of-mitochondrial-related-genes-in-skeletal-muscle-of-simian-immunodeficiency-virus-infected-rhesus-macaques-at-end-stage-disease
#13
Anthony A Duplanty, Liz Simon, Patricia E Molina
AIMS: Alcohol use disorders are more prevalent in HIV patients than the general population. Both chronic alcohol consumption and HIV infection have been linked to mitochondrial dysregulation; and this is considered an important mechanism in the pathogenesis of muscle myopathy. This study investigated if chronic binge alcohol (CBA) administration impairs the expression of genes involved in mitochondrial homeostasis in SIV-infected macaques. METHODS: Male rhesus macaques were administered daily CBA (to achieve peak blood alcohol concentrations of 50-60 mM within 2 h after start of infusion) or sucrose (SUC) intragastrically 3 months prior to intravenous SIVmac251 inoculation and continued until macaques met criteria for end-stage disease...
January 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28069596/a-response-to-two-papers-critiquing-the-total-consumption-model-by-kari-poikolainen
#14
LETTER
John Holmes, Colin Angus
No abstract text is available yet for this article.
January 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28064151/supervised-disulfiram-s-superior-effectiveness-in-alcoholism-treatment-ethical-methodological-and-psychological-aspects
#15
REVIEW
Colin Brewer, Emmanuel Streel, Marilyn Skinner
Disulfiram (DSF) causes the ALDH-mediated deterrence of alcohol consumption. We review recent meta-analyses showing the superior effectiveness of supervised disulfiram (SD) in alcoholism treatment compared with oral naltrexone or acamprosate (ACP). The success of SD is also consistent with the almost complete absence of alcoholism in Japanese homozygotes for 'inefficient' ALDH. However, SD is an underused treatment and some clinicians have ethical objections to DSF. We examine these objections and argue that they are based on a misunderstanding of how DSF works...
January 7, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28052857/more-drinking-more-problems-stable-association-between-alcohol-consumption-and-harm-among-swedish-youth-1995-2012
#16
Siri Thor, Jonas Raninen, Jonas Landberg
AIMS: Alcohol consumption among Swedish youth increased during the 1990s. In the following decade, levels declined coinciding with a reduction in the prevalence of self-reported alcohol-related harm. We examine how the trend in self-reported alcohol-related problems among young Swedish alcohol consumers has followed the trend in alcohol consumption during 1995-2012, and test whether the strength of the association between self-reported alcohol consumption and alcohol-related problems within individuals is inversely proportional to the overall level of consumption among youth...
January 4, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28043969/the-role-of-nfkb-in-drug-addiction-beyond-inflammation
#17
REVIEW
S E Nennig, J R Schank
AIMS: Nuclear factor kappa light chain enhancer of activated B cells (NFkB) is a ubiquitous transcription factor well known for its role in the innate immune response. As such, NFkB is a transcriptional activator of inflammatory mediators such as cytokines. It has recently been demonstrated that alcohol and other drugs of abuse can induce NFkB activity and cytokine expression in the brain. A number of reviews have been published highlighting this effect of alcohol, and have linked increased NFkB function to neuroimmune-stimulated toxicity...
January 1, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28007738/malondialdehyde-as-a-prognostic-factor-in-alcoholic-hepatitis
#18
Onán Pérez-Hernández, Emilio González-Reimers, Geraldine Quintero-Platt, Pedro Abreu-González, María José de la Vega-Prieto, María José Sánchez-Pérez, Candelaria Martín-González, Antonio Martínez-Riera, Francisco Santolaria-Fernández
AIMS: Alcoholic hepatitis is a severe complication of alcoholism, associated with high short-term mortality. Although pathogenesis remains obscure, it is generally accepted that lipopolysaccharide-induced cytokine secretion with further generation of reactive oxygen species (ROS) play outstanding roles. Prognosis is uncertain, and the usually employed prognostic scores do not include variables related to ROS generation.Therefore, this study was performed to assess short-term prognostic value of cytokines, nutritional status, different scores [Maddrey, model for end-stage liver disease (MELD), albumin, bilirubin, INR, creatinine index (ABIC), Lille, Glasgow, MELD-Na, Child-Pugh] and malondialdehyde (MDA, as an indicator of lipid peroxidation) at admission and after 1 week, among patients affected by severe acute alcoholic hepatitis (Maddrey index >32)...
December 21, 2016: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28003246/erratum-alcohol-and-alzheimer-s-disease-does-alcohol-dependence-contribute-to-beta-amyloid-deposition-neuroinflammation-and-neurodegeneration-in-alzheimer-s-disease
#19
Ashwin Venkataraman, Nicola Kalk, Gavin Sewell, Craig W Ritchie, Anne Lingford-Hughes
No abstract text is available yet for this article.
December 20, 2016: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28003245/impulsivity-moderates-subjective-responses-to-alcohol-in-alcohol-dependent-individuals
#20
Jonathan G Westman, Spencer Bujarski, Lara A Ray
AIMS: Studies of social drinkers indicate that subjective response (SR) to alcohol and impulsivity are risk factors for the development of alcohol use disorder which may be related. It is unclear, however, whether there are significant relationships between SR and impulsivity among individuals with alcohol dependence. Using data from an intravenous (IV) alcohol challenge study, the present study is the first to explore the relationship between impulsivity and SR during alcohol administration among alcohol-dependent individuals...
December 20, 2016: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
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