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Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism

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https://www.readbyqxmd.com/read/28541449/barriers-to-alcohol-screening-among-hypertensive-patients-and-the-role-of-stigma-lessons-for-the-implementation-of-screening-and-brief-interventions-in-european-primary-care-settings
#1
Franz Hanschmidt, Jakob Manthey, Ludwig Kraus, Emanuele Scafato, Antoni Gual, Carsten Grimm, Jürgen Rehm
Aims: 1. To quantify barriers to alcohol screening among hypertensive patients reported by primary healthcare professionals. 2. To examine whether education and screening frequency measures are associated with stigma-related barriers. Methods: A web survey was conducted among 3081 primary healthcare professionals from France, Germany, Italy, Spain and the UK. Participants were asked about perceived barriers to alcohol screening as free-text response. The replies were independently categorized by two raters...
May 25, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28525555/a-randomized-placebo-controlled-study-of-high-dose-baclofen-in-alcohol-dependent-patients-the-alpadir-study
#2
Michel Reynaud, Henri-Jean Aubin, Francoise Trinquet, Benjamin Zakine, Corinne Dano, Maurice Dematteis, Benoit Trojak, Francois Paille, Michel Detilleux
Aims: Alcohol dependence is a major public health issue with a need for new pharmacological treatments. The ALPADIR study assessed the efficacy and safety of baclofen at the target dose of 180 mg/day for the maintenance of abstinence and the reduction in alcohol consumption in alcohol-dependent patients. Methods: Three hundred and twenty adult patients (158 baclofen and 162 placebo) were randomized after alcohol detoxification. After a 7-week titration, the maintenance dose was provided for 17 weeks, then progressively decreased over 2 weeks before stopping...
May 19, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28525540/alcohol-consumption-and-common-carotid-intima-media-thickness-the-use-imt-study
#3
Annie R Britton, Diederick E Grobbee, Hester M den Ruijter, Todd J Anderson, Moise Desvarieux, Gunnar Engström, Greg W Evans, Bo Hedblad, Jussi Kauhanen, Sudhir Kurl, Eva M Lonn, Ellisiv B Mathiesen, Joseph F Polak, Jacqueline F Price, Christopher M Rembold, Maria Rosvall, Tatjana Rundek, Jukka T Salonen, Coen Stehouwer, Tomi-Pekka Tuomainen, Michiel L Bots
Aims: Epidemiological evidence indicates a protective effect of light to moderate alcohol consumption compared to non-drinking and heavy drinking. Although several mechanisms have been suggested, the effect of alcohol on atherosclerotic changes in vessel walls is unclear. Therefore, we explored the relationship between alcohol consumption and common carotid intima media thickness, a marker of early atherosclerosis in the general population. Methods: Individual participant data from eight cohorts, involving 37,494 individuals from the USE-IMT collaboration were used...
May 19, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28525537/the-influence-of-smoking-and-smokeless-tobacco-on-the-progression-severity-and-treatment-outcome-in-alcohol-dependent-individuals
#4
Kerstin K Rauwolf, Kristina J Berglund, Ulf Berggren, Jan Balldin, Claudia Fahlke
Aims: The influence of tobacco use in alcohol-dependent individuals is not well understood, especially the role of snuffing, which is common in Northern Europe. The aim was therefore to investigate the influence of smoking and snuffing on the progression, severity and treatment outcome in alcohol-dependent individuals. The hypotheses were that concomitant tobacco use (i.e. smoking or snuffing) would enhance the progression and severity of alcohol dependence and be less beneficial for treatment outcome, relative to tobacco non-users...
May 19, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28498886/risky-drinkers-underestimate-their-own-alcohol-consumption
#5
Antoni Gual, José Ángel Arbesú, José Zarco, María de Las Mercedes Balcells-Oliveró, Hugo López-Pelayo, Laia Miquel, Julio Bobes
No abstract text is available yet for this article.
May 11, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28482064/gut-liver-axis-and-sterile-signals-in-the-development-of-alcoholic-liver-disease
#6
Gyongyi Szabo, Jan Petrasek
Background: Innate immunity plays a critical role in the development of alcohol-induced liver inflammation. Understanding the inter-relationship of signals from within and outside of the liver that trigger liver inflammation is pivotal for development of novel therapeutic targets of alcoholic liver disease (ALD). Aim: The aim of this paper is to review recent advances in the field of alcohol-induced liver inflammation. Methods: A detailed literature review was performed using the PubMed database published between January 1980 and December 2016...
May 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28482009/the-microbiota-the-gut-and-the-brain-in-eating-and-alcohol-use-disorders-a-m%C3%A3-nage-%C3%A3-trois
#7
Jamie E Temko, Sofia Bouhlal, Mehdi Farokhnia, Mary R Lee, John F Cryan, Lorenzo Leggio
Aims: Accumulating evidence for the influence of the gut microbiota on the bidirectional communication along the gut-brain axis suggests a role of the gut microbiota in eating disorders (EDs) and alcohol and substance use disorders. The potential influence of altered gut microbiota (dysbiosis) on behaviors associated with such disorders may have implications for developing therapeutic interventions. Methods: A systematic review of preclinical and clinical studies evaluating the gut microbiota, EDs and alcohol and substance use disorders was conducted using MEDLINE, Embase and Web of Science databases with the objective being to examine the role of the gut microbiota in behavioral correlates of these disorders...
May 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28481975/the-leu72met-polymorphism-of-the-prepro-ghrelin-gene-is-associated-with-alcohol-consumption-and-subjective-responses-to-alcohol-preliminary-findings
#8
Petra Suchankova, Jia Yan, Melanie L Schwandt, Bethany L Stangl, Elisabet Jerlhag, Jörgen A Engel, Colin A Hodgkinson, Vijay A Ramchandani, Lorenzo Leggio
Aims: The orexigenic peptide ghrelin may enhance the incentive value of food-, drug- and alcohol-related rewards. Consistent with preclinical findings, human studies indicate a role of ghrelin in alcohol use disorders (AUD). In the present study an a priori hypothesis-driven analysis was conducted to investigate whether a Leu72Met missense polymorphism (rs696217) in the prepro-ghrelin gene (GHRL), is associated with AUD, alcohol consumption and subjective responses to alcohol. Method: Association analysis was performed using the National Institute on Alcohol Abuse and Alcoholism (NIAAA) clinical sample, comprising AUD individuals and controls (N = 1127)...
May 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28481974/ghrelin-is-supressed-by-intravenous-alcohol-and-is-related-to-stimulant-and-sedative-effects-of-alcohol
#9
Elizabeth Ralevski, Tamas L Horvath, Marya Shanabrough, Ryan Hayden, Jenelle Newcomb, Ismene Petrakis
Aims: Evidence indicates that feeding-related peptides, such as ghrelin, have a role in the rewarding properties of addictive substances like alcohol. Oral alcohol administration significantly suppresses ghrelin. This study was designed to evaluate the effects of two doses of alcohol on ghrelin and examine if ghrelin levels predict the subjective effects of alcohol. Methods: Healthy social drinkers (N = 20) participated in three, randomly assigned, and counterbalanced laboratory sessions...
May 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28481972/age-of-onset-current-use-of-alcohol-tobacco-or-marijuana-and-current-polysubstance-use-among-male-and-female-mexican-students
#10
Lee Strunin, Alejandro Díaz-Martínez, L Rosa Díaz-Martínez, Timothy Heeren, Clara Chen, Michael Winter, Seth Kuranz, Carlos A Hernández-Ávila, Héctor Fernández-Varela, Cuauhtémoc Solís-Torres
Aims: This study aimed to examine alcohol, tobacco or marijuana use onset and associations between age of onset and current use, and between age of onset and current polysubstance use among a sample of Mexican young people aged 17-20 years. Methods: Alcohol, tobacco, marijuana and other substance use were identified in a 2012 cross-sectional survey of male and female students entering first year university in Mexico City. Chi-square tests and logistic regression models examined associations between gender, age of onset, order of onset, family substance use and current polysubstance use among 22,224 students...
May 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28419179/the-intensity-of-brief-interventions-in-patients-with-acute-alcoholic-pancreatitis-should-be-increased-especially-in-young-patients-with-heavy-alcohol-consumption
#11
Jussi Nikkola, Johanna Laukkarinen, Heini Huhtala, Juhani Sand
Aims: After the first acute alcoholic pancreatitis (AAP), active repeated brief interventions (BIs) have been shown to protect against recurrent acute pancreatitis (RAP). However, in daily hospital practice the treatment of alcohol problems varies. Our aim was to study BIs performed in the clinic during AAP and whether this prevents from future RAP episodes. Methods: Data on all patients discharged between 10/2010 and 10/2012 with acute pancreatitis as the primary diagnosis were obtained from the hospital database...
April 13, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28379324/are-changes-in-alcohol-consumption-among-swedish-youth-really-occurring-in-concert-a-new-perspective-using-quantile-regression
#12
Zangin Zeebari, Andreas Lundin, Paul W Dickman, Mats Hallgren
Aims: Recent studies of youth alcohol consumption indicate a collective downward drinking trend at all levels of consumption, i.e. reductions occurring 'in concert'. We re-examine the collectivity of drinking theory by applying quantile regression methods to the analysis and interpretation of Swedish youth alcohol consumption. Method: Changes in youth alcohol consumption between 2000 and 2014 were assessed using a school-based survey conducted in Stockholm (n = 86,402)...
April 4, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28379321/use-of-psychoactive-medication-in-short-and-long-term-abstainers-from-alcohol
#13
Bertrand Nalpas, Pascal Perney
Aim: To document the use of prescribed psychoactive medicines in France in patients recovering from alcohol use disorders (AUDs). Method: Survey among short- and long-term abstainers attending groups of French self-help associations for AUDs, recording socio-demographic profile, duration of abstinence, prescription of psychoactive medication and attitudes towards that, and whether or not in medical or psychological follow-up for AUD. Result: Five hundred seventy-five abstainers participated...
April 4, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28379312/associations-between-personality-and-drinking-motives-among-abstinent-adult-alcoholic-men-and-women
#14
Susan Mosher Ruiz, Marlene Oscar-Berman, Maaria I Kemppainen, Mary M Valmas, Kayle S Sawyer
Aims: Men and women differ in personality characteristics and may be motivated to use alcohol for different reasons. The goals of the present study were to characterize personality and drinking motives by gender and alcoholism status in adults, and to determine how alcoholism history and gender are related to the associations between personality traits and drinking motivation. Methods: Personality characteristics were assessed with the Eysenck Personality Questionnaire, which includes Extraversion, Neuroticism, Psychoticism and Lie (Social Conforming) scales...
April 4, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28371801/preliminary-evaluation-of-the-niaaa-aap-brief-alcohol-use-screener
#15
Alan Meca, Jonathan G Tubman, Timothy Regan, Diane D Zheng, Rhoda Moise, Tae Kyoung Lee, Mary H Soares, Maria R Velazquez, Andrew Egbert, Seth J Schwartz
No abstract text is available yet for this article.
March 29, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28371897/screening-for-at-risk-alcohol-consumption-in-primary-care-a-randomized-evaluation-of-screening-approaches
#16
Simon Coulton, Veronica Dale, Paolo Deluca, Eilish Gilvarry, Christine Godfrey, Eileen Kaner, Ruth McGovern, Dorothy Newbury-Birch, Robert Patton, Steve Parrott, Katherine Perryman, Thomas Phillips, Jonathan Shepherd, Colin Drummond
Aims: The aim of the study was to explore the relative efficiency and effectiveness of targeted versus universal screening for at-risk alcohol use in a primary care population in the UK. Methods: The study was a randomized evaluation of screening approach (targeted versus universal) for consecutive attendees at primary care aged 18 years or more. Targeted screening involved screening any patient attending with one of the targeted presentations, conditions associated with excessive alcohol consumption: mental health, gastrointestinal, hypertension, minor injuries or a new patient registration...
March 24, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28371811/feasibility-of-studying-a-brief-intervention-to-help-chinese-villagers-with-problem-alcohol-use-after-an-earthquake
#17
Ruan Xiaolu, Wang Wenwen, Robert Ali, Li Xu, Wen Hong, Zhao Min, Du Jiang
Aim: To evaluate the feasibility of conducting a study of structured brief intervention (BI) for reducing problem alcohol use among individuals who experienced earthquake. Methods: Following the Wenchuan earthquake, 1336 clients from 18 local hospitals were invited to complete the Alcohol Use Disorders Identification Test (AUDIT). Of those, 239 individuals (AUDIT score of greater than or equal to 7) were included in the study. The participants from intervention village hospitals who were assigned to the BI group (n = 118) received a structured BI lasting 15-30 min plus general health education...
March 22, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28340213/effects-of-alcohol-dependence-severity-on-neural-correlates-of-delay-discounting
#18
Aaron C Lim, Anita Cservenka, Lara A Ray
Aims: The current study examines the relationship between alcohol dependence severity and delay discounting neural activation. Methods: Participants (N = 17; 6 female) completed measures of alcohol use and severity and a functional magnetic resonance imaging version of a delay discounting task. Results: Alcohol dependence severity was negatively associated with activation in superior frontal gyrus during impulsive relative to delayed decisions, and positively associated with activation in paracingulate gyrus and frontal pole in delayed relative to impulsive decisions...
March 18, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28340112/long-term-mortality-of-patients-with-an-alcohol-related-wernicke-korsakoff-syndrome
#19
Arantza Sanvisens, Paola Zuluaga, Daniel Fuster, Inmaculada Rivas, Jordi Tor, Miguel Marcos, Antonio J Chamorro, Roberto Muga
Aims: To characterize a series of contemporary patients with alcohol-related Wernicke's encephalopathy (WE) or Korsakoff's syndrome (KS) and to update the current prognosis of disease. Methods: Retrospective and prospective study of patients diagnosed with an alcohol-related WE or KS between 2002 and 2011 in a tertiary hospital. Socio-demographic, alcohol use characteristics, signs and symptoms, co-morbidity and blood parameters were obtained at admission. Patients were followed up until 2013 and causes of death were ascertained through the review of charts...
March 10, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28340031/one-year-clinical-correlates-of-etg-positive-urine-screening-in-alcohol-dependent-patients-a-survival-analysis
#20
Pablo Barrio, Silvia Mondon, Lídia Teixidor, Lluisa Ortega, Eduard Vieta, Antoni Gual
Aims: Little evidence exists supporting the efficacy of regular alcohol urine screening (RAUS) in the management of alcohol dependence, despite recent improvements in urine biomarkers. In this study, we aimed at investigating 1 year, differential clinical correlates between a positive and a negative baseline urine ethyl glucuronide (EtG) screening. Methods: Alcohol-dependent outpatients participating in a previous cross-sectional study where EtG and ethanol diagnostic performances were compared in a double blind design were included...
March 10, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
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