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Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism

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https://www.readbyqxmd.com/read/28340213/effects-of-alcohol-dependence-severity-on-neural-correlates-of-delay-discounting
#1
Aaron C Lim, Anita Cservenka, Lara A Ray
Aims: The current study examines the relationship between alcohol dependence severity and delay discounting neural activation. Methods: Participants (N = 17; 6 female) completed measures of alcohol use and severity and a functional magnetic resonance imaging version of a delay discounting task. Results: Alcohol dependence severity was negatively associated with activation in superior frontal gyrus during impulsive relative to delayed decisions, and positively associated with activation in paracingulate gyrus and frontal pole in delayed relative to impulsive decisions...
March 18, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28340112/long-term-mortality-of-patients-with-an-alcohol-related-wernicke-korsakoff-syndrome
#2
Arantza Sanvisens, Paola Zuluaga, Daniel Fuster, Inmaculada Rivas, Jordi Tor, Miguel Marcos, Antonio J Chamorro, Roberto Muga
Aims: To characterize a series of contemporary patients with alcohol-related Wernicke's encephalopathy (WE) or Korsakoff's syndrome (KS) and to update the current prognosis of disease. Methods: Retrospective and prospective study of patients diagnosed with an alcohol-related WE or KS between 2002 and 2011 in a tertiary hospital. Socio-demographic, alcohol use characteristics, signs and symptoms, co-morbidity and blood parameters were obtained at admission. Patients were followed up until 2013 and causes of death were ascertained through the review of charts...
March 10, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28340031/one-year-clinical-correlates-of-etg-positive-urine-screening-in-alcohol-dependent-patients-a-survival-analysis
#3
Pablo Barrio, Silvia Mondon, Lídia Teixidor, Lluisa Ortega, Eduard Vieta, Antoni Gual
Aims: Little evidence exists supporting the efficacy of regular alcohol urine screening (RAUS) in the management of alcohol dependence, despite recent improvements in urine biomarkers. In this study, we aimed at investigating 1 year, differential clinical correlates between a positive and a negative baseline urine ethyl glucuronide (EtG) screening. Methods: Alcohol-dependent outpatients participating in a previous cross-sectional study where EtG and ethanol diagnostic performances were compared in a double blind design were included...
March 10, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28339865/myrddin-evans-a-gentleman-and-a-founder-of-the-medical-council-on-alcohol-mca-and-its-journal
#4
Abdulla A-B Badawy, Boris Tabakoff
No abstract text is available yet for this article.
March 1, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28339858/relationship-between-emotional-processing-drinking-severity-and-relapse-in-adults-treated-for-alcohol-dependence-in-poland
#5
Maciej Kopera, Andrzej Jakubczyk, Hubert Suszek, Jennifer M Glass, Anna Klimkiewicz, Anna Wnorowska, Kirk J Brower, Marcin Wojnar
No abstract text is available yet for this article.
March 1, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28339869/alcohol-induces-cellular-senescence-and-impairs-osteogenic-potential-in-bone-marrow-derived-mesenchymal-stem-cells
#6
Xi Chen, Mao Li, Jinku Yan, Tao Liu, Guoqing Pan, Huilin Yang, Ming Pei, Fan He
Aims: Chronic and excessive alcohol consumption is a high-risk factor for osteoporosis. Bone marrow-derived mesenchymal stem cells (BM-MSCs) play an important role in bone formation; however, they are vulnerable to ethanol (EtOH). The purpose of this research was to investigate whether EtOH could induce premature senescence in BM-MSCs and subsequently impair their osteogenic potential. Methods: Human BM-MSCs were exposed to EtOH ranging from 10 to 250 mM. Senescence-associated β-galactosidase (SA-β-gal) activity, cell cycle distribution, cell proliferation and reactive oxygen species (ROS) were evaluated...
February 25, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28339635/the-impact-of-zonisamide-on-the-development-and-course-of-alcohol-dependence-in-rabbits-a-pharmaco-eeg-study
#7
Agata Krupa-Burtnik, Ewa Zwierzynska, Anna Kordala, Boguslawa Pietrzak
Aims: Zonisamide is a new anti-epileptic drug whose mechanism of action is associated with neurotransmission systems also involved in the pathogenesis of addiction. Recently, the role of memory processes and the hippocampus (Hp) is underlined in dependence. In our previous study, we determined that zonisamide decreases changes in hippocampal bioelectric activity induced by a single dose of ethanol. Methods: This study uses a pharmaco-EEG method to examine the impact of zonisamide on the development and course of alcohol dependence in rabbits...
February 17, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28200067/sensation-seeking-and-adolescent-alcohol-use-exploring-the-mediating-role-of-unstructured-socializing-with-peers
#8
Sharon Sznitman, Batya Engel-Yeger
No abstract text is available yet for this article.
February 15, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28200025/preliminary-evaluation-of-the-niaaa-aap-brief-alcohol-use-screener
#9
Alan Meca, Jonathan G Tubman, Timothy Regan, Diane D Zheng, Rhoda Moise, Tae Kyoung Lee, Mary H Soares, Maria R Velazquez, Andrew Egbert, Seth J Schwartz
No abstract text is available yet for this article.
February 15, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28158458/price-elasticity-of-alcohol-demand-in-india
#10
Santosh Kumar
No abstract text is available yet for this article.
February 2, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28158652/acute-pancreatitis-impact-of-alcohol-consumption-and-seasonal-factors
#11
Sara Bertilsson, Anders Håkansson, Evangelos Kalaitzakis
No abstract text is available yet for this article.
January 31, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28130205/ethnic-variations-in-liver-and-alcohol-related-disease-hospitalisations-and-mortality-the-scottish-health-and-ethnicity-linkage-study
#12
Neeraj Bhala, Genevieve Cézard, Hester J T Ward, Narinder Bansal, Raj Bhopal
No abstract text is available yet for this article.
January 27, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28126716/joint-effects-of-the-epigenetic-alteration-of-neurotrophins-and-cytokine-signaling-a-possible-exploratory-model-of-affective-symptoms-in-alcohol-dependent-patients
#13
Annemarie Heberlein, Rilana Schuster, Alexandra Kleimann, Adrian Groh, Andreas Kordon, Birgitt Opfermann, Ralf Lichtinghagen, Michael Gröschl, Johannes Kornhuber, Stefan Bleich, Helge Frieling, Thomas Hillemacher
AIMS: Neurotrophins have been linked to the symptomatology of alcohol dependence. We aimed to investigate a possible association between the methylation of the promoters of both neurotrophins, the serum levels of the cytokines and core symptoms of alcohol dependence as withdrawal severity and anxiety. METHODS: In this study we investigated a possible association between alterations in the methylation of the BDNF IV/NGF I gene promoter and the cytokines tumor necrosis factor α (TNF-α) and interleukin-6 (IL-6) in 55 male alcohol-dependent patients...
January 26, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28171880/corrigendum-ethnic-variations-in-liver-and-alcohol-related-disease-hospitalisations-and-mortality-the-scottish-health-and-ethnicity-linkage-study
#14
Neeraj Bhala, Genevieve Cézard, Hester J T Ward, Narinder Bansal, Raj Bhopal
No abstract text is available yet for this article.
January 25, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28119414/alcohol-consumption-and-binge-drinking-in-young-men-as-predictors-of-body-composition-changes-during-military-service
#15
Maria P Hagnäs, Jari Jokelainen, Henna Cederberg-Tamminen, Solja Niemelä, Ilona Mikkola, Pirjo Härkönen, Ulla Rajala, Sirkka Keinänen-Kiukaanniemi
AIMS: To evaluate the influences of alcohol consumption frequency and binge drinking on changes in the body composition, lifestyle habits and physical fitness of healthy young men during military service. METHODS: A population-based study of men performing their military service in the Sodankylä Jaeger Brigade, Finland in 2005. Body composition, fitness and lifestyle habits were evaluated at baseline and 6-12 months follow-up. Alcohol consumption frequency and binge drinking were categorized as: 'not at all', 'at least once a month' and 'at least once a week'...
January 24, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28119413/promoter-polymorphism-rs886205-genotype-interacts-with-dna-methylation-of-the-aldh2-regulatory-region-in-alcohol-dependence
#16
Hansi Pathak, Helge Frieling, Stefan Bleich, Alexander Glahn, Annemarie Heberlein, Mani Haschemi Nassab, Thomas Hillemacher, Alexandra Burkert, Mathias Rhein
AIMS: Aldehyde dehydrogenase 2 (ALDH2) protects cells from ethanol toxicity by metabolizing acetaldehyde. We studied the single nucleotide polymorphism (SNP) rs886205s located between a negative and a positive regulating promoter element in the ALDH2 gene. The negative regulatory region was already associated with differential DNA methylation in the two allele variations of rs886205 SNP. Another CpG island, in the positive regulatory region of the ALDH2 promoter, extends through the SNP rs886205 and a nuclear receptor response element...
January 24, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28119412/typology-and-dynamics-of-heavier-drinking-styles-in-great-britain-1978-2010
#17
Robin C Purshouse, Alan Brennan, Daniel Moyo, James Nicholls, Paul Norman
AIMS: To identify a typology of heavier drinking styles in Great Britain and to identify socio-demographic trends in the typology over the period 1978-2010. METHODS: We applied multiple correspondence analysis and agglomerative hierarchical clustering to beverage-specific quantity-frequency measures of alcohol consumption in the repeated cross-sectional General Lifestyle Survey of Great Britain, 1978-2010. The cluster analysis focuses on the 60,043 adult respondents over this period reporting average drinking levels above the UK Government guidelines...
January 24, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28069599/response-to-dr-holmes-and-dr-angus
#18
LETTER
Kari Poikolainen
No abstract text is available yet for this article.
January 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28069598/a-randomized-controlled-trial-of-brief-intervention-by-interactive-voice-response
#19
Gail L Rose, Gary J Badger, Joan M Skelly, Charles D MacLean, Tonya A Ferraro, John E Helzer
AIMS: To determine the effect of an Interactive Voice Response (IVR) brief intervention (BI) to reduce alcohol consumption among adults seeking primary care. METHODS: Patients (N = 1855) with unhealthy drinking were recruited from eight academic internal medicine and family medicine clinics and randomized to IVR-BI (n = 938) versus No IVR-BI control (n = 917). Daily alcohol consumption was assessed at baseline, 3- and 6-months using the Timeline Followback. RESULTS: The IVR-BI was completed by 95% of the 938 patients randomized to that condition, and 62% of them indicated a willingness to consider a change in their drinking...
January 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28069597/chronic-binge-alcohol-induced-dysregulation-of-mitochondrial-related-genes-in-skeletal-muscle-of-simian-immunodeficiency-virus-infected-rhesus-macaques-at-end-stage-disease
#20
Anthony A Duplanty, Liz Simon, Patricia E Molina
AIMS: Alcohol use disorders are more prevalent in HIV patients than the general population. Both chronic alcohol consumption and HIV infection have been linked to mitochondrial dysregulation; and this is considered an important mechanism in the pathogenesis of muscle myopathy. This study investigated if chronic binge alcohol (CBA) administration impairs the expression of genes involved in mitochondrial homeostasis in SIV-infected macaques. METHODS: Male rhesus macaques were administered daily CBA (to achieve peak blood alcohol concentrations of 50-60 mM within 2 h after start of infusion) or sucrose (SUC) intragastrically 3 months prior to intravenous SIVmac251 inoculation and continued until macaques met criteria for end-stage disease...
January 8, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
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