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Retina

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https://www.readbyqxmd.com/read/28650925/quantitative-analysis-of-the-inner-retinal-layer-thicknesses-in-age-related-macular-degeneration-using-corrected-optical-coherence-tomography-segmentation
#1
Ilkay Kilic Muftuoglu, Hema L Ramkumar, Dirk-Uwe Bartsch, Amit Meshi, Raouf Gaber, William R Freeman
PURPOSE: To characterize inner retinal damage in patients with dry age-related macular degeneration (AMD) using high-resolution spectral domain optical coherence tomography images. METHODS: Sixty eyes of 60 patients with AMD were categorized using the Age-Related Eye Disease Study (AREDS) severity scale. Spectral domain optical coherence tomography images of these patients were quantified by manually correcting the segmentation of each retinal layer, including the retinal nerve fiber layer, ganglion cell layer, and inner plexiform layer to ensure accurate delineation of layers...
June 23, 2017: Retina
https://www.readbyqxmd.com/read/28644305/management-of-in-the-bag-intraocular-lens-dislocation-into-vitreous-cavity-with-temporary-10-0-polypropylene-suture-support-and-ab-externo-scleral-fixation
#2
https://www.readbyqxmd.com/read/28644304/abnormal-retinal-reflectivity-to-short-wavelength-light-in-type-2-idiopathic-macular-telangiectasia
#3
Ferenc B Sallo, Irene Leung, Meike Zeimer, Traci E Clemons, Adam M Dubis, Marcus Fruttiger, Daniel Pauleikhoff, Emily Y Chew, Catherine Egan, Tunde Peto, Alan C Bird
PURPOSE: Macular telangiectasia Type 2 (MacTel) is a bilateral, progressive, potentially blinding retinal disease characterized by vascular and neurodegenerative signs, including an increased parafoveal reflectivity to blue light. Our aim was to investigate the relationship of this sign with other signs of macular telangiectasia Type 2 in multiple imaging modalities. METHODS: Participants were selected from the MacTel Type 2 study, based on a confirmed diagnosis and the availability of images...
June 21, 2017: Retina
https://www.readbyqxmd.com/read/28622270/dexamethasone-intravitreal-implant-for-the-treatment-of-recalcitrant-macular-edema-after-rhegmatogenous-retinal-detachment-repair
#4
Aristomenis Thanos, Bozho Todorich, Yoshihiro Yonekawa, Thanos D Papakostas, Tahsin Khundkar, Dean Eliott, Ashvani B Dass, George A Williams, Antonio Capone, Lisa J Faia, Jeremy D Wolfe, Tarek S Hassan, Alan J Ruby
PURPOSE: To investigate the efficacy of the intravitreal dexamethasone implant as the treatment for recalcitrant macular edema after successful rhegmatogenous retinal detachment repair. METHODS: A retrospective review of the medical records was performed on 17 consecutive patients (17 eyes) with recalcitrant macular edema associated with rhegmatogenous retinal detachment repair who were treated with a single or multiple injections of an intravitreal dexamethasone 0...
June 15, 2017: Retina
https://www.readbyqxmd.com/read/28622271/bubble-wiping-technique-for-clearing-the-condensation-on-intraocular-lenses
#5
Kentaro Yuda, Takamitsu Nagashima, Toshiki Shimizu, Kenji Yuda, Takahiko Hayashi
No abstract text is available yet for this article.
June 14, 2017: Retina
https://www.readbyqxmd.com/read/28614133/time-course-of-changes-in-metamorphopsia-following-intravitreal-ranibizumab-injection-for-branch-retinal-vein-occlusion
#6
Yoshimi Sugiura, Fumiki Okamoto, Shohei Morikawa, Yoshifumi Okamoto, Takahiro Hiraoka, Tetsuro Oshika
PURPOSE: To evaluate the effects of intravitreal ranibizumab injection (IVR) on metamorphopsia in patients with branch retinal vein occlusion (BRVO) and to assess the relationship between retinal microstructure and metamorphopsia. METHODS: Subjects were 39 eyes of 39 patients with branch retinal vein occlusion. The severity of metamorphopsia was quantified using the M-CHARTS before and 1, 2, 3, 4, 5, and 6 months after treatment. Based on optical coherence tomography (OCT) images, we assessed central retinal thickness (CRT) and status of the external limiting membrane (ELM) and ellipsoid zone (EZ)...
June 13, 2017: Retina
https://www.readbyqxmd.com/read/28604541/high-dose-high-frequency-aflibercept-for-recalcitrant-neovascular-age-related-macular-degeneration
#7
Qi Sheng You, Raouf Gaber, Amit Meshi, Hema L Ramkumar, Mostafa Alam, Ilkay Kilic Muftuoglu, William R Freeman
PURPOSE: To determine the efficacy of monthly (0.1 mL/4 mg) aflibercept for refractory neovascular age-related macular degeneration (wet age-related macular degeneration). METHODS: This was a retrospective interventional case series in which patients with wet age-related macular degeneration were treated with stepwise dose escalation. Nonvitrectomized patients resistant to monthly (Q4W) ranibizumab/bevacizumab were switched to 2 mg aflibercept every 8 weeks. With resistance, they were escalated to Q4W 2 mg aflibercept, then Q4W 4 mg (high dose high frequency, 4Q4W) aflibercept...
June 9, 2017: Retina
https://www.readbyqxmd.com/read/28594752/residual-vitreous-cortex-at-the-fovea-during-vitrectomy-for-primary-rhegmatogenous-retinal-detachment-repair
#8
Eun Hyung Cho, Hee Chan Ku, Won Il, Eun Koo Lee
PURPOSE: To investigate the frequency of residual cortex and the effectiveness of removal of residual cortex in the fovea during vitrectomy for primary rhegmatogenous retinal detachment repair. METHODS: We retrospectively reviewed the charts and the operative videos of the 80 patients (80 eyes) who underwent vitrectomy for repair and who were observed for more than 6 months. After triamcinolone acetonide injection, we observed residual cortex on the surface of the retina...
June 7, 2017: Retina
https://www.readbyqxmd.com/read/28613214/ex-vivo-model-for-the-characterization-and-identification-of-drywall-intraocular-foreign-bodies-on-computed-tomography
#9
Reema Syed, Sung-Hye Kim, Agustina Palacio, William R Nunery, Shlomit Schaal
BACKGROUND: The study was inspired after the authors encountered a patient with a penetrating globe injury due to drywall, who had retained intraocular drywall foreign body. Computed tomography (CT) was read as normal in this patient. Open globe injury with drywall has never been reported previously in the literature and there are no previous studies describing its radiographic features. METHODS: The case report is described in detail elsewhere. This was an experimental study...
June 6, 2017: Retina
https://www.readbyqxmd.com/read/28613213/ellipsoid-zone-mapping-and-outer-retinal-assessment-in-stargardt-disease
#10
Sruthi Arepalli, Elias I Traboulsi, Justis P Ehlers
PURPOSE: To quantify and correlate ellipsoid zone and photoreceptor outer segment changes with visual acuity in Stargardt disease. METHODS: An institutional review board-approved study of 32 eyes with Stargardt disease was performed. After spectral domain optical coherence tomography, the macular cube was exported into a novel analysis tool and volumetric assessment from the ellipsoid zone to the retinal pigment epithelium was performed. Using this information, mapping was completed with en face representation of the height between the ellipsoid zone and retinal pigment epithelium...
June 6, 2017: Retina
https://www.readbyqxmd.com/read/28574924/optical-coherence-tomography-angiography-in-retinal-vein-occlusion-correlations-between-macular-vascular-density-visual-acuity-and-peripheral-nonperfusion-area-on-fluorescein-angiography
#11
Daniel Seknazi, Florence Coscas, Alexandre Sellam, Fabien Rouimi, Gabriel Coscas, Eric H Souied, Agnès Glacet-Bernard
PURPOSE: To study correlations in patients with retinal vein occlusion between the automatically quantified macular vascular densities in the superficial and deep capillary plexus (DCP) obtained using optical coherence tomography angiography (OCTA) and the data from conventional examination, particularly visual acuity and peripheral retinal nonperfusion assessed using fluorescein angiography (FA). METHODS: Retrospective, observational study of patients with retinal vein occlusion who underwent a comprehensive ophthalmic examination including FA and OCTA using the AngioVue OCTA system version 2015...
May 31, 2017: Retina
https://www.readbyqxmd.com/read/28574923/evaluation-of-patchy-atrophy-secondary-to-high-myopia-by-semiautomated-software-for-fundus-autofluorescence-analysis
#12
Alexandra Miere, Vittorio Capuano, Rita Serra, Camille Jung, Eric Souied, Giuseppe Querques
PURPOSE: To evaluate the progression of patchy atrophy in high myopia using semiautomated software for fundus autofluorescence (FAF) analysis. METHODS: The medical records and multimodal imaging of 21 consecutive highly myopic patients with macular chorioretinal patchy atrophy (PA) were retrospectively analyzed. All patients underwent repeated fundus autofluorescence and spectral domain optical coherence tomography over at least 12 months. Color fundus photography was also performed in a subset of patients...
May 31, 2017: Retina
https://www.readbyqxmd.com/read/28570486/handheld-spectral-domain-optical-coherence-tomography-imaging-through-the-undilated-pupil-in-infants-born-preterm-or-with-hypoxic-injury-or-hydrocephalus
#13
Du Tran-Viet, Brittany M Wong, Shwetha Mangalesh, Ramiro Maldonado, C Michael Cotten, Cynthia A Toth
PURPOSE: The authors investigated feasibility of undilated handheld spectral domain optical coherence tomography (SDOCT) retinal imaging in preterm infants and children with neurologic abnormalities. METHODS: Under an institutional review board-approved protocol, the authors attempted handheld SDOCT imaging of the retina, choroid, and optic nerve in infants and young children without pupil dilation. Scans were analyzed for quality and successful capture of foveal, optic nerve, and retinal structural parameters and abnormalities...
May 29, 2017: Retina
https://www.readbyqxmd.com/read/28570485/risk-factors-for-recurrences-of-central-serous-chorioretinopathy
#14
Alexandre Matet, Alejandra Daruich, Marta Zola, Francine Behar-Cohen
PURPOSE: To describe recurrence patterns and investigate candidate risk factors for recurrences of central serous chorioretinopathy. METHODS: In 46 patients with acute central serous chorioretinopathy and follow-up >12 months after first episode resolution, parameters influencing recurrences were retrospectively evaluated using a frailty Cox proportional hazard survival model. Covariates included baseline systemic findings: age, gender, corticosteroid use, stress, shift work, sleep disorder, depression, allergy, cardiovascular risk; baseline optical coherence tomography findings: subfoveal choroidal thickness, pigment epithelial detachment pattern (regular/bump/irregular), number of subretinal hyperreflective foci at leakage site; baseline angiographic findings: fluorescein leakage intensity (intense/moderate/subtle/absent), hyperpermeability pattern on indocyanine-green angiography (focal/multifocal); and episode-related findings: duration and treatment of previous episode...
May 29, 2017: Retina
https://www.readbyqxmd.com/read/28570484/optical-coherence-tomography-angiography-features-of-choroidal-neovascularization-associated-with-choroidal-nevus
#15
Marco Pellegrini, Federico Corvi, Emil A T Say, Carol L Shields, Giovanni Staurenghi
PURPOSE: To describe the imaging features of choroidal neovascularization (CNV) associated with choroidal nevus using optical coherence tomography angiography (OCT-A) imaging. METHODS: Retrospective observational case series. Patients with CNV secondary to choroidal nevus underwent full imaging examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral domain OCT, and OCT-A. The OCT-A features were analyzed and correlated with conventional angiography findings and spectral domain OCT...
May 29, 2017: Retina
https://www.readbyqxmd.com/read/28570483/the-efficacy-of-superior-inverted-internal-limiting-membrane-flap-technique-for-the-treatment-of-full-thickness-macular-hole
#16
Se Rang Choi, Joon Won Kang, Ji Hoon Jeon, Joo Young Shin, Bum-Joo Cho, Baek-Lok Oh, Jang Won Heo
No abstract text is available yet for this article.
May 29, 2017: Retina
https://www.readbyqxmd.com/read/28557901/improving-the-age-related-macular-degeneration-construct-a-new-classification-system
#17
Richard F Spaide
Previous models of disease in age-related macular degeneration (AMD) were incomplete in that they did not encompass subretinal drusenoid deposits (pseudodrusen), subtypes of neovascularization, and polypoidal choroidal vasculopathy. In addition, Type 3 neovascularization starts in the retina and may not necessarily involve the choroid. As such, the term choroidal neovascularization is not appropriate for these eyes. The new aspects in the AMD construct are to include specific lipoprotein extracellular accumulations, namely drusen and subretinal drusenoid deposits, as early AMD...
May 26, 2017: Retina
https://www.readbyqxmd.com/read/28541961/double-staining-technique-with-brilliant-blue-g-and-its-effect-on-ganglion-cells-in-macular-pathology
#18
Hugo Sepulveda-Vazquez, Andree Henaine-Berra, Juan M Jimenez-Sierra, Virgilio Morales-Canton, Rodrigo Lechuga-Perezanta, Abril Santos-Palacios, Gerardo García-Aguirre
No abstract text is available yet for this article.
May 24, 2017: Retina
https://www.readbyqxmd.com/read/28541960/clinical-features-of-treated-and-untreated-type-1-idiopathic-macular-telangiectasia-without-the-occurrence-of-secondary-choroidal-neovascularization-followed-for-2-years-in-japanese-patients
#19
Rie Osaka, Chieko Shiragami, Aoi Ono, Mamoru Kobayashi, Yukari Takasago, Ayana Yamashita, Akitaka Tsujikawa
PURPOSE: To evaluate the clinical features of Type 1 idiopathic macular telangiectasia (IMT) followed up for 2 years. METHODS: Forty-nine patients with unilateral Type 1 IMT were examined. Thirty-one IMT eyes were treated with direct laser photocoagulation and/or intravitreal bevacizumab; the remaining 18 eyes, with good vision or slight macular edema, were untreated. Changes in best-corrected visual acuity and central retinal thickness between baseline and 24 months after the initial visit were examined...
May 24, 2017: Retina
https://www.readbyqxmd.com/read/28541959/longitudinal-correlation-of-ellipsoid-zone-loss-and-functional-loss-in-macular-telangiectasia-type-2
#20
Tjebo F C Heeren, Diána Kitka, Daniela Florea, Traci E Clemons, Emily Y Chew, Alan C Bird, Daniel Pauleikhoff, Peter Charbel Issa, Frank G Holz, Tunde Peto
PURPOSE: To compare ellipsoid zone (EZ) loss and functional loss in macular telangiectasia (MacTel) type 2 longitudinally. METHODS: Prospective natural history study. Ellipsoid zone loss was measured in en-face images created from spectral domain optical coherence tomography. Functional loss was assessed by best-corrected visual acuity and microperimetry, counting the number of test points with impaired function. RESULTS: A total of 56 eyes of 31 participants were followed for 4...
May 24, 2017: Retina
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