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https://www.readbyqxmd.com/read/29045321/fundus-wide-subretinal-and-pigment-epithelial-abnormalities-in-macular-telangiectasia-type-2
#1
Michael B Powner, Sasha M Woods, Meidong Zhu, Mark C Gillies, Paul S Bernstein, Gregory S Hageman, Grant M Comer, Catherine Egan, Marcus Fruttiger
PURPOSE: Macular telangiectasia Type 2 (MacTel) causes glial and photoreceptor cell death in a small, oval patch in the central retina. Beyond this oval area, no disease manifestations have been described so far. Here, we describe a novel pathological aspect of MacTel in the retinal pigment epithelium (RPE) that is not restricted to the clinically affected area but covers the entire retina. METHODS: We have studied postmortem eyes from four patients with MacTel by immunohistochemistry and electron microscopy...
October 17, 2017: Retina
https://www.readbyqxmd.com/read/29045320/autologous-lens-capsular-flap-transplantation-combined-with-autologous-blood-application-in-the-management-of-refractory-macular-hole
#2
Jie Peng, Chunli Chen, Haiying Jin, Hongtao Zhang, Peiquan Zhao
PURPOSE: To report results of lens capsular flap transplantation (LCFT) and autologous whole blood application in refractory macular hole (MH) treatment. METHODS: Seven phakic and three aphakic eyes with persistent MH after standard surgery with internal limiting membrane peeling were studied. Lens capsule flap was acquired from the same eye in eight cases (seven phakic and one aphakic). The fellow eye was used in two aphakic eyes without sufficient lens capsule...
October 17, 2017: Retina
https://www.readbyqxmd.com/read/29040227/testosterone-supplementation-and-retinal-vascular-disease
#3
Vaidehi S Dedania, David N Zacks, Wei Pan, Brian L VanderBeek
PURPOSE: To determine whether testosterone supplementation is associated with retinal artery occlusion (RAO) or retinal vein occlusion (RVO). METHODS: Retrospective matched cohort study using data from a large national U.S. insurance database. The testosterone cohort consisted of all male patients who filled a prescription for testosterone from 2000 to 2013. Five controls were matched on age (±3 years), sex, race, and similar time in plan (±3 months) for every exposed patient...
October 13, 2017: Retina
https://www.readbyqxmd.com/read/29028687/hyperreflective-deposition-in-the-background-of-advanced-stargardt-disease
#4
Lyam Ciccone, Winston Lee, Jana Zernant, Koji Tanaka, Kaspar Schuerch, Stephen H Tsang, Rando Allikmets
PURPOSE: To describe an unusual manifestation of hyperreflective deposits in the subretinal space in a group of patients with clinically and genetically confirmed Stargardt disease. METHODS: Retrospective review of color fundus, autofluorescence, infrared reflectance, red-free images, and spectral domain optical coherence tomography in 296 clinically diagnosed and genetically confirmed (2 expected disease-causing mutations in ABCA4) patients with Stargardt disease...
October 12, 2017: Retina
https://www.readbyqxmd.com/read/29023269/all-probe-vitrectomy-dissection-techniques-for-diabetic-tractional-retinal-detachments-lift-and-shave
#5
María H Berrocal
To describe a technique to relieve traction, remove fibrovascular tissue, and reattach the retina in cases of tractional retinal detachment secondary to complications of diabetes using only the vitrectomy probe. PURPOSE: To describe the all-probe lift and shave technique to remove fibrovascular tissue and repair diabetic retinal detachments. Anatomical and visual acuity outcomes with this technique are presented. METHODS: In this single surgeon, retrospective review of a consecutive series of eyes with tractional retinal detachment associated with diabetic retinopathy repaired with probe-only dissection techniques...
October 11, 2017: Retina
https://www.readbyqxmd.com/read/29019795/difference-in-treatment-outcomes-according-to-optical-coherence-tomography-based-stages-in-type-3-neovascularization-retinal-angiomatous-proliferation
#6
Jae Hui Kim, Young Suk Chang, Jong Woo Kim, Chul Gu Kim, Dong Won Lee, Soo Yeon Cho
PURPOSE: To compare 12-month treatment outcomes of Type 3 neovascularization among its different stages as classified using an optical coherence tomography-based method. METHODS: This retrospective observational study included 40 patients (40 eyes) who were newly diagnosed with Type 3 neovascularization. The patients were initially administered 3 monthly anti-vascular endothelial growth factor injections. Repeat treatment was performed when recurrence of fluid was noted...
October 10, 2017: Retina
https://www.readbyqxmd.com/read/29016455/reply
#7
Shunji Kusaka, Kuniko Tachibana, Daishi Tsujioka, Fumika Hotta, Hiroshi Eguchi, Yoshikazu Shimomura
No abstract text is available yet for this article.
October 9, 2017: Retina
https://www.readbyqxmd.com/read/29016454/intraocular-dexamethasone-implant-position-in-situ-and-ocular-hypertension
#8
Aditya Sudhalkar, Laurent Kodjikian, Jay Chhablani, Deepak Bhojwani, Abhay Vasavada
PURPOSE: To determine the association between the dexamethasone implant position in the vitreous cavity and ocular hypertension (OHT). METHODS: Retrospective review of patients with at least one intravitreal dexamethasone implant injection between 2012 and 2016. Patients who had a minimum follow-up for 6 months and documented evidence of the implant position were included in the study. Steroid responders, glaucoma patients, vitrectomized eyes, and eyes with liquefied vitreous were excluded...
October 9, 2017: Retina
https://www.readbyqxmd.com/read/29016453/in-vitro-flow-analysis-of-novel-double-cutting-open-port-ultrahigh-speed-vitrectomy-systems
#9
Claus Zehetner, Marion Moelgg, Emmanouil Bechrakis, Caroline Linhart, Nikolaos E Bechrakis
PURPOSE: To analyze the performance and flow characteristics of novel double-cutting, open-port, 23-, 25-, and 27-gauge ultrahigh-speed vitrectomy systems. METHODS: In vitro fluidic measurements were performed to assess the volumetric aspiration profiles of several vitrectomy systems in basic salt solution and egg white. RESULTS: Double-cutting open-port vitrectomy probes delivered stable aspiration flow rates that were less prone to flow variation affected by the cutting speed...
October 9, 2017: Retina
https://www.readbyqxmd.com/read/29016452/intraocular-lens-position-in-combined-phacoemulsification-and-vitreoretinal-surgery
#10
Serdar Ozates, Hasan Kiziltoprak, Mustafa Koc, Mehmet Murat Uzel, Mehmet Yasin Teke
PURPOSE: To assess the decentration and angle of tilt of the intraocular lens (IOL) according to the intravitreal tamponade types used in combined phacoemulsification and vitreoretinal surgery. METHODS: This prospective and randomized clinical study involved 73 eyes of 69 patients who underwent combined vitreoretinal surgery. Eyes with intravitreal tamponades formed the study group and eyes without intravitreal tamponades formed the control group. The study group was further divided into silicone oil and gas tamponade subgroups...
October 9, 2017: Retina
https://www.readbyqxmd.com/read/29016451/concurrent-idiopathic-macular-telangiectasia-type-2-and-central-serous-chorioretinopathy
#11
Alexandre Matet, Suzanne Yzer, Emily Y Chew, Alejandra Daruich, Francine Behar-Cohen, Richard F Spaide
PURPOSE: To describe cases presenting with features of idiopathic macular telangiectasia (MacTel) Type 2 and central serous chorioretinopathy (CSC). METHODS: Databases from four tertiary retina centers were searched for cases copresenting CSC and MacTel Type 2. RESULTS: Five cases were identified (4 men, 1 woman; mean age: 67.2 years). Four patients were referred for chronic or nonresolving CSC, and the diagnosis of MacTel Type 2 was made based on multimodal imaging findings...
October 9, 2017: Retina
https://www.readbyqxmd.com/read/29016450/a-new-design-intraocular-foreign-body-forceps
#12
Nur Acar
No abstract text is available yet for this article.
October 9, 2017: Retina
https://www.readbyqxmd.com/read/29016460/trefoil-factor-family-1-expression-correlates-with-clinical-outcome-in-patients-with-retinoblastoma
#13
Maike Busch, Klaus Metz, Manfred Beier, Eva Biewald, Nicole Dünker
PURPOSE: Correlation of trefoil factor family 1 (TFF1) expression in retinoblastoma tumors with different clinical parameters to evaluate a potential involvement of TFF1 in tumor development and progression. METHODS: A representative cohort of 59 enucleated eyes from individual patients with retinoblastoma was analyzed for its TFF1 expression profile by immuno staining and real-time PCR. Trefoil factor family 1 expression was correlated with demographics, laterality, tumor-node-metastasis stage, International Classification of Retinoblastoma, tumor differentiation level, and treatment...
October 6, 2017: Retina
https://www.readbyqxmd.com/read/29016459/choroidal-structural-changes-and-vascularity-index-in-stargardt-disease-on-swept-source-optical-coherence-tomography
#14
Dhanashree Ratra, Roy Tan, Durgasri Jaishankar, Neha Khandelwal, Arushi Gupta, Jay Chhablani, Rupesh Agrawal
PURPOSE: To evaluate structural changes in the choroid of patients with Stargardt disease using swept source optical coherence tomography scans. METHODS: A retrospective comparison cohort study was conducted on 39 patients with Stargardt disease, and on 25 age and gender matched-healthy controls. Subfoveal choroidal thickness (SFCT) was computed from the swept source optical coherence tomography machine, and the scans were binarized into luminal area and stromal areas, which were then used to derive choroidal vascularity index (CVI)...
October 6, 2017: Retina
https://www.readbyqxmd.com/read/29016458/quantitative-analysis-of-hyperautofluorescent-rings-to-characterize-the-natural-history-and-progression-in-rpgr-associated-retinopathy
#15
James J L Tee, Angelos Kalitzeos, Andrew R Webster, Tunde Peto, Michel Michaelides
PURPOSE: Quantitative analysis of hyperautofluorescent rings and progression in subjects with retinitis pigmentosa associated with retinitis pigmentosa GTPase regulator (RPGR) gene mutations. METHODS: Prospective observational study of 46 subjects. Ring area, horizontal and vertical diameter measurements taken from outer and inner ring borders. Intraobserver repeatability, baseline measurements, progression rates, interocular symmetry, and association with age and genotype were investigated...
October 6, 2017: Retina
https://www.readbyqxmd.com/read/29016457/optical-coherence-tomography-angiography-in-geographic-atrophy
#16
Riccardo Sacconi, Eleonora Corbelli, Adriano Carnevali, Lea Querques, Francesco Bandello, Giuseppe Querques
PURPOSE: To analyze choriocapillaris (CC) vessel density (VD) around geographic atrophy (GA) secondary to non-neovascular dry age-related macular degeneration using optical coherence tomography angiography. METHODS: We compared CC VD surrounding GA margin (500 μm radius) with control CC (outside GA margin) in a consecutive series of GA patients presenting between August 2016 and February 2017 at the Medical Retina and Imaging Unit of University Vita-Salute, IRCCS Ospedale San Raffaele in Milan...
October 6, 2017: Retina
https://www.readbyqxmd.com/read/29016456/new-ultra-wide-field-angiographic-grading-scheme-for-radiation-retinopathy-after-iodine-125-brachytherapy-for-uveal-melanoma
#17
Tara A McCannel, EunAh Kim, Mitchell Kamrava, James Lamb, Joseph Caprioli, Dong Yang, Colin A McCannel
PURPOSE: Radiation retinopathy remains incompletely characterized and may cause severe vision loss. Ultra-wide-field fluorescein angiography provides a pan-fundus view of vascular alterations caused by radiation treatment and may predict visual and ocular outcomes. We have developed a grading scheme to describe pan-fundus severity and to predict the progression of radiation retinopathy in patients treated for uveal melanoma with iodine-125 brachytherapy. METHODS: A retrospective review of patients treated with standard iodine-125 brachytherapy for uveal melanoma at the Ophthalmic Oncology Center at the University of California, Los Angeles, who had undergone both baseline and postbrachytherapy ultra-wide-field fluorescein angiography...
October 6, 2017: Retina
https://www.readbyqxmd.com/read/28991866/retinal-laser-and-photography-practice-eye-model-a-cost-effective-innovation-to-improve-training-through-simulation
#18
Pratyusha Ganne, Nagesha C Krishnappa, Prabu Baskaran, Syed M Sulaiman, Rengaraj Venkatesh
No abstract text is available yet for this article.
October 5, 2017: Retina
https://www.readbyqxmd.com/read/28991865/intraoperative-injection-of-intravitreal-dexamethasone-implant-using-a-vitrectomy-trocar-assisted-technique
#19
Sami H Uwaydat, Hans Wang, Ahmed B Sallam
No abstract text is available yet for this article.
October 5, 2017: Retina
https://www.readbyqxmd.com/read/28991864/bilateral-large-colloid-drusen-in-a-young-adult
#20
Chiara Veronese, Chiara Maiolo, Livia D Mora, Mariachiara Morara, Grayson W Armstrong, Antonio P Ciardella
No abstract text is available yet for this article.
October 5, 2017: Retina
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