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Tiezhu Lin, Kunny Dans, Amit Meshi, Ilkay Kilic Muftuoglu, Manuel J Amador-Patarroyo, Kevin C Chen, Lingyun Cheng, William R Freeman
PURPOSE: To characterize the natural history and response of age-related macular degeneration-associated peripapillary choroidal neovascularization to anti-vascular endothelial growth factor therapy. METHODS: This was a retrospective case series of patients with peripapillary choroidal neovascularization secondary to neovascular age-related macular degeneration. All patients underwent complete ophthalmologic examination and retinal imaging including fluorescein angiography and spectral domain optical coherence tomography at each visit...
July 17, 2018: Retina
Alexandre Matet, Alejandra Daruich, Samuel Hardy, Francine Behar-Cohen
PURPOSE: To investigate choriocapillaris flow signal void distribution on optical coherence tomography (OCT) angiography in central serous chorioretinopathy (CSCR) and its correlation to choroidal vessel morphology. METHODS: Fifty-three CSCR eyes (48 patients) and 34 healthy control eyes were included, retrospectively. Exclusion criteria were refractive error >2D, previous laser or photodynamic therapy, low-quality OCT angiography, or excessive shadowing artifacts...
July 17, 2018: Retina
Niharika Singh, Mukesh Jain, Durgasri Jaisankar, Tarun Sharma, Rajiv Raman
PURPOSE: To elucidate the clinical characteristics and surgical outcome of consecutive patients with bilateral simultaneous retinal detachment who reported to a tertiary eye care institution over a period of 10 years. METHODS: Retrospective interventional consecutive study of 168 eyes of 84 patients with bilateral simultaneous retinal detachment, observed by indirect ophthalmoscopy at the initial examination was performed. Demographic and clinical characteristics were collected before and after surgery...
July 17, 2018: Retina
Ling Yeung, Wei-Chi Wu, Lan-Hsin Chuang, Nan-Kai Wang, Chi-Chun Lai
PURPOSE: To evaluate the association between deep-superficial flow ratio (DSFR) and the treatment response of macular edema in branch retinal vein occlusion. METHODS: Thirty eyes from 30 patients with branch retinal vein occlusion who had received optical coherence tomography angiography examination were included. Seventeen normal fellow eyes acted as the control group. Patients were classified into the "good response group" and the "refractory group" by absence or presence of macular edema after 6 months of treatment...
July 17, 2018: Retina
J Jason McAnany, Jason C Park, Felix Y Chau, Yannek I Leiderman, Jennifer I Lim, Norman P Blair
PURPOSE: To evaluate retinal dysfunction in diabetic patients who have mild or no nonproliferative diabetic retinopathy (DR) using the high-frequency flicker electroretinogram. METHODS: Light-adapted flicker electroretinograms were recorded from 15 diabetic patients who have no clinically apparent retinopathy, 15 diabetic patients who have mild nonproliferative DR, and 15 nondiabetic, age-equivalent controls. Electroretinograms were elicited by full-field flicker at 2 temporal frequencies, 31...
July 16, 2018: Retina
Maxwell S Stem, Christianne A Wa, Bozho Todorich, Maria A Woodward, Mark K Walsh, Jeremy D Wolfe
PURPOSE: To determine whether haptic flanging during 27-gauge sutureless intrascleral fixation of intraocular lenses (IOLs) increases IOL stability and to report the short-term clinical outcomes of sutureless intrascleral surgery using 27-gauge trocar cannulas with haptic flanging. METHODS: Retrospective surgical case series using live and cadaveric human eyes. RESULTS: In the cadaveric experiment using five eyes, flanged haptics required more force to dislocate the IOL compared with unflanged haptics (14 ± 4 vs...
July 16, 2018: Retina
Jun Won Jang, Jong Min Kim, Se Woong Kang, Sang Jin Kim, Kunho Bae, Kyung Tae Kim
PURPOSE: To compare typical polypoidal choroidal vasculopathy (T-PCV) and polypoidal choroidal neovascularization (P-CNV), which can be defined as two subtypes of PCV, and to elucidate the significance of the classification. METHODS: Seventy-seven patients diagnosed with PCV and followed up for more than 12 months were reviewed. The PCV cases were divided into a T-PCV group (n = 36) and a P-CNV group (n = 41) according to the presence of features of pachychoroid or age-related macular degeneration...
July 16, 2018: Retina
Alia K Durrani, Edward F Cherney, Rohan J Shah, Shriji N Patel
No abstract text is available yet for this article.
July 13, 2018: Retina
Bobak Bahrami, Thomas Hong, Timothy E Schlub, Andrew A Chang
PURPOSE: To evaluate functional and anatomical outcomes after a switch from intravitreal bevacizumab to aflibercept in patients with persistent diabetic macular edema. METHODS: Prospective, single-arm, open-label clinical trial of patients with persistent diabetic macular edema, despite previous treatment with bevacizumab. Five loading doses of intravitreal aflibercept were administered every 4 weeks with subsequent injections administered every 8 weeks. Patients were reviewed every 4 weeks, and best-corrected visual acuity and central macular thickness were recorded...
July 13, 2018: Retina
Okan Toygar, Mert Mestanoglu, Christopher D Riemann
PURPOSE: To demonstrate a novel technique to measure the intraocular pressure in silicone oil (SO)-filled eyes with Boston Type 1 keratoprosthesis (KPro) during intraocular surgery. METHODS: In this retrospective case series, an ocular manometer that is predicated on a continuous fluid column between a pressure sensor and interior of the eye was designed and used to directly measure intraocular pressure during intraocular surgery in SO-filled eyes with KPro. RESULTS: Six eyes of six patients were included in the study...
July 13, 2018: Retina
Sarah Mrejen, Audrey Giocanti-Auregan, Sandrine Tabary, Salomon Y Cohen
PURPOSE: To evaluate the ability of optical coherence tomography angiography (OCTA) to detect abnormal vascular blood flow in Type 1 neovascularization (NV) with or without significant pigment epithelial detachment (PED). METHODS: Consecutive age-related macular degeneration patients with either treatment-naive or anti-vascular endothelial growth factor-treated Type 1 NV were divided into 2 groups based on the PED height on structural OCT: greater than 250 μm (Group 1) versus less than 250 μm (Group 2)...
July 13, 2018: Retina
Amit Meshi, Kevin C Chen, Qi Sheng You, Kunny Dans, Tiezhu Lin, Dirk-Uwe Bartsch, Lingyun Cheng, Manuel J Amador-Patarroyo, Ilkay Kilic Muftuoglu, Maria L Gomez, Eric Nudleman, William R Freeman
PURPOSE: To assess early retinal microvascular and functional changes in diabetic patients without clinical evidence of diabetic retinopathy with optical coherence tomography angiography and central visual analyzer. METHODS: This was an observational case-control study of diabetic patients without diabetic retinopathy and nondiabetic controls. Patients underwent optical coherence tomography angiography imaging and visual acuity testing using the central visual analyzer...
July 13, 2018: Retina
Elena Garcia-Martin, Alicia Gavin, Javier Garcia-Campayo, Elisa Vilades, Elvira Orduna, Vicente Polo, Jose M Larrosa, Luis E Pablo, Maria Satue
PURPOSE: To evaluate visual and retinal changes in patients with bipolar disorder. To analyze the correlation between structural changes and visual function parameters. METHODS: Thirty patients with bipolar disorder and 80 healthy controls underwent visual function evaluation with Early Treatment Diabetic Retinopathy Study charts at 100%, 2.50%, and 1.25% contrast, Pelli-Robson chart, and color vision Farnsworth and Lanthony tests. Analysis of the different retinal layers was performed using Spectralis optical coherence tomography with automated segmentation software...
July 13, 2018: Retina
Stanislao Rizzo, Fabrizio Giansanti, Lucia Finocchio, Tomaso Caporossi, Francesco Barca, Daniela Bacherini, Giulia Cocci, Martino Vannucchi, Ruggero Tartaro, Gianni Virgili
PURPOSE: To evaluate the functional and anatomical outcomes of 23-gauge or 25-gauge pars plana vitrectomy with internal limiting membrane peeling and air tamponade for the treatment of myopic foveoschisis. METHODS: Retrospective, noncomparative, interventional case series. The records of 29 patients (32 eyes), with myopic foveoschisis who were treated by 23-gauge or 25-gauge 3-port pars plana vitrectomy with internal limiting membrane peeling and air tamponade, were reviewed...
July 13, 2018: Retina
Takahiro Kogo, Yuki Muraoka, Sotaro Ooto, Kiyoshi Suzuma, Tomoaki Murakami, Yuto Iida, Yuko Iida-Miwa, Rima Ghashut, Manabu Miyata, Akitaka Tsujikawa
PURPOSE: To evaluate fixation status of eyes with branch retinal vein occlusion (BRVO) and to investigate its association with other clinical parameters. METHODS: This study included 57 consecutive eyes with BRVO after resolution of macular edema. Fixation status was determined by microperimetry. Defect length of the foveal ellipsoid zone band was measured by optical coherence tomography, and retinal perfusion status was assessed by optical coherence tomography angiography...
July 13, 2018: Retina
Andrew S H Tsai, Chee Wai Wong, Laurence Lim, Ian Yeo, Doric Wong, Edmund Wong, Chong Lye Ang, Sze Guan Ong, Shu Yen Lee, Gavin Tan
PURPOSE: To evaluate the clinical characteristics and surgical outcomes of pediatric retinal detachments (RDs) in an Asian population. METHODS: Retrospective review of 171 eyes of 152 pediatric patients with rhegmatogenous RD over a 20-year period. RESULTS: Myopia was the most common risk factor in our population. At 6 months, primary anatomical success was 60.7%, and overall anatomical success was 86.7%. A total of 46.8% had best-corrected visual acuity of 20/40 or better, and 81...
July 13, 2018: Retina
Brett T Foxman
No abstract text is available yet for this article.
July 11, 2018: Retina
Darshak S Patel, Imran J Khan, Mohammed G Zayed, Dave Partridge, Ian G Rennie, Hardeep S Mudhar, Richard Sheard
PURPOSE: To report on the diagnostic outcomes and safety of full diagnostic vitrectomy (FDV) with surgical posterior vitreous detachment induction for diagnosing vitritis of uncertain etiology. METHODS: Forty-nine patients underwent primary FDV using the cassette washings for histopathological analysis. In addition, an undiluted core vitreous sample was obtained for microbial analysis in suspected infective cases. Cases were retrospectively given a diagnosis of inflammatory, infective, or neoplastic based on the results at final follow-up and the outcome of primary FDV categorized as diagnostic or nondiagnostic...
July 10, 2018: Retina
Nicolas A Yannuzzi, Natalia F Callaway, Jayanth Sridhar, William E Smiddy
PURPOSE: To evaluate the visual and potential economic impact of primary internal limiting membrane (ILM) peeling in primary treatment of rhegmatogenous retinal detachment. METHODS: A PubMed search was performed to extract data regarding the rate of epiretinal membrane formation and the rate of secondary pars plana vitrectomy with membrane peel after repair of rhegmatogenous retinal detachment with or without ILM peeling. Data were aggregated and analyzed in a meta-analysis...
July 9, 2018: Retina
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