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Fernando J De Novelli, Mauro Goldbaum, Mario L R Monteiro, Fabio Bom Aggio, Walter Y Takahashi
PURPOSE: To study and compare visual acuity, foveal thickness, outer limiting layer, ellipsoid zone, and recurrence rate in patients undergoing removal of the epiretinal membrane with and without the removal of the internal limiting membrane (ILM). METHODS: Sixty-three patients who had the epiretinal membrane removed by a single surgeon were randomly assigned into 2 groups: Group 1 without additional removal of the ILM and Group 2 with removal of the ILM. Patients were followed up and evaluated at the first month, third month, and sixth month, postoperatively...
December 5, 2017: Retina
Gábor G Deák, Wolfgang M Schmidt, Reginald E Bittner, Georgios Mylonas, Philipp K Roberts, Stefan Zotter, Bernhard Baumann, Michael Pircher, Christoph K Hitzenberger, Ursula M Schmidt-Erfurth, Markus Ritter
PURPOSE: To examine the involvement of the retinal pigment epithelium (RPE) in the presence of vitelliform macular lesions (VML) in Best vitelliform macular dystrophy (BVMD), autosomal recessive bestrophinopathy, and adult-onset vitelliform macular degeneration using polarization-sensitive optical coherence tomography (PS-OCT). METHODS: A total of 35 eyes of 18 patients were imaged using a PS-OCT system and blue light fundus autofluorescence imaging. Pathogenic mutations in the BEST1 gene, 3 of which were new, were detected in all patients with BVMD and autosomal recessive bestrophinopathy...
December 5, 2017: Retina
Christian Böni, Mayss Al-Sheikh, Barbara Hasse, Roman Eberhard, Philipp Kohler, Pascal Hasler, Stefan Erb, Matthias Hoffmann, Daniel Barthelmes, Sandrine A Zweifel
PURPOSE: To explore morphologic characteristics of choroidal lesions in patients with disseminated Mycobacterium chimaera infection subsequent to open-heart surgery. METHODS: Nine patients (18 eyes) with systemic M. chimaera infection were reviewed. Activity of choroidal lesions were evaluated using biomicroscopy, fundus autofluorescence, enhanced depth imaging optical coherence tomography, fluorescein angiography/indocyanine green angiography, and optical coherence tomography angiography...
December 4, 2017: Retina
Stela Vujosevic, Andrea Muraca, Micol Alkabes, Edoardo Villani, Fabiano Cavarzeran, Luca Rossetti, Stefano De Cillaʼ
PURPOSE: To assess and compare early modifications in inner retinal layer thickness and optical coherence tomography angiography parameters in patients with diabetes mellitus (DM) Types 1 and 2 without clinical signs of diabetic retinopathy. METHODS: Ninety eyes of 90 subjects (24 Type 1 DM, 36 Type 2 DM, and 30 healthy controls) were prospectively evaluated with spectral domain OCT, swept-source OCT angiography, and color fundus photography (on the same day). Retinal nerve fiber layer, ganglion cell layer (GCL+), and nerve fiber layer + GCL+ (GCL++) thickness were automatically determined by the instrument in the 1, 3, and 6 central mm...
December 4, 2017: Retina
Carlos Mateo, Anniken Burés-Jelstrup
No abstract text is available yet for this article.
December 4, 2017: Retina
Eun Young Choi, Sung Chul Lee, Min Kim
No abstract text is available yet for this article.
December 4, 2017: Retina
SriniVas R Sadda, Pravin U Dugel, Victor H Gonzalez, Esmeralda Meunier, Petra Kozma
PURPOSE: To evaluate the effects of ocriplasmin and symptomatic vitreomacular adhesion resolution on visual fixation and macular sensitivity using microperimetry. METHODS: MP-1 parameters were analyzed from 3 OASIS sites after the use of standardized instruments and testing procedures over 24 months. RESULTS: A total of 27 patients (19 ocriplasmin, 8 sham) were evaluated. Mean distance of the preferred fixation locus to the anatomical center was farther in the sham group at baseline and farther in the sham versus ocriplasmin group throughout the study...
December 4, 2017: Retina
Eoi Jong Seo, June-Gone Kim
PURPOSE: To describe the retinal peripheral vascular morphology and to elucidate its relationship to microvascular abnormalities in normal fundus using ultra-widefield fluorescein angiography. METHODS: A total of 242 eyes from 167 consecutive patients were categorized into 3 groups: bilateral normal (n = 64), normal with contralateral eye affected with vascular disease (n = 82), and early diabetic eyes (n = 96). Peripheral vascular morphology was described and classified according to the shape...
December 1, 2017: Retina
Mathieu Lehmann, François Devin, Pierre-Raphael Rothschild, David Gaucher, Bruno Morin, Elise Philippakis, Pascale Massin, Aude Couturier, Ramin Tadayoni
PURPOSE: To determine the preoperative factors influencing visual recovery after vitrectomy for myopic foveoschisis. METHODS: Sixty-six eyes of 65 consecutive patients operated on for myopic foveoschisis were retrospectively included. All eyes underwent a preoperative ocular examination including best-corrected visual acuity (BCVA) and spectral domain optical coherence tomography with central foveal thickness measurement and foveal status classification: simple foveoschisis, foveal detachment, or macular hole...
December 1, 2017: Retina
Nasser Shoeibi, Mahdi Ghasemi, Sharon Fekrat, Dilraj S Grewal
No abstract text is available yet for this article.
November 28, 2017: Retina
Emily Y Chew, Martin Friedlander
No abstract text is available yet for this article.
November 28, 2017: Retina
Elon H C van Dijk, Rosa L Schellevis, Myrte B Breukink, Danial Mohabati, Greet Dijkman, Jan E E Keunen, Suzanne Yzer, Anneke I den Hollander, Carel B Hoyng, Eiko K de Jong, Camiel J F Boon
PURPOSE: To assess ophthalmologic characteristics in patients and unaffected individuals in families with multiple members affected by central serous chorioretinopathy (CSC), both at presentation and long-term follow-up. METHODS: In 103 subjects from 23 families with at least 2 affected patients with CSC per family, prospective extensive ophthalmologic examination was performed, including best-corrected visual acuity, indirect ophthalmoscopy, digital color fundus photography, optical coherence tomography, fundus autofluorescence, and fluorescein angiography imaging...
November 28, 2017: Retina
Lagan Paul, Gaganjeet S Gujral, Manisha Agarwal, Shalini Singh, Rahul Mayor, Ankita Shrivastav
No abstract text is available yet for this article.
November 28, 2017: Retina
Yukari Takasago, Chieko Shiragami, Mamoru Kobayashi, Rie Osaka, Aoi Ono, Ayana Yamashita, Akitaka Tsujikawa, Kazuyuki Hirooka
PURPOSE: To compare the areas of choriocapillaris (CC) nonperfusion and macular atrophy (MA) in treated exudative age-related macular degeneration. METHODS: This was a prospective, observational, cross-sectional study. Forty-four eyes exhibiting MA (42 patients with age-related macular degeneration), with a dry macula, underwent fundus autofluorescence and optical coherence tomography angiography. The area of MA detected by fundus autofluorescence and CC nonperfusion detected by optical coherence tomography angiography was measured using image analysis software...
November 28, 2017: Retina
Norie Nonobe, Hiroki Kaneko, Yasuki Ito, Kei Takayama, Keiko Kataoka, Taichi Tsunekawa, Toshiyuki Matsuura, Ayana Suzumura, Hideyuki Shimizu, Hiroko Terasaki
PURPOSE: To examine the characteristics of the foveal vascular structure of patients with retinopathy of prematurity (ROP) by optical coherence tomography angiography. METHODS: Ten patients with a history of laser photocoagulation or cryopexy treatment for Stage 3 (Zone ≥ II) ROP and 10 normal subjects (controls) were included. Foveal avascular zone, vessel density, vessel length, and vascular diameter index were measured by optical coherence tomography angiography using the 3 × 3-mm Early Treatment Diabetic Retinopathy Study (ETDRS) sectors...
November 28, 2017: Retina
Alessandro Invernizzi, Mariano Cozzi, Richard Symes, Marco Pellegrini, Giovanni Staurenghi
No abstract text is available yet for this article.
November 28, 2017: Retina
Andrea Cacciamani, Pamela Cosimi, Marta Di Nicola, Giuseppe Di Martino, Guido Ripandelli, Fabio Scarinci
PURPOSE: To examine the relationship between retinal layer thickness, retinal sensitivity, and visual function in patients with idiopathic epiretinal membrane using spectral domain optical coherence tomography automated segmentation algorithm. METHODS: Twenty-four eyes with epiretinal membrane and 12 control eyes were enrolled. Ophthalmic evaluations included best-corrected visual acuity, mean retinal sensitivity (MRS) of radial 10° and 4° areas tested with microperimetry, and measurements of 4 retinal layer thicknesses by means spectral domain optical coherence tomography...
November 28, 2017: Retina
Barbara Parolini, Dilraj S Grewal, Sajish J Pinackatt, Andrea Baldi, Attilio Di Salvatore, Gianluca Besozzi, Alessandro Finzi, Daniele Cardillo, Tamer H Mahmoud
PURPOSE: To evaluate the feasibility and initial functional and anatomical outcomes of transplanting a full-thickness free graft of choroid and retinal pigment epithelium (RPE), along with neurosensory retina in advanced fibrosis and atrophy associated with end-stage exudative age-related macular degeneration with and without a concurrent refractory macular hole. METHODS: During vitrectomy, an RPE-choroidal and neurosensory retinal free graft was harvested in nine eyes of nine patients...
November 23, 2017: Retina
Irini P Chatziralli, Panagiotis G Theodossiadis, David H W Steel
PURPOSE: To review the current rationale for internal limiting membrane (ILM) peeling in macular hole (MH) surgery and to discuss the evidence base behind why, when, and how surgeons peel the ILM. METHODS: Review of the current literature. RESULTS: Pars plana vitrectomy is an effective treatment for idiopathic MH, and peeling of the ILM has been shown to improve closure rates and to prevent postoperative reopening. However, some authors argue against ILM peeling because it results in a number of changes in retinal structure and function and may not be necessary in all cases...
November 23, 2017: Retina
Alexandra Miere, Pauline Butori, Salomon Y Cohen, Oudy Semoun, Vittorio Capuano, Camille Jung, Eric H Souied
PURPOSE: To describe the qualitative and quantitative changes in choroidal neovascularization (CNV) flow pattern after anti-vascular endothelial growth factor therapy, by optical coherence tomography angiography (OCTA). METHODS: Consecutive patients with neovascular age-related macular degeneration underwent multimodal imaging, including OCTA at initial examination and at last visit. High-flow networks in the choriocapillaris segmentation of OCTA were qualitatively and quantitatively analyzed at baseline and at follow-up, to characterize vascular flow changes after anti-vascular endothelial growth factor treatment and to correlate these changes with final exudation signs on spectral domain optical coherence tomography...
November 23, 2017: Retina
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