journal
https://read.qxmd.com/read/38394971/the-clinical-significance-of-hypoalbuminaemia
#21
JOURNAL ARTICLE
Simon P Allison, Dileep N Lobo
Albumin is a relatively small molecule with a radius of 7.5 nm and a molecular weight of 65 kDa. It is the most abundant protein in plasma, accounting for 60-75% of its oncotic pressure. Its concentration in plasma is merely one static measurement reflecting a dynamic and complex system of albumin physiology, and is the net result of several different processes, one or more of which may become deranged by disease or its treatment. It is also unsurprising that hypoalbuminaemia has proved to be an indicator of morbidity and mortality risk since the underlying conditions which cause it, including protein energy malnutrition, crystalloid overload, inflammation, and liver dysfunction are themselves risk factors...
February 22, 2024: Clinical Nutrition
https://read.qxmd.com/read/38471980/clinical-nutrition-in-primary-care-espen-position-paper
#22
EDITORIAL
Željko Krznarić, Darija Vranešić Bender, Milena Blaž Kovač, Cristina Cuerda, Annemieke van Ginkel-Res, Michael Hiesmayr, Anibal Marinho, Juan Mendive, Isabel Monteiro, Matthias Pirlich, Sanja Musić Milanović, Nada Rotovnik Kozjek, Stephane Schneider, Michael Chourdakis, Rocco Barazzoni
Primary care healthcare professionals (PCHPs) are pivotal in managing chronic diseases and present a unique opportunity for nutrition-related disease prevention. However, the active involvement of PCHPs in nutritional care is limited, influenced by factors like insufficient education, lack of resources, and time constraints. In this position paper The European Society for Clinical Nutrition and Metabolism (ESPEN) promotes the active engagement of PCHPs in nutritional care. We emphasize the importance of early detection of malnutrition by screening and diagnosis, particularly in all individuals presenting with risk factors such as older age, chronic disease, post-acute disease conditions and after hospitalization for any cause...
February 21, 2024: Clinical Nutrition
https://read.qxmd.com/read/38382419/circulating-microrna-19-and-cardiovascular-risk-reduction-in-response-to-weight-loss-diets
#23
JOURNAL ARTICLE
Qiaochu Xue, Yoriko Heianza, Xiang Li, Xuan Wang, Hao Ma, Jennifer Rood, Kirsten S Dorans, Katherine T Mills, Xiaowen Liu, George A Bray, Frank M Sacks, Lu Qi
OBJECTIVE: MicroRNA-19 (miR-19) plays a critical role in cardiac development and cardiovascular disease (CVD). We examined whether change in circulating miR-19 was associated with change in CVD risk during weight loss. METHODS: This study included 509 participants with overweight or obesity from the 24-month weight-loss diet intervention study (the POUNDS Lost trial) and with available data on circulating miR-19a-3p and miR-19b-3p at baseline and 6 months. The primary outcome for this analysis was the change in atherosclerotic CVD (ASCVD) risk at 6 and 24 months, which estimates the 10-year probability of hard ASCVD events...
February 15, 2024: Clinical Nutrition
https://read.qxmd.com/read/38368149/reply-letter-to-the-editor-red-blood-cell-distribution-width-is-an-inflammatory-but-not-a-nutritional-biomarker
#24
LETTER
Philipp Schuetz, Eliane Haenggi, Carla Wunderle
No abstract text is available yet for this article.
February 15, 2024: Clinical Nutrition
https://read.qxmd.com/read/38368148/red-blood-cell-distribution-width-is-an-inflammatory-but-not-a-nutritional-biomarker
#25
LETTER
Jialu Wang, Renying Xu
No abstract text is available yet for this article.
February 15, 2024: Clinical Nutrition
https://read.qxmd.com/read/38367595/the-effect-of-chrono-nutritional-manipulation-of-carbohydrate-intake-on-sleep-macrostructure-a-randomized-controlled-trial
#26
JOURNAL ARTICLE
Angelos Vlahoyiannis, Eleni Andreou, Panagiotis Bargiotas, George Aphamis, Giorgos K Sakkas, Christoforos D Giannaki
BACKGROUND & AIMS: Over the years, there is a rapid increase in the prevalence of inadequate sleep and its detrimental consequences. Yet, the impact of prolonged nutritional interventions on sleep optimization remains unexplored. To examine the effect of carbohydrate manipulation combined with exercise training on sleep macro-structure. METHODS: Forty-two healthy, trained male volunteers were recruited for this study. The 4-week intervention consisted of three groups: i) Sleep Low-No Carbohydrates (SL-NCHO): participants consumed all their carbohydrate intake at regular intervals prior to evening training, ii) Sleep High-Low Glycemic Index (SH-LGI) and iii) Sleep High-High Glycemic Index (SH-HGI): Carbohydrate intake was spread throughout the day, both prior (60% of total CHO intake) and after evening training (40% of total CHO intake)...
February 15, 2024: Clinical Nutrition
https://read.qxmd.com/read/38365505/red-cell-distribution-width-as-a-nutritional-risk-biomarker-practical-or-historical
#27
LETTER
Gözde Şengül Ayçiçek
No abstract text is available yet for this article.
February 15, 2024: Clinical Nutrition
https://read.qxmd.com/read/38367596/direct-oral-and-fiber-derived-butyrate-supplementation-as-an-anti-obesity-treatment-via-different-targets
#28
JOURNAL ARTICLE
Zuzanna Majka, Barbara Zapala, Agnieszka Krawczyk, Krzysztof Czamara, Joanna Mazurkiewicz, Ewa Stanek, Izabela Czyzynska-Cichon, Mariusz Kepczynski, Dominika Salamon, Tomasz Gosiewski, Agnieszka Kaczor
BACKGROUND & AIMS: Butyric (one of the short-chain fatty acids), a major byproduct of the fermentation of non-digestible carbohydrates (e.g. fiber), is supposed to have anti-obesity and anti-inflammatory properties. However, butyrate's potential and mechanism in preventing obesity and the efficient form of administration remain to be clarified. METHODS: Hence, we studied the effect of oral supplementation with 5% (w/w) sodium butyrate and 4% (w/w) β-glucan (fiber) on young male mice (C57BL/6J) with high-fat diet-induced obesity (HFD: 60 kcal% of fat + 1% of cholesterol)...
February 13, 2024: Clinical Nutrition
https://read.qxmd.com/read/38513551/zinc-unbound-concentration-as-an-anchor-to-drive-individualize-repletion
#29
JOURNAL ARTICLE
D Metsu, C Cinq-Frais, C Camare, S Caspar-Bauguil, A Galinier
BACKGROUND AND AIMS: Zinc (Zn) quantification is of particular interest in many clinical condition (e.g. inflammatory disease, critical care). Currently, Zn status is assessed by measuring plasma/serum concentration. This concentration corresponds to the sum of unbound Zn (Zn-Cu ) and Zn highly bound to albumin (Zn-Cb ). METHODS: Using a pharmacokinetic approach to the interpretation of total Zn concentration (Zn-Ct ), taking into account Zn-Cu and the influence of hypoalbuminemia on Zn-Cb , it is possible to improve the individualization of Zn repletion...
February 12, 2024: Clinical Nutrition
https://read.qxmd.com/read/38387279/non-invasive-tools-for-liver-steatosis-and-steatohepatitis-predict-incidence-of-diabetes-cardiovascular-disease-and-mortality-20-years-later-the-attica-cohort-study-2002-2022
#30
JOURNAL ARTICLE
Matina Kouvari, Christina Chrysohoou, Evangelia Damigou, Fotios Barkas, Evrydiki Kravvariti, Evangelos Liberopoulos, Costas Tsioufis, Petros P Sfikakis, Christos Pitsavos, Demosthenes Panagiotakos, Christos S Mantzoros
BACKGROUND & AIMS: Non-alcoholic fatty liver disease (NAFLD) or, as recently renamed, metabolic dysfunction-associated steatotic liver disease (MASLD), has common metabolic pathways with diabetes and cardiovascular disease (CVD). Non-invasive tools (NITs) for liver steatosis and steatohepatitis (MASH) were studied as potential predictors of diabetes, cardiovascular disease (CVD) and mortality over a 20-year period. METHODS: In 2001-02, 3042 individuals from the Attica region of Greece were recruited randomly, and were stratified by subgroups of sex, age and region to reflect the general urban population in Athens, Greece...
February 10, 2024: Clinical Nutrition
https://read.qxmd.com/read/38350288/the-severity-of-early-fluid-overload-assessed-by-bioelectrical-vector-impedance-as-an-independent-risk-factor-for-longer-patient-care-after-cardiac-surgery
#31
JOURNAL ARTICLE
Gianfranco Sanson, Lisa Doriguzzi, Pierpaolo Garbari, Maria Josè Ruggiero, Ilaria Valentinuzzo, Tanja Mettulio, Elisa Stolfa, Manuela Fisicaro, Sara Vecchiet, Enzo Mazzaro, Michela Zanetti, Adam Fabiani
BACKGROUND AND AIMS: Fluid overload is a common postoperative complication in patients undergoing cardiac surgery. Although this condition is notably associated with relevant adverse outcomes, assessment of hydration status in clinical practice is challenging. Bioelectrical impedance vector analysis (BIVA) has emerged as a potentially effective method to monitor hydration changes, but the available evidence in critically ill patients undergoing cardiac surgery is limited and sometimes conflicting...
February 8, 2024: Clinical Nutrition
https://read.qxmd.com/read/38377634/predicting-malnutrition-in-gastric-cancer-patients-using-computed-tomography-ct-deep-learning-features-and-clinical-data
#32
JOURNAL ARTICLE
Weijia Huang, Congjun Wang, Ye Wang, Zhu Yu, Shengyu Wang, Jian Yang, Shunzu Lu, Chunyi Zhou, Erlv Wu, Junqiang Chen
OBJECTIVE: The aim of this study is using clinical factors and non-enhanced computed tomography (CT) deep features of the psoas muscles at third lumbar vertebral (L3) level to construct a model to predict malnutrition in gastric cancer before surgery, and to provide a new nutritional status assessment and survival assessment tool for gastric cancer patients. METHODS: A retrospective analysis of 312 patients of gastric cancer were divided into malnutrition group and normal group based on Nutrition Risk Screening 2002(NRS-2002)...
February 6, 2024: Clinical Nutrition
https://read.qxmd.com/read/38350287/associations-between-sarcopenic-obesity-and-risk-of-cardiovascular-disease-a-population-based-cohort-study-among-middle-aged-and-older-adults-using-the-charls
#33
JOURNAL ARTICLE
Minglan Jiang, Xiao Ren, Longyang Han, Xiaowei Zheng
BACKGROUND: Previous studies have demonstrated that sarcopenia was associated with a high risk of cardiovascular disease (CVD). Nevertheless, little is known about the associations between sarcopenic obesity/possibly sarcopenic obesity and the risk of CVD among senior and middle-aged adults. METHODS: Utilizing the nationally representative data from the China Health and Retirement Longitudinal Study (CHARLS), a sum of 7703 individuals aged at least 45 years were divided into four groups...
February 6, 2024: Clinical Nutrition
https://read.qxmd.com/read/38350289/integrated-assessment-of-computed-tomography-density-in-pectoralis-and-erector-spinae-muscles-as-a-prognostic-biomarker-for-coronavirus-disease-2019
#34
JOURNAL ARTICLE
Kensuke Nakagawara, Yusuke Shiraishi, Shotaro Chubachi, Naoya Tanabe, Tomoki Maetani, Takanori Asakura, Ho Namkoong, Hiromu Tanaka, Takashi Shimada, Shuhei Azekawa, Shiro Otake, Takahiro Fukushima, Mayuko Watase, Hideki Terai, Mamoru Sasaki, Soichiro Ueda, Yukari Kato, Norihiro Harada, Shoji Suzuki, Shuichi Yoshida, Hiroki Tateno, Yoshitake Yamada, Masahiro Jinzaki, Toyohiro Hirai, Yukinori Okada, Ryuji Koike, Makoto Ishii, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga
UNLABELLED: BACKGROUND & AIMS: Muscle quantification using chest computed tomography (CT) is a useful prognostic biomarker for coronavirus disease 2019 (COVID-19). However, no studies have evaluated the clinical course through comprehensive assessment of the pectoralis and erector spinae muscles. Therefore, we compared the impact of the areas and densities of these muscles on COVID-19 infection outcome. METHODS: This multicenter retrospective cohort study was conducted by the COVID-19 Task Force...
February 5, 2024: Clinical Nutrition
https://read.qxmd.com/read/38340410/home-enteral-nutrition-does-not-decrease-oral-feeding-in-children-during-the-first-year-of-nutritional-support
#35
JOURNAL ARTICLE
L Zambelli, M Aumar, D Ley, M Antoine, S Coopman, J Morcel, E Bequet, D Guimber, E Cailliau, N Peretti, F Gottrand
BACKGROUND: Enteral nutrition is necessary when nutritional status is poor and oral intake is insufficient or impossible. Although it has been suspected to reduce spontaneous oral feeding, no study has formally assessed the influence of enteral nutrition on pediatric oral intake. The present study aimed to evaluate variation in oral feeding intake after enteral nutrition initiation, and to identify factors influencing oral feeding. METHODS: This retrospective cohort study included 149 pediatric patients from two French tertiary care hospitals, who received home enteral nutrition from 2009 to 2022...
February 5, 2024: Clinical Nutrition
https://read.qxmd.com/read/38335802/improvement-of-muscle-quality-assessed-using-the-phase-angle-is-influenced-by-recovery-of-knee-extension-strength-in-patients-with-hip-fractures
#36
JOURNAL ARTICLE
Takuya Umehara, Akinori Kaneguchi, Keita Watanabe, Nobuhisa Katayama, Hidefumi Teramoto, Daisuke Kuwahara, Ryo Kaneyashiki, Toshiyuki Mizuno, Nobuhiro Kito, Masayuki Kakehashi
BACKGROUND AND AIMS: Studies reported that knee extension strength on the operated side in patients with hip fractures was not recovered to the level on the non-operated side 6 months after surgery or later. In a cross-sectional study, we revealed that a reduction in isometric knee extension muscle strength on the operated side in patients with hip fractures approximately 6 months after surgery was associated with not only a reduction in skeletal muscle mass but also a reduction in muscle quality, characterized by a reduction in the phase angle (PhA)...
February 5, 2024: Clinical Nutrition
https://read.qxmd.com/read/38330703/weight-gain-during-nutritional-rehabilitation-post-childhood-malnutrition-may-influence-the-associations-between-adulthood-desaturases-activity-and-anthro-cardiometabolic-risk-factors
#37
JOURNAL ARTICLE
Laurentya Olga, Kimberley McKenzie, Marko Kerac, Michael Boyne, Asha Badaloo, Robert H J Bandsma, Albert Koulman, Debbie S Thompson
BACKGROUNDS & AIMS: Childhood malnutrition is a major global health problem with long-term sequelae, including non-communicable diseases (NCDs). Mechanisms are unknown but may involve metabolic programming, resulting from "short-term" solutions to optimise survival by compromising non-priority organs. As key players in lipid metabolism, desaturases have been shown to be predictive of NCDs. We hypothesised that the association between specific desaturase activities and NCD risk determinants (including body composition, serum glucose, insulin levels, and blood pressure) are influenced by childhood post-malnutrition weight gain...
February 2, 2024: Clinical Nutrition
https://read.qxmd.com/read/38335801/novel-equations-incorporating-the-sarcopenia-index-based-on-serum-creatinine-and-cystatin-c-to-predict-appendicular-skeletal-muscle-mass-in-patients-with-nondialysis-ckd
#38
JOURNAL ARTICLE
Bang-Gee Hsu, Chih-Hsien Wang, Yu-Hsien Lai, Chiu-Huang Kuo, Yu-Li Lin
BACKGROUND & AIMS: Skeletal muscle mass measurements are important for customizing nutritional strategies for patients with chronic kidney disease (CKD). The serum creatinine-to-cystatin C ratio (Cr/CysC) is a potential indicator of sarcopenia. We developed simple equations to predict the appendicular skeletal muscle mass (ASM) of patients with CKD using readily available parameters and Cr/CysC. METHODS: Overall, 573 patients with nondialysis CKD stages 3-5 were included for developing and validating the equations...
February 1, 2024: Clinical Nutrition
https://read.qxmd.com/read/38320463/association-between-protein-intake-and-risk-of-gestational-diabetes-mellitus-a-systematic-review-and-dose-response-meta-analysis-of-cohort-studies
#39
JOURNAL ARTICLE
Razieh Tabaeifard, Maedeh Moradi, Pishva Arzhang, Leila Azadbakht
BACKGROUND: Gestational diabetes mellitus (GDM) is a common condition in pregnancy, the prevalence of which has increased. Identifying modifiable risk factors for GDM, such as dietary factors, could prevent or delay the onset of the condition. Our goal was to perform a comprehensive meta-analysis of cohort studies, to summarize the current evidence on the relationship between total, animal, and plant protein intake during pregnancy, as well as pre-pregnancy protein intake, and the risk of GDM...
January 30, 2024: Clinical Nutrition
https://read.qxmd.com/read/38320462/the-effects-of-protein-intake-higher-than-the-recommended-value-on-body-composition-changes-after-bariatric-surgery-a-meta-analysis-of-randomized-controlled-trials
#40
JOURNAL ARTICLE
Mahdieh Golzarand, Karamollah Toolabi, Parvin Mirmiran
BACKGROUND & AIMS: There is a lack of a meta-analysis to comprehensively assess the effectiveness of higher protein intake in addition to the recommended value on body composition post-bariatric surgery. We aimed to perform a meta-analysis of randomized controlled trials to determine the effects of protein intake higher than the recommended value on body composition changes after bariatric surgery. METHODS: Electronic databases, including Scopus, PubMed/Medline, and Web of Sciences, were searched until July 2023...
January 30, 2024: Clinical Nutrition
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