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Journal of Hypertension

Shahabeddin Rezaei, Zohreh Mahmoudi, Ali Sheidaei, Zahra Aryan, Negar Mahmoudi, Kimiya Gohari, Moein Yoosefi, Mohammad J Hajipour, Arezou Dilmaghani-Marand, Mojdeh Soleimanzadehkhayat, Ali Gholami, Siamak Mirab Samiee, Ghobad Moradi, Bagher Larijani, Farshad Farzadfar
OBJECTIVE: In Iran, there has been no national report on salt intake based on laboratory measurements so far. Therefore, this study was conducted to measure salt intake among Iranian population at the national level. METHODS: In stepwise approach to conduct a surveillance survey 2016, 18 624 Iranian adults (25 years old and above), as a representative sample of Iranian adult population at national and subnational levels, underwent urine sodium measurement and were included in this study...
July 12, 2018: Journal of Hypertension
Paolo Palatini, Francesca Saladini, Lucio Mos, Claudio Fania, Adriano Mazzer, Edoardo Casiglia
OBJECTIVE: The clinical significance of isolated systolic hypertension (ISH) in youth is controversial. One main confounding factor is the strong white-coat effect often observed in ISH patients. The aim of this study was to investigate the risk of hypertension needing pharmacological treatment in ISH identified with ambulatory 24-h blood pressure (24-h BP). METHODS: We examined 1206, 18-45-year-old participants from the Hypertension and Ambulatory Recording VEnetia STudy...
July 12, 2018: Journal of Hypertension
Milan Wolf, Brad Hubbard, Atsushi Sakaoka, Serge Rouselle, Armando Tellez, Xiongjing Jiang, Kazuomi Kario, Mathias Hohl, Michael Böhm, Felix Mahfoud
INTRODUCTION: Several renal denervation (RDN) systems are currently under investigation for treatment of hypertension by ablation of renal sympathetic nerves. The procedural efficacy of devices, however, is variable and incomplete understood. This study aimed at investigating procedural and anatomical predictors of RDN efficacy by comparing two radiofrequency catheter systems in a porcine model. METHODS: Domestic swine were assigned into two treatment groups (n = 10) and one sham group (n = 3)...
July 11, 2018: Journal of Hypertension
Xiaolei Yang, Tesfaldet H Hidru, Binhao Wang, Xu Han, Huihua Li, Shouling Wu, Yunlong Xia
BACKGROUND: Resting heart rate (RHR) and SBP are important risk markers for all-cause mortality. However, the link between increased RHR and SBP for all causes of death remained unclear. We investigated the link between an increased visit-to-visit variation of RHR and SBP for risk of all-cause mortality in the general population. METHODS: We examined long-term visit-to-visit variation of RHR and blood pressure among 46 751 residents of Tangshan city, China (mean age: 52...
July 11, 2018: Journal of Hypertension
Yanping Xu, Peilin Xiao, Jinqi Fan, Weijie Chen, Huaan Du, Zhiyu Ling, Zengzhang Liu, Li Su, Kamsang Woo, Yuehui Yin
BACKGROUND: Previous studies showed that radiofrequency energy delivery of the renal artery could induce an immediate and substantial blood pressure (BP)-elevation response, which might be indicative of the increase in central sympathetic nervous activity. OBJECTIVE: The current study was to investigate whether the presence of BP-elevation response to radiofrequency energy delivery can serve as a surrogate to predict BP reduction following renal artery sympathetic denervation (RDN)...
July 11, 2018: Journal of Hypertension
Martin Müller, Mareike Österreich, Alexander von Hessling, Roy S Smith
OBJECTIVE: Whether cerebrovascular regulation is different in patients with controlled high blood pressure (HBP) with and without small vessel disease (SVD). METHODS: Sixty-seven healthy controls (mean age ± SD, 45 ± 16 years; 30 women, 37 men) and 40 patients (mean age, 64 ± 13 years; 14 women, 26 men) with HBP and different stages of SVD, underwent simultaneous recordings of the spontaneous fluctuations of BP, blood flow velocity (CBFV) in both middle cerebral arteries (MCA), and of end-tidal CO2 (ETCO2)...
July 10, 2018: Journal of Hypertension
Giuseppe Mancia
No abstract text is available yet for this article.
July 10, 2018: Journal of Hypertension
Alexandre Vallée, Alexandra Yannoutsos, Mohamed Temmar, Céline Dreyfuss Tubiana, Irina Spinu, Yi Zhang, Athanase Protogerou, Guillaume Henry-Bonniot, Philippe Sosner, Michel E Safar, Jacques Blacher
OBJECTIVE: Aortic stiffness may provide information to classical risk factors information regarding cardiovascular risk. Aortic pulse wave velocity (PWV) can be measured by applanation tonometry but also theoretical PWV was calculated according to age, blood pressure, heart rate and sex. We aim to highlight biological and hemodynamic determinants of the aortic PWV index, that is the individually calculated [(measured PWV - theoretical PWV)/theoretical PWV] difference, in hypertensive diabetic patients...
July 10, 2018: Journal of Hypertension
Silvio Borrelli, Carlo Garofalo, Francesca Mallamaci, Giovanni Tripepi, Giovanna Stanzione, Michele Provenzano, Giuseppe Conte, Luca De Nicola, Carmine Zoccali, Roberto Minutolo
OBJECTIVE: In chronic kidney disease (CKD), few cross-sectional studies evidenced an association between short-term BP variability (BPV) derived from ambulatory blood pressure (ABP) monitoring and renal damage. However, no study has evaluated the association of short-term BPV with the risk of CKD progression. METHODS: We performed a cohort study to assess the correlates and the predictive value for incident renal outcomes of short-term BPV in hypertensive patients with CKD stage G1-5...
July 10, 2018: Journal of Hypertension
Dinah S Khatir, Michael Pedersen, Per Ivarsen, Kent L Christensen, Bente Jespersen, Niels H Buus
AIM: Progression of chronic kidney disease (CKD) may be accelerated by tissue hypoxia due to impaired blood supply. This could be induced by small artery narrowing resulting in abnormally high intrarenal vascular resistance (RVR). We investigated whether a reduction in RVR achieved by adding vasodilating medical therapy (AVT) is superior to adding nonvasodilating medical therapy (AnonVT) regarding tissue oxygenation and preservation of kidney function. METHODS: Eighty-three grade 3 and 4 CKD patients [estimated glomerular filtration rate (GFR) 34...
July 10, 2018: Journal of Hypertension
Maria Hoeltzenbein, Anne-Katrin Fietz, Angela Kayser, Sandra Zinke, Reinhard Meister, Corinna Weber-Schoendorfer, Christof Schaefer
OBJECTIVES: Beta-blockers are frequently used during pregnancy, with labetalol and metoprolol being considered as drugs of choice. As there are no prospective pregnancy studies for bisoprolol yet, our aim was to analyze pregnancy outcomes after bisoprolol exposure. METHODS: Pregnancies exposed to bisoprolol during the first trimester were retrieved from the German Embryotox pharmacovigilance database. Pregnancy outcomes of prospectively ascertained pregnancies were compared with women neither exposed to beta-blockers nor other antihypertensives...
July 5, 2018: Journal of Hypertension
Weiwei He, Sheli Li, Bin Wang, Kaida Mu, Xiaoqing Shao, Qiuming Yao, Ling Li, Qian Li, Jin-An Zhang
BACKGROUND: The adverse impact of thyroid dysfunction on cardiovascular system is well established, but the relationship between the level of thyroid stimulating hormone (TSH) and the risk of hypertension in euthyroid individuals is still inconclusive. METHODS: We carried out a population-based, cross-sectional study to evaluate the relationship between TSH and hypertension risk in euthyroid individuals, and logistic regression analysis was utilized. In addition, a dose-response meta-analysis of relevant cohort or cross-sectional studies was carried out to further assess the impact of TSH on hypertension risk among euthyroid individuals...
July 5, 2018: Journal of Hypertension
Cesare Cuspidi, Rita Facchetti, Michele Bombelli, Carla Sala, Marijana Tadic, Guido Grassi, Giuseppe Mancia
AIM: In the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study, clinical and metabolic variables as well as office, home and ambulatory blood pressure (BP) values were simultaneously measured at baseline and after a 10-year follow-up. The study design allowed us to assess the value of selective and combined elevation of different BP phenotypes in predicting new-onset metabolic syndrome (MetS). METHODS: The present analysis included 1182 participants without MetS at baseline, as defined by the APT III criteria...
June 29, 2018: Journal of Hypertension
Lidia Gackowska, Jacek Michałkiewicz, Anna Niemirska, Anna Helmin-Basa, Maciej Kłosowski, Izabela Kubiszewska, Łukasz Obrycki, Mieczysław Szalecki, Aldona Wierzbicka, Zbigniew Kułaga, Malgorzata Wiese, Mieczysław Litwin
BACKGROUND: Primary hypertension is associated with still poorly known T-cell dependent immunity defects that participate in the disease development. However, the relationship between peripheral T-cell subset distribution and disease severity in humans is not known. The aim of the study was to find out if target organ damage in adolescents with primary hypertension is associated with thymus-dependent lymphocytes renewal reflected by changes in the T-cell subset phenotype characteristics...
June 29, 2018: Journal of Hypertension
Marijana Tadic, Cesare Cuspidi, Vera Celic, Branislava Ivanovic, Biljana Pencic, Guido Grassi
OBJECTIVE: The aim of this study was to evaluate the influence of sex on left ventricular mechanics in hypertensive individuals. METHODS: This cross-sectional study included 171 untreated hypertensive patients and 112 normotensive controls who underwent a 24-h ambulatory blood pressure monitoring and comprehensive echocardiographic examination including strain assessment. RESULTS: Hypertensive women and men had significantly lower left ventricular global longitudinal and circumferential strains than their normotensive counterparts...
June 29, 2018: Journal of Hypertension
Edmilson R Marques, Tiago Gemignani, Renata C Azevedo, Celina M Higa, Otavio R Coelho-Filho, José R Matos-Souza, Andrei C Sposito, Wilson Nadruz
OBJECTIVE: Smoking increases the risk of peripheral artery disease, but the mechanisms are not well established. This study evaluated the association of local circumferential wall tension (CWT), markers of vascular remodeling and stiffness, and traditional risk factors with popliteal and carotid plaques among smokers and nonsmokers. METHODS: Two hundred fifty-two individuals (126 smokers and 126 nonsmokers) underwent clinical, laboratory, and popliteal and carotid ultrasound analysis...
June 27, 2018: Journal of Hypertension
Gerard Ngueta, Ruth Ndjaboue
OBJECTIVES: We examined whether the early initiation of sexual activity is associated with hypertension in US adults, and whether the timing of first menstruation is meaningful in regard of this association. We also assessed the effect modification by ethnicity. METHODS: Using data from 2001 to 2016 National Health and Nutrition Examination Survey, we included 39 788 women. The association of age at the first sexual intercourse (FSI) and hypertension (SBP ≥ 130 mmHg or DBP ≥ 80 mmHg) was examined using multivariate logistic regression...
June 27, 2018: Journal of Hypertension
Liling Xie, Binyan Wang, Chongfei Jiang, Xianglin Zhang, Yun Song, Youbao Li, Jiancheng Wang, Yaren Yu, Min Liang, Guobao Wang, Yan Zhang, Jianping Li, Yong Huo, Xiping Xu, Jing Nie, Xianhui Qin
OBJECTIVE: We aimed to investigate the relationship of BMI and waist circumference with the development of chronic kidney disease (CKD). METHODS: A total of 12 672 hypertensive patients with estimated glomerular filtration rate (eGFR) at least 60 ml/min per 1.73 m from the renal sub-study of the China Stroke Primary Prevention Trial (CSPPT) were included. The primary outcome was the development of CKD, defined as a decrease in eGFR of at least 30% and to a level of less than 60 ml/min per 1...
June 27, 2018: Journal of Hypertension
Bo Xiong, Jianbo Li, Yuanqing Yao, Jun Qian, Shunkang Rong, Peng Zhang, Rong Jiang, Gang Yang, Que Zhu, Yonghong Jiang, Qi Zhou, Dichuan Liu, Changming Deng, Jing Huang
BACKGROUND: The role of renal sympathetic nerve (RSN) in hypertension should be better understood. We aimed to three-dimensionally reconstruct the renal nerves, and explore its anatomical and histochemical characteristics in hypertensive canine model and patients. METHODS: Renal arteries with surrounding tissue were collected from canines and cadavers with or without hypertension. Serial renal artery hematoxylin-eosin sections were used for three-dimensional reconstruction, and morphological parameters were collected and analyzed...
June 27, 2018: Journal of Hypertension
Cong Sun, Anne-Louise Ponsonby, John B Carlin, Minh Bui, Costan G Magnussen, Trudy L Burns, Terho Lehtimaki, Nicole H Wardrop, Markus Juonala, Jorma S A Viikari, Alison J Venn, Olli T Raitakari, Terence Dwyer
BACKGROUND: Genetic variants may modify the associations of adiposity measures with blood pressure (BP) and hypertension. The insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme (ACE) gene is an attractive candidate. AIMS: To examine interaction effects between I/D polymorphism and adiposity measures (BMI, waist circumference, waist-to-hip ratio, and skinfold thickness) during childhood and adulthood in relation to adult BP and hypertension...
June 22, 2018: Journal of Hypertension
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