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Journal of Hypertension

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https://www.readbyqxmd.com/read/28525406/blood-pressure-among-australian-aboriginal-children
#1
Nicholas Larkins, Armando Teixeira-Pinto, Emily Banks, Hasantha Gunasekera, Alan Cass, Jane Kearnes, Jonathan C Craig
OBJECTIVES: To determine the prevalence of elevated blood pressure (BP) and potential predictors of SBP and DBP in urban Australian aboriginal children. METHODS: The Study of Environment on Aboriginal Resilience and Child Health is a prospective cohort study of urban Aboriginal children attending four Aboriginal Community Controlled Health Services in New South Wales, Australia. Clinical measures included a manual BP measured by research officers using standardized protocols...
May 18, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28520613/uric-acid-and-blood-pressure-exploring-the-role-of-uric-acid-production-in-the-maastricht-study
#2
Lieke E J M Scheepers, Annelies Boonen, Pieter C Dagnelie, Miranda T Schram, Carla J H van der Kallen, Ronald M A Henry, Abraham A Kroon, Coen D A Stehouwer, Ilja C W Arts
OBJECTIVE: Accumulation of reactive oxygen species by increased uric acid production has been suggested as a possible underlying mechanism for the association between uric acid and high blood pressure (BP). We, therefore, investigated the association between serum uric acid concentration 24-h urinary uric acid excretion, as proxy for uric acid production, and ambulatory 24-h BP and hypertension. METHODS: Cross-sectional analyses were conducted among 2555 individuals [52% men, mean age 60...
May 17, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28520612/guidelines-on-the-management-of-arterial-hypertension-and-related-comorbidities-in-latin-america
#3
(no author information available yet)
No abstract text is available yet for this article.
May 17, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28509722/rationale-for-nebivolol-valsartan-combination-for-hypertension-review-of-preclinical-and-clinical-data
#4
Thomas D Giles, John R Cockcroft, Bertram Pitt, Abhijeet Jakate, Harold M Wright
: To treat hypertension, combining two or more antihypertensive drugs from different classes is often necessary. β-Blockers and renin-angiotensin-aldosterone system inhibitors, when combined, have been deemed 'less effective' based on partially overlapping mechanisms of action and limited evidence. Recently, the single-pill combination (SPC) of nebivolol (Neb) 5 mg - a vasodilatory β1-selective antagonist/β3 agonist - and valsartan 80 mg, an angiotensin II receptor blocker, was US Food and Drug Administration-approved for hypertension...
May 15, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28509727/lower-dementia-risk-with-different-classes-of-antihypertensive-medication-in-older-patients
#5
Tessa van Middelaar, Lonneke A van Vught, Eric P Moll van Charante, Lisa S M Eurelings, Suzanne A Ligthart, Jan W van Dalen, Bert Jan H van den Born, Edo Richard, Pim W A van Gool
OBJECTIVE: Use of antihypertensive medication (AHM) is potentially associated with a reduced risk of dementia. Both calcium channel blockers (CCBs) and angiotensin receptor blockers (ARBs) are suggested to have a more pronounced protective effect. We aimed to study the association between different classes of AHM and dementia in older people. METHODS: A subgroup of community-dwelling older people using AHM included in the 'Prevention of Dementia by Intensive Vascular Care' randomized controlled trial was studied...
May 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28509726/sodium-butyrate-suppresses-angiotensin-ii-induced-hypertension-by-inhibition-of-renal-pro-renin-receptor-and-intrarenal-renin-angiotensin-system
#6
Lei Wang, Qing Zhu, Aihua Lu, Xiaofen Liu, Linlin Zhang, Chuanming Xu, Xiyang Liu, Haobo Li, Tianxin Yang
OBJECTIVES: Butyrate, a short-chain fatty acid, is the end product of the fermentation of complex carbohydrates by the gut microbiota. Recently, sodium butyrate (NaBu) has been found to play a protective role in a number of chronic diseases. However, it is still unclear whether NaBu has a therapeutic potential in hypertension. The present study was aimed to investigate the role of NaBu in angiotensin II (Ang II)-induced hypertension and to further explore the underlying mechanism. METHODS: Ang II was infused into uninephrectomized Sprague-Dawley rats with or without intramedullary infusion of NaBu for 14 days...
May 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28509725/telmisartan-and-hydrochlorothiazide-antihypertensive-treatment-in-high-sodium-intake-population-a-randomized-double-blind-trial
#7
Puhong Zhang, Hongyi Wang, Lei Sun, Jing Zhang, Yang Xi, Yangfeng Wu, Lijing L Yan, Xian Li, Ningling Sun
OBJECTIVES: To compare the blood pressure (BP)-lowering effects of telmisartan 40 mg/day and hydrochlorothiazide (HCTZ) 25 mg/day in high sodium intake patients with mild-to-moderate hypertension in China. METHODS: In this randomized, double-blind trial, eligible patients were randomly divided into telmisartan and HCTZ groups with three follow-ups scheduled on days 15, 30, and 60 after enrollment to compare BP decrease, hypokalemia, and other adverse events after intervention...
May 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28509724/associations-between-glycaemic-deterioration-and-aortic-stiffness-and-central-blood-pressure-the-addition-pro-study
#8
Nanna B Johansen, Signe S Rasmussen, Niels Wiinberg, Dorte Vistisen, Marit E Jørgensen, Erling B Pedersen, Torsten Lauritzen, Annelli Sandbæk, Daniel R Witte
OBJECTIVES: In the context of screening for diabetes, we examined levels of central haemodynamics among individuals with different levels of diabetes risk and analysed the impact of glycated haemoglobin A (HbA1c) and HbA1c changes on central haemodynamics. METHODS: A Danish population-based stepwise screening programme for diabetes including a diabetes risk score (DRS) questionnaire and glucose measurements identified seven groups of individuals at increasing levels of diabetes risk...
May 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28509723/determinants-of-retinal-microvascular-features-and-their-relationships-in-two-european-populations
#9
Mirna Kirin, Reka Nagy, Thomas J MacGillivray, Ozren Polašek, Caroline Hayward, Igor Rudan, Harry Campbell, Sarah Wild, Alan F Wright, James F Wilson, Veronique Vitart
OBJECTIVES: To examine factors influencing retinal vasculature in two environmentally contrasted, cross-sectional studies of adult participants of European descent and to estimate the extent and specificity of genetic contributions to each retinal vasculature feature. METHODS: Retinal images from 1088 participants in the Orkney Complex Disease Study and 387 in the CROATIA-Korčula study, taken using the same nonmydriatic camera system and graded by the same person, were evaluated...
May 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28505066/routine-urinary-detection-of-antihypertensive-drugs-for-systematic-evaluation-of-adherence-to-treatment-in-hypertensive-patients
#10
Idir Hamdidouche, Vincent Jullien, Pierre Boutouyrie, Eliane Billaud, Michel Azizi, Stéphane Laurent
BACKGROUND: Nonadherence to antihypertensive therapy is an important cause of poor blood pressure control. However, to date, few effective and accurate tools exist to routinely evaluate drug nonadherence. METHODS: In this observational study, performed under conditions of routine clinical practice, we included 174 patients (aged 67 ± 11 years) with treated essential hypertension who attended the outpatient hypertension clinic of a university hospital. Adherence to antihypertensive treatment was measured by using ultraperformance liquid chromatography-tandem mass spectrometry in spot urine at the time of clinical appointment and blood pressure measurement...
May 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28505065/arterial-reservoir-characteristics-and-central-to-peripheral-blood-pressure-amplification-in-the-human-upper-limb
#11
Xiaoqing Peng, Martin G Schultz, Dean S Picone, J Andrew Black, Nathan Dwyer, Philip Roberts-Thomson, Justin E Davies, James E Sharman
BACKGROUND: Arterial reservoir characteristics are related to blood pressure (BP) and independently predict cardiovascular events. It is unknown if arterial reservoir characteristics are modified from the central-to-peripheral large arteries and whether there is a contributory role to BP amplification. The aim of this study was to assess central-to-peripheral changes in arterial reservoir characteristics and determine associations with BP. METHODS: Reservoir pressure (RP) and excess pressure (XSP) were derived from intra-arterial BP waveforms among 51 participants (aged 63 ± 13 years, 63% men) undergoing clinically indicated cardiac angiography...
May 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28505064/changes-in-renal-artery-dimensions-are-associated-with-clinical-response-to-radiofrequency-renal-denervation-a-series-of-studies-using-quantitative-angiography-and-intravascular-ultrasound
#12
Thomas Weber, Jörg Kellermair, Karen T Witberg, Jurgen Ligthart, Robert J Melder, Thomas Forstner, Bernd Eber
OBJECTIVE: Renal denervation (RDN) can cause focal (notches) and global (spasms) changes in renal artery dimensions. We quantified these changes and related them to renal norepinephrin tissue content in animals and to blood pressure (BP) changes in patients. METHODS: We measured renal artery dimensions pre-RDN and post-RDN, utilizing quantitative renal angiography (QRA) in a porcine model and in a retrospective patient cohort, and intravascular ultrasound (IVUS) in a prospective patient cohort...
May 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28505063/retinal-vessel-metrics-normative-data-and-their-use-in-systemic-hypertension-results-from-the-gutenberg-health-study
#13
Katharina A Ponto, David J Werner, Linn Wiedemer, Dagmar Laubert-Reh, Alexander K Schuster, Stefan Nickels, René Höhn, Andreas Schulz, Harald Binder, Manfred Beutel, Karl J Lackner, Philipp S Wild, Norbert Pfeiffer, Alireza Mirshahi
PURPOSE OF REVIEW: In-vivo measurement of retinal vascular calibers may be used as a tool to study the pathophysiology and clinical status of the microvasculature of the retina. The aim of this study was to generate normative data for retinal vessel parameters, and to evaluate the clinical relevance in systemic hypertension. METHODS: Fundus photographs from 4309 participants of the Gutenberg Health Study were assessed using the 'retinal vessel analyzer' software (IMEDOS)...
May 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28505062/relationships-between-depression-and-anxiety-symptoms-scores-and-blood-pressure-in-young-adults
#14
Sunil K Bhat, Lawrence J Beilin, Monique Robinson, Sally Burrows, Trevor A Mori
BACKGROUND: Depression and anxiety are risk factors for cardiovascular disease, but their relationship to blood pressure (BP) is less clear. Age-related comorbidity and lifestyle factors may confound these relationships. This study aimed to assess the relationships among BP, depression and anxiety symptom scores and self-reported history of depression in young adults. METHOD: Data on 1014 participants aged 20 years from the Western Australian Cohort (Raine) Study were analyzed for cross-sectional associations between clinic BP and Depression, Anxiety, Stress Scale questionnaire scores or a reported history of depression, accounting for relevant confounders...
May 12, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28486271/withdrawal-of-antihypertensive-medication-a-systematic-review
#15
Veronika van der Wardt, Jennifer K Harrison, Tomas Welsh, Simon Conroy, John Gladman
: Although antihypertensive medication is usually continued indefinitely, observations during wash-out phases in hypertension trials have shown that withdrawal of antihypertensive medication might be well tolerated to do in a considerable proportion of people. A systematic review was completed to determine the proportion of people remaining normotensive for 6 months or longer after cessation of antihypertensive therapy and to investigate the safety of withdrawal. The mean proportion adjusted for sample size of people remaining below each study's threshold for hypertension treatment was 0...
May 9, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28486272/blood-pressure-heart-rate-and-double-product-in-a-pooled-cohort-the-japan-arteriosclerosis-longitudinal-study
#16
Kei Asayama, Atsushi Hozawa, Masataka Taguri, Takayoshi Ohkubo, Yasuharu Tabara, Kazuo Suzuki, Takashi Ando, Akiko Harada, Yasuo Ohashi, Hirotsugu Uechima, Hideaki Toyoshima, Yutaka Imai
OBJECTIVE: To identify the characteristics of blood pressure (BP), heart rate (HR), and double product in a Japanese population sample. METHODS: We pooled individual records from 1999 to 2005 for 111 007 participants in 25 community-based cohorts and seven worksite-based cohorts. The data were analyzed to provide information on BP, HR, and double product according to age-sex groups and use of antihypertensive medication. RESULTS: Average BP was 130/77 mmHg among men and women combined...
May 8, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28486270/prevalence-awareness-treatment-and-control-of-hypertension-in-four-middle-east-countries
#17
Afzalhussein M Yusufali, Rasha Khatib, Shofiqul Islam, Khalid F Alhabib, Ahmad Bahonar, Hani M Swidan, Umaiyeh Khammash, Mostafa Q Alshamiri, Sumathy Rangarajan, Salim Yusuf
OBJECTIVE: We report the prevalence, awareness, treatment, and control of hypertension across four Middle Eastern countries (Iran, Occupied Palestinian Territory, Saudi Arabia, and United Arab Emirates), using a standardized and uniform method. METHODS: The Prospective Urban Rural Epidemiology study enrolled participants from 52 urban and 35 rural communities from four countries in the Middle East. We report results using definitions of hypertension, prevalence, awareness, treatment, and control, and the standards for uniform reporting of hypertension in adults as recently recommended by the World Hypertension League expert committee...
May 8, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28306636/blood-pressure-lowering-efficacy-and-safety-of-perindopril-indapamide-amlodipine-single-pill-combination-in-patients-with-uncontrolled-essential-hypertension-a-multicenter-randomized-double-blind-controlled-trial
#18
Jean-Jacques Mourad, Celso Amodeo, Martine de Champvallins, Romualda Brzozowska-Villatte, Roland Asmar
OBJECTIVES: This 4-month, double-blind, randomized, controlled trial was designed to demonstrate the superiority of perindopril/indapamide/amlodipine single pill over perindopril/indapamide after 1 month and to determine further up-titration efficacy and safety in patients with mild-to-moderate hypertension. METHODS: After a 1-month run-in period on perindopril/indapamide 5/1.25 mg, patients with SBP/DBP at least 150/95 mmHg and no diabetes or renal insufficiency received perindopril/indapamide/amlodipine 5/1...
May 2, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28463913/therapeutic-approaches-age-and-ethnicity-in-hypertension
#19
Alberto Zanchetti
No abstract text is available yet for this article.
May 1, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28448291/the-polypill-in-cardiovascular-prevention-evidence-limitations-and-perspective-position-paper-of-the-european-society-of-hypertension
#20
Antonio Coca, Enrico Agabiti-Rosei, Renata Cifkova, Athanasios J Manolis, Josep Redón, Giuseppe Mancia
: Antihypertensive, lipid lowering, antidiabetic and antiplatelet treatments all substantially reduce the risk of cardiovascular morbid and fatal events. In real life, however, effective implementation of these treatments is rare, and thus their contribution to cardiovascular prevention is much less than it could be, based on research data. This article reviews the pros and cons of cardiovascular prevention by the polypill approach. It is argued that the high prevalence of individuals with a multifactorial risk profile provides a strong rationale for a therapeutic strategy based on the combination in a single tablet of drugs against different risk factors...
April 26, 2017: Journal of Hypertension
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