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Journal of Hypertension

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https://www.readbyqxmd.com/read/28426443/independency-of-the-cardio-ankle-vascular-index-from-blood-pressure-at-the-time-of-measurement
#1
Kohji Shirai, Kazuhiro Shimizu, Masanobu Takata, Kenji Suzuki
No abstract text is available yet for this article.
April 19, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28410304/diagnostic-rate-of-primary-aldosteronism-in-emilia-romagna-northern-italy-during-16-years-2000-2015
#2
Ermanno Rossi, Franco Perazzoli, Aurelio Negro, Antonia Magnani
BACKGROUND: Although primary aldosteronism is considered the most common form of endocrine hypertension, the diagnostic rate of primary aldosteronism in the territory is unknown. OBJECTIVES: The aims of the current study were to compare the number of patients discharged with International Classification of Diseases 9 Clinical Modification codes compatible with primary aldosteronism from all the hospitals in Emilia-Romagna during 16 years (from 2000 to 2015) with the number of expected cases of primary aldosteronism, and to compare the number of patients with primary aldosteronism who underwent adrenalectomy in the period 2000-2015 with the number of expected cases of unilateral primary aldosteronism...
April 13, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28403043/plasma-galectin-3-concentrations-in-patients-with-primary-aldosteronism
#3
T N A Daniëlle van den Berg, Wouter C Meijers, A Rogier T Donders, Antonius E Van Herwaarden, Gerard A Rongen, Rudolf A de Boer, Jaap Deinum, Niels P Riksen
BACKGROUND: The incidence of cardiovascular events is higher in patients with primary aldosteronism than in patients with essential hypertension (EHT), despite similar blood pressure levels. This suggests detrimental cardiovascular effects of aldosterone. Amongst others, it has been suggested that galectin-3 (Gal-3) is a key mediator in aldosterone-induced myocardial fibrosis. OBJECTIVE: We studied whether patients with primary aldosteronism have higher plasma Gal-3 concentrations than patients with EHT and evaluated its reversibility after adrenalectomy...
April 11, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28403042/altered-mitochondrial-function-capacitative-calcium-entry-and-contractions-in-the-aorta-of-hypertensive-rats
#4
Iago Méndez-López, Guilherme H S Bomfim, Diego C Musial, Juan A Arranz-Tagarro, Juan P Velasco-Martín, Javier Regadera, Neide H Jurkiewicz, Aron Jurkiewicz, Antonio G García, Fernando J Padín
OBJECTIVE: It has been suggested that Ca entry through store-operated Ca channels (SOCs) is regulated by a dynamic interplay between the endoplasmic reticulum Ca stores and the mitochondria. These relationships drive the activation and inactivation of SOCs, yet it remains unclear whether this regulation of SOCs by mitochondria is altered in the aorta of spontaneously hypertensive rats (SHRs). METHODS: We performed a thorough study of the mitochondrial membrane potential, the ability of mitochondria to deal with cytosolic Ca, capacitative Ca entry (CCE), and stromal interaction molecule 1 (STIM1) and calcium release-activated calcium modulator 1 (orai1) protein expression, as well as the contractile capacity of aortic rings, in normotensive Wistar Kyoto rats (WKYs) and SHRs...
April 11, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28403041/sex-differences-in-time-trends-of-blood-pressure-among-swedish-septuagenarians-examined-three-decades-apart-a-longitudinal-population-study
#5
Erik Joas, Xinxin Guo, Silke Kern, Svante Östling, Ingmar Skoog
OBJECTIVE: The aim of this study was to analyze the influence of birth cohort, sex and age on the trajectories of SBP and DBP in two birth cohorts of 70-year-olds, examined 3 decades apart and followed up at ages 75 and 79-80 years. METHODS: Two population samples of 70-year-olds from Gothenburg, Sweden, were examined. The first, born in 1901-1902, was examined in 1971-1972 (n = 973). The second, born in 1930, was examined in 2000 (n = 509). Both samples were re-examined at ages 75 and 79-80 years...
April 11, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28399045/a-differential-expression-of-uncoupling-protein-2-associates-with-renal-damage-in-stroke-resistant-spontaneously-hypertensive-rat-stroke-prone-spontaneously-hypertensive-rat-derived-stroke-congenic-lines
#6
Speranza Rubattu, Maria Cotugno, Franca Bianchi, Luigi Sironi, Paolo Gelosa, Rosita Stanzione, Maurizio Forte, Claudia De Sanctis, Michele Madonna, Simona Marchitti, Alice Pignieri, Sebastiano Sciarretta, Massimo Volpe
OBJECTIVES: Uncoupling protein-2 (UCP2), a mitochondrial anion transporter involved in mitochondrial uncoupling, limiting reactive oxygen species formation, is significantly downregulated in kidneys of high-salt-fed stroke-prone spontaneously hypertensive rat (SHRSP), where it associates with increased renal damage occurrence. METHODS: We aimed at establishing whether UCP2 differential expression associates with renal damage in two stroke-resistant spontaneously hypertensive rat (SHRSR)/SHRSP-derived stroke congenic lines...
April 10, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28399044/red-meat-consumption-and-cardiovascular-target-organ-damage-from-the-strong-heart-study
#7
Bernhard Haring, Wenyu Wang, Amanda Fretts, Daichi Shimbo, Elisa T Lee, Barbara V Howard, Mary J Roman, Richard B Devereux
OBJECTIVE: The aim of this study was to investigate whether red meat consumption is related to changes in left ventricular mass (LVM), left atrial diameter and carotid atherosclerosis in American Indians. METHODS: We prospectively analyzed echocardiographic and carotid ultrasound data of 1090 adults aged 40 years and older enrolled in the Strong Heart Family Study who were free of cardiovascular disease at baseline - 535 (49%) were hypertensive and 555 (51%) participants were nonhypertensive...
April 10, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28399043/different-estimation-methods-of-spontaneous-baroreflex-sensitivity-have-different-predictive-value-in-heart-failure-patients
#8
Gian Domenico Pinna, Alberto Porta, Roberto Maestri, Beatrice De Maria, Laura Adelaide Dalla Vecchia, Maria Teresa La Rovere
OBJECTIVE: Several methods have been developed so far to estimate cardiac baroreflex sensitivity (BRS) through the analysis of spontaneous fluctuations of systolic arterial pressure (SAP) and R-R interval. Their relative performance in predicting cardiac mortality in heart failure patients is not known. The aim of this study was to compare the prognostic value of a set of representative indexes of spontaneous BRS in these patients. METHODS: We studied 228 stable, moderate-to-severe heart failure patients with reduced ejection fraction, in sinus rhythm, who underwent an 8-min supine recording of ECG, arterial blood pressure and respiration during paced breathing (15 breaths/min)...
April 10, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28399042/pre-end-stage-renal-disease-visit-to-visit-systolic-blood-pressure-variability-and-post-end-stage-renal-disease-mortality-in-incident-dialysis-patients
#9
Keiichi Sumida, Miklos Z Molnar, Praveen K Potukuchi, Fridtjof Thomas, Jun Ling Lu, Kunihiro Yamagata, Kamyar Kalantar-Zadeh, Csaba P Kovesdy
OBJECTIVES: Higher SBP visit-to-visit variability (SBPV) has been associated with increased risk of adverse events in patients with chronic kidney disease, but the association of SBPV in advanced nondialysis-dependent chronic kidney disease with mortality after the transition to end-stage renal disease (ESRD) remains unknown. METHODS: Among 17 729 US veterans transitioning to dialysis between October 2007 and September 2011, we assessed SBPV calculated from the SD of at least three intraindividual outpatient SBP values during the last year prior to dialysis transition (prelude period)...
April 10, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28399041/accuracy-of-transthoracic-echocardiography-in-the-assessment-of-proximal-aortic-diameter-in-hypertensive-patients-comparison-with-cardiac-magnetic-resonance
#10
Dario Leone, Francesco Tosello, Riccardo Faletti, Giulia Schivazappa, Giulia Bruno, Eleonora Avenatti, Agnese Ravera, Franco Veglio, Alberto Milan
BACKGROUND: Accurate and reproducible measurements of proximal thoracic aorta diameters are essential in the diagnosis and follow-up of patients with aortic dilatation, a condition particularly common in hypertensive patients. AIM: to evaluate the accuracy of transthoracic echocardiography (TTE) in comparison with cardiac magnetic resonance (CMR) for the assessment of proximal thoracic aorta diameters in a cohort of hypertensive patients. METHODS: A total of 75 essential hypertensive outpatients previously evaluated by TTE and than by CMR were included in the study...
April 10, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28379892/evaluation-of-arterial-stiffness-by-finger-toe-pulse-wave-velocity-optimization-of-signal-processing-and-clinical-validation
#11
Hasan Obeid, Hakim Khettab, Louise Marais, Magid Hallab, Stéphane Laurent, Pierre Boutouyrie
BACKGROUND: Carotid-femoral pulse wave velocity (PWV) (cf-PWV) is the gold standard for measuring aortic stiffness. Finger-toe PWV (ft-PWV) is a simpler noninvasive method for measuring arterial stiffness. Although the validity of the method has been previously assessed, its accuracy can be improved. ft-PWV is determined on the basis of a patented height chart for the distance and the pulse transit time (PTT) between the finger and the toe pulpar arteries signals (ft-PTT). METHOD: The objective of the first study, performed in 66 patients, was to compare different algorithms (intersecting tangents, maximum of the second derivative, 10% threshold and cross-correlation) for determining the foot of the arterial pulse wave, thus the ft-PTT...
April 4, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28379891/relationship-between-plasma-plasminogen-activator-inhibitor-1-and-hypertension-in-american-indians-findings-from-the-strong-heart-study
#12
Hao Peng, Fawn Yeh, Giovanni de Simone, Lyle G Best, Elisa T Lee, Barbara V Howard, Jinying Zhao
OBJECTIVES: Deficient plasminogen activator inhibitor-1 (PAI-1) prevented hypertension in mice. Plasma PAI-1 was associated with hypertension in cross-sectional analyses, but the prospective association of PAI-1 with incident hypertension in large epidemiological studies is scarce. METHODS: Leveraging two longitudinal cohorts of American Indians in the Strong Heart Study (SHS, N = 1019) and the Strong Heart Family Study (SHFS, N = 1502), we examined the prospective association of plasma PAI-1 with incident hypertension by multivariate logistic regression, adjusting for age, sex, study site, smoking, drinking, dietary sodium, obesity, lipids, fasting glucose, kidney function, inflammation, and follow-up years...
April 4, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28379890/morning-blood-pressure-monitoring-in-the-management-of-hypertension
#13
Ji-Guang Wang, Kazuomi Kario, Jeong-Bae Park, Chen-Huan Chen
: The aim of the current article is to review the current evidence on the role of morning blood pressure (BP) in the management of hypertension. Morning BP surge had been and will continue to be a hot topic of hypertension research. However, more evidence is needed to prove its clinical usefulness in the management of hypertension. Masked morning hypertension, as the other forms of masked hypertension, requires more research. The concept of morning BP monitoring could be clinically relevant in the therapeutic management of hypertension and in the prevention of cardiovascular complications by defining and treating morning hypertension...
April 4, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28362679/blood-pressure-and-risk-of-breast-cancer-overall-and-by-subtypes-a-prospective-cohort-study
#14
Yi Yang, Brigid M Lynch, Allison M Hodge, Danny Liew, Catriona A Mclean, Mathias Seviiri, Melissa C Southey, John L Hopper, Dallas R English, Graham G Giles, Roger L Milne, Pierre-Antoine Dugué
OBJECTIVE: Blood pressure (BP) and breast cancer may share a common pathophysiologic pathway involving chronic inflammation, hormone synthesis and metabolism. Previous studies investigating the association between BP and breast cancer measured BP at a single time point and did not examine associations by breast cancer molecular subtypes. METHODS: We used data from 22 833 female participants in the Melbourne Collaborative Cohort Study. BP was objectively measured at baseline (1990-1994) and a follow-up visit (2003-2007)...
March 30, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28350577/reliability-of-heart-rate-as-neuroadrenergic-marker-in-the-metabolic-syndrome
#15
Fosca Quarti Trevano, Gino Seravalle, Mario Macchiarulo, Paolo Villa, Carlo Valena, Raffaella Dell'Oro, Giuseppe Mancia, Guido Grassi
BACKGROUND: Metabolic syndrome is characterized by a pronounced sympathetic overactivity as documented by the marked increase in muscle sympathetic nerve traffic (MSNA) as well as in plasma norepinephrine values reported in this condition. Whether and to what extent heart rate (HR) reflects the abovementioned adrenergic alterations in metabolic syndrome remains largely undefined. It is also undefined the validity of the abovementioned adrenergic markers in reflecting the main features of the metabolic syndrome...
March 27, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28350576/absence-of-resting-cardiovascular-dysfunction-in-middle-aged-endurance-trained-athletes-with-exaggerated-exercise-blood-pressure-responses
#16
Katharine D Currie, Ryan T Sless, Catherine F Notarius, Scott G Thomas, Jack M Goodman
OBJECTIVE: Untrained individuals with exaggerated blood pressure (EBP) responses to graded exercise testing are characterized as having resting dysfunction of the sympathetic and cardiovascular systems. The purpose of this study was to determine the resting cardiovascular state of endurance-trained individuals with EBP through a comparison of normotensive athletes with and without EBP. METHODS: EBP was defined as a maximal systolic blood pressure (SBP) at least 190 mmHg and at least 210 mmHg for women and men respectively, in response to a graded exercise test...
March 27, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28350575/influence-of-carotid-atherosclerotic-plaques-on-pulse-wave-assessment-with-arterial-tonometry
#17
Andrea Grillo, Giulia Simon, Paolo Salvi, Matteo Rovina, Corrado Baldi, Ilaria Prearo, Stella Bernardi, Bruno Fabris, Andrea Faini, Gianfranco Parati, Moreno Bardelli, Renzo Carretta
OBJECTIVE: Aortic stiffness and central pressure measurements have become increasingly important for the overall estimation of cardiovascular risk. The aim of this study is to verify whether the presence of stenosis in the carotid arteries due to atherosclerotic plaques may induce a bias in the measurement of carotid-femoral pulse wave velocity (PWV) and in the analysis of central pulse waveform variables assessed by carotid tonometry. METHODS: Eighty-four patients (age: 67...
March 27, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28346241/hemodynamic-responses-to-magnetic-stimulation-of-carotid-sinus-in-normotensive-rabbits
#18
Jun Zhang, Qinqin Cao, Rongrong Li, Jingze Hu, Jiafei Dai, Hao Zhang, Huaiming Wang, Fang Yang, Ruidong Ye, Xinfeng Liu, Gelin Xu
OBJECTIVES: Carotid baroreflex plays a crucial role in regulating arterial pressure. Based on this knowledge, electrical stimulation of carotid sinus was designed for treating resistant hypertension. However, the clinical implication of electrical stimulation of carotid sinus is largely restrained due to obvious invasiveness. This study aimed to evaluate the efficacy of magnetic stimulation of carotid sinus (MSCS), a noninvasive strategy, for lowering blood pressure in rabbits. METHODS: MSCS with graded intensities and frequencies were systematically attempted in normotensive rabbits...
March 24, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28319599/treatment-adherence-and-hypertension-in-the-elderly
#19
Alberto Zanchetti
No abstract text is available yet for this article.
March 17, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28319598/allium-vegetable-intakes-and-the-incidence-of-cardiovascular-disease-hypertension-chronic-kidney-disease-and-type-2-diabetes-in-adults-a-longitudinal-follow-up-study
#20
Zahra Bahadoran, Parvin Mirmiran, Amir A Momenan, Fereidoun Azizi
OBJECTIVES: This study investigated the association between habitual consumption of allium vegetables (garlic and onion) and the incidence of cardiovascular disease (CVD) outcomes, hypertension (HTN), chronic kidney disease (CKD), and type 2 diabetes (T2D). METHODS: Adult men and women, participated in the Tehran Lipid and Glucose Study (2006-2008 to 2012-2014), were recruited. Habitual dietary intakes were assessed using a validated semiquantitative food frequency questionnaire...
March 17, 2017: Journal of Hypertension
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