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Journal of Hypertension

Kenichi Matsushita, Kazumasa Harada, Tetsuro Miyazaki, Takamichi Miyamoto, Shun Kohsaka, Kiyoshi Iida, Shuzou Tanimoto, Makoto Takei, Toru Hosoda, Yoshiya Yamamoto, Yasuyuki Shiraishi, Hideaki Yoshino, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama
OBJECTIVE: No agents have been proven to improve survival in heart failure with preserved ejection fraction (HFpEF), but the phenotypic diversity of HFpEF suggests it may be possible to identify specific HFpEF phenotypes that will benefit from certain treatments. This study compared the risk factors for and prognostic impacts of treatments on in-hospital mortality between HFpEF patients with (+) and without (-) high blood pressure (HBP). METHODS: Data on 2238 consecutive HFpEF patients were extracted from Tokyo CCU Network data registry and analysed...
September 17, 2018: Journal of Hypertension
Sarah L Stevens, Richard J McManus, Richard J Stevens
OBJECTIVES: Blood pressure (BP) is a long-established risk factor for cardiovascular disease (CVD). SBP is used in all widely used cardiovascular risk scores for clinical decision-making. Recently, within-person BP variability has been shown to be a major predictor of CVD. We investigated whether cardiovascular risk scores could be improved by incorporating BP variability with standard risk factors. METHODS: We used cohort data on patients aged 40-74 on 1 January 2005, from English general practices contributing to the Clinical Practice Research Datalink, a research database derived from electronic health records...
September 17, 2018: Journal of Hypertension
Xiaohua Liang, Shaoyong Su, Guang Hao, Harold Snieder, Frank Treiber, Gaston Kapuku, Xiaoling Wang
OBJECTIVE: Increased arterial stiffness measured by pulse wave velocity (PWV) has been shown to be an important parameter of cardiovascular risk. Longitudinal development of PWV from youth to early adulthood and its possible sociodemographic, anthropometric, hemodynamic and behavioral moderators will be illustrated. METHODS: Individual growth curves of carotid-distal PWV across age were created for 559 African American and European American men and women with a maximum of five assessments over an average of 7-year follow-up (mean age at participants' first assessment, 22...
September 17, 2018: Journal of Hypertension
Xiaoxiao Wen, Long Zhou, Jeremiah Stamler, Queenie Chan, Linda Van Horn, Martha L Daviglus, Alan R Dyer, Paul Elliott, Hirotsugu Ueshima, Katsuyuki Miura, Nagako Okuda, Yangfeng Wu, Liancheng Zhao
OBJECTIVE: The present study aims to compare 24-h dietary recalls with 24-h urine collections for the estimation of sodium intake at both population and individual levels in China, Japan, the United Kingdom (UK), and the United States of America (USA), using data from the International Study of Macro- and Micro-nutrients and Blood Pressure (INTERMAP). METHODS: Mean differences between 24-h dietary recalls and 24-h urine collections were calculated for their agreement in estimating sodium intake at the population level; relative and absolute differences as well as misclassification of salt intake groups (salt intake <6, 6-8...
September 17, 2018: Journal of Hypertension
Andrea Kolkenbeck-Ruh, Angela J Woodiwiss, Ravi Naran, Eitzaz Sadiq, Chanel Robinson, Tshegofatso H Motau, Taalib Monareng, Philanathi Mabena, Nomvuyo Manyatsi, Pitchou Z Gazwa, Talib Abdool-Carrim, Olebogeng H I Majane, Martin Veller, Girish Modi, Gavin R Norton
AIM: Although chronic kidney disease (CKD) as determined from estimated glomerular filtration rate (eGFR) is recommended for risk prediction by current hypertension guidelines, the equations to derive eGFR may not perform well in black Africans. We compared whether across the adult lifespan, eGFR or CKD are as closely associated with noncardiac arterial vascular events, as carotid intima-media thickness (IMT), in Africa. METHODS: In 1152 black South Africans [480 with noncardiac arterial events (294 with critical lower limb ischemia, 186 with stroke) of which 37% were premature] and 672 age, sex and ethnicity-matched controls from a randomly selected community sample, we assessed relations between eGFR, CKD or carotid IMT (B-mode ultrasound) and arterial events...
September 17, 2018: Journal of Hypertension
Yi-Chen Yu, Ying Jiang, Meng-Meng Yang, Sai-Nan He, Xia Xi, Ye-Tao Xu, Wen-Sheng Hu, Qiong Luo
BACKGROUND: Increasing epidemiological studies have confirmed the association between maternal preeclampsia and elevated blood pressure in their offspring. Though case-control or cohort studies have demonstrated long-term outcomes for the offspring of preeclampsia, it is still a question that how these changes were caused by genetic reasons or by preeclampsia itself. OBJECTIVE: In our study, we explored the potential epigenetic regulation of delta-like homolog 1-maternally expressed gene 3 (DLK1-MEG3) region in human umbilical vein endothelial cells (HUVECs), and its connection with endothelium-derived factors...
September 17, 2018: Journal of Hypertension
Edoardo Sciatti, Rossana Orabona, Federico Prefumo, Enrico Vizzardi, Ivano Bonadei, Adriana Valcamonico, Marco Metra, Tiziana Frusca
OBJECTIVE: To compare the elastic properties of the ascending aorta and ventricular-arterial coupling (VAC) in women with a previous pregnancy complicated by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome, women who experienced preeclampsia, and healthy controls. METHODS: Women with a history of preeclampsia (n = 60) or HELLP syndrome (n = 49) and matched healthy controls (n = 60) underwent transthoracic echocardiography at 6 months to 4 years after delivery...
September 17, 2018: Journal of Hypertension
Jone Vencloviene, Abdonas Tamosiunas, Ricardas Radisauskas, Dalia Luksiene, Vidmantas Vaiciulis, Gailute Bernotiene, Martin Bobak
AIM: to detect the complex association between arterial blood pressure (BP) and air temperature, atmospheric pressure, relative humidity, wind speed, and North Atlantic oscillation (NAO) indices. METHODS: Data were obtained from the survey performed in the framework of the international Health, Alcohol and Psychosocial Factors in Eastern Europe study. The number of individuals used in the models or other analysed groups was 7077. The association between environmental variables and SBP and DBP were evaluated by applying the multiple regression analysis, adjusting for health-related and weather variables...
September 17, 2018: Journal of Hypertension
Allison L Kuipers, Iva Miljkovic, Emma Barinas-Mitchell, Ryan Cvejkus, Clareann H Bunker, Victor W Wheeler, Joseph M Zmuda
OBJECTIVE: African ancestry individuals are at high risk for hypertensive cardiovascular disease (CVD) and could benefit from early detection of arterial stiffening. We tested the association between the 2017 ACC/AHA hypertension categorizations, which include new blood pressure (BP) cutoffs and a definition for elevated BP, and arterial stiffness in 772 Afro-Caribbean men aged 50+ years (mean 64 years). METHODS: Arterial stiffness was assessed by brachial-ankle pulse-wave velocity (PWV) using a waveform analyzer...
September 17, 2018: Journal of Hypertension
Frédérique Thomas, Bruno Pannier, Nicolas Danchin, Michel E Safar
OBJECTIVES: Although the links between pulsatile hemodynamics and age are widely acknowledged in hypertension, the interactions of sex, ethnicity, and metabolic factors with hemodynamic parameters remain largely unknown. We investigated the effects of body weight, glycemia, and cholesterolemia on the carotid augmentation index (CAI) and potential changes over time, with particular focus on the roles of sex and ethnicity. METHODS: Baseline (V1) and repeat (V2) measurements (at ∼1...
September 17, 2018: Journal of Hypertension
Haruki Momma, Susumu S Sawada, Robert A Sloan, Yuko Gando, Ryoko Kawakami, Motohiko Miyachi, Yasushi Fukunaka, Takashi Okamoto, Koji Tsukamoto, Ryoichi Nagatomi, Steven N Blair
OBJECTIVES: Although maintaining cardiorespiratory fitness is encouraged to reduce the risk of hypertension, the level at, and length of time for which, individuals need to maintain fitness remains unclear. We examined the association between the frequency of achieving the recommended fitness levels of the 'Physical Activity Reference for Health Promotion 2013' and the risk of hypertension among Japanese men. METHODS: This cohort study was conducted in 6653 men without hypertension enrolled in 1986...
September 17, 2018: Journal of Hypertension
Dean S Picone, Martin G Schultz, Xiaoqing Peng, J Andrew Black, Nathan Dwyer, Philip Roberts-Thomson, Ahmad Qasem, James E Sharman
OBJECTIVE: Estimation of aortic blood pressure (BP) requires peripheral BP waveform calibration. Mean arterial pressure (MAP)/DBP calibration is purported to estimate aortic BP more accurately than SBP/DBP calibration. However, this is based on inaccurate cuff calibration. Thus, direct comparisons of each calibration method using intra-arterial BP are required to confirm this, and was the aim of this study. METHODS: Ascending aortic, brachial and radial artery intra-arterial BPs were measured among 107 patients (61...
September 17, 2018: Journal of Hypertension
Lisanne A Gitsels, Elena Kulinskaya, Ilyas Bakbergenuly, Nicholas Steel
OBJECTIVE: Compare outcomes of intensive treatment of SBP to less than 120 mmHg versus standard treatment to less than 140 mmHg in the US clinical Systolic Blood Pressure Intervention Trial (SPRINT) with similar hypertensive patients managed in routine primary care in the United Kingdom. METHODS: Hypertensive patients aged 50-90 without diabetes or chronic kidney disease (CKD) were selected in SPRINT and The Health Improvement Network (THIN) database. Patients were enrolled in 2010-2013 and followed-up to 2015 (SPRINT N = 4112; THIN N = 8631)...
September 17, 2018: Journal of Hypertension
Davide Soranna, Antonella Zambon, Giovanni Corrao, Alberto Zanchetti, Gianfranco Parati, Giuseppe Mancia
OBJECTIVE: Office and ambulatory blood pressure (BP) measurements are the main techniques to detect the effects of antihypertensive treatments in clinical trials, but the treatment-induced changes in these BP values can differ markedly. We performed a meta-analysis of clinical trials to quantify these differences and identified some of the associated factors. METHODS: We conducted a MEDLINE search for randomized clinical trials (RCTs) on hypertensive patients treated with at least one antihypertensive drug that reported changes in both office and 24-h BP...
September 17, 2018: Journal of Hypertension
Esther Sapiña-Beltrán, Fernando Santamaria-Martos, Ivan Benítez, Gerard Torres, Juan F Masa, Manuel Sánchez-de-la-Torre, Ferran Barbé, Mireia Dalmases
BACKGROUND: Continuous positive airway pressure (CPAP) treatment reduces blood pressure (BP) in obstructive sleep apnoea (OSA) and hypertensive patients, but there is a lack of data about the effects of CPAP on the BP in normotensive patients. OBJECTIVE: The aim of the study was to evaluate BP changes in normotensive OSA individuals receiving CPAP treatment. METHODS: We selected 131 normotensive outpatients with an apnoea/hypopnoea index (AHI) greater than 15 events/hour who required CPAP treatment...
September 17, 2018: Journal of Hypertension
Gwang-Sil Kim, Young Sup Byun, Hye Young Lee, In Hyun Jung, Kun Joo Rhee, Byung Ok Kim
OBJECTIVE: An increased inter-arm SBP difference (IASBPD) is associated with mortality and cardiovascular events, as well as peripheral vascular disease, which is attributed to subclavian stenosis. The aim of the present study was to investigate the association between the IASBPD and incident chronic kidney disease (CKD) in the Korean population. METHODS: A retrospective cohort study was performed on 8780 Korean adults without baseline CKD. The bilateral blood pressure was measured sequentially and repeatedly at the first visit...
September 17, 2018: Journal of Hypertension
Nikolaos Koletsos, Konstantina Dipla, Areti Triantafyllou, Eugenia Gkaliagkousi, Vasileios Sachpekidis, Andreas Zafeiridis, Stella Douma
OBJECTIVES: An exaggerated blood pressure (BP) response during dynamic exercise testing has been proposed as an additional screening tool to identify systolic masked hypertension (masked-HYP). However, masked-HYP in young people is often characterized by an elevated DBP. Static/isometric exercise elicits augmented sympathetic stimulation causing greater increases in both SBP and DBP than dynamic exercise. AIMS: To examine whether individuals with masked-HYP exhibit exaggerated BP responses during a submaximal handgrip vs...
September 17, 2018: Journal of Hypertension
Katrina A Taylor, Jonathan D Wiles, Damian A Coleman, Paul Leeson, Rajan Sharma, Jamie M O'Driscoll
OBJECTIVE: Hypertension remains the leading modifiable risk factor for cardiovascular disease. Isometric exercise training (IET) has been shown to be a useful nonpharmacological intervention for reducing resting blood pressure (BP). This study aimed to measure alterations in office BP, ambulatory BP, cardiac autonomic modulation and inflammatory and vascular biomarkers following a programme of IET in unmedicated hypertensive patients. METHODS: Twenty-four unmedicated stage 1 hypertensive patients (age 43...
September 17, 2018: Journal of Hypertension
Shahabeddin Rezaei, Zohreh Mahmoudi, Ali Sheidaei, Zahra Aryan, Negar Mahmoudi, Kimiya Gohari, Moein Yoosefi, Mohammad J Hajipour, Arezou Dilmaghani-Marand, Mojdeh Soleimanzadehkhayat, Ali Gholami, Siamak Mirab Samiee, Ghobad Moradi, Bagher Larijani, Farshad Farzadfar
OBJECTIVE: In Iran, there has been no national report on salt intake based on laboratory measurements so far. Therefore, this study was conducted to measure salt intake among Iranian population at the national level. METHODS: In stepwise approach to conduct a surveillance survey 2016, 18 624 Iranian adults (25 years old and above), as a representative sample of Iranian adult population at national and subnational levels, underwent urine sodium measurement and were included in this study...
September 17, 2018: Journal of Hypertension
Sahrai Saeed, Eva Gerdts, Ulrike Waje-Andreassen, Annette Fromm, Nadia Pristaj, Halvor Naess, Knut Matre
BACKGROUND: Hypertension is highly prevalent in ischemic stroke patients, but less is known about its impact on subclinical left ventricular (LV) dysfunction in such patients. METHODS: Conventional and speckle tracking echocardiography was performed in 276 young (15-44 years) and middle-aged (45-60 years) ischemic stroke patients (mean age 50 ± 9 years, 66% men). Hypertension was defined as a history of hypertension, use of antihypertensive medications, persistently elevated blood pressure (BP) during hospitalization or elevated clinic BP (≥140/90 mmHg) and ambulatory BP (≥130/80 mmHg) at follow-up visits...
September 3, 2018: Journal of Hypertension
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