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Journal of Hypertension

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https://www.readbyqxmd.com/read/30418321/eplerenone-improves-endothelial-function-and-arterial-stiffness-and-inhibits-rho-associated-kinase-activity-in-patients-with-idiopathic-hyperaldosteronism-a-pilot-study
#1
Shinji Kishimoto, Kenji Oki, Tatsuya Maruhashi, Masato Kajikawa, Shogo Matsui, Haruki Hashimoto, Yuji Takaeko, Yasuki Kihara, Kazuaki Chayama, Chikara Goto, Yoshiki Aibara, Farina Mohamad Yusoff, Ayumu Nakashima, Kensuke Noma, James K Liao, Yukihito Higashi
OBJECTIVE: Primary aldosteronism is one of the most common cause of secondary hypertension. It is well known that the incidence of cardiovascular events is higher in patients with primary aldosteronism than in patients with essential hypertension. In a previous study, we showed that aldosterone-producing adenoma is associated with vascular function and structure. The aim of this study was to evaluate the effects of eplerenone on vascular function in the macrovasculature and microvasculature, arterial stiffness and Rho-associated kinase (ROCK) activity in patients with idiopathic hyperaldosteronism (IHA)...
November 9, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30418320/screening-for-orthostatic-hypotension-using-home-blood-pressure-measurements
#2
Antoine Cremer, Anne-Laure Rousseau, Romain Boulestreau, Sophie Kuntz, Christophe Tzourio, Philippe Gosse
OBJECTIVE: Orthostatic hypotension is a common condition associated with adverse cardiovascular and cognitive prognosis. Screening for orthostatic hypotension consists of blood pressure measurements in supine (or sitting) and standing position during clinical consultations. As orthostatic hypotension is a poorly reproducible clinical condition, it is likely that the simple measurement carried out during consultations underestimates the true prevalence of the condition. The objective of this study is, therefore, to determine whether screening for orthostatic hypotension with home blood pressure measurements (HBPM) may improve orthostatic hypotension diagnosis without compromising the quality of the blood pressure readings...
November 9, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30394982/nocturnal-blood-pressure-measured-by-home-devices-evidence-and-perspective-for-clinical-application
#3
Kei Asayama, Takeshi Fujiwara, Satoshi Hoshide, Takayoshi Ohkubo, Kazuomi Kario, George S Stergiou, Gianfranco Parati, William B White, Michael A Weber, Yutaka Imai
Studies using ambulatory blood pressure (BP) monitoring have shown that BP during night-time sleep is a stronger predictor of cardiovascular outcomes than daytime ambulatory or conventional office BP. However, night-time ambulatory BP recordings may interfere with sleep quality because of the device cuff inflation and frequency of measurements. Hence, there is an unmet need for obtaining high quality BP values during sleep. In the last two decades, technological development of home BP devices enabled automated BP measurements during night-time...
November 3, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30362985/childhood-prediction-models-for-hypertension-later-in-life-a-systematic-review
#4
Marleen Hamoen, Marlou L A de Kroon, Marieke Welten, Hein Raat, Jos W R Twisk, Martijn W Heymans, Yvonne Vergouwe
BACKGROUND: Hypertension, even during childhood, increases the risk of developing atherosclerosis and cardiovascular disease. Therefore, starting prevention of hypertension early in the life course could be beneficial. Prediction models might be useful for identifying children at increased risk of developing hypertension, which may enable targeted primordial prevention of cardiovascular disease. OBJECTIVE: To provide an overview of childhood prediction models for future hypertension...
October 22, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30339551/proteomic-profiling-of-endothelium-dependent-vasodilation
#5
Lars Lind, Johan Sundström, Johan Ärnlöv, Erik Ingelsson
OBJECTIVE: As endothelial dysfunction is an early event in atherosclerosis formation, we investigated if proteins previously related to cardiovascular disease also were related to endothelial function using a novel targeted proteomics approach. METHODS: In the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study (n = 850-970, all aged 70 years), endothelium-dependent vasodilation (EDV) in the forearm was assessed by intra-arterial infusion of acetylcholine...
October 18, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30335670/melatonin-enhances-atherosclerotic-plaque-stability-by-inducing-prolyl-4-hydroxylase-%C3%AE-1-expression
#6
Hongxuan Li, Jingyuan Li, Xiuxin Jiang, Shangming Liu, Yan Liu, Weiqian Chen, Jianmin Yang, Cheng Zhang, Wencheng Zhang
OBJECTIVE: Melatonin, an endogenous neurohormone secreted predominately by the pineal gland, has a variety of physiological functions. However, its protective role in atherosclerosis is not clear. In this study, we sought to investigate the potential effects of melatonin in modulating atherosclerotic plaque stability in apolipoprotein E knockout (ApoE) mice. METHOD AND RESULTS: Smooth muscle cells were treated with melatonin, which significantly increased mRNA and protein levels of a key intracellular enzyme essential for collagen maturation and secretion, prolyl-4-hydroxylase α1 (P4Hα1)...
October 17, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30325341/sbp-above-180-mmhg-at-moderate-exercise-workload-increases-coronary-heart-disease-risk-in-healthy-men-during-28-year-follow-up
#7
Julian E Mariampillai, Erik E Prestgaard, Sverre E Kjeldsen, Knut Liestøl, Kristian Engeseth, Jan Erikssen, Johan Bodegard, Eivind Berge, Irene Grundvold, Per T Skretteberg
OBJECTIVE: We investigated the association between exercise SBP at a moderate workload and long-term risk of coronary heart disease (CHD) in men who were healthy when assessed by two bicycle exercise tests 7 years apart. METHODS: During 1972-1975, apparently healthy men (n = 1999) were initially enrolled following thorough medical examination and ECG-monitored bicycle exercise test. Participants (n = 1392) who were healthy also at a second exercise test 7 years later were included in the present study...
October 12, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30308598/hypertension-prevalence-and-risk-factors-among-residents-of-four-slum-communities-population-representative-findings-from-port-au-prince-haiti
#8
Olga Tymejczyk, Margaret L McNairy, Jacky S Petion, Vanessa R Rivera, Audrey Dorélien, Mireille Peck, Grace Seo, Kathleen F Walsh, Daniel W Fitzgerald, Robert N Peck, Ashish Joshi, Jean W Pape, Denis Nash
OBJECTIVES: The aim of this study was to estimate the prevalence of hypertension and its risk factors among adults in four slum communities in Port-au-Prince. METHODS: Cluster area random sampling was used to select adults for a health and demographic survey, including anthropometric measurements. Hypertension was defined as SBP at least 140 mmHg and/or DBP at least 90 mmHg, or current hypertension treatment, and was age-standardized to WHO world population...
October 10, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30308597/performance-of-simplified-tables-for-high-blood-pressure-screening-in-a-european-pediatric-population
#9
Stella Stabouli, Thomaitsa Nika, Konstantinos Kollios, Christina Antza, Ioannis Doundoulakis, Vasilios Kotsis
OBJECTIVE: We assessed the performance of the simplified American Academy Pediatrics (AAP) 2017 guideline table and a simplified table based on the Fourth Report blood pressure (BP) reference tables for high BP screening compared with the European Society Hypertension 2016 guideline diagnostic thresholds. METHODS: We obtained data from a cross-sectional, school-based screening study in north Greece during 2013-2016. BP was measured by mercury sphygmomanometer. The simple tables' performance for high BP was assessed by receiver operator characteristic curve analysis, area under the curve (AUC), sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV)...
October 10, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30308596/arterial-stiffness-in-normal-pregnancy-at-11-13-weeks-of-gestation-and-risk-of-late-onset-hypertensive-disorders-of-pregnancy
#10
Luca Marozio, Giulia Chiarle, Claudia Filippini, Stephanie Challancin, Annalisa Tancredi, Elsa Viora, Chiara Benedetto
OBJECTIVE: We evaluated the possible correlation between pulse wave analysis (PWA) parameters measured during the first trimester of pregnancy in normotensive, low-risk women, and the development of hypertensive disorders later in pregnancy. Our hypothesis was that a still asymptomatic increase in arterial stiffness may potentially precede the onset of overt hypertension in pregnancy and that PWA could detect it. METHODS: The study population (n = 1648) was recruited at the time of prenatal screening for chromosomal abnormalities (11-12 weeks of gestation)...
October 10, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30308595/transgenic-overexpression-of-glutathione-s-transferase-%C3%AE-type-1-reduces-hypertension-and-oxidative-stress-in-the-stroke-prone-spontaneously-hypertensive-rat
#11
Erin Olson, Michal Pravenec, Vladimir Landa, H H Caline Koh-Tan, Anna F Dominiczak, Martin W McBride, Delyth Graham
BACKGROUND: Combined congenic breeding and microarray gene expression profiling previously identified glutathione S-transferase μ-type 1 (Gstm1) as a positional and functional candidate gene for blood pressure (BP) regulation in the stroke-prone spontaneously hypertensive (SHRSP) rat. Renal Gstm1 expression in SHRSP rats is significantly reduced when compared with normotensive Wistar Kyoto (WKY) rats. As Gstm1 plays an important role in the secondary defence against oxidative stress, significantly lower expression levels may be functionally relevant in the development of hypertension...
October 10, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30308594/recurrent-vertigo-is-a-predictor-of-stroke-in-a-large-cohort-of-hypertensive-patients
#12
Pierre-Yves Courand, Michael Serraille, Adrien Grandjean, Caroline Tilikete, Hugues Milon, Brahim Harbaoui, Pierre Lantelme
OBJECTIVE: Dizziness is associated with hypertension but there are numerous other causes. The aims of the present study were to describe the characteristics and the clinical correlates of dizziness in a large cohort of hypertensive patients, and to test its prognostic value for all-cause, cardiovascular, and stroke mortality. METHODS: A total of 1716 individuals from the OLD-HTA Lyon's cohort of hypertensive patients recruited in the 1970s were categorized according to the absence or the presence of dizziness...
October 10, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30308593/interaction-between-low-density-lipoprotein-cholesterolaemia-serum-uric-level-and-incident-hypertension-data-from-the-brisighella-heart-study
#13
Arrigo F G Cicero, Federica Fogacci, Marina Giovannini, Elisa Grandi, Sergio D'Addato, Claudio Borghi
OBJECTIVE: Previous evidence suggest that high low-density lipoprotein cholesterol (LDL-C) and serum uric acid (SUA) levels are risk factors for endothelial dysfunction and vascular ageing. The aim of our study was to evaluate the short-term interaction between SUA, LDL-C and incident hypertension in a sample of overall healthy individuals. METHODS: In January 2018, we selected from the general database of the Brisighella Heart Study four groups of age and sex-matched nonhypertensive individuals with different levels of LDL-C and SUA level and examined during the 2008 population survey...
October 10, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30300252/combined-impact-of-risk-factors-on-the-subsequent-development-of-hypertension
#14
Yuli Huang, Zhihui Deng, Zhen Se, Yujia Bai, Chuanjie Yan, Qiong Zhan, Qingchun Zeng, Ping Ouyang, Meng Dai, Dingli Xu
OBJECTIVES: This study aimed to develop a cumulative score composed of seven risk factors: age, resting heart rate, overweight or obesity, dyslipidemia, hyperuricemia, impaired glucose regulation, and impaired estimated glomerular filtration rate (eGFR), to evaluate the risk of new-onset hypertension. METHODS: We retrospectively conducted a cohort study in 23 665 participants free from hypertension at baseline, who attended at least two annual health examinations between 2011 and 2016...
October 8, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30300251/effects-of-herbs-and-spices-on-blood-pressure-a-systematic-literature-review-of-randomised-controlled-trials
#15
Kate S Driscoll, Amanda Appathurai, Markandeya Jois, Jessica E Radcliffe
: Hypertension is a major risk factor for cardiovascular disease, affecting 1 billion people worldwide. Literature suggests some herbs and spices have cardiovascular benefits, such as decreasing blood pressure; yet evidence is inconsistent. This article reviewed randomized controlled trials investigating effects of herbs and spices on blood pressure in normotensive, pre-hypertensive and hypertensive participants. Ovid Medline, Embase, Biological abstracts, CINAHL and Cochrane Collaboration were systematically searched...
October 8, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30299422/impact-of-the-2017-blood-pressure-guidelines-by-the-american-academy-of-pediatrics-in-overweight-obese-youth
#16
Procolo Di Bonito, Giuliana Valerio, Lucia Pacifico, Claudio Chiesa, Cecilia Invitti, Anita Morandi, Maria Rosaria Licenziati, Melania Manco, Emanuele Miraglia Del Giudice, Marco Giorgio Baroni, Sandro Loche, Gianluca Tornese, Francesca Franco, Claudio Maffeis, Giovanni de Simone
OBJECTIVES: The aim of this study was to compare the impact of the European Society of Hypertension Guidelines 2016 (ESHG2016) and the American Academy of Pediatrics Guidelines 2017 (AAPG2017) on the screening of hypertension and classification of abnormal left ventricular geometry (ALVG) in overweight/obese youth. METHODS: This study included 6137 overweight/obese youth; 437 had echocardiographic assessment. Hypertension was defined using either ESHG2016 or AAPG2017...
October 6, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30234786/different-prognostic-associations-of-beta-blockers-and-diuretics-in-heart-failure-with-preserved-ejection-fraction-with-versus-without-high-blood-pressure
#17
Kenichi Matsushita, Kazumasa Harada, Tetsuro Miyazaki, Takamichi Miyamoto, Shun Kohsaka, Kiyoshi Iida, Shuzou Tanimoto, Makoto Takei, Toru Hosoda, Yoshiya Yamamoto, Yasuyuki Shiraishi, Hideaki Yoshino, Takeshi Yamamoto, Ken Nagao, Morimasa Takayama
OBJECTIVE: No agents have been proven to improve survival in heart failure with preserved ejection fraction (HFpEF), but the phenotypic diversity of HFpEF suggests it may be possible to identify specific HFpEF phenotypes that will benefit from certain treatments. This study compared the risk factors for and prognostic impacts of treatments on in-hospital mortality between HFpEF patients with (+) and without (-) high blood pressure (HBP). METHODS: Data on 2238 consecutive HFpEF patients were extracted from Tokyo CCU Network data registry and analysed...
September 17, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30234785/the-utility-of-long-term-blood-pressure-variability-for-cardiovascular-risk-prediction-in-primary-care
#18
Sarah L Stevens, Richard J McManus, Richard J Stevens
OBJECTIVES: Blood pressure (BP) is a long-established risk factor for cardiovascular disease (CVD). SBP is used in all widely used cardiovascular risk scores for clinical decision-making. Recently, within-person BP variability has been shown to be a major predictor of CVD. We investigated whether cardiovascular risk scores could be improved by incorporating BP variability with standard risk factors. METHODS: We used cohort data on patients aged 40-74 on 1 January 2005, from English general practices contributing to the Clinical Practice Research Datalink, a research database derived from electronic health records...
September 17, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30234784/determinants-of-pulse-wave-velocity-trajectories-from-youth-to-young-adulthood-the-georgia-stress-and-heart-study
#19
Xiaohua Liang, Shaoyong Su, Guang Hao, Harold Snieder, Frank Treiber, Gaston Kapuku, Xiaoling Wang
OBJECTIVE: Increased arterial stiffness measured by pulse wave velocity (PWV) has been shown to be an important parameter of cardiovascular risk. Longitudinal development of PWV from youth to early adulthood and its possible sociodemographic, anthropometric, hemodynamic and behavioral moderators will be illustrated. METHODS: Individual growth curves of carotid-distal PWV across age were created for 559 African American and European American men and women with a maximum of five assessments over an average of 7-year follow-up (mean age at participants' first assessment, 22...
September 17, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/30234783/agreement-between-24-h-dietary-recalls-and-24-h-urine-collections-for-estimating-sodium-intake-in-china-japan-uk-usa-the-international-study-of-macro-and-micro-nutrients-and-blood-pressure
#20
Xiaoxiao Wen, Long Zhou, Jeremiah Stamler, Queenie Chan, Linda Van Horn, Martha L Daviglus, Alan R Dyer, Paul Elliott, Hirotsugu Ueshima, Katsuyuki Miura, Nagako Okuda, Yangfeng Wu, Liancheng Zhao
OBJECTIVE: The present study aims to compare 24-h dietary recalls with 24-h urine collections for the estimation of sodium intake at both population and individual levels in China, Japan, the United Kingdom (UK), and the United States of America (USA), using data from the International Study of Macro- and Micro-nutrients and Blood Pressure (INTERMAP). METHODS: Mean differences between 24-h dietary recalls and 24-h urine collections were calculated for their agreement in estimating sodium intake at the population level; relative and absolute differences as well as misclassification of salt intake groups (salt intake <6, 6-8...
September 17, 2018: Journal of Hypertension
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