Simona Sestito, Lucia Brodosi, Stefania Ferraro, Rosa Carella, Donatella De Giovanni, Dorina Mita, Michele Moretti, Maria Teresa Moricca, Daniela Concolino, Albina Tummolo
Background: Maternal phenylketonuria (mPKU) is a pathologic condition occurring in the fetus of a mother with PKU that is caused by prolonged elevated intrauterine blood phenylalanine (Phe) levels, which can lead to congenital abnormalities and mental retardation of newborns. Management of PKU during pregnancy can be challenging as protein substitutes may exacerbate nausea, vomiting, and gastrointestinal symptoms. Aim: To report the successful management of four PKU pregnant women. Methods: The patients were administered with prolonged-release amino acid supplementation and were recommended to follow a strict diet...
April 23, 2024: Nutrition and Health