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Ultraschall in der Medizin

Thomas Schramm, Helge Mommsen
Skeletal disorders of the fetus are quite common. The incidence is about 5:1000 pregnancies. The disorders affect the extremities or parts of them (dysmelia), the whole skeleton (skeletal dysplasia), the skull (craniosynostosis) and the spine (dysostosis, caudal regression). About half of these diseases are complex. In the majority of cases the complex disorders are caused by single gene mutations or numeric or structural chromosomal aberrations. We explain the classification and diagnostic criteria for prenatal expert and screening ultrasound based on frequent disorders...
September 6, 2018: Ultraschall in der Medizin
Xin-Bao Zhao, Ji-Yi Yao, Xin Chuan Zhou, Shao-Yun Hao, Wen Jie Mu, Lu-Jing Li, Wen-Jing Zhong, Zhi Hui
BACKGROUND:  Breast lesions classified as BI-RADS-US 3 are probably benign and observation was recommended, while a considerable number of BI-RADS-US 4 lesions were benign, resulting in excessive biopsies. We focus exclusively on BI-RADS-US 3 and 4 lesions and hypothesize that improved diagnostic performance can be achieved by integrating real-time elastography (strain ratio) into the BI-RADS-US classification system. METHOD:  From April 2010 to September 2015, 1071 lesions were included in the final analysis...
September 3, 2018: Ultraschall in der Medizin
Jörg Bojunga
Thyroid nodules are a common finding in the general population. Ultrasonography is the most sensitive imaging tool for diagnosing thyroid nodules. However, sonographic differentiation of hormonally active versus inactive nodules, and in particular benign versus malignant nodules, remains unreliable. In this context, thyroid scintigraphy has its clinical significance predominantly in diagnosing hormonal activity of thyroid nodules. However, most nodules are benign and a significant number of patients undergo surgery for diagnostic rather than for therapeutic reasons...
September 3, 2018: Ultraschall in der Medizin
Christian Fischer, Tabea Haug, Marc-Andre Weber, Hans-Ulrich Kauczor, Thomas Bruckner, Gerhard Schmidmaier
No abstract text is available yet for this article.
August 30, 2018: Ultraschall in der Medizin
Andre Farrokh, Linn Treu, Ralf Ohlinger, Carolin Flieger, Nicolai Maass, Fritz Kw Schäfer
PURPOSE:  The aim of the present study was to determine the accuracy of breast cancer measurement with 2 D shear wave elastography (2 D SWE), B-mode ultrasound, and mammography by comparing these methods with the actual histopathological tumor size. MATERIALS AND METHODS:  135 patients with proven malignant breast lesions at two centers were included in a prospective study. The maximum lesion diameter was measured by 2 D SWE, B-mode ultrasound, and mammography...
August 20, 2018: Ultraschall in der Medizin
Youn Joo Lee, Sung Hun Kim, Bong Joo Kang, Yun Ju Kim
PURPOSE:  To evaluate the time-intensity curve (TIC) parameters on contrast-enhanced ultrasound (CEUS) for early prediction of the response of breast cancer to neoadjuvant chemotherapy (NAC). MATERIALS AND METHODS:  This prospective study included 41 patients with breast cancer. CEUS was performed before and after the first cycle of NAC. TIC parameters were analyzed for different regions of interest (ROIs). ROI 1 targeted the hotspot area of greatest enhancement, ROI 2 delineated the area of hyperenhancement, ROI 3 included the entire tumor on grayscale ultrasound, and ROI 4 encircled the normal parenchyma...
August 13, 2018: Ultraschall in der Medizin
Christian Fischer, Tabea Haug, Marc-Andre Weber, Hans-Ulrich Kauczor, Thomas Bruckner, Gerhard Schmidmaier
PURPOSE:  To assess the value of CEUS in the evaluation of tibial fracture perfusion and its ability to differentiate between physiologic and abnormal fracture healing. MATERIALS AND METHODS:  From 2014 to 2017, 107 patients with tibial fractures or tibial non-unions underwent CEUS examination. CEUS was performed at the regular follow-up examination 26 weeks after osteosynthesis or before non-union surgery. Time-intensity curves (TICs) of the contrast enhancement in the fracture gap were generated, and volume parameters such as wash-in rate (WiR), peak enhancement (PE) and wash-in perfusion index (WiPI) were quantified...
August 6, 2018: Ultraschall in der Medizin
Peter Kozlowski, Tilo Burkhardt, Ulrich Gembruch, Markus Gonser, Christiane Kähler, Karl-Oliver Kagan, Constantin von Kaisenberg, Philipp Klaritsch, Eberhard Merz, Horst Steiner, Sevgi Tercanli, Klaus Vetter, Thomas Schramm
First-trimester screening between 11 + 0 and 13 + 6 weeks with qualified prenatal counseling, detailed ultrasound, biochemical markers and maternal factors has become the basis for decisions about further examinations. It detects numerous structural and genetic anomalies. The inclusion of uterine artery Doppler and PlGF screens for preeclampsia and fetal growth restriction. Low-dose aspirin significantly reduces the prevalence of severe preterm eclampsia. Cut-off values define groups of high, intermediate and low probability...
July 12, 2018: Ultraschall in der Medizin
Christoph Klinger, Bettina Riecken, Christoph Frank Dietrich, Klaus Dirks, Karel Caca, Eckhart Fröhlich
PURPOSE:  To evaluate the use of ultrasound (US) in the diagnostic work-up of adult intussusception (AI). METHODS:  This multicenter study includes 26 consecutive patients diagnosed with AI between January 2010 and November 2017. A retrospective chart analysis was conducted with a focus on abdominal US findings and diagnostic accuracy of different imaging modalities (ultrasound, computed tomography (CT), magnetic resonance imaging). If available, surgical and pathological findings served as the gold standard (76...
July 5, 2018: Ultraschall in der Medizin
Teresa Antonia Kiener, Christoph Wohlmuth, Christa Schimke, Martha Georgina Brandtner, Dagmar Wertaschnigg
PURPOSE:  Parents confronted with the finding of antenatal hydronephrosis (ANH) are particularly interested in whether their baby will need postnatal surgery. The objective of this study was to predict ANH requiring surgery on the basis of the fetal anteroposterior renal pelvic diameter (APRPD) and the Society for Fetal Urology (SFU) grading system. MATERIALS AND METHODS:  The medical records of 179 patients with the finding of ANH were reviewed retrospectively...
July 5, 2018: Ultraschall in der Medizin
Jürgen Hoffmann, Mario Marx, Andreas Hengstmann, Harald Seeger, Ernst Oberlechner, Gisela Helms, Carmen Röhm, Claudia Ott, Diethelm Wallwiener, Annette Stäbler, Benjamin Wiesinger, Andreas D Hartkopf, Sara Y Brucker, Markus Hahn
PURPOSE:  Breast-conserving therapy is associated with a risk of tumor-involved margins. For intraoperative orientation, non- palpable or indistinctly palpable lesions are wire-marked prior to surgery. Ultrasound-guided surgery has the potential to reduce the number of tumor-involved margins. In the MAC 001 trial we evaluated ultrasound-guided breast-conserving surgery compared to wire-guided surgery with regard to free tumor margins, duration of surgery and resection volume. MATERIALS AND METHODS:  In this randomized, prospective, single-center controlled trial, patients with ductal invasive breast cancer were recruited for either ultrasound-guided or wire localization surgery...
July 5, 2018: Ultraschall in der Medizin
Andrea Dall'Asta, Noortje Hm van Oostrum, Sheikh Nigel Basheer, Gowrishankar Paramasivam, Tullio Ghi, Letizia Galli, Irene Al Groenenberg, Amanda Tangi, Patrizia Accorsi, Monica Echevarria, Maria Angeles Rodríguez Perez, Gerard Albaiges Baiget, Federico Prefumo, Tiziana Frusca, Attie Tji Go, Christoph C Lees
OBJECTIVES:  We sought to assess the causes and outcomes of severe VM diagnosed de novo after 24 weeks of gestation where a mid-trimester anomaly scan was described as normal. METHODS:  Multicenter retrospective study of five European fetal medicine centers. The inclusion criteria were normal anatomy at the mid-trimester scan, uni/bilateral finding of posterior ventricle measuring ≥ 15 mm after 24 weeks with neonatal and postnatal pediatric and/or neurological assessment data...
July 5, 2018: Ultraschall in der Medizin
Christoph F Dietrich
No abstract text is available yet for this article.
July 4, 2018: Ultraschall in der Medizin
Kaid Darwiche, Filiz Özkan, Celina Wolters, Stephan Eisenmann
No abstract text is available yet for this article.
July 4, 2018: Ultraschall in der Medizin
Karina Krajden Haratz, Yaakov Melcer, Zvi Leibovitz, Hagit Feit, Tally Lerman-Sagie, Dorit Lev, Shimon Ginath, Liat Gindes, Antonio Fernandes Moron, Gustavo Malinger
No abstract text is available yet for this article.
July 4, 2018: Ultraschall in der Medizin
Andrea De Gottardi, Annalisa Berzigotti, Elisabetta Buscarini, Angeles García Criado
Vascular liver diseases include a heterogeneous group of disorders affecting the micro- and the macro-circulation of the liver. Thrombosis and obstruction of the inflow (portal vein) and/or outflow venous system (Budd-Chiari syndrome), spontaneous porto-systemic shunts, diseases affecting the sinusoids, and hepatic vascular malformations are the most important vascular liver diseases. Thrombosis of the portal venous system and of the hepatic venous system occur most commonly and are potentially life-threatening conditions, while congenital and acquired pro-thrombotic diseases are major causal factors, together with local factors triggering thrombotic events...
August 2018: Ultraschall in der Medizin
Lea Marie Pehrson, Carsten Lauridsen, Michael Bachmann Nielsen
No abstract text is available yet for this article.
August 2018: Ultraschall in der Medizin
Carla Serra, Valentina Grasso, Fabio Conti, Cristina Felicani, Elena Mazzotta, Marco Lenzi, Gabriella Verucchi, Antonietta D'errico, Pietro Andreone
PURPOSE:  To assess the performance of two-dimensional shear wave elastography (2D-SWE) on the GE LOGIQ E9 ultrasound system in a cohort of healthy subjects and to investigate its accuracy in the staging of liver fibrosis in patients with chronic liver disease (CLD) using liver biopsy as a reference standard. MATERIALS AND METHODS:  From October 2014 to June 2016, 54 healthy subjects and 174 patients with CLD were consecutively enrolled. Liver fibrosis stage was assessed by the METAVIR scoring system...
August 2018: Ultraschall in der Medizin
Giampiero Francica, Maria Franca Meloni, Ilario de Sio, Fulvia Terracciano, Eugenio Caturelli, Laura Riccardi, Paola Roselli, Maddalena Diana Iadevaia, Mariano Scaglione, Giovanni Lenna, Jason Chiang, Maurizio Pompili
PURPOSE:  To retrospectively characterize the prevalence and impact of contrast-enhanced ultrasound (CEUS) as a guidance technique for the biopsy of liver target lesions (LTLs) at six interventional ultrasound centers. MATERIALS AND METHODS:  The six participating centers retrospectively selected all patients in whom biopsy needles were positioned in LTLs during CEUS. The prevalence of CEUS-guided biopsies at each center between 2005 and 2016, contrast agent consumption, procedure indications, diagnostic yield and complications were assessed...
August 2018: Ultraschall in der Medizin
Regina Tschannen, Rita Gobet, Josef Wisser
OBJECTIVE:  To assess prenatal prognostic criteria for fetuses with megacystis in order to counsel parents. METHODS:  In a retrospective observational study at a single tertiary referral center, we assessed the clinical course of 53 fetuses with megacystis cared for at the Department of Obstetrics of the University Hospital Zurich between 1995 and 2008 and followed them up for 2 to 12 years. We determined fetal karyotype, amniotic fluid volume and fetal urinary biochemistry as prenatal prognostic factors...
August 2018: Ultraschall in der Medizin
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