journal
MENU ▼
Read by QxMD icon Read
search

Nutrition Research

journal
https://www.readbyqxmd.com/read/27993193/intake-of-bilberries-vaccinium-myrtillus-l-reduced-risk-factors-for-cardiovascular-disease-by-inducing-favorable-changes-in-lipoprotein-profiles
#1
Marta Habanova, Jorge A Saraiva, Miroslav Haban, Marianna Schwarzova, Peter Chlebo, Lenka Predna, Jan Gažo, Joanna Wyka
Cardiovascular diseases (CVDs) are the leading causes of death, and lifestyle modification, including dietary changes, is recommended to improve this condition. In this study, regular consumption of bilberries was hypothesized to have beneficial effects on CVD risk reduction, by changes in human health indicators such as decreasing low-density lipoprotein cholesterol (LDL-C) and triglycerides (TGs) and increasing high-density lipoprotein cholesterol (HDL-C). The research involved women (n=25) and men (n=11) who consumed 150 g of frozen stored bilberries 3 times a week for 6 weeks...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27993192/polyphenol-enriched-vaccinium-uliginosum-l-fractions-reduce-retinal-damage-induced-by-blue-light-in-a2e-laden-arpe19-cell-cultures-and-mice
#2
Bom-Lee Lee, Jung-Hwan Kang, Hye-Mi Kim, Se-Hee Jeong, Dae-Sik Jang, Young-Pyo Jang, Se-Young Choung
Polyphenols exert beneficial effects on vision. We hypothesized that polyphenol components of Vaccinium uliginosum L. (V.U.) extract protect retinal pigment epithelial (RPE) cells against blue light-induced damage. Our aim was to test extracts containing polyphenol components to ascertain effects to reduce damage against blue light in RPEs. We measured the activity in fractions eluted from water, ethanol, and HP20 resin (FH), and found that the FH fraction had the highest beneficial activity. We isolated the individual active compounds from the FH fraction using chromatographic techniques, and found that FH contained flavonoids, anthocyanins, phenyl propanoids, and iridoids...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27932080/vitamin-c-impacts-anxiety-like-behavior-and-stress-induced-anorexia-relative-to-social-environment-in-smp30-gnl-knockout-mice
#3
Miwako Koizumi, Yoshitaka Kondo, Ayumi Isaka, Akihito Ishigami, Emiko Suzuki
The role of endogenous vitamin C (VC) in emotion and psychiatric measures has long been uncertain. We aimed to investigate how an individual's VC status impacts his or her mental health. Our hypothesis is that body VC levels modulate anxiety, anorexia, and depressive phenotypes under the influence of psychosocial rearing environments and sex. The VC status of senescence marker protein-30/gluconolactonase knockout mice, which lack the ability to synthesize VC, were continuously shifted from adequate (VC+) to depleted (VC-) by providing a water with or without VC...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27923524/the-therapeutic-potential-of-metabolic-hormones-in-the-treatment-of-age-related-cognitive-decline-and-alzheimer-s-disease
#4
REVIEW
John Grizzanti, Hyoung-Gon Lee, Antoni Camins, Merce Pallas, Gemma Casadesus
Aging leads to a number of physiological alterations, specifically changes in circulating hormone levels, increases in fat deposition, decreases in metabolism, changes in inflammatory responses, and reductions in growth factors. These progressive changes in physiology and metabolism are exacerbated by modern culture and Western diet and give rise to diseases such as obesity, metabolic syndrome, and type 2 (non-insulin-dependent) diabetes (T2D). These age and lifestyle-related metabolic diseases are often accompanied by insulin and leptin resistance, as well as aberrant amylin production and signaling...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27919453/dietary-tartary-buckwheat-intake-attenuates-insulin-resistance-and-improves-lipid-profiles-in-patients-with-type-2-diabetes-a-randomized-controlled-trial
#5
Ju Qiu, Yanping Liu, Yanfen Yue, Yuchang Qin, Zaigui Li
Tartary buckwheat (TB) is rich in protein, dietary fiber, and flavonoids and has been reported to affect type 2 diabetes mellitus (T2DM) in animal experiments, but limited information on the benefit of TB as a whole food in T2DM patients is available. Thus, we tested the hypothesis that a daily replacement of a portion of the staple food with TB will improve risk factors of T2DM, including fasting glucose, insulin resistance, and lipid profile. In a parallel, randomized, open-label, controlled trial, 165 T2DM patients were randomly assigned to a control diet group (DC group; systematic diet plans and intensive nutritional education) or a TB intervention group (TB group; daily replacement of a portion of staple food with TB food)...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27890482/dietary-nitrate-does-not-affect-physical-activity-or-outcomes-in-healthy-older-adults-in-a-randomized-cross-over-trial
#6
Mario Siervo, Clio Oggioni, Djordje G Jakovljevic, Michael Trenell, John C Mathers, David Houghton, Carlos Celis-Morales, Ammar W Ashor, Alan Ruddock, Mayur Ranchordas, Markos Klonizakis, Elizabeth A Williams
Although dietary nitrate (NO3(-)) ingestion appears to enhance exercise capacity and performance in young individuals, inconclusive findings have been reported in older people. Therefore, we conducted a double-blind, crossover randomized clinical trial using beetroot juice in older healthy participants, who were classified as normal weight and overweight. We tested whether consumption of beetroot juice (a rich source of NO3(-)) for 1 week would increase nitric oxide bioavailability via the nonenzymatic pathway and enhance (1) exercise capacity during an incremental exercise test, (2) physical capability, and (3) free-living physical activity...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27890481/growth-disparity-of-motherless-children-might-be-attributed-to-a-deficient-intake-of-high-quality-nutrients
#7
Hui Wang, Xu Tian, Shaowei Wu, Zhibin Hu
We hypothesized that single-parent children (SPC) are retarded in growth compared with both-parent children (BPC), and that motherless children (MC) are affected differently from fatherless children. Moreover, the growth disparity between SPC and BPC might be attributed to a deficient nutrient intake. Data from 2967 children between the ages of 2 and 18 years were extracted from 4 recent waves (2004, 2006, 2009, and 2011) of the China Health and Nutrition Survey to compare the growth status of SPC and BPC and to investigate the association between growth indicators and nutrition status...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27889107/combination-of-the-anthocyanidins-malvidin-and-peonidin-attenuates-lipopolysaccharide-mediated-inflammatory-gene-expression-in-primary-human-adipocytes
#8
Jessica D Mackert, Michael K McIntosh
We recently demonstrated that California table grapes and a methanol-extractable, polyphenol-rich fraction decreased adiposity, insulin resistance, or markers of inflammation in high-fat fed mice. Malvidin and peonidin glycosides were the 2 most abundant anthocyanins in the polyphenol-rich fraction. We hypothesized that a blood borne combination of anthocyanidins malvidin and peonidin derived from intestinal β-glycosidase metabolism of these 2 anthocyanins are responsible, in part, for the beneficial health effects observed in vivo...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27884414/low-muscle-mass-is-associated-with-metabolic-syndrome-in-korean-adolescents-the-korea-national-health-and-nutrition-examination-survey-2009-2011
#9
Jeong-Hyeon Kim, Yong Soon Park
Little is known about the relationship between low muscle mass (LMM) and metabolic risk factors in adolescents. We hypothesized that LMM in adolescents is associated with metabolic syndrome (MetS) and its components in Korean adolescents. This cross-sectional study included 1420 participants (749 males and 671 females), aged 12 to 19 years, who participated in the 2009-2011 Korea National Health and Nutrition Examination Surveys. Appendicular skeletal muscle mass was divided by body weight, and any value below the lower quintile of the study population, according to each age and sex category, was considered to represent LMM...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27884413/peroxisome-proliferator-activated-receptor-%C3%AE-down-regulation-mediates-the-inhibitory-effect-of-d-%C3%AE-tocotrienol-on-the-differentiation-of-murine-3t3-f442a-preadipocytes
#10
Sheida Torabi, Hoda Yeganehjoo, Chwan-Li Shen, Huanbiao Mo
Tocotrienols accelerate the degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase that catalyzes the biosynthesis of mevalonate; the latter is essential for preadipocyte differentiation. Tocotrienols also down-regulate peroxisome proliferator-activated receptor γ (PPARγ), a key regulator of adipocyte differentiation. We hypothesized that mevalonate deprivation and PPARγ down-regulation mediate d-δ-tocotrienol-induced inhibition of adipocyte differentiation. The objectives of this study were to determine the effect of d-δ-tocotrienol on 3T3-F442A preadipocyte differentiation and the involvement of PPARγ and mevalonate...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27866830/a-high-fat-diet-differentially-regulates-glutathione-phenotypes-in-the-obesity-prone-mouse-strains-dba-2j-c57bl-6j-and-akr-j
#11
Katie M Norris, Whitney Okie, Woo Kyun Kim, Roshan Adhikari, Sarah Yoo, Stephanie King, Robert Pazdro
The ubiquitous tripeptide glutathione (GSH) is a critical component of the endogenous antioxidant defense system. Tissue GSH concentrations and redox status (GSH/GSSG) are genetically controlled, but it is unclear whether interactions between genetic background and diet affect GSH homeostasis. The current study tested the hypothesis that a high-fat diet regulates GSH homeostasis in a manner dependent on genetic background. At 4 months of age, female mice representing 3 obesity-prone inbred strains-C57BL/6J (B6), DBA/2J (D2), and AKR/J (AKR)-were randomly assigned to consume a control (10% energy from fat) or high-fat (62% energy from fat) diet for 10 weeks (n=5/diet per strain)...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27866828/high-fat-western-diet-induced-obesity-contributes-to-increased-tumor-growth-in-mouse-models-of-human-colon-cancer
#12
Ann Marie O'Neill, Christine M Burrington, Erin A Gillaspie, Darin T Lynch, Melissa J Horsman, Michael W Greene
Strong epidemiologic evidence links colon cancer to obesity. The increasing worldwide incidence of colon cancer has been linked to the spread of the Western lifestyle, and in particular consumption of a high-fat Western diet. In this study, our objectives were to establish mouse models to examine the effects of high-fat Western diet-induced obesity on the growth of human colon cancer tumor xenografts, and to examine potential mechanisms driving obesity-linked human colon cancer tumor growth. We hypothesize that mice rendered insulin resistant due to consumption of a high-fat Western diet will show increased and accelerated tumor growth...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27866827/nucleoprotein-supplementation-enhances-the-recovery-of-rat-soleus-mass-with-reloading-after-hindlimb-unloading-induced-atrophy-via-myonuclei-accretion-and-increased-protein-synthesis
#13
Ryosuke Nakanishi, Yusuke Hirayama, Minoru Tanaka, Noriaki Maeshige, Hiroyo Kondo, Akihiko Ishihara, Roland R Roy, Hidemi Fujino
Hindlimb unloading results in muscle atrophy and a period of reloading has been shown to partially recover the lost muscle mass. Two of the mechanisms involved in this recovery of muscle mass are the activation of protein synthesis pathways and an increase in myonuclei number. The additional myonuclei are provided by satellite cells that are activated by the mechanical stress associated with the reloading of the muscles and eventually incorporated into the muscle fibers. Amino acid supplementation with exercise also can increase skeletal muscle mass through enhancement of protein synthesis and nucleotide supplements can promote cell cycle activity...
December 2016: Nutrition Research
https://www.readbyqxmd.com/read/27955723/nutrition-ethical-issues-and-challenges
#14
REVIEW
Robert B Rucker, Michael R Rucker
For nutrition and its associated disciplines, ethical considerations related to research are often complicated by factors that range from the use of experimental research designs that are overly holistic to inextricable links between nutrition research and marketing. As a consequence, there is the need for constant vigilance to assess and deal with apparent conflicts of interest. Also, there are few scientific disciplines that are defined by cultural, religious, or political codifications as is nutrition. Accordingly, examples of historical, cultural, and political events are described that have influenced ethical approaches related to nutrition research...
November 2016: Nutrition Research
https://www.readbyqxmd.com/read/27866829/lutein-and-zeaxanthin-supplied-by-red-orange-foods-and-fruits-are-more-closely-associated-with-macular-pigment-optical-density-than-those-from-green-vegetables-in-spanish-subjects
#15
Rocío Estévez-Santiago, Begoña Olmedilla-Alonso, Beatriz Beltrán-de-Miguel, Carmen Cuadrado-Vives
Lutein and zeaxanthin (L+Z) accumulate in the retina. Although vegetables are major contributors to their intake, a stronger association between fruits and macular pigment optical density (MPOD) has been reported. We hypothesized that L+Z intake from fruits would have a stronger association with L+Z status markers (MPOD, serum concentrations) than intake from vegetables or eggs, and that those associations would also differ according to plant foods color. One hundred eight subjects (57 men; age groups, 20-35 and 45-65 years) were enrolled in a cross-sectional study...
November 2016: Nutrition Research
https://www.readbyqxmd.com/read/27865621/menaquinone-4-vitamin-k2-up-regulates-expression-of-human-intestinal-alkaline-phosphatase-in-caco-2-cells
#16
Seiko Noda, Asako Yamada, Rieko Tanabe, Kanae Nakaoka, Takayuki Hosoi, Masae Goseki-Sone
Alkaline phosphatase (ALP) hydrolyzes several monophosphate esters into inorganic acid and alcohol. In humans, 4 kinds of ALP isozymes have been identified: tissue-nonspecific ALP, intestinal ALP, placental ALP, and germ cell ALP. Intestinal ALP is expressed at a high concentration in the brush border membrane of intestinal epithelial cells and is known to be affected by several kinds of nutrients, such as lipids, but the physiological function of intestinal ALP has remained elusive. Vitamin K is an essential cofactor for the posttranslational carboxylation of glutamate residues into γ-carboxy glutamate...
November 2016: Nutrition Research
https://www.readbyqxmd.com/read/27865620/consumption-of-chokeberry-aronia-mitschurinii-products-modestly-lowered-blood-pressure-and-reduced-low-grade-inflammation-in-patients-with-mildly-elevated-blood-pressure
#17
Britt-Marie Loo, Iris Erlund, Raika Koli, Pauli Puukka, Jarkko Hellström, Kristiina Wähälä, Pirjo Mattila, Antti Jula
Previous studies suggest that consumption of chokeberries may improve cardiovascular disease risk factor profiles. We hypothesized that chokeberries (Aronia mitschurinii) have beneficial effects on blood pressure, low-grade inflammation, serum lipids, serum glucose, and platelet aggregation in patients with untreated mild hypertension. A total of 38 participants were enrolled into a 16-week single blinded crossover trial. The participants were randomized to use cold-pressed 100% chokeberry juice (300 mL/d) and oven-dried chokeberry powder (3 g/d), or matched placebo products in random order for 8 weeks each with no washout period...
November 2016: Nutrition Research
https://www.readbyqxmd.com/read/27865619/inhibition-on-the-growth-of-human-mda-mb-231-breast-cancer-cells-in-vitro-and-tumor-growth-in-a-mouse-xenograft-model-by-se-containing-polysaccharides-from-pyracantha-fortuneana
#18
Chengfu Yuan, Changdong Wang, Junjie Wang, Vikas Kumar, Firoz Anwar, Fangxiang Xiao, Gohar Mushtaq, Yufei Liu, Mohammad Amjad Kamal, Ding Yuan
Breast cancer is the second cause of cancer-related death among Women. Current therapies for breast cancer have adverse side-effects. Selenium (Se)-containing polysaccharides have multiple health benefits to humans. Pyracantha fortuneana (P. fortuneana) contains rich Se polysaccharides. We hypothesized that Se-containing polysaccharides from P. fortuneana possess anticancer activity on breast cancer via inhibiting growth and inducing apoptosis. This study aimed to assess the anticancer effect of Se-containing polysaccharides from P...
November 2016: Nutrition Research
https://www.readbyqxmd.com/read/27865618/actinidia-arguta-supplementation-protects-aorta-and-liver-in-rats-with-induced-hypercholesterolemia
#19
Maria Leontowicz, Hanna Leontowicz, Iwona Jesion, Wojciech Bielecki, Katarzyna Najman, Piotr Latocha, Yong-Seo Park, Shela Gorinstein
There are no published results focusing on the study of hardy kiwifruit as a supplementation to the atherogenic diet. We hypothesized that hardy kiwifruit (Actinidia arguta (A. arguta)) from Poland possess better pro-healthy action than two Asian varieties (Hayward and Bidan). We tested this hypothesis by measuring the metabolic reactions of rats loaded with 1% cholesterol and supplemented with 5% of hardy kiwifruit (A. arguta), Hayward, or Bidan in their diets. The experiment was performed on 71 male Wistar rats...
November 2016: Nutrition Research
https://www.readbyqxmd.com/read/27865617/panaxatriol-derived-from-ginseng-augments-resistance-exercised-induced-protein-synthesis-via-mtorc1-signaling-in-rat-skeletal-muscle
#20
Yusuke Takamura, Yuhei Makanae, Satoru Ato, Naomi Yoshii, Kohei Kido, Mitsuru Nomura, Akira Uchiyama, Naruhiro Shiozawa, Satoshi Fujita
Resistance exercise activates muscle protein synthesis via the mammalian target of rapamycin complex 1 (mTORC1) pathway and subsequent muscle hypertrophy. Upstream components of the mTORC1 pathway are widely known to be involved in Akt and extracellular signal-regulated kinase 1/2 (ERK1/2) signaling. Previous studies have shown that ginseng stimulated Akt and ERK1/2 signaling. Therefore, we hypothesized that panaxatriol (PT) derived from ginseng triggers mTORC1 signaling and muscle protein synthesis by activating both the Akt and ERK1/2 signaling pathways, and that PT additively stimulates muscle protein synthesis when combined with resistance exercise...
November 2016: Nutrition Research
journal
journal
28580
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"