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Nutrition Research

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https://www.readbyqxmd.com/read/28506517/fish-oil-supplementation-benefits-the-murine-host-during-the-acute-phase-of-a-parasitic-infection-from-trypanosoma-cruzi
#1
Maria I Lovo-Martins, Aparecida D Malvezi, Rosiane V da Silva, Nágela G Zanluqui, Vera L H Tatakihara, Niels O S Câmara, Ana Paula L de Oliveira, Jean P S Peron, Marli C Martins-Pinge, Kevin L Fritsche, Phileno Pinge-Filho
Long-chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA) are known to modulate a variety of immune cell functions. On occasion, this has led to diminished host resistance to certain viral and bacterial infections. Little is known about the impact of n-3 PUFA on host resistance to parasitic infection, however, based on results from a small study conducted more than two decades ago, we hypothesized that providing mice LC n-3 PUFA will diminish host resistance to Trypanosoma cruzi, the parasitic pathogen responsible for Chagas disease...
April 25, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28506518/the-addition-of-peanuts-to-habitual-diets-is-associated-with-lower-consumption-of-savory-non-core-snacks-by-men-and-sweet-non-core-snacks-by-women
#2
Jayne A Barbour, Emilija Stojanovski, Lisa J Moran, Peter R C Howe, Alison M Coates
Snacking is associated with intakes of non-core foods which may predispose to obesity. Peanuts have potential satiety benefits and may assist with weight management; we hypothesized that peanut consumption would reduce intake of non-core snack foods due to compensation. We investigated the effects of adding peanuts to a habitual diet on snacking habits and energy intake. Sixty-one healthy participants (65±7years, body mass index 31±4kg/m(2)) consumed their habitual diet with or without peanuts (56g/d for 32 women, 84g/d for 29 men) for 12weeks each in a randomized crossover design...
April 20, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28477944/a-high-protein-diet-during-hospitalization-is-associated-with-an-accelerated-decrease-in-soluble-urokinase-plasminogen-activator-receptor-levels-in-acutely-ill-elderly-medical-patients-with-sirs
#3
Juliette Tavenier, Thomas H Haupt, Aino L Andersen, Sussi F Buhl, Anne Langkilde, Jens R Andersen, Jens-Erik B Jensen, Mette M Pedersen, Janne Petersen, Ove Andersen
Acute illness and hospitalization in elderly individuals are often accompanied by the systemic inflammatory response syndrome (SIRS) and malnutrition, both associated with wasting and mortality. Nutritional support and resistance training were shown to increase muscle anabolism and reduce inflammation in healthy elderly. We hypothesized that nutritional support and resistance training would accelerate the resolution of inflammation in hospitalized elderly patients with SIRS. Acutely admitted patients aged >65 years with SIRS were randomized to an intervention consisting of a high-protein diet (1...
April 20, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28479226/bifidobacterium-adolescentis-im38-ameliorates-high-fat-diet-induced-colitis-in-mice-by-inhibiting-nf-%C3%AE%C2%BAb-activation-and-lipopolysaccharide-production-by-gut-microbiota
#4
Su-Min Lim, Dong-Hyun Kim
Gut microbiota play essential roles in the regulation of human metabolism via symbiotic interactions with the host. Prolonged consumption of high-fat diet (HFD) elevates the Firmicutes to Bacteroidetes ratio and lipopolysaccharide (LPS) production by gut microbiota, thereby increasing the probability of developing metabolic and immune disorders such as obesity and colitis. The use of probiotics with anti-inflammatory properties has been suggested to counteract this effect. Here, we tested whether Bifidobacterium adolescentis IM38, which inhibited nuclear factor-kappa B (NF-κB) activation in Caco-2 cells and peritoneal macrophages and inhibited Escherichia coli LPS production, exerted an anticolitic effect in mice with HFD-induced obesity...
April 19, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28465000/long-term-soft-drink-and-aspartame-intake-induces-hepatic-damage-via-dysregulation-of-adipocytokines-and-alteration-of-the-lipid-profile-and-antioxidant-status
#5
Mohamed A Lebda, Hossam G Tohamy, Yasser S El-Sayed
Dietary intake of fructose corn syrup in sweetened beverages is associated with the development of metabolic syndrome and obesity. We hypothesized that inflammatory cytokines play a role in lipid storage and induction of liver injury. Therefore, this study intended to explore the expression of adipocytokines and its link to hepatic damage. Rats were assigned to drink water, cola soft drink (free access) and aspartame (240 mg/kg body weight/day orally) for 2 months. The lipid profiles, liver antioxidants and pathology, and mRNA expression of adipogenic cytokines were evaluated...
April 19, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28464999/light-coffee-consumption-is-protective-against-sarcopenia-but-frequent-coffee-consumption-is-associated-with-obesity-in-korean-adults
#6
Jeong-Hyeon Kim, Yong Soon Park
Few studies have examined the effects of coffee on body composition in the general population. In this cross-sectional study, we hypothesized that coffee consumption is protective against obesity and sarcopenia in Korean adults. The study included 6906 subjects aged ≥40 years who participated in the Korean National Health and Nutrition Examination Survey in 2009-2010. Body composition was measured using dual-energy x-ray absorptiometry, and obesity was determined according to the body mass index (BMI) and waist circumference (WC)...
April 19, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28477945/secretion-metabolites-of-probiotic-yeast-pichia-kudriavzevii-as-12-induces-apoptosis-pathways-in-human-colorectal-cancer-cell-lines
#7
Amir Saber, Beitollah Alipour, Zeinab Faghfoori, Ali Mousavi Jam, Ahmad Yari Khosroushahi
There is a common agreement on the important role of the gastrointestinal microbiota in the etiology of cancer. Benign probiotic yeast strains are able to ameliorate intestinal microbiota and regulate the host metabolism, physiology, and immune system through anti-inflammatory, antiproliferative, and anticancer effects. We hypothesized that Pichia kudriavzevii AS-12 secretion metabolites possess anticancer activity on human colorectal cancer cells (HT-29, Caco-2) via inhibiting growth and inducing apoptosis...
April 18, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28291551/marine-n-3-polyunsaturated-fatty-acids-affect-the-blood-pressure-control-in-patients-with-newly-diagnosed-hypertension-a-1-year-follow-up-study
#8
Carina N Bagge, Charlotte Strandhave, Charlotte M Skov, My Svensson, Erik B Schmidt, Jeppe H Christensen
Marine long-chained n-3 polyunsaturated fatty acids (PUFA) are recognized for their cardio-protective effects, including potential lowering of blood pressure. We hypothesized that higher habitual fish intake and n-3 PUFA plasma levels were associated with lower blood pressure and being less likely to receive antihypertensive medication after one-year follow-up. In this prospective study of 115 patients, we assessed 24 h ambulatory and central blood pressure, plasma phospholipid fatty acid composition using gas chromatography and participants completed a food frequency questionnaire, including fish-eating habits...
February 28, 2017: Nutrition Research
https://www.readbyqxmd.com/read/28473063/weight-loss-achieved-using-an-energy-restriction-diet-with-normal-or-higher-dietary-protein-decreased-the-number-of-cd14-cd16-proinflammatory-monocytes-and-plasma-lipids-and-lipoproteins-in-middle-aged-overweight-and-obese-adults
#9
Jung Eun Kim, Ge Lin, Jing Zhou, Julie A Mund, Jamie Case, Wayne W Campbell
Monocytes are involved in immune responses, and specific monocyte subpopulations (MS) that express intermediate to high levels of CD16 are associated with obesity and cardiovascular events. Consuming high protein (HP) when dieting improves body composition and cardiometabolic health outcomes, but whether HP affects MS during weight loss remains unknown. We assessed the effect of HP on energy restriction (ER)-induced changes in MS in overweight and obese adults. The relations between MS and plasma lipids and lipoproteins were also examined...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28473062/coffee-consumption-prevents-fibrosis-in-a-rat-model-that-mimics-secondary-biliary-cirrhosis-in-humans
#10
Jonathan Arauz, Natanael Zarco, Erika Hernández-Aquino, Marina Galicia-Moreno, Liliana Favari, José Segovia, Pablo Muriel
Investigations demonstrated that oxidative stress plays an important role in injury promotion in cholestatic liver disease. We hypothesized that coffee attenuates cholestasis-induced hepatic necrosis and fibrosis via its antioxidant, anti-inflammatory, and antifibrotic properties. The major aim of this study was to evaluate the hepatoprotective properties of coffee and caffeine in a model of chronic bile duct ligation (BDL) in male Wistar rats. Liver injury was induced by 28-day BDL, and conventional coffee, decaffeinated coffee, or caffeine was administered daily...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28473061/long-term-interdisciplinary-therapy-decreases-symptoms-of-binge-eating-disorder-and-prevalence-of-metabolic-syndrome-in-adults-with-obesity
#11
Paula Bresciani Leite, Ana Raimunda Dâmaso, Vanessa Schoenardie Poli, Ricardo Badan Sanches, Stephan Garcia Andrade Silva, João Pedro Novo Fidalgo, Maythe Amaral Nascimento, Camila Aparecida Machado de Oliveira, Danielle Arisa Caranti
Obesity-associated comorbidities greatly impact the quality and expectancy of life. Binge eating disorder (BED) is the most prevalent eating disorder and it is an important risk factor for obesity and metabolic syndrome (MetS). For these reasons, we aimed to assess the effect of an interdisciplinary therapy on the symptoms of BED and the prevalence of MetS in obese adults. It was hypothesized that the interdisciplinary therapy would decrease symptoms of BED and markers of MetS. Twenty-four volunteers (BMI 34...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28473060/zinc-supplementation-reduces-rankl-opg-ratio-and-prevents-bone-architecture-alterations-in-ovariectomized-and-type-1-diabetic-rats
#12
Elaine C S Ferreira, Raul H Bortolin, Francisco P Freire-Neto, Karla S C Souza, João F Bezerra, Marcela A G Ururahy, Ana M O Ramos, Silvia T Himelfarb, Bento J Abreu, Thiago V N Didone, Lucia F C Pedrosa, Aldo C Medeiros, Sonia Q Doi, José Brandão-Neto, Rosário D C Hirata, Luciana A Rezende, Maria G Almeida, Mario H Hirata, Adriana A Rezende
Type 1 diabetes mellitus (T1DM) and estrogen deficiency are associated with several alterations in bone turnover. Zinc (Zn) is required for growth, development, and overall health. Zinc has been used in complementary therapy against bone loss in several diseases. We hypothesized that Zn supplementation represents a potential therapy against severe bone loss induced by the combined effect of estrogen deficiency and T1DM. We evaluated the protective effect of Zn against bone alterations in a chronic model of these disorders...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28473059/nicotinamide-protects-hepatocytes-against-palmitate-induced-lipotoxicity-via-sirt1-dependent-autophagy-induction
#13
Chen Shen, Xiaobing Dou, Yue Ma, Wang Ma, Songtao Li, Zhenyuan Song
Lipotoxicity induced by saturated fatty acids (SFAs) plays a pathological role in the development of non-alcoholic fatty liver disease (NAFLD); however, the exact mechanism remains to be clearly elucidated. Palmitate is the most abundant SFA in the circulation and major lipotoxic inducer. Accumulating evidence supports that autophagy induction is protective against palmitate-induced cell death in a variety of cell types, including hepatocytes. Nicotinamide is the amide form of nicotinic acid (vitamin B3, Niacin) and a dietary supplementation as a source of vitamin B3...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28473058/increased-cytokine-production-by-monocytes-from-human-subjects-who-consumed-grape-powder-was-not-mediated-by-differences-in-dietary-intake-patterns
#14
Susan J Zunino, Nancy L Keim, Darshan S Kelley, Ellen L Bonnel, Elaine C Souza, Janet M Peerson
Recently, in a randomized, double-blind crossover study, we reported that consumption of grape powder by obese human subjects increased the production of the proinflammatory cytokines interleukin (IL)-1β and IL-6 by peripheral blood monocytes after ex vivo stimulation with bacterial lipopolysaccharide compared with the placebo treatment. We hypothesized that dietary grape powder increased the production of these cytokines by stimulated monocytes. To test this hypothesis, we used 24-hour dietary recall data to determine if differences in dietary patterns played a role in increased cytokine production...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28473057/quality-of-systematic-reviews-of-the-foods-with-function-claims-registered-at-the-consumer-affairs-agency-web-site-in-japan-a-prospective-systematic-review
#15
REVIEW
Hiroharu Kamioka, Kiichiro Tsutani, Hideki Origasa, Takahiro Yoshizaki, Jun Kitayuguchi, Mikiko Shimada, Wentao Tang, Hiromi Takano-Ohmuro
The objective of this review was to assess the quality of systematic reviews (SRs) based on the Foods with Function Claims (FFC) registered at the Consumer Affairs Agency (CAA) Web site in Japan by AMSTAR checklist. Study design was a prospective SR of SRs based on the FFC registered at the CAA Web site in Japan. We searched the database from 1 April 2015 (starting date) through 27 October 2015 on the CAA Web site. A full quality appraisal of identified articles was made using the combined tool based on the AMSTAR checklist developed to assess the methodological quality of SRs...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28473056/protein-and-exercise-in-the-prevention-of-sarcopenia-and-aging
#16
REVIEW
Manal A Naseeb, Stella L Volpe
Aging is associated with a progressive decline in skeletal muscle mass and strength. The decline, known as sarcopenia, could lead to physical disability, poor quality of life, and death. In addition, the older population usually experiences age-related muscle changes that affect muscle mass, muscular strength, and functional abilities. The purpose of this review is to describe the role of protein and exercise in slowing the progression of sarcopenia. It will also discuss whether age-related changes can be attenuated by dietary protein and exercise in the older population...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28438412/an-acute-intake-of-theobromine-does-not-change-postprandial-lipid-metabolism-whereas-a-high-fat-meal-lowers-chylomicron-particle-number
#17
Lotte Smolders, Ronald P Mensink, Jogchum Plat
Postprandial responses predict cardiovascular disease risk. However, only a few studies have compared acute postprandial effects of a low-fat, high-carbohydrate (LF) meal with a high-fat, low-carbohydrate (HF) meal. Furthermore, theobromine has favorably affected fasting lipids, but postprandial effects are unknown. Because both fat and theobromine have been reported to increase fasting apolipoprotein A-I (apoA-I) concentrations, the main hypothesis of this randomized, double-blind crossover study was that acute consumption of an HF meal and a theobromine meal increased postprandial apoA-I concentrations, when compared with an LF meal...
April 2017: Nutrition Research
https://www.readbyqxmd.com/read/28385290/post-prandial-systemic-8-isoprostane-increases-after-consumption-of-moderate-and-high-fat-meals-in-insufficiently-active-males
#18
S P Kurti, S R Emerson, S K Rosenkranz, C S Teeman, E M Emerson, B J Cull, J R Smith, C A Harms
A single high-fat meal (HFM) leads to an increase in triglycerides and oxidative stress. Oxidative stress can be assessed via 8-isoprostane generation, which is associated with the development of asthma and cardiovascular disease. No previous research has investigated whether airway and systemic 8-isoprostane increases postprandially in nonasthmatic participants according to the energy and fat content of a meal. Our purpose was to assess airway and systemic 8-isoprostane after a HFM and a true-to-life moderate-fat meal (MFM)...
March 2017: Nutrition Research
https://www.readbyqxmd.com/read/28385289/use-of-a-novel-docosahexaenoic-acid-formulation-vs-control-in-a-neonatal-porcine-model-of-short-bowel-syndrome-leads-to-greater-intestinal-absorption-and-higher-systemic-levels-of-dha
#19
Camilia R Martin, Barbara Stoll, Joanne Cluette-Brown, Adesola C Akinkuotu, Oluyinka O Olutoye, Kathleen M Gura, Pratibha Singh, Munir M Zaman, Michael C Perillo, Mark Puder, Steven D Freedman, Doug Burrin
Infants with short bowel syndrome (SBS) are at high risk for malabsorption, malnutrition, and failure to thrive. The objective of this study was to evaluate in a porcine model of SBS, the systemic absorption of a novel enteral Docosahexaenoic acid (DHA) formulation that forms micelles independent of bile salts (DHA-ALT®). We hypothesized that enteral delivery of DHA-ALT® would result in higher blood levels of DHA compared to a control DHA preparation due to improved intestinal absorption. SBS was induced in term piglets through a 75% mid-jejunoileal resection and the piglets randomized to either DHA-ALT® or control DHA formulation (N=5 per group) for 4 postoperative days...
March 2017: Nutrition Research
https://www.readbyqxmd.com/read/28385288/increased-naive-cd4-and-b-lymphocyte-subsets-are-associated-with-body-mass-loss-and-drive-relative-lymphocytosis-in-anorexia-nervosa-patients
#20
Ana Elegido, Montserrat Graell, Patricia Andrés, Alina Gheorghe, Ascensión Marcos, Esther Nova
Anorexia nervosa (AN) is an atypical form of malnutrition with peculiar changes in the immune system. We hypothesized that different lymphocyte subsets are differentially affected by malnutrition in AN, and thus, our aim was to investigate the influence of body mass loss on the variability of lymphocyte subsets in AN patients. A group of 66 adolescent female patients, aged 12-17 years, referred for their first episode of either AN or feeding or eating disorders not elsewhere classified were studied upon admission (46 AN-restricting subtype, 11 AN-binge/purging subtype, and 9 feeding or eating disorders not elsewhere classified)...
March 2017: Nutrition Research
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