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Nutrition Research

Moon-Jeong Chang, Yongsoon Park
Created in 1967, the Korean Nutrition Society (KNS) has been a vital contributor to the development of the health and nutrition of South Korea. With members from many different fields focusing on nutrition and health sciences, the impact of the KNS has not only been felt in South Korea, but also worldwide. The KNS has helped to establish and maintain dietary recommendations in addition to providing ways to make nutrition information readily available to members, as well as the public. The KNS has also established professional journals to advance scientific discoveries in nutrition and health...
August 17, 2018: Nutrition Research
Bohye Park, Joo Weon Lim, Hyeyoung Kim
Helicobacter pylori (H pylori) colonizes the human stomach and increases the risk of gastric diseases including gastric cancer. H pylori increases reactive oxygen species (ROS), which activate Janus-activator kinase 1 (Jak1)/signal transducers and activators of transcription 3 (Stat3) in gastric epithelial cells. ROS mediate hyperproliferation, a hallmark of carcinogenesis, by activating Wnt/β-catenin signaling in various cells. Lycopene is a potent antioxidant exhibiting anticancer effects. We hypothesized that lycopene may inhibit H pylori-induced hyperproliferation by suppressing ROS-mediated activation of Jak1/Stat3 and Wnt/β-catenin signaling, and β-catenin target gene expression in gastric epithelial cells...
July 21, 2018: Nutrition Research
Marian L Neuhouser
The prevalence of chronic diseases in the United States and around the world is very high and not sustainable by most health care systems. While the etiology is complex, many chronic diseases are preventable through life long practices of adhering to healthy dietary patterns, engaging in physical activity and maintaining acceptable weight. Healthy dietary patterns were defined in the 2015 Dietary Guidelines Advisory Committee Scientific Report as diets that are high in fruits, vegetables, whole grains, low and non-fat dairy and lean protein...
July 10, 2018: Nutrition Research
Xiuhua Shen, Wenjing Tang, Zhiping Yu, Wei Cai
A dietitian has qualifications in nutrition and dietetics and applies the science of food and nutrition to improve the health of individuals, groups, and communities. The Registered Dietitian (RD) credential has gained recognition over the years for its expertise. The accreditation systems were developed and have been used to ensure quality of this profession. Accreditation systems set standards for academic and professional training in nutrition and dietetics and reflect current research-based information...
July 10, 2018: Nutrition Research
Maen D Abou Ziki, Arya Mani
Metabolic syndrome is a cluster of inherited metabolic traits, which centers around obesity and insulin resistance and is a major contributor to the growing prevalence of cardiovascular disease. The factors that underlie the association of metabolic traits in this syndrome are poorly understood due to disease heterogeneity and complexity. Genetic studies of kindreds with severe manifestation of metabolic syndrome have led to the identification of casual rare mutations in the LDL receptor-related protein 6, which serves as a co-receptor with frizzled protein receptors for Wnt signaling ligands...
July 4, 2018: Nutrition Research
Anna Czajka, Ewa M Kania, Licia Genovese, Andrea Corbo, Giovanni Merone, Cecilia Luci, Sara Sibilla
Aging is a multifactorial and natural process that causes physiological changes in organs, tissues and cells over time. In the skin and cartilage, aging leads to a decrease in the synthesis and changes in the arrangement of proteoglycans and collagen, in addition to the loss of glycosaminoglycans, which are responsible for the integrity and health of these tissues. We hypothesized that daily oral supplementation with a liquid nutraceutical containing hydrolyzed fish collagen, vitamins, antioxidants and other active ingredients could improve skin texture and elasticity, and in addition have a protective effect on joint health...
September 2018: Nutrition Research
Asdrubal Aguilera-Mendez, María G Hernández-Equihua, Alfonso C Rueda-Rocha, Clotilde Guajardo-López, Renato Nieto-Aguilar, Deyanira Serrato-Ochoa, León F Ruíz Herrera, José A Guzmán-Nateras
Several reports have demonstrated that pharmacological concentrations of biotin reduce hyperglycemia, hypertriglyceridemia, and hypertension. We hypothesized that biotin could exert a protective effect on some illness-associated metabolic syndrome. To test this hypothesis, male Wistar rats were fed a diet containing 30% fructose in drinking water and classified into four groups: C, the control group; B, the group receiving biotin (intraperitoneal injection, 2 mg/kg); F, the group receiving fructose (30% w/v); and FB, the group receiving fructose-biotin...
September 2018: Nutrition Research
Eunyoung Ha, Ji-Hyun Bae
Herein, we hypothesized that ZIP11 variants would be important risk factors for chronic gastritis and that there would be an interaction effect of the relationship between their variants and spicy food intake on the development of chronic gastritis. Participants in this cross-sectional study (n = 3882 + 252) were recruited from a cohort of the Korean Genome and Epidemiology Study in 2001. Age, sex, education, smoking and drinking status, exercise, stress, and income level of all participants were determined by a questionnaire...
September 2018: Nutrition Research
Rui Lin, Xuan He, Huafeng Chen, Qin He, Ziting Yao, Yuanfan Li, Hui Yang, Steve Simpson
Oil tea has traditionally been used in minority populations in China for treating various ailments in traditional Chinese medicine. Individually, green tea and ginger, which are the main ingredients of oil tea, have demonstrated antidiabetic effects; however, whether oil tea exerts antidiabetic effects remains unknown. In addition, aberrant gut microbiota structure is associated with diabetic status, and research indicates that there may be beneficial effects of tea on gut microbiota. Therefore, we hypothesized that oil tea exerts antidiabetic effects and induces alteration in gut microbiota...
September 2018: Nutrition Research
Nerylee A Watson, Kathryn A Dyer, Jonathan D Buckley, Grant D Brinkworth, Alison M Coates, Gaynor Parfitt, Peter R C Howe, Manny Noakes, Karen J Murphy
Food cravings are common in type 2 diabetes (T2D). Higher-protein diets are effective in improving satiety but their effect on cravings is unclear. It was hypothesized that a high protein (HP) diet would provide greater reductions in cravings than an isocaloric higher-carbohydrate diet (HC). In a randomized controlled trial, 61 adults (54% males) with T2D (means ± SD: BMI 34.3 ± 5.1 kg/m2 ; aged 55 ± 8 years) consumed either a HP diet (mean across study: 29% protein, 34% carbohydrate, 31% fat) or an isocaloric HC diet (21%:48%:24%) for 12-weeks each of weight loss (WL) and weight maintenance (WM)...
September 2018: Nutrition Research
Soheil Varasteh, Saskia Braber, Aletta D Kraneveld, Johan Garssen, Johanna Fink-Gremmels
Heat stress (HS) induced by exposure to high ambient temperatures or prolonged excessive physical activities is known to primarily induce deleterious effects on the intestinal integrity by disrupting junctional complexes. Considering the association of l-arginine (l-Arg) with the improvement of gut function, the hypothesis of this study was to assess whether l-Arg supplementation can prevent the intestinal barrier disruption under HS conditions and to understand whether the l-Arg-induced effects are associated with maintaining nitric oxide (NO) as the major product of l-Arg metabolism...
September 2018: Nutrition Research
Yoriko Sato, Yusuke Sato, Kodwo Amuzuah Obeng, Fumiaki Yoshizawa
Branched-chain amino acids promote both protein and mRNA synthesis through mechanistic target of rapamycin (mTOR) signaling. A previous report demonstrated that chronic branched-chain amino acid supplementation increased mitochondrial biogenesis in the skeletal muscle of middle-aged mice through activation of mTOR signaling. In this study, we hypothesized that the acute oral administration of L-leucine alone has the ability to alter the gene expression related to fiber type and metabolism in skeletal muscle of young rats through the activation of mTOR signaling...
September 2018: Nutrition Research
Josefina Aguayo-Armendáriz, Maricela Montalvo-Corral, Karla A González-Martínez, María I Grijalva-Haro, Martha N Ballesteros-Vásquez, Graciela Caire-Juvera, Silvia Y Moya-Camarena
The relationship of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor γ (PPARγ) gene with obesity and its modulation by dietary fat has been proposed, but the few studies addressing this issue have yielded controversial results. In a Mexican population characterized by high-fat consumption, we hypothesized that the Pro12Ala PPARγ genotype is related to obesity and this relationship is modulated by intake of saturated fatty acids (SFAs) and trans-fatty acids (TFAs). We recruited 69 adults for this cross-sectional study...
September 2018: Nutrition Research
Lara M Nasreddine, Amira N Kassis, Jennifer J Ayoub, Farah A Naja, Nahla C Hwalla
The Eastern Mediterranean Region (EMR) is undergoing social and economic changes that may impact the nutritional status of children living in its countries. The objective of this review is to evaluate the nutritional status and dietary intakes of children (0-12 years) in selected EMR countries, namely, Jordan, Lebanon, Kingdom of Saudi Arabia (KSA), and the United Arab Emirates. MedLine, PubMed, Scopus, and Google Scholar were searched for relevant articles published between 1990 and 2016; international organizations and governmental websites were also searched...
September 2018: Nutrition Research
Hui Xu, Yu Ding, Xueling Xin, Weijing Wang, Dongfeng Zhang
Dietary fiber may reduce the bioavailability of steroid hormones and favorably regulate insulin-like growth factor 1, and therefore may be associated with ovarian cancer risk. Current evidence on the association between dietary fiber intake and risk of ovarian cancer is inconsistent. Therefore, we conducted a meta-analysis to explore the association. We hypothesized that dietary fiber intake might be associated with a reduced risk of ovarian cancer. PubMed, Web of Science, Embase, China National Knowledge Infrastructure, and Wanfang databases were searched for relevant articles up to September 2017...
September 2018: Nutrition Research
Flávia G Cândido, Fernanda C E de Oliveira, Mário Flávio C Lima, Carina A Pinto, Letícia L da Silva, Hércia S D Martino, Marcelo H Dos Santos, Rita de Cássia G Alfenas
We investigated if pumpkin and flaxseeds could improve postprandial glycemic, food intake, and appetitive responses. Herein, we hypothesize based on the literature that pumpkin seed has potential to lower postprandial glycemic effects. Therefore, we conducted a randomized, single-blind, placebo-controlled, crossover design study involving normoglycemic adults (food intake: n = 25; glycemia: n = 15). Three high-carbohydrate mixed meals presenting no seed (control [C]) or 65 g of the tested seeds (pumpkin seed [P] or flaxseed [F]) were consumed in 3 nonconsecutive days...
August 2018: Nutrition Research
Masashi Kuwahata, Yukiko Kobayashi, Yasuaki Wada, Wataru Aoi, Yasuhiro Kido
The oxidized/reduced state of plasma albumin in rats is influenced by the quantity of dietary protein. However, the effects of the protein quality on the oxidized/reduced state of plasma albumin are not clear. We hypothesized that the quality of dietary protein might modulate the oxidized/reduced state of plasma albumin. The aim of the present study was to examine whether the amino acid composition of dietary protein modulates the oxidized/reduced state of plasma albumin in rats. Male Sprague-Dawley rats were fed low-protein diets containing 5% casein (CA), 5% egg white (EW), or 6% wheat gluten (WG) for 2 weeks...
August 2018: Nutrition Research
Md Nazmul Haque, Mohammad Maqueshudul Haque Bhuiyan, Il Soo Moon
The naturally occurring phytosterol stigmasterol (ST) ameliorates scopolamine-induced memory impairment and promotes neuritogenesis and synaptogenesis. Therefore, in this study, we investigated the hypothesis that ST promotes spinogenesis and the formation of glutamatergic synapses and thus improves memory in cultured rat hippocampal neurons. Immunoblots showed that ST activated extracellular signal-regulated kinase 1/2 (Erk1/2) and cAMP response element binding protein (Creb), and upregulated actin-related protein 2 (Arp2) and cell division cycle 42 (Cdc42), central components in actin organization and spine head development...
August 2018: Nutrition Research
Agata Chmurzynska, Agnieszka Seremak-Mrozikiewicz, Anna M Malinowska, Agata Różycka, Anna Radziejewska, Artur Szwengiel, Grażyna Kurzawińska, Magdalena Barlik, Paweł P Jagodziński, Krzysztof Drews
Maternal metabolism during gestation may depend on nutrient intake but also on polymorphism of genes encoding enzymes involved in metabolism of different nutrients. Data on choline or carnitine metabolism in pregnant women are scarce. We hypothesized that (1) choline intake in Polish pregnant women is inadequate and (2) choline and carnitine metabolism would differ by genotype and nutritional status of pregnant women. One hundred three healthy Polish women aged 18 to 44 years in the third trimester of pregnancy were enrolled in the study...
August 2018: Nutrition Research
Jarinyaporn Naowaboot, Supaporn Wannasiri, Patchareewan Pannangpetch
Vernonia cinerea (V cinerea) is a plant distributed in grassy areas in Southeast Asia and has several pharmacological effects, including antidiabetic activity. However, the information available regarding the effect of V cinerea on insulin resistance in high-fat diet (HFD)-induced obese mice is not yet determined. We hypothesized that V cinerea water extract (VC) improves insulin sensitivity in HFD-induced obese mice by modulating both phosphatidylinositol-3-kinase (PI3K) and adenosine monophosphate-activated protein kinase (AMPK) pathways in liver, skeletal muscle, and adipose tissue...
August 2018: Nutrition Research
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