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Neurourology and Urodynamics

Jemin Ahn, Tatiana M Saltos, Veronica J Tom, Shaoping Hou
AIMS: This study was designed to determine specific cell groups of the raphe nuclei (RN) that give rise to supraspinal serotonergic projections regulating the bladder reflex. METHODS: Anesthetized rats underwent surgery to open the abdomen and expose the bladder. A total of 6 µL transsynaptic neuronal tracer pseudorabies virus (PRV-152), encoding for green fluorescent protein (GFP), was injected into the bladder detrusor. After 72 or 96 h, animals were perfused and the brain was dissected for processing transverse and sagittal sections...
July 12, 2018: Neurourology and Urodynamics
Werner Schaefer
No abstract text is available yet for this article.
July 12, 2018: Neurourology and Urodynamics
Bernard T Haylen, Audris Wong, Stephen Kerr
INTRODUCTION: Limited data exist associating vaginal vault and introital defects before and after posterior repairs (PR). We hypothesize: (i) a positive association between the size of vaginal vault and introital defects preoperatively; and (ii) a positive association between the reduction of these defects postoperatively if vault fixation (sacrospinous colpopexy-SSC) is used with the PR. METHODS: In a cross-sectional study of 300 consecutive PRs, the following were measured pre- and immediately postoperatively: (i) from POP-Q: genital hiatus (GH-Level III); (ii) from PR-Q: perineal gap (PG-Level III), posterior vaginal vault descent (PVVD-Level I)...
July 4, 2018: Neurourology and Urodynamics
Maria Dolores Carrillo-Izquierdo, Mahmoud Slim, Javier Hidalgo-Tallon, Elena P Calandre
AIMS: To evaluate the prevalence, distress, and impact of pelvic floor dysfunction (PFD) symptomatology in women with fibromyalgia and control women. We also aimed to evaluate the impact of PFD symptomatology on several psychosocial measures such as mood, sleep, pain, and quality of life. METHODS: We conducted a cross-sectional study in women with fibromyalgia and control women from the general population. Using a structured survey, we collected sociodemographic and clinical data, assessed the prevalence of PFD and evaluated the distress (PFDI-20) and the impact (PFIQ-7) caused by its symptomatology...
July 4, 2018: Neurourology and Urodynamics
Bernard T Haylen, Joseph K S Lee, Vasukhi Sivagnanam, Angela Cross
It is possible that the controversy involving prostheses implanted into women with pelvic floor problems might result in the majority of, or even all such products being restricted, banned or withdrawn in certain jurisdictions. A clear distinction between "tapes" for urinary incontinence and "mesh" for prolapse has been made in the enquiries and subsequent rulings in Australia and New Zealand. Transvaginal "mesh" will be unavailable with the range of "tapes" much more restricted in those countries from January 2018...
July 4, 2018: Neurourology and Urodynamics
Andrew Gammie, Darryl Kitney, Marcus Drake, Paul Abrams, Chris Fry
AIMS: To test the significance of association between a validated index of detrusor contractility, vCE , the Watts Factor, and the Detrusor Contractility Parameter, t20-80 ; and to test whether t20-80 depends on outflow tract resistance as indicated by Bladder Outlet Obstruction Index (BOOI). METHODS: Thirty-seven pressure-flow traces from 20 male and 17 female patients were analyzed and forms of the Watts Factor, t20-80 and BOOI were compared with vCE . RESULTS: The Detrusor Contractility Parameter, t20-80 , is significantly associated with vCE for both women and men without a high degree of bladder outlet obstruction...
July 4, 2018: Neurourology and Urodynamics
Joanie Mercier, An Tang, Mélanie Morin, Samir Khalifé, Marie-Claude Lemieux, Barbara Reichetzer, Chantale Dumoulin
AIMS: Test-retest reliability assessment of the dorsal clitoral artery's blood flow at rest and after muscle activation has never been documented. If this outcome measure is to be used in conditions impeding vascularity, it requires a psychometric evaluation. The aim of this study was to assess the inter-session test-retest reliability of clitoral blood flow in healthy women using color Doppler ultrasonography at rest and after a pelvic floor muscle (PFM) contraction task. METHODS: Two assessment sessions were conducted using a clinical ultrasound system...
June 28, 2018: Neurourology and Urodynamics
Amandine Guinet-Lacoste, Audrey Charlanes, Camille Chesnel, Emilie Blouet, Eliane Tan, Frédérique Le Breton, Gérard Amarenco
AIM: Patients who have successfully acquired the intermittent self-catheterization (ISC) technique can be expected to use it on a long-term basis. The aim of the present study is to present a validated evaluation scale, referred to as the ICAS (Intermittent Catheterization Adherence Scale), which can be used to assess long-term patient adherence to prescribed ISC treatment. METHODS: The scale was validated in neurologic and non neurologic patients in an experienced French neurourology center, between September 2014 and February 2016...
June 28, 2018: Neurourology and Urodynamics
Michael B Chancellor, Sarah N Bartolone, Elise M DeVries, Ananias C Diokno, Mark Gibbons, Ronald Jankowski, Laura E Lamb, Ryan Pruchnic, Karl Thor, Roger Dmochowski
BACKGROUND AND AIMS: Stakeholders from around the world came together to address the unmet needs of underactive bladder (UAB) at the 3rd International Congress for Underactive Bladder. METHODS: The main recommendation from the regulatory working group is a need for a meeting of UAB stakeholders and regulatory agencies including the FDA to discuss guidance for regulatory trial design for devices, drugs, and/or biologics for UAB. RESULTS: The following issues to be discussed and agreed upon for UAB trials: 1) Appropriate inclusion and exclusion criteria...
June 28, 2018: Neurourology and Urodynamics
Dirk De Ridder, Marcus Drake
No abstract text is available yet for this article.
June 28, 2018: Neurourology and Urodynamics
Werner Schaefer
No abstract text is available yet for this article.
June 28, 2018: Neurourology and Urodynamics
Kuan-Yin Lin, Ka-Chun Siu, Kuan-Han Lin
AIMS: The aim of this systematic review and meta-analysis was to determine the impact of lower urinary tract symptoms (LUTS) on work productivity in female workers. METHODS: A comprehensive literature search was conducted using eight electronic databases (MEDLINE, PEDro, CINAHL, Cochrane library, EMBASE, PubMed, Scopus, and PsycINFO) to identify articles published before July 2017 that studied the work productivity in female workers with LUTS. Two reviewers independently assessed the quality of studies using the Joanna Briggs Institute...
June 28, 2018: Neurourology and Urodynamics
Lin Chen, Yafei Yang, Jin Yang, Pinglin He, Bastian Amend, Arnulf Stenzl, Jianyun Hu, Yamei Zhang, Zili Wang
AIMS: Open surgery is the most commonly used methodological approach for generating a partial bladder outlet obstruction (pBOO) animal model. Surgical suturing closing a part of the urethral meatus induces comparable pathophysiological changes in bladder and renal functions, but the optimum degree of obstruction that closely mimics the clinical pathology of pBOO has not been elucidated. We investigated the optimum obstruction level by performing a comprehensive time-dependent analysis of the stability and reliability of this novel animal model...
June 28, 2018: Neurourology and Urodynamics
Xiaoshuai Gao, Tangqiang Wei, Banghua Liao, Jianzhong Ai, Liang Zhou, Lina Gong, Yuntian Chen, Qing He, Liang Cheng, Kunjie Wang
AIMS: To test a kind of stretch pattern which is the optimum stress parameter to promote human urothelial cells (HUCs) proliferation, and to investigate the roles of integrin subunits and their pathway in the HUCs proliferation induced by physiological stretch. METHODS: HUCs were seeded on silicone membrane, and subjected to four kinds of stretch (0,5%,10%,15% elongation) for 24 h, as controlled by a BioDynamic® bioreactor. Cell proliferation, viability and cycle distribution were examined using Cell Counting Kit-8 and flow cytometry, respectively...
June 28, 2018: Neurourology and Urodynamics
Rui Li, Quan Zhu, Mokhtar Nibouche, Andrew Gammie
AIMS: To review the descriptors and definitions of urine flow rate curve shape with a view to promoting greater clarity and to propose standard terms METHODS: A search was made in the PubMed and ICS standardization documents on urine flow rate curve shape. RESULTS: The flow shape descriptors and their definitions are summarized and presented. "Normal" was widely used for describing a bell-shaped flow curve, and "plateau" was mostly used where the ICS describe "constrictive" flow shape...
June 26, 2018: Neurourology and Urodynamics
Jian G Wen, Jens C Djurhuus, Peter F W M Rosier, Stuart B Bauer
AIMS: To introduce the standard procedure and results interpretation of pressure/flow study (PFS) in children. METHODS: The literature on PFS in children in PubMed for the last 20 years was reviewed. The updated knowledge on PFS in children in children regarding indication, preparation, technique, and interpretation were summarized. RESULTS: This educational module explains when and how to do a PFS and how to analyze the results. All requirements and instructions for the PFS in children described in this document follow ICS reports on Good Urodynamic Practice and urodynamic equipment performance as well as guidelines from the ICCS...
June 21, 2018: Neurourology and Urodynamics
Michael L Guralnick, Xavier Fritel, Tufan Tarcan, Montserrat Espuna-Pons, Peter F W M Rosier
INTRODUCTION: A cough stress test (CST) is recommended in the evaluation of the uncomplicated female patient with the complaint of stress urinary incontinence (SUI) to identify the sign of SUI, and is often used as an outcome measure following SUI treatment. However, there has been no standardization of the performance or reporting of CST. A working group of the International Continence Society (ICS) has developed an educational module, comprising a Powerpoint™ presentation and evidence base manuscript, to instruct on the performance, interpretation, and reporting of the CST in a standardized manner: the ICS-Uniform Cough Stress Test (ICS-UCST)...
June 21, 2018: Neurourology and Urodynamics
Lorna Booth, Dawn A Skelton, Suzanne Hagen, Joanne Booth
AIMS: To identify age and gender stratified normative values for the International Prostate Symptom Score (IPSS) for older community-living adults. METHODS: Secondary analysis of data from a large cohort study produced norms presented as means, standard deviations, medians, ranges, and percentile scores. Non-parametric analyses were conducted to investigate the effect that demographic variables, smoking status and comorbidity had on the severity of Lower Urinary Tract Symptoms (LUTS) as measured by the IPSS...
June 21, 2018: Neurourology and Urodynamics
Jure Tornic, Andrea M Sartori, Jerzy B Gajewski, Ashley Cox, Marc P Schneider, Nadim A Youssef, Livio Mordasini, Emmanuel Chartier-Kastler, Lucas M Bachmann, Thomas M Kessler
AIM: To systematically assess all available evidence on efficacy and safety of catheterization for treating neurogenic lower urinary tract dysfunction (NLUTD) in patients with multiple sclerosis (MS). METHODS: This systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies were identified by electronic search of Embase, Medline, Scopus, Cochrane register (last search March 3, 2018) and by screening of reference lists and reviews...
June 19, 2018: Neurourology and Urodynamics
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