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Andrea L C Schneider, Di Zhao, Pamela L Lutsey, Rebecca F Gottesman, A Richey Sharrett, Andreea M Rawlings, Alvaro Alonso, David Knopman, Thomas H Mosley, Elizabeth Selvin, Erin D Michos
BACKGROUND/AIMS: 25-hydroxyvitamin D (25[OH]D) concentrations have been associated with cognitive decline and incident dementia in elderly populations; however, these relationships are susceptible to reverse causation. Less is known about the association of midlife 25(OH)D with long-term cognitive decline. METHODS: This was a prospective cohort study of 13,044 participants (mean age 57 years at baseline) in the Atherosclerosis Risk in Communities Study. 25(OH)D was measured from serum collected at baseline (1990-1992) using liquid chromatography tandem high-sensitivity mass spectrometry...
August 9, 2018: Neuroepidemiology
Hebun Erdur, Stefanie Ernst, Michael Ahmadi, Andreas E Albers, Frank Marzinzik, Rajan Somasundaram, Heinrich J Audebert, Joachim E Weber
No abstract text is available yet for this article.
August 9, 2018: Neuroepidemiology
Wei Liu, Yanan Wu, Lingling Bai, Jingxian Ni, Jun Tu, Jie Liu, Quanjun Deng, Xianjia Ning, Jinghua Wang
BACKGROUND: At the global level, dementia is the leading cause of dependence and disability among the elderly. Although the preponderant prevalence in women has been identified, the sex differences in risk factors were unclear. We aimed to evaluate the sex differences in the prevalence of nonvascular cognitive impairment and the risk factors among the elderly in rural China screened with the Mini-Mental State Examination (MMSE). METHODS: Between 2014 and 2015, a population-based cross-section study was conducted to collect basic information among the elderly aged 60 years and over...
August 9, 2018: Neuroepidemiology
Lorene M Nelson, Barbara Topol, Wendy Kaye, David Williamson, D Kevin Horton, Paul Mehta, Todd Wagner
BACKGROUND: National administrative healthcare data may be used as a case-finding method for prevalence studies of chronic disease in the United States, but the completeness of ascertainment likely varies depending on the disease under study. METHODS: We used 3 case-finding sources (Medicare, Medicaid, and Veterans Administration data) to estimate the prevalence of amyotrophic lateral sclerosis (ALS) in the United States for 2002-2004, and applied the capture-recapture methodology to estimate the degree of under-ascertainment when relying solely on these sources for case identification...
August 9, 2018: Neuroepidemiology
Abhay Venkat, Cecilia Cappelen-Smith, Shabeel Askar, Peter R Thomas, Sonu Bhaskar, Amanda Tam, Alan J McDougall, Suzanne J Hodgkinson, Dennis J Cordato
BACKGROUND: Failure to recognise acute stroke may result in worse outcomes due to missed opportunity for acute stroke therapies. Our study examines factors associated with stroke misdiagnosis in patients admitted to a large comprehensive stroke centre. METHODS: Retrospective review comparing 156 consecutive stroke patients misdiagnosed in emergency department (ED) with 156 randomly selected stroke controls matched for age, gender, language spoken and stroke subtype for the period 2014-2016...
August 9, 2018: Neuroepidemiology
Valery L Feigin
No abstract text is available yet for this article.
August 8, 2018: Neuroepidemiology
Xuejun Yin, Lieyu Huang, Xiaowei Man, Yan Jiang, Xuan Zhao, Liying Zhao, Wei Cheng
BACKGROUND: Stroke has been the leading cause of death in China and contributed almost one-third to stroke deaths worldwide. The rising cost of stroke treatment is of great concern, but has not been thoroughly studied. This study aimed to analyze stroke in-hospital charges by subtypes, age, and sex and investigate potential factors associated with the cost of per stay. METHODS: The research was a retrospective observational study based on patients with a primary diagnosis of stroke from 31 hospitals in Beijing...
August 8, 2018: Neuroepidemiology
Rasha Khatib, Yurany A Arevalo, Mark A Berendsen, Shyam Prabhakaran, Mark D Huffman
AIMS: We performed a systematic review to evaluate stroke presentation, evaluation, management, and outcomes among studies conducted in low- and middle-income countries (LMIC). METHODS: We searched MEDLINE (Ovid), Embase (Elsevier), and the Global Health (EBSCOhost) databases between January 2005 and June 2017 for studies conducted in LMICs defined by the World Bank. We pooled prevalence estimates using an inverse-variance weighting method and stratified by the country income group...
July 19, 2018: Neuroepidemiology
Theodore C Larson, Wendy Kaye, Paul Mehta, D Kevin Horton
BACKGROUND: The International Classification of Disease, 10th Revision (ICD-10) did not include a code specific for Amyotrophic lateral sclerosis (ALS) until 2017. Instead, code G12.2 included both ALS and other motor neuron diseases (MND). Our objective was to determine US mortality rates for ALS exclusively by excluding other MND and progressive supranuclear palsy. METHODS: All mortality data coded as G12.2 under the pre-2017 rubric were obtained for 2011-2014...
July 10, 2018: Neuroepidemiology
Aida Adlimoghaddam, Banibrata Roy, Benedict C Albensi
Dementia is a growing public health concern in Canada. This epidemic is linked to huge human and economic costs. The number of Manitobans (65+) with dementia in 2045 (47,021), representing 2.58% of the Manitoban population, will be 2.3 times that of the year 2015 (20,235). The number of cases of dementia in Manitoba grew by 20.7% from 2015 to 2025, 68.16% from 2015 to 2035 and at an alarming rate of 125% from 2015 to 2045. Importantly, the total economic burden of dementia in Manitoba is close to one billion USD and is expected to grow more than 28 billion USD during the year 2038...
July 3, 2018: Neuroepidemiology
Manuela Chiavarini, Giulia Naldini, Roberto Fabiani
BACKGROUND: Many epidemiological studies have investigated the effect of maternal diet and prenatal multivitamin supplementation on pediatric cancer risk. Childhood brain and spinal cord tumors (CBSCT) have been attributed to different possible risk factors. METHODS: We conducted a systematic review and meta-analysis on maternal folate intake before and during pregnancy and the risk of CBSCT. We systematically reviewed publications obtained by searching the Insitute for Scientific Information Web of Knowledge and PubMed literature databases...
July 3, 2018: Neuroepidemiology
Joshua Z Willey, Yeseon P Moon, Mandip S Dhamoon, Erin R Kulick, Ahmet Bagci, Noam Alperin, Ying Kuen Cheung, Clinton B Wright, Ralph L Sacco, Mitchell S V Elkind
INTRODUCTION: White matter hyperintensity volume (WMHV) and subclinical brain infarcts (SBI) are associated with impaired mobility, but less is known about the association of WMHV in specific brain regions. We hypothesized that anterior WMHV would be associated with lower scores on the Short Physical Performance Battery (SPPB), a well-validated mobility scale. METHODS: The SPPB was measured a median of 5 years after enrollment into the Northern Manhattan MRI sub study...
June 28, 2018: Neuroepidemiology
Elan D Louis, James H Meyers, Ashley D Cristal, Pam Factor-Litvak
BACKGROUND: Caffeine can exacerbate tremor. Reducing caffeine intake or switching to decaffeinated beverages can lessen tremor. Unaffected relatives of essential tremor (ET) cases often have mild, subclinical tremor. One question is whether the coffee and tea consumption pattern in these individuals differs from that of controls (Co). METHODS: We ascertained the patterns of coffee and tea intake using a structured questionnaire, and compared the use in unaffected first-degree relatives of ET cases (FD-ET) to the use in age-matched Co...
June 28, 2018: Neuroepidemiology
Ólöf Elíasdóttir, Ólafur Kjartansson, Elias Olafsson
BACKGROUND: In this study, we examined multiple sclerosis (MS) point prevalence in the well-defined island population of Iceland. METHODS: This study included all registered residents of Iceland with MS on the prevalence day, December 31, 2007. All included patients met at least one of the following criteria: McDonald criteria; Poser criteria for clinically definite MS, laboratory-supported definite MS, clinically probable MS; or criteria for primary progressive MS...
June 25, 2018: Neuroepidemiology
Mònica Povedano, Marc Saez, Juan-Antonio Martínez-Matos, Maria Antònia Barceló
BACKGROUND: It is believed that an interaction between genetic and non-genetic factors may be involved in the development of amyotrophic lateral sclerosis (ALS). With the exception of exposure to agricultural chemicals like pesticides, evidence of an association between environmental risk factors and ALS is inconsistent. Our objective here was to investigate the association between long-term exposure to environmental factors and the occurrence of ALS in Catalonia, Spain, and to provide evidence that spatial clusters of ALS related to these environmental factors exist...
May 31, 2018: Neuroepidemiology
Valentina A Andreeva, Léopold K Fezeu, Serge Hercberg, Pilar Galan
BACKGROUND: The association between obesity and migraine has been established; however, it is unclear whether it varies by perceived stress within each gender. METHODS: This cross-sectional study used data from the ongoing NutriNet-Santé e-cohort with enrollees from the general population. Anthropometric and migraine data were provided via self-report questionnaires (2013-2016). Migraine was defined using established criteria. Perceived stress was assessed with Cohen's Perceived Stress Scale-10...
May 29, 2018: Neuroepidemiology
Kyla A McKay, Ruth Ann Marrie, John D Fisk, Scott B Patten, Helen Tremlett
BACKGROUND: Persons with multiple sclerosis (MS) use health resources with greater frequency than the general population. However, little is known regarding which patient characteristics might contribute. OBJECTIVE: The study aimed to evaluate characteristics associated with healthcare use in MS patients. METHODS: Consecutive MS clinic attendees were recruited (September-November 2010), with clinical, demographic, and patient-completed questionnaires collected at 3 visits over 2 years...
May 15, 2018: Neuroepidemiology
Moisés Rodríguez-Mañero, Estrella López-Pardo, Alberto Cordero, Omar Kreidieh, José Novo Platas, Luis Valdés, Adrian Cid-Menendez, Javier García-Seara, María Pereira-Vázquez, Jose-Luis Martínez-Sande, Alberto Ruano, Carlos Peña-Gil, Pilar Mazón, Jose María García-Acuña, José Ramón González-Juanatey
INTRODUCTION: Atrial fibrillation might increase the risk of dementia. We aim to test the hypothesis that dementia could reclassify the actual risk of stroke and death predicted by the CHA2DS2-VASc in patients with atrial fibrillation (AF). METHODS: A prospective study performed in a specific health care area. RESULTS: From our health care area (n = 348,985), throughout 2013, AF was codified in 7,990 (2.08%). Mean age was 76.83 ± 10.5, mean CHA2DS2-VASc = 3...
May 15, 2018: Neuroepidemiology
Eimear Smith, Patricia Fitzpatrick, John Murtagh, Frank Lyons, Seamus Morris, Keith Synnott
BACKGROUND: The International Spinal Cord Society and World Health Organisation recommend the collection of epidemiological data on traumatic spinal cord injury (TSCI). A 1-year prospective study is ongoing in Ireland. While the results of this study are awaited, it was concluded from a feasibility exercise that a complete retrospective dataset, 2010-2015, could be obtained and would be useful for service planning. METHODS: All patients with TSCI discharged from the national SCI acute and rehabilitation centres were included...
May 15, 2018: Neuroepidemiology
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No abstract text is available yet for this article.
February 22, 2018: Neuroepidemiology
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