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Neuroepidemiology

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https://www.readbyqxmd.com/read/28796991/epidemiology-of-intracranial-and-extracranial-large-artery-stenosis-in-a-population-based-study-of-stroke-in-the-middle-east
#1
Hamidreza Saber, Amin Amiri, Amanda G Thrift, Saverio Stranges, Reza Bavarsad Shahripour, Mohammad T Farzadfard, Naghmeh Mokhber, Réza Behrouz, Mahmoud Reza Azarpazhooh
BACKGROUND: Intracranial large-artery disease (LAD) is a predominant vascular lesion found in patients with stroke of Asian, African, and Hispanic origin, whereas extracranial LAD is more prevalent among Caucasians. These patterns are not well-established in the Middle East. We aimed to characterize the incidence, risk factors, and long-term outcome of LAD strokes in a Middle-Eastern population. METHODS: The Mashhad Stroke Incidence Study is a community-based study that prospectively ascertained all cases of stroke among the 450,229 inhabitants of Mashhad, Iran between 2006 and 2007...
August 11, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28793296/older-age-at-multiple-sclerosis-onset-is-an-independent-factor-of-poor-prognosis-a-population-based-cohort-study
#2
Francis Guillemin, Cédric Baumann, Jonathan Epstein, Philippe Kerschen, Teresa Garot, Guillaume Mathey, Marc Debouverie
BACKGROUND: Late-onset multiple sclerosis (LOMS) frequently features a primary progressive (PP) course, strongly predicting severe disability. In this population-based cohort, we estimated the prognostic role of age at multiple sclerosis (MS) onset, independent of PP course, on disability progression. METHODS: The association of age at disease onset (adult, <50 years [AOMS], vs. late, ≥50 years [LOMS]) and time to Expanded Disability Status Scale (EDSS) score 4 and 6 was estimated by Cox regression modelling...
August 10, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28793295/identifying-relapses-in-multiple-sclerosis-patients-through-administrative-data-a-validation-study-in-the-lazio-region-italy
#3
Paola Colais, Nera Agabiti, Marina Davoli, Fabio Buttari, Diego Centonze, Chiara De Fino, Marta Di Folco, Graziella Filippini, Ada Francia, Simonetta Galgani, Claudio Gasperini, Manuela Giuliani, Massimiliano Mirabella, Viviana Nociti, Carlo Pozzilli, AnnaMaria Bargagli
BACKGROUND: Relapse is frequently considered an outcome measure of disease activity in relapsing-remitting multiple sclerosis (MS). The objectives of this study were to identify relapse episodes in patients with MS in the Lazio region using health administrative databases and to evaluate the validity of the algorithm using patients enrolled at MS treatment centers. METHODS: MS cases were identified in the period between January 1, 2006 and December 31, 2009 using data from regional Health Information Systems (HIS)...
August 9, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28768287/the-association-of-poor-academic-performance-with-tic-disorders-a-longitudinal-mainstream-school-based-population-study
#4
Esther Cubo, Cristina Gonzalez, Vanesa Ausin, Vanesa Delgado, Sara Saez, Sara Calvo, Xose Garcia Soto, José Cordero, Katie Kompoliti, Elan D Louis, Raquel de la Fuente Anuncibay
BACKGROUND: Little is known about the academic performance of students with tic disorders (TD). Our aim was to investigate the association of TD and poor academic performance over time. METHODS: Longitudinal, observational study of mainstream schoolchildren comparing grade retention (GR) and learning disorders (LD) in students with vs. without TD between 2010 and 2014. Students with vs. without TD based on DSM-IV-TR criteria, or with vs. without GR and LD were compared in terms of comorbidities, school, and environmental characteristics...
July 29, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28743111/sleep-and-olfaction-among-older-adults
#5
V Eloesa McSorley, Jayant Pinto, L Philip Schumm, Kristen Wroblewski, David Kern, Martha McClintock, Diane S Lauderdale
BACKGROUND: Sleep and olfaction are both critical physiological processes that tend to worsen with age. Decline in olfaction can be an early indicator of neurodegenerative diseases, whereas poor sleep quality is associated with reduced physical and mental health. Given associations with aging-related health declines, we explored whether variations in sleep were associated with olfactory function among older adults. METHODS: We assessed the relationship between sleep characteristics and olfaction among 354 community-dwelling older adults...
July 26, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28728161/quality-of-life-and-caregivers-burden-of-parkinson-s-disease
#6
Kingston Rajiah, Mari Kannan Maharajan, Si Jen Yeen, Sara Lew
AIM: This study focused on the impact of the clinical features on the quality of life (QoL) of Parkinson's disease (PD) patients and of their caregivers. METHODS: This study included PD patients along with their caregivers and was undertaken at the Malaysian Parkinson's Disease Association from June 2016 to November 2016. Clinical features of PD patients were assessed using the Movement Disorder Society revised Unified Parkinson Disease Rating Scale; the Hoehn and Yahr stage and the Schwab and England Activities of Daily Living Scale were used to assess the severity and the ability of PD patients respectively...
July 21, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28728154/prevalence-of-primary-headache-disorders-in-kuwait
#7
Jasem Yousef Al-Hashel, Samar Farouk Ahmed, Raed Alroughani
BACKGROUND: Only an insignificant quantum of data exists on the prevalence of primary headaches among those living in Kuwait. We aimed to determine the prevalence of primary headaches among the Kuwaiti population. METHODS: This community-based study included Kuwaiti population aged 18-65 years. Using systematic random sampling, data was collected by the Headache-Attributed Restriction, Disability, Social Handicap and Impaired Participation questionnaire. Responses to the diagnostic questions were transformed into diagnoses algorithmically to confirm the diagnosis of primary headache...
July 21, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28683461/disease-modifying-therapies-and-adherence-in-multiple-sclerosis-comparing-patient-self-report-with-pharmacy-records
#8
Kyla A McKay, Charity Evans, John D Fisk, Scott B Patten, Kirsten Fiest, Ruth Ann Marrie, Helen Tremlett
BACKGROUND: Self-report and pharmacy records are often used to measure adherence rates to disease-modifying therapies (DMTs) in multiple sclerosis (MS), but little is known about how the sources compare. OBJECTIVE: Compare self-report and pharmacy records for assessing DMT use and adherence rates. METHODS: Demographic information, self-reported DMT use, and missed DMT doses in the previous 30 days were obtained from consecutive MS patients attending an MS clinic and linked to pharmacy records...
July 7, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28641305/incidence-of-autoimmune-myasthenia-gravis-in-a-health-maintenance-organization-in-buenos-aires-argentina
#9
Mariela Bettini, Marcelo Chaves, Edgardo Cristiano, Vanina Pagotto, Lucia Perez, Diego Giunta, Marcelo Rugiero
BACKGROUND: Different epidemiological studies, especially in Europe, have estimated the incidence density of myasthenia gravis (MG) to range between 1.7 and 21.3/1,000,000/person-year; however, data from regions such as Latin America are scarce. This study is aimed at estimating the incidence and prevalence of acquired MG in Buenos Aires, Argentina. METHODS: The study population comprised of affiliates of the Italian Hospital Medical Care Program, a prepaid health maintenance organization located in Buenos Aires...
June 23, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28637036/differentiating-incident-from-recurrent-stroke-using-administrative-data-the-impact-of-varying-lengths-of-look-back-periods-on-the-risk-of-misclassification
#10
John Mark Worthington, Melina Gattellari, Chris Goumas, Bin Jalaludin
BACKGROUND/AIMS: Administrative data are widely used to monitor epidemiological trends in stroke and outcomes; yet there is scant empirical guidance on how to best differentiate incident from recurrent stroke. METHODS: We identified all hospital admissions in New South Wales, Australia, with a principal stroke diagnosis from July 1, 2013 to June 30, 2014, linked to 12 years of previous admissions. We calculated the proportion of cases identified with a prior stroke to determine the number of years of look-back required to minimise misclassification of incident and recurrent strokes...
June 22, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28628919/effect-of-influenza-vaccination-on-risk-of-stroke-a-systematic-review-and-meta-analysis
#11
Kyu Rae Lee, Jeong Hun Bae, In Cheol Hwang, Kyoung Kon Kim, Heuy Sun Suh, Ki Dong Ko
BACKGROUND: Despite the presence of a strong association between influenza infection and stroke, whether influenza vaccination reduces the risk of stroke is yet a matter of controversy. We conducted a meta-analysis to determine whether influenza vaccination protects against stroke. METHODS: We searched PubMed, EMBASE, and the Cochrane Library from database inception date to November 18, 2016, without language restrictions, to identify studies investigating the effect of influenza vaccination on subsequent risk of stroke...
June 21, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28586776/mortality-of-stroke-and-its-subtypes-in-china-results-from-a-nationwide-population-based-survey
#12
Zhenghong Chen, Bin Jiang, Xiaojuan Ru, Haixin Sun, Dongling Sun, Xiangtong Liu, Yichong Li, Di Li, Xiuhua Guo, Wenzhi Wang
BACKGROUND: In China, stroke is the leading cause of death and contributes to a heavy disease burden. However, a nationwide population-based survey of the mortality of stroke and its subtypes is lacking for this country. METHODS: Data derived from the National Epidemiological Survey of Stroke in China, which was a multistage, stratified clustering sampling-designed, cross-sectional survey, were analyzed. Mortality rate analyses were performed for 476,156 participants ≥20 years old from September 1, 2012 to August 31, 2013...
June 7, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28892805/an-evaluation-of-the-central-nervous-system-medication-use-and-frailty-among-residents-of-aged-care-homes-in-malaysia
#13
Syed Shahzad Hasan, Chia Siang Kow, Kaeshaelya Thiruchelvam, David Weng Kwai Chong, Syed Imran Ahmed
BACKGROUND/AIMS: Old age and institutionalization in care homes are associated with increased use of risk medications affecting the central nervous system (CNS). This study evaluated medication utilization and appropriateness; and assessed frailty among residents of Malaysian aged care homes. METHODS: The subjects of this study included 202 elderly (≥65 years) residents of 17 aged care homes in suburban peninsular Malaysia. Frailty was measured using the Groningen Frailty Indicator (GFI) score and independence in daily living was measured as KATZ activity of daily living score...
2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28877525/development-of-a-thai-parkinson-s-disease-screening-tool-and-the-prevalence-of-parkinsonism-and-parkinson-s-disease-based-on-a-community-survey-in-bangkok
#14
Weerasak Muangpaisan, Pitiporn Siritipakorn, Prasert Assantachai
INTRODUCTION: Few epidemiological data of parkinsonism and Parkinson's disease (PD) exist in Southeast Asia. We aimed to develop and validate a screening tool, and investigate the prevalence of parkinsonism and PD via a community survey. METHODS: A PD-screening tool comprising 11 "yes/no" items was developed in a clinical setting and validated in the community. The prevalence of PD and parkinsonism was investigated in a survey that included PD screening tools, face-to-face interviews, and physical examinations...
2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28873374/characteristics-and-prognosis-of-oldest-old-subjects-with-amyotrophic-lateral-sclerosis
#15
Meira Dandaba, Philippe Couratier, Anaïs Labrunie, Marie Nicol, Bello Hamidou, Marie Raymondeau, Giancarlo Logroscino, Pierre Marie Preux, Benoît Marin
BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is an age-related neurodegenerative disease with unclear characteristics and prognosis in the oldest old (80 years and over). The aim of this study was to compare the oldest old and younger ALS patients in terms of clinical and socio-demographic characteristics, and prognosis. METHODS: ALS incident cases from the register of ALS in Limousin (FRALim), diagnosed between January 2000 and July 2013, were included. Descriptive and comparative analyses by age group were carried out...
2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28850949/white-matter-lesion-progression-and-cognitive-function-over-5-years-in-a-young-susceptible-population
#16
Paul A Nyquist, Lisa R Yanek, Brian G Kral, Lewis C Becker, Dhananjay Vaidya, Diane M Becker
No abstract text is available yet for this article.
2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28848208/epidemiology-of-multiple-sclerosis-in-austria
#17
Sabine Salhofer-Polanyi, Hakan Cetin, Fritz Leutmezer, Anna Baumgartner, Stephan Blechinger, Assunta Dal-Bianco, Patrick Altmann, Barbara Bajer-Kornek, Paulus Rommer, Michael Guger, Doris Leitner-Bohn, Berthold Reichardt, Farideh Alasti, Wilhelm Temsch, Tanja Stamm
BACKGROUND: To assess the incidence rate and prevalence ratio of multiple sclerosis (MS) in Austria. METHODS: Hospital discharge diagnosis and MS-specific immunomodulatory treatment prescriptions from public health insurances, covering 98% of Austrian citizens with health insurance were used to extrapolate incidence and prevalence numbers based on the capture-recapture method. RESULTS: A total of 1,392,629 medication prescriptions and 40,956 hospitalizations were extracted from 2 data sources, leading to a total of 13,205 patients...
2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28848165/strategies-to-improve-stroke-care-services-in-low-and-middle-income-countries-a-systematic-review
#18
Jeyaraj Durai Pandian, Akanksha G William, Mahesh P Kate, Bo Norrving, George A Mensah, Stephen Davis, Gregory A Roth, Amanda G Thrift, Andre P Kengne, Brett M Kissela, Chuanhua Yu, Daniel Kim, David Rojas-Rueda, David L Tirschwell, Foad Abd-Allah, Fortuné Gankpé, Gabrielle deVeber, Graeme J Hankey, Jost B Jonas, Kevin N Sheth, Klara Dokova, Man Mohan Mehndiratta, Johanna M Geleijnse, Maurice Giroud, Yannick Bejot, Ralph Sacco, Ramesh Sahathevan, Randah R Hamadeh, Richard Gillum, Ronny Westerman, Rufus Olusola Akinyemi, Suzanne Barker-Collo, Thomas Truelsen, Valeria Caso, Vasanthan Rajagopalan, Narayanaswamy Venketasubramanian, Vasiliy V Vlassovi, Valery L Feigin
BACKGROUND: The burden of stroke in low- and middle-income countries (LMICs) is large and increasing, challenging the already stretched health-care services. AIMS AND OBJECTIVES: To determine the quality of existing stroke-care services in LMICs and to highlight indigenous, inexpensive, evidence-based implementable strategies being used in stroke-care. METHODS: A detailed literature search was undertaken using PubMed and Google scholar from January 1966 to October 2015 using a range of search terms...
2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28810256/dose-response-relationship-between-the-risk-of-vasovagal-syncope-and-body-mass-index-or-systolic-blood-pressure-in-young-adults-undergoing-blood-tests
#19
Tomohide Yamada, Shintaro Yanagimoto
No abstract text is available yet for this article.
2017: Neuroepidemiology
https://www.readbyqxmd.com/read/28810247/physical-inactivity-predicts-slow-gait-speed-in-an-elderly-multi-ethnic-cohort-study-the-northern-manhattan-study
#20
Joshua Z Willey, Yeseon P Moon, Erin R Kulick, Ying Kuen Cheung, Clinton B Wright, Ralph L Sacco, Mitchell S V Elkind
INTRODUCTION: Gait speed is associated with multiple adverse outcomes of aging. We hypothesized that physical inactivity would be prospectively inversely associated with gait speed independently of white matter hyperintensity volume and silent brain infarcts on MRI. METHODS: Participants in the Northern Manhattan Study MRI sub-study had physical activity assessed when they were enrolled into the study. A mean of 5 years after the MRI, participants had gait speed measured via a timed 5-meter walk test...
2017: Neuroepidemiology
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