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Mònica Povedano, Marc Saez, Juan-Antonio Martínez-Matos, Maria Antònia Barceló
BACKGROUND: It is believed that an interaction between genetic and non-genetic factors may be involved in the development of amyotrophic lateral sclerosis (ALS). With the exception of exposure to agricultural chemicals like pesticides, evidence of an association between environmental risk factors and ALS is inconsistent. Our objective here was to investigate the association between long-term exposure to environmental factors and the occurrence of ALS in Catalonia, Spain, and to provide evidence that spatial clusters of ALS related to these environmental factors exist...
May 31, 2018: Neuroepidemiology
Valentina A Andreeva, Léopold K Fezeu, Serge Hercberg, Pilar Galan
BACKGROUND: The association between obesity and migraine has been established; however, it is unclear whether it varies by perceived stress within each gender. METHODS: This cross-sectional study used data from the ongoing NutriNet-Santé e-cohort with enrollees from the general population. Anthropometric and migraine data were provided via self-report questionnaires (2013-2016). Migraine was defined using established criteria. Perceived stress was assessed with Cohen's Perceived Stress Scale-10...
May 29, 2018: Neuroepidemiology
Kyla A McKay, Ruth Ann Marrie, John D Fisk, Scott B Patten, Helen Tremlett
BACKGROUND: Persons with multiple sclerosis (MS) use health resources with greater frequency than the general population. However, little is known regarding which patient characteristics might contribute. OBJECTIVE: The study aimed to evaluate characteristics associated with healthcare use in MS patients. METHODS: Consecutive MS clinic attendees were recruited (September-November 2010), with clinical, demographic, and patient-completed questionnaires collected at 3 visits over 2 years...
May 15, 2018: Neuroepidemiology
Moisés Rodríguez-Mañero, Estrella López-Pardo, Alberto Cordero, Omar Kreidieh, José Novo Platas, Luis Valdés, Adrian Cid-Menendez, Javier García-Seara, María Pereira-Vázquez, Jose-Luis Martínez-Sande, Alberto Ruano, Carlos Peña-Gil, Pilar Mazón, Jose María García-Acuña, José Ramón González-Juanatey
INTRODUCTION: Atrial fibrillation might increase the risk of dementia. We aim to test the hypothesis that dementia could reclassify the actual risk of stroke and death predicted by the CHA2DS2-VASc in patients with atrial fibrillation (AF). METHODS: A prospective study performed in a specific health care area. RESULTS: From our health care area (n = 348,985), throughout 2013, AF was codified in 7,990 (2.08%). Mean age was 76.83 ± 10.5, mean CHA2DS2-VASc = 3...
May 15, 2018: Neuroepidemiology
Eimear Smith, Patricia Fitzpatrick, John Murtagh, Frank Lyons, Seamus Morris, Keith Synnott
BACKGROUND: The International Spinal Cord Society and World Health Organisation recommend the collection of epidemiological data on traumatic spinal cord injury (TSCI). A 1-year prospective study is ongoing in Ireland. While the results of this study are awaited, it was concluded from a feasibility exercise that a complete retrospective dataset, 2010-2015, could be obtained and would be useful for service planning. METHODS: All patients with TSCI discharged from the national SCI acute and rehabilitation centres were included...
May 15, 2018: Neuroepidemiology
Kimberly D van der Willik, Rikje Ruiter, Frank J Wolters, M Kamran Ikram, Bruno H Stricker, Michael Hauptmann, Annette Compter, Sanne B Schagen, M Arfan Ikram
BACKGROUND: To investigate and to compare the relation between dementia and cancer with the association between mild cognitive impairment (MCI) and cancer. METHODS: A total of 13,207 persons from the Rotterdam Study were followed between 1990 and 2013 for the onset of dementia and cancer (sample 1). Between 2002 and 2005, a subset of 5,181 persons underwent extensive cognitive testing for MCI and subsequently were followed up for cancer until 2013 (sample 2). We used Cox proportional hazard models to determine the association between dementia and cancer, and MCI and cancer...
May 14, 2018: Neuroepidemiology
Ibrahim Abdollahpour, Saharnaz Nedjat, Mohammad Ali Mansournia, Mohammad Ali Sahraian, Jay S Kaufman
BACKGROUND: Adolescence is considered as a critical time period in multiple sclerosis (MS) etiology. Nonetheless, there are insufficient reports regarding the potential role of fresh and canned fish consumptions during adolescence in MS etiology. The authors investigated the association between fresh and canned fish consumptions and MS. METHODS: This was a population-based incident case-control study conducted in Tehran. Cases (n = 547) identified from Iranian Multiple Sclerosis Society between August 7, 2013, and November 17, 2015 were included in the study...
May 7, 2018: Neuroepidemiology
Sharon Lerman, Boaz Amichai, Gabriel Weinstein, Varda Shalev, Gabriel Chodick
BACKGROUND: The association between Parkinson's disease (PD) and melanoma is well recognized, but its relationship with non-melanoma skin cancers has not been studied in depth. OBJECTIVE: To assess the relationship between PD, and risk of melanoma and keratinocyte carcinoma: squamous cell carcinoma (SCC) and basal cell carcinoma (BCC). METHODS: This historical cohort study used the data of 1.2 million adult members of a large health organization between 2000 and 2015...
March 22, 2018: Neuroepidemiology
Mette Wod, Magnus Thorsten Jensen, Søren Galatius, Jacob B Hjelmborg, Gorm B Jensen, Kaare Christensen
AIMS: In order to examine the hypothesis that elevated resting heart rate (RHR) is associated with impaired cognitive score, we investigated the relationship between RHR and cognitive score in middle-aged, elderly and old Danish subjects from the general population. METHODS: Composite cognitive scores derived from the result of 5 age-sensitive cognitive tests for a total of 7,002 individuals (Middle-aged Danish twin: n = 4,132, elderly Danish twins: n = 2,104 and Danish nonagenarian: n = 766) divided according to RHR and compared using linear regression models adjusted for sex, age, previous heart conditions and hypertension...
March 22, 2018: Neuroepidemiology
Ivan Martinka, Miriam Fulova, Margita Spalekova, Peter Spalek
PURPOSE: The objective of the study was to evaluate changes of epidemiological parameters in patients with myasthenia gravis (MG) in Slovakia during the period 1977-2015. METHODS: Data from medical records of MG patients registered in Slovakia were analyzed. Epidemiological rates (incidence, prevalence, mortality) were assessed for several periods to identify changes and drifts over the period of study. RESULTS: Out of 2,074 patients, 892 were males (43...
March 20, 2018: Neuroepidemiology
Devender Bhalla, Elham Lotfalinezhad, Fatemah Amini, Mohsen Salmannejad, Vahid Reza Borhani Nezhad, Seyedeh Fatemeh Rezai Kooshalshah, Ahmed Delbari, Reza Fadayevatan, I Irmansyah, Abdalla Abdelrahman, Nanda Kumar Bhatta, Kurosh Gharagozli
BACKGROUND: The risk of dementia is reported as "epidemic" and "looming" over the Middle East and North Africa (MENA) region. For this, we performed a multi-language review and feasible analysis on the incidence of dementia to offer apt conclusions. METHODS: Totally, 3 databases (Magiran, Scientific Information Database, and PubMed) and 1 non-database source (Google) were searched in French, English, and Persian by using specific keywords and their combinations...
March 14, 2018: Neuroepidemiology
Wanying Duan, Yuesong Pan, Chunjuan Wang, Yilong Wang, Xingquan Zhao, Yongjun Wang, Liping Liu
BACKGROUND: Delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) is a significant cause of morbidity and mortality. While it is important to detect early signs of DCI, patients with high risk of DCI are difficult to identify, and the potential risk factors are uncertain. This study aimed to identify independent risk factors of DCI and clarify their clinical impact on outcome and the disease course. METHODS: For this nationwide, multicenter, prospective clinical study involving consecutive patients with aSAH recruited from the China National Stroke Registry, demographic, clinical, radiological, and laboratorial data during hospitalisation, in-hospital complications, functional outcomes, and mortality at 3, 6, and 12 months were recorded...
March 12, 2018: Neuroepidemiology
Hanzhang Xu, Truls Ostbye, Allison A Vorderstrasse, Matthew E Dupre, Bei Wu
BACKGROUND: The place of residence has been linked to cognitive function among adults in developed countries. This study examined how urban and rural residence was associated with cognitive function among adults in India. METHODS: The World Health Organization Study on Global AGEing and Adult Health data was used to examine cognition among 6,244 community-residing adults age 50+ in 6 states in India. Residential status was categorized as urban, rural, urban-to-urban, rural-to-urban, rural-to-rural, and urban-to-rural...
March 7, 2018: Neuroepidemiology
Alessio Farcomeni, Antonio Cortese, Eleonora Sgarlata, Danilo Alunni Fegatelli, Gerolama Alessandra Marfia, Fabio Buttari, Massimiliano Mirabella, Chiara De Fino, Luca Prosperini, Carlo Pozzilli, Maria Grazia Grasso, Luigi Iasevoli, Giancarlo Di Battista, Enrico Millefiorini
BACKGROUND: Limited data are available on the prevalence of multiple sclerosis (MS) in central Italy. The objective of this study is to estimate MS prevalence in the metropolitan area of Rome. METHODS: We used the capture-recapture method to calculate prevalence estimates in the study area. The selected prevalence day was December 31, 2015. A total of 1,007 patients, with a definite diagnosis of MS according to the revised McDonald's criteria, were considered for crude, age- and sex-specific prevalence estimation...
March 2, 2018: Neuroepidemiology
(no author information available yet)
No abstract text is available yet for this article.
February 22, 2018: Neuroepidemiology
Deborah C Salzberg, Joshua R Mann, Suzanne McDermott
BACKGROUND/AIMS: Duchenne Muscular Dystrophy (DMD) has childhood onset, primarily affects males, and is usually fatal before the age of 40 years. Previous studies have indicated that this X-linked condition is more prevalent in whites than in blacks, but those were based on active surveillance, and limited to smaller populations and younger ages. METHODS: US death data were used to calculate mortality rates by race and ethnicity, with MD as either the underlying or multiple cause of death (MCD)...
2018: Neuroepidemiology
Truong-Minh Pham, Khokan C Sikdar, Winson Y Cheung, Wilson Roa, Angela Eckstrand, Bethany Kaposhi, Lorraine Shack
BACKGROUND: In this study, we investigated whether there has been an improvement in premature mortality due to central nervous system (CNS) cancers among the Canadian population from 1980 through 2010. METHODS: Mortality data for CNS cancers were obtained from World Health Organization mortality database. Years of life lost (YLL) was estimated using Canadian life tables. Average lifespan shortened (ALSS) was calculated and defined as the ratio of YLL relative to the expected lifespan...
2018: Neuroepidemiology
Joseph Aked, Hossein Delavaran, Bo Norrving, Arne Lindgren
BACKGROUND: Up-to-date epidemiological stroke studies are important for healthcare planning and evaluating prevention strategies. This population-based study investigates temporal trends in stroke incidence and case-fatality in southern Sweden. METHODS: First-ever stroke cases in the local catchment area of Skåne University Hospital in Lund, Sweden, between March, 2015 and February, 2016, were included from several sources, including 2 prospective hospital-based registers, retrospective screening of primary care visits, and autopsy registers...
2018: Neuroepidemiology
Enrique C Leira, Catherine M Viscoli, Linnea A Polgreen, Mark Gorman, Walter N Kernan
BACKGROUND AND PURPOSE: Clinical trials often seek to enroll patients from both urban and rural areas to safeguard the generalizability of results. However, maintaining contact with patients who live away from a recruitment site, including rural areas, can be challenging. In this research we examine the effect of distance between patient and study centers on treatment adherence and retention. METHODS: Secondary analysis of 2,466 participants in the Insulin Resistance Intervention after Stroke trial who were enrolled from research sites in the United States...
2018: Neuroepidemiology
Marek Gierlotka, Beata Labuz-Roszak, Bogdan Wojtyniak, Anetta Lasek-Bal, Tomasz Zdrojewski, Monika Adamczyk-Sowa, Kamil Chwojnicki, Michal Skrzypek, Daniel Ciesla, Mariusz Gasior
BACKGROUND: Poland, classified as a high-income country, is still considered to have a high cardiovascular risk population. During the last decade, the standards of care in acute stroke (AS) had markedly improved; thus, we aimed to assess whether and how it translated into early and late outcomes. METHODS: Silesian Stroke Registry was created from the administrative database of the public, obligatory, health -insurer in Poland. The AS cases were selected based on primary diagnosis coded in ICD-10 as I60-I64 for years 2006-2015 (n = 120,844)...
2018: Neuroepidemiology
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