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Qi Lin, Zhiqiang Pan
No abstract text is available yet for this article.
January 10, 2019: Cornea
Sepehr Feizi, Siamak Delfazayebaher, Ali Masoudi, Zahra Babamohamadi, Mohammad Ali Javadi
PURPOSE: To compare donor lenticule thickness reported by the eye bank with lenticule thickness measured at 6 months after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: This prospective, interventional case series enrolled 30 eyes from 30 patients who underwent DSAEK using precut eye bank tissue. Preoperative thickness measurements of the donor lenticules were taken centrally and at pericentral and peripheral graft areas using an anterior segment optical coherence tomography system...
January 9, 2019: Cornea
Filippos Vingopoulos, Anastasios John Kanellopoulos
PURPOSE: To compare the outcomes and complications of Epi-Bowman blunt keratectomy (EBK) using a blunt epikeratome (Epi-Clear, Orca Surgical, Israel), with alcohol delamination of the corneal epithelium during photorefractive keratectomy (PRK) in contralateral eyes. METHODS: This prospective, randomized contralateral eye study included 44 eyes of 22 patients undergoing PRK for bilateral myopia or myopic astigmatism. In each patient, epithelial delimitation was performed using an Epi-Clear epikeratome EBK (EBK group) on 1 eye and diluted ethanol (EtOH) on the fellow eye (EtOH group)...
January 9, 2019: Cornea
Ye Elaine Wang, Tudor Cosmin Tepelus, Wei Gui, John A Irvine, Olivia L Lee, Hugo Y Hsu
PURPOSE: Acanthamoeba keratitis (AK) is a severe vision-threatening ocular infection that is frequently a diagnostic challenge. Treatment course is lengthy and often not fully effective. Contact lens wear has been recognized as the prime risk factor for AK. In vivo confocal microscopy (IVCM) is a noninvasive imaging modality that allows direct visualization of potential causative pathogens in real time with an established utility in the diagnosis of AK. In this study, we aim to assess the utility of IVCM in monitoring disease progression in contact lens wearers with culture-confirmed keratitis...
January 9, 2019: Cornea
Haitham Al-Mahrouqi, Saif Bani Oraba, Shihab Al-Habsi, Noufal Mundemkattil, Jithin Babu, Sathiya M Panchatcharam, Rashid Al-Saidi, Abdulatif Al-Raisi
PURPOSE: To investigate the validity and reliability of retinoscopy in screening for keratoconus using the rotating Pentacam Scheimpflug camera as the gold standard comparison. METHODS: Patients between the ages of 10 and 30 years who were referred to the outpatient clinic with keratoconus, keratoconus suspect, reduced vision, eye discomfort or frequent change of glasses, or for refraction or refractive surgery, were screened by two independent and masked retinoscopists for the presence of scissoring reflex...
January 9, 2019: Cornea
Kamal A M Solaiman, Wael M El-Haig, Ashraf Borʼi, Ahmad S Khalil, Ahmed M B Awad, Hani A Al-Bialy, Basem M Ibrahim
PURPOSE: To report the results of a new approach to the 2-stage surgical management of coexisting visually significant corneal opacities and cataract. METHODS: A retrospective analysis of eyes with corneal opacities and cataract that were surgically treated with simultaneous penetrating keratoplasty and cataract surgery, followed by secondary intraocular lens (IOL) implantation after removal of corneal sutures, was conducted. The parameters used for assessment were the following: mean percentage of graft endothelial cell loss after IOL implantation, deviation of the postoperative mean spherical equivalent from the target refraction, and mean uncorrected distance visual acuity (UDVA)...
January 9, 2019: Cornea
Surabhi Gupta, Ashi Khurana
No abstract text is available yet for this article.
December 31, 2018: Cornea
Prafulla K Maharana, Pranita Sahay, Ritu Nagpal
No abstract text is available yet for this article.
December 31, 2018: Cornea
Yu-Chi Liu, Valéry V Wittwer, Nur Zahirah M Yusoff, Chan Nyein Lwin, Xin Yi Seah, Jodhbir S Mehta, Theo Seiler
PURPOSE: To describe the feasibility and outcomes of intraoperative optical coherence tomography (OCT)-guided, femtosecond laser-assisted deep anterior lamellar keratoplasty in which the lamellar and tunnel cuts were completed by laser. METHODS: The Ziemer Z8 system was used to scan the corneas intraoperatively and guide the stromal lamellar and tunnel cuts created by the laser. Thirty porcine eyes and 3 human cadaver globes were used to evaluate the accuracy of laser-created intrastromal tunnels and the feasibility of achieving big-bubble pneumatic dissection...
December 31, 2018: Cornea
Rolake O Alabi, Amy Ansin, Jameson Clover, John Wilkins, Naveen K Rao, Mark A Terry, Khoa D Tran, Christopher S Sales
PURPOSE: To determine the feasibility of using telemedicine consultations in the evaluation of recovered donor corneas for transplant suitability. METHODS: This study aims to establish and test the minimum imaging requirements for telemedical consultations of corneal tissue by remote eye bank medical directors. Digital images from the slit lamp, optical coherence tomography, and/or specular microscope were assembled into telemedical consults and emailed to 4 eye bank medical directors (M...
December 31, 2018: Cornea
Tien-En Tan, Donald Tiang Hwee Tan
PURPOSE: To describe 4 cases of cytomegalovirus (CMV) corneal endotheliitis occurring after Descemet membrane endothelial keratoplasty (DMEK). METHODS: This is a retrospective, interventional case series. Case records of 4 patients (one eye each) diagnosed with CMV corneal endotheliitis after DMEK were reviewed retrospectively. Presenting clinical features, treatment, and outcomes were examined. RESULTS: Patients' age ranged from 68 to 77 years...
December 31, 2018: Cornea
Sophie X Deng, Vincent Borderie, Clara C Chan, Reza Dana, Francisco C Figueiredo, José A P Gomes, Graziella Pellegrini, Shigeto Shimmura, Friedrich E Kruse
PURPOSE: Despite extensive knowledge gained over the last 3 decades regarding limbal stem cell deficiency (LSCD), the disease is not clearly defined, and there is lack of agreement on the diagnostic criteria, staging, and classification system among treating physicians and research scientists working on this field. There is therefore an unmet need to obtain global consensus on the definition, classification, diagnosis, and staging of LSCD. METHODS: A Limbal Stem Cell Working Group was first established by The Cornea Society in 2012...
December 31, 2018: Cornea
Tsontcho Ianchulev, Stephen Lane, Marisse Masis, Jonathan H Lass, Beth Ann Benetz, Harry J Menegay, Francis W Price, Shan Lin
PURPOSE: To evaluate corneal endothelial cell density (ECD) and morphology 2 years after phacoemulsification in subjects from the COMPASS trial (, NCT01085357) who had mild-to-moderate primary open-angle glaucoma and visually significant cataracts. METHODS: The central corneal endothelium was evaluated by serial specular microscopy at 0 to 24 months. ECD, coefficient of variation, and percentage of hexagonal cells were evaluated by a central image analysis reading center and central corneal thickness (CCT) was evaluated by ultrasound pachymetry...
December 31, 2018: Cornea
Mengliang Wu, Xin Liu, Jing Han, Tingting Shao, Yan Wang
PURPOSE: To evaluate sleep and mood status in patients with dry eye disease (DED) and analyze the association between sleep quality, mood status, and ocular surface characteristics. METHODS: Consecutive patients with DED (N = 106) and age- and sex-matched healthy controls (N = 50) were enrolled. Tear fluid break up time (TBUT), corneal fluorescein staining, and Schirmer I tests were performed in the order listed here to evaluate dry eye. A visual analog scale was used to assess dry eye symptom severity...
December 31, 2018: Cornea
Kara C LaMattina, Robert S Feder, Anjum F Koreishi, Debra A Goldstein
PURPOSE: To report a case of partial scleral rupture after laser in situ keratomileusis (LASIK) surgery. METHODS: This is a retrospective case report describing a late complication of LASIK surgery. RESULTS: A 32-year-old white woman with a history of LASIK surgery performed with a mechanical microkeratome 4 years previously presented for evaluation of partial bilateral scleral ruptures. An arcuate filtering bleb along the contour of the cornea was found on the right eye with associated hypotony and corneal astigmatism...
December 28, 2018: Cornea
Kristin J Mathes, Khoa D Tran, Zachary M Mayko, Christopher G Stoeger, Michael D Straiko, Mark A Terry
PURPOSE: To examine postoperative reports of infection rates for eye bank-prepared and non-eye bank-prepared corneas from January 1, 2006 to December 31, 2017, from a single eye bank. METHOD: A retrospective review of reported fungal and bacterial infections with corneal transplant surgeries using corneas distributed by our eye bank was conducted. The reported number of infections for corneas that underwent eye bank preparation (pre-cut and pre-stripped corneas) and for those distributed without eye bank preparation was quantified...
December 28, 2018: Cornea
Hiroaki Kato, Norihiko Yokoi, Akihide Watanabe, Aoi Komuro, Yukiko Sonomura, Chie Sotozono, Shigeru Kinoshita
PURPOSE: Considering that tears play the role of a lubricant, it is speculated that in the pathophysiology of dry eye, increased friction during blinking results in corneal and conjunctival damage, which may subsequently affect the blink. The purpose of this study was to investigate the relationship between ocular surface epithelial damage, tear abnormalities, and blinks in patients with dry eye. METHODS: This study involved 45 eyes of 45 female patients with dry eye (mean age: 57...
December 28, 2018: Cornea
Wassef Chanbour, Israa Mokdad, Abdallah Mouhajer, Elias Jarade
PURPOSE: To report the incidence, characteristics, clinical presentations, risk factors, and the available treatment modalities of sterile peripheral ulcerative keratitis (PUK) post-corneal collagen crosslinking (CXL). METHODS: This study is a retrospective study including 771 eyes of 474 patients operated for keratoconus or ectasia after LASIK between January 2010 and June 2017 at Beirut Eye & ENT Specialist hospital. The average follow-up period was 4.2 years with a minimum of 1 year post-CXL...
December 28, 2018: Cornea
Joao Crispim, Norma Allemann, Joelle A Hallak, Dimitri T Azar, Jose De La Cruz
PURPOSE: To compare direct and indirect LASIK flap thickness measurements using ultrasound and Scheimpflug technology. METHODS: Eighty-two eyes treated with laser-assisted in situ keratomileusis refractive surgery using a femtosecond laser (IntraLase FS150) were prospectively included in the study. Flap thickness was set to 115 μm. Corneal flap thickness was measured using the direct method-ie, ultrasound pachymetry immediately after flap construction in the presence of cavitation bubbles-and indirect methods, with subtraction of intraoperative post-lift corneal thickness measured using ultrasound pachymetry (intrastroma) from preoperative central corneal thickness using ultrasound (Indirect-US) or Scheimpflug thinnest pachymetry (Indirect-Scheimpflug)...
December 28, 2018: Cornea
Tantai Zhao, Zhixue Fang, Jiao Tian, Jia Liu, Yangyan Xiao, Huiling Li, Baihua Chen
PURPOSE: This study analyzes images of Kayser-Fleischer (K-F) rings in patients with Wilson disease (WD) using in vivo confocal microscopy (IVCM) and explores whether IVCM can be a useful clinical tool in facilitating the diagnosis and characterization of K-F rings. METHODS: One hundred four eyes of 52 patients with WD and K-F rings (K-F group) and 52 normal eyes of 52 age- and gender-matched control subjects (control group) were enrolled in the study. Both K-F and control groups consisted of 29 male patients and 23 female patients...
December 28, 2018: Cornea
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