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Cornea

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https://www.readbyqxmd.com/read/28410356/water-exposure-is-a-common-risk-behavior-among-soft-and-gas-permeable-contact-lens-wearers
#1
Aaron B Zimmerman, Kathryn Richdale, Gladys Lynn Mitchell, Beth T Kinoshita, Dawn Y Lam, Heidi Wagner, Luigina Sorbara, Robin L Chalmers, Sarah A Collier, Jennifer R Cope, Maya M Rao, Michael J Beach, Jonathan S Yoder
PURPOSE: To understand soft contact lens (SCL) and gas-permeable (GP) lens wearers' behaviors and knowledge regarding exposure of lenses to water. METHODS: The Contact Lens Risk Survey (CLRS) and health behavior questions were completed online by a convenience sample of 1056 SCL and 85 GP lens wearers aged 20 to 76 years. Participants were asked about exposing their lenses to water and their understanding of risks associated with these behaviors. Chi-square analyses examined relationships between patient behaviors and perceptions...
April 13, 2017: Cornea
https://www.readbyqxmd.com/read/28410355/descemetorhexis-without-graft-placement-for-the-treatment-of-fuchs-endothelial-dystrophy-preliminary-results-and-review-of-the-literature
#2
Alfonso Iovieno, Alberto Neri, Anna Maria Soldani, Chantal Adani, Luigi Fontana
PURPOSE: To report our preliminary experience with a central descemetorhexis without graft placement in Fuchs endothelial corneal dystrophy (FECD) and to review the existing literature on the topic. METHODS: A 4-mm central descemetorhexis was performed in 5 patients (4 women, 1 man; mean age: 69.8 ± 8.6 yrs; range: 57-78 yrs) with FECD. All patients had central confluent guttae, undetectable central endothelial cell count, healthy peripheral corneal endothelium, no clinically evident bullous keratopathy, and no ocular comorbidities...
April 13, 2017: Cornea
https://www.readbyqxmd.com/read/28410354/effects-of-tear-film-lipid-layer-thickness-and-blinking-pattern-on-tear-film-instability-after-corneal-refractive-surgery
#3
Qingzhong Chen, Min Li, Ying Yuan, Rao Me, Yunjie Yu, Guangsen Shi, Xin Wang, Bilian Ke
PURPOSE: To investigate associations between changes in tear film instability and the lipid layer thickness (LLT) and blink pattern after corneal refractive surgery (CRS). METHODS: Forty patients were enrolled in this study. The LLT and blink pattern were evaluated 1 week before and 30 days after CRS using a novel interferometer and an ocular surface disease index (OSDI) questionnaire, and other tear film stability markers were also evaluated. RESULTS: Mean OSDI scores increased from 5...
April 13, 2017: Cornea
https://www.readbyqxmd.com/read/28410548/two-year-clinical-outcome-of-500-consecutive-cases-undergoing-descemet-membrane-endothelial-keratoplasty
#4
Jorge Peraza-Nieves, Lamis Baydoun, Isabel Dapena, Abbas Ilyas, Laurence E Frank, Salvatore Luceri, Lisanne Ham, Silke Oellerich, Gerrit R J Melles
PURPOSE: To evaluate the clinical outcome of 500 consecutive cases up to 2 years after Descemet membrane endothelial keratoplasty (DMEK) and to assess which parameters may have influenced the clinical outcome. METHODS: From a group of 500 eyes (393 patients), which underwent DMEK for Fuchs endothelial corneal dystrophy (FECD), bullous keratopathy, failed corneal transplants and other indications, clinical outcomes [best-corrected visual acuity (BCVA), central endothelial cell density (ECD), and central corneal thickness] were evaluated before, and at 6, 12, and 24 months after DMEK and postoperative complications were documented...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28410361/rates-of-intraocular-pressure-elevation-and-use-of-topical-antihypertensive-medication-after-descemet-stripping-automated-endothelial-keratoplasty
#5
Mona Kaleem, Faisal Ridha, Zryan Shwani, Bonnielin Swenor, Jeffrey Goshe, Annapurna Singh
PURPOSE: To investigate intraocular pressure (IOP) elevation and medication augmentation after Descemet stripping automated endothelial keratoplasty (DSAEK) in those with and without glaucoma. METHODS: The records of 379 patients who underwent DSAEK at the Cleveland Clinic Foundation between January 2009 and 2014 were retrospectively reviewed. Postoperative IOP elevations were considered significant if IOP was ≥22 mm Hg on at least 1 follow-up visit or if it increased by ≥10 mm Hg from baseline...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28410360/estimation-of-prevalence-of-meibomian-gland-dysfunction-in-japan
#6
Shiro Amano, Kenji Inoue
PURPOSE: To estimate the prevalence of meibomian gland dysfunction (MGD) in the Japanese population using new diagnostic criteria, including lid margin abnormalities and signs of occlusion of the meibomian gland orifices as essential signs. METHODS: The participants were consecutive patients scheduled for cataract surgery at Inouye Eye Hospital. All participants were aged 50 years or older. The participants completed a symptoms questionnaire and underwent a comprehensive slit-lamp examination...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28410359/intraoperative-s-stamp-enabled-rescue-of-3-inverted-descemet-membrane-endothelial-keratoplasty-grafts
#7
Peter B Veldman, Zachary M Mayko, Michael D Straiko, Mark A Terry
PURPOSE: To report the clinical outcomes of 3 Descemet membrane endothelial keratoplasty (DMEK) grafts, in which an upside down DMEK graft orientation was discovered after SF6 gas insufflation of the anterior chamber and the orientation was then corrected intraoperatively. METHODS: A total of 371 consecutive DMEK cases using an S-stamp were analyzed and found to include 3 cases in which the DMEK graft was initially elevated with SF6 gas in an upside down orientation, as demonstrated intraoperatively by the S-stamp...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28410358/reactivation-of-herpes-zoster-keratitis-with-corneal-perforation-after-zoster-vaccination
#8
Andre Jastrzebski, Seymour Brownstein, Setareh Ziai, Solin Saleh, Kay Lam, W Bruce Jackson
PURPOSE: We present a case of reactivated herpes zoster keratouveitis of 6 years duration with corneal perforation requiring penetrating keratoplasty shortly after inoculation with herpes zoster vaccine (Zostavax, Merck, Quebec, Canada). METHODS: Retrospective case report. RESULTS: A 67-year-old woman with a 5-year history of recurrent unilateral herpes zoster keratouveitis in her right eye presented with another recurrence 2 weeks after Zostavax vaccination...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28410357/donor-endothelial-cell-count-does-not-correlate-with-descemet-stripping-automated-endothelial-keratoplasty-transplant-survival-after-2-years-of-follow-up
#9
Ivan O Potapenko, Branka Samolov, Margareta Claesson Armitage, Berit Byström, Jesper Hjortdal
PURPOSE: To analyze the influence of low endothelial cell density (ECD) of donor cornea tissue, donor age, and sex on the transplant survival rate after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: Graft ECD, age, and sex of donors used for DSAEK (n = 1789) during 7 years (2007-2014) in 4 Scandinavian hospitals were assessed for potential association with transplant survival at 2 years of follow-up using a Cox regression model correcting for confounding factors...
April 12, 2017: Cornea
https://www.readbyqxmd.com/read/28399039/characterization-of-corneal-involvement-in-eyes-with-mucous-membrane-pemphigoid-by-in-vivo-confocal-microscopy
#10
Tudor C Tepelus, Jianyan Huang, SriniVas R Sadda, Olivia L Lee
PURPOSE: To describe the morphological features of the corneal epithelial layers, subbasal nerve plexus, stroma, and endothelium in patients with mucous membrane pemphigoid (MMP) as shown by in vivo confocal microscopy (IVCM). METHODS: Central corneal images were captured from 10 healthy age-matched control eyes and 30 eyes with clinically diagnosed MMP by in vivo laser scanning confocal microscopy (HRT III RCM). Morphological changes of the corneal epithelial layers, stroma, and endothelium, characteristics of corneal nerves, and presence of inflammatory dendritic cells (DCs) were evaluated...
April 10, 2017: Cornea
https://www.readbyqxmd.com/read/28399038/intraoperative-optical-coherence-tomography-assisted-descemet-stripping-automated-endothelial-keratoplasty-for-anterior-chamber-fibrous-ingrowth
#11
Tarek A Shazly, Lillian K To, Ian P Conner, Ladan Espandar
PURPOSE: Here, we present the first reported case of intraoperative optical coherence tomography (OCT)-assisted Descemet membrane stripping automated endothelial keratoplasty (DSAEK) in a patient with anterior segment fibrous ingrowth. METHODS: A 61-year-old woman with corneal edema and chronic angle-closure glaucoma secondary to fibrous ingrowth after 2 glaucoma shunt device implantations underwent dissection and removal of anterior chamber fibrous ingrowth and DSAEK...
April 10, 2017: Cornea
https://www.readbyqxmd.com/read/28399037/ocular-argyrosis-mimicking-conjunctival-melanoma
#12
Irwin Tendler, Melissa P Pulitzer, Victor Roggli, David H Abramson, Brian P Marr
PURPOSE: To present a novel case of ocular argyrosis mimicking conjunctival melanoma. METHODS: A 48-year-old man who is a jewelry manufacturer presented with raised pigmented lesions in the inferior fornices of both eyes. Brown-black colored, follicle-like, masses were observed in both fornices. RESULTS: An incisional biopsy confirmed the presence of silver and the diagnosis of ocular argyrosis. CONCLUSIONS: Despite its limited negative health effects, ocular argyrosis should be considered in the differential diagnosis of conjunctival pigmented lesions because of the potential for misidentification of neoplastic growth...
April 10, 2017: Cornea
https://www.readbyqxmd.com/read/28399036/implications-for-ophthalmic-formulations-ocular-buffers-show-varied-cytotoxic-impact-on-human-corneal-limbal-and-human-conjunctival-epithelial-cells
#13
Nadine Schuerer, Elisabeth Stein, Aleksandra Inic-Kanada, Marion Pucher, Christine Hohenadl, Nora Bintner, Ehsan Ghasemian, Jacqueline Montanaro, Talin Barisani-Asenbauer
PURPOSE: To investigate toxicity associated with buffers commonly used in topical ocular drug formulations using a human corneal-limbal epithelial (HCLE) and a human conjunctival epithelial (HCjE) cell model. METHODS: HCLE and HCjE cells were incubated for 10, 30, or 60 minutes with 4 different buffers based on borate, citrate, phosphate, and Tris-HCl at 10, 50, and 100 mM concentrations. To detect possible delayed effects on cell viability, after 60 minutes of buffer incubation, cells were further incubated for 24 hours with a cell medium...
April 10, 2017: Cornea
https://www.readbyqxmd.com/read/28399035/comparative-evaluation-of-tacrolimus-versus-interferon-alpha-2b-eye-drops-in-the-treatment-of-vernal-keratoconjunctivitis-a-randomized-double-masked-study
#14
Habibollah Zanjani, Mohammad Naim Aminifard, Abdolhossein Ghafourian, Mohsen Pourazizi, Alireza Maleki, Mohammed Arish, Mahnaz Shahrakipoor, Mohammad Reza Rohani, Mojtaba Abrishami, Ehsan Khafri Zare, Farhad Barzegar Jalali
PURPOSE: Vernal keratoconjunctivitis (VKC) is a bilateral, chronic, external ocular inflammatory disorder that mainly affects patients in their first or second decade. This study was designed to compare tacrolimus and interferon alpha-2b (IFN alpha-2b) eye drops in the treatment of VKC. METHODS: In this randomized, double-masked clinical trial, 40 consecutive patients with VKC were sent to a referral eye hospital in a tropical region southeast of Iran. Patients were randomly assigned to receive either 0...
April 10, 2017: Cornea
https://www.readbyqxmd.com/read/28376025/simultaneous-keratolimbal-autograft-and-penetrating-autokeratoplasty-a-single-stage-procedure-to-restore-monocular-vision-of-a-blind-patient-with-limbal-stem-cell-deficiency
#15
Elias Jarade, Mazen Amro, Ali A Haydar, Adib Hemade
PURPOSE: To describe the technique of simultaneous keratolimbal autograft and penetrating autokeratoplasty to restore monocular vision of a blind patient with limbal stem cell deficiency (LSCD). METHODS: A patient with acquired monocular vision due to loss of the left eye owing to LSCD postblast injury presented with acute loss of vision in the right eye due to central retinal artery occlusion. Simultaneous keratolimbal autograft and penetrating autokeratoplasty were performed in attempt to restore his vision in the left eye...
April 3, 2017: Cornea
https://www.readbyqxmd.com/read/28368995/proposal-for-a-novel-severity-grading-system-for-pterygia-based-on-corneal-topographic-data
#16
Kazunori Miyata, Keiichiro Minami, Atsushi Otani, Tadatoshi Tokunaga, Shouta Tokuda, Shiro Amano
PURPOSE: To propose a grading system of pterygium severity based on corneal higher-order irregularity (HOI) and to evaluate postoperative changes in corneal irregularity of the graded pterygia. METHODS: In 268 eyes of 226 patients undergoing excision surgery of primary nasal pterygium, Placido corneal topography images were taken before and until 6 months after surgery. The best-corrected visual acuity (BCVA) and pterygium size with respect to the corneal diameter were also measured...
March 31, 2017: Cornea
https://www.readbyqxmd.com/read/28368994/revisiting-the-cornea-and-trabecular-meshwork-junction-with-2-photon-excitation-fluorescence-microscopy
#17
Catherine M Marando, Choul Yong, Jason A Liao, Jimmy K Lee, Roy S Chuck
PURPOSE: To investigate the collagen and elastin architecture at the junction of the human cornea and trabecular meshwork (TM). METHODS: The cornea, TM, and ciliary body (CB) tendons of unfixed human corneal buttons were imaged with an inverted 2-photon excited fluorescence microscope (FluoView FV-1000; Olympus, Central Valley, PA). The laser (Ti:sapphire) was tuned to 850 nm for 2-photon excitation. Backscatter signals of second harmonic generation and autofluorescence were collected through a 425/30-nm emission filter and a 525/45-nm emission filter, respectively...
March 31, 2017: Cornea
https://www.readbyqxmd.com/read/28368993/penetrating-keratoplasty-at-a-tertiary-referral-center-in-ethiopia-indications-and-outcomes
#18
Menen Ayalew, Yonas Tilahun, Doug Holsclaw, Maanasa Indaram, Nicole E Stoller, Jeremy D Keenan, Jennifer Rose-Nussbaumer
PURPOSE: To describe the indications, visual acuity outcomes, and graft survival after penetrating keratoplasty (PKP) in Addis Ababa, Ethiopia. METHODS: The medical records of patients who underwent PKP at Menelik II Hospital between September 2000 and September 2013 were retrospectively reviewed. The prespecified outcomes were graft survival, visual acuity, and complication rates. RESULTS: A total of 321 patients underwent PKP during the study period and were included in the analysis...
March 31, 2017: Cornea
https://www.readbyqxmd.com/read/28368992/validation-of-an-objective-keratoconus-detection-system-implemented-in-a-scheimpflug-tomographer-and-comparison-with-other-methods
#19
Irene Ruiz Hidalgo, Jos J Rozema, Alain Saad, Damien Gatinel, Pablo Rodriguez, Nadia Zakaria, Carina Koppen
PURPOSE: To validate a recently developed program for automatic and objective keratoconus detection (Keratoconus Assistant [KA]) by applying it to a new population and comparing it with other methods described in the literature. METHODS: KA uses machine learning and 25 Pentacam-derived parameters to classify eyes into subgroups, such as keratoconus, keratoconus suspect, postrefractive surgery, and normal eyes. To validate this program, it was applied to 131 eyes diagnosed separately by experienced corneal specialists from 2 different centers (Fondation Rothschild, Paris, and Antwerp University Hospital [UZA])...
March 31, 2017: Cornea
https://www.readbyqxmd.com/read/28368991/ocular-surface-parameters-predicting-patient-satisfaction-after-a-single-vectored-thermal-pulsation-procedure-for-management-of-symptomatic-meibomian-gland-dysfunction
#20
Allister Gibbons, Daniel Waren, Nilufer Yesilirmak, Kendra Davis, Felipe Valenzuela, Juan C Murillo, Victor L Perez
PURPOSE: To evaluate the ocular surface parameters that could predict patient satisfaction after single application of vectored thermal pulsation (VTP). METHODS: This is a retrospective interventional case series; it included consecutive patients who underwent bilateral VTP for management of symptomatic meibomian gland dysfunction (MGD). Patients received a full ocular surface evaluation. The outcome was patient subjective improvement during the first 3-4 months after 3 follow-up visits...
March 31, 2017: Cornea
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