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Larysa Tutchenko, Sudi Patel, Olha Horak, Volodymyr Sanin, Serhii Kosuba
PURPOSE: To noninvasively estimate the refractive index (RI) of the central cornea along the antero-posterior direction before and after routine phacoemulsification. METHODS: Using 2 setups for a standard optical pachymeter, the ratio of observed optical section widths (OSWs) is a function of the RI. Thus, the corneal RI could be estimated using a calibration equating OSW ratios with known RI values. The OSW was measured by 2 observers for 1) normal subjects for estimating interoperator errors and effects of sex and age on the RI and 2) before and after patients underwent routine phacoemulsification...
July 12, 2018: Cornea
Soosan Jacob, Smita Narasimhan, Amar Agarwal, Jambulingam Sambath, Govindharaj Umamaheshwari, Areeckal Incy Saijimol
PURPOSE: To report primary treatment of acute corneal hydrops (CH) with a modified technique of predescemetic deep anterior lamellar keratoplasty (pdDALK). METHODS: This prospective interventional case series included 9 eyes with acute CH that underwent pdDALK as primary treatment. Technique modifications included a bevel-up needle, creating tissue emphysema as a guide for dissection, using small aliquots of air directed away from break, manual deeper dissection using a blunt dissector, centripetal dissection leaving the area of Descemet membrane (DM) break for last, retention of minimal stroma above DM tear, and tamponade of DM tear with air in the anterior chamber...
July 11, 2018: Cornea
Reiko Arita, Takanori Mizoguchi, Shima Fukuoka, Naoyuki Morishige
PURPOSE: To evaluate the efficacy of intense pulsed light (IPL) therapy combined with meibomian gland expression (MGX) for refractory meibomian gland dysfunction (MGD) in a prospective study conducted at 3 sites in Japan. METHODS: Patients with refractory obstructive MGD were enrolled and underwent 4 to 8 IPL-MGX treatment sessions at 3-week intervals. Clinical assessment included the Standard Patient Evaluation of Eye Dryness questionnaire; noninvasive breakup time of the tear film and interferometric fringe pattern as determined by tear interferometry; lid margin abnormalities, fluorescein breakup time of the tear film, corneal and conjunctival fluorescein staining (CFS), and meibum grade as evaluated with a slit-lamp microscope; meibomian gland morphology (meiboscore); and tear production as measured by the Schirmer test without anesthesia...
July 10, 2018: Cornea
Danielle Lo, Lucy Cobbs, Michael Chua, Joshua Young, Ilyse D Haberman, Yasha Modi
PURPOSE: To report a case of bilateral toxic corneal and conjunctival epitheliopathy secondary to administration of filter paper impregnated with lysergic acid diethylamide (LSD) in the inferior conjunctival fornices. METHODS: This is a single case report of an 18-year-old man who presented to the emergency department with acute, bilateral eye pain and redness of 24 hours. The patient admitted to placing folded strips of blotting paper impregnated with LSD into the inferior fornices of his eyes the previous night...
July 10, 2018: Cornea
David C Paik, Stephen L Trokel, Leejee H Suh
No abstract text is available yet for this article.
July 10, 2018: Cornea
Toshiki Shimizu, Takahiko Hayashi, Kentaro Yuda, Hidenori Takahashi, Itaru Oyakawa, Kenichiro Yamazaki, Nobuhisa Mizuki, Naoko Kato
PURPOSE: To evaluate the frequency and severity of iris posterior synechiae after Descemet membrane endothelial keratoplasty (DMEK) and to investigate possible causes of iris posterior synechiae. METHODS: Twenty-three eyes were investigated in 20 Asian patients who underwent DMEK 1 month after phacoemulsification and intraocular lens implantation surgery. A preexisting iris damage score was defined by iris damage and classified into 5 grades. Six months after DMEK, the iris posterior synechiae severity score was evaluated based on the extent of posterior synechiae, according to every 45 degrees of the pupillary rim (posterior synechiae score, 0-8)...
July 10, 2018: Cornea
Albert Y Cheung, Enrica Sarnicola, Medi Eslani, Khaliq H Kurji, Brad M Genereux, Amit Govil, Edward J Holland
PURPOSE: To describe the rate, clinical/microbiological characteristics, and outcomes of infectious keratitis in eyes with limbal stem cell deficiency after ocular surface stem cell transplantation (OSST). METHODS: In this retrospective chart review of 278 eyes that underwent OSST between January 2006 and December 2016, eyes treated for previous infectious keratitis (bacterial, fungal, or viral) were included. Demographics, risk factors, course, microbiological characteristics, and outcomes were assessed...
July 10, 2018: Cornea
Da-Hu Wang, Xin-Quan Liu, Xiao-Jun Hao, Yin-Jian Zhang, Hua-Ying Zhu, Zhi-Guo Dong
PURPOSE: To investigate the effect of the meibomian gland squeezer for treatment of meibomian gland dysfunction (MGD). METHODS: Seventy patients (140 eyes) with MGD were randomly divided into 2 groups: 36 patients who were treated by the meibomian gland squeezer as the treatment group and 34 patients were selected as the control group. Patients were evaluated at baseline, and 2-week and 1-month visits for subjective symptoms, objective signs and pain assessments, including ocular symptom scores, Ocular Surface Disease Index, tear breakup time, corneal fluorescein staining, Schirmer scores with no anesthetic (Schirmer I test), meibum quality, meibum expressibility, and Numeric Rating Scale-11...
July 10, 2018: Cornea
(no author information available yet)
No abstract text is available yet for this article.
July 6, 2018: Cornea
Tommy C Y Chan, Jason C K Chan, Yu Meng Wang, Christopher J Rapuano
PURPOSE: To evaluate the history of densitometric data in patients with keratoconus undergoing corneal cross-linking. METHODS: Twenty-two eyes of 22 patients with keratoconus were included. Corneal tomography and densitometry measurements were performed before and after accelerated corneal cross-linking. The duration of corneal haze was defined as the time between cross-linking and densitometry measurements returning to the preoperative value. Survival analysis of corneal haze after cross-linking was performed...
July 6, 2018: Cornea
Swati Singh, Ruchi Mittal, Arnav Ghosh, Devjyoti Tripathy, Suryasnata Rath
PURPOSE: To evaluate the imaging characteristics of intraepithelial and invasive ocular surface squamous neoplasia (OSSN) on high-resolution anterior segment optical coherence tomography (ASOCT). METHODS: In this prospective cross-sectional study, 17 consecutive patients (10 intraepithelial and 7 invasive) with histopathologically proven OSSN were included. All patients underwent slit-lamp imaging and time-domain ASOCT at premarked sites. Management included standard complete surgical excision with margin clearance and cryotherapy for all cases...
July 6, 2018: Cornea
Mohammad Ali Javadi, Sepehr Feizi, Saeed Rahmani, Pejman Khajuee-Kermani
PURPOSE: To evaluate the long-term stability of subjective refraction after deep anterior lamellar keratoplasty (DALK) performed in keratoconus-affected eyes. METHODS: This retrospective, comparative interventional case series analyzed the data of 73 eyes in 69 patients with keratoconus who underwent DALK. Only patients with clear grafts who had all sutures removed for at least 12 months were enrolled. The corrected distance visual acuity (CDVA) and manifest refraction were measured several months after all sutures were removed...
July 3, 2018: Cornea
Manli Liu, Huan Wang, Haiqin Lin, Quan Liu
PURPOSE: To identify and develop an efficient technique to separate the lenticule edge in small incision lenticule extraction (SMILE). METHODS: Four hundred eyes of 400 consecutive patients with myopia assigned to receive SMILE were included in the study. Eyes with poor-quality laser treatment were excluded, and the second eye of the same patient was included. Two skilled surgeons performed SMILE in the Zhongshan Ophthalmic Center. Each surgeon was allotted 200 patients...
July 3, 2018: Cornea
Nidhi Gupta, Javed Hussain Farooqui, Nikunj Patel, Umang Mathur
PURPOSE: To evaluate clinical outcomes of sequential PKP in eyes with unilateral chemical injury, which have previously undergone autologous simple limbal epithelial transplantation (SLET) at a tertiary eye center in North India. METHODS: This is a single-center, retrospective, noncomparative interventional case series reviewing patients with unilateral limbal stem cell deficiency treated by SLET and sequential PKP between 2012 and 2017. The primary outcome was defined as allograft survival, defined as a completely epithelialized, clear, avascular graft...
July 2, 2018: Cornea
Aida Madzak, Jesper Hjortdal
PURPOSE: Organ culture is the most common method for preservation of human donor corneas within Europe, and the maximum accepted storage period is typically set to 4 weeks. However, little is known about the fate of prolonged (4+ wks) organ culture storage of donor corneas. The aim of this study was to evaluate the clinical outcomes of corneal grafts preserved from 4 to 7 weeks compared with corneal grafts preserved up to 4 weeks in organ culture medium. METHODS: A registry study was performed, identifying 1252 corneal transplantations [Descemet stripping automated endothelial keratoplasty (DSAEK) and penetrating keratoplasty (PKP)] between February 2008 and November 2015 at Aarhus University Hospital, Denmark...
June 28, 2018: Cornea
Lara R Newman, George O D Rosenwasser
PURPOSE: To evaluate the utility, safety, and efficacy of a parallel or cloverleaf retention suture in Descemet stripping automated endothelial keratoplasty that does not penetrate donor tissue and can be removed at the slit lamp for patients at high risk of graft detachment. METHODS: Data were prospectively collected over 9 years from patients who received a retention suture. Indications for use of a retention suture included difficulty with postoperative positioning, abnormal intraocular anatomy including glaucoma tube shunts, trabeculectomies, anterior chamber intraocular lens implants, previous vitrectomy, aniridia, and aphakia, or history of previous graft detachment...
June 28, 2018: Cornea
Naoki Okumura, Ryota Inoue, Shinichiro Nakano, Hirofumi Imai, Daiki Matsumoto, Kanae Kayukawa, Koichi Wakimasu, Koji Kitazawa, Noriko Koizumi, Shigeru Kinoshita
PURPOSE: The aim of this study was to investigate the existence of presumed immune cells observed by contact specular microscopy in patients who underwent penetrating keratoplasty (PK) and Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: This cross-sectional study was conducted on consecutive patients who underwent follow-up visits between January and March 2015 for previously performed PK or DSAEK. Presumed immune cell-suspected "cell-like white dots" were evaluated by scanning slit contact specular microscopy...
June 26, 2018: Cornea
Mohammed Iqbal, Ahmed Elmassry, Ahmed Tawfik, Mervat Elshabrawy Elgharieb, Osama Mohiey El Deen Al Nahrawy, Ashraf Hassan Soliman, Hisham A Saad, Hosam A Ibrahim Elzembely, Ahmed Mohamed Saeed, Osama Ali Mohammed, Ahmed Gad Kamel, Islam Saad El Saman
PURPOSE: To evaluate the effectiveness and safety of combined epithelium-off cross-linking (CXL) with photorefractive keratectomy (CXL Plus) for correction of the myopic and astigmatic components of keratoconus. METHODS: Seventy-nine eyes of 46 patients who underwent CXL Plus were enrolled in this retrospective, multicenter, noncomparative clinical study. Uncorrected distance visual acuity, corrected distance visual acuity, refraction, keratometry, and pachymetry measurements were recorded preoperatively and at 3, 6, 12, and 18 months during follow-up...
June 26, 2018: Cornea
Dan Fu, Lin Wang, Xingtao Zhou, Zhiqiang Yu
PURPOSE: To compare the functional optical zone (OZ) with different levels of myopia and different OZ groups after small-incision lenticule extraction. METHODS: This retrospective study included 249 patients (120 men) after small-incision lenticule extraction correction. We grouped participants according to attempted correction [low: spherical equivalent (SE) > -3.0 D; moderate: -6.0 D ≥ SE ≥ -3.0 D; high: SE ≥ -6.0 D] and planned functional optical zone (PFOZ) (OZ-1: PFOZ ≤ 6...
June 20, 2018: Cornea
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