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Journal of the American College of Nutrition

Ana Pantovic, Manja Zec, Milica Zekovic, Radmila Obrenovic, Sanja Stankovic, Maria Glibetic
OBJECTIVE: Vitamin D (vitD) mediates numerous health conditions other than bone health and mineralization. Its role in cardiometabolic condition is still inconclusive. METHODS: We conducted a cross-sectional study in 87 apparently healthy Serbian adults. We assessed their dietary intake, anthropometric and biochemical parameters, blood pressure, and vitD status (as serum 25-hydroxyvitamin D, 25(OH)D). Unexpectedly, the status was significantly higher in January than in July...
January 11, 2019: Journal of the American College of Nutrition
Evgeniy Panzhinskiy, Raza Bashir, Debasis Bagchi, Sreejayan Nair
OBJECTIVE: Obesity is growing at epidemic proportions worldwide. Natural compounds curcumin and α-lipoic acid have been shown to reduce body-weight gain in both preclinical and clinical studies. This study examined the effect of a combination of curcumin and α-lipoic acid on weight gain and adiposity in high-fat-diet (HFD)-fed mice. METHODS: C57BL6 mice (7 weeks old) were randomly assigned to receive either HFD (60% fat) or a normal diet (ND, 10% fat) for a 12-week period, following which the mice receiving HFD were further assigned to supplemental curcumin (0...
January 8, 2019: Journal of the American College of Nutrition
Kinga Zięba, Magdalena Makarewicz-Wujec, Małgorzata Kozłowska-Wojciechowska
Cardiovascular diseases are the main cause of deaths in highly developed countries. Dietetic interventions that involve recommendations for consumption of products with a confirmed health-improving action are an important aspect of prevention of cardiovascular diseases. Cocoa is an alimentary product with significant cardioprotective potential due to its high content of bioactive compounds. The aim of the present study was to review the most recent literature concerning the effectiveness and mechanisms of action of compounds contained in cocoa with regard to selected cardiovascular risk factors and cardiometabolic markers...
January 8, 2019: Journal of the American College of Nutrition
Larissa Oliveira Chaves, Júlia Cristina Cardoso Carraro, Fernanda de Carvalho Vidigal, Josefina Bressan
OBJECTIVE: We evaluated whether the relationship between waist circumference (WC) and cardiometabolic risk is related to usual diet and plasma fatty acid composition. METHODS: This cross-sectional study included 226 health professionals from 20 to 59 years old. Anthropometric features, oxidative stress, inflammatory markers, and plasma fatty acid profile were assessed. Dietary intake was evaluated with a semi-quantitative food frequency questionnaire, the quality of dietary habits by Healthy Eating Index, and insulin resistance by homeostasis model assessment-insulin resistance and triglyceride-glucose index...
January 8, 2019: Journal of the American College of Nutrition
Chetan B Aware, Ravishankar R Patil, Govind D Vyavahare, Swati T Gurme, Jyoti P Jadhav
OBJECTIVE: This investigation was undertaken to optimize the effective extraction of total phenolics content (TPC), total flavonoids content (TFC), and antioxidant activity from the Mucuna macrocarpa (MM) beans. An ultrasound-assisted extraction (UAE) technique with water as an effective solvent was proposed for the response surface methodology (RSM) optimization. METHODS: A three-level, two-factor central composite design (CCD) was employed to reveal the optimal points of variables...
December 27, 2018: Journal of the American College of Nutrition
Xin Wang, De-Yi Yang, Liu-Qing Yang, Wen-Zhi Zhao, Li-Ya Cai, Han-Ping Shi
This meta-analysis aimed to summarize the association between anthocyanin consumption and the risk of colorectal cancer. All relative articles were located on online databases, including PubMed, Embase, and the Cochrane Library as of June 11, 2018. Risk ratios (RRs) or odds ratio and their 95% confidence intervals (CIs) were calculated through the STATA 12.0 software package. A total of seven studies were included in the meta-analysis. A significant inverse association was found between total anthocyanin consumption and colorectal cancer risk (RR = 0...
December 27, 2018: Journal of the American College of Nutrition
Feray Gencer, Hilal Yıldıran, Yasemin Erten
OBJECTIVE: Hemodialysis patients may be at risk for malnutrition due to catabolic effects caused by dialysis, loss of amino acids, inadequate nutrient intake, acidosis, and inflammation. Malnutrition may have negative effects on quality of life, mortality, and disease prognosis. This study was conducted to determine the relationship between anthropometric parameters, depression, and quality of life with Malnutrition Inflammation Score (MIS) on 55 patients aged between 18 and 65 years (36 males and 19 females) who have dialysis treatment for 3 days per week for at least 3 months due to end-stage renal disease...
December 27, 2018: Journal of the American College of Nutrition
Yosuke Tsuchiya, Kinjiro Hirayama, Hisashi Ueda, Eisuke Ochi
OBJECTIVE: This study investigated the effect of β-hydroxy-β-methylbutyrate (HMB) supplementation for either 2 or 4 weeks on the muscle damage after elbow flexors after eccentric contractions (ECCs). METHODS: Twenty-eight untrained men were completed the double-blind, placebo-controlled, parallel design study. The subjects were randomly assigned to the ingestion of HMB supplement for 2 weeks (HMB 2-week, n = 10), for 4 weeks (HMB 4-week, n = 10), or a placebo group (PL, n = 8)...
December 27, 2018: Journal of the American College of Nutrition
Sedat Arslan, Sibel Kadayifçilar, Gülhan Samur
OBJECTIVES: Age-related macular degeneration (AMD) is a progressive disorder among people aged ≥50 years. Some dietary factors associated with the susceptibility to AMD include dietary glycemic index and glycemic load, as well as intake of antioxidants and other nutrients, such as vitamins, minerals, and dietary fatty acids. METHODS: This case-control study was conducted between July 2015 and February 2016 on 100 case subjects with AMD and 100 healthy controls without AMD...
December 20, 2018: Journal of the American College of Nutrition
Jae Yeon Lee, Sunghee Lee
OBJECTIVE: Muscle mass plays an important role in healthy aging among elderly adults. We investigated the association between dietary patterns and appendicular skeletal muscle mass (ASM) among 3,488 adults ages 60 years or older. METHODS: The Korea National Health and Nutrition Examination Survey (KNHANES) data for 2008-2011 were analyzed. Dietary information from a food frequency questionnaire was utilized. To identify dietary patterns, factor analysis was performed...
December 20, 2018: Journal of the American College of Nutrition
Taylor C Wallace, Scott Bultman, Chris D'Adamo, Carrie R Daniel, Justine Debelius, Emily Ho, Heather Eliassen, Dawn Lemanne, Purna Mukherjee, Thomas N Seyfried, Qiang Tian, Linda T Vahdat
Cancer is a major public health problem and is the second leading cause of death in the United States and worldwide; nearly one in six deaths are attributable to cancer. Approximately 20% of all cancers diagnosed in the United States are attributable to unhealthy diet, excessive alcohol consumption, physical inactivity, and body fatness. Individual cancers are distinct disease states that are multifactorial in their causation, making them exceedingly cumbersome to study from a nutrition standpoint. Genetic influences are a major piece of the puzzle and personalized nutrition is likely to be most effective in disrupting cancer during all stages...
December 4, 2018: Journal of the American College of Nutrition
Jino Elsa Thomas, Anil K Bhat, Mahadev Rao, Vasudeva Guddattu, Sonal Sekhar M
OBJECTIVE: The purpose of the study was to assess impact of vitamin D supplements on the disease progression and overall health of osteoarthritis (OA) patients. METHODOLOGY: A cohort study was carried out for 8 months (August 2017-March 2018) in the Orthopedics Department of Kasturba Hospital, Manipal, India, a tertiary care hospital. One hundred and forty-two patients who were diagnosed with OA (grades 1-3) with low serum 25(OH)D levels (severely deficient, deficient, or insufficient) were selected for the study...
November 28, 2018: Journal of the American College of Nutrition
Laura J Lutz, Anna T Nakayama, J Philip Karl, James P McClung, Erin Gaffney-Stomberg
OBJECTIVE: Food frequency questionnaires (FFQs) estimate habitual dietary intake and require evaluation in populations of interest in order to determine accuracy. Thus, the purpose of this study was to determine agreement between circulating biomarkers and FFQ estimated dietary intake in a military population consuming all meals in a dining facility over 12 weeks. METHODS: 2014 Block FFQs were administered and fasted blood samples were drawn to assess nutritional biomarkers at the end of a 12-week training period in male (n = 141) and female (n = 125) Marine recruits undergoing initial military training...
November 6, 2018: Journal of the American College of Nutrition
Fernando Naclerio, Eneko Larumbe-Zabala, Marcos Seijo, Nadia Ashrafi, Birthe V Nielsen, Conrad P Earnest
OBJECTIVE: This study examines the long-term effects of ingesting hydrolyzed beef protein versus carbohydrate on indirect markers of immunity during 10 weeks of endurance training in master-aged triathletes (n = 16, age 35-60 years). METHODS: Participants were randomly assigned to either a hydrolyzed beef protein (PRO, n = 8) or nonprotein isoenergetic carbohydrate (CHO, n = 8) condition, which consisted of ingesting 20 g of each supplement, mixed with water, once a day immediately post workout, or before breakfast on nontraining days...
November 6, 2018: Journal of the American College of Nutrition
Lesley N Lilly, Cynthia J Heiss, Sofia F Maragoudakis, Kelli L Braden, Scott E Smith
OBJECTIVE: The purpose of this pilot study was to determine whether supplementation of a high-glycemic index breakfast meal with peanut butter attenuates the glycemic response. METHODS: Sixteen healthy adults, aged 24.1 ± 3.5 years, reported in the morning to a nutrition assessment laboratory for two days of data collection, having fasted 8 to 12 hours. On day 1 (control), fasting blood glucose (BG) was measured using glucometers, then participants consumed two slices of white bread and 250 mL apple juice (60 g carbohydrate) within 15 minutes...
November 5, 2018: Journal of the American College of Nutrition
Taylor C Wallace
Coconut oil is a mainstream edible oil that is extracted from the kernel of mature coconuts harvested from the coconut palm. The two main types of coconut oil-copra oil and virgin coconut oil-have similar fatty acid profiles; however the latter contains higher amounts of some nutrients (e.g., vitamin E) and dietary bioactive compounds (e.g., polyphenols). There is increasing popularity for coconut oil products due to perceived health effects of certain medium-chain fatty acids; however, lauric acid (C12:0), the primary fatty acid found in coconut oil, has been suggested to behave as both a medium- and long-chain fatty acid from a metabolic standpoint...
November 5, 2018: Journal of the American College of Nutrition
Malgorzata Tomaszewska, Elzbieta Sarnowska, Natalia Rusetska, Katarzyna Kowalik, Janusz Sierdzinski, Janusz A Siedlecki, Vladimir Badmaev, Sidney J Stohs, Mariola Popko
OBJECTIVES: Chronic rhinosinusitis (CRS) is a disease that represents a challenging therapeutic problem. Vitamin D and its receptors (VDR) are involved in the regulation of the immune system and may play role in CRS. Objectives of this study were to assess the relationships between the total concentration of vitamin D (25VD3) in sera, vitamin D receptor (VDR) expression, 1α-hydroxylase expression, and clinical data, including age, gender, Sino-Nasal Outcome Test (SNOT-22), computerized tomography (CT) scan, allergy status, and vitamin D supplementation in CRS patients with (CRSwNP) and without nasal polyps (CRSsNP), and in a control group...
November 2, 2018: Journal of the American College of Nutrition
Saeed Ghobadi, Zahra Hassanzadeh-Rostami, Fatemeh Mohammadian, Morteza Zare, Shiva Faghih
Hyperlipidemia is a well- known risk factor of cardiovascular disease. A healthy diet containing vegetable oils such as canola oil (CO) may help to reduce serum lipids. This study aimed to quantify the effects of CO on lipid parameters using a systematic review and meta-analysis of randomized controlled trials. PubMed, Web of Science, Scopus, ProQuest, and Embase were systematically searched until December 2017, with no time and design restrictions. Also, a manual search was performed to find extra relevant articles...
October 31, 2018: Journal of the American College of Nutrition
Junaida Astina, Suwimol Sapwarobol
Resistant maltodextrin is a non-viscous dietary fiber that is fermentable in the colon by colonic bacteria. The objective of this review is to summarize the studies of resistant maltodextrin and its effect on metabolic profile, such as blood glucose, lipid profile, and body weight. Several studies support the idea that resistant maltodextrin may improve blood glucose, insulin sensitivity, lipid profile, and obesity. However, the use of resistant maltodextrin should be limited to minimize the adverse effect on the gastrointestinal system...
October 23, 2018: Journal of the American College of Nutrition
Noriko Sugasawa, Ayako Katagi, Hirotsugu Kurobe, Taisuke Nakayama, Chika Nishio, Hiroko Takumi, Fumiharu Higashiguchi, Ken-Ichi Aihara, Michio Shimabukuro, Masataka Sata, Tetsuya Kitagawa
OBJECTIVE: Hesperidin, an abundant flavonoid in citrus fruit, and its aglycone, hesperetin, have been reported to possess various physiological activities, including antioxidant, anti-inflammatory, hypolipidemic, and antihypertensive activities. In this study, we investigated whether α-glucosyl hesperidin and water-dispersible hesperetin have protective effects on atherosclerotic progression in apolipoprotein E knockout (Apo-E KO) mice. METHODS: Ten-week-old male Apo-E KO mice were randomly assigned a regular high-fat diet, a high-fat diet with 0...
October 15, 2018: Journal of the American College of Nutrition
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