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Journal of the American College of Nutrition

Christopher R D'Adamo, James S Novick, Termeh M Feinberg, Valerie J Dawson, Larry E Miller
OBJECTIVE: Iron deficiency is the most common nutrient deficiency in the world. While deficiency can often be resolved through dietary supplementation with iron, adverse events are common and frequently preclude compliance. The objective of this study was to determine whether a food-derived dietary supplement containing a low dose of iron and nutrients that increase iron absorption could resolve iron deficiency with fewer adverse events than reported at higher doses. METHODS: A pilot clinical trial (NCT02683369) was conducted among premenopausal women with nonanemic iron deficiency that was verified by blood screening...
March 13, 2018: Journal of the American College of Nutrition
Harry G Preuss, Gilbert R Kaats, Nate Mrvichin, Debasis Bagchi, Anand Swaroop
BACKGROUND: Previous evaluations in nondiabetic subjects revealed statistically significant correlations between fasting blood glucose (FBG) levels used as an estimate of insulin resistance and many components constituting the metabolic syndrome. Similar significant correlations were not found employing chronological age as the independent variable in the same nondiabetic individuals. OBJECTIVE: The major purpose here was to replicate as well as corroborate the previous cross-sectional observations, emphasizing results obtained from data collected longitudinally...
March 13, 2018: Journal of the American College of Nutrition
Sabriye Arslan, Yasemin Akdevelioğlu
Nonclassical target organs recently defined for vitamin D, a major regulator of calcium phosphorus homeostasis and bone health, include reproductive ones. This compilation study focuses on the potential effects of vitamin D on female reproductive functions. Vitamin D receptor enzymes that metabolize vitamin D are expressed in both central and peripheral reproductive organs. Most studies suggest that vitamin D may be directly or indirectly related to gonadal functions. Vitamin D's effects on reproductive functions may be indirectly related to diseases such as polycystic ovary syndrome (PCOS), uterine leiomyomas, and endometriosis...
March 13, 2018: Journal of the American College of Nutrition
Marcel Nimni
No abstract text is available yet for this article.
March 13, 2018: Journal of the American College of Nutrition
Chou-Yueh Chang, Horng-Rong Chang, Hsing-Chun Lin, Han-Hsin Chang
Objective Vegetarian diets have been shown to increase the risk of certain nutritional deficiencies, such as iron. As a number of patients with chronic kidney disease (CKD) in Taiwan are lacto-ovo vegetarians, the aim of this study was to investigate the effects of different proportions and sources of protein in lacto-ovo vegetarian and omnivorous diets, as well as the influence of adequate dietary protein intake, on renal function and nutritional status of Taiwanese patients with stage 3 to stage 5 CKD. Methods This is a cross-sectional study...
March 13, 2018: Journal of the American College of Nutrition
Abdul-Mutala Fuseini, Mohammad Hossein Rahimi, Mehdi Mollahosseini, Mir Saeed Yekaninejad, Zhila Maghbooli, Khadijeh Mirzaei
OBJECTIVE: The role of dietary glycemic index (GI) and glycemic load (GL) in the development of obesity has been debated globally. The relationship with body shape and fat distribution was examined in this cross-sectional association study among apparently healthy Iranian adults. METHODS AND MATERIALS: A study population of 265 (126 males and 139 females) aged 18-55 years participated in this cross-sectional study from the communities of Tehran based on cluster sampling...
March 13, 2018: Journal of the American College of Nutrition
Priscila B Zanella, Camila C Àvila, Carolina G de Souza
OBJECTIVE: The objective of this study was to investigate the anthropometric and functional status in patients with pulmonary hypertension (PH) and its relationship with pulmonary circulation parameters and functional performance. METHODS: The study is cross-sectional with 34 subjects, who were evaluated in terms of anthropometric measurements, physical performance, pulmonary circulation, and regular physical activity. RESULTS: Subjects had a mean age of 47...
March 13, 2018: Journal of the American College of Nutrition
Deborah S Fetter, Rachel Erin Scherr, Jessica D Linnell, Madan Dharmar, Sara E Schaefer, Sheri Zidenberg-Cherr
OBJECTIVE: Physical activity has been shown to have a wide range of beneficial health effects, yet few youth meet the United States physical activity recommendation of 60 minutes of moderate-to-vigorous physical activity (MVPA) everyday. The objective of this study was to determine whether physical activity patterns improved in a subsample of fourth-graders participating in the multicomponent intervention, the Shaping Healthy Choices Program (SHCP). METHODS: At pre- and post-intervention assessments, youth at the control and intervention schools wore a Polar Active monitor on their nondominant wrist 24 h/d for at least 2 consecutive days...
March 13, 2018: Journal of the American College of Nutrition
Tandra R Chakraborty, Victoria Gomez, Debasis Adhikari, Sanjoy Chakraborty
OBJECTIVE: To determine the hormonal changes that occur as a result of the long-term intake of a very-high-fat diet (VHFD) that leads to simultaneous changes in the islets of Langerhans and adipocyte cell size. METHODS: Male mice were fed with a normal chow diet (ND, n = 15) and a VHFD (n = 30) for 2, 12, and 24 weeks. Body weight, food intake, caloric intake (fat [saturated and unsaturated], protein, and carbohydrate), hormone levels (leptin and insulin), and islet of Langerhans/adipocyte size were quantitatively recorded...
March 13, 2018: Journal of the American College of Nutrition
Ron Shaoul, Dalia Moati, Betty Schwartz, Yulia Pollak, Igor Sukhotnik
BACKGROUND/AIMS: Several studies have demonstrated the antimicrobial, antihelminthic, and antioxidant potential of the active ingredients of pomegranate (PMG) extracts, suggesting their preventive and curative role in several gastrointestinal disorders. In the present study, the authors evaluated the effects of oral PMG supplementation on intestinal structural changes, enterocyte proliferation, and apoptosis during methotrexate (MTX)-induced intestinal damage in a rat. METHODS: Male rats were divided into 4 experimental groups: control rats; CONTR-PMG rats were treated with oral PMG given by gavage once a day 72 hours before and 72 hours following vehicle injection; MTX rats were treated with single dose of methotrexate; and MTX-PMG rats were treated with oral PMG following injection of MTX...
March 13, 2018: Journal of the American College of Nutrition
Sedigheh Asgary, Ali Rastqar, Mahtab Keshvari
Cardiovascular disease (CVD) is now the leading cause of death globally and is a growing health concern. Lifestyle factors, including nutrition, play an important role in the etiology and treatment of CVD. Functional foods based on their basic nutritional functions can decrease the risk of many chronic diseases and have some physiological benefits. They contain physiologically active components either from plant or animal sources, marketed with the claim of their ability to reduce heart disease risk, focusing primarily on established risk factors, which are hyperlipidemia, diabetes, metabolic syndrome, obesity/overweight, elevated lipoprotein A level, small dense low-density lipoprotein cholesterol (LDL-C), and elevated inflammatory marker levels...
March 12, 2018: Journal of the American College of Nutrition
Vajihe Izadi, Fahimeh Haghighatdoost, Parisa Moosavian, Leila Azadbakht
BACKGROUND: There are no investigations regarding the effects of consuming low-energy-dense diets rich in multiple functional foods on weight-loss maintenance, inflammatory markers, and cardiovascular disease (CVD) risk factors simultaneously. METHOD: This randomized controlled trial design was conducted on 90 men and women who were under a previous weight loss diet. Three months of intervention with recruitment at Allzahra Hospital, Isfahan, Iran, was done. Intervention was conducted following achieving 7-11 kg weight loss...
March 12, 2018: Journal of the American College of Nutrition
Taylor C Wallace
In 2030, one in five Americans will be older than 65 years, and with that an increase in the number of individuals who experience loss in cognitive capacity is to be expected. At the same time, nutrition within the first 1000 days postconception has been suggested to strongly influence cognitive outcomes across the life-span in humans. Eggs are a primary source of both choline and the xanthophyll carotenoid lutein in the western diet, and both have been suggested to influence cognitive function in humans. This comprehensive review critically examines the effects of eggs, choline, and lutein on cognition across the life-span...
February 16, 2018: Journal of the American College of Nutrition
Quadri Kunle Alabi, Rufus Ojo Akomolafe, Olaoluwa Sesan Olukiran, Aliyat Olajumoke Nafiu, Modinat Adebukola Adefisayo, Olurotimi Isaac Owotomo, Joseph Gbenga Omole, Kehinde Peace Olamilosoye
OBJECTIVES: Cisplatin (CIS) is an effective antitumor drug. However, its clinical use is limited due to nephrotoxicity. l-Carnitine and vitamin C are both natural antioxidant that can be obtained from diets. This study investigated the effects of l-carnitine and/or vitamin C in rats against cisplatin-induced nephrotoxicity. METHODS: Twenty-five male Wistar rats were divided into 5 groups of 5 rats each. Group 1, normal control. Group 2, positive control, received cisplatin (10 mg/kg/day intraperitoneally [i...
February 9, 2018: Journal of the American College of Nutrition
Sayali S Deshpande-Joshi, Shobha Rao
OBJECTIVE: Assessing risk of hypertension in relation to decadal changes in anthropometry among cohort of young rural Indian men. METHODS: Subjects (n = 140) were measured in 2005 and 2015 for blood pressure, body mass index (BMI), body fat (BF), waist circumference (WC), waist-to-hip ratio (WHR), and additionally for visceral fat (VF) at follow-up. RESULTS: Decadal changes showed significant (p < 0.001) increase in mean anthropometric measures and in prevalence of overall obesity (BMI ≥25 kg/m2) from 3...
February 9, 2018: Journal of the American College of Nutrition
Lílian L Lopes, Daniela Mayumi U P Rocha, Alessandra da Silva, Maria do Carmo G Peluzio, Josefina Bressan, Helen Hermana M Hermsdorff
PURPOSE: We evaluated postprandial response of the lipid metabolism markers after the intake of a high-saturated fat (HSM) or high-monounsaturated fat meal (HMM). METHODS: A randomized, controlled and acute intervention study included 63 women (age 26.9 ± 6.1 years): 35 normal weight (NW) and 28 overweight (OW) (total body fat [TBF] 24.7 ± 3.9% and 36.6 ± 3.9%, respectively). After 12 hours of fasting, each subject was given one of the two test meals standardized, including 2 muffins and water (HSM, 42...
February 9, 2018: Journal of the American College of Nutrition
Sedigheh Asgary, Leila Salehizadeh, Mahtab Keshvari, Marzieh Taheri, Nicholas D Spence, Maryam S Farvid, Mahmoud Rafieian-Kopaei, Nizal Sarrafzadegan
OBJECTIVE: Alternative medicine and herbal drugs have been taken into account for managing cardiovascular risk factors. Sumac (Rhus coriaria L.) is rich in biologically active ingredients known to improve cardiovascular health. We investigated the effect of sumac on systolic (SBP) and diastolic (DBP) blood pressure, flow-mediated dilation (FMD), body mass index (BMI), and serum concentrations of lipids and fasting blood sugar (FBS) in participants with hyperlipidemia in a triple-blind randomized placebo- controlled crossover trial...
February 9, 2018: Journal of the American College of Nutrition
Decker Weiss, Debra K Brunk, Dennis A Goodman
OBJECTIVE: Suboptimal magnesium status is likely widespread in the United States and increasing evidence links it to many chronic diseases. Therapeutically addressing magnesium status can be challenging, as higher supplementation often leads to bowel intolerance. This study evaluated the absorption, cellular uptake, and clinical effectiveness of a timed-release formulation containing dimagnesium malate with vitamins B6, B12, and folate (MagSRT™) in a standard clinical population. METHODS: A standard clinical population of 91 adults participated in a placebo-controlled study carried out at two clinics; 53 individuals received MagSRT™, containing 500 mg dimagnesium malate and vitamins B6, B12, and folate, while the remaining individuals received a placebo...
February 9, 2018: Journal of the American College of Nutrition
Elisavet Parlapani, Charalampos Agakidis, Thomais Karagiozoglou-Lampoudi
The improved survival of preterm infants has led to increased interest regarding their health as adults. In the context of metabolic programming, the connection between perinatal and early postnatal nutrition and growth with health in later life has brought to the fore the role of catch-up growth during the first months of preterm infants' lives and its association with body fat and obesity in childhood or puberty. A state-of-the art review was conducted in order to assess the way catch-up is evaluated, in terms of timing and rate...
February 9, 2018: Journal of the American College of Nutrition
Stavros Papadopoulos, Konstantina Dipla, Areti Triantafyllou, Michalis G Nikolaidis, Antonios Kyparos, Panagiota Touplikioti, Ioannis S Vrabas, Andreas Zafeiridis
OBJECTIVE: To examine the effects of beetroot juice (BRJ) on (i) in vivo skeletal muscle O2 consumption (mVO2) and microvascular reactivity at rest and (ii) muscle performance, muscle oxygenation, and mVO2 during sustained isometric handgrip exercise (IHG). METHODS: Sixteen young males consumed, randomly, a nitrate-rich (8.1 mmol BRJnitrate) or nitrate-depleted (BRJplacebo) BRJ. After 2.5 hours, they performed an occlusion-reperfusion maneuver at rest, a 3-minute sustained IHG, and a sustained IHG to exhaustion with arterial occlusion...
February 9, 2018: Journal of the American College of Nutrition
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