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Magnetic Resonance Imaging

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https://www.readbyqxmd.com/read/28095303/gd-dtpa-induced-dynamic-metabonomic-changes-in-rat-biofluids
#1
Chuanling Wan, Youyang Zhan, Rong Xue, Yijie Wu, Xiaojing Li, Fengkui Pei
OBJECTIVES: The purposes of this study were (1) to detect the dynamic metabonomic changes induced by gadopentetate dimeglumine (Gd-DTPA) and (2) to investigate the potential metabolic disturbances associated with the pathogenesis of nephrogenic systemic fibrosis (NSF) at the early stage. METHODS: A nuclear magnetic resonance (NMR)-based metabolomics approach was used to investigate the urinary and serum metabolic changes induced by a single tail vein injection of Gd-DTPA (dosed at 2 and 5mmol/kg body weight) in rats...
January 14, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28095302/internal-evaluation-of-impregnation-treatment-of-waterlogged-wood-relation-between-concentration-of-internal-materials-and-relaxation-time-using-magnetic-resonance-imaging
#2
Yuki Kanazawa, Tetsuya Yamada, Aki Kido, Koji Fujimoto, Kyoko Takakura, Hiroaki Hayashi, Yasutaka Fushimi, Satoshi Kozawa, Koji Koizumi, Makiko Okuni, Naomi Ueda, Kaori Togashi
The purpose of this study is to clarify the degree of impregnation resulting from treatment of internal waterlogged wood samples using MRI. On a 1.5T MR scanner, T1 and T2 measurements were performed using inversion recovery and spin-echo sequences, respectively. The samples were cut waterlogged pieces of wood treated with various impregnation techniques which were divided into different concentrations of trehalose (C12H22O11) and polyethylene glycol (PEG; HO-(C2H4O)n-H) solutions. Then these samples underwent impregnation treatment every two weeks...
January 14, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28093270/cardiac-magnetic-resonance-tissue-tracking-in-right-ventricle-feasibility-and-normal-values
#3
Vien T Truong, Komal S Safdar, Dinesh K Kalra, Xuexin Gao, Stephanie Ambach, Michael D Taylor, Ryan Moore, Robin J Taylor, Joshua Germann, Olga Toro-Salazar, John L Jefferies, Cheryl Bartone, Subha V Raman, Tam Ngo, Wojciech Mazur
PURPOSE: To investigate right ventricular (RV) strain in patients without identified cardiac pathology using cardiac magnetic resonance tissue tracking (CMR TT). METHODS: A total of 50 consecutive patients with no identified cardiac pathology were analyzed. RV longitudinal and circumferential strain was assessed by CMR TT. The age range was 4-81years with a median of 32years (interquartile range, 15 to 56years). RESULTS: Analysis time per patient was <5min...
January 13, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28089940/assessing-the-effect-of-football-play-on-knee-articular-cartilage-using-delayed-gadolinium-enhanced-mri-of-cartilage-dgemric
#4
Wenbo Wei, Becky Lambach, Guang Jia, David Flanigan, Ajit M W Chaudhari, Lai Wei, Alan Rogers, Jason Payne, Robert A Siston, Michael V Knopp
The prevalence of cartilage lesions is much higher in football athletes than in the general population. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) has been shown to quantify regional variations of glycosaminoglycan (GAG) concentrations which is an indicator of early cartilage degeneration. The goal of this study is to determine whether dGEMRIC can be used to assess the influence in cartilage GAG concentration due to college level football play. Thirteen collegiate football players with one to four years of collegiate football play experience were recruited and both knee joints were scanned using a dedicated 8-channel phased array knee coil on a 3T MRI system...
January 12, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28089939/chemical-exchange-saturation-transfer-imaging-advances-and-applications-by-michael-t-mcmahon-assaf-a-gild-jeff-w-m-bulte-and-peter-c-m-van-zijl-publisher-pan-stanford-publishing-pte-ltd-singapore
#5
https://www.readbyqxmd.com/read/28089938/3d-printed-rf-probeheads-for-low-cost-high-throughput-nmr
#6
R Adam Horch, John C Gore
3D printing has been exploited as a means to fabricate complete NMR probeheads containing arrays of miniature RF circuits for high-throughput solution-state NMR spectroscopy and potentially other purposes. 3D-printed NMR circuits of millimeter scale were constructed consisting of RF coils, variable tuning/matching capacitors, and liquid NMR sample cavities. Channels and cavities capable of being addressed using microfluidics are included in the probehead structure, providing a means for hydraulically-controlled RF tuning/matching and liquid NMR sample loading/unloading...
January 12, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28089499/the-stability-of-gadolinium-based-contrast-agents-in-human-serum-a-reanalysis-of-literature-data-and-association-with-clinical-outcomes
#7
John P Prybylski, Richard C Semelka, Michael Jay
PURPOSE: To reanalyze literature data of gadolinium (Gd)-based contrast agents (GBCAs) in plasma with a kinetic model of dissociation to provide a comprehensive assessment of equilibrium conditions for linear GBCAs. METHODS: Data for the release of Gd from GBCAs in human serum was extracted from a previous report in the literature and fit to a kinetic dissociation/association model. The conditional stabilities (logKcond) and percent intact over time were calculated using the model rate constants...
January 9, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28077268/development-of-high-resolution-3d-hyperpolarized-carbon-13-mr-molecular-imaging-techniques
#8
Eugene Milshteyn, Cornelius von Morze, Galen D Reed, Hong Shang, Peter J Shin, Zihan Zhu, Hsin-Yu Chen, Robert Bok, Andrei Goga, John Kurhanewicz, Peder E Z Larson, Daniel B Vigneron
The goal of this project was to develop and apply techniques for T2 mapping and 3D high resolution (1.5 mm isotropic; 0.003 cm(3)) (13)C imaging of hyperpolarized (HP) probes [1-(13)C]lactate, [1-(13)C]pyruvate, [2-(13)C]pyruvate, and [(13)C,(15)N2]urea in vivo. A specialized 2D bSSFP sequence was implemented on a clinical 3T scanner and used to obtain the first high resolution T2 maps of these different hyperpolarized compounds in both rats and tumor-bearing mice. These maps were first used to optimize timings for highest SNR for single time-point 3D bSSFP acquisitions with a 1...
January 7, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28077267/rapid-whole-brain-myelin-water-content-mapping-without-an-external-water-standard-at-1-5t
#9
Thanh D Nguyen, Pascal Spincemaille, Susan A Gauthier, Yi Wang
The objective of this study is to develop rapid whole brain mapping of myelin water content (MWC) at 1.5T. The Fast Acquisition with Spiral Trajectory and T2prep (FAST-T2) pulse sequence originally developed for myelin water fraction (MWF) mapping was modified to obtain fast mapping of T1 and receiver coil sensitivity needed for MWC computation. The accuracy of the proposed T1 mapping was evaluated by comparing with the standard IR-FSE method. Numerical simulations were performed to assess the accuracy and reliability of the proposed MWC mapping...
January 7, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28069416/abnormal-lipid-metabolism-in-skeletal-muscle-tissue-of-patients-with-muscular-dystrophy-in-vitro-high-resolution-nmr-spectroscopy-based-observation-in-early-phase-of-the-disease
#10
Niraj Kumar Srivastava, Ramakant Yadav, Somnath Mukherjee, Lily Pal, Neeraj Sinha
PURPOSE: Qualitative (assignment of lipid components) and quantitative (quantification of lipid components) analysis of lipid components were performed in skeletal muscle tissue of patients with muscular dystrophy in early phase of the disease as compared to control/normal subjects. METHODS: Proton nuclear magnetic resonance (NMR) spectroscopy based experiment was performed on the lipid extract of skeletal muscle tissue of patients with muscular dystrophy in early phase of the disease and normal individuals for the analysis of lipid components [triglycerides, phospholipids, total cholesterol and unsaturated fatty acids (arachidonic, linolenic and linoleic acid)]...
January 6, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28065695/perfusion-of-the-uterine-junctional-zone-in-nulliparous-and-primiparous-women-assessed-by-dce-mri-as-a-function-of-menstrual-cycle-and-hormonal-contraception
#11
L J Meylaerts, L Wijnen, M Bazot, M Grieten, W Ombelet, M Vandersteen
PURPOSE: To evaluate the perfusion parameters of inner and outer myometrium in healthy nulliparous and primiparous women who are and who are not currently using hormonal contraceptives by means of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). MATERIAL AND METHODS: We performed pelvic 1.5T DCE-MRI on 98 women: 18 nulliparous non-users, 30 nulliparous users, 12 primiparous non-users and 38 primiparous users of hormonal contraception (mean age respectively 26...
January 6, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28065694/real-time-cardiac-magnetic-resonance-cine-imaging-with-sparse-sampling-and-iterative-reconstruction-for-left-ventricular-measures-comparison-with-gold-standard-segmented-steady-state-free-precession
#12
Gabriel C Camargo, Fernanda Erthal, Leticia Sabioni, Filipe Penna, Ralph Strecker, Michaela Schmidt, Michael O Zenge, Ronaldo de S L Lima, Ilan Gottlieb
BACKGROUND: Segmented cine imaging with a steady-state free-precession sequence (Cine-SSFP) is currently the gold standard technique for measuring ventricular volumes and mass, but due to multi breath-hold (BH) requirements, it is prone to misalignment of consecutive slices, time consuming and dependent on respiratory capacity. Real-time cine avoids those limitations, but poor spatial and temporal resolution of conventional sequences has prevented its routine application. We sought to examine the accuracy and feasibility of a newly developed real-time sequence with aggressive under-sampling of k-space using sparse sampling and iterative reconstruction (Cine-RT)...
January 6, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28063997/colorectal-carcinoma-ex-vivo-evaluation-using-3-t-high-spatial-resolution-quantitative-t2-mapping-and-its-correlation-with-histopathologic-findings
#13
Ichiro Yamada, Norio Yoshino, Keigo Hikishima, Naoyuki Miyasaka, Shinichi Yamauchi, Hiroyuki Uetake, Masamichi Yasuno, Yukihisa Saida, Ukihide Tateishi, Daisuke Kobayashi, Yoshinobu Eishi
PURPOSE: In this study, we aimed to evaluate the feasibility of determining the mural invasion depths of colorectal carcinomas using high-spatial-resolution (HSR) quantitative T2 mapping on a 3-T magnetic resonance (MR) scanner. MATERIALS AND METHODS: Twenty colorectal specimens containing adenocarcinomas were imaged on a 3-T MR system equipped with a 4-channel phased-array surface coil. HSR quantitative T2 maps were acquired using a spin-echo sequence with a repetition time/echo time of 7650/22...
January 4, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28062263/the-natural-history-of-streptozotocin-stimulated-non-alcoholic-steatohepatitis-mice-followed-by-gd-eob-dtpa-enhanced-mri-comparison-with-simple-steatosis-mice
#14
Hiroyuki Akai, Shigeru Kiryu, Yasunori Ohta, Koichiro Yasaka, Yoshiyasu Nakano, Yusuke Inoue, Kuni Ohtomo
PURPOSE: To clarify the development of HCC, temporal change of steatosis and Gd-EOB-DTPA enhancement of non-alcoholic steatohepatitis (NASH) model mice by magnetic resonance imaging (MRI). MATERIALS AND METHODS: All animal experiments were approved by the institution's Animal Research Committee. MRI was performed on six NASH and six simple steatosis (SS) model mice every 2weeks from the ages of 8weeks to 16weeks. The sequential changes in the number and size of the focal liver lesions detected on Gd-EOB-DTPA-enhanced MRI were evaluated...
January 3, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28057481/bayesian-mri-denoising-in-complex-domain
#15
Fabio Baselice, Giampaolo Ferraioli, Vito Pascazio, Antonietta Sorriso
In recent years, several efforts have been done for producing Magnetic Resonance Image scanner with higher magnetic field strength mainly for increasing the Signal to Noise Ratio and the Contrast to Noise Ratio of the acquired images. However, denoising methodologies still play an important role for achieving images neatness. Several denoising algorithms have been presented in literature. Some of them exploit the statistical characteristics of the involved noise, some others project the image in a transformed domain, some others look for geometrical properties of the image...
January 3, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28038965/inversion-recovery-ultrashort-echo-time-magnetic-resonance-imaging-a-method-for-simultaneous-direct-detection-of-myelin-and-high-signal-demonstration-of-iron-deposition-in-the-brain-a-feasibility-study
#16
Vipul R Sheth, Shujuan Fan, Qun He, Yajun Ma, Jacopo Annese, Robert Switzer, Jody Corey-Bloom, Graeme M Bydder, Jiang Du
Multiple sclerosis (MS) causes demyelinating lesions in the white matter and increased iron deposition in the subcortical gray matter. Myelin protons have an extremely short T2* (<1ms) and are not directly detected with conventional clinical magnetic resonance (MR) imaging sequences. Iron deposition also reduces T2*, leading to reduced signal on clinical sequences. In this study we tested the hypothesis that the inversion recovery ultrashort echo time (IR-UTE) pulse sequence can directly and simultaneously image myelin and iron deposition using a clinical 3T scanner...
December 28, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28038964/intravoxel-incoherent-motion-and-diffusion-tensor-imaging-of-early-renal-fibrosis-induced-in-a-murine-model-of-streptozotocin-induced-diabetes
#17
Y Y Yan, S Hartono, T Hennedige, T S Koh, C M Chan, L Zhou, H Rumpel, L Martarello, J B Khoo, D M Koh, K H Chuang, K H Tony Lim, Y Y Dan, C H Thng
INTRODUCTION: To assess if parameters in intravoxel incoherent motion (IVIM) and diffusion tensor imaging (DTI) can be used to evaluate early renal fibrosis in a mouse model of diabetic nephropathy. MATERIALS & METHODS: In a population of 38 male CD1 mice (8weeks old, 20-30g), streptozotocin induced diabetes was created in 20 mice via a single intraperitoneal injection of streptozotocin at 150mg/kg, while 18 mice served as control group. IVIM parameters were acquired at 0, 12 and 24weeks after injection of streptozotocin using a range of b values from 0 to 1200s/mm(2)...
December 28, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28034637/image-based-gradient-non-linearity-characterization-to-determine-higher-order-spherical-harmonic-coefficients-for-improved-spatial-position-accuracy-in-magnetic-resonance-imaging
#18
Paul T Weavers, Shengzhen Tao, Joshua D Trzasko, Yunhong Shu, Erik J Tryggestad, Jeffrey L Gunter, Kiaran P McGee, Daniel V Litwiller, Ken-Pin Hwang, Matt A Bernstein
PURPOSE: Spatial position accuracy in magnetic resonance imaging (MRI) is an important concern for a variety of applications, including radiation therapy planning, surgical planning, and longitudinal studies of morphologic changes to study neurodegenerative diseases. Spatial accuracy is strongly influenced by gradient linearity. This work presents a method for characterizing the gradient non-linearity fields on a per-system basis, and using this information to provide improved and higher-order (9th vs...
December 27, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28034638/free-breathing-whole-heart-3d-cine-mri-with-self-gated-cartesian-trajectory
#19
M Usman, B Ruijsink, M S Nazir, G Cruz, C Prieto
PURPOSE: To present a method that uses a novel free-running self-gated acquisition to achieve isotropic resolution in whole heart 3D Cartesian cardiac CINE MRI. MATERIAL AND METHODS: 3D cardiac CINE MRI using navigator gating results in long acquisition times. Recently, several frameworks based on self-gated non-Cartesian trajectories have been proposed to accelerate this acquisition. However, non-Cartesian reconstructions are computationally expensive due to gridding, particularly in 3D...
December 26, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28027908/quantification-of-intervertebral-displacement-with-a-novel-mri-based-modeling-technique-assessing-measurement-bias-and-reliability-with-a-porcine-spine-model
#20
Niladri K Mahato, Stephane Montuelle, Craig Goubeaux, John Cotton, Susan Williams, James Thomas, Brian C Clark
The purpose of this study was to develop a novel magnetic resonance imaging (MRI)-based modeling technique for measuring intervertebral displacements. Here, we present the measurement bias and reliability of the developmental work using a porcine spine model. Porcine lumbar vertebral segments were fitted in a custom-built apparatus placed within an externally calibrated imaging volume of an open-MRI scanner. The apparatus allowed movement of the vertebrae through pre-assigned magnitudes of sagittal and coronal translation and rotation...
December 24, 2016: Magnetic Resonance Imaging
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