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Archives of Gerontology and Geriatrics

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https://www.readbyqxmd.com/read/27918964/sarcopenia-in-older-mice-is-characterized-by-a-decreased-anabolic-response-to-a-protein-meal
#1
Miriam van Dijk, Jolanda Nagel, Francina J Dijk, Jerôme Salles, Sjors Verlaan, Stephane Walrand, Klaske van Norren, Yvette Luiking
Ageing is associated with sarcopenia, a progressive decline of skeletal muscle mass, muscle quality and muscle function. Reduced sensitivity of older muscles to respond to anabolic stimuli, i.e. anabolic resistance, is part of the underlying mechanisms. Although, muscle parameters have been studied in mice of various ages/strains; the aim was to study if mice display similar deteriorating processes as human ageing. Therefore, 10,16,21 and 25 months-old C57BL6/6J male mice were studied to measure parameters of sarcopenia and factors contributing to its pathophysiology, with the aim of characterizing sarcopenia in old mice...
November 27, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27923177/the-effect-of-exergaming-on-knee-proprioception-in-older-men-a-randomized-controlled-trial
#2
Hassan Sadeghi, Mohammad Nazrul Hakim, Tengku Aizan Hamid, Saidon Bin Amri, Mohsen Razeghi, Mohammadreza Farazdaghi, Elham Shakoor
BACKGROUND: Proprioception is the ability to sense the body position, muscle sense, joint stability and posture. As balance decreases during the process of aging, knee proprioception has a critical role in body balance and daily activities. Exergaming has shown to be a potentially effective and more enjoyable form of exercise delivery. OBJECTIVE: The purpose of this study was to determine the effect of an 8-week Xbox Kinect exercise program on knee proprioception in healthy older adults...
November 23, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27914296/gender-differences-in-primary-home-caregivers-of-older-relatives-in-a-mediterranean-environment-a-cross-sectional-study
#3
Rafael Del-Pino-Casado, María Del Mar Pastor-Bravo, Pedro A Palomino-Moral, Antonio Frías-Osuna
A cross-sectional study was developed in Spain to analyse gender differences in intensity of care, care recipient needs and subjective burden, as well as the moderating effects of kinship on the relationship between gender and subjective burden. A probabilistic sample of 200 primary caregivers (100 male and 100 female) of older relatives was interviewed by expert nurses. Socio-demographic data and several scales regarding objective and subjective burden were used to collect data. Descriptive statistics, Student's t-test, ANOVA and multiple linear regression were used to analyse the data...
November 21, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27912157/factors-related-to-satisfaction-with-long-term-care-services-among-low-income-korean-elderly-adults-a-national-cross-sectional-survey
#4
Chanyeong Kwak, Eunhee Lee, Hyunjung Kim
BACKGROUND: With the growing demand for long-term care (LTC) services, it is increasingly important to explore experience with care. This study examined care satisfaction in a nursing home and at home among low-income elders in South Korea. METHODS: This cross-sectional study was conducted with 246 elderly recipients of welfare benefits using a proportional stratified sampling method. Two self-reported versions of a questionnaire developed for users of nursing home care and homecare were used...
November 21, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27889590/perceived-and-objective-entrance-related-environmental-barriers-and-daily-out-of-home-mobility-in-community-dwelling-older-people
#5
Erja Portegijs, Merja Rantakokko, Anne Viljanen, Taina Rantanen, Susanne Iwarsson
PURPOSE: We studied whether entrance-related environmental barriers, perceived and objectively recorded, were associated with moving out-of-home daily in older people with and without limitations in lower extremity performance. METHODS: Cross-sectional analyses of the "Life-space mobility in old age" cohort including 848 community-dwelling 75-90-year-old of central Finland. Participants reported their frequency of moving out-of-home (daily vs. 0-6 times/week) and perceived entrance-related environmental barriers (yes/no)...
November 19, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27888735/leisure-participation-and-subjective-well-being-exploring-gender-differences-among-elderly-in-shanghai-china
#6
Wei Zhang, Qiushi Feng, Joy Lacanienta, Zhihong Zhen
OBJECTIVES: To explore the association between leisure participation and subjective well-being and the role gender in this issue among elderly Chinese in Shanghai, China. METHODS: Principal components analysis and logistic regressions are used to analyze the cross-sectional data of the 2013 Shanghai Elderly Life and Opinion Survey that contains 2884 respondents (60+ with a mean age of 72.6) recruited from a multistage cluster sampling design. Subjective well-being is measured by happiness and life satisfaction, and leisure participation is examined by the type and diversity of leisure activities...
November 19, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27914295/sarcopenia-and-post-hospital-outcomes-in-older-adults-a-longitudinal-study
#7
Mario Ulises Pérez-Zepeda, Aldo Sgaravatti, Elsa Dent
INTRODUCTION: Sarcopenia poses a significant problem for older adults, yet very little is known about this medical condition in the hospital setting. The aims of this hospital-based study were to determine: (i) the prevalence of sarcopenia; (ii) factors associated with sarcopenia; and (iii) the association of sarcopenia with adverse clinical outcomes post-hospitalisation. METHODS: This is a longitudinal analysis of consecutive patients aged ≥70 years admitted to a Geriatric Management and Evaluation Unit (GEMU) ward...
November 17, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27889589/higher-morale-is-associated-with-lower-risk-of-depressive-disorders-five-years-later-among-very-old-people
#8
Johan Niklasson, Marina Näsman, Fredrica Nyqvist, Mia Conradsson, Birgitta Olofsson, Hugo Lövheim, Yngve Gustafson
The aim of this study was to investigate whether higher morale, i.e. future-oriented optimism, at baseline was associated with lower risk of depressive disorders five years later among very old people.Methods The Umeå85+/GErontological Regional Database, a population-based study with a longitudinal design, recruited participants in Sweden and Finland aged 85, 90 and ≥95 years. The sample in the present study included 647 individuals (89.1±4.4 years (Mean±SD), range 85-103). After five years, 216 were alive and agreed to a follow-up (92...
November 17, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27888736/activity-engagement-and-physical-function-in-old-age-sample
#9
Krupa N Shah, Feng V Lin, Fang Yu, James M McMahon
OBJECTIVES: To describe the patterns of engagement in mental, physical, and social activity (MA, PA, and SA) and to examine the relationship between combined activity engagement and physical function among community-dwelling older adults. DESIGN: Cross-sectional correlational study. SETTING: Multiple communities. PARTICIPANTS: A total of 466 individuals aged 55 years or older. MEASUREMENTS: Physical function was assessed using grip strength and gait speed...
November 17, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27886565/investigating-the-relationship-between-reduced-self-awareness-of-falls-risk-rehabilitation-engagement-and-falls-in-older-adults
#10
Tijana Mihaljcic, Terry P Haines, Jennie L Ponsford, Renerus J Stolwyk
The present study aimed to investigate whether self-awareness of falls risk is associated with rehabilitation engagement, motivation for rehabilitation, and number of falls after hospital discharge. The sample comprised 91 older adults (Mage=77.97, SD=8.04) undergoing inpatient rehabilitation. The Self-Awareness of Falls Risk Measure (SAFRM) was used to measure different aspects of self-awareness. The treating physiotherapist and occupational therapist rated the patient's engagement in rehabilitation and the patient reported his/her motivation for treatment...
November 16, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27889591/adverse-events-and-treatment-discontinuations-of-antimuscarinics-for-the-treatment-of-overactive-bladder-in-older-adults-a-systematic-review-and-meta-analysis
#11
REVIEW
Scott Martin Vouri, Clark D Kebodeaux, Paul M Stranges, Besu F Teshome
INTRODUCTION: Antimuscarinics should be used with caution in older adults with overactive bladder (OAB) due to anticholinergic adverse events (AEs). Systematic reviews and meta-analyses (SRMAs) have analyzed safety-related outcomes but have not specified risk in the elderly, the population at highest risk for AEs. The aim of this review is to explore and evaluate AEs and treatment discontinuations in adults 65 or older taking antimuscarinics for OAB. METHODS: Keywords were searched in MEDLINE, EMBASE, SCOPUS, and Cochrane Central Register for Controlled Trials...
November 14, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27875713/prognostic-value-of-degree-and-types-of-anaemia-on-clinical-outcomes-for-hospitalised-older-patients
#12
Emma Riva, Riccardo Colombo, Guido Moreo, Sara Mandelli, Carlotta Franchi, Luca Pasina, Mauro Tettamanti, Ugo Lucca, Pier Mannuccio Mannucci, Alessandro Nobili
STUDY OBJECTIVE: This study investigated in a large sample of in-patients the impact of mild-moderate-severe anaemia on clinical outcomes such as in-hospital mortality, re-admission, and death within three months after discharge. METHODS: A prospective multicentre observational study, involving older people admitted to 87 internal medicine and geriatric wards, was done in Italy between 2010 and 2012. The main clinical/laboratory data were obtained on admission and discharge...
November 14, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27866086/the-role-of-postural-instability-gait-difficulty-and-fear-of-falling-in-predicting-falls-in-non-demented-older-adults
#13
Gilles Allali, Emmeline I Ayers, Roee Holtzer, Joe Verghese
INTRODUCTION: Postural instability/gait difficulty (PIGD) and fear of falling (FoF) frequently co-exist, but their individual predictive values for falls have not been compared in aging. This study aims to determine both independent and combined effect of PIGD and FoF to falls in older adults without dementia. METHODS: PIGD and other extrapyramidal signs were systematically assessed in 449 community-dwelling participants without Parkinson's disease (76.48±6.61 ys; 56...
November 13, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27886564/c-reactive-protein-is-related-to-future-cognitive-impairment-and-decline-in-elderly-individuals-with-cardiovascular-disease
#14
Galit Weinstein, Miriam Lutski, Uri Goldbourt, David Tanne
AIMS: To explore the association of C-reactive protein (CRP) plasma levels with subsequent cognitive performance and decline among elderly individuals with pre-existing cardiovascular disease (CVD), and to assess the role of cerebrovascular indices in this relationship. METHODS: CRP levels were measured in a subgroup of individuals with chronic CVD, who previously participated in a secondary prevention trial. Cognitive performance was evaluated 14.7±1.9 and 19...
November 9, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27866087/a-predictive-model-for-estimating-regional-skeletal-muscle-size-by-two-point-dixon-magnetic-resonance-imaging-in-healthy-koreans
#15
Cheol-Min Kim, Chang-Hyung Lee, Young A Choi, Byoung-Chul Kim, Duk-Young Jung, Myung-Jun Shin
This study was undertaken to develop and cross-validate reference and individual predictive models for estimating functional thigh muscle cross-sectional area (TCSA) by 2-point Dixon magnetic resonance imaging (MRI). TCSAs of dominant sides at the mid-thigh level were measured by 2-point Dixon MRI ((MRI)TCSA). Functional (MRI)TCSA were compared with the predictive models in a sample of 92 younger (20-40 years; 28.55±4.87; n=50) and older (>65years; 71.22±4.82; n=42) Koreans. Lean body masses were measured by dual energy X-ray absorptiometry ((DXA)LBM), and thigh isokinetic muscle strengths, extension peak torque at 60°/sec, were measured using a Biodex(®) dynamometer ((Biodex)EPT)...
November 6, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27855319/caring-for-disabled-older-adults-with-musculoskeletal-conditions-a-transactional-model-of-caregiver-burden-coping-strategies-and-depressive-symptoms
#16
Nan Lu, Jinyu Liu, Fei Wang, Vivian W Q Lou
OBJECTIVES: This study investigated the mediating role of coping strategies in the relationship between caregiver burden and depressive symptoms among family caregivers caring for disabled older adults with musculoskeletal (MSK) conditions. METHODS: The cross-sectional data were from a quota sampling of 494 pairs of disabled older adults and their primary family caregivers in Shanghai, China. The disabled older adults had MSK conditions and limitations in activities of daily living...
November 4, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27912156/health-benefits-of-aerobic-training-programs-in-adults-aged-70-and-over-a-systematic-review
#17
REVIEW
Walid Bouaziz, Thomas Vogel, Elise Schmitt, Georges Kaltenbach, Bernard Geny, Pierre Olivier Lang
Aging is intrinsically associated with a progressive decline in muscle strength and mass, and aerobic capacity. This contributes to reduced mobility and impaired quality of life (QoL) among seniors. Regular physical activity, and more particularly aerobic training (AT), has demonstrated benefits on adults' health. The aim of this review was to assess the current level of evidence regarding the health benefits of AT in the population aged 70 years and over. A comprehensive, systematic database search for manuscripts was performed...
October 31, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27837709/the-effect-of-comprehensive-geriatric-assessment-on-anticholinergic-exposure-assessed-by-four-ranked-anticholinergic-lists
#18
Pasi Lampela, Heidi Taipale, Piia Lavikainen, Sirpa Hartikainen
BACKGROUND: Older people often use multiple drugs, and some of them have anticholinergic activity. Anticholinergic drugs may cause adverse reactions, and therefore their use should be limited. To identify anticholinergic load, several ranked lists with different drugs and scoring systems have been developed and used widely in research. We investigated, if a comprehensive geriatric assessment (CGA) decreased the anticholinergic drug score in a 4-year period. We used four different anticholinergic ranked lists to determine the anticholinergic score and to describe how the results differ depending on the list used...
January 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27835771/self-perception-of-uselessness-and-mortality-among-older-adults-in-china
#19
Danan Gu, Matthew E Dupre, Li Qiu
BACKGROUND: Negative self-perceptions of aging among older adults have been associated with higher mortality in developed countries. However, it is unclear whether an association exists in developing countries where living to older age is more selective. DESIGN AND METHODS: Using five waves of data (2000, 2002, 2005, 2008, and 2011) from a national survey of adults aged 65 and older in China (n=30,948), this study investigates how self-perceived feelings of uselessness are associated with subsequent mortality...
January 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27835770/the-effects-of-eyeball-exercise-on-balance-ability-and-falls-efficacy-of-the-elderly-who-have-experienced-a-fall-a-single-blind-randomized-controlled-trial
#20
Jin-Hyuck Park
PURPOSE: The purpose of this study was to investigate the effects of eyeball exercise on balance and fall efficacy of the elderly who have experienced a fall. MATERIAL AND METHODS: Subjects were randomly assigned to the eyeball exercise group (n=30) or functional exercise group (n=31). All subjects received 30 sessions for 10 weeks. To identify the effects on balance, static and dynamic balance were measured using the center of pressure (CoP) measurement equipment and Timed Up and Go Test (TUGT) respectively...
January 2017: Archives of Gerontology and Geriatrics
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