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Acta Otorhinolaryngologica Italica

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https://www.readbyqxmd.com/read/28177337/free-flap-loss-caused-by-heparin-induced-thrombocytopenia-and-thrombosis-hitt-a-case-report-and-literature-review
#1
E Segna, A R Bolzoni, C Baserga, A Baj
Heparin-induced thrombocytopenia and thrombosis (HITT) represents a dramatic condition that is difficult to diagnose because of nuanced clinical presentation. Therefore, in every case of microvascular thrombosis during heparin-therapy prompt suspicion about HITT is necessary to avoid flap necrosis. We present a case of HITT which, as the 8 other articles reviewed, clearly shows that HITT is difficult to diagnose and complex to manage. Microvascular reconstruction is the first choice in head and neck reconstruction; unfortunately, dramatic outcomes in free flap surgery due to unpredictable thrombotic events are still reported in the English literature...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177336/nystagmus-intensity-and-direction-in-bow-and-lean-test-an-aid-to-diagnosis-of-lateral-semicircular-canal-benign-paroxysmal-positional-vertigo
#2
V Marcelli
The objective was to evaluate nystagmus intensity and direction (NID) during bow and lean test (BLT) in subjects suffering from idiopathic lateral semicircular canal benign paroxysmal positional vertigo (LSC-BPPV), in order to differentiate between the geotropic and the apogeotropic form and to determine the affected ear before using classic diagnostic procedures. The BLT was performed in 32 subjects affected by LSC-BPPV. "Nystagmus intensity" evaluation allows distinguishing the geotropic variant from the apogeotropic one, while the "nystagmus direction" allows identification of the side...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177335/cochlear-implantation-in-post-lingually-deafened-adults-and-elderly-patients-analysis-of-audiometric-and-speech-perception-outcomes-during-the-first-year-of-use
#3
S Ghiselli, S Nedic, S Montino, L Astolfi, R Bovo
The aim of this study was to analyse audiometric and speech perception outcomes after cochlear implantation (CI) in adult and elderly patients in the first year post-CI activation. We evaluated 42 subjects who underwent CI at the Otorhinolaryngological Clinic of Padua Hospital. The subjects enrolled were post-lingually deafened patients who were unilaterally implanted for bilateral, severe-to-profound hearing loss. The overall sample was divided into three groups according to the age at the time of implantation: group A (35-49 years), group B (50-64 years) and group C (≥ 65 years)...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177334/development-of-a-novel-italian-speech-in-noise-test-using-a-roving-level-adaptive-method-adult-population-based-normative-data
#4
P Canzi, M Manfrin, G Locatelli, P Nopp, M Perotti, M Benazzo
In recent years the increasing development of hearing devices has led to a critical analysis of the standard methods employed to evaluate hearing function. Being too far from reality, conventional investigation of hearing loss based on pure-tone threshold audiometry and on mono/disyllabic word lists, presented in quiet conditions, has been shown to be inadequate. A speech-in-noise test using a roving-level adaptive method employs target and competing signals varying in level in order to reproduce everyday life speaking conditions and explore a more complete sound range...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177333/high-definition-video-telescopic-rhinoplasty
#5
I Tasca, G Ceroni Compadretti, C Romano
Optical magnification has become an essential tool in rhinologic practice, especially following the popularisation of endoscopic procedures for nasal sinus surgery. We describe the use of VITOM(®) technology in rhinoplasty, which to our knowledge has not been reported in the international literature to date. This approach to rhinoplasty markedly improves visualisation of the surgical field, thereby improving the understanding of the procedures and enhancing the teaching environment. Since VITOM(®) technology works by combining the telescope with a standard endoscopic setting, video telescopic rhinoplasty may be easily and inexpensively performed in any ENT department provided with this instrumentation...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177332/a-comparative-study-on-oxidative-stress-role-in-nasal-breathing-impairment-and-obstructive-sleep-apnoea-syndrome
#6
D Passali, G Corallo, A Petti, M Longini, F M Passali, G Buonocore, L M Bellussi
Obstructive sleep apnoea syndrome (OSAS) is a sleep disorder that leads to metabolic abnormalities and increased cardiovascular risk. This study aimed to define the expression and clinical significance of biomarkers involved in oxidative stress in patients with OSAS. A prospective study was designed to compare outcomes of oxidative stress laboratory tests in three groups of subjects. The study involved the recruitment of three groups of subjects, 10 patients with obstructive sleep apnoea syndrome with AHI > 30; 10 patients suffering from snoring at night with AHI < 15; 10 patients with nasal respiratory impairment with AHI < 5...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177331/the-role-of-masseter-muscle-emg-during-dise-to-predict-the-effectiveness-of-mad-preliminary-results
#7
M R Marchese, E Scarano, G Rizzotto, C Grippaudo, G Paludetti
The use of a mandibular advancement device (MAD) increases the activity of the temporo-mandibular (TM) complex and masseter (MM) muscles with the risk of reducing treatment compliance. Predictors of treatment outcome are of importance in selecting patients who might benefit from MAD without side effects. The role of mandibular advancement (MA) during drug-induced sleep endoscopy (DISE) is controversial. In three cases (BMI < 30) affected by non-severe OSAS (AHI < 30 e/h), we recorded the surface EMG signal of MM activity during DISE...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177330/outcomes-of-interventional-sialendoscopy-for-obstructive-salivary-gland-disorders-an-italian-multicentre-study
#8
A Gallo, P Capaccio, M Benazzo, L De Campora, M De Vincentiis, P Farneti, M Fusconi, M Gaffuri, F Lo Russo, S Martellucci, F Ottaviani, G Pagliuca, G Paludetti, E Pasquini, L Pignataro, R Puxeddu, M Rigante, E Scarano, S Sionis, R Speciale, P Canzi
Interventional sialendoscopy has become the predominant therapeutic procedure for the management of obstructive salivary disorders, but only a few multicentre studies of large series of patients with a long-term follow-up have been published. This Italian multicentre study involved 1152 patients (553 females; mean age 50 years) who, after at least a clinical and ultrasonographic evaluation, underwent a total of 1342 diagnostic and interventional sialendoscopies, 44.6% of which involved the parotid gland. 12% (n = 138) of patients underwent multiple treatments...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177329/fibular-osteofasciocutaneous-flap-in-computer-assisted-mandibular-reconstruction-technical-aspects-in-oral-malignancies
#9
M Berrone, E Crosetti, P L Tos, M Pentenero, G Succo
Virtual surgical planning technology in head and neck surgery is witnessing strong growth. In the literature, the validity of the method from the point of view of accuracy and clinical utility has been widely documented, especially for bone modelling. To date, however, with its increased use in head and neck oncology, and consequently the increased need for bone and soft tissue reconstruction, is important to carry out the virtual programme considering not only bone reconstruction but also all aspects related to the reconstruction of soft tissue using composite flaps...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177328/head-and-neck-reconstruction-with-pedicled-flaps-in-the-free-flap-era
#10
R Mahieu, G Colletti, P Bonomo, G Parrinello, A Iavarone, G Dolivet, L Livi, A Deganello
Nowadays, the transposition of microvascular free flaps is the most popular method for management of head and neck defects. However, not all patients are suitable candidates for free flap reconstruction. In addition, not every defect requires a free flap transfer to achieve good functional results. The aim of this study was to assess whether pedicled flap reconstruction of head and neck defects is inferior to microvascular free flap reconstruction in terms of complications, functionality and prognosis. The records of consecutive patients who underwent free flap or pedicled flap reconstruction after head and neck cancer ablation from 2006 to 2015, from a single surgeon, in the AOUC Hospital, Florence Italy were analysed...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177327/functional-outcomes-of-supraglottic-squamous-cell-carcinoma-treated-by-transoral-laser-microsurgery-compared-with-horizontal-supraglottic-laryngectomy-in-patients-younger-and-older-than-65-years
#11
C M Chiesa Estomba, F A Betances Reinoso, A I Lorenzo Lorenzo, J L Fariña Conde, J Araujo Nores, C Santidrian Hidalgo
The treatment of supraglottic carcinoma remains a controversial issue. Five accepted surgical and non-surgical oncological treatments have been currently established: standard horizontal supraglottic laryngectomy (HSL), supraglottic CO2 laser microsurgery (TLM), transoral robotic surgery, radiotherapy alone and radiotherapy in combination with chemotherapy. Some studies have shown that complications of head and neck surgeries increase significantly in patients over 65 years compared to younger patients. We designed a retrospective analysis to assess the rate of complications and functional outcomes of patients treated by TLM and HSL in cases of T1-T3 supraglottic squamous cell carcinomas (SCC) in a tertiary University Hospital...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28177326/supracricoid-laryngectomy-for-recurrent-laryngeal-cancer-after-chemoradiotherapy-a-systematic-review-and-meta-analysis
#12
C A Leone, P Capasso, D Topazio, G Russo
Residual or recurrent laryngeal cancer after irradiation is a difficult clinical problem with a rate that ranges from 13% to 36% of cases. Supracricoid laryngectomy (SCL) with cricohyoidopexy (CHP) or cricohyoidoepiglottopexy (CHEP) provide reliable oncological and functional results for selected primary and recurrent patients with glottic and supraglottic carcinomas. We conducted a systematic review and meta-analysis to assess the oncological and functional outcomes of patients treated with open partial horizontal laryngectomy types IIa and IIb (CHEP, CHP) in terms of the recurrence of squamocellular cancer of the larynx after radiotherapy failure...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27600104/3d-curved-multiplanar-cone-beam-ct-reconstruction-for-intracochlear-position-assessment-of-straight-electrodes-array-a-temporal-bone-and-clinical-study
#13
D De Seta, P Mancini, F Y Russo, R Torres, I Mosnier, J L Bensimon, E De Seta, D Heymann, O Sterkers, D Bernardeschi, Y Nguyen
A retrospective review of post-op cone beam CT (CBCT) of 8 adult patients and 14 fresh temporal bones that underwent cochlear implantation with straight flexible electrodes array was performed to determine if the position of a long and flexible electrodes array within the cochlear scalae could be reliably assessed with CBCT. An oto-radiologist and two otologists examined the images and assessed the electrodes position. The temporal bone specimens underwent histological analysis for confirm the exact position...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27897275/an-ex-vivo-model-contributing-to-the-diagnosis-and-evaluation-of-new-drugs-in-cystic-fibrosis
#14
A M Di Lullo, M Scorza, F Amato, M Comegna, V Raia, L Maiuri, G Ilardi, E Cantone, G Castaldo, M Iengo
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the cystic fibrosis transmembrane regulator (CFTR) gene. About 2000 mutations have been described so far. We setup an ex vivo model of human nasal epithelial cells (HNECs) to study CF patients testing the effect of novel mutations and molecular therapies. We performed the sampling (by brushing), followed by culture and analysis of HNECs using a series of molecular techniques. We performed 50 brushings from CF patients and controls...
November 29, 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27897274/modelling-tumour-volume-variations-in-head-and-neck-cancer-magnetic-resonance-imaging-contribution-for-patients-undergoing-induction-chemotherapy
#15
N Dinapoli, T Tartaglione, F Bussu, R Autorino, F Miccichè, M Sciandra, E Visconti, C Colosimo, G Paludetti, V Valentini
Primary tumour volume evaluation has predictive value for estimating survival outcomes. Using volumetric data acquired by MRI in patients undergoing induction chemotherapy (IC) these outcomes were estimated before the radiotherapy course in head and neck cancer (HNC) patients. MRI performed before and after IC in 36 locally advanced HNC patients were analysed to measure primary tumour volume. The two volumes were correlated using the linear-log ratio (LLR) between the volume in the first MRI and the volume in the second...
November 29, 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27958603/a-connection-between-neurovascular-conflicts-within-the-cerebellopontine-angle-and-vestibular-neuritis-a-case-controlled-cohort-study
#16
B Loader, I Linauer, S Korkesch, I Krammer-Effenberger, V Zielinski, N Schibany, A Kaider, E Vyskocil, D Tscholakoff, P Franz
This retrospective, observer blinded case-control study aims to compare the prevalence of neurovascular conflicts (NVCs) of the vestibulocochlear nerve and the anterior inferior cerebellar artery (AICA) in patients presenting with clinical signs of acute vestibular neuritis with and without subsequent objective vestibular function loss (VFL). 58 acute cases of clinically suspected acute vestibular neuritis were investigated with same day cranial MRI at a tertiary referral centre and compared to 61 asymptomatic controls...
October 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27958602/severe-to-profound-deafness-may-be-associated-with-myh9-related-disease-report-of-4-patients
#17
P Canzi, A Pecci, M Manfrin, E Rebecchi, C Zaninetti, V Bozzi, M Benazzo
MYH9-related disease (MYH9-RD) is a rare genetic syndromic disorder characterised by congenital thrombocytopenia and is associated with the risk of developing progressive sensorineural hearing loss, nephropathy and presenile cataracts during childhood or adult life. All consecutive patients enrolled in the Italian Registry for MYH9-RD with severe to profound deafness were included in a retrospective study. The study population involved 147 Italian patients with MYH9-RD: hearing loss was identified in 52% of cases and only 4 patients (6%) presented severe to profound deafness at a mean age of 33 years...
October 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27958601/open-partial-horizontal-laryngectomies-is-it-time-to-adopt-a-modular-form-of-consent-for-the-intervention
#18
L Giordano, D Di Santo, E Crosetti, A Bertolin, G Rizzotto, G Succo, M Bussi
Nowadays, open partial horizontal laryngectomies (OPHLs) are well-established procedures for treatment of laryngeal cancer. Their uniqueness is the possibility to modulate the intervention intraoperatively, according to eventual tumour extension. An OPHL procedure is not easy to understand: there are several types of procedures and the possibility to modulate the intervention can produce confusion and lack of adherence to the treatment from the patient. Even if the surgery is tailored to a patient's specific lesion, a unified consent form that discloses any possible extensions, including a total laryngectomy, is still needed...
October 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27958600/comparison-between-videofluoroscopy-fiberoptic-endoscopy-and-scintigraphy-for-diagnosis-of-oro-pharyngeal-dysphagia
#19
B Fattori, P Giusti, V Mancini, M Grosso, M R Barillari, L Bastiani, S Molinaro, A Nacci
The purpose of this study was to compare videofluoroscopy (VFS), fiberoptic endoscopic evaluation of swallowing (FEES) and oro-pharyngo- oesophageal scintigraphy (OPES) with regards to premature spillage, post-swallowing residue and aspiration to assess the reliability of these tests for detection of oro-pharyngeal dysphagia. Sixty patients affected with dysphagia of various origin were enrolled in the study and submitted to VFS, FEES and OPES using a liquid and semi-solid bolus. As a reference, we used VFS...
October 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27958599/association-between-oral-habits-mouth-breathing-and-malocclusion
#20
C Grippaudo, E G Paolantonio, G Antonini, R Saulle, G La Torre, R Deli
The ratio of bad habits, mouth breathing and malocclusion is an important issue in view of prevention and early treatment of disorders of the craniofacial growth. While bad habits can interfere with the position of the teeth and normal pattern of skeletal growth, on the other hand obstruction of the upper airway, resulting in mouth breathing, changes the pattern of craniofacial growth causing malocclusion. Our crosssectional study, carried out on 3017 children using the ROMA index, was developed to verify if there was a significant correlation between bad habits/mouth breathing and malocclusion...
October 2016: Acta Otorhinolaryngologica Italica
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