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Graefe's Archive for Clinical and Experimental Ophthalmology

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https://www.readbyqxmd.com/read/28891028/the-use-of-optical-coherence-tomography-angiography-in-pachychoroid-spectrum-diseases-a-concurrent-comparison-with-dye-angiography
#1
Sibel Demirel, Özge Yanık, Hilal Nalcı, Figen Batıoğlu, Emin Özmert
PURPOSE: The study objective was to compare dye angiography and optical coherence tomography angiography (OCTA) in detecting choroidal neovascuarization (CNV) in patients presenting with pachychoroid features and flat irregular pigment epithelial detachment (PED). METHODS: Nineteen eyes of 17 patients, presenting with flat PED and pachychoroid features, and without age-related macular degeneration or any other degenerative change, were analyzed. Fuorescein angiography (FA)/Indocyanine green angiography (ICGA) and OCTA were performed during the same visit...
September 11, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28889226/stereopsis-and-fusion-in-anisometropia-according-to-the-presence-of-amblyopia
#2
Hyun Sun Jeon, Dong Gyu Choi
PURPOSE: To evaluate the level of stereopsis and fusion in patients with anisometropia according to the presence of amblyopia. METHODS: We included 107 children with anisometropia, divided into groups with non-amblyopic anisometropia (NA, n = 72) and amblyopic anisometropia (AA, n = 35). Normal subjects without anisometropia were enrolled in the control group (n = 73). Main outcome measures were the level of stereopsis and sensory fusion as evaluated by Titmus stereotest and Worth 4-dot test, respectively, using anisometropic glasses...
September 9, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28889224/relationship-between-choroidal-blood-flow-velocity-and-choroidal-thickness-in-patients-with-regression-of-acute-central-serous-chorioretinopathy
#3
LETTER
Michiyuki Saito, Kousuke Noda, Wataru Saito, Susumu Ishida
No abstract text is available yet for this article.
September 9, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28887638/a-new-strategy-to-sustained-release-of-ocular-drugs-by-one-step-drug-loaded-microcapsule-manufacturing-in-hydrogel-punctal-plugs
#4
Jiajun Xie, Changjun Wang, Qingyao Ning, Qi Gao, Changyou Gao, Zhongru Gou, Juan Ye
PURPOSE: To design an injectable hyaluronate (HA)-based hydrogel system that contains drug-loaded microcapsules as resorbable plugs to deliver ocular drugs. METHODS: In-situ drug-loaded, core-shell-structured chitosan (CS)@HA microcapsules were fabricated via HA hydrosol collecting in electrospun bead-rich CS fibers under continuous stirring. An injectable and cytocompatible hydrogel system with different degrees of chemical crosslinking maintained viscoelastic and sustained drug release for a long-term period of time at body temperature in vitro...
September 8, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28887584/ocular-perfusion-pressure-control-during-pars-plana-vitrectomy-testing-a-novel-device
#5
Tommaso Rossi, Giorgio Querzoli, Aldo Gelso, Giampiero Angelini, Alessandro Rossi, Paolo Corazza, Laura Landi, Serena Telani, Guido Ripandelli
PURPOSE: To study the efficacy of a novel device intended to control infusion pressure based on mean ocular perfusion pressure (MOPP) during pars plana vitrectomy (PPV). METHODS: An arm blood pressure cuff connected to a vitrectomy machine calculated mean arterial pressure (MAP), while a pressure sensor close to the infusion trocar measured intraocular pressure (IOP). MOPP was calculated in real time in 36 consecutive patients undergoing PPV, who were divided into two groups...
September 8, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28884344/coats-disease-not-such-a-smooth-ride
#6
EDITORIAL
Paolo Nucci
No abstract text is available yet for this article.
September 7, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28879420/estimated-incidence-of-high-altitude-retinal-hemorrhages
#7
LETTER
Gabriel Willmann, Andreas Schatz, Florian Gekeler, Maximilian Schultheiss
No abstract text is available yet for this article.
September 7, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28879555/effects-of-photodynamic-therapy-plus-intravitreal-aflibercept-with-subtenon-triamcinolone-injections-for-aflibercept-resistant-polypoidal-choroidal-vasculopathy
#8
LETTER
Dan Călugăru, Mihai Călugăru
No abstract text is available yet for this article.
September 6, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28875349/variations-in-optic-nerve-head-morphology-by-intraocular-pressure-in-open-angle-glaucoma
#9
Aaron Wong, Kaliopy Matheos, Zak Prime, Helen V Danesh-Meyer
PURPOSE: To compare optic disc topography in eyes in three intraocular pressure (IOP) groups of <15 mmHg, 15-20 mmHg, and ≥21 mmHg using spectral domain optical coherence tomography (SD-OCT) and confocal scanning laser ophthalmoscopy, adjusting for the degree of damage, as measured by retinal nerve fiber layer (RNFL) thickness and average visual field loss. METHODS: A total of 184 eyes of 112 patients with primary open-angle glaucoma were recruited into groups based on baseline untreated intraocular pressure (IOP) of <15 mmHg (normal-tension glaucoma [NTG], very low), 15-20 mmHg (NTG, medium), or ≥21 mmHg (high-tension glaucoma [HTG])...
September 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28875347/the-relationship-between-contrast-sensitivity-and-retinal-nerve-fiber-layer-thickness-in-patients-with-glaucoma
#10
Sarah Amanullah, Joseph Okudolo, Kamran Rahmatnejad, Shuai-Chun Lin, Sheryl S Wizov, Remy S Manzi Muhire, Lisa A Hark, Cindy X Zheng, Tingting Zhan, George L Spaeth
PURPOSE: To evaluate the correlation between contrast sensitivity (CS) and retinal nerve fiber layer (RNFL) in different areas of vision. METHODS: This report is a sub-analysis of a prospective, observational cohort study investigating changes in performance-based assessment, vision-related quality of life, and clinical measures in patients with moderate to advanced glaucoma. The study included 161 participants with at least a 2-year history of glaucoma who underwent annual testing for 4 years...
September 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28875340/corneal-features-in-ocular-graft-versus-host-disease-by-in-vivo-confocal-microscopy
#11
Tudor C Tepelus, Gloria B Chiu, Jyotsna Maram, Jianyan Huang, Vikas Chopra, SriniVas R Sadda, Olivia L Lee
PURPOSE: The purpose of our study was to determine the morphological features of the corneal epithelial layers, sub-basal nerve plexus and anterior stroma in patients with ocular graft-versus-host disease (oGVHD) compared to non-GVHD dry eyes and normal controls, using in vivo confocal microscopy (IVCM). METHODS: IVCM was used to capture central cornea images from eight volunteers with normal healthy eyes, ten patients with non-GVHD dry eye syndrome (DES) and 15 patients with clinically diagnosed oGVHD, in a cross-sectional study...
September 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28875282/refining-coats-disease-by-ultra-widefield-imaging-and-optical-coherence-tomography-angiography
#12
Alessandro Rabiolo, Alessandro Marchese, Riccardo Sacconi, Maria Vittoria Cicinelli, Andrea Grosso, Lea Querques, Giuseppe Querques, Francesco Bandello
PURPOSE: The purpose of our study was to describe ultra-widefield (UWF) imaging and optical coherence tomography angiography (OCT-A) findings in affected and fellow eyes of patients with Coats' disease. METHODS: Consecutive patients affected by Coats' disease were prospectively recruited at the Department of Ophthalmology, San Raffaele Hospital, Milan, Italy in this cross-sectional, observational study. Patients underwent UWF color fundus photographs, UWF green autofluorescence, UWF fluorescein angiography (FA), optical coherence tomography (OCT), with 3 × 3 mm and 6 × 6 mm OCT-A scans of the macula...
September 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28875245/the-relation-of-somatotypes-and-stress-response-to-central-serous-chorioretinopathy
#13
Roy Schwartz, Assaf Rozenberg, Anat Loewenstein, Michaella Goldstein
PURPOSE: To investigate a possible relationship between central serous chorioretinopathy (CSC) and specific body types and compositions (somatotypes), and to examine the cortisol stress response among CSC patients of different somatotypes in comparison with healthy subjects. METHODS: Prospective case-control study. A group of 28 patients with a previous or current diagnosis of CSC was compared with a group of 26 healthy subjects. Anthropometric measurements were used to estimate somatotype ratings in all subjects...
September 5, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28861686/bell-s-phenomenon-in-thyroid-associated-inferior-rectus-myopathy
#14
Yasuhiro Takahashi, Maria Suzanne Sabundayo, Hidenori Mito, Hidetaka Miyazaki, Hirohiko Kakizaki
PURPOSE: To examine Bell's phenomenon in patients with unilateral thyroid-associated inferior rectus myopathy and changes in this phenomenon after inferior rectus muscle recession. METHODS: This prospective interventional study included 12 patients who underwent inferior rectus muscle recession with or without nasal transposition. Bell's phenomenon was examined before and 3 months after surgery. The upper eyelid was held open by a finger to prevent complete eyelid closure...
September 1, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28861697/optical-coherence-tomography-angiography-in-acute-arteritic-and-non-arteritic-anterior-ischemic-optic-neuropathy
#15
Nicole Balducci, Mariachiara Morara, Chiara Veronese, Piero Barboni, Nicoletta Lelli Casadei, Giacomo Savini, Vincenzo Parisi, Alfredo A Sadun, Antonio Ciardella
PURPOSE: The purpose of our study was to describe the feature of acute non-arteritic or arteritic anterior ischemic optic neuropathy (NA-AION and A-AION) using optical coherence tomography angiography (OCT-A) and to compare it with fluorescein angiography (FA) and indocyanine green angiography (ICGA). METHODS: In this retrospective, observational case-control study four NA-AION patients and one A-AION patient were examined by FA, ICGA and OCT-A within 2 weeks from disease presentation...
August 31, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28856428/intraoperative-b-scan-ultrasonography-and-pars-plana-vitrectomy-for-severe-open-globe-injury-with-hemorrhagic-retinal-and-choroidal-detachment
#16
Nobuhiko Shiraki, Taku Wakabayashi, Tatsuhiko Sato, Hirokazu Sakaguchi, Kohji Nishida
PURPOSE: Our purpose was to report the initial clinical experience of intraoperative B-scan ultrasonography in combination with 25-gauge pars plana vitrectomy for severe open globe injury with hemorrhagic retinal and choroidal detachment. METHODS: Six eyes of six consecutive patients with severe open globe injury underwent intraoperative B-scan ultrasonography and 25-gauge pars plana vitrectomy at Osaka University Hospital in Japan. The feasibility of intraoperative B-scan ultrasonography, best-corrected visual acuity (BCVA), retinal reattachment, and intraoperative and postoperative complications were evaluated...
August 30, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28852825/incarceration-of-the-inferior-oblique-muscle-branch-of-the-oculomotor-nerve-in-patients-with-orbital-floor-trapdoor-fracture
#17
Yasuhiro Takahashi, Maria Suzanne Sabundayo, Hidetaka Miyazaki, Hidenori Mito, Hirohiko Kakizaki
PURPOSE: To examine the clinical characteristics of patients with concomitant incarceration of the inferior oblique muscle branch of the oculomotor nerve who had suffered from an orbital floor trapdoor fracture with orbital fat incarceration. METHODS: Fifty-nine patients were retrospectively reviewed. Concomitant inferior oblique muscle branch incarceration was diagnosed by inferior oblique muscle underaction on the Hess chart and a missing inferior oblique muscle branch on computed tomographic images on baseline examination...
August 29, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28842751/reply-to-the-letter-to-the-editor-two-year-results-of-treat-and-extend-regimen-with-aflibercept-for-polypoidal-choroidal-vasculopathy
#18
LETTER
Masahiro Morimoto, Hidetaka Matsumoto, Kensuke Mimura, Hideo Akiyama
No abstract text is available yet for this article.
August 25, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28840310/topical-cis-urocanic-acid-prevents-ocular-surface-irritation-in-both-ige-independent-and-mediated-rat-model
#19
Hanna-Mari Jauhonen, Jarmo Laihia, Olli Oksala, Johanna Viiri, Reijo Sironen, Päivi Alajuuma, Kai Kaarniranta, Lasse Leino
PURPOSE: Our purpose was to investigate the effect of locally administered cis-urocanic (cis-UCA) in two experimental models of allergic conjunctivitis. METHODS: The compound 48/80 (C48/80)-induced ocular irritation model (IgE-independent) and the ovalbumin (OA)-induced ocular allergy model (IgE-mediated) were used to test and compare the effect of cis-UCA on dexamethasone, ketotifen and olopatadine. In the C48/80 model, clinical severity scoring from photographs, immunohistochemical analysis of nuclear Ki-67 antigen to quantify actively proliferating epithelial cells and of caspase-3 enzyme to identify apoptotic activity in the conjunctival tissue were used...
August 24, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28836231/reduction-of-foveal-bulges-and-other-anatomical-changes-in-fellow-eyes-of-patients-with-unilateral-idiopathic-macular-hole-without-vitreomacular-pathologic-changes
#20
Barbara Delas, Gemma Julio, Álvaro Fernández-Vega, Ricardo P Casaroli-Marano, Jeroni Nadal
PURPOSE: To compare the foveal characteristics in fellow eyes (FE) of patients with unilateral idiopathic macular hole without vitreomacular pathologic changes with eyes of healthy controls. METHODS: Forty-seven FE and 52 eyes of 52 age- and sex-matched healthy controls were studied. Quantitative assessment of the dome-shaped appearance of the hyperreflective lines that represent external limiting membrane (ELM_bulge) and inner outer segment junctions (IS/OS_bulge) were made by optical coherence tomography (OCT) images...
August 23, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
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