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Nuclear Medicine Communications

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https://www.readbyqxmd.com/read/29049095/a-clinical-evaluation-of-the-impact-of-the-bayesian-penalized-likelihood-reconstruction-algorithm-on-pet-fdg-metrics
#1
Delphine Vallot, Olivier Caselles, Leonor Chaltiel, Anthony Fernandez, Erwan Gabiache, Lawrence Dierickx, Slimane Zerdoud, Mathilde Bauriaud, Frédéric Courbon
PURPOSE: The aim of this study was to evaluate the impact of using the Bayesian penalized likelihood (BPL) algorithm on a bismuth germanium oxide positron emission tomography (PET)/computed tomography (CT) system for F-FDG PET/CT exams in case of low injected activity and scan duration. MATERIALS AND METHODS: F-FDG respiratory gated PET/CT performed on 102 cancer patients, injected with ∼2 MBq/kg of F-FDG, were reconstructed using two algorithms: ordered subset expectation maximization (OSEM) and BPL...
October 18, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29040161/prognostic-factor-analysis-in-325-patients-with-graves-disease-treated-with-radioiodine-therapy
#2
Danrong Yang, Jianjun Xue, Wenxia Ma, Furong Liu, Yameng Fan, Jie Rong, Aimin Yang, Yan Yu
INTRODUCTION: I therapy is a choice for Graves' hyperthyroidism. Several factors that affect the success of I treatment in Graves' disease (GD) patients have been put forward. The aim of this retrospective study was to evaluate the factors influencing the success of I therapy and the occurrence of hypothyroidism after I therapy. PATIENTS AND METHODS: We reviewed 325 GD patients, who were well documented out of 779 cases, treated with I in the First Affiliated Hospital of Xi'an Jiaotong University between 2010 and 2016...
October 16, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29023336/correlation-between-functional-imaging-markers-derived-from-diffusion-weighted-mri-and-18f-fdg-pet-ct-in-esophageal-cancer
#3
Lucas Goense, Sophie E Heethuis, Peter S N van Rossum, Francine E M Voncken, Jan J W Lagendijk, Marnix G E H Lam, Chris H Terhaard, Richard van Hillegersberg, Jelle P Ruurda, Stella Mook, Astrid L H M W van Lier, Steven H Lin, Gert J Meijer
OBJECTIVE: Both the apparent diffusion coefficient (ADC) acquired by diffusion-weighted magnetic resonance imaging (DW-MRI) and the standardized uptake value (SUV), acquired by F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT), are well-established functional parameters in cancer imaging. Currently, it is unclear whether these two markers provide complementary prognostic and predictive information in esophageal cancer. The aim of this study was to evaluate the correlation between ADC and SUV in patients with esophageal cancer...
October 11, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29023335/radioprotective-effect-of-lycopene-on-the-gastrointestinal-tract-after-high-dose-radioiodine-administration-in-rat-models
#4
Murat Sadic, Fadimana N Aydinbelge, Nihat Yumusak, Emre Karakok, Aylin Akbulut, Gokhan Koca, Meliha Korkmaz
PURPOSE: The aim of this study was to evaluate the effect of lycopene against radioactive iodine (RAI)-related gastrointestinal tract acute damage in a rat model as a novel radioprotective agent. MATERIALS AND METHODS: Twenty Wistar albino rats were divided into two equal groups: group 1 was administered only RAI and group 2 was administered RAI and lycopene. All rats were killed 24 h after the last administration of the agents and the gastrointestinal tract organs were removed surgically for histopathological examination...
October 11, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28953209/improving-women-s-health-in-low-income-and-middle-income-countries-part-ii-the-needs-of-diagnostic-imaging
#5
Giuliano Mariani, Joanna Kasznia-Brown, Diana Paez, Miriam N Mikhail, Dina H Salama, Neerja Bhatla, Paola A Erba, Ravi Kashyap
No abstract text is available yet for this article.
October 11, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28922336/improving-women-s-health-in-low-income-and-middle-income-countries-part-i-challenges-and-priorities
#6
Giuliano Mariani, Joanna Kasznia-Brown, Diana Paez, Miriam N Mikhail, Dina H Salama, Neerja Bhatla, Paola A Erba, Ravi Kashyap
No abstract text is available yet for this article.
October 11, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28984816/reproducibility-of-differential-renal-function-measurement-using-technetium-99m-ethylenedicysteine-dynamic-renal-scintigraphy-a-french-prospective-multicentre-study
#7
Duc L Nguyen, Claire de Labriolle-Vaylet, Emmanuel Durand, Philippe X Fernandez, François Bonnin, Daniel Deliu, Florent L Besson, Philippe Chaumet-Riffaud
OBJECTIVE: Dynamic renal scintigraphy remains the gold standard for assessing differential renal function (DRF). Recently, technetium-99m-ethylenedicysteine (Tc-EC) was shown to be valuable and had similar quality images as technetium-99m-mercaptoacetyltriglycine (Tc-MAG3). However, its reproducibility has never been confirmed. The aim of this study was to perform the first evaluation of Tc-EC reproducibility for assessing DRF in children who were referred for hydronephrosis or urinary tract dilatation...
October 3, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28984815/benefits-of-respiratory-gated-18f-fdg-pet-acquisition-in-lung-disease
#8
Pascal Bailly, Roger Bouzerar, Trevor Shields, Marc-Etienne Meyer, Joël Daouk
BACKGROUND: Fluorine-18-fluorodeoxyglucose (F-FDG) PET/computed tomography (CT) is a reliable imaging modality for the diagnosis of malignant lung nodules and to assess the latter's prognosis. However, physiological respiratory motion deteriorates PET images and thus decreases the technique's diagnostic and prognostic values. This issue can be overcome by applying respiratory gating to the F-FDG PET/CT acquisitions. PURPOSE: The aim of this study was to evaluate the ability of respiratory-gated F-FDG PET/CT to diagnose malignant lung nodules and to predict recurrence and patient survival...
October 3, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28984814/clinical-utility-of-18f-fdg-pet-ct-in-low-18f-fdg-avidity-breast-cancer-subtypes-comparison-with-breast-us-and-mri
#9
Hye Lim Park, Ie Ryung Yoo, Joo Hyun O, Hyoungwoo Kim, Sung Hun Kim, Bong Joo Kang
OBJECTIVE: The aim of this study was to evaluate the diagnostic performance of fluorine-18-fluorodeoxyglucose (F-FDG) PET/CT in initial axillary lymph node (ALN) staging and tumor recurrence in breast cancer subtypes with low F-FDG avidity in comparison with breast ultrasonography (US) and/or MRI. PATIENTS AND METHODS: A total of 491 PET/CT exams from 192 patients with biopsy-proven breast cancer subtypes with low F-FDG avidity were enrolled retrospectively. Nodal status on staging and locoregional recurrence or metastasis on surveillance was confirmed either by pathology or by further clinical follow-up...
October 3, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28984813/dual-isotope-subtraction-spect-ct-in-parathyroid-localization
#10
Anna-May Woods, Alison A Bolster, Sai Han, Fat-Wui Poon, David Colville, John Shand, James B Neilly
OBJECTIVE: The aim of this study was to investigate the accuracy of locating parathyroid adenomas using dual-Isotope subtraction single-photon emission computed tomography-computed tomography (SPECT-CT) in comparison with clinical follow-up and pathology findings from surgery. PATIENTS AND METHODS: A retrospective cohort study of dual-isotope subtraction SPECT-CT was carried out on 224 consecutive patients who were diagnosed with primary hyperparathyroidism. All the patients were injected with 20 MBq of iodine-123-iodide, followed 20 min later by 900 MBq of technetium-99m-sestamibi...
October 3, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28984812/factors-associated-with-diffusely-increased-renal-uptake-of-tc-99m-diphosphono-propanedicarboxylic-acid-on-bone-scintigraphy-in-patients-with-end-stage-renal-disease
#11
Keunyoung Kim, Seong-Jang Kim, Sang H Song, In-Joo Kim, Kyoungjune Pak, So J Kim, Senghyeon Shin, Bum S Kim
OBJECTIVE: We aimed to determine the factors contributing toward diffusely increased renal uptake on bone scintigraphy using technetium-99m (Tc-99m) diphosphono-propanedicarboxylic acid (DPD) in patients with end-stage renal disease. PATIENTS AND METHODS: One-hundred and forty-three bone scintigraphies, performed between June 2007 and July 2013, in 135 patients with chronic kidney disease were analyzed retrospectively, including 22 bone scintigraphies (15 patients; eight women; seven men) with glomerular filtration rates less than 15 ml/min/1...
October 3, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28957842/comparison-of-68ga-psma-pet-ct-and-multiparametric-mri-for-staging-of-high-risk-prostate-cancer68ga-psma-pet-and-mri-in-prostate-cancer
#12
Shruti Tulsyan, Chandan J Das, Madhavi Tripathi, Amlesh Seth, Rajeev Kumar, Chandrasekhar Bal
INTRODUCTION: We carried out this study to compare Glu-NH-CO-NH-Lys-(Ahx) [Ga(HBED-CC)] [Ga prostate-specific membrane antigen-11 (PSMA-11)] PET with multiparametric MRI (mpMRI) for the staging of high-risk prostate cancer. PATIENTS AND METHODS: This was a prospective study in which 36 patients with high-risk prostate cancer were included. The criteria for inclusion were biopsy-proven prostate cancer with a serum prostate specific antigen of at least 20 and/or Gleason's score of at least 8...
September 27, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28957841/dynamic-risk-stratification-for-predicting-the-recurrence-in-differentiated-thyroid-cancer
#13
Elgin Ozkan, Cigdem Soydal, Demet Nak, Nuriye O Kucuk, Kemal M Kir
AIM: To analyze the predictive value of the dynamic risk stratification (DRS) system for assessing the risk of recurrent/persistent disease in our large group of differentiated thyroid carcinoma (DTC) patients. PATIENTS AND METHODS: We retrospectively included 2184 consecutive patients who received radioiodine ablation therapy following a total or near total thyroidectomy in our department between 1998 and 2014. The American Thyroid Association (ATA) classification was used for initial risk classification...
September 27, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28957840/the-efficacy-of-the-available-peptide-receptor-radionuclide-therapy-for-neuroendocrine-tumors-a-meta-analysis
#14
Shorouk F Dannoon, Saud A Alenezi, Abdelhamid H Elgazzar
AIM: This study was carried out to compare the efficacy of Y, Lu, and combination of both radiotracers (tandem) peptide receptor radionuclide therapy (PRRT) in patients with inoperable and metastatic neuroendocrine tumors. MATERIALS AND METHODS: Systematic searches of PubMed and SciVerse Scopus databases were performed till December of 2016. The data were categorized into three groups: Y-PRRT, Lu-PRRT, and tandem-PRRT. Each group was subdivided on the basis of the response criteria used: Response Evaluation Criteria in Solid Tumors (RECIST) or Southwest Oncology Group (SWOG) criteria...
September 27, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28953211/clinical-response-to-radioactive-iodine-therapy-for-prophylactic-central-neck-dissection-is-not-superior-to-total-thyroidectomy-alone-in-cn0-patients-with-papillary-thyroid-cancer
#15
Lin Bai, Qiang Wen, Wenqi Zhang, Tianyu Yu, Lina Zhao, Ji Bin
OBJECTIVE: Prophylactic central neck dissection (pCND) is controversial in papillary thyroid carcinoma (PTC) without clinical positive lymph nodes. The aim of this study was to investigate the effect of radioactive iodine (RAI) therapy on the clinical outcome in clinically node-negative (cN0) PTC patients treated with total thyroidectomy (TT) alone or in combination with pCND. PATIENTS AND METHODS: One-hundred and sixty-seven cN0 PTC patients who underwent TT alone (TT) or in combination with pCND (TT+pCND) in our hospital from January 2014 to August 2015 were evaluated retrospectively...
September 25, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28953208/the-utility-of-18f-fdg-pet-ct-for-the-diagnosis-of-adrenal-metastasis-in-lung-cancer-a-prisma-compliant-meta-analysis
#16
Qiang Wu, Wuxia Luo, Yaqin Zhao, Feng Xu, Qinghua Zhou
OBJECTIVES: The aim of the present meta-analysis was to systematically evaluate the overall diagnostic accuracy of F-FDG PET/CT for the detection of adrenal metastasis in lung cancer. PATIENTS AND METHODS: A comprehensive literature search of Medline (PubMed), Embase, Web of Science, Cochrane, and China National Knowledge Infrastructure databases published through 10 January 2017 on the role of F-FDG PET/CT in evaluating adrenal mass in lung cancer patients was performed...
September 25, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28953207/a-proof-of-concept-study-analyzing-the-clinical-utility-of-fluorine-18-sodium-fluoride-pet-ct-in-skeletal-staging-of-oncology-patients-with-end-stage-renal-disease-on-dialysis
#17
Sharjeel Usmani, Fahad Marafi, Abdulredha Esmail, Najeeb Ahmed
PURPOSE: The quality of conventional bone scintigraphy can be poor in patients with end-stage renal disease (ESRD). Fluorine-18-sodium fluoride (F-NaF) PET-computed tomography (CT) has rapid single-pass extraction, fast clearance from the soft tissues and a better target to background ratio. The aim of the present study is to preliminarily assess the superior tracer kinetics of F-NaF in ESRD patients. MATERIALS AND METHODS: A cohort comprising of 13 patients with ESRD (mean age 65...
September 25, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28926500/occipital-lobe-and-posterior-cingulate-perfusion-in-the-prediction-of-dementia-with-lewy-body-pathology-in-a-clinical-sample
#18
Angus M J Prosser, Livia Tossici-Bolt, Christopher M Kipps
OBJECTIVE: The aim of this study was to investigate the diagnostic value of occipital lobe and posterior cingulate perfusion in predicting dopamine transporter imaging outcome using a quantitative measure of analysis. PATIENTS AND METHODS: In total, 99 patients with cognitive complaints who had undergone both technetium-99m-hexamethylpropyleneamine oxime single-photon emission computed tomography (Tc-HMPAO SPECT) and I ioflupane (I-FP-CIT also called DaTSCAN) imaging in a dementia diagnostic center were analyzed...
September 18, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28922334/common-malignant-brain-tumors-can-18f-fdg-pet-ct-aid-in-differentiation
#19
Nilendu C Purandare, Ameya Puranik, Sneha Shah, Archi Agrawal, Tejpal Gupta, Aliasgar Moiyadi, Prakash Shetty, Epari Shridhar, Rakesh Jalali, Venkatesh Rangarajan
OBJECTIVES: The objectives of this study were to evalute the metabolic characteristics of common malignant space-occupying lesions (SOL) of the brain and to determine the utility of fluorine-18-fluorodeoxyglucose (F-FDG) PET/CT in differentiating between the common types of malignant brain SOL. PATIENTS AND METHODS: All patients with brain SOL who were referred for an F-FDG PET/CT scan by a multidisciplinary team were included in this retrospective study. The metabolic characteristics of the brain lesions in the form of maximum standardized uptake value (SUVmax) along with tumor-to-background activity ratios were determined and differences were compared using nonparametric statistical tests...
September 15, 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28914686/rhenium-188-as-a-therapeutic-radionuclide-in-low-income-and-middle-income-countries
#20
Ajit Shinto, Ambi M R Pillai
No abstract text is available yet for this article.
September 15, 2017: Nuclear Medicine Communications
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