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Cephalalgia: An International Journal of Headache

Céline Melin, Florian Jacquot, Nicolas Vitello, Radhouane Dallel, Alain Artola
INTRODUCTION: Within superficial trigeminal nucleus caudalis (Sp5C) (laminae I/II), meningeal primary afferents project exclusively to lamina I, whereas nociceptive cutaneous ones distribute in both lamina I and outer lamina II. Whether such a relative absence of meningeal inputs to lamina II represents a fundamental difference from cutaneous pathways in the central processing of sensory information is still unknown. METHODS: We recorded extracellular field potentials in the superficial Sp5C of anesthetised rats evoked by electrically stimulating the dura mater, to selectively assess the synaptic transmission between meningeal primary afferents and second-order Sp5C neurons, the first synapse in trigeminovascular pathways...
October 5, 2016: Cephalalgia: An International Journal of Headache
Magne Geir Bøe, Erik Thortveit, Anita Vatne, Åse Mygland
BACKGROUND: Knowledge about long-term outcomes after medication withdrawal therapy for chronic headache, including tension type and migraine headache is lacking. METHODS: We re-examined 56 patients an average of nine years after they participated in a medication withdrawal study with a one-year follow-up. We collected and compared data on headache, use of medication, quality of life, quality of sleep, anxiety, depression, and labor participation one and nine years after the start of withdrawal therapy...
October 5, 2016: Cephalalgia: An International Journal of Headache
Sylvie Streel, Anne-Françoise Donneau, Nadia Dardenne, Axelle Hoge, Adelin Albert, Jean Schoenen, Michèle Guillaume
BACKGROUND: Metabolic syndrome (MetS) and migraine are known to be associated. This study assessed the risk of MetS and its clinical characteristics in migraine with aura (MA) and without aura (MO) based on a large-scale cross-sectional survey. METHODS: The study material consisted of 751 participants in the Nutrition, Environment and CardioVascular Health (NESCaV) survey. Diagnosis of migraine was based on the ef-ID migraine questionnaire and MetS was defined according to the Revised-Adult Treatment Panel III criteria...
October 4, 2016: Cephalalgia: An International Journal of Headache
Denys Fontaine, Serge Blond, Christian Lucas, Jean Regis, Anne Donnet, Stéphane Derrey, Evelyne Guegan-Massardier, Bechir Jarraya, Bich Dang-Vu, Frederic Bourdain, Dominique Valade, Caroline Roos, Christèle Creach, Stéphan Chabardes, Pierric Giraud, Jimmy Voirin, Jocelyne Bloch, Alda Rocca, Sophie Colnat-Coulbois, Francois Caire, Coralie Roger, Sylvie Romettino, Michel Lanteri-Minet
BACKGROUND: Occipital nerve stimulation (ONS) has been proposed to treat chronic medically-intractable cluster headache (iCCH) in small series of cases without evaluation of its functional and emotional impacts. METHODS: We report the multidimensional outcome of a large observational study of iCCH patients, treated by ONS within a nationwide multidisciplinary network ( NCT01842763), with a one-year follow-up. Prospective evaluation was performed before surgery, then three and 12 months after...
October 3, 2016: Cephalalgia: An International Journal of Headache
Frank Andrasik, Licia Grazzi, Domenico D'Amico, Emanuela Sansone, Matilde Leonardi, Alberto Raggi, Francisco Salgado-García
BACKGROUND: Mindfulness refers to a host of procedures that have been practiced for centuries, but only recently have begun to be applied to varied pain conditions, with the most recent being headache. METHODS: We reviewed research that incorporated components of mindfulness for treating pain, with a more in depth focus on headache disorders. We also examined literature that has closely studied potential physiological processes in the brain that might mediate the effects of mindfulness...
September 30, 2016: Cephalalgia: An International Journal of Headache
Khatera Ibrahimi, Steve Vermeersch, Pascal Frederiks, Vincent Geldhof, Cedric Draulans, Linde Buntinx, Emmanuel Lesaffre, Antoinette MaassenVanDenBrink, Jan de Hoon
BACKGROUND: Migraine is much more common in females than in males, and occurrence is associated with changes in female sex hormones. Calcitonin gene-related peptide (CGRP) plays a key role in migraine, and variations in female sex hormones may affect CGRP sensitivity and/or production. OBJECTIVES: Investigate repeatability, gender differences, influence of the menstrual cycle and of migraine on CGRP-dependent changes in dermal blood flow (DBF). METHODS: CGRP-dependent increases in DBF were assessed using laser Doppler perfusion imaging after topical application of 300 or 1000 µg capsaicin on the forearm of healthy subjects and migraine patients...
September 28, 2016: Cephalalgia: An International Journal of Headache
Francesca Camia, Livia Pisciotta, Giovanni Morana, Maria Cristina Schiaffino, Salvatore Renna, Paola Carrera, Maurizio Ferrari, Maria Giuseppina Baglietto, Edvige Veneselli, Laura Siri, Maria Margherita Mancardi
INTRODUCTION: Variants in the CACNA1A gene on chromosome 19p13 result in a spectrum of neurological phenotypes ranging from familial or sporadic hemiplegic migraine to congenital or progressive encephalopathies. Patients with CACNA1A variants often show acute attacks with ataxia or hemiplegia till coma, sometimes related to unilateral brain oedema. No guidelines for the medical management of these attacks are available since treatment is empiric, and many cases do not respond to common antimigraine drugs...
September 19, 2016: Cephalalgia: An International Journal of Headache
Kun-Hsien Chou, Fu-Chi Yang, Jong-Ling Fuh, Chen-Yuan Kuo, Yi-Hsin Wang, Jiing-Feng Lirng, Yung-Yang Lin, Shuu-Jiun Wang, Ching-Po Lin
BACKGROUND: Previous imaging studies on the pathogenesis of cluster headache (CH) have implicated the hypothalamus and multiple brain networks. However, very little is known regarding dynamic bout-associated, large-scale resting state functional network changes related to CH. METHODS: Resting-state functional magnetic resonance imaging data were obtained from CH patients and matched controls. Data were analyzed using independent component analysis for exploratory assessment of the changes in intrinsic brain networks and their relationship between in-bout and out-of-bout periods, as well as correlations with clinical observations...
September 7, 2016: Cephalalgia: An International Journal of Headache
Álvaro Gutiérrez-Viedma, Nuria González-García, Miguel Yus, Manuela Jorquera, Jesús Porta-Etessam, Héctor García-Moreno, David García-Azorín, María-Luz Cuadrado
INTRODUCTION: Epicrania fugax (EF) is a primary headache whose main feature is the dynamic character of the pain. EF pain typically moves across different dermatomes in a linear or zigzag trajectory. Recently, a facial variant of EF has been described, with the pain starting in the lower face and radiating upwards. AIM: We report eight patients with an EF-type of pain of facial location and either upward or downward radiation. METHODS: For each patient, we recorded relevant demographic and clinical data...
September 6, 2016: Cephalalgia: An International Journal of Headache
Tal Eidlitz-Markus, Shirit Zolden, Yishai Haimi-Cohen, Avraham Zeharia
OBJECTIVE: To compare comorbidities between migraine and tension headache in patients treated in a tertiary pediatric headache clinic. METHODS: Files of patients with migraine or tension headache attending a pediatric headache clinic were retrospectively reviewed for the presence of organic comorbidities. Additionally, patients were screened with the self-report Strengths and Difficulties Questionnaire to identify nonorganic comorbidities. If necessary, patients were referred to a pediatric psychiatrist, psychologist or social worker for further evaluation...
September 1, 2016: Cephalalgia: An International Journal of Headache
Patricia De la Riva, Naiara Andres-Marín, Nora Gonzalo-Yubero, Mikel Tainta-Cuezva, Nerea Caminos, Miguel Ángel Urtasun-Ocariz, Jose Félix Martí-Massó
No abstract text is available yet for this article.
September 1, 2016: Cephalalgia: An International Journal of Headache
(no author information available yet)
No abstract text is available yet for this article.
September 1, 2016: Cephalalgia: An International Journal of Headache
Anna Ambrosini, Aliaksei Kisialiou, Gianluca Coppola, Livio Finos, Delphine Magis, Francesco Pierelli, Jean Schoenen
BACKGROUND: Many studies report a habituation deficit of visual evoked potentials (VEP) and/or increased intensity dependence of auditory evoked cortical potentials (IDAP) in episodic migraine patients between attacks. These findings have a pathophysiological interest, but their diagnostic utility is not known. AIMS: To perform an audit on a large database of interictal VEP and IDAP recordings in episodic migraine patients and evaluate their diagnostic accuracy...
August 31, 2016: Cephalalgia: An International Journal of Headache
Michele Viana, Grazia Sances, Mattias Linde, Natascia Ghiotto, Elena Guaschino, Marta Allena, Salvatore Terrazzino, Giuseppe Nappi, Peter J Goadsby, Cristina Tassorelli
BACKGROUND: A detailed evaluation of migraine aura symptoms is crucial for classification issues and pathophysiological discussion. Few studies have focused on the detailed clinical aspects of migraine aura. METHODS: We conducted a prospective diary-based study of migraine aura features including presence, quality, laterality, duration of each aura symptom, their temporal succession; presence of headache and its temporal succession with aura. RESULTS: Seventy-two patients completed the study recording the characteristics of three consecutive auras (n = 216 auras)...
August 29, 2016: Cephalalgia: An International Journal of Headache
Ç Aktan, Ö Özgür, T Sindel, B Dora
INTRODUCTION: Headache is a frequent but neglected side effect of angiography, and the criteria for angiography related headache have been based on only a few studies. METHODS: One-hundred and thirty nine patients who underwent cerebral angiography and 30 controls who underwent peripheral angiography participated in this prospective, non-randomized, case-control study. Participants were instructed to tell the angiography staff in case a headache developed and were questioned about their headache just after, 24 hours after, and one week after angiography...
August 23, 2016: Cephalalgia: An International Journal of Headache
Marjolijn J Sorbi, Yannick Balk, Annet M Kleiboer, Emile Gm Couturier
AIM: This study examined the change over 20 months in 178 participants with frequent episodic migraine under adequate treatment as usual, who had completed online behavioural training (oBT) in migraine self-management either directly (group 1, n = 120) or after 10 months of watchful waiting (group 2, n = 58). METHODS: Participants completed questionnaires and an online headache diary and migraine monitor following the International Classification of Headache Disorders at T0 (baseline), T1 (post-training), T2 (6-month follow-up; extended baseline in group 2), T3 (post-training, group 2 only) and T4 (group 1: 16-month follow-up; group 2: 6-month follow-up)...
August 23, 2016: Cephalalgia: An International Journal of Headache
Elisa Rubino, Alessandro Vacca, Flora Govone, Annalisa Gai, Silvia Boschi, Milena Zucca, Paola De Martino, Salvatore Gentile, Lorenzo Pinessi, Innocenzo Rainero
BACKGROUND AND AIMS: Adiponectin, leptin, and resistin are adipocyte-derived secretory factors involved in endothelial function, weight, inflammation, and insulin resistance. Recent studies suggested a role for adipokines in episodic migraine as mediators of inflammatory processes. The aim of this study was to investigate plasma concentrations of adiponectin, leptin, and resistin in patients with chronic migraine. MATERIALS AND METHODS: Twenty-seven chronic migraineurs (20 females, 7 males; mean age 49...
August 22, 2016: Cephalalgia: An International Journal of Headache
Gordian Hamerla, Peter Kropp, Bianca Meyer, Alessandro Rocco, Tim P Jürgens, Uwe Walter
INTRODUCTION: The involvement of the serotonergic system of the brainstem raphe in the pathogenesis of migraine is discussed. Here we studied brainstem alterations in migraineurs using transcranial sonography and examined their relation to clinical features and self-medication. METHODS: We investigated 51 migraineurs (11 men, 40 women, mean age 29.7 ± 11.9 years) and 32 healthy individuals without history of headache or depressive disorder (eight men, 24 women, mean age 34...
August 17, 2016: Cephalalgia: An International Journal of Headache
Xiao-Ying Yuan, Sheng-Bo Yu, Cong Liu, Qiang Xu, Nan Zheng, Jian-Fei Zhang, Yan-Yan Chi, Xu-Gang Wang, Xiang-Tao Lin, Hong-Jin Sui
OBJECTIVE: We aimed to investigate the morphological changes and potential correlation between chronic headaches and the rectus capitis posterior minor muscle (RCPmi). METHODS: Comparison of RCPmi between patients with chronic headaches and healthy adult volunteers were collected using magnetic resonance imaging (MRI) and Mimics software. RESULTS: Among the 235 MRI images analyzed, the data between the two groups were considered statistically significant...
August 17, 2016: Cephalalgia: An International Journal of Headache
Enrico B Arkink, Nicole Schmitz, Guus G Schoonman, Jorine A van Vliet, Joost Haan, Mark A van Buchem, Michel D Ferrari, Mark C Kruit
OBJECTIVE: To evaluate the presence, localization, and specificity of structural hypothalamic and whole brain changes in cluster headache and chronic paroxysmal hemicrania (CPH). METHODS: We compared T1-weighted magnetic resonance images of subjects with cluster headache (episodic n = 24; chronic n = 23; probable n = 14), CPH (n = 9), migraine (with aura n = 14; without aura n = 19), and no headache (n = 48). We applied whole brain voxel-based morphometry (VBM) using two complementary methods to analyze structural changes in the hypothalamus: region-of-interest analyses in whole brain VBM, and manual segmentation of the hypothalamus to calculate volumes...
August 16, 2016: Cephalalgia: An International Journal of Headache
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