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International Journal of Cardiology

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https://www.readbyqxmd.com/read/29242100/takotsubo-is-not-a-cardiomyopathy
#1
Francesco Pelliccia, Gianfranco Sinagra, Perry Elliott, Guido Parodi, Cristina Basso, Paolo G Camici
Unraveling the mechanisms underlying Takotsubo (TTS) leads to question the current inclusion of the condition within the spectrum of cardiomyopathies. Indeed, the clinical presentation and pathophysiology of TTS clearly differ from cardiomyopathies, i.e. diseases of heart muscle unexplained by abnormal loading conditions or coronary artery disease, which cannot recover spontaneously and may cause sudden death often in minimally symptomatic individuals or result in a gradual deterioration in ventricular function and end-stage heart failure...
December 9, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29229371/measuring-no-production-rate-from-l-arginine-in-melas-by-mass-spectrometry-based-approaches-gc-ms-or-lc-ms-ms
#2
LETTER
Dimitrios Tsikas
No abstract text is available yet for this article.
December 8, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29242099/downregulation-of-circulating-mots-c-levels-in-patients-with-coronary-endothelial-dysfunction
#3
Qing Qin, Silvia Delrio, Junxiang Wan, R Jay Widmer, Pinchas Cohen, Lilach O Lerman, Amir Lerman
BACKGROUND: MOTS-c is one of the newly identified mitochondrial-derived peptides which play a role in regulating metabolic homeostasis. The current study aimed to investigate whether circulating MOTS-c levels are also associated with endothelial dysfunction(ED) in patients without significant structural coronary lesions. METHODS: Forty patients undergoing coronary angiography and endothelial function testing for clinical indications of recurrent angina with no structural coronary lesions were included in the study...
December 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29229372/invasive-and-noninvasive-hemodynamic-assessment-in-adults-with-fontan-palliation
#4
Alexander C Egbe, Heidi M Connolly, Nathaniel W Taggart, Mohamad Al-Otaibi, Barry A Borlaug
BACKGROUND/OBJECTIVES: Although echocardiographic-Doppler cardiac index (CI) assessment is widely used to guide heart failure management in patients with biventricular circulation, this application has not been studied in the Fontan population. The objective of this study was to: (1) determine the correlation between Doppler and cardiac catheterization CI calculation; (2) determine the association between Doppler CI and the occurrence of Fontan failure. METHODS: Retrospective review of adult Fontan patients followed at Mayo Clinic Adult Congenital Heart Disease program, 1994-2015...
December 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29224925/incidence-and-clinical-characteristics-of-sudden-cardiac-death-in-adult-congenital-heart-disease
#5
Benjamin Moore, Christopher Yu, Irina Kotchetkova, Rachael Cordina, David S Celermajer
BACKGROUND: The life expectancy of adults with congenital heart disease (CHD) has significantly improved in recent decades, with non-cardiovascular causes of death now competing with traditional cardiovascular causes. The risk of sudden cardiac death (SCD), a devastating event, still remains elevated above that of the general population. METHODS: We reviewed 2935 patients in our adult CHD database (age≥16years, seen at least once in our centre) and documented all cases of SCD between 2000-2015...
December 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29224924/prevalence-of-spontaneous-brugada-ecg-pattern-recorded-at-standard-intercostal-leads-a-meta-analysis
#6
Shaobo Shi, Hector Barajas-Martinez, Tao Liu, Yaxun Sun, Bo Yang, Congxin Huang, Dan Hu
OBJECTIVE: Typical Brugada ECG pattern is the keystone in the diagnosis of Brugada syndrome. However, the exact prevalence remains unclear, especially in Asia. The present study was designed to systematically evaluate the prevalence of spontaneous Brugada ECG pattern recorded at standard leads. METHODS: We searched the Medline, Embase and Chinese National Knowledge Infrastructure (CNKI) for studies of the prevalence of Brugada ECG pattern, published between Jan 1, 2003, and September 1, 2016...
December 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29221861/prosthetic-valve-endocarditis-in-patients-on-hemodialysis
#7
LETTER
Jinmiao Chen, Kui Hu, Jun Li, Tao Hong, Chunsheng Wang
No abstract text is available yet for this article.
December 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29203210/indoxyl-sulfate-upregulates-the-cannabinoid-type-1-receptor-gene-via-an-atf3-c-jun-complex-mediated-signaling-pathway-in-the-model-of-uremic-cardiomyopathy
#8
Yu-Juei Hsu, Shih-Che Hsu, Yung-Lung Chang, Shih-Ming Huang, Chun-Che Shih, Chien-Sung Tsai, Chih-Yuan Lin
BACKGROUND: The risk of cardiovascular disease is notably increased in patients with chronic kidney disease (CKD) and cannabinoid receptor type 1 (CB1R) plays an important role in the development of uremic cardiomyopathy. However, the molecular mechanism underlying the uremic toxin-induced upregulation of CB1R remains elusive. METHODS: The expression of the ATF3/c-Jun complex and CB1R in both in vivo and in vitro models of CKD were measured. We also determined the impact of the ATF3/c-Jun complex on CB1R expression by transfecting H9c2 cells with dominant negative mutants of ATF3 or c-Jun...
December 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29208425/serum-uric-acid-as-a-potential-marker-for-heart-failure-risk-in-men-on-antihypertensive-treatment-the-british-regional-heart-study
#9
S Goya Wannamethee, Olia Papacosta, Lucy Lennon, Peter H Whincup
The role of serum uric acid (SUA) as a prognostic marker for incident heart failure (HF) in hypertensive subjects is uncertain. We have prospectively examined the relationship between SUA and incident HF in 3440 men aged 60-79years separately in those on and not on antihypertensive treatment who were followed up for a mean period of 15years. Men on SUA lowering drugs and those with history of HF or myocardial infarction were excluded. There were 260 incident HF cases. The men were divided into three groups of SUA concentrations/levels (<350, 350-410 and >410μmol/L)...
November 28, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29203209/comparative-efficacy-of-two-paclitaxel-coated-balloons-with-different-excipient-coatings-in-patients-with-coronary-in-stent-restenosis-a-pooled-analysis-of-the-intracoronary-stenting-and-angiographic-results-optimizing-treatment-of-drug-eluting-stent-in-stent
#10
Roisin Colleran, Michael Joner, Sebastian Kufner, Felix Altevogt, Franz-Josef Neumann, Mohamed Abdel-Wahab, Janika Bohner, Christian Valina, Gert Richardt, Bernhard Zrenner, Salvatore Cassese, Tareq Ibrahim, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Robert A Byrne
BACKGROUND: Angioplasty with paclitaxel-coated balloons (PCB) is recommended for treatment of patients with coronary in-stent restenosis (ISR) according to European clinical practice guidelines. Most clinical trials have investigated iopromide-based PCB and there is a paucity of data comparing efficacy against butyryl-tri-hexyl citrate (BTHC)-based PCB. Our aim was to compare the performance of two widely-used PCB in the treatment of coronary ISR. METHODS: We analysed patients treated with BTHC- or iopromide-PCB for treatment of drug-eluting stent ISR in the setting of 2 consecutive trials with identical inclusion and exclusion criteria...
November 28, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29221862/physical-activity-sedentary-time-tv-viewing-physical-fitness-and-cardiovascular-disease-risk-in-adolescents-the-helena-study
#11
Alan R Barker, Luis Gracia-Marco, Jonatan R Ruiz, Manuel J Castillo, Raquel Aparicio-Ugarriza, Marcela González-Gross, Anthony Kafatos, Odysseas Androutsos, Angela Polito, Dénes Molnar, Kurt Widhalm, Luis A Moreno
BACKGROUND: To examine the independent associations between physical activity (PA) intensities, sedentary time (ST), TV viewing, cardiorespiratory fitness (CRF) and muscular fitness (MF) with cardiovascular disease (CVD) risk in youth. METHODS: A cross-sectional study on 534 European adolescents (252 males, 282 females, 12.5-17.5years). Minutes per day of light (LPA), moderate (MPA) and vigorous (VPA) PA and total ST were measured using accelerometers. TV viewing time was measured using a questionnaire...
November 26, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29203211/qtc-interval-cardiovascular-events-and-mortality-in-patients-with-atrial-fibrillation
#12
Andreas Reusser, Steffen Blum, Stefanie Aeschbacher, Lucien Eggimann, Peter Ammann, Paul Erne, Giorgio Moschovitis, Marcello Di Valentino, Dipen Shah, Jürg Schläpfer, Samuel Manser, Tobias Reichlin, Michael Kühne, Christian Sticherling, Stefan Osswald, David Conen
BACKGROUND: A longer QTc interval has been associated with more adverse cardiovascular events and death in the general population. Little evidence is available on these relationships among patients with atrial fibrillation (AF). METHODS: We performed a prospective observational multicenter cohort study of 1413 patients with AF. A resting 12‑lead electrocardiogram (ECG) was performed at baseline. QT interval was corrected for heart rate using the Bazett formula (QTc)...
November 24, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29196090/diagnostic-performance-of-stress-perfusion-cardiac-magnetic-resonance-for-the-detection-of-coronary-artery-disease-a-systematic-review-and-meta-analysis
#13
Apostolos Kiaos, Ioannis Tziatzios, Stavros Hadjimiltiades, Charalambos Karvounis, Theodoros D Karamitsos
INTRODUCTION: The purpose of this study was to investigate the accuracy of qualitative stress perfusion cardiac magnetic resonance (CMR) to diagnose ischemia-causing lesions according to different definitions of significant coronary artery disease (CAD), and magnetic field strength. METHODS: We searched PubMed, Web of Science, and the Cochrane Library for studies evaluating diagnostic performance of qualitative stress perfusion CMR for diagnosis of CAD versus coronary angiography or fractional flow reserve (FFR) from inception to 10 September 2017...
November 24, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29180265/corrigendum-to-physiologic-mechanism-of-discordance-between-instantaneous-wave-free-ratio-and-fractional-flow-reserve-insight-from-13n-ammonium-positron-emission-tomography-int-j-cardiol-243-2017-91-94
#14
Joo Myung Lee, Doyeon Hwang, Jonghanne Park, Yaliang Tong, Bon-Kwon Koo
No abstract text is available yet for this article.
November 24, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29180268/takayasu-arteritis-in-young-women-with-acute-ischemic-heart-disease-time-to-shift-from-anecdote-to-clinical-practice
#15
EDITORIAL
Fulvio Salvo
No abstract text is available yet for this article.
November 23, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29180263/polypill-hypertension-and-medication-adherence-the-solution-strategy
#16
D Cimmaruta, N Lombardi, C Borghi, G Rosano, F Rossi, A Mugelli
INTRODUCTION: Hypertension is an important global health challenge and a leading preventable risk factor for premature death and disability worldwide. In current cardiology practice, the main obstacles in the management of patients affected by hypertension are comorbidities and poor adherence to pharmacological treatments. The World Health Organization has recently highlighted increased adherence as a key development need for reducing cardiovascular disease. METHODS: Principal observational and clinical trial data regarding adherence, reductions in cardiovascular risk and safety of the polypill approach are summarized and reviewed...
November 23, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29196089/atrial-fibrillation-ablation-with-the-second-generation-cryoballoon-multicenter-propensity-score-matched-comparison-between-freezing-strategies
#17
Erwin Ströker, Kaspars Kupics, Carlo de Asmundis, Giacomo Mugnai, Valentina de Regibus, Jeroen De Cocker, Dirk Stockman, Saverio Iacopino, Juan Sieira-Moret, Pedro Brugada, Bruno Schwagten, Yves De Greef, Gian-Battista Chierchia
BACKGROUND: Second generation cryoballoon (CB-A) ablation is highly effective in achieving pulmonary vein (PV) isolation and freedom from atrial fibrillation (AF). However, the ideal freezing strategy is still under debate. Our objective was to investigate the efficacy and outcome between different freezing strategies used with the CB-A in a multicenter, matched population. METHODS: From a total cohort of 1018 patients having undergone CB-A ablation for drug-refractory AF, 673 patients with follow-up ≥6months were included and stratified according to the applied freezing strategy: bonus freeze (BF) versus single freeze (SF)...
November 22, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29180266/heart-kidney-and-fgf23-les-liaisons-dangereuses
#18
EDITORIAL
Giuseppe Vergaro, Alberto Aimo, Claudio Passino, Michele Emdin
No abstract text is available yet for this article.
November 22, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29180264/impact-of-persistent-st-elevation-on-outcome-in-patients-with-takotsubo-syndrome-results-from-the-german-italian-stress-cardiomyopathy-geist-registry
#19
Francesco Santoro, Thomas Stiermaier, Nicola Tarantino, Francesca Guastafierro, Tobias Graf, Christian Möller, Luigi F M Di Martino, Holger Thiele, Matteo Di Biase, Ingo Eitel, Natale Daniele Brunetti
BACKGROUND: Potential predictors of clinical complications of Takotsubo syndrome (TTS) are poorly known. Persistent ST-segment elevation (PSTE) may have an impact on outcome similar as previously reported in acute coronary syndrome. The aim of this study was to assess the prevalence and prognostic relevance of PSTE in patients with TTS. METHODS: Two-hundred-sixty-nine consecutive patients were enrolled in an international multicenter registry. PSTE was defined as the documentation of ST-elevation at least for the first 48h of hospitalization...
November 22, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29196091/minimally-invasive-percutaneous-transluminal-renal-artery-stenting
#20
Ken Kongoji, Takanobu Mitarai, Mizuho Kasahara, Hiroshi Yamazaki, Yuki Ishibashi, Kohei Koyama, Kihei Yoneyama, Yasuhiro Tanabe, Yoshihiro J Akashi, Hideaki Yoshino
BACKGROUND: Minimally invasive percutaneous transluminal renal artery stenting (MIPTRS) is a method that prevents complications to the greatest extent possible. The present study aimed to investigate the safety and efficacy of MIPTRS performed in cases of renal artery stenosis with an estimated glomerular filtration rate (eGFR)≤45mL/min. METHODS: Cases of patients who underwent MIPTRS at our hospital between December 2010 and June 2015 in whom eGFR was ≤45mL/min were retrospectively analysed...
November 21, 2017: International Journal of Cardiology
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