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International Journal of Cardiology

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https://www.readbyqxmd.com/read/28222894/the-relationship-between-left-ventricular-deformation-and-heart-rate-variability-in-patients-with-systemic-sclerosis-two-and-three-dimensional-strain-analysis
#1
Marijana Tadic, Maja Zlatanovic, Cesare Cuspidi, Branislava Ivanovic, Ana Stevanovic, Nemanja Damjanov, Vesna Kocijancic, Vera Celic
OBJECTIVE: We sought to investigate left ventricular (LV) function and deformation, as well as heart rate variability (HRV), and their relationship, in patients with systemic sclerosis (SSc). METHODS: The study included 49 SSc patients and 38 age-matched healthy subjects. All patients underwent clinical examination, serological tests, 24-h Holter monitoring, and comprehensive two- and three-dimensional echocardiography (2DE and 3DE). RESULTS: 2DE and 3DE LV global longitudinal and circumferential strain, as well as 3DE area strains are significantly reduced in SSc patients comparing with controls...
February 14, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28215464/patients-with-intracranial-bleeding-and-atrial-fibrillation-treated-with-left-atrial-appendage-occlusion-results-from-the-amplatzer-cardiac-plug-registry
#2
Apostolos Tzikas, Xavier Freixa, Laura Llull, Sameer Gafoor, Samera Shakir, Heyder Omran, George Giannakoulas, Sergio Berti, Gennaro Santoro, Joelle Kefer, Adel Aminian, Steffen Gloekler, Ulf Landmesser, Jens Erik Nielsen-Kudsk, Ignacio Cruz-Gonzalez, Prapa Kanagaratnam, Fabian Nietlispach, Reda Ibrahim, Horst Sievert, Wolfgang Schillinger, Jai-Wun Park, Bernhard Meier, Haralampos Karvounis
BACKGROUND: In patients with non-valvular atrial fibrillation (NVAF), intracranial bleeding (ICB) constitutes a very challenging situation in which the rate of both ischemic and hemorrhagic events is increased. In these patients, left atrial appendage occlusion (LAAO) might represent a very valid alternative. OBJECTIVES: To investigate the procedural safety and long-term outcome of patients undergoing LAAO therapy due to previous ICB. METHODS: Data from the Amplatzer Cardiac Plug multicenter registry on 1047 consecutive patients were analyzed...
February 13, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28214080/clinical-outcome-and-correlates-of-coronary-microvascular-obstruction-in-latecomers-after-acute-myocardial-infarction
#3
Rocco A Montone, Giampaolo Niccoli, Silvia Minelli, Francesco Fracassi, Vincenzo Vetrugno, Cristina Aurigemma, Francesco Burzotta, Italo Porto, Carlo Trani, Filippo Crea
AIMS: Microvascular obstruction (MVO) is associated with a worse prognosis in patients with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PCI). However, data about incidence, clinical outcome and correlates of MVO in latecomers after STEMI are still lacking. METHODS: We prospectively enrolled consecutive patients that were latecomers after STEMI (symptoms onset >12h) undergoing PCI. We performed an angiographic analysis to assess the occurrence of MVO [defined as TIMI flow grade ≤2 or 3 with a myocardial blush grade <2]...
February 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28214079/postoperative-ischemic-stroke-and-death-prediction-with-cha2ds2-vasc-score-in-patients-having-coronary-artery-bypass-grafting-surgery-a-nationwide-cohort-study
#4
Wei-Syun Hu, Cheng-Li Lin
OBJECTIVES: This nationwide cohort study was attempted to address the predictive ability of CHA2DS2-VASc score in both ischemic stroke and death in patients undergoing coronary artery bypass grafting (CABG) surgery. METHODS: We identified patients aged ≥18years undergoing de novo CABG between January 1, 2000 and December 31, 2011. We calculated CHA2DS2-VASc score for each study patient. We used univariable and multivariable Cox proportional hazards regression models to measure the hazard ratios (HRs) and 95% confidence intervals (CIs) for ischemic stroke and death associated with CHA2DS2-VASc score in the study patients...
February 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28214078/the-optimize-heart-failure-care-program-initial-lessons-from-global-implementation
#5
Martin R Cowie, Yuri M Lopatin, Clara Saldarriaga, Cândida Fonseca, David Sim, Jose Antonio Magaña, Denilson Albuquerque, Marcelo Trivi, Gustavo Moncada, Baldomero A González Castillo, Mario Osvaldo Speranza Sánchez, Edward Chung
Hospitalization for heart failure (HF) places a major burden on healthcare services worldwide, and is a strong predictor of increased mortality especially in the first three months after discharge. Though undesirable, hospitalization is an opportunity to optimize HF therapy and advise clinicians and patients about the importance of continued adherence to HF medication and regular monitoring. The Optimize Heart Failure Care Program (www.optimize-hf.com), which has been implemented in 45 countries, is designed to improve outcomes following HF hospitalization through inexpensive initiatives to improve prescription of appropriate drug therapies, patient education and engagement, and post-discharge planning...
February 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28202260/allopurinol-benzbromarone-and-risk-of-coronary-heart-disease-in-gout-patients-a-population-based-study
#6
Hsiu-Chen Lin, Masao Daimon, Ching-Hung Wang, Yi Ho, Yow-Shieng Uang, Shuo-Ju Chiang, Li-Hsuan Wang
BACKGROUND: The effect of gout on the risk of developing coronary artery disease (CAD) is uncertain. Some studies have found that gout is a risk factor for acute myocardial infarction. This study examined the changes in risk of CAD in gout patients taking allopurinol and/or benzbromarone, and analyzed the dose-response relationship of both drugs with CAD incidence. METHODS: The medical records of one million subjects from 2000 to 2011 were provided by the Taiwan National Health Insurance Research Database...
February 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28215396/reply-to-the-letter-to-the-editor-make-surgery-proud-again
#7
LETTER
Hisato Takagi, Tomo Ando, Takuya Umemoto
No abstract text is available yet for this article.
February 11, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28215467/cardiovascular-screening-in-low-income-settings-using-a-novel-4-lead-smartphone-based-electrocardiograph-d-heart%C3%A2
#8
Niccolo' Maurizi, Alessandro Faragli, Jacopo Imberti, Nicolò Briante, Mattia Targetti, Katia Baldini, Amadou Sall, Abibou Cisse, Francesca Gigli Berzolari, Paola Borrelli, Fulvio Avvantaggiato, Stefano Perlini, Niccolo' Marchionni, Franco Cecchi, Gianbattista Parigi, Iacopo Olivotto
BACKGROUND: MHealth technologies are revolutionizing cardiovascular medicine. However, a low-cost, user-friendly smartphone-based electrocardiograph is still lacking. D-Heart® is a portable device that enables the acquisition of the ECG on multiple leads which streams via Bluetooth to any smartphone. Because of the potential impact of this technology in low-income settings, we determined the accuracy of D-Heart® tracings in the stratification of ECG morphological abnormalities, compared with 12-lead ECGs...
February 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28215466/the-prevalence-of-frailty-in-heart-failure-a-systematic-review-and-meta-analysis
#9
Quin E Denfeld, Kerri Winters-Stone, James O Mudd, Jill M Gelow, Sawsan Kurdi, Christopher S Lee
BACKGROUND: There is a growing interest in the intersection of heart failure (HF) and frailty; however, estimates of the prevalence of frailty in HF vary widely. The purpose of this paper was to quantitatively synthesize published literature on the prevalence of frailty in HF and to examine the relationship between study characteristics (i.e. age and functional class) and the prevalence of frailty in HF. METHODS: The prevalence of frailty in HF, divided into Physical Frailty and Multidimensional Frailty measures, was synthesized across published studies using a random-effects meta-analysis of proportions approach...
February 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28214082/effect-of-remote-ischemia-or-nicorandil-on-myocardial-injury-following-percutaneous-coronary-intervention-in-patients-with-stable-coronary-artery-disease-a-randomized-controlled-trial
#10
Toru Miyoshi, Kentaro Ejiri, Kunihisa Kohno, Makoto Nakahama, Masayuki Doi, Mitsuru Munemasa, Masaaki Murakami, Atsushi Takaishi, Yusuke Kawai, Tetsuya Sato, Katsumasa Sato, Takefumi Oka, Natsuki Takahashi, Satoru Sakuragi, Atsushi Mima, Kenki Enko, Shingo Hosogi, Seiji Nanba, Ryoichi Hirami, Kazufumi Nakamura, Hiroshi Ito
BACKGROUND: The effect of remote ischemic preconditioning (RIPC) and nicorandil on periprocedural myocardial injury (pMI) in patients with planned percutaneous coronary intervention (PCI) remains controversial. The aim of this randomized trial was to evaluate the effect of RIPC or nicorandil on pMI following PCI in patients with stable coronary artery disease (CAD) compared with a control group. METHODS: Patients with stable CAD who planned to undergo PCI were assigned to a 1:1:1 ratio to control, RIPC, or intravenous nicorandil (6mg/h)...
February 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28209387/associations-of-cardiovascular-and-all-cause-mortality-events-with-oxygen-uptake-at-ventilatory-threshold
#11
Setor K Kunutsor, Sudhir Kurl, Hassan Khan, Francesco Zaccardi, Jari A Laukkanen
BACKGROUND: Oxygen uptake (VO2) at ventilatory threshold (VT), is a cardiopulmonary exercise testing parameter which may be a proxy for peak VO2. We aimed to assess the associations of VO2 at VT with sudden cardiac death (SCD), fatal coronary heart disease (CHD) and cardiovascular disease (CVD), and all-cause mortality. METHODS AND RESULTS: VO2 at VT was assessed during a submaximal exercise test using respiratory gas analyzers in the Kuopio Ischemic Heart Disease cohort of 1639 middle-aged men...
February 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28215468/outcome-of-patients-undergoing-tavr-with-and-without-the-attendance-of-an-anesthesiologist
#12
Maayan Konigstein, Jeremy Ben-Shoshan, David Zahler, Nir Flint, Gilad Margolis, Yoav Granot, Galit Aviram, Amir Halkin, Gad Keren, Shmuel Banai, Ariel Finkelstein
BACKGROUND: During the last few years there is a shift from performing Transcatheter Aortic Valve Replacement (TAVR) under general anesthesia towards conscious sedation and local anesthesia only. In the vast majority of centers, sedation is guided by a qualified anesthesiologist. In our center, all TAVR procedures are being performed under local anesthesia and mild sedation, however, since September 2014, a large portion of TAVR procedures are being performed under local anesthesia without the presence of an anesthesiologist...
February 9, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28215465/the-frailty-syndrome-is-associated-with-adverse-health-outcomes-in-very-old-patients-with-stable-heart-failure-a-prospective-study-in-six-spanish-hospitals
#13
Carlos Rodríguez-Pascual, Emilio Paredes-Galán, Ana-Isabel Ferrero-Martínez, Jose-Luis Gonzalez-Guerrero, Mercedes Hornillos-Calvo, Rocio Menendez-Colino, Ivett Torres-Torres, Arturo Vilches-Moraga, Maria-Concepcion Galán, Francisco Suarez-Garcia, Maria-Teresa Olcoz-Chiva, Fernando Rodríguez-Artalejo
BACKGROUND: Most studies on the association between the frailty syndrome and adverse health outcomes in patients with heart failure (HF) have used non-standard definitions of frailty. This study examined the association of frailty, diagnosed by well-accepted criteria, with mortality, readmission and functional decline in very old ambulatory patients with HF. METHODS: Prospective study with 497 patients in six Spanish hospitals and followed up during one year. Mean (SD) age was 85...
February 8, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28202259/coronary-artery-calcium-score-as-a-predictor-for-incident-stroke-systematic-review-and-meta-analysis
#14
Kongkiat Chaikriangkrai, Hye Yeon Jhun, Ghanshyam Palamaner Subash Shantha, Aref Bin Abdulhak, Gardar Sigurdsson, Faisal Nabi, John J Mahmarian, Su Min Chang
BACKGROUND: Coronary artery calcium score (CACS) is a well-established test for risk stratifying asymptomatic patients for overall cardiovascular or coronary events. However; the prognostic value for incident stroke remains controversial. The objective of this study was to investigate the predictive value of CACS obtained by non-contrast electrocardiogram-gated computed tomography for incident stroke. METHODS: We searched PubMed, EMBASE, Cochrane databases for prospective longitudinal studies of CACS which reported the incidence of stroke...
February 8, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28190617/chronic-obstructive-pulmonary-disease-predicts-higher-incidence-and-in-hospital-mortality-for-atrial-fibrillation-an-observational-study-using-hospital-discharge-data-in-spain-2004-2013
#15
Manuel Méndez-Bailón, Ana Lopez-de-Andrés, Javier de Miguel-Diez, José Mª de Miguel-Yanes, Valentín Hernández-Barrera, Nuria Muñoz-Rivas, Noel Lorenzo-Villalba, Rodrigo Jiménez-García
BACKGROUND: Our objectives were to describe and compare trends in the incidence of hospitalization for atrial fibrillation (AF) in patients with and without chronic obstructive pulmonary disease (COPD) in Spain during 2004-2013 and to assess the effect of COPD on the in-hospital mortality (IHM) of patients with AF. METHODS: We performed a retrospective study using the Spanish National Hospital Discharge Database. The study population comprised patients≥40years with a primary diagnosis of AF...
February 7, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28190616/plasma-levels-of-vasostatin-1-a-chromogranin-a-fragment-are-associated-with-carotid-artery-maximum-stenosis-a-pilot-study
#16
Tiziana Bachetti, Alberto Ferrari Bardile, Teresa Lucia Aloi, Barbara Colombo, Emma Assi, Giuseppina Savino, Andrea Vercelli, Roberto Colombo, Angelo Corti
BACKGROUND: Chromogranin A (CgA), a circulating protein released by the neuroendocrine system, can regulate vascular physiology and angiogenesis. Full-length CgA (CgA1-439) and its fragment CgA1-76 (called vasostatin-1, VS-1) preserve the physiological integrity of the endothelial barrier function and are antiangiogenic, whereas CgA1-373 is proangiogenic. We investigated whether these polypeptides are altered in patients with various degrees of carotid artery atherosclerosis. METHODS: We studied 81 patients with carotid artery atherosclerosis, asymptomatic for cerebrovascular diseases...
February 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28209388/increased-risk-of-thromboembolic-events-in-adult-congenital-heart-disease-patients-with-atrial-tachyarrhythmias
#17
Keita Masuda, Tomoko Ishizu, Koichiro Niwa, Fumie Takechi, Shigeru Tateno, Hitoshi Horigome, Kazutaka Aonuma
BACKGROUND: Atrial tachyarrhythmias are a major morbidity in patients with adult congenital heart disease (ACHD). However, few studies have investigated risk stratification of thromboembolic events in ACHD patients with atrial tachyarrhythmias. METHODS AND RESULTS: This retrospective cohort study reviewed the clinical records of 2314 ACHD patients from 1977 to 2014. We found 242 (10.4%) patients with atrial tachyarrhythmias and excluded 84 patients already being treated with anticoagulant therapy...
February 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28188000/effectiveness-of-a-management-program-for-outpatient-clinic-or-remote-titration-of-beta-blockers-in-crt-patients-the-restore-study
#18
Antonio D'Onofrio, Pietro Palmisano, Antonio Rapacciuolo, Ernesto Ammendola, Leonardo Calò, Antonio Ruocco, Valter Bianchi, Fabio Maresca, Giuseppe Del Giorno, Annamaria Martino, Ciro Mauro, Monica Campari, Sergio Valsecchi, Michele Accogli
BACKGROUND: Many patients fail to receive β-blockers before cardiac resynchronization therapy defibrillator (CRT-D) implantation, or receive them at a suboptimal dose, and require optimization after implantation. We assessed the effectiveness of a structured program for β-blocker titration in CRT-D patients followed up by means of conventional in-clinic visits or remote monitoring. METHODS AND RESULTS: 130 patients undergoing CRT implantation and treated according to the standard practice of the centers were included as a control group...
February 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28185702/impact-of-total-arterial-revascularization-on-long-term-survival-a-systematic-review-and-meta-analysis-of-130-305-patients
#19
Bobby Yanagawa, Subodh Verma, Amine Mazine, Derrick Y Tam, Peter Jüni, John D Puskas, Shamini Murugavel, Jan O Friedrich
OBJECTIVES: This meta-analysis compares total arterial revascularization (TAR) versus conventional coronary artery bypass and additionally to two arterial grafts. METHODS: We searched MEDLINE and EMBASE Databases from 1996-to-2016 for studies comparing TAR versus non-TAR for multi-vessel surgical revascularization. Data were extracted by 2 independent investigators. Meta-analysis used random effects, which incorporates heterogeneity. RESULTS: There were 4 smaller shorter follow-up randomized controlled trials (RCTs), plus 15 matched/adjusted and 6 unmatched/unadjusted larger longer follow-up observational studies that met inclusion criteria (N=130...
February 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28202256/transseptal-puncture-review-of-anatomy-techniques-complications-and-challenges
#20
REVIEW
Barry O'Brien, Haroon Zafar, Simon De Freitas, Faisal Sharif
In recent years, the transseptal puncture approach has enabled passage of increasingly large and complex devices into the left atrium. Traditional tools remain effective in creating and dilating the initial puncture, with an acceptable safety profile. Even for skilled operators, the procedure is technically demanding and requires sound understanding of atrial anatomy. Intracardiac echocardiography is useful in cases of previous septal repair, poorly defined fossa ovalis anatomy or when considering patent foramen ovale portal crossing...
February 4, 2017: International Journal of Cardiology
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