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Journal of Psychoactive Drugs

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https://www.readbyqxmd.com/read/28594602/randomized-pilot-of-an-anxiety-sensitivity-based-intervention-for-individuals-in-a-substance-use-day-program
#1
Blaise L Worden, Marla Genova, David F Tolin
Anxiety sensitivity (AS), or the tendency to appraise physical symptoms as intolerable or dangerous, may maintain the cycle between co-occurring anxiety and substance use disorders. This study examined preliminary efficacy of a brief intervention targeting AS for individuals with heterogeneous substance use disorders. Forty-one patients with high AS entering an addictions day program were randomized to treatment as usual (TAU) or to TAU plus a nine-hour AS-focused intervention that consisted of interoceptive exposures, psychoeducation about the cycle of problematic substance use and anxiety, and a single session of cognitive challenging (e...
June 8, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28590798/beyond-ketamine-and-phencyclidine-analytically-confirmed-use-of-multiple-novel-arylcyclohexylamines
#2
Stephen Thornton, David Lisbon, Thomas Lin, Roy Gerona
BACKGROUND: Methoxetamine and 3-methoxy-phencyclidine are novel arylcyclohexylamines whose use and clinical toxicity are poorly reported in the medical literature. We report a case of analytically confirmed use of both methoxetamine and 3-methoxy-phencyclidine. CASE REPORT: A 27-year-old male presented 10 hours after insufflating an Internet-obtained powder. He was hypertensive, tachycardic, and demonstrated dissociated affect, a delayed verbal response to questions, ataxia, and vertical nystagmus...
June 7, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28569652/something-new-about-something-old-a-10-year-follow-up-on-classical-and-new-psychoactive-tryptamines-and-results-of-analysis
#3
Álvaro José Palma-Conesa, Mireia Ventura, Liliana Galindo, Francina Fonseca, Marc Grifell, Pol Quintana, Iván Fornís, Cristina Gil, Magí Farré, Marta Torrens
New psychoactive tryptamines may be a public health risk since they intend to mimic the hallucinogenic effects of regulated psychoactive drugs. Few studies describe uses and clinical effects of unregulated new psychoactive tryptamines. This study aims (1) to explore the presence of tryptamines classified as NPS among the substances delivered for analysis to a harm-reduction organization; (2) to describe the substances found in the samples after analysis; and (3) to compare analytical results of regulated vs...
June 1, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28557570/childhood-maltreatment-emotional-lability-and-alcohol-problems-in-young-adults-at-risk-for-adhd-testing-moderation-and-moderated-moderation
#4
Nóra Bunford, Brian T Wymbs, Anne E Dawson, Ryan C Shorey
Childhood maltreatment and alcohol problems are common among young adults with attention-deficit hyperactivity disorder (ADHD). However, little is known about the degree to which maltreatment and alcohol problems are associated; potential pertinent mediating or moderating mechanisms, such as emotional lability; and whether this association varies by sex. We examined, in a sample of adults at risk for ADHD (N = 122, 37% male), the association between childhood maltreatment and alcohol problems, whether emotional lability mediated or moderated this association, and whether either role of emotional lability differed between men and women...
May 30, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28548619/stages-of-change-model-has-limited-value-in-explaining-the-change-in-use-of-cannabis-among-adolescent-participants-in-an-efficacious-motivational-interviewing-intervention
#5
Hans B Dupont, Math J J M Candel, Paul Lemmens, Charles D Kaplan, Dike van de Mheen, Nanne K De Vries
Previously, a Dutch randomized controlled trial evaluating an intervention aimed at changing adolescents' cannabis use, called Moti-4, has shown its efficacy. A secondary analysis of the Moti-4 data investigated the process of change specified by the Stage of Change (SOC) model in cannabis use during the trial. Seventy-one Moti-4 participants and 60 controls were recruited for the study with a pre-test, post-test (T1), and six-month follow-up (T2). All participants showed signs of problematic cannabis use. No contribution of the Moti-4 intervention to a change in SOC between T1 and T2 was found...
May 26, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28535130/home-manufacture-of-drugs-an-online-investigation-and-a-toxicological-reality-check-of-online-discussions-on-drug-chemistry
#6
Evelyn Hearne, Emanuele Amorim Alves, Marie Claire Van Hout, Jean-Paul C Grund
Emerging trends in market dynamics and the use of new psychoactive substances are both a public health concern and a complex regulatory issue. One novel area of investigation is the availability of homemade opioids, amphetamines and dissociatives, and the potential fueling of interest in clandestine home manufacture of drugs via the Internet. We illustrate here how online communal folk pharmacology of homemade drugs on drug website forums may actually inform home manufacture practices or contribute to the reduction of harms associated with this practice...
May 23, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28524758/seeking-safety-group-therapy-for-co-occurring-substance-use-disorder-and-ptsd-among-transgender-women-living-with-hiv-a-pilot-study
#7
Susannah Empson, Yvette P Cuca, Jennifer Cocohoba, Carol Dawson-Rose, Katy Davis, Edward L Machtinger
Transgender women living with HIV experience high rates of substance use, violence, and post-traumatic stress disorder (PTSD). Seeking Safety is a manualized, present-focused, cognitive-behavioral therapy program designed to address co-occurring substance use and PTSD. Seeking Safety has evidence of efficacy in a variety of populations but had not been evaluated specifically with people living with HIV or transgender women. We pilot-tested a 12-session Seeking Safety program with a group of transgender women living with HIV who reported substance use and a history of violence...
May 19, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28481178/psilocybin-assisted-therapy-a-review-of-a-novel-treatment-for-psychiatric-disorders
#8
Kelan Thomas, Benjamin Malcolm, Dan Lastra
Recent research suggests that functional connectivity changes may be involved in the pathophysiology of psychiatric disorders. Hyperconnectivity in the default mode network has been associated with psychopathology, but psychedelic serotonin agonists like psilocybin may profoundly disrupt these dysfunctional neural network circuits and provide a novel treatment for psychiatric disorders. We have reviewed the current literature to investigate the efficacy and safety of psilocybin-assisted therapy for the treatment of psychiatric disorders...
May 8, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28443705/severity-of-withdrawal-symptoms-plasma-oxytocin-levels-and-treatment-outcome-in-heroin-users-undergoing-acute-withdrawal
#9
Kakia Nikolaou, Dorothea Kapoukranidou, Samuel Ndungu, Georgios Floros, Leda Kovatsi
Pre-clinical studies show that, following chronic opioid exposure, oxytocin neurons exhibit over-excitation upon withdrawal, causing an increase in oxytocin brain and plasma levels. Relevant clinical data on humans are scarce. This study investigates the opioid withdrawal stress effect on oxytocin plasma levels in humans. We evaluated 57 male chronic heroin users in a residential detoxification program. We determined plasma oxytocin levels by ELISA and measured the stress effects of withdrawal using the COWS scale for opioid withdrawal, the VAS scale for craving, and the Hamilton scales for anxiety and depression on the second day of admission...
April 26, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28443703/psychedelics-personality-and-political-perspectives
#10
Matthew M Nour, Lisa Evans, Robin L Carhart-Harris
The psychedelic experience (including psychedelic-induced ego dissolution) can effect lasting change in a person's attitudes and beliefs. Here, we aimed to investigate the association between naturalistic psychedelic use and personality, political perspectives, and nature relatedness using an anonymous internet survey. Participants (N = 893) provided information about their naturalistic psychedelic, cocaine, and alcohol use, and answered questions relating to personality traits of openness and conscientiousness (Ten-Item Personality Inventory), nature relatedness (Nature-Relatedness Scale), and political attitudes (one-item liberalism-conservatism measure and five-item libertarian-authoritarian measure)...
April 26, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28441106/jwh-122-consumption-adverse-effects-a-case-of-hallucinogen-persisting-perception-disorder-five-year-follow-up
#11
Maurizio Coppola, Raffaella Mondola
Synthetic cannabinoid receptor agonists are a heterogeneous group of psychotropic drugs functionally related to Δ9-tetrahydrocannabinol. These substances, marketed as cannabis substitutes, have been associated with numerous cases of severe intoxication and death across the world. In our article, we describe a case of hallucinogen persisting perception disorder developing in a natural cannabis user after consumption of JWH-122, a naphthoylindole largely used since 2010. Clinical symptomatology persisted for about four years and was alleviated through treatment with clonazepam...
April 25, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28406348/motivations-for-using-mdma-ecstasy-molly-among-african-americans-implications-for-prevention-and-harm-reduction-programs
#12
Khary K Rigg
Despite the growing popularity of MDMA (ecstasy/molly) among African Americans, their motives for using the drug are still largely unknown. The purpose of this study was to identify and describe the most salient motivations for using MDMA among this understudied population. In-depth interviews (n = 15) were conducted with a sample of African American young adults in Southwest Florida between August 2014 and November 2015. The primary motivations for using MDMA included: (1) altering the effects of marijuana and alcohol; (2) lasting longer sexually; (3) enhancing sexual pleasure; and (4) facilitating "freaky" sexual experiences...
April 13, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28574802/health-reform-and-the-substance-use-disorder-treatment-system-a-time-of-change
#13
H Westley Clark
No abstract text is available yet for this article.
April 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28426332/buprenorphine-treatment-and-patient-use-of-health-services-after-the-affordable-care-act-in-an-integrated-health-care-system
#14
Cynthia I Campbell, Sujaya Parthasarathy, Kelly C Young-Wolff, Derek D Satre
The Affordable Care Act (ACA) was expected to benefit patients with substance use disorders, including opioid use disorders (OUDs). This study examined buprenorphine use and health services utilization by patients with OUDs pre- and post-ACA in a large health care system. Using electronic health record data, we examined demographic and clinical characteristics (substance use, psychiatric and medical conditions) of two patient cohorts using buprenorphine: those newly enrolled in 2012 ("pre-ACA," N = 204) and in 2014 ("post-ACA," N = 258)...
April 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28406363/insurance-receipt-and-readiness-for-opportunities-under-the-affordable-care-act-a-national-survey-of-treatment-providers-for-substance-use-disorders
#15
Lydia Aletraris, Mary Bond Edmond, Paul M Roman
This study measures the readiness of substance use disorder (SUD) treatment to use opportunities under the Affordable Care Act by examining Medicaid and private insurance acceptance between 2011 and 2013, as well as center characteristics associated with acceptance. Data for this study were from a random sample of SUD treatment centers in the United States. Interviews were conducted on site and face to face, with administrative and clinical directors. We employed logistic regression analyses to examine Medicaid acceptance and private insurance acceptance...
April 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28350232/massachusetts-substance-use-disorder-treatment-organizations-perspectives-on-the-affordable-care-act-changes-in-payment-services-and-system-design
#16
Amity E Quinn, Maureen T Stewart, Mary Brolin, Constance M Horgan, Nancy E Lane
The Affordable Care Act (ACA) expanded insurance benefits and coverage for substance use disorder (SUD) treatment and encouraged delivery and payment reforms. Massachusetts passed a similar reform in 2006. This study aims to assess Massachusetts SUD treatment organizations' responses to the ACA. Organizational interviews addressing challenges of and responses to the ACA were conducted in person June-December 2014 with 31 leaders at 12 treatment organizations across Massachusetts. Many organizations were affiliated with medical or social services and offered a range of SUD services...
April 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28350229/commercial-health-plan-coverage-of-selected-treatments-for-opioid-use-disorders-from-2003-to-2014
#17
Sharon Reif, Timothy B Creedon, Constance M Horgan, Maureen T Stewart, Deborah W Garnick
Opioid use disorders (OUDs) are receiving significant attention in the U.S. as a public health crisis. Access to treatment for OUDs is essential and was expected to improve following implementation of the federal parity law and the Affordable Care Act. This study examines changes in coverage and management of treatments for OUDs (opioid treatment programs (OTPs) as a covered service benefit, buprenorphine as a pharmacy benefit) before, during, and after parity and ACA implementation. Data are from three rounds of a nationally representative survey conducted with commercial health plans regarding behavioral health services in benefit years 2003, 2010, and 2014...
April 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28350226/integration-of-care-in-the-implementation-of-the-affordable-care-act-changes-in-treatment-services-in-a-national-sample-of-centers-treating-substance-use-disorders
#18
Lydia Aletraris, Paul M Roman, Jana Pruett
This study examined patterns of medicalization in substance use disorder (SUD) that are aligned with the goals of the Affordable Care Act (ACA). Using a nationally representative sample of SUD treatment programs, we examined changes in several treatment domains. While observed changes were modest, they were in directions that support the thrust of the ACA. Specifically, we found an increase in the percentage of treatment referrals from other health care providers. We found an increase in the number of physicians for programs that did have a physician on staff, and an increase in counselors certified in treating alcohol and drug addiction...
April 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28306416/the-addiction-benefits-scorecard-a-framework-to-promote-health-insurer-accountability-and-support-consumer-engagement
#19
Itai Danovitch, David Kan
Health care insurance plans covering treatment for substance use disorders (SUD) offer a wide range of benefits. Distinctions between health plan benefits are confusing, and consumers making selections may not adequately understand the characteristics or significance of the choices they have. The California Society of Addiction Medicine sought to help consumers make informed decisions about plan selections by providing education on the standard of care for SUD and presenting findings from an expert analysis of selected health plans...
April 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28296625/a-social-work-response-to-the-affordable-care-act-prevention-and-early-intervention
#20
Matthew J Corrigan, Kathryn Krase, John Charles Reed
The Patient Protection and Affordable Care Act represents a reinvestment in primary care, with a focus on prevention of illness and remediation of the impacts of chronic diseases through a behavioral health framework. Licensed social work professionals, specifically those trained in behavioral health, are a natural fit to help implement these new approaches. Though there are many evidence-based interventions that will be helpful, two that come from the field of substance abuse ought to be specifically beneficial: SAMHSA's SBIRT Model and Motivational Interviewing, developed by Miller and Rollnick...
April 2017: Journal of Psychoactive Drugs
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