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Journal of Clinical Psychopharmacology

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https://www.readbyqxmd.com/read/29443709/general-information-on-clinical-psychopharmacology-in-china
#1
Yifeng Shen, Huafang Li
No abstract text is available yet for this article.
February 13, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29432331/evaluation-of-the-effect-of-fluvoxamine-in-patients-with-schizophrenia-under-risperidone-treatment-a-clinical-trial
#2
Alireza Haji Seyed Javadi, Ali Akbar Shafikhani, Seyed Mohsen Zamir, Zahra Farzane Khanshir
PURPOSE/BACKGROUND: The effectiveness of selective-serotonin reuptake inhibitors in the improvement of schizophrenia is a controversial issue. The aim of this study was to evaluate the effect of fluvoxamine on the symptoms of schizophrenia including positive and negative symptoms, cognitive impairment, and quality of life. METHODS/PROCEDURES: This clinical trial was performed on 68 patients with chronic schizophrenia, treated with risperidone at 22 Bahman Hospital of Qazvin, Iran during 2015 to 2016...
February 9, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29432330/a-case-of-acute-problem-gambling-associated-with-agomelatine
#3
Ranjit Menon, Lachlan Cribb, Jerome Sarris, Chee H Ng
No abstract text is available yet for this article.
February 9, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29424807/two-year-methylphenidate-treatment-of-mental-fatigue-and-cognitive-function-after-a-traumatic-brain-injury-a-clinical-prospective-study
#4
Birgitta Johansson, Anna-Pia Wentzel, Paulin Andréll, Lars Rönnbäck, Clas Mannheimer
No abstract text is available yet for this article.
February 8, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29424806/intravenous-ketamine-relieves-pain-and-depression-after-traumatic-suicide-attempts-a-case-series
#5
Nicholas Mischel, Christian Bjerre-Real, Jonathan Komisar, Brian Ginsberg, Steven T Szabo, Xavier PreudʼHomme
No abstract text is available yet for this article.
February 8, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29424805/effects-of-alcohol-on-the-pharmacokinetics-of-blonanserin-and-n-deethylated-blonanserin-in-healthy-chinese-subjects
#6
Shuhua Deng, Xiaojia Ni, Dewei Shang, Zhanzhang Wang, Ming Zhang, Jinqing Hu, Xiuqing Zhu, Haoyang Lu, Yuqing Chen, Yuefeng Zhang, Huan Peng, Yuguan Wen
PURPOSE/BACKGROUND: Blonanserin is a novel antipsychotic drug approved for the treatment of schizophrenia in East Asia. The main objective of the present study was to investigate the effect of alcohol on the pharmacokinetic properties of blonanserin and its metabolite N-deethyl blonanserin in healthy Chinese male subjects under fasting conditions. METHODS/PROCEDURES: The study was designed as a randomized, open-label, crossover clinical investigation in 10 male volunteers, each of whom received 2 treatments under fasted conditions: treatment A, blonanserin (8 mg) with water, and treatment B, blonanserin (8 mg) with alcohol (1 mL/kg)...
February 8, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29424804/no-effect-of-adjunctive-minocycline-treatment-on-body-metabolism-in-patients-with-schizophrenia
#7
Fang Liu, Liqin Xie, Bingkui Zhang, Ye Ruan, Yong Zeng, XiuFeng Xu, Jingping Zhao, Xiaoduo Fan
PURPOSE/BACKGROUND: This study examined the effect of adjunctive minocycline on body metabolism in risperidone-treated patients with schizophrenia. METHODS/PROCEDURES: Each subject had a Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition diagnosis of schizophrenia and had been on stable dose of risperidone for at least 4 weeks. In a 16-week randomized, double-blind, placebo-controlled study, subjects received either minocycline (200 mg/d) or placebo...
February 8, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29424803/clozapine-associated-with-microscopic-colitis-in-the-setting-of-biopsy-proven-celiac-disease
#8
Kelly Holz, Natalie A Martos, Russell L Margolis
No abstract text is available yet for this article.
February 8, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29424802/predictors-of-topiramate-tolerability-in-heavy-cannabis-using-adolescents-and-young-adults-a-secondary-analysis-of-a-randomized-double-blind-placebo-controlled-trial
#9
Joshua C Gray, Hayley Treloar Padovano, Stephanie E Wemm, Robert Miranda
PURPOSE/BACKGROUND: Cannabis is the most commonly abused illicit drug and accounts for the greatest number of adolescent substance abuse treatment admissions. Despite urgent need for effective interventions, the best available psychosocial treatment options yield only modest effects. Topiramate showed promise as an adjunctive pharmacotherapy to a psychosocial intervention for cannabis misuse among adolescents and young adults in a recent clinical trial, but it was not well tolerated. This study investigated associations between clinical characteristics and side effects and dropout among adolescents and young adults randomized to topiramate...
February 8, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29424801/a-case-of-nonfatal-torsade-de-pointes-associated-with-psychiatric-polypharmacy
#10
Jonathan F Lister, Amanda L Torbett, Cassandra D Benge, Jennifer R Bean
No abstract text is available yet for this article.
February 8, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29420358/cardiomyopathy-secondary-to-long-term-treatment-with-lithium-a-case-report-and-literature-review
#11
Ángela Sofía Rosero Enríquez, Alejandro Ballesteros Prados, Alexandru S Petcu
No abstract text is available yet for this article.
February 7, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29420357/acetyl-cholinesterase-inhibitors-and-cell-derived-peripheral-inflammatory-cytokines-in-early-stages-of-alzheimer-s-disease
#12
Nikolaos Kokras, Evangelia Stamouli, Ioannis Sotiropoulos, Everina A Katirtzoglou, Kostas T Siarkos, Georgia Dalagiorgou, Krystallenia I Alexandraki, Stavroula Coulocheri, Christina Piperi, Antonios M Politis
BACKGROUND: Clinical and preclinical studies firmly support the involvement of the inflammation in the pathogenesis of Alzheimer's disease (AD). Despite acetylcholinesterase inhibitors (AChEI) being widely used in AD patients, there is no conclusive evidence about their impact on the inflammatory response. METHODS: This study investigates peripheral proinflammatory cytokines (interferon gamma [IFN-γ], tumor necrosis factor alpha [TNF-α], and interleukins 1β [IL-1β] and 6 [IL-6]) by firstly comparing peripheral blood mononuclear cell (PBMC)-derived secretion in drug-naïve and AChEI-treated AD patients versus healthy controls...
February 7, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29394180/a-case-study-of-clozapine-and-cognition-friend-or-foe
#13
George Savulich, Gisela Mezquida, Samuel Atkinson, Miguel Bernardo, Emilio Fernandez-Egea
No abstract text is available yet for this article.
February 1, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29389779/trypophobia-associated-with-gabapentin-a-case-report
#14
Thalia K Robakis
No abstract text is available yet for this article.
February 1, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29389778/statistics-commentary-series-commentary-no-25-measuring-change
#15
David L Streiner
No abstract text is available yet for this article.
February 1, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29389777/aripiprazole-treatment-of-compulsive-behaviors-associated-with-methylphenidate-in-a-child-with-down-syndrome
#16
Merve Sertdemir, Ömer Faruk Akça
No abstract text is available yet for this article.
February 1, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29360652/hyperprolactinemic-galactorrhea-as-a-side-effect-of-aripiprazole-an-adolescent-case-aripiprazole-related-hyperprolactinemic-galactorrhea
#17
Serkan Gunes
No abstract text is available yet for this article.
January 23, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29360651/improving-the-clinical-pharmacologic-assessment-of-abuse-potential-part-2-optimizing-the-design-of-human-abuse-potential-studies
#18
Edward M Sellers
PURPOSE: This article discusses the conduct of a human abuse potential study as outlined in the Food and Drug Administration Final Guidance to Industry on Assessment of Abuse Potential. In addition, areas where alternative approaches should be considered are proposed. PROCEDURES: The design, end points, conduct, and interpretation of the human abuse potential study were reviewed, analyzed, and placed in the context of current scientific knowledge and best practices to mitigate regulatory risk and expedite drug development...
January 23, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29360650/exploring-nitrous-oxide-as-treatment-of-mood-disorders-basic-concepts
#19
Peter Nagele, Charles F Zorumski, Charles Conway
Nitrous oxide (laughing gas) has shown early promise as a rapidly acting antidepressant in patients with treatment-resistant major depression and is currently investigated in several clinical trials. Because nitrous oxide is rarely administered outside operating rooms or dental practices, most psychiatrists are not familiar with how nitrous oxide is administered in a medical setting and what regulations guide its use. The goal of this brief review was to educate psychiatrists about the basic concepts of nitrous oxide administration and pharmacology...
January 23, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29232312/improvement-of-smoking-abstinence-rates-with-increased-varenicline-dosage-a-propensity-score-matched-analysis
#20
Maher Karam-Hage, George Kypriotakis, Jason D Robinson, Charles E Green, Gurtej Mann, Vance Rabius, Rosario Wippold, Janice A Blalock, Elie Mouhayar, Jean Tayar, Patrick Chaftari, Paul M Cinciripini
PURPOSE/BACKGROUND: It is unclear whether increasing the dose of varenicline beyond the standard dose of 2 mg/d would improve smoking abstinence. METHODS: We examined the effect of 3 mg/d of varenicline on smoking abstinence among smokers who had reduced their smoking by 50% or more in response to 2 mg/d for at least 6 weeks but had not quit smoking. Of 2833 patients treated with varenicline, dosage of a subset of 73 smokers was increased to 3 mg/d after 6 weeks...
December 11, 2017: Journal of Clinical Psychopharmacology
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