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Journal of Clinical Psychopharmacology

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https://www.readbyqxmd.com/read/28514237/oral-ketamine-in-treatment-resistant-depression-a-clinical-effectiveness-case-series
#1
Maryam I Al Shirawi, Sidney H Kennedy, Keith T Ho, Roisin Byrne, Jonathan Downar
PURPOSE: The aim of the study was to assess the effectiveness, tolerability, and safety of oral ketamine as an antidepressant treatment in adults with treatment-resistant depression. METHODS: We reviewed retrospective data on 22 patients with treatment-resistant depression, who failed at least 3 adequate antidepressant treatment trials and 1 adequate trial of repetitive transcranial magnetic stimulation; subsequently, they received open-label treatment with oral ketamine, commenced at a dose of 50 mg every 3 days, titrated up by 25 mg every 3 days, according to response and tolerability...
May 17, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28492426/trichotillomania-in-attention-deficit-hyperactivity-disorder-under-methylphenidate-treatment
#2
Tayfun Kara, İsmail Akaltun
No abstract text is available yet for this article.
May 10, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28486258/placental-transfer-of-paliperidone-during-treatment-with-a-depot-formulation
#3
Raymond Binns, Sean J OʼHalloran, Stephanie Teoh, Kate Doherty, David A Joyce
No abstract text is available yet for this article.
May 8, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28481767/development-of-atrial-flutter-after-initiation-of-clozapine-and-successful-rechallenge-without-recurrence
#4
Matt Perdue, Tim Botello
No abstract text is available yet for this article.
May 5, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28481766/haloperidol-does-not-activate-thrombogenic-factors-in-older-nonpsychotic-hospitalized-patients
#5
Astrid M van Strien, Edmée J M Schrijver, Carolina Karen J P W Keijsers, Nathalie C Péquériaux, Prabath W B Nanayakkara, Hieronymus Jeroen J Derijks, Rob J van Marum
No abstract text is available yet for this article.
May 5, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28475521/loss-of-eyebrows-madarosis-after-use-of-long-acting-methylphenidate-case-report
#6
Çiğdem Yektaş, Nuran Demir Samurcu, Ali Evren Tufan
No abstract text is available yet for this article.
May 4, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28437295/clozapine-associated-agranulocytosis-treatment-with-granulocyte-colony-stimulating-factor-granulocyte-macrophage-colony-stimulating-factor-a-systematic-review
#7
John Lally, Steffi Malik, Eromona Whiskey, David M Taylor, Fiona P Gaughran, Amir Krivoy, Robert J Flanagan, Aleksandar Mijovic, James H MacCabe
PURPOSE/BACKGROUND: Clozapine is associated with hematological abnormalities, notably neutropenia, which may progress to agranulocytosis. Granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) have been used to reduce the frequency and duration of clozapine-associated neutropenia. This review aims to explore the use, efficacy, and tolerability of these cytokines in the treatment of clozapine-associated agranulocytosis. METHODS/PROCEDURES: We conducted a systematic review of published interventional and observational studies, case series, and case reports where G-CSF/GM-CSF was used to treat clozapine-associated agranulocytosis...
April 22, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28410348/editors-note-paper-selected-for-the-mitchell-b-balter-award-2016
#8
(no author information available yet)
No abstract text is available yet for this article.
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28383364/a-phase-3-multicenter-open-label-12-month-extension-safety-and-tolerability-trial-of-lisdexamfetamine-dimesylate-in-adults-with-binge-eating-disorder
#9
Maria Gasior, James Hudson, Javier Quintero, M Celeste Ferreira-Cornwell, Jana Radewonuk, Susan L McElroy
BACKGROUND: A 12-month, open-label extension study assessed the long-term safety and tolerability of lisdexamfetamine dimesylate (LDX) in adults with binge eating disorder (BED). METHODS: Adults (aged 18-55 y) with BED who completed 1 of 3 antecedent studies were enrolled in a 52-week, open-label extension study (dose optimization, 4 weeks [initial titration dose, 30-mg LDX; target doses, 50- or 70-mg LDX]; dose maintenance, 48 weeks). Safety evaluations included the occurrence of treatment-emergent adverse events (TEAEs), vital sign and weight assessments, and Columbia-Suicide Severity Rating Scale responses...
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28383363/cerebrovascular-cardiovascular-and-mortality-events-in-new-users-of-selective-serotonin-reuptake-inhibitors-and-serotonin-norepinephrine-reuptake-inhibitors-a-propensity-score-matched-population-based-study
#10
Christine Leong, Silvia Alessi-Severini, Murray W Enns, Yao Nie, Jitender Sareen, James Bolton, Heather J Prior, Dan Chateau
BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs) are widely prescribed for mood and anxiety disorders. However, it is not clear whether SNRIs are more strongly associated with cardiovascular and cerebrovascular events than SSRIs. METHODS: This was a propensity score-matched, population-based, cohort study of Manitobans who started an SSRI or SNRI between April 1, 1998, and March 31, 2014. The primary outcome was a composite of acute myocardial infarction (AMI), stroke, or cardiovascular-related hospitalization within 1 year of drug initiation...
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28383362/aripiprazole-once-monthly-in-the-treatment-of-acute-psychotic-episodes-in-schizophrenia-post-hoc-analysis-of-positive-and-negative-syndrome-scale-marder-factor-scores
#11
Zahinoor Ismail, Timothy Peters-Strickland, Maia Miguelez, Ross A Baker, Peter Hertel, Anna Eramo, Na Jin, Pamela Perry, Raymond Sanchez, Robert D McQuade, John M Kane
BACKGROUND: Long-acting injectable antipsychotics are treatment options for acute and long-term treatment of patients with schizophrenia. In a previously published 12-week randomized, double-blind, placebo-controlled clinical trial of patients with schizophrenia experiencing an acute psychotic episode, aripiprazole once-monthly 400 mg (AOM 400) produced significantly greater improvement than placebo on the primary endpoint, Positive and Negative Syndrome Scale (PANSS) total score at week 10...
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28383361/galactorrhea-after-selective-serotonin-reuptake-inhibitor-use-in-an-adolescent-girl-a-case-report
#12
Duygu Kaba, Özgür Öner
No abstract text is available yet for this article.
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28383360/is-ondansetron-augmentation-effective-in-obsessive-compulsive-disorder
#13
Bangalore G Kalyani, Aditya Hegde, Shyam Sundar Arumugham, Janardhanan C Narayanaswamy, Suresh Bada Math, Y C Janardhan Reddy
No abstract text is available yet for this article.
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28383359/amantadine-for-antipsychotic-related-weight-gain-meta-analysis-of-randomized-placebo-controlled-trials
#14
Wei Zheng, Shibin Wang, Gabor S Ungvari, Chee H Ng, Xin-Hu Yang, Yu-Hong Gu, Ming Li, Ying-Qiang Xiang, Yu-Tao Xiang
PURPOSE: Weight gain associated with antipsychotics in schizophrenia has been an ongoing concern. This meta-analysis examined the efficacy and safety of amantadine as an adjunctive treatment of weight gain in schizophrenia by systematically searching and analyzing randomized controlled trials (RCTs). RCTs comparing adjunctive amantadine with placebo in adult patients with schizophrenia were included in the meta-analysis. METHODS: Two independent investigators searched the literature and extracted data...
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28383358/movement-disorders-in-adults-with-intellectual-disability-and-behavioral-problems-associated-with-use-of-antipsychotics
#15
Pauline Helene Both, Dieuwertje Sophia Sonneveld, Sylvie Beumer, Sita Margaretha Agatha Bierma-Zeinstra, Dederieke Anne Maria Maes-Festen
No abstract text is available yet for this article.
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28353490/accuracy-of-clinician-assessments-of-medication-status-in-the-emergency-setting-a-comparison-of-clinician-assessment-of-antipsychotic-usage-and-plasma-level-determination
#16
Leonardo V Lopez, Atef Shaikh, Jonathan Merson, Jessica Greenberg, Raymond F Suckow, John M Kane
PURPOSE: The present study aimed to assess the level of agreement between clinicians' routine assessments of medication status and plasma levels of commonly prescribed antipsychotic medications in patients presenting to an emergency room with an exacerbation of psychosis. METHODS: We studied 105 patients presenting to an emergency room and admitted to an inpatient psychiatric unit with a diagnosis of schizophrenia, schizoaffective disorder, bipolar I disorder, or psychotic disorder not otherwise specified and a prior outpatient medication regimen including risperidone, olanzapine, quetiapine, aripiprazole, or paliperidone...
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28350574/recurrent-hyperammonemia-associated-with-olanzapine
#17
Yung-Fu Wu
No abstract text is available yet for this article.
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28350573/possible-clozapine-overdose-associated-thromboembolic-event
#18
Bryan Sackey, Lisa J Miller, Michael C Davis
No abstract text is available yet for this article.
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28350572/aripiprazole-lauroxil-pharmacokinetic-profile-of-this-long-acting-injectable-antipsychotic-in-persons-with-schizophrenia
#19
Marjie L Hard, Richard J Mills, Brian M Sadler, Ryan Z Turncliff, Leslie Citrome
BACKGROUND: Aripiprazole lauroxil is an extended-release prodrug of aripiprazole for intramuscular injection, approved for schizophrenia treatment. We developed a population pharmacokinetic (PopPK) model to characterize aripiprazole lauroxil PK and evaluate dosing scenarios likely to be encountered in clinical practice. METHODS: Data from 616 patients with schizophrenia, collected from 5 clinical studies, were used to construct the PopPK model. The model was subsequently used to evaluate various dose levels and frequency and the impact of dosing delay on aripiprazole concentrations...
June 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28338549/reply-to-comments-by-drs-glue-and-menkes
#20
Roger S McIntyre, Yena Lee
No abstract text is available yet for this article.
June 2017: Journal of Clinical Psychopharmacology
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