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Journal of Clinical Psychopharmacology

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https://www.readbyqxmd.com/read/29028689/effective-switch-from-clozapine-to-aripiprazole-in-treatment-resistant-schizophrenia-and-comorbid-alcohol-use-disorder
#1
Robert J Feeley, Bachaar Arnaout, Gihyun Yoon
No abstract text is available yet for this article.
October 12, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29028688/angioedema-associated-with-long-acting-injectable-paliperidone-palmitate-a-case-report
#2
Athanasia Papadopoulou, Kitsos Gkikas, Vasiliki Efstathiou, Ilias Gkikas, Styliani Kokoris, Vasiliki Lagari, Charalabos Papageorgiou, Athanasios Douzenis, Nikolaos Siafakas, Emmanouil N Rizos
No abstract text is available yet for this article.
October 12, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29016377/psychopharmacology-training-for-psychiatry-residents-a-pilot-iterative-quality-improvement-project
#3
Kamini Vasudev, Akshya Vasudev, Ira D Glick
No abstract text is available yet for this article.
October 9, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29016376/possible-psychosis-associated-with-buprenorphine-withdrawal
#4
Praveen Navkhare, Gurvinder Kalra, Sahoo Saddichha
No abstract text is available yet for this article.
October 9, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29016375/the-impact-of-medication-anticholinergic-burden-on-cognitive-performance-in-people-with-schizophrenia
#5
Mei San Ang, Nur Amirah Abdul Rashid, Max Lam, Attilio Rapisarda, Michael Kraus, Richard S E Keefe, Jimmy Lee
BACKGROUND: Cognitive deficits are prevalent in people with schizophrenia and associated with functional impairments. In addition to antipsychotics, pharmacotherapy in schizophrenia often includes other psychotropics, and some of these agents possess anticholinergic properties, which may impair cognition. The objective of this study was to explore the association between medication anticholinergic burden and cognition in schizophrenia. METHODS: Seven hundred five individuals with schizophrenia completed a neuropsychological battery comprising Judgment of Line Orientation Test, Wechsler Abbreviated Scale of Intelligence Matrix Reasoning, Continuous Performance Test-Identical Pairs Version, and the Brief Assessment of Cognition in Schizophrenia...
October 9, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28984747/thirty-versus-ten-day-diazepam-treatment-for-alcohol-detoxification-and-a-comparison-of-drinking-patterns-craving-and-anxiety-for-up-to-12-weeks-a-proof-of-concept-open-label-randomized-controlled-trial
#6
Nicolas Simioni, Julien Labreuche, Hélène Behal, Olivier Cottencin, Benjamin Rolland
PURPOSE: The aim of this study was to evaluate whether a prolonged detoxification treatment could decrease the relapse rate at 3 months after alcohol cessation in alcohol-dependent individuals through decreasing the levels of postdetoxification craving and anxiety. METHODS: Twenty-six adult patients with alcohol dependence (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision) who began an outpatient alcohol cessation program with an initial drinking goal of abstinence were enrolled in a 3-month, parallel, randomized (1:1 ratio), controlled, open-label, pilot trial...
October 3, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28984746/late-reduction-of-cocaine-cravings-in-a-randomized-double-blind-trial-of-aripiprazole-vs-perphenazine-in-schizophrenia-and-comorbid-cocaine-dependence
#7
Thomas Beresford, Jennifer Buchanan, Elizabeth Brie Thumm, Chad Emrick, David Weitzenkamp, Patrick J Ronan
PURPOSE: Co-occurring schizophrenia spectrum disorder and International Statistical Classification of Diseases, 10th Revision cocaine dependence present a particularly destructive constellation that is often difficult to treat. Both conditions raise dopamine transmission effects in the brain. Traditional neuroleptics block dopamine receptors, whereas aripiprazole modulates dopamine activity as an agonist/antagonist. We tested whether dopamine modulation is superior to dopamine blocking in dual-diagnosis patients...
October 3, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28945664/correlates-of-nonimprovement-to-pharmacotherapy-for-chronic-antidepressant-resistant-military-service-related-posttraumatic-stress-disorder-insights-from-the-veterans-affairs-cooperative-study-no-504
#8
Simon P Byrne, John H Krystal, Robert A Rosenheck, Jennier Vessicchio, Robert H Pietrzak
BACKGROUND: Posttraumatic stress disorder (PTSD) is a chronic and often difficult-to-treat condition that is prevalent among military veterans. First-line pharmacotherapy for this population typically involves antidepressants; however, veterans who do not improve are sometimes prescribed antipsychotics such as risperidone. A 2011 randomized controlled trial of adjunctive risperidone versus placebo for veterans with chronic, antidepressant-resistant, military service-related PTSD revealed no difference between groups...
September 22, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28930768/a-6-month-prospective-trial-of-a-personalized-behavioral-intervention-long-acting-injectable-antipsychotic-in-individuals-with-schizophrenia-at-risk-of-treatment-nonadherence-and-homelessness
#9
Martha Sajatovic, Luis F Ramirez, Edna Fuentes-Casiano, Jamie Cage, Curtis Tatsuoka, Michelle E Aebi, Ashley Bukach, Kristin A Cassidy, Jennifer B Levin
PURPOSE: Long-acting injectable antipsychotics (LAI) can optimize adherence for high-risk serious mental illness (SMI). This customized adherence-enhancement approach delivered by social worker interventionists was combined with LAI (CAE-L) of paliperidone palmitate for homeless, poorly adherent individuals with SMI. METHODS: This 6-month prospective, uncontrolled trial of CAE-L in 30 recently homeless individuals with SMI assessed adherence using the Tablets Routine Questionnaire, injection frequency, and SMI symptoms measured by the Positive and Negative Syndrome Scale, Brief Psychiatric Rating Scale, and Clinical Global Impressions...
September 19, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28926353/randomized-double-blind-placebo-and-active-comparator-controlled-crossover-study-evaluating-the-abuse-potential-of-the-antiepileptic-drug-lacosamide-in-healthy-recreational-drug-users
#10
Kerri A Schoedel, Jens-Otto Andreas, Pamela Doty, Klaus Eckhardt, Edward M Sellers
PURPOSE: This phase 1, randomized, double-blind, placebo- and active comparator-controlled crossover study assessed the abuse potential of the antiepileptic drug, lacosamide. METHODS: After a qualification phase, 38 healthy, recreational central nervous system-depressant users were randomized to treatment sequences comprising single oral therapeutic (200 mg) and supratherapeutic (800 mg) doses of lacosamide, alprazolam (1.5 and 3 mg), and placebo. Subjective effects were assessed for 24 hours following each dose using a range of scales, with a 5- to 9-day washout between treatments...
September 18, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28926352/zinc-l-carnosine-complex-polaprezinc-for-the-treatment-of-binge-eating-three-case-reports
#11
Kensaku Sakae, Hiroyuki Yanagisawa
No abstract text is available yet for this article.
September 18, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28926351/treatment-of-comorbid-bipolar-disorder-improves-disabilities-and-neuropsychological-functioning-in-digeorge-syndrome-a-case-report
#12
Léa C Perret, Marc-Antoine Lodovighi, Odile Perret, El Chérif Ibrahim, Nicole Philip, Jean-Michel Azorin, Raoul Belzeaux
No abstract text is available yet for this article.
September 18, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28926350/statistics-commentary-series-commentary-no-23-a-plague-of-decimals-why-too-much-precision-can-be-misleading
#13
David L Streiner
No abstract text is available yet for this article.
September 18, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28901991/dose-dependent-achilles-tendinopathy-in-a-patient-on-aripiprazole
#14
Arash Javanbakht, Victor Ajluni
No abstract text is available yet for this article.
September 10, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28891834/naltrexone-for-self-injury-in-borderline-personality-with-venlafaxine-associated-hyponatremia
#15
Benjamin DeLucia
No abstract text is available yet for this article.
September 7, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28891833/differences-in-antipsychotic-prescriptions-between-centers-in-young-outpatients-with-schizophrenia
#16
Mikkel Højlund, Povl Munk-Jørgensen
No abstract text is available yet for this article.
September 7, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28820746/no-effects-of-d-cycloserine-enhancement-in-exposure-with-response-prevention-therapy-in-panic-disorder-with-agoraphobia-a-double-blind-randomized-controlled-trial
#17
Mieke Klein Hofmeijer-Sevink, Puck Duits, Marleen M Rijkeboer, Adriaan W Hoogendoorn, Harold J van Megen, Nienke C Vulink, Damiaan A Denys, Marcel A van den Hout, Anton J van Balkom, Danielle C Cath
PURPOSE/BACKGROUND: D-cycloserine (DCS) is a partial N-methyl-D-aspartate receptor agonist that potentially augments response to exposure therapy in anxiety disorders by enhancing extinction learning. This randomized, double-blinded, placebo-controlled augmentation trial examined (1) the effectiveness of adding 125 mg of DCS to exposure therapy (before or directly after the first 6 treatment sessions) in patients with panic disorder with agoraphobia and (2) the effectiveness of DCS augmentation preceding exposure relative to DCS augmentation directly postexposure...
August 18, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28817489/the-use-of-granulocyte-colony-stimulating-factor-in-clozapine-rechallenge-a-systematic-review
#18
John Lally, Steffi Malik, Amir Krivoy, Eromona Whiskey, David M Taylor, Fiona P Gaughran, Robert J Flanagan, Aleksandar Mijovic, James H MacCabe
PURPOSE/BACKGROUND: Clozapine is associated with hematological abnormalities, with neutropenia and agranulocytosis of most concern. Granulocyte colony-stimulating factor (G-CSF) has been used to support clozapine rechallenge after neutropenia with the aim of maintaining the neutrophil count. This study aims to explore the practice, use, safety, and efficacy of G-CSF in this context. METHODS/PROCEDURES: We conducted a systematic review to identify all studies investigating or describing G-CSF as a prophylaxis to enable continued clozapine treatment during a rechallenge...
August 16, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28817488/risk-management-of-hospitalized-psychiatric-patients-taking-multiple-qtc-prolonging-drugs
#19
Eline Vandael, Bert Vandenberk, Rik Willems, Johan Reyntens, Joris Vandenberghe, Veerle Foulon
PURPOSE/BACKGROUND: Drug-related QTc prolongation has been linked with Torsade de Pointes and sudden cardiac death. The objective of this study was to investigate the impact of starting an additional QTc-prolonging drug on the QTc interval of psychiatric inpatients. METHODS: An observational study was performed between May 2011 and December 2014 in 6 Belgian psychiatric hospitals. Inpatients who were already taking 1 QTc-prolonging drug or more could be included in the study when an additional QTc-prolonging drug was started...
August 16, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28816924/treatment-of-premenstrual-breakthrough-of-depression-with-adjunctive-oral-contraceptive-pills-compared-with-placebo
#20
Whitney Peters, Marlene P Freeman, Semmie Kim, Lee S Cohen, Hadine Joffe
PURPOSE/BACKGROUND: Two-thirds of women with depressive disorders report reemergence of depression premenstrually, or premenstrual exacerbation (PME), despite effective treatment of the underlying mood disorder during the remainder of the cycle. There is a paucity of studies that rigorously assess treatments targeting PME. Open-label data suggest that augmentation of antidepressants with the oral contraceptive pill (OCP) drospirenone and ethinyl estradiol (DRSP/EE) improves depressive symptoms that break through treatment premenstrually...
August 15, 2017: Journal of Clinical Psychopharmacology
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