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American Journal of Forensic Medicine and Pathology

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https://www.readbyqxmd.com/read/28230653/suicides-by-jumping-off-istanbul-bridges-linking-asia-and-europe
#1
Ayşe Yurtseven, İbrahim Üzün, Murat Nihat Arslan
AIM: The aim of this study was to determine the injury spectrum and characteristics of people who committed suicide by jumping into water from the July 15th Martyrs Bridge and Fatih Sultan Mehmet Bridges in Istanbul, Turkey. METHODS: This study included all of the jumpers from the July 15th Martyrs Bridge and Fatih Sultan Mehmet Bridge who were autopsied by the Council of Forensic Medicine, Istanbul Morgue Department, between 2000 and 2013. All of the data were collected from archived case files...
February 23, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28230652/a-case-of-postmortem-canine-depredation
#2
Dennis J Chute, Robert J Bready
We report the case of postmortem animal depredation that produced initial confusion for investigators who responded to the scene. A decomposing elderly woman was found in her presumed home with bilateral upper extremity amputations and craniocerebral trauma. This raised suspicion of foul play. Subsequent investigations together with autopsy led the medical examiner to conclude that the cause of death was natural disease and that those injuries found on her body were produced by at least one of the dogs who shared the premises...
February 23, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28114174/case-report-lightning-induced-pneumomediastinum
#3
Ryan Blumenthal, Gert Saayman
We present the case of a 41-year-old woman who was fatally injured during a witnessed lightning strike event and in whom autopsy revealed the unusual keraunopathological finding of overt pneumomediastinum. The possible pathophysiological mechanism(s) of causation of this phenomenon are discussed, with specific reference also to the "Macklin" effect and the role of blast overpressures associated with lightning strike. It is suggested that the latter may lead to sudden alveolar rupture, with subsequent rapid tracking of air along bronchovascular sheaths in a centripetal manner toward the hilum of the lung and thus into the mediastinum...
January 21, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28106684/sudden-death-due-to-unusual-complication-of-takayasu-arteritis-an-autopsy-case
#4
Maher Jedidi, Youssef Chkirbene, Nihed Abdessayed, Tasnim Masmoudi, Mohamed Mahjoub, Souheil Mlayeh, Mohamed Ben Dhiab, Mohamed Kamel Souguir, Mohamed Taher Yacoubi
Takayasu arteritis is an uncommon inflammatory disease with usually a good prognosis. However, sometimes, the evolution can be fatal essentially by a coronary arteries involvement. We present a case of a 19-year-old woman who died suddenly from cardiogenic shock complicating an unknown Takayasu arteritis.At the autopsy, the aorta showed a significant thickening of the wall. The coronary arteries were slightly thickened and did not show any occlusion. Microscopic examination of the aorta showed an abundant granulomatous and a lymphoplasmacytic infiltrate...
January 18, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28085681/basal-ganglion-hemorrhage-as-delayed-complication-of-diethylene-glycol-ingestion
#5
Avneesh Gupta, Francisco J Diaz, Anita Lal, Lokman Sung, Cynthia K Aaron
Diethylene glycol (DEG), an organic compound (HOCH2CH2)2O is a commonly used solvent. Mass poisoning outbreaks have been reported because of frequent contaminations. A PubMed search for diethylene resulted in 795 publications with 151 specifically discussing the toxicity. Of the 151 reported toxicity reviews/case reports, only 6 publications discussed the long-term neurological effects of diethylene toxicity. We report a fatal case of oral ingestion of DEG with complications from delayed toxicity. She died 7 days after the second admission...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28079530/can-intoxication-status-be-used-as-a-prediction-tool-for-manner-of-death-a-comparison-of-the-intoxication-status-in-violent-suicides-and-homicides
#6
D Kimberley Molina, Veronica M Hargrove
Determining the manner of death in medicolegal death investigations can be difficult. The investigator relies on many facets of death investigation, including the circumstances of death and autopsy examination. A study was designed to analyze whether the intoxication status of the decedent could be used as another tool in death investigations. The intoxication status of violent (nonoverdose or poisoning) suicides and homicides was retrospectively reviewed and compared. A total of 625 deaths were identified, including 366 suicides and 259 homicides...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28072596/expression-of-glucose-regulated-protein-78-and-mir-199a-in-rat-brain-after-fatal-ligature-strangulation
#7
Xueying Feng, Dongchuan Zhang, Qingjin Gong, Zhiyong Zhang, Li Quan
The roles of endoplasmic reticulum (ER) stress and microRNA in the brain tissue after fatal mechanical asphyxia have not been clearly elucidated. We examined the expression of glucose-regulated protein 78 (GRP78), the key regulator of unfolded protein response, and miR-199a in the brain tissues of rats subjected to fatal ligature strangulation to understand the roles of ER stress and microRNA in ligature strangulation. The expressions of GRP78 and miR-199a in rat cortex, hippocampi, and midbrain were measured by immunohistochemistry and Western blot analysis in a rat model of ligature strangulation...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28067671/a-fatal-case-of-coin-battery-ingestion-in-an-18-month-old-child-case-report-and-literature-review
#8
Francesco Ventura, Sara Candosin, Rosario Barranco, Alessandro Bonsignore, Luisa Andrello, Luca Tajana, Antonio Osculati
The ingestion of extraneous substances is quite common in clinical practice; it usually befalls in the pediatric age, mostly between 6 months and 6 years. In most cases, complications do not emerge, and the prognosis is considered favorable. However, when a case of battery ingestion occurs, serious adverse events may develop. The ingestion of these components is a potential life-threatening event for children.In this article, we report the case of an 18-month-old child who died from hemorrhagic shock due to an aortoesophageal fistula caused by a 20 mm lithium button battery lodged in the esophagus...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28045743/role-of-survival-time-and-injury-severity-in-fatal-pulmonary-fat-embolism
#9
Juliane Jarmer, Garyfalia Ampanozi, Michael J Thali, Stephan A Bolliger
Pulmonary fat embolism (PFE) is frequent in blunt trauma and may occasionally lead to death. A correlation between fracture grade and severity and PFE grade has been described before, but no correlation between PFE and survival time, fat crushing extent, fat crush grade, or number of body regions with fractures could be noted in this small study. To further examine this, we decided to examine the aforementioned points in a far larger study group.Autopsy protocols of 188 nonresuscitated fatalities with blunt trauma and without right heart injury, which underwent whole body dissection, were retrospectively reviewed concerning the presence and the severity of PFE, injuries, survival time, age, sex, and the body mass index...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28045696/sudden-death-in-a-male-infant-due-to-histiocytoid-cardiomyopathy-an-autopsy-case-and-review-of-the-literature
#10
Hanbing Xie, Xueqin Chen, Ni Chen, Qiao Zhou
Histiocytoid cardiomyopathy (HC) is a very rare cardiac disorder that mainly affects female infants younger than 2 years. It may manifest as ventricular tachycardia or dilated cardiomyopathy and frequently causes sudden death. The most common grossly change is multifocal uneven thickening of the endocardium, presenting a yellowish color, with some area forming nodular appearance, and histologically featured by scattered clusters of histiocytoid myocytes under the endocardium. Here, we present a 19-month-old male infant who died of heart failure, and an autopsy was performed and confirmed the diagnosis of HC...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28045695/manner-of-death-determination-in-fire-fatalities-5-year-autopsy-data-of-istanbul-city
#11
İpek Esen Melez, Murat Nihat Arslan, Deniz Oguzhan Melez, Ahmet Selçuk Gürler, Yalçin Büyük
Death resulting from burns is an important social problem and a frequent accident. However, because approximately 10% of cases are estimated to result from a fire that was deliberately started, all fire-related deaths should be treated as suspicious, and the cause of a fire should be investigated. For the bodies recovered from the scene of a fire, the manner of death could also be suicide or homicide. The objective of this study was to contribute to the clarification of controversial data present in the literature on the manner of death determination of fire-related deaths, through evaluation of autopsy findings of bodies recovered from fires...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28045694/forensic-analysis-of-parachute-deaths
#12
Michael Philip Burke, Johannes Chitty
Deaths associated with parachuting are very uncommon. However, these deaths do tend to be "high profile" in the traditional and social media. When forensic pathologists examine the deceased after a fatal parachuting incident, the anatomical cause of death is usually not in question. For most forensic pathologists, it is usually the case that we will have very limited knowledge of parachuting equipment or the mechanics of a typical successful parachute jump. As such, the investigation of the death should involve a multidisciplinary approach with an appropriate expert providing the formal forensic examination of the parachuting equipment...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28009598/streptococcus-pneumoniae-detection-long-time-after-death-in-a-fatal-case-of-waterhouse-friderichsen-syndrome
#13
Andrea Verzeletti, Carlo Bonfanti, Anna Leide, Elena Azzalini, Maria Antonia De Francesco, Giorgio Piccinelli, Francesco De Ferrari
We report a fatal case of Waterhouse-Friderichsen syndrome in a 64-year-old man. The diagnosis, suspected during the autopsy (performed 63 hours after death), was confirmed through the successful detection of Streptococcus pneumoniae DNA and antigens in samples (blood and liver) collected during the autopsy. These results conformed with blood cultures performed antemortem, which became available only the day after the autopsy. The case underlines the need to collect biological material (liver and blood samples) during autopsy for microbiological investigations, although the collection is performed a long time after the death, suggesting that a liver sample works for DNA and liver and blood work for Streptococcus pneumoniae antigen detection...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28005586/sudden-death-from-ruptured-intracranial-vascular-malformations-during-mechanical-asphyxia-a-domestic-violence-case-report
#14
Xue-Mei Wu, Xu-Dong Zhang, Li-Bing Yun, Min Liu, Xu-Fu Yi
Smothering and manual strangulation are not uncommon in domestic violence against women; however, no report on the combination of mechanical asphyxia and intracranial vascular malformations has been previously published. We report a middle-aged woman who was smothered and manually strangled by her husband and subsequently died from subarachnoid hemorrhage due to ruptured intracranial vascular malformations, rather than direct mechanical asphyxiation. Smothering and manual strangulation are considered provocative conditions for rupture and contributory causes of death...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28005585/penicillin-induced-fulminant-myocarditis-a-case-report-and-review-of-the-literature
#15
Mehdi Ben Khelil, Youssef Chkirbene, Mona Mlika, Slim Haouet, Moncef Hamdoun
Drug-induced eosinophilic myocarditis is uncommon with few cases reported in the literature. It is a rare but potentially life-threatening disease.We report the case of an 11-year-old girl without medical history who developed an acute malaise and chills, followed by severe shortness of breath and a cardiopulmonary arrest 1 hour after an intramuscular injection of penicillin.At autopsy, we observed in the external examination nonspecific asphyxia signs, an injection mark, and the absence of traumatic signs...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28005584/postmortem-increase-in-body-core-temperature-how-inaccurate-we-can-be-in-time-since-death-calculations
#16
Tomáš Vojtíšek, Štěpánka Kučerová, Jan Krajsa, Bülent Eren, Petra Vysočanová, Petr Hejna
Postmortem increase in body core temperature is a well-known phenomenon in forensic practice. Despite this, cases of reliably documented postmortem hyperthermia are rarely reported in the forensic literature, and it is still not clear how frequently postmortem hyperthermia occurs and in which cases we may it predict. In routine forensic practice, the standard course of body cooling is expected, and the prediction of normal body core temperature in the time of death is used for back-calculating the time of death by Henssge method...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28005583/the-virtual-hydrostatic-test
#17
Edward L Mazuchowski, Dori M Franco, Philip J Berran, H Theodore Harcke
The hydrostatic test is used to help determine if there has been a live birth. Computed tomography (CT), with its ability to detect and localize air/gas in the body, offers a rapid, noninvasive tool for assessment.Four baby deaths (20 to 25 weeks' gestation) in which the hydrostatic test, radiographs, and CT were performed before autopsy are presented. In 2 cases, considered stillbirths, the lungs and liver sank, and there was no air seen in the lungs or gas in the liver on CT. Histology of the lungs showed collapsed alveoli...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28002071/occupational-hydrogen-sulfide-fatalities-and-thiosulfate-levels
#18
Stephanie Sayre Smith, Dawn L Cannon, Kathleen Fagan, Christopher P Weis
No abstract text is available yet for this article.
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/27973393/sudden-cardiac-death-autopsy-findings-in-7200-cases-between-2001-and-2015
#19
Petru Ifteni, Barna Barabas, Claudia Gavris, Marius Moga, Victoria Burtea, Laura Dracea
BACKGROUND: Sudden cardiac death (SCD) is a sudden unexpected event, from a cardiac cause, that occurs in less than 1 hour after the symptom onset in a person without any previous condition that would seem fatal or who was seen without any symptoms 24 hours before being found dead. OBJECTIVE: The aims of the study were to describe the features of SCD in Brasov County, Romania (400,000 inhabitants) according to local forensic department autopsy files. METHODS: We retrospectively chart reviewed a number of 7200 autopsy reports between 2001 and 2015 to identify cases of SCD...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/27906701/child-sexual-abuse-confirmed-by-forensic-examination-in-salvador-bahia-brazil
#20
Welington Dos Santos Silva, Ubirajara de Oliveira Barroso-Junior
Child sexual abuse is a worldwide public health issue. The objective of this study was to describe the demographic and clinical characteristics of children in cases of sexual abuse confirmed by material evidence at forensic examination. Cases of children younger than 12 years examined for suspected sexual abuse at the Institute of Forensic Medicine in Salvador, Bahia, Brazil, were reviewed retrospectively. The period evaluated was between 2005 and 2010. The inclusion criterion was the coroner's confirmation of sexual abuse based on material evidence...
March 2017: American Journal of Forensic Medicine and Pathology
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