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American Journal of Forensic Medicine and Pathology

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https://www.readbyqxmd.com/read/28795995/toxic-myocarditis-caused-by-acetaminophen-in-a-multidrug-overdose
#1
Maxime Gosselin, Yann Dazé, Pascal Mireault, Marie Crahes
We report the case of an 18-year-old woman with personality disorders who was hospitalized a few hours after suicidal ingestion of acetaminophen, quetiapine, acetylsalicylic acid, and ethanol. Twelve hours after admission, severe liver damage was evident, but the patient was stable and awaiting hepatic transplantation. Electrolytes were successfully controlled. The condition of the liver stabilized. Cardiac biomarkers then deteriorated unexpectedly. Localized ST-segment elevations were noted on electrocardiogram, but angiography ruled out myocardial infarction...
August 9, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28796650/using-skin-gene-markers-for-estimating-early-postmortem-interval-at-different-temperatures
#2
Mona Mohamed Ali, Samah Fathy Ibrahim, Amel Ahmed Fayed
Many researches document long-term RNA persistence in a variety of tissues and its applicability in estimating the postmortem interval (PMI). Skin-specific mRNA marker, late cornified envelope 1C (LCE1C), was used to identified skin samples. Before using the LCE1C in criminal casework, its persistence and applicability for estimating PMI in different temperatures were tested. Twelve skin samples were collected from 6 patients, and 6 samples were kept at 24°C and others were kept at 40°C for 5 days. The expression levels of LCE1C mRNA are serially detected and quantified using real-time polymerase chain reaction...
August 8, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28767539/medicolegal-investigations-into-deaths-due-to-crush-asphyxia-after-tractor-side-rollovers
#3
Carlo Moreschi, Ugo Da Broi, Antonia Fanzutto, Sirio Cividino, Rino Gubiani, Gianfranco Pergher
Farm tractors are large, heavy, powerful vehicles with a high center of gravity. When driven carelessly on sloping, irregular, or slippery ground, tractors can overturn sideways and cause the death by crush asphyxia of the driver or passengers, especially if appropriate safety equipment is not fitted or used. The aim of this review is to focus on the diagnostic difficulties with which coroners and forensic pathologists have to cope when a confirmation of crush asphyxia after tractor side rollover is required by judicial authorities...
August 1, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28767538/two-fatal-intoxications-due-to-tramadol-alone-autopsy-case-reports-and-review-of-the-literature
#4
Sara Gioia, Massimo Lancia, Mauro Bacci, Fabio Suadoni
Since tramadol was marketed, it has been widely prescribed as a pain killer because of its relatively safe profile among opioids.Nevertheless, intoxication can occur: overdose can lead to fatal outcomes mostly in association with other drugs, via the potential interaction with serotonergic antidepressant medications, as well as the potential for increased central nervous system (CNS) depression.Fatal outcomes only attributable to tramadol are a rare entity. In this case report, 2 fatal cases are described due to tramadol stand-alone intoxication with peculiar characteristics...
August 1, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28737525/death-by-snow-a-fatal-forensic-case-of-cocaine-leakage-in-a-drug-mule-on-postmortem-computed-and-magnetic-resonance-tomography-compared-with-autopsy
#5
Patricia Mildred Flach, Dominic Gascho, René Fader, Rosita Martinez, Michael J Thali, Lars C Ebert
This forensic case presents unique postmortem imaging of a "drug mule" with fatal intoxication due to cocaine leakage on postmortem computed and magnetic resonance (MR) tomography compared with autopsy.Imaging by postmortem computed and MR tomography was performed before autopsy, histology, and toxicology were commissioned. Forensic imaging revealed 91 hyperdense, uniformly shaped body packs with signs of leakage, which was confirmed by autopsy. Postmortem MR imaging displayed the rarely described hypointense appearance of the body packs in T1- and T2-weighted sequences...
July 22, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28719379/critical-evaluation-of-metallization-in-electric-injury
#6
Sigitas Laima, Jana Bytautaite, Sigitas Chmieliauskas, Dmitrij Fomin, Algimantas Jasulaitis, Arturas Jukna, Sandra Mazeikiene, Jurgita Stasiuniene
The article presents 3 forensic medicine cases in the field of electric injury. In addition to traditional findings in electric injury (electric mark and histological findings), the forensic medicine experts in Lithuania also perform an atomic absorption spectrometry analysis. This method confirms the effects of electric current to the body through the electric conductor. Typical macroscopic finding in the skin is electric mark. Histologically, the damaged skin possesses characteristic features of thermal burns...
July 18, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28704207/the-adult-male-rape-victim-forensic-description-of-a-series-of-57-cases
#7
Michelangelo Bruno Casali, Elisa Palazzo, Alberto Blandino, Alessio Battistini, Francesca Motta, Alessandra Kustermann, Cristina Cattaneo
A retrospective analysis on 57 adult male victims of sexual violence has been performed. Age, nationality and anamnesis of the victims, location of the assault, type of violence, number and identity of the assailants, presence of physical injuries, lapse of time between the assault and the request of medical assistance, and toxicological and semen detection tests were analyzed. Victims were mostly in the 31- to 40-year age group. Ten victims referred themselves as either active homosexuals or bisexuals. Forced oral and/or anal penetration was registered in 86...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28692479/association-of-waist-hip-ratio-to-sudden-cardiac-death-and-severe-coronary-atherosclerosis-in-medicolegal-autopsies
#8
Linda Kocovski, Joshua Dogyeong Lee, Sameer Parpia, John Fernandes, Vidhya Nair
Various modifiable and nonmodifiable risk factors, such as abdominal obesity, are known to affect the development of atherosclerotic cardiovascular disease and subsequent sudden cardiac death (SCD). The waist-hip ratio is a surrogate marker of visceral obesity that has been shown in various studies to be a better predictor of cardiovascular risk than the body mass index (BMI), a measurement of generalized obesity. Waist-hip ratio was measured prospectively on medicolegal autopsies performed for 1 year, in addition to standard measurements of BMI and heart weight, and histologic determination of severe coronary atherosclerosis (SCA, coronary artery diameter stenosis >75%)...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28692478/diagnosis-of-vitality-in-skin-wounds-in-the-ligature-marks-resulting-from-suicide-hanging
#9
Isabel Legaz Pérez, Maria Falcón, M Gimenez, F Martínez Diaz, M D Pérez-Cárceles, E Osuna, D Nuno-Vieira, A Luna
Ascertaining the vital origin of skin wounds is one of the most challenging problems in forensic pathology. The forensic literature describes biomarkers and methods for differentiating vital and postmortem wounds, although no clear conclusions have been reached. The aim of this study was to characterize human vital wounds by analyzing the concentrations of metallic ions and the expression of P-selectin and cathepsin D in skin wounds in the ligature marks in a cohort of suicidal hangings for which vitality was previously demonstrated...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28691951/fatal-self-poisoning-with-massive-propranolol-ingestion-in-a-young-male-physician
#10
Supawon Srettabunjong
Suicidal intoxication from massive propranolol ingestion is rare. Surprisingly, no reported cases have involved physicians. The author herein reports a case of self-poisoning death due to ingestion of propranolol by a young male physician. A 31-year-old man with major depressive disorder was found dead in his dormitory room. Fifteen empty packages, each having contained ten 40-mg propranolol tablets, were found without any tablets leftover in his room. A suicide note was also found in his room. He was thus alleged to have ingested 6 g of propranolol for self-poisoning...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28691950/posttraumatic-stress-and-burnout-symptoms-in-forensic-doctors-and-staff-in-a-mortuary
#11
İlhami Kömür, Rifat O Ozdemirel, İsmail Ozver, Bünyamin Başpinar, Muhammet Demir, Fatih Gönen, Eyüp Kandemir, Murat Emul
We aimed to investigate burnout and posttraumatic stress symptoms in mortuary staff members who work for the Council of Forensic Medicine where more than 4500 autopsies are annually performed.The data were collected from 142 mortuary staff members from the Council of Forensic Medicine, Turkey. The participants were divided into the following 4 groups: forensic medicine specialists (n = 40, 28.2%), forensic medicine residents (n = 54, 38.0%), autopsy technicians (n = 24, 16.9%), and other staff members (n = 24, 16...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28691949/decline-in-postmortem-serum-tryptase-levels-in-anaphylactic-deaths
#12
Cristian Palmiere
No abstract text is available yet for this article.
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28682804/autopsy-cases-of-motorcyclists-dying-of-trauma-or-disease
#13
Arisa Takeda, Masahito Hitosugi, Satoshi Furukawa
We aimed to provide a better estimation of health-related motorcycle fatalities by comparing the backgrounds, mechanisms of injuries, and injury severity of victims who died of collision versus those who died of disease. We retrospectively analyzed autopsy records of 29 motorcyclists (mean age, 61.0 ± 21.0 years), none of whom had been driving under the influence of alcohol. Altogether, 22 (75.9%) had died of trauma, and 7 had died of disease. The disease-death victims were significantly older and had a significantly higher prevalence of a medical history compared with those with trauma-related death (100% vs 45...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28682803/the-skeleton-of-the-azzio-s-crypt-northern-italy-a-forensic-case-in-an-archaeological-context
#14
Marta Licata, Chiara Rossetti
No abstract text is available yet for this article.
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28682802/nineteen-victims-of-homicide-and-attempted-homicide-in-sweden-their-injuries-cause-of-death-and-offender-relationship
#15
Ardavan Khoshnood, Marie Väfors Fritz, Ulf Ekelund
Victims of homicide and attempted homicide are not uncommon in Sweden. We therefore aimed to study these victims to understand their injuries, their cause of death, and their relationship to the offender. All cases during five years in a district court in Sweden, where an offender had been convicted for homicide or attempted homicide, were identified and the court documents reviewed. Nineteen victims were identified; 14 males and five females, with an average age of 39.1 years. Although knife/sharp weapon was the most common weapon used, the use of firearm caused more deaths...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28665832/fourth-degree-perineal-laceration-in-nonconsenual-fisting-a-case-report-brief-review-of-the-literature-and-medicolegal-issues
#16
Simone Cappelletti, Paola Antonella Fiore, Edoardo Bottoni, Mariarosaria Aromatario
We present the case of an 18-year-old girl who was sexually assaulted with transanal forearm penetration resulting in a fourth-degree perineal laceration. Fisting is an uncommon sexual practice consisting in the penetration of the vagina, anus, or both of them with fingers, hand (fist) or forearm.Perineal lacerations are a relatively common finding in both consensual and nonconsensual fisting victims. Even though cases of fisting with first-, second-, and third-degree lacerations have been reported in literature, only one previous case of fourth-degree perineal laceration has been described in a woman, who died after anal fisting...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28665831/an-unusual-medicolegal-case-of-32-year-old-mother-and-her-29-week-fetus-with-hemolysis-elevated-liver-enzymes-and-low-platelet-count-syndrome-case-report-and-short-literature-review
#17
Michał Szeremeta, Petra Drobuliakova, Jerzy Przepieść, Janusz Załuski, Adam Sackiewicz, Anna Niemcunowicz-Janica
Forensic medicine experts are well aware of blunt abdominal trauma, which often lead to death because of serious internal organ injury with severe blood loss. Sometimes careful examination of such cases may reveal some other underlying conditions, such as an existing disease that had contributed to the death or life-threatening complications. Our article presents a rare case of spontaneous hepatic rupture and intraperitoneal hemorrhage in a 32-year-old primigravida and her 29-week fetus, which was a result of hemolysis, elevated liver enzymes, and low platelet count syndrome...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28665830/undiagnosed-pheochromocytoma-simulating-malignant-hyperthermia
#18
Nisha S Ramani, Robert Stoppacher, Ajaykumar C Morani, Charles Catanese
INTRODUCTION: Pheochromocytomas are rare catecholamine-producing neuroendocrine tumors. They are surgically curable but can be lethal if remain undiagnosed. We report a patient earlier diagnosed with malignant hyperthermia but later found to have pheochromocytoma on autopsy. CASE REPORT: After a preprocedural pain block for elective right shoulder arthroscopy, a 53-year-old hypertensive white man developed chest pain. In the operating room, he had increased blood pressure...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28657909/life-threatening-and-suspicious-lesions-caused-by-mechanical-cardiopulmonary-resuscitation
#19
Louise Milling, Peter Mygind Leth, Birgitte Schmidt Astrup
Chest compression devices for mechanical cardiopulmonary resuscitation (CPR) have become more common. Here, we report the case of a young woman who attempted resuscitated with LUCAS™2 after she was found unconscious at home. At autopsy, we found extensive intramuscular hemorrhages in posterior neck, between the scapulae, and in the lumbar region. Investigation of internal organs showed injuries to the lung, spleen, and kidney. The extension of the injuries gave rise to suspicion of homicide by smothering, which police investigation subsequently did not support...
September 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28657908/idiopathic-megacolon-report-of-2-deaths-with-review-of-the-literature
#20
Leigh Hlavaty, LokMan Sung
Abnormal dilation of the colon and rectum can develop from a range of disease processes. When encountered at autopsy, its contribution to death requires assessment and a thorough investigation of its origins. Elimination of known causes elicits a diagnosis of idiopathic megacolon. This entity is uncommonly encountered and presents with similar gross anatomic findings as Hirschsprung disease. Although death is infrequent, it most commonly results from disruption of the bowel wall and subsequent peritonitis. The authors report 2 rare deaths from idiopathic megacolon with retained integrity of the bowel wall...
September 2017: American Journal of Forensic Medicine and Pathology
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