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American Journal of Forensic Medicine and Pathology

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https://www.readbyqxmd.com/read/28525397/an-unusual-case-of-sudden-death-is-there-a-relationship-between-thyroid-disorders-and-fatal-pulmonary-thromboembolism-a-case-report-and-review-of-literature
#1
Isabella Aquila, Silvia Boca, Fiorella Caputo, Matteo A Sacco, Santo Gratteri, Vittorio Fineschi, Pietrantonio Ricci
In adults, the most common cause of sudden death is coronary heart disease or defects in the cardiac conduction system; however, there are many cases of sudden death occurring from other causes such as fatal pulmonary thromboembolism. Several risk factors are recognized, including hospitalization, surgery, obesity, pregnancy, the use of oral contraceptives, traumatic fractures, and genetic conditions, which cause hypercoagulable states such as factor V Leiden mutations. Although many risk factors have been identified, the mortality rate is still high...
May 19, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28498136/gunshot-wound-in-an-18-year-old-woman-inflicted-with-a-hunting-weapon-through-an-obstacle-mobile-phone-reconstruction-of-events
#2
Anna Smędra, Przemysław Sidelnik, Wojciech Goryca, Jarosław Berent
The article presents a case of an 18-year-old woman wounded by a shot fired from a distance with a hunting weapon. Because the location of the entrance and exit wounds initially seemed inconsistent with the reports (both wounds were described as "large and irregular in shape") and no photographs documenting the inflicted injuries were taken, the case was referred for an opinion to the Department of Forensic Medicine in Lodz. After a review of the medical records, radiology, the victim's clothing, and performance of an experiment using the gun and ammunition, it was established that the entrance wound was located on the abdomen, and the exit wound was located on the buttock...
May 12, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28426438/perceptions-and-attitudes-of-romanian-people-toward-autopsy-procedures-according-to-the-level-of-knowledge
#3
Daniela Marinescu, Gellért Attila Gyurka, Roxana Miclăuş, Codruţa Nemet, Liliana Rogozea
In the last decade, Romanian hospitals have been facing a decline in autopsy rates. This has had a negative impact on medical education and the training of young doctors. Quite a number of caregivers strongly oppose the carrying out of autopsies on their deceased loved ones who have died in hospital. Hence, this study was designed to evaluate how autopsies are perceived by an average person and whether improved knowledge about autopsies would help reduce people's reluctance toward them. The study involved 216 willing participants who had either never had a loved one die in hospital or had never had the power to make a decision about their dead loved ones' body...
April 20, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28418938/a-study-on-postmortem-wound-dating-by-gross-and-histopathological-examination-of-abrasions
#4
Javaregowda Vinay, Sathyanarayana Harish, Gouri S R Mangala, Basappa S Hugar
INTRODUCTION: Abrasions are the most common blunt force injuries. The precise dating of injury is extremely important in forensic medicine practice. As we know, the wound healing occurs in well-orchestrated sequence, consisting of inflammation, proliferation, and maturation.A study of occurrence of such phases will help in understanding the sequence of events in wound healing. In this context, this study of wound dating from gross and microscopic level was taken. MATERIALS AND METHODS: Postmortem study of wound dating by gross and histopathological examination of abrasions was carried out in the Department of Forensic Medicine, in M...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28398912/sharp-force-trauma-death-in-a-young-individual-from-medieval-gloucester
#5
Satu Valoriani, Constantine Eliopoulos, Matteo Borrini
The authors of the present work evaluate the trauma observed on the skeletal remains of an individual from medieval Gloucester and reconstruct the events that led to his death. The almost complete skeleton was recovered from the cemetery of St Owen and dates to the late medieval period. Several methods were used to determine the sex and age of the individual. The anthropological examination showed that the remains belonged to a young male, between the ages of 17 and 19 years. The young man also had antemortem pathologies that were related to his diet and lifestyle, as he appears to have had iron-deficiency anemia and Schmorl nodes...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28398911/increased-epicardial-fat-thickness-in-sudden-death-from-stable-coronary-artery-atherosclerosis
#6
Belinda Fuller, Jack Garland, Sravan Anne, Raymond Beh, Dennis McNevin, Rexson Tse
BACKGROUND: Sudden death from stable coronary artery atherosclerosis (SCAA) is well recognized. However, individuals can have ischemic heart disease or coronary artery atherosclerosis but die of noncardiac causes. Recently, it has been recognized that increased epicardial fat is detrimental to normal heart function. We hypothesize that individuals who die of SCAA have increased epicardial fat. AIM: The aim of this study was to investigate whether there is an increase in epicardial fat in individuals who suddenly died of SCAA...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28333700/intimate-partner-violence-a-rare-case-of-reciprocal-homicide
#7
Aurélie Cauchois, François Paraire, Geoffroy Lorin de la Grandmaison
We present the case of a reciprocal homicide by stabbing that occurred within an unmarried couple without known history of spousal violence. Each partner killed the other one at the same time and at the same place using kitchen knives. They were both found dead at home lying on the floor after the neighbors heard an argument and screams coming from the couple's apartment, so they called the police and the fire department. The door was locked from the inside, and the fire department was forced to break the door...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28319470/symptomatic-acute-on-chronic-subdural-hematoma-a-clinicopathological-study
#8
Rudy J Castellani, Gruschenka Mojica-Sanchez, Gary Schwartzbauer, David S Hersh
The pathophysiology of acute-on-chronic subdural hematoma (ACSDH) is complex and incompletely understood. Evidence to date indicates that the overall process is initiated by rotational force with movement of the brain inside the skull, which exerts tensile strain and rupture of bridging veins, leading in turn to acute hemorrhage in the subdural potential space. This is followed by the proliferation of mesenchymal elements with angiogenesis and inflammation, which in turn becomes a substrate for repeated hemorrhage and expansion of the lesion...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28272091/asphyxia-in-motor-vehicle-crashes-analysis-of-crash-related-variables-using-national-automotive-sampling-system-crashworthiness-data-system-and-forensic-case-studies
#9
Steven G Storvik, Julius Q Campbell, Jeffrey B Wheeler
Rates of death because of asphyxia in motor vehicle crashes have been previously estimated using county and statewide data sets, but national estimates have not been reported. The literature regarding asphyxia in motor vehicle crashes primarily involves discussions about clinical findings, and crash-related variables have been sparsely reported. The current study calculated a nationwide fatality rate for asphyxia in motor vehicle crashes of 1.4%. Seventeen case studies of asphyxia were also reported providing crash-, vehicle-, and occupant-related variables...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28272090/subtentorial-meningioma-misdiagnosed-as-cerebral-hemorrhage-in-postmortem-computed-tomography-imaging-a-case-report
#10
Hui Qian, Yu Shao, Zhengdong Li, Donghua Zou, Jianhua Zhang, Maowen Wang, Lei Wan, Yijiu Chen
This report presents a case of a 52-year-old man who had a traffic accident and died later. External examination could not determine the cause of death. Approximately 3 weeks later, an autopsy was performed. Postmortem computed tomography was performed before the autopsy. Postmortem imaging was interpreted to show hemorrhage beneath the tentorium, and the C5 to C6 (the fifth and sixth cervical vertebra) disc space was widened. During the autopsy, a cervical spinal cord injury was confirmed. However, a meningioma was found under the tentorium instead of a hemorrhage...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28272089/mediators-of-inflammation-in-asthma-a-forensic-perspective
#11
Maria Laura Schirripa, Maria Pia Scarpelli, Cristian Palmiere
In the clinical setting, the role of systemic inflammation in patients with asthma has attracted increased attention, and some authors showed that increased IL-6 and high-sensitivity C-reactive protein characterized a group of asthmatic patients. In the realm of forensic pathology, a postmortem diagnosis of asthmatic death can be extremely challenging. The aim of this study was to determine the postmortem serum levels of C-reactive protein, IL-6, and tumor necrosis factor α in a series of severe acute bronchial asthma deaths that underwent medicolegal investigations...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28263236/forensic-image-analyses-of-skin-and-underlying-muscles-as-a-tool-for-postmortem-interval-delimitation-histopathologic-examination
#12
El-Shaymaa El-Nahass, Walaa A Moselhy, Nour El-Houda Y Hassan
One of the biggest challenges for forensic pathologists is to diagnose the postmortem interval (PMI) delimitation; therefore, the aim of this study was to use a routine histopathologic examination and quantitative analysis to obtain an accurate diagnosis of PMI. The current study was done by using 24 adult male albino rats divided into 8 groups based on the scarification schedule (0, 8, 16, 24, 32, 40, 48, and 72 hours PMI). Skin specimens were collected and subjected to a routine histopathologic processing...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28263235/unusual-case-of-suicide-with-a-modified-trap-gun
#13
Amal Vadysinghe, Prasanna Dassanayake, Medhani Wickramasinghe
INTRODUCTION: Trap gun is an illegal, locally manufactured gun with a basic trip system used to hunt wild animals. CASE REPORT: The body of a 28-year-old man was found in the jungle in supine position with both legs apart. A trap gun was between the legs pointing toward the cranial side of the body. It had 2 free wires that were not connected together. There was no evidence of foul play.The body had a single-entry wound (2.5-cm diameter) in the anterior chest, with blackening, burning, and tattooing...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28263234/evaluation-of-a-novel-and-standardized-technique-for-subcutaneous-upper-limb-dissection
#14
Sam Hoggard, Charles A Wilson
It is often necessary to dissect the subcutaneous tissues to confirm or exclude the presence of cutaneous bruising. We undertook a literature search that demonstrated that there is currently no standardized technique for subcutaneous dissection, and the specific incisions and dissections used probably vary between individual pathologists. It is our experience that dissections wider than the area of cutaneous bruising visible externally often reveal bruises not identified on external inspection. We propose a standardized technique for subcutaneous dissection of the upper limb that allows direct inspection of the subcutaneous tissues of the forearm and dorsum of the hand...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28263233/cardiotoxic-arrhythmogenic-effects-of-1-1-difluoroethane-due-to-electrolyte-imbalance-and-cardiomyocyte-damage
#15
Kaushal Joshi, Michael Barletta, John Wurpel
Inhalant abuse is the intentional inhalation of chemical vapors to attain euphoric effects. Many common household products are abused by inhalation and one is 1,1-difluoroethane (DFE), which is a halogenated hydrocarbon used in refrigeration, dust-off spray, and airbrush painting. Although many human DFE abuse cases have been studied, the etiology and mechanism of sudden death is still unknown. In this study, an animal model was used to simulate the human conditions of DFE inhalation abuse that results in sudden death...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28230653/suicides-by-jumping-off-istanbul-bridges-linking-asia-and-europe
#16
Ayşe Yurtseven, İbrahim Üzün, Murat Nihat Arslan
AIM: The aim of this study was to determine the injury spectrum and characteristics of people who committed suicide by jumping into water from the July 15th Martyrs Bridge and Fatih Sultan Mehmet Bridges in Istanbul, Turkey. METHODS: This study included all of the jumpers from the July 15th Martyrs Bridge and Fatih Sultan Mehmet Bridge who were autopsied by the Council of Forensic Medicine, Istanbul Morgue Department, between 2000 and 2013. All of the data were collected from archived case files...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28230652/a-case-of-postmortem-canine-depredation
#17
Dennis J Chute, Robert J Bready
We report the case of postmortem animal depredation that produced initial confusion for investigators who responded to the scene. A decomposing elderly woman was found in her presumed home with bilateral upper extremity amputations and craniocerebral trauma. This raised suspicion of foul play. Subsequent investigations together with autopsy led the medical examiner to conclude that the cause of death was natural disease and that those injuries found on her body were produced by at least one of the dogs who shared the premises...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28114174/case-report-lightning-induced-pneumomediastinum
#18
Ryan Blumenthal, Gert Saayman
We present the case of a 41-year-old woman who was fatally injured during a witnessed lightning strike event and in whom autopsy revealed the unusual keraunopathological finding of overt pneumomediastinum. The possible pathophysiological mechanism(s) of causation of this phenomenon are discussed, with specific reference also to the "Macklin" effect and the role of blast overpressures associated with lightning strike. It is suggested that the latter may lead to sudden alveolar rupture, with subsequent rapid tracking of air along bronchovascular sheaths in a centripetal manner toward the hilum of the lung and thus into the mediastinum...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28106684/sudden-death-due-to-unusual-complication-of-takayasu-arteritis-an-autopsy-case
#19
Maher Jedidi, Youssef Chkirbene, Nihed Abdessayed, Tasnim Masmoudi, Mohamed Mahjoub, Souheil Mlayeh, Mohamed Ben Dhiab, Mohamed Kamel Souguir, Mohamed Taher Yacoubi
Takayasu arteritis is an uncommon inflammatory disease with usually a good prognosis. However, sometimes, the evolution can be fatal essentially by a coronary arteries involvement. We present a case of a 19-year-old woman who died suddenly from cardiogenic shock complicating an unknown Takayasu arteritis.At the autopsy, the aorta showed a significant thickening of the wall. The coronary arteries were slightly thickened and did not show any occlusion. Microscopic examination of the aorta showed an abundant granulomatous and a lymphoplasmacytic infiltrate...
June 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28085681/basal-ganglion-hemorrhage-as-delayed-complication-of-diethylene-glycol-ingestion
#20
Avneesh Gupta, Francisco J Diaz, Anita Lal, Lokman Sung, Cynthia K Aaron
Diethylene glycol (DEG), an organic compound (HOCH2CH2)2O is a commonly used solvent. Mass poisoning outbreaks have been reported because of frequent contaminations. A PubMed search for diethylene resulted in 795 publications with 151 specifically discussing the toxicity. Of the 151 reported toxicity reviews/case reports, only 6 publications discussed the long-term neurological effects of diethylene toxicity. We report a fatal case of oral ingestion of DEG with complications from delayed toxicity. She died 7 days after the second admission...
March 2017: American Journal of Forensic Medicine and Pathology
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