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Iranian Journal of Medical Sciences

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https://www.readbyqxmd.com/read/28533583/high-grade-urothelial-carcinoma-of-bladder-transforming-to-micropapillary-variant-on-follow-up
#1
Nitu Kumari, Anupama Jha, Pawan Vasudeva, Usha Agrawal
Micropapillary variant of urothelial carcinoma (UC) of the bladder is an aggressive tumour, comprising 0.6-6% of all UC. It generally presents with high-grade and stage, and has been reported as having a worse prognosis when compared to traditional UC. We report the case of a 58-year-old man who presented with macroscopic haematuria. The patient was diagnosed with high-grade urothelial carcinoma and returned with recurrence after 16 months. Histopathology after transurethral biopsy revealed a non-muscle invasive high-grade bladder tumour at first presentation, whereas tumour recurrence was reported after 1...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533582/angular-ectopic-pregnancy-presenting-as-rupture-of-lateral-wall-of-the-uterus-late-presentation-in-gestation-week-20
#2
Malihe Hasanzadeh, Salme Dadgar, Yalda Arian, Yousef Yousefi
The differential diagnosis of acute abdominal pain in pregnancy is broad and can be complicated by atypical manifestations that are due to the anatomic distortions and physiologic changes of pregnancy. Due to the lack of clinical understanding, angular pregnancy does not appear to be recognized as a clinical entity and many cases are likely to go undiagnosed. This is a case report of a 34-year-old woman who was referred to the obstetrics emergency department with sudden abdominal pain and in a state of hypovolemic shock...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533581/bicuspid-aortic-valve-an-unusual-cause-of-aneurysm-of-left-coronary-sinus-of-valsalva
#3
Euden Bhutia, Dinesh Kumar, Binoy Shankar, Shakti Pad Das, Sunil Kishore
Bicuspid aortic valve is traditionally considered an innocuous congenital anomaly. Due to a better and widespread availability of non-invasive imaging techniques, it has come to the fore that 30% of these cases develop complications, viz., valve abnormality (aortic regurgitation and stenosis), and aneurysm of aortic root and ascending aorta. Sinus of Valsalva aneurysm is an uncommon complication of bicuspid aortic valve and more so those arising from the left coronary sinus are the rarest. These complications generally occur in the third or fourth decade of life...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533580/olanzapine-induced-neuroleptic-malignant-syndrome
#4
Seyedhamze Hosseini, Forouzan Elyasi
Neuroleptic malignant syndrome (NMS) is a rare but life-threatening idiosyncratic side effect resulting from neuroleptic drugs. NMS mainly occurs in patients treated with high-potency typical antipsychotics, but rarely caused by atypical antipsychotics. Although NMS is less common with atypical antipsychotic, but it seems that its incidence is rising due to increased administration of such drugs. We present the case of a 27-year-old man with a history of paranoid schizophrenia that showed signs consistent with NMS that occurred after treatment with olanzapine...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533579/relationship-between-body-mass-index-waist-to-hip-ratio-and-serum-lipid-concentrations-and-thyroid-stimulating-hormone-in-the-euthyroid-adult-population
#5
Ali Reza Rahbar, Mohamadreza Kalantarhormozi, Fatemeh Izadi, Elham Arkia, Marzie Rashidi, Fatemeh Pourbehi, Farzaneh Daneshifard, Amin Rahbar
The aim of this cross-sectional study was to investigate the relationship between body mass index (BMI), waist-to-hip ratio, and lipid parameters and serum thyroid-stimulating hormone (TSH) levels in healthy euthyroid individuals. This cross-sectional study was conducted between June 1(st) and July 20(th), 2013, at Bushehr University of Medical Sciences. One hundred forty euthyroid individuals were divided into 2 groups: a high-TSH group (TSH between 2.0 and 5.5 mIU/L, n=67) and a low-TSH group (TSH between 0...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533578/validity-and-reliability-assessment-of-the-persian-version-of-therapy-related-symptom-checklist
#6
Ava Mansouri, Rozita Motaghedi, Arash Rashidian, Asieh Ashouri, Mona Kagrar, Moluk Hajibabaei, Kheirollah Gholami, Shahla Ansari
Therapy-related symptom checklist for children (TRSC-C) was developed as a symptom assessment tool in children receiving chemotherapy. The objective of the present study was to evaluate the validity and reliability of the Persian version of TRSC-C. This cross-sectional study was conducted in 2013-2014 in Tehran, Iran. TRSC-C was translated using backward-forward approach. The content validity, face validity, and comprehensiveness were investigated based on the opinion of experts. The item content validity index (I-CVI) and scale content validity index (S-CVI) were calculated by the mean approach and inter-rater agreement...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533577/the-interaction-between-trolox-and-4-4-diisothiocyanatostilbene-2-2-disulfonic-acid-on-hypoxic-pulmonary-vasoconstriction-in-the-isolated-rabbit-lung
#7
Somayh Mansoori, Seyed Mostafa Shid Moosavi, Farzaneh Ketabchi
BACKGROUND: The mechanism of hypoxic pulmonary vasoconstriction (HPV) is still debatable. It has been proposed that reactive oxygen species (ROS) might be involved in HPV. However, there is no special transporter for superoxide anion in the cell membrane and it may release from the cells via anion exchanger. Therefore, the aim of this study was to investigate the interaction of ROS and anion exchanger in acute HPV. METHODS: The present study was performed in the isolated rabbit lung...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533576/ifn-%C3%AE-and-il-2-responses-to-recombinant-aladh-against-esat-6-cfp-10-fusion-antigens-in-the-diagnosis-of-latent-versus-active-tuberculosis-infection
#8
Bahram Movahedi, Pooneh Mokarram, Mina Hemmati, Nader Mosavari, Razie Zare, Leila Safaee Ardekani, Zohreh Mostafavi-Pour
BACKGROUND: Discriminating latent tuberculosis infection (LTBI) from active TBI may be challenging. The objective of this study was to produce the recombinant L-alanine dehydrogenase (AlaDH) antigen and evaluate individuals with LTBI, those with active TBI, and uninfected individuals by enzyme-linked immunospot assay (ELISPOT) in order to distinguish LTBI from active TBI. METHODS: This exploratory study was performed in the Iranian city of Shiraz from 2014 to 2015...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533575/antihypertensive-effects-of-hydroalcoholic-extract-of-crataegus-azarolus-subspecies-aronia-fruit-in-rats-with-renovascular-hypertension-an-experimental-mechanistic-study
#9
Mohammad Reza Haydari, Mohammad Reza Panjeshahin, Elaheh Mashghoolozekr, Ali Akbar Nekooeian
BACKGROUND: Hawthorn species decreases blood pressure and relaxes precontracted vessels. This study aimed at examining the antihypertensive effect and related mechanisms of hydroalcoholic extract of Crataegus azarolus subspecies aronia fruit in rats with renovascular hypertension. METHODS: Six groups of male Sprague-Dawley rats, each containing 6 to 8 rats, were studied. The groups comprised of one sham group and 5 renal artery-clipped groups. The sham group received vehicle (distilled water 0...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533574/in-vitro-radiosensitizing-effects-of-temozolomide-on-u87mg-cell-lines-of-human-glioblastoma-multiforme
#10
Samira Borhani, Hossein Mozdarani, Somayyeh Babalui, Mohsen Bakhshandeh, Hassan Nosrati
BACKGROUND: Glioma is the most common primary brain tumor with poor prognosis. Temozolomide (TMZ) has been used with irradiation (IR) to treat gliomas. The aim of the present study was to evaluate the cytotoxic and radiosensitizing effect of TMZ when combined with high-dose and high-dose rate of gamma irradiation in vitro. METHODS: Two 'U87MG' cell lines and skin fibroblast were cultured and assigned to five groups for 24, 48, and 72 hours. The groups were namely, TMZ group (2000 μM/L), IR group (5 Gy), TMZ plus IR group, control group, and control solvent group...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533573/comparison-of-early-results-and-complications-between-multi-and-single-port-sleeve-gastrectomy-a-randomized-clinical-study
#11
Seyed Vahid Hosseini, Seyed Ali Hosseini, Ahmed Mohammed Ali Hussein Al-Hurry, Hajar Khazraei, Fatemeh Ganji, Fatemeh Sadeghi
BACKGROUND: In recent years, laparoscopic sleeve gastrectomy (LSG) has become more acceptable for obese patients. Single-port sleeve gastrectomy (SPSG) is more popular since each abdominal incision carries the risk of bleeding, hernia, and internal organ injury as well as exponentially affecting cosmesis. This cross-sectional study aimed at comparing multi-port sleeve gastrectomy (MPSG) and SPSG in terms of their early results and complications. METHODS: Out of129 obese patients candidated for LSG, 102 patients were assigned to 2 groups of SPSG and MPSG...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533572/%C3%AE-lipoic-acid-mitigates-arsenic-induced-hematological-abnormalities-in-adult-male-rats
#12
Sonali Ghosh, Raghwendra Mishra, Sagnik Biswas, Rupak K Bhadra, Prabir K Mukhopadhyay
BACKGROUND: Arsenic toxicity is a major global health problem and exposure via contaminated drinking water has been associated with hematological and other systemic disorders. The present investigation has been conducted in adult male rats to evaluate the protective ability of α-lipoic acid (ALA) against such hematological disorders. METHODS: Twenty-four adult male Wister rats (b.wt.130±10g) were grouped and accordingly group I (control) received the normal diet, group II (treated) was given arsenic orally for 28 consecutive days as arsenic trioxide (3 mg/kgbw/rat/day) whereas group III (supplemented) received the same dose of arsenic along with ALA (25 mg/kgbw/rat/day) as oral supplement...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533571/local-infiltration-of-tramadol-versus-bupivacaine-for-post-cesarean-section-pain-control-a-double-blind-randomized-study
#13
Mohammad Ali Sahmeddini, Simin Azemati, Ehsan Masoudi Motlagh
BACKGROUND: Postoperative pain control after cesarean section (C/S) is important because inadequate postoperative pain control can result in a prolonged hospital stay. In this study, we compared postoperative somatic wound pain control between patients receiving tramadol and bupivacaine, infiltrated at the wound site. METHODS: In this randomized clinical trial, 98 patients, eligible for elective C/S under general anesthesia, were randomly allocated to 2 groups. Before wound closure, 20 cc of 0...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28533570/awareness-and-observance-of-patient-rights-from-the-perspective-of-iranian-patients-a-systematic-review-and-meta-analysis
#14
REVIEW
Ghassem Abedi, Jalil Shojaee, Mahmood Moosazadeh, Farideh Rostami, Aliasghar Nadi, Ehsan Abedini, Charles John Palenik, Mehrdad Askarian
BACKGROUND: Recipients of healthcare services have rights, which must be acknowledged and protected. Such rights include observance of acceptable patient physical, mental, spiritual, and social needs guided by commonly accepted rules and regulations. The objective of this study was to conduct a systematic review and meta-analysis of awareness rates and observance of patient rights in Iran from the perspective of the patient. METHODS: In this study, various references such as Medline (PubMed), Scopus, Scientific Information Database (SID), Google scholar, Magiran, and IranMedex were searched (from August to December 2015)...
May 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28360452/cobra-head-stone-in-single-system-ureterocele
#15
Selahattin Çalışkan
No abstract text is available yet for this article.
March 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28360451/effects-of-mutational-combinations-on-philadelphia-negative-myeloproliferative-neoplasms
#16
Yonal-Hindilerden Ipek, Daglar-Aday Aynur, Hindilerden Fehmi, Nalcaci Meliha, Yavuz Akif Selim, Sargin Deniz
No abstract text is available yet for this article.
March 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28360450/renal-medullary-carcinoma-a-rare-entity
#17
Selahattin Çalışkan, Ali Murat Gökçe, Gülistan Gümrükçü, Mine Önenerk
Renal medullary carcinoma (RMC) is an uncommon aggressive neoplasm of the kidney. RMC is biologically aggressive with a very poor prognosis, and metastasis is seen in up to 95% of the patients at diagnosis or shortly thereafter. The common sites of metastasis are respectively lymph nodes, lungs, livers, and adrenal glands in order of frequency. The presence of poorly differentiated eosinophilic cells in a characteristic fibro-inflammatory stroma is seen in histological examination. The origin and pathogenesis of RMC are unclear...
March 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28360449/balanced-reciprocal-translocation-t-x-1-in-a-girl-with-tall-stature-and-primary-amenorrhea
#18
Zahra Razavi, Hossein Emad Momtaz
Chromosomal translocations constitute one of the most important, yet uncommon, causes of primary amenorrhea and gonadal dysgenesis. Although X-autosome translocations are frequently associated with streak gonads and clinical features of the Turner syndrome, the majority of X-autosome carriers may present with a variable phenotype, developmental delay, and recognizable X-linked syndrome due to nonrandom X-inactivation. In this article, we describe a healthy 15.5-year-old girl with primary amenorrhea, gonadal dysgenesis, and tall stature without other manifestations of the Turner syndrome...
March 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28360448/tumefactive-fibroinflammatory-lesion-a-diagnostic-dilemma
#19
Promil Jain, Rajeev Sen, Nisha Sharma, Shilpi Bhargava, Virender Singh
Tumefactive fibroinflammatory lesions (TFLs) are rare idiopathic benign fibrosclerosing lesions that clinically simulate a malignancy. TFLs are seen more frequently in males between 10 and 74 years of age. The usual site of involvement is the head and neck region, but rarely the extremities may be involved. Coexisting fibrosclerotic processes have been reported including retroperitoneal fibrosis, sclerosing cholangitis, sclerosing mediastinal fibrosis, and orbital pseudotumors. The etiology of this poorly understood entity remains unknown...
March 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28360447/botulism-outbreak-in-a-family-after-ingestion-of-locally-produced-cheese
#20
Shahram Rafie, Shokrollah Salmanzadeh, Asieh Mehramiri, Adel Nejati
Botulism is one of the most important foodborne diseases and is caused by Clostridium botulinum toxin. The main manifestations are flaccid muscle paralysis and cranial nerve palsies. Botulism is an essential health problem because of its high mortality. The diagnosis of botulism, especially in sporadic cases, is a medical challenge and a high clinical suspicion is necessary for early recognition. So, every physician should be familiar with its signs and symptoms for early detection and treatment. We describe a family with dysphasia and acute paralysis after the ingestion of locally made cheese...
March 2017: Iranian Journal of Medical Sciences
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