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Iranian Journal of Medical Sciences

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https://www.readbyqxmd.com/read/29184272/approach-to-chronic-secondary-headache-a-case-report-on-unusual-drug-side-effects
#1
Hamid Reza Riasi, Forod Salehi, Morteza Hajihosseini
In this article, we present the case of a 12-year-old female child who complained of bilateral temporal and frontal headache for 2 to 3 months with nausea and vomiting. Physical examination revealed right-sided sixth cranial nerve palsy and papilledema in ophthalmoscopy. To find the cause of increased intracranial pressure, the patient underwent brain imaging and brain MRI showed no abnormality. Ultimately, lumbar puncture (LP) was performed and cerebrospinal fluid (CSF) pressure was 280 mmH2O with normal chemistry...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184271/a-case-of-cushing-s-syndrome-in-pregnancy
#2
Leila Pourali, Atiyeh Mohammadzade Vatanchi, Anahita Hamidi
Cushing's syndrome (CS) occurs rarely during pregnancy. CS can be caused by prolonged abnormal exposure to excess glucocorticoids leading to special and significant signs and symptoms. It is often difficult to diagnose pathological hypercortisolism in pregnant women since some symptoms of the disease might be due to a complicated pregnancy, including preeclampsia or gestational diabetes. In this study, we report the case of a 29-year-old female who referred to our institution with hypertension, weakness, steria, and truncal obesity...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184270/recurrent-psammomatoid-juvenile-ossifying-fibroma-with-aneurysmal-bone-cyst-an-unusual-case-presentation
#3
Swati S Gotmare, Avinash Tamgadge, Sandhya Tamgadge, Kashmira S Kesarkar
Juvenile ossifying fibroma (JOF) is a rare, benign, locally aggressive entity of the extragnathic craniofacial bones with a high tendency towards recurrence. Two distinctive microscopic patterns of juvenile ossifying fibroma have been described: a trabecular juvenile ossifying fibroma (TrJOF) and a psammomatoid juvenile ossifying fibroma (PJOF). Psammomatoid variant is predominantly a craniofacial lesion and occurs rarely in the jaws. The pathognomonic histopathologic feature is the presence of spherical ossicles, which are similar to psammoma bodies...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184269/different-presentation-of-anomalous-origin-of-the-left-coronary-artery-from-the-pulmonary-artery-in-adults-case-reports
#4
Alwaleed Al-Dairy, Yousef Rezaei, Maziar Gholampour Dehaki, Anita Sadeghpour, Zia Totonchi, Hamidreza Pouraliakbar, Alireza Alizadeh Ghavidel
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital cardiac malformation. We report three cases of ALCAPA who survived to adulthood. The first case was a 51-year-old woman who complained of typical chest pain that was diagnosed with ALCAPA using cardiac catheterization and coronary computed tomographic angiography (CTA). The second case was a 30-year-old woman with a history of surgery for atrial septal defect at 10 years old who presented with progressive exertional dyspnea...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184268/impacts-of-bone-marrow-stem-cells-on-caspase-3-levels-after-spinal-cord-injury-in-mice
#5
Noushin Gashmardi, Seyed Ebrahim Hosseini, Davood Mehrabani, Mohammad Amin Edalatmanesh, Zahra Khodabandeh
Spinal cord injury (SCI) is a drastic disability that leads to spinal cord impairment. This study sought to determine the effects of bone marrow stem cells (BMSCs) on caspase-3 levels after acute SCI in mice. Forty-two mice were randomly divided into 3 groups: control (2 subcategories), subjected to no intervention; sham (3 subcategories), subjected to acute SCI; and experimental (2 subcategories), subjected to SCI and cell transplantation. In the experimental group, 2×105 BMSCs were injected intravenously 1 day after SCI...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184267/deltamethrin-induced-hepatotoxicity-and-virgin-olive-oil-consumption-an-experimental-study
#6
Ali Reza Khalatbary, Davood Nasiry Zarrin Ghabaee, Hassan Ahmadvand, Fereshteh Talebpour Amiri, Somaieh Tadayoni Lehi
Background: Deltamethrin (DM) is a synthetic pyrethroid insecticide which can lead to pathological effects in mammals through oxidative stress. On the other hand, virgin olive oil (VOO) is a rich source of phenolic compounds with antioxidants. The aim of the present study was to determine the protective effects of VOO against DM-induced hepatotoxicity. Methods: Thirty-six mice were randomly separated into 4 groups: vehicle group, VOO group, DM group, and DM plus VOO group...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184266/effects-of-saponin-from-trigonella-foenum-graecum-seeds-on-dyslipidemia
#7
Zhi Chen, Yan-Li Lei, Wen-Ping Wang, Ya-Ya Lei, Yan-Hua Liu, Jing Hei, Jin Hu, Hong Sui
Background: Saponins identified from fenugreek (Trigonella foenum-graecum) seeds are reported effective on dyslipidemia. However, the definite mechanism is still not elucidated systematically. In this study, we evaluate the effects of saponin extract on cholesterol absorption, metabolism, synthesis, and reverse cholesterol transport in vivo. Methods: Saponin extract was prepared according to a craft established in our previous study. After the establishment of dyslipidemia model, 40 male Sprague-Dawley rats were divided into five groups, namely the control group (normal diet plus normal saline), HFD group (high fat diet plus normal saline), Lipitor group (high fat diet plus Lipitor (2 mg/kg)), and L, M, and H-saponin groups (high fat diet plus saponin in dosages of 6, 12, and 24 mg/kg, respectively)...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184265/long-term-low-intensity-endurance-exercise-along-with-blood-flow-restriction-improves-muscle-mass-and-neuromuscular-junction-compartments-in-old-rats
#8
Mohammad-Ali Bahreini Pour, Siyavash Joukar, Fariborz Hovanloo, Hamid Najafipour
Background: During the aging process, muscle atrophy and neuromuscular junction remodeling are inevitable. The present study aimed to clarify whether low-intensity aerobic exercise along with limb blood-flow restriction (BFR) could improve aging-induced muscle atrophy and nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. Methods: Forty-eight male Wistar rats, aged 23-24 months, were randomly divided into control, sham (Sh: subjected to surgery without BFR), BFR (subjected to BFR), exercise (Ex: subjected to 10 weeks of low-intensity exercise), Sh+Ex, and BFR+Ex groups...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184264/effects-of-subacute-administration-of-co-trimoxazole-and-folic-acid-on-ovarian-tissue-in-adult-female-rats
#9
Arezoo Saberi, Ehsan Salarkia, Zohreh Safi, Gholamreza Sepehri
Background: Previous studies have reported the antifertility activities of sulfonamides. This study was designed to evaluate the effects of co-trimoxazole and its co-administration with folic acid on ovarian tissue in female rats. Methods: A total of 54 rats were randomly divided into 9 groups (n=6). Group I served as the control and group II (vehicle) received saline. Other groups, III to IX, received co-trimoxazole (30, 60, and 120 mg/kg; i.p.), folic acid (1 mg/kg; i...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184263/antidiabetic-and-antidyslipidemic-activities-of-the-aqueous-extract-of-cochlospermum-planchonii-leaves-in-streptozotocin-induced-diabetic-rats
#10
Bamisaye Fisayo Abraham, Sulyman Abdulhakeem Olarewaju, Abegunde Ronke, Ajani Emmanuel Oladipo
Background: Diabetes mellitus is considered one of the 5 principal causes of death in the world and is recognized as a global public health issue because of its multifactorial facets affecting essential biochemical processes in the body. This study investigated the antidiabetic and antidyslipidemic activities of the aqueous extract of Cochlospermum planchonii (C. planchonii) leaves in streptozotocin (STZ)-induced diabetic rats. Methods: Thirty adult female rats (Rattus norvegicus) weighing 153±3...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184262/cerebral-ischemia-reperfusion-injuries-in-vanadyl-treated-diabetic-rats
#11
Hossein Ahmadi-Eslamloo, Seyed Mostafa Shid Moosavi, Gholam Abbas Dehghani
Background: Ischemic stroke recovery is poor in diabetic mellitus (DM). Vanadium compounds (vanadium) relieve DM signs, but their influences on cerebral ischemia/reperfusion injury (I/RI) are inconclusive. Herein, the intensity of I/RI was inspected in vanadium-treated DM rats. Methods: Rats made diabetic with a single intravenous dose of streptozocin (39 mg/kg). Normal and DM rats used water or vanadyl solution for 45 days. Under isoflurane anesthesia, right middle cerebral artery occlusion was performed for 60 minutes and 12 hours reperfusion...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184261/adherence-to-the-consort-statement-in-the-reporting-of-randomized-controlled-trials-on-pharmacological-interventions-published-in-iranian-medical-journals
#12
Pooneh Sarveravan, Behrooz Astaneh, Nasrin Shokrpour
Background: Among manuscripts submitted to biomedical journals, randomized controlled trials (RCTs) form the backbone of evidence-based medicine. Hence, their protocol should be designed rigorously and their results should be reported clearly. To improve the quality of RCT reporting, researchers developed the CONSORT Statement in 1996 and updated it in 2010. This study was designed to assess the quality of RCT reporting vis-à-vis adherence to CONSORT among articles published in Iranian medical journals (English, Persian, CONSORT-endorsing, and non-CONSORT-endorsing)...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184260/topical-effects-of-artemisia-absinthium-ointment-and-liniment-in-comparison-with-piroxicam-gel-in-patients-with-knee-joint-osteoarthritis-a-randomized-double-blind-controlled-trial
#13
Zahra Basiri, Fatemeh Zeraati, Farzaneh Esna-Ashari, Farshid Mohammadi, Keyvan Razzaghi, Malihe Araghchian, Shirin Moradkhani
Background: Pain alleviation and improvement of functional status are the main objectives in the treatment of osteoarthritis. Artemisia absinthium (AA) was used traditionally in reducing pain and inflammation. The aim of the present study was to compare the effects of topical formulations of AA and piroxicam gel (PG) among patients with knee osteoarthritis. Methods: In total, 90 outpatients aged 30-70 years with the diagnosis of primary osteoarthritis in at least one knee were enrolled in a randomized double-blind clinical trial...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29184259/isolated-peritoneal-mesenteric-and-omental-hydatid-cyst-a-clinicopathologic-narrative-review
#14
REVIEW
Bita Geramizadeh
Hydatid disease (HD) is caused by Echinococcus granulosus and is endemic in many parts of the world. This parasitic tapeworm can produce cysts in almost every organ of the body, with the liver and lung being the most frequently targeted organs. Peritoneum, omentum, and mesentery are among these unusual locations, which can cause diagnostic challenge and treatment delay. This review provides information on the reported cases of the peritoneal, omental, and mesenteric hydatid cyst in the world during the last 20 years...
November 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29234188/cranial-nerve-lymphomatosis-magnetic-resonance-imaging-findings-in-a-case-of-mantle-cell-lymphoma
#15
Güliz Yılmaz, Süha Akpınar, Nail Bulakbaşı
No abstract text is available yet for this article.
September 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29234187/efficacy-of-%C3%AE%C2%B5-poly-l-lysine-as-an-antibacterial-additive-for-platelets-stored-at-room-temperature
#16
Hosein Timori Naghadeh, Zohreh Sharifi, Saeideh Soleimani, Zainab Pir Mohamad Jamaat, Shirin Ferdowsi
No abstract text is available yet for this article.
September 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29234186/primary-leiomyosarcoma-of-the-mesentery-a-case-report
#17
Varsha Dalal, Manveen Kaur, Reetika Menia, Fouzia Siraj, Amar Bhatnagar, Usha Agrawal
Mesenteric masses are infrequent lesions ranging from benign cysts to aggressive malignancies and often present a diagnostic and therapeutic challenge. The mesentery is a frequent recipient of metastases from the gastrointestinal tract, pancreas, and biliary cancers. Primary mesenteric tumors are relatively rare, mostly mesenchymal in origin and benign in nature. Examples include gastrointestinal stromal tumors and smooth muscle tumors. We describe a 50-year-old woman, who presented with a lump in the left hypochondrium along with altered bowel habits of 2 years' duration...
September 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29234185/ellis-van-creveld-with-an-unusual-dental-anomaly-a-case-report
#18
Suzanne Tanya Nethan, Shruti Sinha, Sunira Chandra
The Ellis-van Creveld (EVC) syndrome is a chondroectodermal dysplasia and is characterized by the cardinal features of disproportionate short stature, polydactyly, hidrotic ectodermal dysplasia, and congenital heart malformations, along with other skeletal and dental abnormalities. It is a rare condition, with very few cases reported in the medical literature. It is inherited as an autosomal recessive disorder with variable expressions, due to the mutation of the EVC syndrome 1 and 2 genes, which are located on chromosome 4p16...
September 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29234184/a-rare-case-of-fixed-drug-eruption-due-to-ondansetron
#19
Aditi Maitra, Shashwat Bhattacharyya, Sabyasachi Paik, Prerna Pathak, Santanu Kumar Tripathi
Fixed drug eruption (FDE) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. FDE is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. A 27-year-old woman presented with multiple dark patches over her eyelids, mouth, lips, and shoulders of 1 week's duration. These lesions followed multiple erythematous plaques over the same areas which appeared within 4 hours of the intake of an ondansetron tablet, 12 days previously...
September 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29234183/lymph-node-enlargement-in-neck-filariasis-as-a-rare-cause-a-case-report
#20
Rindu Raveendran
Lymphatic filariasis is endemic to tropical countries and is the most common cause of acquired lymphedema in the world. Wuchereria bancrofti is the main etiological agent responsible. While the presentation of filariasis in limbs is common, isolated presentation as a single enlarged lymph node in the neck is very rare. We describe a 48-year-old Indian woman, who presented with a hard lymph node in the neck. There was no other significant lymph node enlargement. The overlying skin was erythematous, and no other findings were present on examination...
September 2017: Iranian Journal of Medical Sciences
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