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Current Eye Research

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https://www.readbyqxmd.com/read/28157425/clinical-features-and-prognostic-factors-in-presumed-ocular-tuberculosis
#1
Cristhian A Urzua, Yrbani Lantigua, Sergio Abuauad, Paulina Liberman, Osvaldo Berger, Pablo Sabat, Victor Velasquez, Enzo Castiglione, Margarita Calonge
PURPOSE: To characterize the clinical features in patients with presumed ocular tuberculosis (TB) and determine prognostic factors of visual outcomes and complications in this disease. MATERIAL AND METHODS: Retrospective case series of 35 patients (29 females, 6 males) with presumed ocular TB from referral centers in Chile and Spain between 2002 and 2012. Medical records were reviewed, and data regarding clinical features, complications, best-corrected visual acuity (BCVA), duration of disease, extraocular manifestations, and therapy were retrieved...
February 3, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28157410/short-term-vitreoretinal-tamponade-with-heavy-liquid-following-surgery-for-giant-retinal-tear
#2
Maya Eiger-Moscovich, Assaf Gershoni, Ruth Axer-Siegel, Dov Weinberger, Rita Ehrlich
PURPOSE: To study the efficacy and outcomes of short-term postoperative vitreoretinal tamponade with perfluorocarbon heavy liquid in patients with giant retinal tear. MATERIALS AND METHODS: The study group consisted of 13 consecutive patients (13 eyes) who presented with giant retinal tear at a tertiary medical center in 2011-2015 and were treated with vitrectomy followed by short-term tamponade with perfluorocarbon heavy liquid. A minimum of 3 months' follow-up was required for inclusion...
February 3, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28139163/comparison-of-autologous-serum-versus-preservative-free-artificial-tear-in-patients-with-dry-eyes-due-to-systemic-isotretinoin-therapy
#3
Uğur Yılmaz, Erkut Küçük, Çağdaş Koç, Enes Gökler
PURPOSE: To investigate dry eye development in the patients receiving systemic retinoic acid therapy and to compare effectiveness of Autologous Serum (AS) and preservative free artificial tear (PFAT) in the patients with dry eye disease. METHOD: This prospective, crossover, double blind study was conducted on patients who have dry eyes due to systemic isotretinoin treatment for different indications. Patients detected as having dry eye during systemic isotretinoin treatment were included to our study...
January 31, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28139159/light-induced-retinopathy-young-age-protects-more-than-ocular-pigmentation
#4
Anna Polosa, Hyba Bessaklia, Pierre Lachapelle
PURPOSE: The purpose of this study was to compare the efficacy that ocular melanin confers in protecting the retina of juvenile and adult rats exposed to a bright luminous environment. METHODS: Juvenile (JLE) and adult (ALE) Long-Evans pigmented rats were thus exposed to a bright cyclic light (10,000lux; white light) from postnatal day 14-28 or for 6 consecutive days, respectively. Flash electroretinograms (ERG) and retinal histology were performed at different predetermined ages, post-light exposure...
January 31, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28139154/safety-and-efficacy-of-a-membrane-tube-type-glaucoma-shunt-device-an-animal-trial
#5
Dai Woo Kim, Young Hoon Hwang, Byung Heon Ahn, Eun-Kyung Lee, Chang-Sik Kim
PURPOSE: To evaluate the safety and efficacy of a membrane-tube-type glaucoma shunt device (MT-device), which was developed to control intraocular pressure (IOP) with a lower chance of complications than conventional glaucoma surgery, in a rabbit model. MATERIALS AND METHODS: The MT-device consists of an expanded polytetrafluoroethylene membrane (thickness 0.2 mm, area 2.5 × 2.5 mm(2)) and a tube (internal diameter 76 µm, external diameter 175.5 µm, length 7 mm) attached to the membrane...
January 31, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28139150/efficacy-of-purtscher-s-retinopathy-treatments-a-systematic-review
#6
Duosheng Xia, Xiaomei Chen, Qi Zhou, Shujun Xiao, Yang Yu, Yadong Wang, Gang Du, Haixiang Huang, Wenfang Zhang, Yaolong Chen
OBJECTIVE: The aim of this review is to evaluate the efficacy of available Purtscher's Retinopathy treatments. MATERIALS AND METHODS: In order to collect single-case reports, electronic searches were conducted in several databases including PubMed, Embase, Web of Science, China National Knowledge Infrastructure, SinoMed, VIP, and WanFang in the Electronic Theses and Dissertations Center. In VIP and Wanfang, we also traced the references of included articles. Risk of bias was evaluated using a tool adapted from the Cochrane Risk of Bias Tool...
January 31, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28139142/relation-between-ocular-comfort-arachidonic-acid-mediators-and-histamine
#7
Simin Masoudi, Zhenjun Zhao, Mark Willcox
PURPOSE: Contact lenses are associated with discomfort during wear. This may be the result of stimulation of the ocular surface and production of pro-inflammatory mediators which are then released into the tears. This study examined changes in the concentration in tears of arachidonic acid metabolites (AAM) prostaglandins, cysteinyl leukotrienes, and resolvin-D1, as well as histamine in a general contact lens population in the morning and evening. METHOD: Tears were collected twice a day (morning and evening) for up to 10 days on two different occasions (with and without contact lens wear) from 30 experienced contact lens wearers for analysis of AAM and a separate group (N = 33) for analysis of histamine...
January 31, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28129001/association-between-migraine-and-dry-eye-disease-a-nationwide-population-based-study
#8
Soonwon Yang, Woojun Kim, Hyun Seung Kim, Kyung-Sun Na
PURPOSE: Despite the possible association between migraine and dry eye disease (DED), there are only a few studies investigating this link in a relatively limited number of patients. Therefore, we have analyzed the relationship between migraine and DED in the Korean population. MATERIALS AND METHODS: This population-based cross-sectional study included 14 329 adults participating in the fifth annual Korea National Health and Nutrition Examination Survey from 2010 to 2012...
January 27, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28129000/dry-eye-symptoms-patient-reported-visual-functioning-and-health-anxiety-influencing-patient-satisfaction-after-cataract-surgery
#9
Ildikó Szakáts, Margit Sebestyén, Éva Tóth, György Purebl
PURPOSE: To evaluate how patient satisfaction after cataract surgery is associated with postoperative visual acuity, visual functioning, dry eye signs and symptoms, health anxiety, and depressive symptoms. PATIENTS AND METHODS: Fifty-four patients (mean age: 68.02 years) were assessed 2 months after uneventful phacoemulsification; 27 were unsatisfied with their postoperative results and 27 were satisfied. They completed the following questionnaires: Visual Function Index-14 (VF-14), Ocular Surface Disease Index (OSDI), Shortened Health Anxiety Inventory (SHAI), and Shortened Beck Depression Inventory...
January 27, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28128997/roasting-enhances-the-anti-cataract-effect-of-coffee-beans-ameliorating-selenite-induced-cataracts-in-rats
#10
Nana Ishimori, Jun Oguchi, Yosuke Nakazawa, Kenji Kobata, Megumi Funakoshi-Tago, Hiroomi Tamura
PURPOSE: Coffee is a widely consumed beverage. While recent studies have linked its intake to a reduced risk of cataracts, caffeine is believed to be the key factor for its effect. To know how roasting beans affects the effect of coffee on cataract formation, we investigated the impact roasting using a selenite-induced cataract rat model. MATERIALS AND METHODS: Sprague Dawley rats were given a single injection of sodium selenite, which induced formation of nuclear cataracts by day 6, with or without coffee intake (100% coffee, 0...
January 27, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28128986/comparison-of-intravitreal-bevacizumab-intravitreal-ranibizumab-and-laser-photocoagulation-for-treatment-of-type-1-retinopathy-of-prematurity-in-turkish-preterm-children
#11
Emrah Utku Kabataş, Bengi Ece Kurtul, Pınar Altıaylık Özer, Naciye Kabataş
PURPOSE: To evaluate effectiveness of treatment modalities, major complications and refractive errors in children who were treated with intravitreal bevacizumab (IVB), intravitreal ranibizumab (IVR) or laser photocoagulation (LP) for type 1 retinopathy of prematurity (ROP). METHODS: Premature infants who underwent IVB monotherapy (Group 1), IVR monotherapy (Group 2) or LP (Group 3) for type 1 ROP and infants with spontaneously regressed ROP (Group 4) were included for the study...
January 27, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28128981/development-and-assessment-of-a-novel-canine-ex-vivo-corneal-model
#12
Laura R Proietto, R David Whitley, Dennis E Brooks, Gregory E Schultz, Daniel J Gibson, William M Berkowski, Marc E Salute, Caryn E Plummer
PURPOSE: To develop a novel ex vivo extended culture model of canine corneal epithelial cell wound healing. MATERIALS AND METHODS: Canine corneoscleral rims (CSR) were obtained and, after preparation for culture, were placed on a nutating scaffold and incubated in physiological conditions. In experiment 1, eight CSR in a serum-containing antimicrobial-fortified medium were monitored for epithelial integrity and bacterial infection up to 28 days in culture. CSR were assessed histologically at the end of the culture period end points 0, 7, 14, and 28 days with accompanying scanning electron microscopic (SEM) and transmission electron microscopic (TEM) evaluation...
January 27, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28121186/goldmann-applanation-tonometry-versus-dynamic-contour-tonometry-after-vitrectomy-with-silicone-oil-endotamponade
#13
Matthias Fuest, Nikolaos Mamas, Peter Walter, Babac E Mazinani, Gemot Roessler, Niklas Plange
PURPOSE: To evaluate the agreement of intraocular pressure (IOP) measurements using dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) in eyes after vitrectomy with silicone oil endotamponade and controls. METHODS: In this prospective comparative study, IOP was measured with GAT and DCT in 30 eyes with oil endotamponade 1-3 days after vitrectomy and 40 untreated controls. In addition, ocular pulse amplitude (OPA), corneal pachymetry (CCT), and axial length (AL) were measured...
January 25, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28121176/macular-choroidal-thickness-may-be-the-earliest-determiner-to-detect-the-onset-of-diabetic-retinopathy-in-patients-with-prediabetes-a-prospective-and-comparative-study
#14
Serpil Yazgan, Dilek Arpaci, Haci Ugur Celik, Mustafa Dogan, Irem Isık
PURPOSE: To evaluate the macular and peripapillary choroidal thickness and retinal volume in prediabetes. MATERIAL AND METHODS: This prospective comparative study included 53 patients with prediabetes and 53 age- and sex-matched healthy subjects. Only right eyes were selected. Choroidal thicknesses (CT) and retinal volume were measured by optical coherence tomography. Macular CT was measured at the seven points including macular center, 1, 2, and 3 mm distances along the temporal and nasal scans...
January 25, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28121174/the-role-of-beta-adrenergic-receptors-in-the-regulation-of-circadian-intraocular-pressure-rhythm-in-mice
#15
Shunsuke Tsuchiya, Tomomi Higashide, Kazunori Toida, Kazuhisa Sugiyama
PURPOSE: To investigate whether the elimination of β1- and β2-adrenergic receptors alters the diurnal intraocular pressure (IOP) rhythm in mice. MATERIALS AND METHODS: β1-/β2-adrenergic receptor double-knockout and C57BL/6J mice were anesthetized intraperitoneally, with their IOPs measured via microneedle method. After entrainment to a 12-h light-dark (LD) cycle (light phase 6:00-18:00), IOPs were measured every 3 h from 9:00 to 24:00 (group 1, β1-/β2-adrenergic receptor double-knockout mice, n = 11; C57BL/6J, n = 15)...
January 25, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28118055/the-role-of-mitochondria-oxidative-stress-and-the-radical-binding-protein-a1m-in-cultured-porcine-retina
#16
Bo Åkerström, Martin Cederlund, Jesper Bergwik, Oscar Manouchehrian, Karin Arnér, Ingrid Holmgren Taylor, Fredrik Ghosh, Linnéa Taylor
PURPOSE: The purpose of this study was to explore the relationship between oxidative stress, antioxidant defense, mitochondrial structure, and biomechanical tissue support in the isolated porcine retina. METHODS: Full-thickness retinal sheets were isolated from adult porcine eyes. Retinas were cultured for 2 or 48 h using (1) a previously established low-support explant protocol with photoreceptors positioned against the culture membrane (porous polycarbonate) or (2) a high-support procedure developed by our group, apposing the Müller cell endfeet and inner limiting membrane against the membrane...
January 24, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28118054/prediction-of-changes-in-visual-acuity-and-contrast-sensitivity-function-by-tissue-redness-after-pterygium-surgery
#17
Mohd Radzi Hilmi, Mohd Zulfaezal Che Azemin, Khairidzan Mohd Kamal, Mohd Izzuddin Mohd Tamrin, Norfazrina Abdul Gaffur, Tengku Mohd Tengku Sembok
PURPOSE: The goal of this study was to predict visual acuity (VA) and contrast sensitivity function (CSF) with tissue redness grading after pterygium surgery. MATERIALS AND METHODS: A total of 67 primary pterygium participants were selected from patients who visited an ophthalmology clinic. We developed a semi-automated computer program to measure the pterygium fibrovascular redness from digital pterygium images. The final outcome of this software is a continuous scale grading of 1 (minimum redness) to 3 (maximum redness)...
January 24, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28095050/the-expressions-of-klotho-family-genes-in-human-ocular-tissues-and-in-anterior-lens-capsules-of-age-related-cataract
#18
Yu Zhang, Liya Wang, Zhong Wu, Xiaolin Yu, Xiaofeng Du, Xiaohua Li
PURPOSE: Klotho genes are expressed in limited tissues and have been found to be a pathogenic factor of age-related diseases in mammals, but their expressions and functions in human eyes are yet to be defined. This study was performed to investigate the expression of Klotho family genes in human ocular tissues and anterior lens capsules of age-related cataract. METHODS: Individual tissues were isolated from human eyeballs collected from Henan Eye Bank. Human anterior lens capsules were collected from cortical cataract patients during phacoemulsification with the informed consent...
January 17, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28094585/relationship-between-plasma-homocysteine-level-and-glaucomatous-retinal-nerve-fiber-layer-defect
#19
Jae Yeun Lee, Joon Mo Kim, In Tae Kim, Chung Kwon Yoo, Yu Sam Won, Jung Hoon Kim, Hyun Seok Kwon, Ki Ho Park
AIMS: To investigate the association between plasma homocysteine levels and glaucomatous retinal nerve fiber layer (RNFL) defect in South Korean population. MATERIALS AND METHODS: This retrospective cross-sectional study included subjects who underwent screening at Kangbuk Samsung Hospital Health Screening Center between August 2012 and July 2013. Subjects underwent physical examination and provided samples for laboratory analysis of homocysteine. Subjects were divided equally into four quartiles (Qs) based on plasma homocysteine level...
January 17, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28094584/cytoskeletal-alteration-and-change-of-retinal-nerve-fiber-layer-birefringence-in-hypertensive-retina
#20
Xiang-Run Huang, Robert W Knighton, Ye Z Spector, William J Feuer
PURPOSE: Glaucoma damages the retinal nerve fiber layer (RNFL). Both RNFL thickness and retardance can be used to assess the damage, but birefringence, the ratio of retardance to thickness, is a property of the tissue itself. This study investigated the relationship between axonal cytoskeleton and RNFL birefringence in retinas with hypertensive damage. MATERIALS AND METHODS: High intraocular pressure (IOP) was induced unilaterally in rat eyes. RNFL retardance in isolated retinas was measured...
January 17, 2017: Current Eye Research
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