journal
MENU ▼
Read by QxMD icon Read
search

Journal of Clinical Immunology

journal
https://www.readbyqxmd.com/read/28332028/infection-profile-in-chronic-granulomatous-disease-a-23-year-experience-from-a-tertiary-care-center-in-north-india
#1
Amit Rawat, Pandiarajan Vignesh, Avinash Sharma, Jitendra K Shandilya, Madhubala Sharma, Deepti Suri, Anju Gupta, Vikas Gautam, Pallab Ray, Shivaprakash M Rudramurthy, Arunaloke Chakrabarti, Kohsuke Imai, Shigeaki Nonoyama, Osamu Ohara, Yu L Lau, Surjit Singh
PURPOSE: Chronic granulomatous disease (CGD) is an inherited phagocytic disorder characterized by recurrent infections with usually catalase-positive organisms. Infections in CGD from developing countries are expected to be different from those in the Western countries. We report the profile of infections in children diagnosed with CGD from a tertiary care center in North India. METHODOLOGY: Case records of children diagnosed with CGD at Pediatric Immunodeficiency Clinic, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India, from August 1993 to April 2016 (23 years) were analyzed...
March 22, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28321612/serial-serum-immunoglobulin-g-igg-trough-levels-in-patients-with-x-linked-agammaglobulinemia-on-replacement-therapy-with-intravenous-immunoglobulin-its-correlation-with-infections-in-indian-children
#2
Deepti Suri, Sagar Bhattad, Avinash Sharma, Anju Gupta, Amit Rawat, Shobha Sehgal, Surjit Singh, Sudhir Gupta
Patients with primary antibody deficiency (PAD) are being increasingly diagnosed in the developing world. However, care of these children continues to remain suboptimal due to financial and social constraints. Immunoglobulin (Ig) trough level is an important predicting factor for infections in children on replacement immunoglobulin therapy. There are no data on this aspect from the developing world. Therefore, we studied serial immunoglobulin G (IgG) trough levels in 14 children with X-linked agammaglobulinemia (XLA) receiving replacement intravenous immunoglobulin (IVIG)...
March 21, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28316003/evaluation-of-the-safety-tolerability-and-pharmacokinetics-of-gammaplex-%C3%A2-10-versus-gammaplex-%C3%A2-5-in-subjects-with-primary-immunodeficiency
#3
Richard L Wasserman, Isaac R Melamed, Mark R Stein, Stephen Jolles, Miranda Norton, James N Moy
PURPOSE: This phase 3, multicenter, open-label, randomized, two-period, crossover bioequivalence trial evaluated the safety, tolerability, and pharmacokinetics of intravenous immunoglobulins (IVIGs) Gammaplex 5% and Gammaplex 10% in 33 adults and 15 children with primary immunodeficiency diseases (PIDs). METHODS: Eligible adults received five Gammaplex 5% infusions followed by five Gammaplex 10% infusions, or vice versa, stratified by a 21- or 28-day dosing regimen...
March 18, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28303442/different-immunological-pathways-underlie-the-immune-response-to-pneumococcal-polysaccharides
#4
LETTER
Leen Moens, Capucine Picard, Mohammad Shahrooei, Greet Wuyts, Adrian Liston, Alain Fischer, Xavier Bossuyt
No abstract text is available yet for this article.
March 16, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28299599/incidence-of-typically-severe-primary-immunodeficiency-diseases-in-consanguineous-and-non-consanguineous-populations
#5
Arnon Broides, Amit Nahum, Amarilla B Mandola, Lihi Rozner, Vered Pinsk, Galina Ling, Baruch Yerushalmi, Jacov Levy, Noga Givon-Lavi
PURPOSE: Primary immunodeficiency diseases are considered to be rare diseases; however, data on the exact birth incidences of these diseases are sparse. Southern Israel is inhabited by two major populations: a relatively non-consanguineous Jewish population and a highly consanguineous Muslim Bedouin population. We sought to calculate the incidences of typically severe primary immunodeficiency diseases and compare the incidences in these populations. METHODS: A retrospective analysis of all typically severe primary immunodeficiency diseases evaluated at a single center from January 1, 1996 to December 31, 2016...
March 16, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28293897/low-iga-and-igm-is-associated-with-a-higher-prevalence-of-bronchiectasis-in-primary-antibody-deficiency
#6
LETTER
John P Hodkinson, Catherine Bangs, Andrea Watenberg-Demand, Artur Bauhofer, Patrick Langohr, Matthew S Buckland, David Guzman, Patrick F K Yong, Sorena Kiani-Alikhan
No abstract text is available yet for this article.
March 14, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28265964/rescue-of-cytokine-storm-due-to-hlh-by-hemoadsorption-in-a-ctla4-deficient-patient
#7
LETTER
Christine Greil, Fabian Roether, Paul La Rosée, Bodo Grimbacher, Daniel Duerschmied, Klaus Warnatz
No abstract text is available yet for this article.
March 6, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28236219/gastrointestinal-manifestations-in-x-linked-agammaglobulinemia
#8
Sara Barmettler, Iris M Otani, Jasmit Minhas, Roshini S Abraham, Yenhui Chang, Morna J Dorsey, Zuhair K Ballas, Francisco A Bonilla, Hans D Ochs, Jolan E Walter
PURPOSE: X-linked agammaglobulinemia is a primary humoral immunodeficiency characterized by hypogammaglobulinemia and increased susceptibility to infection. Although there is increased awareness of autoimmune and inflammatory complications in X-linked agammaglobulinemia (XLA), the spectrum of gastrointestinal manifestations has not previously been fully explored. METHODS: We present a case report of a family with two affected patients with XLA. Given the gastrointestinal involvement of the grandfather in this family, we performed a retrospective descriptive analysis of XLA patients with reported diagnoses of GI manifestations and inflammatory bowel disease (IBD) or enteritis registered at the United States Immunodeficiency Network, a national registry of primary immunodeficiencies...
February 24, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28224354/a-stable-mixed-chimera-after-sct-with-ric-in-an-infant-with-i%C3%AE%C2%BAb%C3%AE-hypermorphic-mutation
#9
LETTER
Masayuki Nagasawa, Teppei Ohkawa, Masatoshi Takagi, Kohsuke Imai, Tomohiro Morio
No abstract text is available yet for this article.
February 21, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28224353/diagnosis-of-interstitial-lung-disease-caused-by-possible-hypersensitivity-pneumonitis-in-a-child-think-cgd
#10
LETTER
Saliha Esenboga, Nagehan Emiralioglu, Deniz Cagdas, Baran Erman, Martin De Boer, Berna Oguz, Nural Kiper, İlhan Tezcan
Interstitial lung disease (ILD) is a rare and heterogeneous group of disorder affecting the lung parenchyma and has a detrimental effect on gas exchange. Chronic granulomatous disease (CGD), when it affects primarily lungs, may cause ILD. We report a 16-year-old patient with CGD caused by homozygous deletion of NCF1 who atypically presented with ILD. The patient had many pigeons and was a pigeon breeder. Exacerbated clinical symptoms were linked to hypersensitivity pneumonitis (HP), and the patient was suggested to keep away from pigeons...
February 21, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28194615/how-we-manage-adenosine-deaminase-deficient-severe-combined-immune-deficiency-ada-scid
#11
Donald B Kohn, H Bobby Gaspar
Adenosine deaminase-deficient severe combined immune deficiency (ADA SCID) accounts for 10-15% of cases of human SCID. From what was once a uniformly fatal disease, the prognosis for infants with ADA SCID has improved greatly based on the development of multiple therapeutic options, coupled with more frequent early diagnosis due to implementation of newborn screening for SCID. We review the various treatment approaches for ADA SCID including allogeneic hematopoietic stem cell transplantation (HSCT) from a human leukocyte antigen-matched sibling or family member or from a matched unrelated donor or a haplo-identical donor, autologous HSCT with gene correction of the hematopoietic stem cells (gene therapy-GT), and enzyme replacement therapy (ERT) with polyethylene glycol-conjugated adenosine deaminase...
February 14, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28236086/case-studies
#12
Ralph S Shapiro, Richard L Wasserman, Vincent Bonagura, Sudhir Gupta
No abstract text is available yet for this article.
February 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28236085/supplement-frontiers-in-immunoglobulin-therapy-of-primary-immunodeficiency-disease
#13
EDITORIAL
Ralph S Shapiro
No abstract text is available yet for this article.
February 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28197791/clinical-manifestations-and-genetic-analysis-of-17-patients-with-autosomal-dominant-hyper-ige-syndrome-in-mainland-china-new-reports-and-a-literature-review
#14
Jing Wu, Ji Chen, Zhi-Qing Tian, Hao Zhang, Ruo-Lan Gong, Tong-Xin Chen, Li Hong
PURPOSE: Autosomal dominant hyper-IgE syndrome (AD-HIES) is a rare complicated primary immunodeficiency disease (PID). Signal transducer and activator of transcription 3 (STAT3) gene mutation is found to cause AD-HIES. The distribution of AD-HIES patients with STAT3 deficiency in the Chinese population is not clear. Herein, we retrospectively report 17 AD-HIES patients with STAT3 deficiency and demonstrate their clinical, immunological, and genetic features. METHODS: Patients' clinical data were collected from their medical records...
February 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28188499/2017-cis-annual-meeting-immune-deficiency-dysregulation-north-american-conference
#15
(no author information available yet)
No abstract text is available yet for this article.
February 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28160239/impact-of-site-of-care-on-infection-rates-among-patients-with-primary-immunodeficiency-diseases-receiving-intravenous-immunoglobulin-therapy
#16
Richard L Wasserman, Diane Ito, Yan Xiong, Xiaolan Ye, Patrick Bonnet, Josephine Li-McLeod
PURPOSE: Patients with primary immunodeficiency diseases (PIDD) are at increased risk of infection and may require lifelong immunoglobulin G (IgG) replacement. Infection incidence rates were determined for patients with PIDD receiving intravenously administered IgG (IGIV) in a home or hospital outpatient infusion center (HOIC). METHODS: Data were extracted from a large, US-based, employer-sponsored administrative database. Patients were eligible for analysis if they had ≥1 inpatient or emergency room claim or ≥2 outpatient claims with a PIDD diagnosis between January 2002 and March 2013, 12 months of continuous health plan enrollment prior to index date (i...
February 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28130637/respiratory-complications-lead-to-the-diagnosis-of-chronic-granulomatous-disease-in-two-adult-patients
#17
LETTER
Sylvie Colin de Verdière, Esther Noel, Claire Lozano, Emilie Catherinot, Mickael Martin, Elisabeth Rivaud, Louis-Jean Couderc, Hélène Salvator, Jacinta Bustamante, Thierry Martin
Chronic granulomatous disease (CGD) is a primary immunodeficiency associated to multiple life-threatening bacterial and fungal infections, beginning in childhood. There are rare cases of diagnosis in adulthood. We describe here two cases of late diagnosis in adults: a 45-year-old woman and 59-year-old-man. CGD diagnosis should be considered in adult patients with unexplained infectious diseases with tissue granuloma.
February 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28127684/erratum-to-increased-mucosal-il-22-production-of-an-il-10ra-mutation-patient-following-anakinra-treatment-suggests-further-mechanism-for-mucosal-healing
#18
Jian Li, Dror S Shouval, Andria L Doty, Scott B Snapper, Sarah C Glover
No abstract text is available yet for this article.
February 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28124237/increased-incidence-of-fatigue-in-patients-with-primary-immunodeficiency-disorders-prevalence-and-associations-within-the-us-immunodeficiency-network-registry
#19
Joud Hajjar, Danielle Guffey, Charles G Minard, Jordan S Orange
INTRODUCTION: Patients with primary immunodeficiency (PID) often report fatigue, yet this symptom has not been studied in PID. Fatigue affects 6-7.5% of healthy adults. The goal of this study is to estimate the prevalence of fatigue in patients with PID and investigate its associated factors. METHODS: We analyzed 2537 PID patients registered in USIDNET to determine responses to the field "fatigue" in the core registry form. Demographics, immune phenotypes, and comorbid conditions were compared between fatigued and non-fatigued patients to identify relevant associations and potential drivers...
February 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28064389/increased-mucosal-il-22-production-of-an-il-10ra-mutation-patient-following-anakinra-treatment-suggests-further-mechanism-for-mucosal-healing
#20
LETTER
Jian Li, Dror S Shouval, Andria L Doty, Scott B Snapper, Sarah C Glover
No abstract text is available yet for this article.
February 2017: Journal of Clinical Immunology
journal
journal
28117
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"