journal
MENU ▼
Read by QxMD icon Read
search

Journal of Clinical Immunology

journal
https://www.readbyqxmd.com/read/28639167/azathioprine-associated-complete-nk-cell-deficiency
#1
LETTER
Amir B Orandi, Tiphanie P Vogel, Molly P Keppel, Elizabeth C Utterson, Megan A Cooper
No abstract text is available yet for this article.
June 22, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28639166/ifn%C3%A9-block-treosulfan-conditioning-and-%C3%AE-%C3%AE-t-cell-deplete-pbsct-for-xiap-deficient-hlh
#2
LETTER
Ciara O'Rafferty, Mark Velangi, Sarah Lawson, Prashant Hiwarkar, Jayashree Motwani
No abstract text is available yet for this article.
June 21, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28631025/diverse-autoantibody-reactivity-in-cartilage-hair-hypoplasia
#3
LETTER
Catherine M Biggs, Svetlana Kostjukovits, Kerry Dobbs, Saila Laakso, Paula Klemetti, Helena Valta, Mervi Taskinen, Outi Mäkitie, Luigi D Notarangelo
No abstract text is available yet for this article.
June 19, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28624913/persistent-skin-pouches-following-subcutaneous-immunoglobulin-infusions-in-a-girl-with-immunodeficiency-bullous-skin-lesions-and-melanosis-oculi
#4
LETTER
Renate Krüger, Cornelia Feiterna-Sperling, Ulrike Blume-Peytavi, Birgit Lala, Horst von Bernuth, Volker Wahn
No abstract text is available yet for this article.
June 17, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28601916/thyroid-carcinoma-in-a-child-with-activated-phosphoinositide-3-kinase-%C3%AE-syndrome-somatic-effect-of-a-germline-mutation
#5
LETTER
Giorgia Bucciol, Lien Willems, Esther Hauben, Anne Uyttebroeck, Marijke Proesmans, Isabelle Meyts
No abstract text is available yet for this article.
June 11, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28597146/human-i%C3%AE%C2%BAb%C3%AE-gain-of-function-a-severe-and-syndromic-immunodeficiency
#6
REVIEW
Bertrand Boisson, Anne Puel, Capucine Picard, Jean-Laurent Casanova
Germline heterozygous gain-of-function (GOF) mutations of NFKBIA, encoding IκBα, cause an autosomal dominant (AD) form of anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID). Fourteen unrelated patients have been reported since the identification of the first case in 2003. All mutations enhanced the inhibitory activity of IκBα, by preventing its phosphorylation on serine 32 or 36 and its subsequent degradation. The mutation certainly or probably occurred de novo in 13 patients, whereas it was inherited from a parent with somatic mosaicism in one patient...
June 9, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28597145/quality-of-life-treatment-beliefs-and-treatment-satisfaction-in-children-treated-for-primary-immunodeficiency-with-scig
#7
Serge Sultan, Émélie Rondeau, Marie-Claude Levasseur, Renée Dicaire, Hélène Decaluwe, Élie Haddad
Despite the development of subcutaneous treatment, children and adolescents with primary immunodeficiency (PID) are vulnerable to a lower quality of life (QoL) than non-clinical participants. Comparisons have been offered in rare reports with limited sample sizes. No description is available of treatment beliefs and treatment satisfaction with standard tools. The objective of this study was to describe a large sample of patients with pediatric PID on QoL, treatment beliefs and satisfaction, and identify perceived benefits and issues of treatment both in children and parents...
June 8, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28597144/multicolor-flow-cytometry-for-the-diagnosis-of-primary-immunodeficiency-diseases
#8
Takehiro Takashima, Miko Okamura, Tzu-Wen Yeh, Tsubasa Okano, Motoi Yamashita, Keisuke Tanaka, Akihiro Hoshino, Noriko Mitsuiki, Masatoshi Takagi, Eiichi Ishii, Kohsuke Imai, Hirokazu Kanegane, Tomohiro Morio
PURPOSE: Primary immunodeficiency diseases (PIDDs) are rare inherited diseases that impair the human immune system. We established a multicolor flow cytometric assay to comprehensively evaluate the immune status and immunological characteristics of patients with PIDDs. METHODS: Fifty-nine normal controls and 75 patients with PIDDs, including X-linked severe combined immunodeficiency (X-SCID), X-linked agammaglobulinemia (XLA), X-linked hyper IgM syndrome (X-HIGM), ataxia telangiectasia (AT), Wiskott-Aldrich syndrome (WAS), hyper IgE syndrome (HIES), and chronic mucocutaneous candidiasis disease (CMCD), were enrolled in this study...
June 8, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28589420/the-use-of-salmonella-typhim-vaccine-to-diagnose-antibody-deficiency
#9
Mary T Bausch-Jurken, James W Verbsky, Katherine A Gonzaga, Nancy P Elms, Mary K Hintermeyer, Stephen B Gauld, John M Routes
PURPOSE: The specific antibody response to the unconjugated 23-valent pneumococcal polysaccharide vaccine is one of the most common tests used to assess for possible humoral immunodeficiency. The results can be difficult to interpret because most people have been immunized with one or more of the pneumococcal vaccines and there is controversy regarding what constitutes a normal response. To circumvent this problem, we developed an ELISA to measure IgG-specific antibodies to the Salmonella Vi Typhim (S...
June 7, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28540525/identification-of-22q11-2-deletion-syndrome-via-newborn-screening-for-severe-combined-immunodeficiency
#10
Jessica C Barry, Terrence Blaine Crowley, Soma Jyonouchi, Jennifer Heimall, Elaine H Zackai, Kathleen E Sullivan, Donna M McDonald-McGinn
PURPOSE: Chromosome 22q11.2 deletion syndrome (22q11.2DS), the most common cause of DiGeorge syndrome, is quite variable. Neonatal diagnosis traditionally relies on recognition of classic features and cytogenetic testing, but many patients come to attention only following identification of later onset conditions, such as hypernasal speech due to palatal insufficiency and developmental and behavioral differences including speech delay, autism, and learning disabilities that would benefit from early interventions...
May 24, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28536745/health-related-quality-of-life-in-adult-patients-with-common-variable-immunodeficiency-disorders-and-impact-of-treatment
#11
Nicholas L Rider, Carleigh Kutac, Joud Hajjar, Chris Scalchunes, Filiz O Seeborg, Marcia Boyle, Jordan S Orange
PURPOSE: Common variable immunodeficiency disorder (CVID) is a primary immunodeficiency disease (PIDD) often associated with severe and chronic infections. Patients commonly receive immunoglobulin (Ig) treatment to reduce the cycle of recurrent infection and improve physical functioning. However, how Ig treatment in CVID affects quality of life (QOL) has not been thoroughly evaluated. The purpose of a recent Immune Deficiency Foundation (IDF) mail survey was to assess the factors that are associated with QOL in patients with CVID receiving Ig treatment...
May 23, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28523402/advances-in-the-care-of-primary-immunodeficiencies-pids-from-birth-to-adulthood
#12
Nizar Mahlaoui, Klaus Warnatz, Alison Jones, Sarita Workman, Andrew Cant
Primary immunodeficiencies (PIDs) are a widely heterogeneous group of inherited defects of the immune system consisting of many clinical phenotypes with at least 300 underlying genetic deficits currently known. Patients with PIDs can present with, or develop during the course of their life, a susceptibility to recurrent and chronic infection along with autoimmune, allergic, inflammatory, and/or proliferative disorders, all potentially leading to end-organ damage. In recent years, a combination of basic and clinical research has greatly improved understanding of the underlying immunological and genetic defects in PIDs, leading to improved diagnosis, classification, and treatment approaches...
May 18, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28508932/enterovirus-related-immune-reconstitution-inflammatory-syndrome-iris-following-haploidentical-stem-cell-transplantation-in-an-mhc-class-ii-deficient-child
#13
LETTER
Ravi M Shah, Sheila Waugh, Khuen F Ng, Andrew R Gennery, Mary Slatter, Andrew J Cant
No abstract text is available yet for this article.
May 16, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28503715/deficiency-of-interleukin-1-receptor-antagonist-dira-report-of-the-first-indian-patient-and-a-novel-deletion-affecting-il1rn
#14
Leonardo O Mendonca, Louise Malle, Frank X Donovan, Settara C Chandrasekharappa, Gina A Montealegre Sanchez, Megha Garg, Ulf Tedgard, Mariana Castells, Shiv S Saini, Sourabh Dutta, Raphaela Goldbach-Mansky, Deepti Suri, Adriana A Jesus
PURPOSE: Deficiency of interleukin-1 receptor antagonist (DIRA) is a rare life-threatening autoinflammatory disease caused by autosomal recessive mutations in IL1RN. DIRA presents clinically with early onset generalized pustulosis, multifocal osteomyelitis, and elevation of acute phase reactants. We evaluated and treated an antibiotic-unresponsive patient with presumed DIRA with recombinant IL-1Ra (anakinra). The patient developed anaphylaxis to anakinra and was subsequently desensitized...
May 15, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28493158/common-variable-immunodeficiency-caused-by-fanc-mutations
#15
Yujin Sekinaka, Noriko Mitsuiki, Kohsuke Imai, Miharu Yabe, Hiromasa Yabe, Kanako Mitsui-Sekinaka, Kenichi Honma, Masatoshi Takagi, Ayako Arai, Kenichi Yoshida, Yusuke Okuno, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Hideki Muramatsu, Seiji Kojima, Asuka Hira, Minoru Takata, Osamu Ohara, Seishi Ogawa, Tomohiro Morio, Shigeaki Nonoyama
Common variable immunodeficiency (CVID) is the most common adult-onset primary antibody deficiency disease due to various causative genes. Several genes, which are known to be the cause of different diseases, have recently been reported as the cause of CVID in patients by performing whole exome sequencing (WES) analysis. Here, we found FANC gene mutations as a cause of adult-onset CVID in two patients. B cells were absent and CD4(+) T cells were skewed toward CD45RO(+) memory T cells. T-cell receptor excision circles (TRECs) and signal joint kappa-deleting recombination excision circles (sjKRECs) were undetectable in both patients...
May 11, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28417298/disseminated-mycobacterium-malmoense-and-salmonella-infections-associated-with-a-novel-variant-in-nfkbia
#16
LETTER
Emily Staples, Beatriz Morillo-Gutierrez, Jessica Davies, Daniel Petersheim, Michel Massaad, Mary Slatter, Dimitra Dimou, Rainer Doffinger, Scott Hackett, Dinkantha Kumararatne, James Hadfield, Matthew D Eldridge, Raif S Geha, Mario Abinun, James E D Thaventhiran
No abstract text is available yet for this article.
April 17, 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28488145/anti-pneumococcal-vaccine-induced-cellular-immune-responses-in-post-traumatic-splenectomized-individuals
#17
Djursun Karasartova, Umut Gazi, Ozgur Tosun, Ayse S Gureser, Ibrahim T Sahiner, Mete Dolapci, Aysegul T Ozkan
PURPOSE: Splenectomy is associated with increased risk of overwhelming post-splenectomy infections despite proper anti-pneumococcal vaccination. As most studies concentrated on vaccination-induced humoral immunity, the cellular immune responses triggered in splenectomized patients are not yet well studied. The present study aims to investigate this area as it can contribute to the development of more effective vaccination strategies. METHODS: Five healthy and 14 splenectomized patients were vaccinated with pneumococcal conjugate polysaccharide vaccine (PCV) followed by pneumococcal polysaccharide vaccine according to the guidelines established by Advisory Committee on Immunization Practices...
May 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28484900/diagnostic-delay-of-primary-immunodeficiencies-at-a-tertiary-care-hospital-in-peru-brief-report
#18
Liz E Veramendi-Espinoza, Jessica H Zafra-Tanaka, Gabriela A Pérez-Casquino, Wilmer O Córdova-Calderón
OBJECTIVE: The aim of the study was to assess the diagnostic delay in pediatric patients with primary immunodeficiencies (PID) at a tertiary care hospital in Peru. METHODS: A descriptive study was carried out in which patients from a third-level referral center in Peru were included. Those without a specific diagnosis of PID were excluded. Data was collected by reviewing the medical records and interviewing patients' family members. RESULTS: A total of 45 patients with a mean of 7...
May 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28432485/persistent-impairment-of-t-cell-regeneration-in-a-patient-with-activated-pi3k-%C3%AE-syndrome
#19
LETTER
Fumihiro Goto, Toru Uchiyama, Yumiko Nakazawa, Kohsuke Imai, Toshinao Kawai, Masafumi Onodera
No abstract text is available yet for this article.
May 2017: Journal of Clinical Immunology
https://www.readbyqxmd.com/read/28429104/paecilomyces-formosus-infection-in-an-adult-patient-with-undiagnosed-chronic-granulomatous-disease
#20
LETTER
Jalal Heshmatnia, Majid Marjani, Seyed Alireza Mahdaviani, Parvaneh Adimi, Mihan Pourabdollah, Payam Tabarsi, Fereshte Mahdavi, Hamidreza Jamaati, Ian M Adcock, Johan Garssen, Aliakbar Velayati, Davood Mansouri, Esmaeil Mortaz
No abstract text is available yet for this article.
May 2017: Journal of Clinical Immunology
journal
journal
28117
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"