Dengyue Yuan, Chaowei Zhou, Tao Wang, Fangjun Lin, Hu Chen, Hongwei Wu, Rongbin Wei, Zhiming Xin, Ju Liu, Yundi Gao, Defang Chen, Shiyong Yang, Yan Wang, Yundan Pu, Zhiqiong Li
Peptide YY (PYY) is a potent anorectic neuropeptide implicated in feeding regulation in mammals. However, the involvement of PYY in the feeding behavior of teleosts has not been well understood. In this study, we employed molecular, real-time quantitative PCR and physiological studies to characterize the structure, distribution, and appetite regulatory effects of PYY in Schizothorax prenanti (S. prenanti). A very high conservation in PYY sequences was found in teleosts. PYY is widely expressed, with the highest levels of expression in telencephalon, medulla oblongata, pituitary and hypothalamus of S...
May 2014: Regulatory Peptides