journal
MENU ▼
Read by QxMD icon Read
search

Clinics in Laboratory Medicine

journal
https://www.readbyqxmd.com/read/29412893/pathology-central-and-essential
#1
EDITORIAL
Danny A Milner
No abstract text is available yet for this article.
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412888/global-health-and-pathology
#2
Danny A Milner
No abstract text is available yet for this article.
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412887/lymphoma-and-pathology-in-sub-saharan-africa-current-approaches-and-future-directions
#3
REVIEW
Tamiwe Tomoka, Nathan D Montgomery, Eric Powers, Bal Mukunda Dhungel, Elizabeth A Morgan, Maurice Mulenga, Satish Gopal, Yuri Fedoriw
The care of patients with lymphoma relies heavily on accurate tissue diagnosis and classification. In sub-Saharan Africa, where lymphoma burden is increasing because of population growth, aging, and continued epidemic levels of human immunodeficiency virus infection, diagnostic pathology services are limited. This article summarizes lymphoma epidemiology, current diagnostic capacity, and obstacles and opportunities for improving practice in the region.
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412886/pathology-based-research-in-africa
#4
REVIEW
Maria P Lemos, Terrie E Taylor, Suzanne M McGoldrick, Malcolm E Molyneux, Manoj Menon, Steve Kussick, Nonhlanhla N Mkhize, Neil A Martinson, Andrea Stritmatter, Julie Randolph-Habecker
The process of conducting pathology research in Africa can be challenging. But the rewards in terms of knowledge gained, quality of collaborations, and impact on communities affected by infectious disease and cancer are great. This report reviews 3 different research efforts: fatal malaria in Malawi, mucosal immunity to HIV in South Africa, and cancer research in Uganda. What unifies them is the use of pathology-based approaches to answer vital questions, such as physiology, pathogenesis, predictors of clinical course, and diagnostic testing schemes...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412885/from-access-to-collaboration-four-african-pathologists-profile-their-use-of-the-internet-and-social-media
#5
REVIEW
Julia Royall, Micongwe Moses Isyagi, Yawale Iliyasu, Robert Lukande, Edda Vuhahula
The shared practice of pathology via the Internet holds great potential for pathologists in sub-Saharan Africa (SSA) and their global partners. Application of the Internet is constrained by issues of bandwidth, cost, and power. The penetration of mobile telephony and the arrival of smartphones have changed the use of Internet and social media in Africa and therefore the work of the 4 African pathologists featured in this article. As pathology in SSA struggles for visibility and usefulness, the Internet and its electronic applications provide a critical infrastructure as well as a podium for pathologists across the continent...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412884/training-the-next-generation-of-african-pathologists
#6
REVIEW
Ann Marie Nelson, Martin Hale, Mohenou Isidore Jean-Marie Diomande, Quentin Eichbaum, Yawale Iliyasu, Raphael M Kalengayi, Belson Rugwizangoga, Shahin Sayed
Quality patient care requires correct and timely evidence-based diagnoses. Pathology and laboratory medicine training varies significantly across the continent, but is inadequate to serve the needs of the population. This article summarizes the current state of pathology workforce and training in sub-Saharan Africa; discusses challenges to recruitment and retention; and outlines the necessary elements for training and sustaining a robust workforce in pathology and laboratory medicine. The authors provide several case studies of institutions around the continent that include expansion of existing programs, a de novo program, South-South collaborations, and skill building for the existing workforce...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412883/global-health-pathology-research-purpose-and-funding
#7
REVIEW
John S Flanigan, Shannon L Silkensen, Nicholas G Wolf
Like in all areas of science, it is important for funders and investigators of pathology to work together to develop a well-designed, well-executed clinical research agenda. In the first section of this article, the authors discuss how the National Institutes of Health (NIH) peer-review process applies to global health pathology research projects. Then, the authors present an illustrative sampling of NIH-funded projects with performance sites in low- and middle-income countries with 2 examples focused on cancer and anatomic pathology...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412882/biospecimens-and-biobanking-in-global-health
#8
REVIEW
Maimuna Mendy, Rita T Lawlor, Anne Linda van Kappel, Peter H J Riegman, Fay Betsou, Oliver D Cohen, Marianne K Henderson
Biobanks provide a critical infrastructure to support research in human health. Biospecimens and their accompanying data are increasingly needed to support biomedical research and clinical care. The original text was initially published in the Handbook for Cancer Research in Africa. The value of this publication is great as it underlines the importance of biobanks in Africa as a key resource to increase quality scientific research and participate in global health research. Therefore, a revision to extend these principles to other low resource contexts, to include updated material and references and add the topic of biobank sustainability were relevant...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412881/cytopathology-in-low-medical-infrastructure-countries-why-and-how-to-integrate-to-capacitate-health-care
#9
REVIEW
Andrew S Field
Fine-needle aspiration cytology is a rapid, accurate, minimally invasive, inexpensive biopsy technique requiring minimal laboratory infrastructure and proceduralist costs. It provides infectious and noncommunicable disease diagnoses and will play an essential role in the establishment of cancer services in low-income and middle-income countries (LMICs). The use of molecular and other ancillary tests on cytology material is rapidly expanding in high-income countries and will spread to LMICs. Establishing cytology services requires increased training of cytopathologists and cytotechnologists, increased education of clinicians in the use of diagnostic cytopathology, and commitment and funding from governments and specialist training groups...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412880/breast-cancer-in-low-and-middle-income-countries-why-we-need-pathology-capability-to-solve-this-challenge
#10
REVIEW
Yehoda M Martei, Lydia E Pace, Jane E Brock, Lawrence N Shulman
Breast cancer is the leading cause of cancer mortality among women in developing countries. Timely and accurate histopathological diagnosis of breast cancer is critical to delivering high-quality breast cancer care to patients in low- and middle-income countries (LMIC). The most important prognostic factors in breast cancer along with tumor size and nodal status are tumor grade, estrogen receptor status, as well as HER2 status in countries where specific targeted therapies are available. In addition, detailed and complete cancer registry data are needed to assess a country's disease burden and guide disease prioritization and allocation of resources for breast cancer treatment...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412879/world-health-organization-list-of-priority-medical-devices-for-cancer-management-to-promote-universal-coverage
#11
REVIEW
André M Ilbawi, Adriana Velazquez-Berumen
Universal coverage of basic laboratory services is fundamental to achieving sustainable development goals and attaining health for all. Yet, comprehensive laboratory services are unavailable to large percentages of the global population. To help policymakers identify a basic package of services for cancer, the World Health Organization (WHO) published Priority Medical Devices for Cancer Management. The package of services includes key interventions, associated devices and technologies, and the requirements for health workforce and infrastructure...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412878/practical-successes-in-telepathology-experiences-in-africa
#12
REVIEW
Nathan D Montgomery, Tamiwe Tomoka, Robert Krysiak, Eric Powers, Maurice Mulenga, Coxcilly Kampani, Fred Chimzimu, Michael K Owino, Bal Mukunda Dhungel, Satish Gopal, Yuri Fedoriw
Across much of Africa, there is a critical shortage of pathology services necessary for clinical care. Even in settings where specialty-level clinical care, such as medical oncology, is available, access to anatomic pathology services has often lagged behind. Pathology laboratories in the region are challenging to establish and maintain. This article describes the successful implementation of telepathology services in Malawi and reviews other successful programs developed to support diagnostic pathology in resource-limited settings...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412877/strengthening-laboratory-management-toward-accreditation-a-model-program-for-pathology-laboratory-improvement
#13
REVIEW
Linda R Andiric, Lawrence A Chavez, Mira Johnson, Kenneth Landgraf, Danny A Milner
The Strengthening Laboratory Management Toward Accreditation (SLMTA) program and subsequent Stepwise Laboratory Quality Improvement Process Toward Accreditation (SLIPTA) checklist were a response to the need for high-quality laboratories to combat the human immunodeficiency virus (HIV) epidemic and provide patients with the highest-quality care. The two tools work together to create a culture of quality in laboratories and allow the identification of gaps. The ultimate goal for any laboratory is to achieve a standard benchmark for quality and these programs have been highly successful in initially affecting the HIV epidemic but continuously improving laboratory quality across all diseases...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412876/building-cross-country-networks-for-laboratory-capacity-and-improvement
#14
REVIEW
Miriam Schneidman, Martin Matu, John Nkengasong, Willie Githui, Simeon Kalyesubula-Kibuuka, Kelly Araujo Silva
Laboratory networks are vital to well-functioning public health systems and disease control efforts. Cross-country laboratory networks play a critical role in supporting epidemiologic surveillance, accelerating disease outbreak response, and tracking drug resistance. The East Africa Public Health Laboratory Network was established to bolster diagnostic and disease surveillance capacity. The network supports the introduction of regional quality standards; facilitates the rollout and evaluation of new diagnostic tools; and serves as a platform for training, research, and knowledge sharing...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412875/voices-from-the-field-interviews-with-global-health-pathology-volunteers
#15
REVIEW
Timothy K Amukele, Sarah Riley, Merih T Tesfazghi
Volunteerism in pathology is an uncommon experience. This article attempts to shed light on this experience based on guided narrative interviews. The authors' interviews suggest that prototypical pathology volunteers participate in long-term missions, tend to be later in their careers, are motivated by personal reasons, get involved in volunteering through nongovernmental organizations, focuses on capacity building, and at least partially self-funds their efforts.
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412874/building-laboratory-capacity-to-strengthen-health-systems-the-partners-in-health-experience
#16
REVIEW
Juan Daniel Orozco, Lauren A Greenberg, Ishaan K Desai, Fabienne Anglade, Deogratias Ruhangaza, Mira Johnson, Louise C Ivers, Danny A Milner, Paul E Farmer
The diagnostic laboratory is essential to patient care and to the achievement of health equity. Through the development of quality laboratories in settings burdened by poverty and weak health systems, Partners In Health has demonstrated the critical contributions of clinical laboratories to the care of patients with HIV, tuberculosis, and cancer, among other conditions. The lessons learned through the organization's experience include the importance of well-trained and well-supported staff; reliable access to supplies, reagents, and diagnostic equipment; adequate facilities to provide diagnostic services; the integration of laboratories into networks of care; and accompaniment of the public health sector...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29412873/laboratories-as-the-core-for-health-systems-building
#17
REVIEW
Danny A Milner, E Blair Holladay
If it is accepted that health care access to diagnosis and treatment is a universal human right, the principal challenge is how to deliver that health care to all people. Health systems that function are the most effective way to deliver such care; these health systems should cover all of the diseases facing a population. The central role of laboratories in making medical decisions is crucial. If organizations engaged in health systems building tackle a disease category, such a cancer, multiple modalities within and outside of the laboratory have to be improved or installed to make an effective system...
March 2018: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29128079/clinical-flow-cytometry-state-of-the-art-and-new-approaches
#18
EDITORIAL
David M Dorfman
No abstract text is available yet for this article.
December 2017: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29128078/applications-of-mass-cytometry-in-clinical-medicine-the-promise-and-perils-of-clinical-cytof
#19
REVIEW
Gregory K Behbehani
Mass cytometry is a novel technology similar to flow cytometry in which antibodies are tagged with heavy metal molecules rather than fluorophores and then detected with time-of-flight mass spectrometry. This enables measurement of up to 50 simultaneous parameters with no autofluorescent background and little or no spillover or required compensation. Mass cytometry has tremendous potential for the analysis of highly complex clinical samples for the diagnosis and monitoring of malignant and autoimmune disorders...
December 2017: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/29128077/automated-analysis-of-clinical-flow-cytometry-data-a-chronic-lymphocytic-leukemia-illustration
#20
REVIEW
Richard H Scheuermann, Jack Bui, Huan-You Wang, Yu Qian
Flow cytometry is used in cell-based diagnostic evaluation for blood-borne malignancies including leukemia and lymphoma. The current practice for cytometry data analysis relies on manual gating to identify cell subsets in complex mixtures, which is subjective, labor-intensive, and poorly reproducible. This article reviews recent efforts to develop, validate, and disseminate automated computational methods and pipelines for cytometry data analysis that could help overcome the limitations of manual analysis and provide for efficient and data-driven diagnostic applications...
December 2017: Clinics in Laboratory Medicine
journal
journal
28065
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"