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Journal of Tropical Pediatrics

Mecnun Çetin, Nevzat Turfan, Kamuran Karaman, Akkiz Sahin Yasar, Burcu Güven, Perihan Tunçdemir
Objective: To investigate the effect of inflammation on the conducting system of the heart in patients diagnosed with brucellosis. Methods: A total of 42 patients diagnosed with brucellosis and 39 age and sex-matched healthy children were enrolled into the study. Pre- and post-treatment electrocardiographic parameters in brucellosis and control group were recorded from an electrocardiogram for each patient. Results: The results indicated that the parameters including Pmax, Pdis, QTmax, QTdis, QTcdis, Tp-edis interval and Tp-emax/QTmax and Tp-emax/QTcmax ratios, which are known to be key indicators for the prediction of severe atrial or ventricular arrhythmia and sudden cardiac death and also important parameters used as the indicators for the non-invasive evaluation of the transmural heterogeneity were significantly longer in the study group compared with the control group (p < 0...
January 8, 2019: Journal of Tropical Pediatrics
Olga Bengård Hansen, Amabelia Rodrigues, Cesario Martins, Andreas Rieckmann, Christine Stabell Benn, Peter Aaby, Ane Bærent Fisker
Background: In addition to vaccines' specific effects, vaccines may have non-specific effects (NSEs) altering the susceptibility to unrelated infections. Non-live vaccines have been associated with negative NSEs. In 2010, a campaign with the non-live H1N1-influenza vaccine targeted children 6-59 months in Guinea-Bissau. Methods: Bandim Health Project runs a health and demographic surveillance system site in Guinea-Bissau. Using a Cox proportional hazards model, we compared all-cause consultation rates after vs...
December 24, 2018: Journal of Tropical Pediatrics
Tasneem Karim, Alfred Scherzer, Mohammad Muhit, Nadia Badawi, Gulam Khandaker
We aimed to determine the feasibility of using a simplified Developmental Milestone Chart (DMC) for assessment of neurodevelopmental status of children of age ≥1 month and ≤8 years. Participants were assessed by medical practitioners using DMC as part of regular health checkups in three sub-districts in Bangladesh between January and May 2017. Total 256 children were recruited (41.0% girls, mean age 1.3 ± 1.6 years). Total 107 children (41.8%) failed at least one and 3 (1.2%) failed all four developmental milestones...
December 19, 2018: Journal of Tropical Pediatrics
Ehsaneh Taheri, Ramin Heshmat, Mohammad Esmaeil Motlagh, Gelayol Ardalan, Hamid Asayesh, Mostafa Qorbani, Roya Kelishadi
Background: There are limited studies about the association of physical activity (PA) and screen time (ST) with psychiatric distress (PD) among children and adolescents including Iranian populations. Objective: We aimed to examine the independent and combined associations of PA and ST with PD among children and adolescents. Method: This school-based nationwide survey was carried out among 14 880 students (50.8% boys and 75.6% urban inhabitants), of age 6-18 years by cluster and the stratified multistage sampling method from 30 provinces of Iran...
December 15, 2018: Journal of Tropical Pediatrics
Memela Makiwane, Eric Decloedt, Maxwell Chirehwa, Bernd Rosenkranz, Mariana Kruger
Background: The prevalence of adverse drug reaction (ADR) rates in children in sub-Saharan Africa is unknown. Objectives: To describe the prevalence of ADRs in paediatric in-patients at a tertiary hospital in South Africa. Methods: This is a prospective study during a 3-month study period. Data collected included age, sex, diagnosis, medicines received and ADRs experienced. Causality were assessed, using the 10-question Naranjo probability scale and classified according to the Hartwig severity scale...
December 13, 2018: Journal of Tropical Pediatrics
Gopal Agrawal, Sanjay Wazir, Surender Kumar, Bir Singh Yadav, Manish Balde
Objectives: The objective of this study was to show the effects of routine vs. selective fortification of human milk (HM) on short-term growth and metabolic parameters. Methods: Single-centre retrospective pre-post cohort study in India. Preterm infants ≤32 weeks' gestation and weighing ≤1500 g were included. Routine fortification: pre-fixed feed volume (100 ml/kg/day in our unit) at which fortification was done. Selective fortification: feed volume was gradually optimized till 180-200 ml/kg/day...
December 12, 2018: Journal of Tropical Pediatrics
Rong Xiang, Qing Tang, Xiu-Qi Chen, Mu-Yan Li, Mei-Xiong Yang, Xiang Yun, Li Huang, Qing-Wen Shan
Aim: The aim of this study was to evaluate the impact of zinc combined with probiotics (Bifico) on antibiotic-associated diarrhea (AAD) secondary to pneumonia. Methods: A total of 50 patients with AAD secondary to pneumonia were randomly divided into a probiotics group (Bifico) and a combined group (zinc combined with Bifico) and 25 pneumonia patients without AAD as the control group. Serum levels of zinc, diamine oxidase (DAO) activity, D-lactate and intestinal flora [Bifidobacterium, Escherichia coli and Bifidobacterium/E...
December 6, 2018: Journal of Tropical Pediatrics
Theodonata Tuyisenge, Michael B Henry, Peter T Cartledge
No abstract text is available yet for this article.
December 5, 2018: Journal of Tropical Pediatrics
Judy Schoeman, Elena J Ladas, Paul C Rogers, Suvekshya Aryal, Mariana Kruger
Background: Up to 50% of children diagnosed with cancer in low- and middle-income countries are malnourished, which likely affects survival. Subjects and methods: An online survey to paediatric oncology units (POUs) in Africa was done regarding nutritional assessment and care. Results: Sixty-six surveys were received from POUs in 31 countries. Only 44.4% had a dedicated dietician for nutritional assessment and support; 29.6% undertook routine nutritional assessment during treatment...
November 30, 2018: Journal of Tropical Pediatrics
Mariana Kruger, Memela M Makiwane, Sekgele Ramoroka, Sabine L van Elsland, Katherine Lawrence, Bernd Rosenkranz
Aim: The aim of this article was to determine off-label (OL) use in paediatric ambulatory clinics in a South African central hospital. Patients and methods: OL medicine events were documented in three paediatric clinics (general, highly specialized and dedicated HIV paediatric clinics) at Tygerberg Hospital, South Africa, and analysed according to South African medicine registration information. Results: There were 2167 medicine events for 658 children...
November 26, 2018: Journal of Tropical Pediatrics
Yao Xu, Yang Fang Wu, Huang Huang Luo, Dong Dong Zhang, Yue Wu, Peng Hu
Hand, foot and mouth disease (HFMD) is a common infectious disease among children, caused primarily by human enterovirus-A71 (EV-A71) and coxsackievirus-A16 (CV-A16). To date, only two case reports mention that renal involvement can be secondary to or coexisting with CV-A16-associated HFMD. In the present report, we describe a 10-year-old girl who was infected with EV-A71 and subsequently developed a definite acute kidney injury (AKI), mainly based on the characteristic rash, virus isolation, eyelid edema, hypertension, decreased urine output, mild proteinuria and impaired renal function...
November 19, 2018: Journal of Tropical Pediatrics
Quique Bassat
No abstract text is available yet for this article.
December 1, 2018: Journal of Tropical Pediatrics
Amy L Slogrove, Leigh F Johnson, Kathleen M Powis
We aimed to quantify the contribution of excess mortality in HIV-exposed uninfected (HEU) infants to total mortality in HIV-uninfected infants in Botswana and South Africa in 2013. Population attributable fractions (PAFs) and excess infant deaths associated with HIV exposure in HIV-uninfected infants were estimated. Additionally, the Thembisa South African demographic model estimated the proportion of all infant mortality associated with excess mortality in HEU infants from 1990 to 2013. The PAF (lower bound; upper bound) of mortality associated with HIV exposure in HIV-uninfected infants was 16...
October 12, 2018: Journal of Tropical Pediatrics
Quique Bassat, Anuradha Bose, Peter Cartledge, Elizabeth Montgomery Collins, Sophie Jullien, Miguel Lanaspa, Doug Simkiss, Indi Trehan
No abstract text is available yet for this article.
October 1, 2018: Journal of Tropical Pediatrics
Elizabeth Montgomery Collins, Quique Bassat
No abstract text is available yet for this article.
October 1, 2018: Journal of Tropical Pediatrics
Helen M Nabwera, Robin M Bernstein, Schadrac C Agbla, Sophie E Moore, Momodou K Darboe, Mariama Colley, Amadou T Jallow, Richard Bradbury, Jennifer Karafin, Anthony J Fulford, Andrew M Prentice
Background: Malnourished children show variable growth responses to nutritional rehabilitation. We aimed to investigate whether these differences could be explained by variations in growth and energy-regulating hormones. Methods: Quasi-experimental study: Children aged 6-24 months in rural Gambia were recruited to controls if weight-for-height z-score (WHZ) > -2 (n = 22), moderate acute malnutrition if WHZ < -2 and > -3 (n = 18) or severe acute malnutrition if WHZ < -3 (n = 20)...
October 1, 2018: Journal of Tropical Pediatrics
(no author information available yet)
No abstract text is available yet for this article.
September 28, 2018: Journal of Tropical Pediatrics
Madrid Lola, Varo Rosauro, Bassat Quique
No abstract text is available yet for this article.
September 26, 2018: Journal of Tropical Pediatrics
Marcela Fandiño-Cárdenas, Alvaro J Idrovo, Roman Velandia, Jessica Molina-Franky, Jorge L Alvarado-Socarras
Objective: The objectives of this study were to describe the findings of the auditory screening in children of mothers with ZIKV during pregnancy or suspicious of congenital ZIKV, and to determine whether hearing loss was in the first 2 years in life, regardless of whether microcephaly was also present. Methods: This is a cases report. The information was collected and recorded in a database between January 2016 and April 2018. We perform two auditory tests to 3 and 24 months of life...
September 25, 2018: Journal of Tropical Pediatrics
Georgie Mathew, Venkatesh Arumugam, Suresh Murugesan, Neelaveni Duhli, Indira Agarwal
Mucormycosis is a rare fungal infection often seen in immunocompromised hosts. Isolated renal mucormycosis may however present in immunocompetent children as renal failure and has a uniformly poor prognosis if not detected and treated early into the course of illness. We present a 3-year-old boy with unrelenting pyelonephritis in whom serial urine cultures done were negative. A final diagnosis of isolated renal mucormycosis was made by magnetic resonance imaging and renal biopsy.
September 25, 2018: Journal of Tropical Pediatrics
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