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Journal of Tropical Pediatrics

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https://www.readbyqxmd.com/read/29762771/improving-early-neonatal-development-in-conflict-affected-countries
#1
Karen Edmond, Malalai Naziri, Sayed Masoud Sadat
No abstract text is available yet for this article.
May 11, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29741690/severe-multisystem-involvement-of-chronic-granulomatous-disease-in-a-pediatric-patient
#2
Zuhal Bayramoglu, Ibrahim Adaletli, Emine Caliskan, Manolya Acar, Selda Hancerli Torun, Ayper Somer
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder identified by recurrent pyogenic and fungal infections infections secondary to defective nicotinamide adenine dinucleotide phosphate oxidase enzyme. In the present study, we demonstrated a case with a history of multiple segmental lung resections because of invasive bronchopulmonary aspergillosis, multifocal hepatic and splenic granulomas, bilateral adnexal calcific foci presumed to be related with old granulomatous infection and finally gastric outlet obstruction secondary to the involvement of the stomach wall thickening with granulomatous tissue...
May 7, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29688558/diphtheria-in-children-in-northern-haiti
#3
Marc-Mesadieu Exavier, Michele Paul Hanna, Emanise Muscadin, Robert J Freishstat, Jean-Pierre Brisma, Michael F Canarie
Infection with Corynebacterium diphtheriae persists in Haiti. Twenty-six children with clinically severe respiratory diphtheria presented to a hospital in northern Haiti during a 3-year period beginning in early 2015. The mortality rate was 50%. Partial or absent vaccinations as well as delayed and limited care contributed to mortality. This cohort offer insights into the multiple challenges involved in preventing and caring for children with diphtheria in resource-limited settings.
April 23, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29688486/congenital-multidrug-resistant-tuberculosis-in-a-neonate-a-case-report
#4
Tenzin Lhadon, Sophie Jullien
Multidrug-resistant tuberculosis (MDR-TB) is a well-identified raising public health concern worldwide. However, the data available on MDR-TB in children and particularly in the neonate age group are limited. Congenital tuberculosis (TB) is rare, and its diagnosis is challenging because of non-specific manifestations. The choice of anti-tubercular drugs is difficult because of the lack of international consensus as a consequence of the scarcity of evidence-based data on this age group. We hereby present a case from Bhutan of a 23-day-old male neonate with congenital MDR-TB...
April 20, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29684189/correlation-between-perfusion-index-and-crib-score-in-sick-neonates-admitted-to-a-tertiary-center
#5
Jisha Mathew, Chandrakala Bada Shekarappa, Suman Padubidri Nanyam Rao
Objective: The study was to determine the correlation of Perfusion Index (PI) and Clinical Risk Index for Babies (CRIB) score, in assessing the severity of illness in sick neonates. Methods: This was a cross-sectional study conducted at a tertiary care Neonatal Intensive Care Unit (NICU). All eligible neonates, both term and preterm, admitted to the high-dependency unit of the NICU were included, after parental consent. Relevant details of history and examination were collected with a structured proforma...
April 18, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29669137/validation-of-pediatric-weight-estimation-formulae-in-a-suburban-cameroonian-population-a-cross-sectional-study
#6
Clarence Mvalo Mbanga, Valirie Ndip Agbor, Chobufo Ditah, Louise Daniele Toukam, Tsi Njim
We assessed the accuracy of the Nelson, Best Guess and Advanced Pediatric Life Support (APLS) formulae in estimating weight in a suburban Cameroonian pediatric population, by conducting a cross-sectional study using 544 children aged 1 month to 12 years. Agreement between measured and estimated weight was poor for Nelson [concordance correlation coefficient (CCC) 0.89 (95% confidence interval (CI) 0.87-0.90)] and Best Guess [CCC 0.88 (95% CI 0.86-0.90)] formulae, and moderate for the APLS formula [CCC 0.92 (95% CI 0...
April 12, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29669036/acute-motor-axonal-polyneuropathy-following-mumps-infection-in-a-9-year-old-girl
#7
Karunakar Pediredla, Anitha Abimannane, Venkatesh Chandrasekaran, Barath Jagadisan, Niranjan Biswal
A 9-year-old girl presented with lower motor neuron type of paralysis involving limbs, trunk and multiple cranial nerves (7, 9 and 10) with preceding history of mumps 1 week before the onset of weakness. There were no features to suggest either a meningitis or encephalitis in the child. Cerebrospinal fluid showed hypoglycorrhachia and mild protein elevation; magnetic resonance imaging of the brain was normal. Nerve conduction study showed motor axonal neuropathy. Serology for mumps IgM was positive, consistent with a diagnosis of post-mumps acute motor axonal polyneuropathy...
April 12, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29660106/safety-effectiveness-and-feasibility-of-outpatient-management-of-children-with-pneumonia-with-chest-indrawing-at-port-moresby-general-hospital-papua-new-guinea
#8
Rose Morre, Kone Sobi, Wendy Pameh, Paulus Ripa, John D Vince, Trevor Duke
Implementing the World Health Organization (WHO) recommendations on home-based management of pneumonia with chest indrawing is challenging in many settings. In Papua New Guinea, 120 children presenting with the WHO definition of pneumonia were screened for danger signs, comorbidities and hypoxaemia using pulse oximetry; 117 were appropriate for home care. We taught mothers about danger signs and when to return, using structured teaching materials and a video. The children were given a single dose of intramuscular benzylpenicillin, then sent home on oral amoxicillin for 5 days, with follow-up at Days 2 and 6...
April 6, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29660100/assessment-of-iodine-nutritional-status-of-school-age-children-in-kolkata-district-of-west-bengal-state-in-post-iodation-scenario
#9
Udayan Bhattacharya, Amar K Chandra
To evaluate the state of iodine nutrition in post-iodation scenario, 3500 children were examined clinically for endemic goitre. Iodine and thiocyanate were measured in 240 urine samples; iodine content in 210 salt samples was measured. Total goitre prevalence was 6.1%. Median urinary iodine level was 21.80 µg/dl, and mean (±SD) urinary thiocyanate was 0.89 ± 0.49 mg/dl. Iodine content of only 11.9% salt samples was below recommended level of 15 ppm, 25.2% was between 15 and 30 ppm and 62.9% was >30 ppm...
April 6, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29590467/a-retrospective-study-of-neonatal-outcome-in-preeclampsia-at-the-university-hospital-of-the-west-indies-a-resource-limited-setting
#10
Kerri-Ann McKenzie, Helen Trotman
Aim: This study aimed to determine the outcome of neonates born to women with preeclampsia at the University Hospital of the West Indies (UHWI). Methods: This was a retrospective descriptive study looking at the outcome of all babies born to women with preeclampsia and control babies born to normotensive women at the UHWI over a 20-month period. Maternal and neonatal demographic data and course of admission for admitted neonates were recorded. Descriptive analyses were performed...
March 24, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29584924/an-open-label-randomized-controlled-trial-to-compare-weight-gain-of-very-low-birth-weight-babies-with-or-without-addition-of-coconut-oil-to-breast-milk
#11
Sumitha Arun, Manish Kumar, Thomas Paul, Nihal Thomas, Sarah Mathai, Grace Rebekah, Niranjan Thomas
Background: Nutritional guidelines involving the feeding of very low birth weight babies (VLBW) recommend addition of Human Milk Fortifiers to breast milk. Owing to financial constraints, it is a practice in low- and middle-income countries (LMIC) to add coconut oil to aid better weight gain. There are inadequate data on improvement of growth parameters with oral coconut oil supplementation of breast milk. Methods: In this randomized controlled trial, we measured growth parameters and body composition of 60 babies who received either breast milk with coconut oil or breast milk alone...
March 23, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29534241/clinical-features-and-outcome-of-children-with-severe-lower-respiratory-tract-infection-admitted-to-a-pediatric-intensive-care-unit-in-south-africa
#12
Hayley K Hutton, Heather J Zar, Andrew C Argent
Aim: Severe acute lower respiratory tract infection (ALRTI) remains an important cause of childhood morbidity and mortality. Methods: This is a 12-month retrospective cohort study of children (0-12 years) admitted to a pediatric intensive care unit (PICU) with ALRTI to investigate risk factors, clinical course and in-hospital survival. Results: In total, 265 patients (median age = 4 months [2-12 months]) were identified. In all,102 (38...
March 9, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29514329/validation-of-the-subjective-global-nutrition-assessment-sgna-and-screening-tool-for-the-assessment-of-malnutrition-in-paediatrics-stamp-to-identify-malnutrition-in-hospitalized-malaysian-children
#13
Shu Hwa Ong, Winnie Siew Swee Chee, L Mageswary Lapchmanan, Shan Ni Ong, Zhi Chin Lua, Jowynna Xia-Ni Yeo
Background: Early detection of malnutrition in hospitalized children helps reduce length of hospital stay and morbidity. A validated nutrition tool is essential to correctly identify children at risk of malnutrition or who are already malnourished. This study compared the use of the Subjective Global Nutrition Assessment (SGNA, nutrition assessment tool) and Screening Tool for the Assessment of Malnutrition in Paediatrics (STAMP, nutrition screening tool) with objective nutritional parameters to identify malnutrition in hospitalized children...
March 5, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29506083/addition-of-questions-on-parental-factors-to-the-who-integrated-management-of-childhood-illnesses-imci-hiv-algorithm-improves-the-utility-of-the-algorithm-for-diagnosis-of-hiv-infection-in-children
#14
Jagdish Chandra, Puneet Kaur Sahi, Sourabh Gupta, Rohini Ajay Gupta, Renu Dutta, B L Sherwal, Anju Seth, Praveen Kumar, Varinder Singh
The WHO Integrated Management of Childhood Illnesses-HIV (IMCI-HIV) algorithm and its regional adaptation have shown variable performance in clinically identifying HIV-infected children with lack of validation in low prevalence areas. Addition of certain 'parental factors' (proxy indicators of parental HIV) may improve its utility. In this study, children aged 2 months to 5 years were enrolled into Group A (n = 1000, 'suspected symptomatic HIV infected' children as per the IMNCI-HIV algorithm) and group B (n = 50, children newly diagnosed with HIV infection)...
February 28, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29617940/intraosseous-versus-intravenous-access-in-pediatric-septic-shock-patients-admitted-to-alexandria-university-pediatric-intensive-care-unit
#15
Ahmed A El-Nawawy, Omneya M Omar, Mona Khalil
The cornerstone of emergency management of sepsis is early, goal-directed therapy. The purpose of this study was to evaluate the effect of intraosseous (IO) vs. intravenous (IV) access for resuscitation of patients with septic shock admitted to pediatric intensive care unit. This prospective interventional randomized clinical trial study was conducted on 60 patients with septic shock who need rapid administration of fluids and drugs; 30 cases were randomly chosen for IO vascular access, while the other 30 were selected for IV access...
April 1, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28582585/early-onset-of-htlv-1-associated-myelopathy-tropical-spastic-paraparesis-ham-tsp-and-adult-t-cell-leukemia-lymphoma-atl-systematic-search-and-review
#16
Pedro D Oliveira, Amanda C Kachimarek, Achiléa L Bittencourt
Human T-cell lymphotropic virus type 1 (HTLV-1) is endemic in some regions and its vertical transmission occurs mainly through breastfeeding. About 10% of carriers develop associated diseases including HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), adult T-cell leukemia/lymphoma (ATL) and infectious dermatitis associated with HTLV-1 (IDH). We searched for available case reports of early-onset HAM/TSP and ATL to evaluate demographic and disease aspects in infantile-juvenile patients. In the reviewed literature, 27 HAM/TSP and 31 ATL cases were found...
April 1, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28582577/postnatal-weight-gain-patterns-in-preterm-very-low-birth-weight-infants-born-in-a-tertiary-care-center-in-south-india
#17
Georgie Mathew, Vijay Gupta, Sridhar Santhanam, Grace Rebekah
Background: Extrauterine growth retardation is a common problem in preterm, very-low-birth-weight (VLBW) babies, as well as paucity of growth charts that follow their postnatal growth. Aim: To evaluate and plot postnatal weight gain patterns of preterm VLBW babies of <34 weeks' gestation born at a tertiary care neonatal unit in South India. Methods: Weight gain patterns of all preterm (27 to < 34 weeks' gestation) and VLBW (<1500 g) neonates were used for plotting the centile curves by retrospective review of electronic medical records...
April 1, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28575484/comprehensive-analysis-of-liberal-and-restrictive-transfusion-strategies-in-pediatric-intensive-care-unit
#18
Basak Akyildiz, Nazan Ulgen Tekerek, Ozge Pamukcu, Adem Dursun, Musa Karakukcu, Nazmi Narin, Mehmet Yay, Ferhan Elmali
Background: We prospectively compared restrictive and liberal transfusion strategies for critically ill children regarding hemodynamic and laboratory parameters. Methods: A total of 180 children requiring packed red blood cells (PRBCs) were randomized into two groups: the liberal transfusion strategy group (transfusion trigger < 10 g/dL, Group 1) and the restrictive transfusion strategy group (transfusion trigger ≤ 7 g/dL, Group 2). Basal variables including venous/arterial hemoglobin, hematocrit and lactate levels; stroke volume; and cardiac output were recorded at the beginning and end of the transfusion...
April 1, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28575379/efficacy-of-oral-zinc-supplementation-in-radiologically-confirmed-pneumonia-secondary-analysis-of-a-randomized-controlled-trial
#19
Narendra Kumar Bagri, Neha Bagri, Manisha Jana, Arun Kumar Gupta, Nitya Wadhwa, Rakesh Lodha, Sushil Kumar Kabra, Aruna Chandran, Satinder Aneja, Mona K Chaturvedi, Jitender Sodhi, Sean Patrick Fitzwater, Jagdish Chandra, Bimbadhar Rath, Udaypal S Kainth, Savita Saini, Robert E Black, Mathuram Santosham, Shinjini Bhatnagar
Objective: To evaluate the effect of zinc as an adjuvant therapy in radiologically confirmed pneumonia in children 2-24 months of age. Patients and Methods: We analyzed data of 212 children with pneumonia for whom chest X-ray films were available at enrollment and at least two radiologists agreed on the diagnosis of pneumonia. We compared the time to recovery in the two groups (n = 121, zinc group and n = 91, placebo group) using a Cox proportional hazards regression model...
April 1, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28549190/newborn-care-practices-and-health-seeking-behavior-in-rural-eastern-ethiopia-a-community-based-study
#20
Betemariam Gebre, Sibhatu Biadgilign, Zinaw Taddese, Kebede Deribe, Tsigereda Legesse, Meftuh Omar
Background: Most of the newborn deaths in developing countries occur at home. Up to two-thirds of these deaths would have been prevented if mothers and newborns had received known and effective interventions. The objective of this study is to determine newborn-care practices and health-seeking behavior in rural Eastern Ethiopia. Methods: A community-based cross-sectional study was conducted in Adadle district, Ethiopian Somali Regional State. A multi-stage random sampling technique was applied...
April 1, 2018: Journal of Tropical Pediatrics
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