Dávid Vörös, Orsolya Kiss, Márton Taigiszer, Bettina Réka László, Tamás Ollman, László Péczely, Olga Zagorácz, Erika Kertes, Veronika Kállai, Beáta Berta, Anita Kovács, Zoltán Karádi, László Lénárd, Kristóf László
The goal of the present study is to investigate the role of intraamygdaloid oxytocin in learning-related mechanisms. Oxytocin is a neuropeptide which is involved in social bonding, trust, emotional responses and various social behaviors. By conducting passive avoidance and Morris water maze tests on male Wistar rats, the role of intraamygdaloid oxytocin in memory performance and learning was investigated. Oxytocin doses of 10ng and 100ng were injected into the central nucleus of the amygdala. Our results showed that 10ng oxytocin significantly reduced the time required to locate the platform during the Morris water maze test while significantly increasing the latency time in the passive avoidance test...
February 8, 2024: Peptides