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Neuro Endocrinology Letters

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https://www.readbyqxmd.com/read/29604620/supplementation-of-caricol%C3%A2-gastro-reduces-chronic-gastritis-disease-associated-pain
#1
Friedrich-Anton Weiser, Michael Fangl, Wilhelm Mosgoeller
OBJECTIVE: Papaya and oats are natural food and used in traditional medicine in many parts of the world. Papaya has a high content of enzymes supporting digestive function. Oats are a source of minerals, beta-glucan fibres, immunmodulatory and antiinflammatory probiotic substances. Caricol®-Gastro combines both constituents, it was designed as vegan organic preparation for intestinal inflammatory diseases. We performed a randomized, double blind placebo controlled clinical trial to investigate the potential of Caricol®-Gastro as add on therapy in patients with diagnosed chronic gastritis...
March 1, 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29604619/positive-and-negative-symptoms-in-schizophrenia-and-their-relation-to-depression-anxiety-hope-self-stigma-and-personality-traits-a-cross-sectional-study
#2
Kristyna Vrbova, Jan Prasko, Michaela Holubova, Milos Slepecky, Marie Ociskova
OBJECTIVE: The purpose of the investigation was to explore the relationship between positive or negative symptoms, social anxiety, hope, personality, and self-stigma in patients with schizophrenia spectrum disorders. METHOD: 57 outpatients took part in this cross-sectional study. The structured interview M.I.N.I. International Neuropsychiatric Interview was used to confirm the diagnosis. All patients completed the Liebowitz Social Anxiety Scale, Internalized Stigma of Mental Illness Scale, Beck Depression Inventory-II, Beck Anxiety Inventory, Adult Dispositional Hope Scale, and Temperament and Character Inventory - Revised...
March 1, 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29604618/an-open-prospective-pilot-study-of-a-herbal-combination-relief-as-a-supportive-dietetic-measure-during-alcohol-withdrawal
#3
Kenza Mansoor, Fadi Qadan, Andreas Hinum, Caroline Schneider, Klaus Hechenbichler, Mathias Schmidt, Georg Linsinger, Khalid Matalka
OBJECTIVE: A herbal combination (saffron extract, passion flower herb extract, cocoa seed extract, radish extract and black cumin extract) called "Relief" was designed as a supportive therapy of alcohol withdrawal syndrome (AWS). This combination was based on the scientific evidence of each constituent effect on AWS-like symptoms. In addition, our preclinical studies have shown the effectiveness of Relief on AWS detoxification. The rationale of the study was to document whether the oral intake of the designed content of Relief could have a positive effect on the course of alcohol detoxification by reducing some of the AWS in hospitalized patients...
March 1, 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504737/anxiety-disorders-and-marital-satisfaction
#4
Petra Kasalova, Jan Prasko, Michaela Holubova, Kristyna Vrbova, Daniela Zmeskalova, Milos Slepecky, Ales Grambal
OBJECTIVES: Anxiety disorders can be a burden for the patient and his family. They affect the family everyday functioning, require greater demands on adaptation and re-evaluation of the existing habits of family members and consequently may result in family dysfunction due to anxiety disorders, especially in marital relationship or partnership. However, the knowledge about the impact of anxiety disorders on one or both partners in marital or partner life is still limited. METHOD: The relevant studies were identified through the Web of Science, PubMed, and Scopus databases, within the period 1990-2017...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504736/anxiolytic-effects-of-venlafaxine-olanzapine-combination-in-treatment-of-anxious-depression
#5
Tomas Kulhan, Veronika Marcincakova Husarova, Igor Ondrejka, Ivan Farsky, Gabriela Nosalova
OBJECTIVE: Both venlafaxine and olanzapine have been previously found to have anxiolytic properties, however no study examined the effect of their combination on anxiety in anxious MDD. The aim of this study was to reveal if and when venlafaxine/olanzapine combination (VOC) can reduce the anxiety and depressive symptoms in patients with severe MDD at the level of patients with moderate-severe depression treated with venlafaxine monotherapy. METHODS: Fifty seven patients were included into the study...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504735/does-autoimmunity-play-a-role-in-the-risk-of-implantation-failures
#6
Hanna Motak-Pochrzest, Andrzej Malinowski
158 non-pregnant women with recurrent implantation failures after IVF/ET procedures were tested for peripheral blood autoimmune profile. The control group consisted of 76 patients after first successful IVF procedure and pregnancy outcome. The objective of this study was to investigate different autoantibodies peripheral blood profile after excluding anatomical, endocrinological, endometrial and genetic disorders and to estimate the risk of implantation failures. The study's including criteria were 1.indications for IVF/ET determined by male factor and unexplained infertility 2...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504734/estimation-of-vitamin-d-status-in-patients-with-secondary-and-primary-hypothyroidism-of-different-etiology
#7
Hanna Lawnicka, Anna Galant-Gdula, Ewelina Motylewska, Jan Komorowski, Jacek Swietoslawski, Henryk Stepien
BACKGROUND: Though vitamin D deficiency is a global problem with wide spectrum of severe public health consequences, inadequate vitamin D status still remains one of the most common and untreated medical conditions. Thyroid diseases, including hypothyroidism, also represent the most frequent endocrinopathies in general population. OBJECTIVES: To determine the vitamin D status in hypothyroid patients and to ascertain the status of thyroid hormone replacement. METHODS: The 25(OH)D concentrations (ECLIA) in 71 hypothyroid patients recruited in the Outpatient Clinic of Endocrinology or Department of Clinical Endocrinology were assessed...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504733/qtc-prolongation-after-adhd-medication
#8
Eva Snircova, Veronika Marcincakova Husarova, Igor Ondrejka, Igor Hrtanek, Ivan Farsky, Gabriela Nosalova
OBJECTIVE: Multicenter studies have shown that cardiovascular risks of ADHD medication are extremely low. However, QTc length has been shown to be increased in smaller samples of patients or case reports after stimulant and atomoxetine medication. Based on recent studies of genetic polymorphisms associated with drug-induced QTc prolongation and polymorphisms linkage to regional populations, we hypothesized that the drug-induced QTc prolongation could be a factor of particular polymorphisms linked to specific regional populations undistinguished in multicenter studies...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504732/effect-of-the-dash-diet-and-salt-kardisal%C3%A2-on-blood-pressure-in-adolescents-with-prehypertension-cooperative-multicentre-interventional-study
#9
Jan Janda, Milos Veleminsky, Terezie Sulakova, Bohuslav Prochazka, Jan Eliasek, Pravoslav Stransky, Richard Rokyta
BACKGROUND: In a cooperative multi-center interventional study of 60 probands with prehypertension and normal BMIs were followed for 3 months. DESIGN: The intervention included the DASH diet for 3 months in 30 probands plus sodium limited intake using the low sodium salt Kardisal® (60% NaCl, 40% KCl) (group A) and the DASH diet for 3 months in 30 probands without Kardisal® (group B). RESULTS: In group A (n=26 probands evaluated) the systolic blood pressure (median) decreased significantly from 138 to 129 mmHg (p<0...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504731/expression-of-matrix-metalloproteinase-enzymes-in-endometrium-of-women-with-abnormal-uterine-bleeding
#10
Barbara Grzechocinska, Filip A Dabrowski, Marcin Chlebus, Agata Gondek, Katarzyna Czarzasta, Lukasz Michalowski, Agnieszka Cudnoch-Jedrzejewska, Miroslaw Wielgos
OBJECTIVES: Abnormal uterine bleeding (AUB) is caused by derangement of physiological processes of tissue growth, shedding and regeneration. It is known that interplay between metalloproteinases (MMP's) and tissue inhibitors of metalloproteinases (TIMP's) may play a crucial role in its occurrence. AIM: To define if expression of proMMP-2, MMP-2 and TIMP-1 in endometrium of women with AUB is dependent on steroid sex hormone concentration and histopathological picture...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504730/a-pituitary-abscess-with-one-year-follow-up-after-conservative-treatment-a-case-report
#11
Ning Yuan, Sanbao Chai, Jianbin Sun, Yufang Liu, Sixu Xin, Linong Ji, Xiaomei Zhang
Pituitary abscess (PA) is a rare intrasellar infectious disease presented in less than one percent of all cases of pituitary disease.We reported a case of a 58-year-old woman with a history of type 2 diabetes (T2DM) exhibited with headaches, nasal discharge, anosmia, diabetes insipidus and hypopituitarism due to PA, she was diagnosed based on clinical presentations, endocrine examination and MRI image features. She was treated with nasal wash and antibiotic therapy without surgical intervention. She has received hormone replacement therapy for one year and her condition has gradually become stabilized...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504729/possible-etiology-and-treatment-of-amyotrophic-lateral-sclerosis
#12
Václav Holecek, Richard Rokyta
Amyotrophic Lateral Sclerosis (ALS) is one of the most dangerous and least understood diseases with a pathophysiology that is still largely unknown. In this article we try to provide a pathophysiological explanation of the etiological, pathogenetic, and clinical aspects of ALS. After a description of the rather complicated classification of the disease, we continue with an evaluation of its clinical presentation. The bibliography reveals several suspect etiological factors including atherosclerosis, inflammation, tumors, cataracts, diabetes mellitus type 2, aging, and degeneration of the nervous system...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29504728/the-role-of-lifestyle-changes-in-the-treatment-of-polycystic-ovary-syndrome
#13
Magdalena Smyka, Barbara Grzechocinska, Miroslaw Wielgos
Polycystic ovary syndrome is one of the most common endocrinopathy of the reproductive age. Heterogenity of its clinical symptoms is related to the presence of a number of phenotypes of this disfunction, hence the necessity for individualized treatment is needed. A change of a lifestyle, well-balanced diet and physical activity are the most effective medical way contributing to the improvement of carbohydrate metabolism parameters and weight reduction which reactivates regular ovulation and facilitates getting pregnant...
February 2018: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369603/circadian-blood-pressure-profiles-and-ambulatory-arterial-stiffness-index-in-children-and-adolescents-with-congenital-adrenal-hyperplasia-due-to-21-hydroxylase-deficiency-in-relation-to-their-genotypes
#14
Dominika Janus, Małgorzata Wójcik, Katarzyna Tyrawa, Magdalena Janeczko, Mirosław Bik-Multanowski, Kamil Fijorek, Dorota Drozdz, Kamila Kwiatek, Jerzy B Starzyk
OBJECTIVE: Lifelong steroid therapy and exposure to adrenal androgen excess in 21-hydroxylase deficient (21-OHD) congenital adrenal hyperplasia (CAH) children and adolescents may modify circadian blood pressure profile and result in vascular complications. The objective of the study was to evaluate vascular abnormalities in 21-OHD children and adolescents in relation to their genotypes. DESIGN: A cross-sectional study conducted at a tertiary referral center. PATIENTS: Seventy patients with 21-OHD CAH (27 boys), aged from 3 to 17...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369602/evaluation-of-the-amoxicillin-concentrations-in-amniotic-fluid-placenta-umbilical-cord-blood-and-maternal-serum-two-hours-after-oral-administration
#15
Julia Zareba-Szczudlik, Ewa Romejko-Wolniewicz, Zbigniew Lewandowski, Hanna Rozanska, Aneta Malinowska-Polubiec, Agnieszka Dobrowolska-Redo, Jan Wilczynski, Krzysztof Czajkowski
OBJECTIVES: Amoxicillin is a broad-spectrum beta-lactam antibiotic. Due to its low toxicity, it is commonly used in obstetrics. The objective of this study was to assess amoxicillin concentrations in amniotic fluid, umbilical blood, placenta and maternal serum two hours following oral administration among pregnant women at term and to assess obstetric and non-obstetric factors that might affect amoxicillin's penetration of these tissues. MATERIALS AND METHODS: A total of 30 full-term pregnant women who qualified for elective Caesarean delivery were included in the study...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369601/study-of-locomotion-rearing-and-grooming-activity-after-single-and-or-concomitant-lesions-of-central-and-peripheral-nervous-system-in-rats
#16
Petr Kozler, Dana Maresova, Jaroslav Pokorny
OBJECTIVE: Locomotion, rearing and grooming represent different forms of behaviour and motor activity in rats. In this study, changes in these activities were analysed in relation to impaired function of the nervous system by single and/or concomitant lesions representing an experimental model of the dual diagnosis. METHODS: 32 rats were divided into 4 groups of 8 rats: intact rats, rats with single lesion of peripheral nervous system (PNS) - Marcaine neuropathy, rats with single CNS lesion - cellular brain edema induced by water intoxication, and the concomitant lesions (combination of CNS and PNS lesion in one rat)...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369600/postoperative-hypoparathyroidism-in-patients-after-total-thyroidectomy-retrospective-analysis
#17
Magdalena Marcinkowska, Beata Sniecikowska, Arkadiusz Zygmunt, Jan Brzezinski, Marek Dedecjus, Andrzej Lewinski
OBJECTIVES: Hypoparathyroidism is the most frequent complication of thyroidectomy. The incidence rates of temporary and permanent postoperative hypoparathyroidism vary from 7 to more than 60% and from 0 to 9%, respectively. DESIGN: The aim of the study has been to evaluate the incidence of hypoparathyroidism and clinical manifestations of hypocalcaemia after total thyroidectomy, as well as assess factors that affect the frequency of the symptomatic hypocalcaemia, and benefits resulting from the measurement of parathyroid hormone (PTH) concentration on the first day after thyroidectomy...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369599/application-of-physiotherapy-in-persons-at-risk-of-metabolic-syndrome-development
#18
Marek Zeman, Lenka Valaskova
Problems the locomotor activity and nutritional provisions in the treatment of obesity or metabolic syndrome are currently widely discussed. Based on prevailing experience, the attention in the field of locomotor and fitness activities is rather general, i.e. is mainly focused on the development of the general body fitness and reduction fitness programmes. However, no long-term effects of the locomotor therapy can be expected without appropriate and particularly targeted physiotherapy with a thorough kinesiological examination...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369598/a-case-of-hereditary-thrombophilia-in-a-chinese-han-patient-with-both-antithrombin-deficiency-and-factor-v-leiden-a-case-report-and-literature-review
#19
Xinyuan Li, Weihong Lin, Lijun Zhu, Yonghong Wang, Shan Liu, Jing Liu, Heqian Du, Shaokuan Fang
Hereditary thrombophilia is a blood coagulation disorder that increases the risk of venous thromboembolism, due to several genetic risk factors. Factor V Leiden(FVL) is the most common contributing factor to thrombophilia in the Caucasian population but very rare in Asian population and concurrent occurrence of antithrombin(AT) deficiency and FVL in Chinese Han population is even more rare. We report the case of a 22-year-old female who experienced recurrent intracranial venous thromboses, furthermore, color Doppler ultrasound showed multiple extracranial thromboses...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369597/how-long-does-the-pharmacokinetic-interaction-between-carbamazepine-and-quetiapine-last-after-carbamazepine-withdrawal
#20
Miloslav Kopecek, Petr Potmesil
OBJECTIVES: Carbamazepine and quetiapine are drugs that are used as mood stabilizers in the treatment of bipolar disorders. A series of studies has shown that concurrent use of carbamazepine decreases quetiapine serum level due to induction of CYP3A enzymes by carbamazepine. METHODS: In a 30-year-old bipolar patient with mania treated with quetiapine 1200 mg and carbamazepine 900 mg per day, we measured quetiapine serum level before and after carbamazepine withdrawal...
December 2017: Neuro Endocrinology Letters
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