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Neuro Endocrinology Letters

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https://www.readbyqxmd.com/read/29369603/circadian-blood-pressure-profiles-and-ambulatory-arterial-stiffness-index-in-children-and-adolescents-with-congenital-adrenal-hyperplasia-due-to-21-hydroxylase-deficiency-in-relation-to-their-genotypes
#1
(no author information available yet)
OBJECTIVE: Lifelong steroid therapy and exposure to adrenal androgen excess in 21-hydroxylase deficient (21-OHD) congenital adrenal hyperplasia (CAH) children and adolescents may modify circadian blood pressure profile and result in vascular complications. The objective of the study was to evaluate vascular abnormalities in 21-OHD children and adolescents in relation to their genotypes. DESIGN: A cross-sectional study conducted at a tertiary referral center. PATIENTS: Seventy patients with 21-OHD CAH (27 boys), aged from 3 to 17...
December 25, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369602/evaluation-of-the-amoxicillin-concentrations-in-amniotic-fluid-placenta-umbilical-cord-blood-and-maternal-serum-two-hours-after-oral-administration
#2
(no author information available yet)
OBJECTIVES: Amoxicillin is a broad-spectrum beta-lactam antibiotic. Due to its low toxicity, it is commonly used in obstetrics. The objective of this study was to assess amoxicillin concentrations in amniotic fluid, umbilical blood, placenta and maternal serum two hours following oral administration among pregnant women at term and to assess obstetric and non-obstetric factors that might affect amoxicillin's penetration of these tissues. MATERIALS AND METHODS: A total of 30 full-term pregnant women who qualified for elective Caesarean delivery were included in the study...
December 25, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369601/study-of-locomotion-rearing-and-grooming-activity-after-single-and-or-concomitant-lesions-of-central-and-peripheral-nervous-system-in-rats
#3
(no author information available yet)
OBJECTIVE: Locomotion, rearing and grooming represent different forms of behaviour and motor activity in rats. In this study, changes in these activities were analysed in relation to impaired function of the nervous system by single and/or concomitant lesions representing an experimental model of the dual diagnosis. METHODS: 32 rats were divided into 4 groups of 8 rats: intact rats, rats with single lesion of peripheral nervous system (PNS) - Marcaine neuropathy, rats with single CNS lesion - cellular brain edema induced by water intoxication, and the concomitant lesions (combination of CNS and PNS lesion in one rat)...
December 25, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369599/application-of-physiotherapy-in-persons-at-risk-of-metabolic-syndrome-development
#4
(no author information available yet)
Problems the locomotor activity and nutritional provisions in the treatment of obesity or metabolic syndrome are currently widely discussed. Based on prevailing experience, the attention in the field of locomotor and fitness activities is rather general, i.e. is mainly focused on the development of the general body fitness and reduction fitness programmes. However, no long-term effects of the locomotor therapy can be expected without appropriate and particularly targeted physiotherapy with a thorough kinesiological examination...
December 25, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369598/a-case-of-hereditary-thrombophilia-in-a-chinese-han-patient-with-both-antithrombin-deficiency-and-factor-v-leiden-a-case-report-and-literature-review
#5
(no author information available yet)
Hereditary thrombophilia is a blood coagulation disorder that increases the risk of venous thromboembolism, due to several genetic risk factors. Factor V Leiden(FVL) is the most common contributing factor to thrombophilia in the Caucasian population but very rare in Asian population and concurrent occurrence of antithrombin(AT) deficiency and FVL in Chinese Han population is even more rare. We report the case of a 22-year-old female who experienced recurrent intracranial venous thromboses, furthermore, color Doppler ultrasound showed multiple extracranial thromboses...
December 25, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369597/how-long-does-the-pharmacokinetic-interaction-between-carbamazepine-and-quetiapine-last-after-carbamazepine-withdrawal
#6
(no author information available yet)
OBJECTIVES: Carbamazepine and quetiapine are drugs that are used as mood stabilizers in the treatment of bipolar disorders. A series of studies has shown that concurrent use of carbamazepine decreases quetiapine serum level due to induction of CYP3A enzymes by carbamazepine. METHODS: In a 30-year-old bipolar patient with mania treated with quetiapine 1200 mg and carbamazepine 900 mg per day, we measured quetiapine serum level before and after carbamazepine withdrawal...
December 25, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369596/melatonin-with-adenosine-solubilized-in-water-and-stabilized-with-glycine-for-oncological-treatment-technical-preparation-effectivity-and-clinical-findings
#7
(no author information available yet)
Melatonin has shown the potential to inhibit growth of different tumors, both in vitro and in vivo. There is clear evidence that the administration of melatonin alone or in combination with chemo and radiotherapy in cancer patients with advanced solid tumors has been associated with improved outcomes of tumor regression and survival. Moreover, chemotherapy has been shown to be better tolerated in patients treated with melatonin. However, there are different ways of preparation and administration of melatonin to the patient...
December 25, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369595/insight-in-schizophrenia-a-double-edged-sword
#8
(no author information available yet)
Lack of insight is defined as a loss of ability to distinguish that one's unusual and unreal experiences should be the symptoms of the psychiatric disorder requiring treatment. Lack of insight may be considered as a core symptom of schizophrenia. The concept of insight has been regarded for a long time as necessary for treatment, which improves adherence and makes a better prognosis. Increased insight in schizophrenia has been associated not only with benefits, but also bring trouble in the form of self-stigma, low self-esteem, reduced patient's hope, diminished quality of life, and increased suicidality...
December 25, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298287/polysomnography-based-diagnosis-in-mexican-adult-patients-with-obstructive-sleep-apnea-syndrome-osas-clinical-suspicion
#9
Edgar Arrazola-Cortés, Josefina Hernández-Cervantes, Brenda González-Pérez, Sergio Sauri-Suárez, Luz Berenice López-Hernández, Christian Gabriel Toledo-Lozano, Vanessa Orellana-Villazón, Sofía Lizeth Alcaraz-Estrada, Silvia García
INTRODUCTION: Obstructive sleep apnea syndrome (OSA) occurs in 2-4% of adults, increasing by 2.5 times the risk of sudden death. OBJECTIVE: Establish the concordance of the clinical diagnostic and electrical diagnosis in an adult series that underwent polysomnography. MATERIALS AND METHODS: Patients with sleep disorders that underwent consecutively polysomnography recording. RESULTS: In this study, 51 subjects from 24 to 77 years old (54...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298285/the-relationship-between-breast-cancer-treatment-tumour-type-and-vitamin-d-level-in-pre-and-postmenopausal-women
#10
Joanna Streb, Izabela Glanowska, Anna Streb, Joanna Szpor, Koleta Kryka, Paweł Potocki, Małgorzata Wójcik, Robert Jach
OBJECTIVE: Vitamin D deficiency has been linked to a higher risk of cancer. There is insufficient data regarding the influence of treatment on vitamin D status. The aim of this study was to compare pre- and post-treatment levels of 25(OH)D in premenopausal and postmenopausal women with breast cancer with a different receptor status (ER-estrogen receptors, PR-progesterone receptors) and in healthy controls. METHODS: 49 patients with breast cancer (23 premenopausal), and 28 healthy controls matched for age, menopausal status and BMI...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298284/adherence-self-stigma-and-discontinuation-of-pharmacotherapy-in-patients-with-anxiety-disorders-cross-sectional-study
#11
Andrea Cinculova, Jan Prasko, Dana Kamaradova, Marie Ociskova, Klara Latalova, Kristyna Vrbova, Radim Kubinek, Barbora Mainerova, Ales Grambal, Anezka Tichackova
INTRODUCTION: Treatment adherence is one of the main factors affecting the success of treatment and, secondarily, the quality of life and social adaptation of the patients. The aim of this study was to investigate the association between self-stigmatization, treatment adherence and history of discontinuation of drug treatment. METHODS: The cross-sectional study was conducted on 120 (98 completed all the questionnaires) neurotic outpatients treated in the University Hospital Olomouc...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298283/kisspeptin-permits-the-sexual-development-of-female-rats-with-normal-and-precocious-puberty-but-is-not-a-trigger-for-it
#12
Wei Song, Kailin Li, Chao Sun, Jiang Xue
OBJECTIVE: We inferred how KISS-1/GPR54 system to involved in precocious puberty by observing hormones level during the process of precocious puberty in model and normal rats during sexual development and the estrus cycle. METHOD: Female rats were divided randomly into CPP and control groups; the former were injected with NMDA twice daily, and control groups were injected with saline. Blood and tissue samples were collected and measured during the stages of prepuberty, vaginal opening, estrus, proestrus and diestrus...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298282/the-effects-of-growth-hormone-therapy-on-the-somatic-development-of-a-group-of-polish-children-with-silver-russell-syndrome
#13
Magdalena Sienko, Elżbieta Petriczko, Stanislaw Zajaczek, Agata Zygmunt-Gorska, Jerzy Starzyk, Alicja Korpysz, Jan Petriczko, Alicja Walczak, Mieczysław Walczak
OBJECTIVE: Silver-Russell Syndrome is both clinically and genetically a heterogeneous syndrome. Among the most important dysmorphic features of this condition are: a triangular shaped face with a small mandible, a prominent frontal eminence, a thin vermilion border with downward-pointing lip corners, clino- and brachydactyly of the 5th fingers as well as body asymmetry. The most well-known genetic mutations in this syndrome are: the 11p15 epimutation (20-60% patients) and the maternal uniparental chromosome 7 disomy present in 7% to 15% of patients...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298281/an-experimental-model-of-the-dual-diagnosis-effect-of-cytotoxic-brain-edema-plus-peripheral-neuropathy-on-the-spontaneous-locomotor-activity-of-rats
#14
Petr Kozler, Dana Maresova, Jaroslav Pokorny
OBJECTIVE: The aim of the study was to find how a simultaneous impairment of the CNS (cellular brain edema induced by water intoxication) and PNS (blockade of the right forelimb brachial plexus by local anesthewtic - Marcaine) affects spontaneous locomotor activity of adult rats. METHODS: Rats were divided into groups of animals without water intoxication (without WI) - A,B,C, and those that were water intoxicated (induction of brain edema - after WI) - D,E,F. Both groups were further divided into intact ones (A,D), animals with PNS lesion (Marcaine) (B,E) and sham-operated animals (C,F)...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298280/complete-objective-response-stable-for-5-years-with-the-di-bella-method-of-multiple-metastatic-carcinoma-of-the-breast
#15
Giuseppe Di Bella, Biagio Colori, Rosilde Toscano
Breast cancer is the most common cancer and the leading cause of cancer death among women. Despite all efforts, about 11,939 deaths and 50,000 new diagnoses for breast cancer were estimated among Italian women in 2016. Therefore new approaches are needed to improve the survival and higher remission rates. We present a case of a woman with carcinoma of the breast and multiple metastases after right mastectomy, axillary dissection, repeated cycles of chemo and radiotherapy, and estrogen block. Biological method formulated by Prof...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298278/the-impact-of-air-pollution-to-central-nervous-system-in-children-and-adults
#16
Radim J Sram, Milos Veleminsky, Milos Veleminsky, Jana Stejskalová
The aim of this paper was to review studies analyzing the associations between air pollution and neurodevelopment in children as well as the effect on adult population. Effect of prenatal exposure to polycyclic aromatic hydrocarbons (PAHs, benzo[a]pyrene, B[a]P) were already studied on cohorts from New York, Poland, China, and Spain. All results indicate changes of child behavior and neurodevelopment at the age of 3-9 years, decrease of IQ, increase of Attention Deficit Hyperactivity Disorder (ADHD), decrease of brain-derived neurotrophic factor (BDNF), reduction of left hemisphere white matter...
December 4, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29369600/postoperative-hypoparathyroidism-in-patients-after-total-thyroidectomy-retrospective-analysis
#17
Magdalena Marcinkowska, Beata Sniecikowska, Arkadiusz Zygmunt, Jan Brzezinski, Marek Dedecjus, Andrzej Lewinski
OBJECTIVES: Hypoparathyroidism is the most frequent complication of thyroidectomy. The incidence rates of temporary and permanent postoperative hypoparathyroidism vary from 7 to more than 60% and from 0 to 9%, respectively. DESIGN: The aim of the study has been to evaluate the incidence of hypoparathyroidism and clinical manifestations of hypocalcaemia after total thyroidectomy, as well as assess factors that affect the frequency of the symptomatic hypocalcaemia, and benefits resulting from the measurement of parathyroid hormone (PTH) concentration on the first day after thyroidectomy...
December 3, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298286/new-criteria-for-gestational-diabetes-mellitus-do-they-impact-the-outcome
#18
Julia Zareba-Szczudlik, Dominika Pykalo-Gawinska, Cieszymierz Gawinski, Zbigniew Lewandowski, Aneta Malinowska-Polubiec, Agnieszka Dobrowolska-Redo, Krzysztof Czajkowski, Jan Wilczynski, Ewa Romejko-Wolniewicz
OBJECTIVE: The aim of the study was to compare the perinatal outcome of pregnancies in mothers who were diagnosed with gestational diabetes mellitus (GDM) with previous versus current Polish Gynecological Society (PTG) criteria. METHODS: 475 patients were divided into three groups. In group A, the patients only met the previous PTG criteria for a GDM diagnosis, i.e., those with a blood glucose level of 140-152 mg/dl 2 hours after administration, a fasting glucose level <92 mg/dl, and a blood glucose level <180 mg/dl 1 hour after administration...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29298279/severe-chronic-lithium-intoxication-in-patient-treated-for-bipolar-disorder
#19
Ivana Stetkarova, Vaclav Bocek, Alsu Gismatullina, Zuzana Svobodova, Tomas Peisker
OBJECTIVE: Lithium has been long used in psychiatry as an adjuvant treatment for bipolar disorder. Chronic lithium intoxication is very rare. DESIGN: We present the case of a 72-year-old female, treated with lithium for more than 10 years for bipolar disorder, who was admitted for gait impairment with weakness of limbs, myoclonus, speech impairment and memory disturbances. RESULTS: Diagnosis of lithium intoxication was based on clinical picture and determination of serum lithium levels...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29200254/-lack-of-knowledge-is-no-excuse-hiv-positive-patient-with-progressive-multifocal-leukoencephalopathy-case-report-from-kenya
#20
(no author information available yet)
Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease that affects the central nervous system, which has high morbidity and mortality and no effective, targeted therapies are available. According to the data from developing countries, it affects about 3 to 5% patients who are HIV positive. We present a case of a 27-year-old patient, who got infected with the HIV virus from his mother. The patient had poor compliance to the therapy since its initiation. Due to poor compliance and immunological and virological failure of the first line ARVs, the patient developed PML...
November 4, 2017: Neuro Endocrinology Letters
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