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Neuro Endocrinology Letters

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https://www.readbyqxmd.com/read/28871717/acromegaly-determination-using-discriminant-analysis-of-the-three-dimensional-facial-classification-in-taiwanese
#1
Ming-Hsu Wang, Jen-Der Lin, Chen-Nen Chang, Wen-Ko Chiou
OBJECTIVES: The aim of this study was to assess the size, angles and positional characteristics of facial anthropometry between "acromegalic" patients and control subjects. We also identify possible facial soft tissue measurements for generating discriminant functions toward acromegaly determination in males and females for acromegaly early self-awareness. MATERIAL AND METHODS: This is a cross-sectional study. Subjects participating in this study included 70 patients diagnosed with acromegaly (35 females and 35 males) and 140 gender-matched control individuals...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871716/the-influence-of-eruca-sativa-arugula-on-pharmacokinetics-of-sildenafil-in-rats
#2
Eyad Mallah, Soadad Saleh, Walid Abu Rayyan, Wael Abu Dayyih, Feras Darwish Elhajji, Mohammed Mima, Riad Awad, Tawfiq Arafat
OBJECTIVES: A drug like Sildenafil is commonly used for the treatment of erectile dysfunction. Eruca sativa is known as a garden plant used in folk medicine to enhance the sexual desire in males. Nevertheless, the interaction of Sildenafil and Eruca sativa was not studied. In the current study, we aimed to examine the influence of Eruca sativa on Sildenafil pharmacokinetics in rats. STUDY DESIGN: A crossover experiment with washout period of two weeks was conducted...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871715/personality-as-significant-predictor-of-post-stroke-anxiety
#3
Andrea Solgajová, Tomáš Sollár, Gabriela Vörösová, Dana Zrubcová
OBJECTIVES: Anxiety in stroke patients is very frequent. It negatively influences the whole recovery process. The study objective is to study personality traits, age, gender, and type of stroke as predictors of anxiety in stroke patients. METHODS: Research presents a prospective cross-sectional descriptive study. The sample consisted of 74 hospitalized stroke patients. The data collection methods were the HADS for anxiety measurement and the Mini IPIP for evaluation of five personality factors...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871714/borderline-personality-disorder-and-unmet-needs
#4
Ales Grambal, Jan Prasko, Marie Ociskova, Milos Slepecky, Antonia Kotianova, Zuzana Sedlackova, Marta Zatkova, Petra Kasalova, Dana Kamaradova
BACKGROUND: Borderline personality disorder (BPD) is a disabling psychiatric condition with a chronic and challenging course. BPD is reflected as a disorder of self-regulation" and is associated with both psychological vulnerabilities and social relations that fail to support basic emotional needs. The objective of the paper is to provide the up-to-date data on the unmet needs of BPD patients and their families. METHOD: A computerized search of the literature printed between January 1990 and May 2017 was conducted in PubMed, and additional papers were extracted using keywords "borderline personality disorder,"needs," "pharmacotherapy," "psychotherapy," "CBT," and "family" in various combinations...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871713/cognitive-functions-and-serum-cortisol-concentration-in-perimenopausal-and-postmenopausal-women-working-non-manually
#5
Dorota Raczkiewicz, Beata Sarecka-Hujar, Alfred Owoc, Iwona Bojar
OBJECTIVES: To asses a possible relationship between serum cortisol concentration and cognitive function in peri- and postmenopausal women engaging in non-manual work. METHODS: The Montreal Cognitive Assessment (MoCA) was used to screen women for the study and the Computerized Neurocognitive-assessment Software (CNS) Vital Signs to diagnose cognitive functions. RESULTS: Cognitive functions and serum cortisol concentration did not differ between women in early and late perimenopause and postmenopause...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871712/some-quantitative-eeg-features-in-default-mode-resting-state-network-under-general-anaesthesia
#6
Peter Jombík, Michal Drobny, Beata Saniova, Martin Fischer, Petra Kaderjaková, Marianna Lajčiaková, Erika Bakosova, Eva Drobna, Petr Bob, Vladimír Nosáľ
OBJECTIVES: The default mode resting state network (DMRSN) constitutes a circuit which is active in conditions when the subject is at rest. We tested the hypothesis that its function will be altered during unconsciousness. METHODS: Changes in the mean squared coherences in five conventional frequency bands (delta to gamma) in DMRSN during general anaesthesia (GA) were investigated in 39 patients. They were compared with the normal EEG of 86 alert subjects, severely abnormal EEG of 112 patients with dementia and/or encephalopathy, and the mathematical model of brain death...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871711/analysis-of-the-rs13306560-functional-variant-in-the-promoter-region-of-the-mthfr-gene-in-sporadic-parkinson%C3%A2-s-disease
#7
Silvia García, Luis Javier Cano-Martínez, Ramón Mauricio Coral-Vázquez, Agustín Coronel-Perez, Benjamín Gómez-Díaz, Christian Gabriel Toledo-Lozano, Martha Patricia Gallegos-Arreola, Luis Dávila-Maldonado, Dulce Adeí Jimenez-Hernández, Sofía Lizeth Alcaraz-Estrada, Luz Berenice López-Hernández
OBJECTIVE: Among susceptibility genes for Sporadic Parkinson´s Disease (SPD), the MTHFR gene has been suggested as candidate. The A allele of the functional variant rs13306560 in its promoter region has been liked to decreased transactivation capacity. Therefore, we sought to determine a possible association of the rs13306560 and SPD. METHODS: In total, 237 individuals were genotyped, 113 patients with SPD diagnosed according to the Queen Square Brain Bank criteria and 124 neurologically healthy controls...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871710/importance-of-education-in-the-prevention-of-diabetic-foot-syndrome
#8
Jitka Pokorna
To the Editor, Diabetic foot syndrome (DFS) is defined by the WHO as ulceration or destruction of foot tissue in diabetic patients associated with neuropathy, with different degrees of the disease existing and frequently also with infection. The statistics are frightening: more than million amputations are annually carried out worldwide due to diabetic foot (Foster and Lauver 2014) and these amputations represent as far as 70% of all non-traumatic amputations. In 2013, 861 647 patients were treated for diabetes mellitus in Czech Republic, including 44 657 patients with diabetic foot syndrome and 11 168 patients had to experience the amputation of lower limb due to this condition...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871709/unusual-presentations-of-carney-complex-in-patient-with-a-novel-prkar1a-mutation
#9
Safak Akin, Senem Noyan, Selcuk Dagdelen, Ilhan Pasaoglu, Volkan Kaynaroglu, Melike Mut Askun, Cenk Yucel Bilen, Hayyam Kiratli, Dilek Ertoy Baydar, Sevgen Onder, Cenk Sokmensuer, Kudret Aytemir, Gul Erkin, Pinar Ozgen Kiratli, Mehmet Alikasifoglu, Tomris Erbas
Carney Complex (CNC) is a multiple neoplasia syndrome characterized by skin tumors and pigmented lesions, myxomas, and various endocrine tumors. The aim of this case report was to describe a case of CNC with a novel PRKAR1A mutation. A man aged 46 years with a medical history of surgery for cardiac myxomas at the age of 39 was admitted to our hospital because of four newly-developed heart masses. The histologic examination confirmed cardiac myxomas. He had many presentations of CNC such as growth hormone (GH) and prolactin (PRL)-secreting mixed pituitary adenoma, benign thyroid nodule, large-cell calcifying Sertoli cell tumor (LCCST), and superficial angiomyxoma...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871708/pituitary-hyperplasia-mimicking-macroadenoma-associated-with-primary-hypothyroidism-in-a-patient-with-selective-l-thyroxine-malabsorption
#10
Andrea Sansone, Massimiliano Sansone, Walter Vena, Radha Tedone, Francesco Romanelli
We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia. We performed thyroxine absorption tests to diagnose the malabsorption and to evaluate the best therapeutic intervention. Once assessed a correct therapy lowering TSH, we observed the regression of pituitary mass confirming our diagnosis of secondary pituitary hyperplasia. We suggest to evaluate any possible reason for thyroxine malabsorption and to consider the hypothesis of pituitary hyperplasia in the presence of pituitary mass together with overt hypothyroidism...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28871707/search-for-relevant-indications-for-selenium-supplementation-in-thyroid-diseases
#11
Katarzyna Wojciechowska-Durczynska, Andrzej Lewinski
Selenium plays a significant role in the thyroid function and its deficiency is considered by some authors to be a cause of thyroid disorders. The potential therapeutic influence of selenium supplementation in thyroid disease was investigated in several studies and some results were encouraging, however results were inconsistent and did not allow conclusion to be drawn. For that reason, we have performed a review study on relevance of selenium supplementation in thyroid disease. Till now, there is no strong evidence that selenium supplementation leads to clinical improvement in the course of autoimmune thyroiditis, nodular goitre or thyroid cancer...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759191/effects-of-age-on-the-glucoregulatory-response-following-acute-glucoprivation-induced-by-2-deoxyglucose-2dg-in-the-adrenal-medulla-of-sprague-dawley-rats
#12
Nor Azura Muda, Hajira Ramlan, Hanafi A Damanhuri
OBJECTIVES: Impairment in glucose homeostasis is one of the factors that may alter the feeding drive, hunger and satiety signals, which essential to maintain a sufficient level of energy for daily activities especially among the elderly. Adrenal medulla is one of the important organs that involves in glucose homeostasis through secretion of catecholamines. The catecholamines biosynthesis pathway utilizes various enzymes and protein kinases. The aims of this study are to investigate the effects of age on the biosynthetic pathway of catecholamines in adrenal medulla by determining the level of blood glucose and blood catecholamines, the gene and protein expression of biosynthetic catecholamine enzymes (TH, DBH and PNMT) as well as protein kinase substrates that involved in the phosphorylation of TH in 2DG-induced rats...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759190/genetic-polymorphisms-and-serum-concentrations-of-adiponectin-and-resistin-in-anorexia-nervosa-and-healthy-controls-pilot-study
#13
Karolina Ziora-Jakutowicz, Janusz Zimowski, Katarzyna T Ziora, Joanna M Oswiecimska, Elzbieta Swietochowska, Piotr Gorczyca, Małgorzata Bednarska-Makaruk, Dominika Szczesniak, Filip Rybakowski
BACKGROUND: A possible role of adipokines in the regulation of body weight in patients with anorexia nervosa (AN) has been proposed. Polymorphisms in genes encoding adiponectin and resistin in AN have not been widely assessed, yet. OBJECTIVES: 1) Assessment the frequency of ADIPOQ c.45T>G, ADIPOQ c.276G>T polymorphisms in adiponectin and RETN c.62G>A, RETN c.-180C>G in resistin genes in AN patients and control group (C) 2) Analysis of correlation between these polymorphisms and serum ADP or RETN...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759189/carotid-intima-media-thickness-in-plaque-free-area-carotid-plaque-and-risk-of-ischemic-stroke-in-high-risk-population-of-north-china
#14
Wang Zhuang-Zhuang, Fang Ya-Lan, Wu Xiao-Wei, Li Chang-Xin, Zhang Wei, Li Yang, Niu Xiao-Yuan
OBJECTIVE: Stroke is the leading cause of mortality and acquired disability in adults in China. In this study, we investigated the role of carotid artery intima-media thickness (IMT) and carotid plaques in new ischemic stroke of high-risk population in North China. METHODS: The study was conducted in 4 towns in North China area. Subjects with three or more cardiovascular risk factors such as hypertension, dyslipidemia (or unknown), diabetes mellitus, currently smoking, over weight, family history of stroke, with a history of transient ischemic attack (TIA) and ischemic stroke were included in this study...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759188/selected-mechanical-paremeters-of-women-s-hair-in-the-caucasian-population
#15
Marie Skřontová, Lucie Šimkova, Václav Bittner, Bohumil Chalupa, Josef Zeman, Karel Jelen
OBJECTIVE: More parameters have been used for more detailed description of mechanical properties of human hair as a fibre than in analogous studies. All measured samples were taken from five different locations on the heads of 60 women of varied age. METHODS: For each hair, the diameter was determined optically and then the test in the Deform Type 2 testing machine was carried out. Deformation curves were obtained by testing 10 mm long samples up to the rupture point at constant temperature, humidity and constant crossbar speed of 2 mm/min...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759187/a-chinese-herbal-medicine-modified-guomin-decoction-influences-the-differentiation-of-cd4-t-cell-subsets-in-ova-induced-asthmatic-mice
#16
Lilan Qin, Yuying Lan, Jian Sun, Beiqi Zhang, Peitao Xie, Jinghui Zheng, Shuran Ma
OBJECTIVE: Modified Guomin Decoction (MGD) is an effective Chinese herbal medicine for treatment of various allergic diseases, especially allergic asthma. Its water decoction is conventionally used for treatment of allergic bronchitis in China. Up to date, the underlying mechanisms of this herbal combination have not been fully investigated yet. METHODS: In the in vivo study, the mice were treated with Chicken egg ovalbumin (OVA) and aluminum hydroxide gel as the classic allergic asthma animal model...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759186/endocrine-and-haemodynamic-stress-responses-to-an-arithmetic-cognitive-challenge
#17
Domenico Trico, Alberto Fanfani, Francesca Varocchi, Giampaolo Bernini
OBJECTIVE: We aimed at developing and validating a simple, highly repeatable computer-based tool, which could be employed to simulate the effects of an acute mental stress on endocrine and haemodynamic stress responses. METHODS: Fifteen subjects underwent a mental cognitive challenge, employing an ad hoc designed web tool (available at http://bagame.altervista.org) that proposed a series of random arithmetic operations (addictions or subtractions) between one- to three-digit numbers for 10 minutes...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759183/co-administration-of-cyclosporin-a-and-ondansetron-decreases-transient-local-cerebral-ischemic-injury-in-the-mouse
#18
Michihiro Murozono, Ryouichi Miyashita, Akiko Takeda, Kunio Ynagita, Eiichi Sato, Yukihiko Ogiwara
OBJECTIVES: Several studies indicate that cyclosporin A has a protective effect against brain infarction. In this study, we aimed to determine if co-administration of cyclosporin A and ondansetron could reduce damage caused by cerebral ischemia. METHODS: ICR (Charles River Laboratories) mice were subjected to transient focal cerebral ischemia and divided into 4 groups (O, V, C, and Mix). Immediately after reperfusion, each ligand was administered intravenously through the external jugular vein...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759182/intima-media-thickness-of-common-carotids-and-abdominal-aorta-in-children-and-adolescents-with-congenital-adrenal-hyperplasia-due-to-21-hydroxylase-deficiency-in-relation-to-their-genotypes
#19
Dominika Janus, Malgorzata Wojcik, Katarzyna Tyrawa, Magdalena Janeczko, Mirosław Bik-Multanowski, Jerzy B Starzyk
BACKGROUND: Patients with congenital adrenal hyperplasia (CAH) are at risk of vascular and metabolic complications due to steroid therapy and increased adrenal androgens exposure. OBJECTIVE: of the study was to evaluate the relation between patient's genotype and (1) intima media thickness of abdominal aorta (AIMT) and common carotid arteries (CIMT) and (2) metabolic profile. MATERIAL AND METHODS: In 71 patients (27 boys) aged from 1.5 to 17...
July 2, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28759185/serum-fgf21-in-girls-with-anorexia-nervosa-comparison-to-normal-weight-and-obese-female-adolescents
#20
Agata Mikolajczak, Joanna M Oswiecimska, Elzbieta Swietochowska, Wojciech Roczniak, Katarzyna T Ziora
BACKGROUND: Fibroblast growth factor 21 (FGF21) is a hepatokine, myokine and adipokine of a potent influence to energy homeostasis. Data according its serum concentrations in AN are contradictory. OBJECTIVES: Analysis of serum FGF21 in girls with acute anorexia nervosa and comparison the results with normal weight and obese female adolescents considering their nutritional status, carbohydrate and lipid metabolism. METHODS: Serum FGF21 concentrations were evaluated using commercially available ELISA kit in 32 Polish girls with restrictive AN (AN), 29 girls with obesity (O) and 21 healthy controls (C)...
July 2017: Neuro Endocrinology Letters
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