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Neuro Endocrinology Letters

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https://www.readbyqxmd.com/read/28456150/structural-and-construct-validity-of-the-czech-version-of-the-pittsburgh-sleep-quality-index-in-chronic-insomnia
#1
Daniela Dudysová, Ivana Malá, Karolína Mladá, Elizaveta Saifutdinova, Jana Koprivova, Peter Sos
OBJECTIVES: The Pittsburgh Sleep Quality Index (PSQI) is one of the widely used and recommended measures of assessing sleep quality in chronic insomnia; however certain psychometric properties of the questionnaire are still unknown in this group of patients. The present study aimed to examine the internal consistency, and structural and convergent validity of the Czech version of the PSQI in chronic insomnia patients. The usefulness of the standard and alternative scoring systems was also investigated in relation to symptoms of sleepiness, insomnia, depression, and anxiety...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28456149/plasma-chemerin-in-young-untrained-men-association-with-cardio-metabolic-traits-and-physical-performance-and-response-to-intensive-interval-training
#2
Nejmeddine Ouerghi, Mohamed Kacem Ben Fradj, Marwa Khammassi, Moncef Feki, Naziha Kaabachi, Anissa Bouassida
OBJECTIVES: Chemerin is an adipose tissue-derived adipokine thought to decrease insulin sensitivity and increase cardiometabolic risk. This study aimed to assess the association of chemerin with cardiometabolic risk and physical performance and examine its response to high-intensity interval training (HIIT). METHODS: Eighteen young men have been applied a HIIT program during 8 weeks. Plasma chemerin together with several cardiometabolic factors and physical performance indices were determined before and after the training program...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28456148/impact-of-emotional-disorders-on-semen-quality-in-men-treated-for-infertility
#3
Artur Wdowiak, Agnieszka Bień, Grażyna Iwanowicz-Palus, Marta Makara-Studzińska, Iwona Bojar
OBJECTIVE: Semen quality depends on factors such as lifestyle, environment, and hormone secretion. OBJECTIVE: The purpose of the study was to assess the correlation between emotional disorders and the secretion of selected hormones, and to assess the impact of these disorders on semen quality. METHODS: The study covered 60 fertile and 112 subfertile males. The sperm was obtained by masturbation, and examined directly after liquidation according to the 2010 criteria of the World Health Organization...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28456147/tyrosine-hydroxylase-gene-expression-is-facilitated-by-alcohol-followed-by-the-degradation-of-the-protein-by-ubiquitin-proteasome-system
#4
Ichiro Kawahata, Gutierrez Rico Evelyn, Xu Huinan, Shiori Ohtaku, Yoshihisa Tomioka, Tohru Yamakuni
OBJECTIVES: Alcohol intake induces brief periods of euphoria; however, its continuous consumption can lead the development of alcohol tolerance. The euphoria, an intense feeling of wellbeing, is deeply associated with dopamine. Dopamine biosynthesis is strictly regulated by tyrosine hydroxylase (TH), a rate-limiting enzyme of dopamine. The aim of this study was to examine the transient or chronic effects of ethanol treatment on TH protein level in vitro. METHODS: Cultured primary mesencephalic neurons were prepared and exposed to 100 mM ethanol for 48 hours or 168 hours...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28456146/comparative-effects-of-a-fixed-polypodium-leucotomos-pomegranate-combination-versus-polypodium-leucotomos-alone-on-skin-biophysical-parameters
#5
Enzo Emanuele, Marco Bertona, Marco Biagi
OBJECTIVES: Polypodium leucotomos extract is a commonly used systemic photoprotective agent. In an exploratory fashion, the current study aimed to compare the effects of oral supplementation with a fixed Polypodium leucotomos/pomegranate combination (PPmix®) versus Polypodium leucotomos alone (Fernblock®) on skin biophysical parameters of Caucasian adults. METHODS: Forty healthy adult volunteers (20 males and 20 females; mean age: 37.2±5.5 years) were randomized in a 1:1 fashion to a fixed Polypodium leucotomos/pomegranate combination (480 mg/day; n=20) or Polypodium leucotomos alone (480 mg/day; n=20) for 3 months...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28456145/autophagy-plays-beneficial-effect-on-diabetic-encephalopathy-in-type-2-diabetes-studies-in-vivo-and-in-vitro
#6
Yu-Hong Jing, Lang Zhang, Li-Ping Gao, Chu-Chu Qi, Dan-Dan Lv, Yan-Feng Song, Jie Yin, De-Gui Wang
OBJECTIVES: The hypothalamus regulates metabolism and feeding behavior by perceiving the levels of peripheral insulin. However, little is known about the hypothalamic changes after aberrant metabolism. In this study, we investigated the changes of insulin and autophagy relevant signals of hypothalamus under diabetes mellitus. METHODS: C57B/L mice were injected with low-dose streptozotocin (STZ) and fed with high-fat diet to induce type 2 diabetes mellitus. In vitro, PC12 cells were treated with oleic acid to mimic lipotoxicity...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28456144/effects-of-venlafaxine-and-chronic-unpredictable-stress-on-behavior-and-hippocampal-neurogenesis-of-rat-dams
#7
Kristina Belovicova, Eszter Bogi, Romana Koprdova, Eduard Ujhazy, Mojmir Mach, Michal Dubovicky
OBJECTIVE: Epidemiological studies strongly support the theory that stressful life events play an important role in the etiology of depression. The mechanism of chronic stress induced depression involves a number of systems. Chronic stress represents a serious health issue especially during pregnancy and lactation. In this sensitive period, stress can lead to changes in emotion and cognitive behavior both of the mothers and the offspring. It is thus necessary to properly manage stress events during gestation...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28456143/a-first-case-of-adrenomyeloneuropathy-with-mutation-y174s-of-the-adrenoleukodystrophy-gene
#8
Yukio Horikawa, Mayumi Enya, Nobuaki Yoshikura, Junichi Kitagawa, Shigeo Takashima, Nobuyuki Shimozawa, Jun Takeda
The patient first noticed spasticity and weakness in his legs. He was diagnosed with chronic myelogenous leukemia (CML); the symptoms were attributed to neuropathy associated with CML. By treatment with dasatinib, he achieved complete hematological remission, but his difficulty in walking was not improved. His neurological symptom worsened together with an increase in body temperature and then disappeared together with a normalized body temperature, which may be attributed to the Uhthoff's phenomenon often observed in multiple sclerosis...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28456142/endogenous-glucocorticoids-role-in-the-etiopathogenesis-of-alzheimer-s-disease
#9
Rosaliana Libro, Placido Bramanti, Emanuela Mazzon
Endogenous glucocorticoids (eGCs) are steroid hormones with a wide spectrum of physiological effects. However, enhanced basal eGCs levels have been observed in patients affected by Alzheimer's disease (AD) and they have been correlated with dysregulation of the hypothalamic-pituitary-adrenocortical axis, hippocampal degeneration and reduced cognitive/memory performance. Therefore, it has been proposed that elevated concentration of eGCs might have a role in AD pathogenesis. AD is the most common form of dementia, characterized by the pathological accumulation of two proteins: the Amyloid Beta (Aβ) and the microtubule-associated protein tau in the neurons of the hippocampus and prefrontal cortex...
February 15, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28326753/effects-of-essential-oil-exposure-on-salivary-estrogen-concentration-in-perimenopausal-women
#10
Kazuyuki Shinohara, Hirokazu Doi, Chizu Kumagai, Erika Sawano, Wataru Tarumi
OBJECTIVES: The menopausal transition is the time from the onset of menstrual changes until one year after the final menstrual period. During this phase, perimenopausal women experience a variety of health-related symptoms, which seemingly derive from declining level of estrogen secretion. It has long been recognized that some essential oils have the efficacy of alleviating menopausal symptoms. On the basis of this, it is possible that these essential oils have the potency to facilitate estrogen secretion in women...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28326752/minimal-role-of-comorbid-personality-disorder-on-the-quality-of-life-in-patients-with-anxiety-spectrum-disorders
#11
Dana Kamaradova, Klara Latalova, Jan Prasko, Ales Grambal, Zuzana Sigmundova, Petra Kasalova, Snezana Cakirpaloglu
OBJECTIVES: There is no consensus on the definition of Quality of life (QoL). It is considered to be comprised of both psychological and somatical well-being. A variety of tools has been developed to measure subjective and objective (QoL). A number of factors, including demographical and medical may have an impact on QoL. The aim of our study was to compare the QoL in selected anxiety disorders and evaluate the influence of comorbid personality disorder. METHOD: We evaluated data from 278 patients suffering from social phobia, panic disorder and/or agoraphobia, adjustment disorder, generalized anxiety disorder and obsessive-compulsive disorder...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28326751/assessment-of-body-surface-potential-mapping-in-diabetic-patients-with-recognized-depression
#12
Anna Janocha, Marek Bolanowski, Krzysztof Małyszczak, Witold Pilecki, Robert Skalik, Krystyna Laszki-Szczachor, Dariusz Kalka, Małgorzata Sobieszczanska
OBJECTIVES: Parameters of body surface potential mapping (BSPM) in DM II patients are significantly different comparing with healthy non-diabetic subjects. Hypothesis that these changes are more pronounced in DM II patients with depression was tested in the present study. For this purpose, analysis of the relationship between the Int-QRST (isointegral) maps distribution and the depressive symptoms intensification, as well interrelation between depressive and diabetic symptoms were performed...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28326750/measuring-hope-standardization-of-the-czech-version-of-the-adult-dispositional-hope-scale-in-healthy-adults
#13
Marie Ociskova, Irena Sobotkova, Jan Prasko, Vladimir Mihal
OBJECTIVES: Hope is an important factor that influences mental state of individuals and efficacy of systematic and supportive psychotherapy. The goal of the study was to translate the Adult Dispositional Hope Scale (ADHS) to Czech, evaluate its psychometric properties and create norms to interpret the scale scores. METHODS: The scale consists of twelve items. Four items assess the ability of pathway thinking, four items measure agency, and the remaining four items are fillers that are not interpreted...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28326749/a-case-of-autoimmune-polyendocrine-syndrome-type-i-with-strong-positive-gad-antibody-titer-followed-up-with-glucose-tolerance-measured-by-oral-glucose-tolerance-test
#14
Rie Murakami, Toshihide Kawai, Shu Meguro, Matsuhiko Hayashi, Hiroshi Itoh
A 26-year-old Japanese woman presented with adrenal insufficiency, and treatment was started with cortisone and fludrocortisone in 1975. A few years later, she presented with hypoparathyroidism and was diagnosed with autoimmune polyendocrine syndrome type I (APS I), and treatment with calcium and alfacalcidol was started. She was found to have subacute thyroiditis and relative adrenal failure in 2006. Her condition remained stable under treatment with cortisone, fludrocortisone, levothyroxine, calcium lactate, precipitated calcium carbonate and alfacalcidol...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28326748/carcionoid-of-the-appendix-in-pregnant-woman-case-report-and-literature-review
#15
Szymon Piatek, Malgorzata Gajewska, Grzegorz Panek, Miroslaw Wielgos
Neuroendocrine neoplasms are detected very rarely in pregnant women. The following is a case report of carcinoid tumor of the appendix diagnosed in 28 year-old woman at 25th week of gestation. The woman delivered spontaneously a healthy baby at the 38th week of gestation. She did not require adjuvant therapy with somatostatin analogues. The patient remained in remission. There are not established standards of care due to the very rare incidence of carcinoid tumors in pregnancy. A review of the literature related to management and prognosis in such cases was done...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28326747/laboratory-methods-for-diagnostics-of-hiv-infection-and-hiv-associated-neuroinfections
#16
Pavol Beno, Alzbeta Kaiglova, Martin Samohyl
HIV Infection resulting in AIDS remains serious global public health problem. In the fight with the global health problem plays a key role a simple, reliable and fast diagnostics. An important method in diagnostics is the identification and detection of viral capside p24 antigen levels. Fourth generation tests for the diagnostics of HIV infection simultaneously detect the presence of HIV antibodies and p24 antigen. Based on the monitoring of CD4 count, we can estimate the stage in which the infection is, and we can also suggest a therapeutic approach...
January 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28263542/smartphone-based-colorimetric-detection-of-glutathione
#17
Irena Vobornikova, Miroslav Pohanka
OBJECTIVES: Glutathione belongs to the family of small-molecular weight antioxidants like ascorbic acid, cysteine, α-tocopherol, uric acid, etc. These molecules play important role in the neutralization of free radicals and reactive oxygen species (ROS). Oxidative stress may lead to ageing and the development of large scale of pathological states of organism. This low molecular weight antioxidant´s level can alter under pathological conditions from reduced (GSH, thiols) to oxidized (oxidized glutathione -GSSG, disulfides) form...
December 18, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28263541/phone-camera-detection-of-glucose-blood-level-based-on-magnetic-particles-entrapped-inside-bubble-wrap
#18
Pavla Martinkova, Miroslav Pohanka
OBJECTIVES: Glucose is an important diagnostic biochemical marker of diabetes but also for organophosphates, carbamates, acetaminophens or salicylates poisoning. Hence, innovation of accurate and fast detection assay is still one of priorities in biomedical research. METHODS: Glucose sensor based on magnetic particles (MPs) with immobilized enzymes glucose oxidase (GOx) and horseradish peroxidase (HRP) was developed and the GOx catalyzed reaction was visualized by a smart-phone-integrated camera...
December 18, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28263540/alternative-methods-in-vitro-for-screening-of-endocrine-disruptors
#19
Markéta Dvořáková, Kristina Kejlová, Hana Bendová, Marian Rucki, Pavel Kohout, Adam Vavrouš, Dagmar Jírová
OBJECTIVES: The aim of this study was to compare in silico data with results obtained in two alternative in vitro methods; and to investigate the potential endocrine activity of bisphenol A analogues. This article contributes to recent findings and brings up-to-date information on development of EU legislation and in vitro testing methods of endocrine disruption. METHODS: In silico approach based on the OECD QSAR Toolbox was used for prediction of potential ligands of human estrogen receptor α...
December 18, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28263539/celecoxib-is-an-inhibitor-of-enzyme-acetylcholinesterase
#20
Miroslav Pohanka
OBJECTIVES: Celecoxib is a nonsteroidal anti-inflammatory drug inhibiting enzyme cyclooxygenase-2 (COX-2). The drug was introduced in 1990s. In the work presented here, affinity of celecoxib to enzyme acetylcholinesterase (AChE) is inferred. METHODS: Inhibition of human AChE by celecoxib was tested using standard spectrophotometric Ellman´s method and extrapolation of experimental data by Dixon plot. Interaction between AChE and celecoxib was also predicted by molecular docking using Swiss dock software...
December 18, 2016: Neuro Endocrinology Letters
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