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Takuya Hori, Takaki Nedachi, Hiroshi Suzuki, Shinji Harakawa
We recently suggested that an increase in the plasma glucocorticoid (GC) level in immobilized mice is suppressed by a 50-Hz electric field (EF) in an EF strength-dependent manner. The present study aimed to assess the anti-stress effect of EFs in three scenarios: exposure to an EF of either 50 or 60 Hz, which are the standard power frequencies in most regions; varying levels of environmental brightness during EF exposure; complete or partial shielding of the mouse from the EF. We compared the GC levels and blood parameters among control, EF-alone, immobilization-alone, and co-treatment groups...
August 9, 2018: Bioelectromagnetics
(no author information available yet)
No abstract text is available yet for this article.
September 2018: Bioelectromagnetics
Chuan Sun, Xiaoxia Wei, Aziguli Yimaer, Zhengping Xu, Guangdi Chen
Extremely low frequency magnetic field (ELF-MF) has been classified as a possible carcinogen to humans by the International Agency for Research on Cancer [2002]. However, debate on the genotoxic effects of ELF-MF has continued due to lack of sufficient experimental evidence. Ataxia telangiectasia mutated (ATM) plays a central role in DNA damage repair; its deficiency can result in cellular sensitivity to DNA-damaging agents. To evaluate the genotoxicity of ELF-MF, we investigated the effects of 50 Hz MF on DNA damage in ATM-proficient (Atm+/+ ) mouse embryonic fibroblasts (MEFs) and ATM-deficient (Atm-/- ) MEFs, a radiosensitive cell line...
September 2018: Bioelectromagnetics
James C Lin
No abstract text is available yet for this article.
September 2018: Bioelectromagnetics
Chris M Valdez, Ronald Barnes, Caleb C Roth, Erick Moen, Bennett Ibey
Nanosecond electric pulse (nsEP) exposure generates an array of physiological effects. The extent of these effects is impacted by whether the nsEP is a unipolar (UP) or bipolar (BP) exposure. A 600 ns pulse can generate 71% more YO-PRO-1 uptake compared to a 600 ns + 600 ns pulse exposure. This observation is termed "bipolar cancellation" (BPC) because despite the BP nsEP consisting of an additional 600 ns pulse, it generates reduced membrane perturbation. BPC is achieved by varying pulse amplitudes, and symmetrical and asymmetric pulse widths...
September 2018: Bioelectromagnetics
Stacey L Martens, Caleb C Roth, Bennett L Ibey
Cell-circuit models have suggested that nanosecond pulsed electric fields (nsPEFs) can disrupt intracellular membranes including endoplasmic reticulum (ER), mitochondria, and/or nucleus thereby inducing intrinsic apoptotic pathways. Therefore, we hypothesized that the unfolded protein response (UPR) would be activated, due to the fluctuations of ionic concentrations, upon poration of the ER membrane. Quantitative real-time polymerase chain reaction was utilized to measure changes in messenger RNA (mRNA) expression of specific ER stress genes in adult human dermal fibroblast (HDFa) cells treated with tunicamycin (TM) (known ER stress inducer) and cells exposed to nsPEFs (100, 10-ns pulses at 150 kV/cm delivered at a repetition rate of 1 Hz)...
September 2018: Bioelectromagnetics
Hui-Meng Lu, Xiao-Li Lu, Jia-Hui Zhai, Ren-Bin Zhou, Yong-Ming Liu, Wei-Hong Guo, Chen-Yan Zhang, Peng Shang, Da-Chuan Yin
Large gradient high magnetic field (LG-HMF) is a powerful tool to study the effects of altered gravity on organisms. In our study, a platform for the long-term culture of aquatic organisms was designed based on a special superconducting magnet with an LG-HMF, which can provide three apparent gravity levels (µ g, 1 g, and 2 g), along with a control condition on the ground. Planarians, Dugesia japonica, were head-amputated and cultured for 5 days in a platform for head reconstruction. After planarian head regeneration, all samples were taken out from the superconducting magnet for a behavioral test under geomagnetic field and normal gravity conditions...
September 2018: Bioelectromagnetics
Maraelys M González, Dasha F Morales, Luis E B Cabrales, Daniel J Pérez, Juan I Montijano, Antonio R S Castañeda, Victoriano G S González, Oscar O Posada, Janet A Martínez, Arlem G Delgado, Karina G Martínez, Mayrel L Mon, Kalet L Monzón, Héctor M C Ciria, Emilia O Beatón, Soraida C A Brooks, Tamara R González, Manuel V Jarque, Miguel A Ó Mateus, Jorge L G Rodríguez, Enaide M Calzado
Electrochemical treatment has been suggested as an effective alternative to local cancer therapy. Nevertheless, its effectiveness decreases when highly aggressive primary tumors are treated. The aim of this research was to understand the growth kinetics of the highly aggressive and metastatic primary F3II tumor growing in male and female BALB/c/Cenp mice under electrochemical treatment. Different amounts of electric charge (6, 9, and 18 C) were used. Two electrodes were inserted into the base, perpendicular to the tumor's long axis, keeping about 1 cm distance between them...
September 2018: Bioelectromagnetics
Varshini Karthik, T Rama Rao
Wearable electronics have become the norm over the last few years. Extensive use of wearable wireless devices (WWD) in greater proximity to the body has increased concern about potential biological effects due to the interaction of human tissues with electromagnetic (EM) fields. Human tissues absorb radiofrequency (RF) waves that are capable of affecting energy states at a molecular level, leading to unsafe effects. Remarkably, thermal effect due to the absorption of RF waves is a better biological manifestation than traditional specific absorption rate (SAR) values...
September 2018: Bioelectromagnetics
Galina Khokhlova, Tatiana Abashina, Nataliya Belova, Victor Panchelyuga, Alexey Petrov, Fernanda Abreu, Mikhail Vainshtein
Bacteria are the simplest model of living organisms and thus are a convenient object for magnetobiological research. This paper describes some effects of combined magnetic fields (CMFs) on the bacterium Rhodospirillum rubrum strain VKM B-1621, which is not a pathogen but was selected due to its wide spectrum of growth abilities. The authors chose magnetic field-resonant phosphorus and iron (Fe3+ ) because P-containing biochemical compounds (standard abbreviations PP1 , AMP, ADP, ATP) provide energy flows in bacteria while iron could take part in formation of magnetosensitive intracellular inclusions...
September 2018: Bioelectromagnetics
(no author information available yet)
No abstract text is available yet for this article.
July 2018: Bioelectromagnetics
Lin-Qing Yuan, Can Wang, Kun Zhu, Hua-Mei Li, Wei-Zhong Gu, Dong-Ming Zhou, Jia-Qi Lai, Duo Zhou, Yao Lv, Santi Tofani, Xi Chen
Certain magnetic fields (MF) have potential therapeutic antitumor effect whereas the underlying mechanism remains undefined. In this study, a well-characterized MF was applied to two common childhood malignancies, nephroblastoma and neuroblastoma. This MF has a time-averaged total intensity of 5.1 militesla (mT), and was generated as a superimposition of a static and an extremely low frequency (ELF) MF in 50 Hertz (Hz). In nephroblastoma and neuroblastoma cell lines including G401, CHLA255, and N2a, after MF exposure of 2 h per day, the cell viability decreased significantly after 2 days...
July 2018: Bioelectromagnetics
Chiara Agliassa, Ravishankar Narayana, Cinzia M Bertea, Christopher T Rodgers, Massimo E Maffei
Variations in magnetic field (MF) intensity are known to induce plant morphological and gene expression changes. In Arabidopsis thaliana Col-0, near-null magnetic field (NNMF, i.e., <100 nT MF) causes a delay in the transition to flowering, but the expression of genes involved in this response has been poorly studied. Here, we showed a time-course quantitative analysis of the expression of both leaf (including clock genes, photoperiod pathway, GA20ox, SVP, and vernalization pathway) and floral meristem (including GA2ox, SOC1, AGL24, LFY, AP1, FD, and FLC) genes involved in the transition to flowering in A...
July 2018: Bioelectromagnetics
Beatrice Siervo, Maria Sole Morelli, Luigi Landini, Valentina Hartwig
The use of wireless communication devices, such as tablets or laptops, is increasing among children. Only a few studies assess specific energy absorption rate (SAR) due to exposure from wireless-enabled tablets and laptops, in particular with Worldwide Interoperability for Microwave Access (WiMax) technology. This paper reports the estimation of the interaction between an E-shaped patch antenna (3.5 GHz) and human models, by means of finite-difference time-domain (FDTD) method. Specifically, four different human models (young adult male, young adult female, pre-teenager female, male child) in different exposure conditions (antenna at different distances from the human model, in different positions, and orientations) were considered and whole-body, 10 and 1 g local SAR and magnetic field value (Bmax) were evaluated...
July 2018: Bioelectromagnetics
Juhani Multanen, Arja Häkkinen, Pauli Heikkinen, Hannu Kautiainen, Sirpa Mustalampi, Jari Ylinen
Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12-week treatment period with an active Bio-Electro-Magnetic-Energy-Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order...
July 2018: Bioelectromagnetics
Eun-Cheol Kim, Jaesuh Park, Gunwoo Noh, Su-Jung Park, Kwantae Noh, Il-Keun Kwon, Su-Jin Ahn
Although we recently demonstrated that static magnetic fields (SMFs) of 3, 15, and 50 mT stimulate osteoblastic differentiation, the effects of SMFs on osteoclastogenesis are still poorly understood. This study focused on the suppressive effects of SMFs on receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclastogenesis and bone resorption. Direct SMFs inhibit RANKL-induced multinucleated osteoclast formation, tartrate-resistant acid phosphatase activity, and bone resorption in mouse bone marrow-derived macrophage cells...
July 2018: Bioelectromagnetics
Ling Guo, Jun-Ping Zhang, Ke-Ying Zhang, Huan-Bo Wang, Huan Wang, Guang-Zhou An, Yan Zhou, Guo-Lin Meng, Gui-Rong Ding
To investigate the effects of 1.8 GHz radiofrequency (RF) field on bone microstructure and metabolism of femur in mice, C57BL/6 mice (male, age 4 weeks) were whole-body exposed or sham exposed to 1.8 GHz RF field. Specific absorption rates of whole body and bone were approximately 2.70 and 1.14 W/kg (6 h/day for 28 days). After exposure, microstructure and morphology of femur were observed by microcomputed tomography (micro-CT), Hematoxylin and Eosin (HE) and Masson staining. Subsequently, bone parameters were calculated directly from the reconstructed images, including structure model index, bone mineral density, trabecular bone volume/total volume, connectivity density, trabecular number, trabecular thickness, and trabecular separation...
July 2018: Bioelectromagnetics
Dongmei Wang, Ze Wang, Lei Zhang, Zhiyuan Li, XiaoFei Tian, Jun Fang, Qingyou Lu, Xin Zhang
Mitochondrion is the major cellular energy producing organelle that is at the boundary between chemical reactions and physical processes. Although mitochondria have been shown to be affected by physical methods such as nonthermal plasma, whether static magnetic field (SMF) could also affect them is still unclear. Here we used rat adrenal PC12 cells to compare SMFs of different intensities for their effects on ATP (adenosine-5'-triphosphate), the major energy source produced by mitochondria, which is essential for various cellular processes...
July 2018: Bioelectromagnetics
Javier Torres, Alfredo Socorro, Eduard Hincapié
In order to analyze the treatment of seeds with homogeneous static magnetic field on the water adsorption process, an experimental-theoretical study of hygroscopic equilibrium in maize seeds (Zea mays L. cv. ICAV305) was carried out. Four treatments with magnetic induction of 80.0, 120.0, 160.0, and 200.0 mT were applied for 10 min, and there was a control group without treatment. The doses were selected because they showed a decrease in mean germination time. Treated seeds were subjected to an environment with a stable temperature of 30...
July 2018: Bioelectromagnetics
Yashar Bashirzadeh, Jonathan Poole, Shizhi Qian, Venkat Maruthamuthu
Electrotaxis-the directional migration of cells in response to an electric field-is most evident in multicellular collectives and plays an important role in physiological contexts. While most cell types respond to applied electric fields of the order of a Volt per centimeter, our knowledge of the factors influencing this response is limited. This is especially true for collective cell electrotaxis, in which the subcellular migration response within a cell has to be coordinated with coupled neighboring cells...
May 2018: Bioelectromagnetics
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