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Lasers in Surgery and Medicine

Guilherme J P L de Oliveira, Maurício A T Aroni, Marcell C Medeiros, Elcio Marcantonio, Rosemary A C Marcantonio
OBJECTIVE: The aim of this study was to evaluate the effect of low-level laser therapy (LLLT) on the healing of biomaterial graft areas (i.e., coagulum, deproteinized bovine bone, and biphasic ceramics comprising hydroxyapatite and β-tricalcium phosphate). MATERIAL AND METHODS: Ninety rats were divided into two groups according to laser irradiation use (λ 808 nm, 100 mW, φ ∼600 μm, seven sessions with 28 J of irradiation dose in total): a laser group and a control group...
January 13, 2018: Lasers in Surgery and Medicine
David J Carpenter, Mirabelle B Sajisevi, Nikita Chapurin, Clifford Scott Brown, Tracy Cheng, Gregory M Palmer, Daniel S Stevenson, Caroline L Rao, Russell P Hall, Charles R Woodard
OBJECTIVE: Optical spectroscopy offers a noninvasive alternative to biopsy as a first-line screening tool for suspicious skin lesions. This study sought to define several optical parameters across malignant and benign tissue types. STUDY DESIGN: Prospective pilot trial utilizing the Zenalux IM1 optical spectroscopy device from April 2016 to February 2017. For each skin lesion, provider pre-biopsy probability of malignancy was compared to histolopathologic diagnosis...
January 13, 2018: Lasers in Surgery and Medicine
Isabela T Jones, Monique J Vanaman Wilson, Isabella Guiha, Douglas C Wu, Mitchel P Goldman
BACKGROUND: Cryolipolysis is a non-invasive method of body shaping that has been used for male pseudogynecomastia. However, traditional vacuum suction cryolipolysis requires a minimum pinchable fat layer which may not always be present in this area. OBJECTIVE: To evaluate the efficacy and safety of a conformable surface cryolipolysis applicator for the reduction of male pseudogynecomastia. MATERIALS AND METHODS: Ten male subjects with pseudogynecomastia received two cycles of cryolipolysis to the breast 6 weeks apart...
January 13, 2018: Lasers in Surgery and Medicine
Myeongjin Kim, Hyejin Kim, Hyun Wook Kang
BACKGROUND AND OBJECTIVE: Hypertrophic scar (HTS) results from a connective tissue reaction to trauma, inflammation, surgery, or burn on skin. In spite of various techniques for wound generation, the degree of scar in animal models after healing is still unpredictable and less reproducible. The objective of the current study was to identify the appropriate method to create the maximal HTS tissue in a reliable manner by comparing three different methods in vivo. MATERIALS AND METHODS: A 27 ICR mice were tested for the in vivo evaluations...
January 11, 2018: Lasers in Surgery and Medicine
Anthony M Rossi, Nina R Blank, Kishwer Nehal, Stephen Dusza, Erica H Lee
OBJECTIVE: To evaluate the effects of laser monotherapy on quality of life in breast cancer patients with chronic radiation dermatitis. STUDY DESIGN: A prospective, IRB-approved study was conducted at Memorial Sloan Kettering Cancer Center. Breast cancer patients with chronic radiation dermatitis completed health-related quality of life (HR-QOL) questionnaires before and after laser monotherapy for radiation-induced breast telangiectasias (RIBT). METHODS: After informed consent, all patients were issued the Skindex-16 and Breast-Q Adverse Effects of Radiation HR-QOL questionnaires prior to receiving laser treatment...
December 20, 2017: Lasers in Surgery and Medicine
Maximilian Eisel, Stephan Ströbl, Thomas Pongratz, Frank Strittmatter, Ronald Sroka
OBJECTIVES: Ureteroscopic laser lithotripsy is an important and widely used method for destroying ureter stones. It represents an alternative to ultrasonic and pneumatic lithotripsy techniques. Although these techniques have been thoroughly investigated, the influence of some physical parameters that may be relevant to further improve the treatment results is not fully understood. One crucial topic is the propulsive stone movement induced by the applied laser pulses. To simplify and speed up the optimization of laser parameters in this regard, a video tracking method was developed in connection with a vertical column setup that allows recording and subsequently analyzing the propulsive stone movement in dependence of different laser parameters in a particularly convenient and fast manner...
December 20, 2017: Lasers in Surgery and Medicine
Seonguk Min, Ji Young Yoon, Seon Yong Park, Jungyoon Moon, Hyuck Hoon Kwon, Dae Hun Suh
BACKGROUND: Platelet-rich plasma (PRP) which contains large amounts of growth factors has been tried to enhance therapeutic efficacy of laser treatment for acne scar with unknown underlying mechanism. OBJECTIVES: The present study was conducted to investigate the molecular mechanism of increased clinical efficacy of PRP when combined with fractional laser treatment for treating acne scars. METHODS: Subjects with mild to moderate acne scars were treated with two sessions of fractional CO2 laser therapy given with and without co-administration of PRP...
December 20, 2017: Lasers in Surgery and Medicine
Christopher Zachary
No abstract text is available yet for this article.
December 14, 2017: Lasers in Surgery and Medicine
Roy G Geronemus
No abstract text is available yet for this article.
December 12, 2017: Lasers in Surgery and Medicine
Timothy M Baran
OBJECTIVES: The goal of this study was to compare tumor response to Photofrin® photodynamic therapy using intravenous and intratumoral injection of photosensitizer. Systemic skin photosensitivity and photosensitizer distribution were also compared between the two delivery methods. METHODS: SCCVII tumors were initiated in the hind legs of female C3H mice and grown to a volume of ∼1,000 mm3 . Photofrin® was delivered intravenously via the tail vein at a concentration of 2 mg/kg or intratumorally at concentrations ranging from 0...
December 7, 2017: Lasers in Surgery and Medicine
Risako Mikami, Koji Mizutani, Akira Aoki, Yukihiko Tamura, Kazuhiro Aoki, Yuichi Izumi
BACKGROUND AND OBJECTIVE: Low-level laser irradiation (LLLI) exerts various biostimulative effects, including promotion of wound healing and bone formation; however, few studies have examined biostimulation using blue lasers. The purpose of this study was to investigate the effects of low-level ultrahigh-frequency (UHF) and ultrashort-pulse (USP) blue laser irradiation on osteoblasts. STUDY DESIGN/ MATERIALS AND METHODS: The MC3T3-E1 osteoblast cell line was used in this study...
December 7, 2017: Lasers in Surgery and Medicine
Edward V Ross, Gary S Chuang, Arisa E Ortiz, Scott A Davenport
BACKGROUND: High concentrations of sub-micron nanoparticles have been shown to be released during laser hair removal (LHR) procedures. These emissions pose a potential biohazard to healthcare workers that have prolonged exposure to LHR plume. OBJECTIVE: We sought to demonstrate that cold sapphire skin cooling done in contact mode might suppress plume dispersion during LHR. METHODS: A total of 11 patients were recruited for laser hair removal...
December 7, 2017: Lasers in Surgery and Medicine
Tjeerd de Boorder, Hans B Brouwers, Herke Jan Noordmans, Peter A Woerdeman, Kuo S Han, Rudolf M Verdaasdonk
BACKGROUND AND OBJECTIVE: Endoscopic third ventriculostomy is used to treat hydrocephalus. Different laser wavelengths have been proposed for laser-assisted endoscopic third ventriculostomies over the last decades. The aim of this study was to evaluate Thulium laser endoscopic third ventriculostomy heat penetration in the surrounding environment of the floor of the third ventricle in an in vitro setting with visualization of thermal distribution. Subsequently 106 Thulium laser endoscopic third ventriculostomy procedures were retrospectively analyzed to demonstrate safety...
December 7, 2017: Lasers in Surgery and Medicine
Sogyong L Auh, Sanjana Iyengar, Alexandra Weil, Diana Bolotin, Todd V Cartee, Jeffrey S Dover, Ian A Maher, Joseph F Sobanko, Joel L Cohen, Emily Poon, Murad Alam
BACKGROUND AND OBJECTIVE: Noninvasive fat reduction appears effective, but there are various methods for quantifying changes. The objective of this review is to assess comparative utility measures of subcutaneous fat. STUDY DESIGN/MATERIALS AND METHODS: Articles describing noninvasive fat reduction were searched using MEDLINE, EMBASE, CINAHL and Scopus electronic databases on two dates (January 28, 2014 and February 16, 2016). Titles of studies and abstracts were screened for eligibility...
December 6, 2017: Lasers in Surgery and Medicine
Kwan S Park, Woo June Choi, Shaozhen Song, Jingjiang Xu, Ruikang K Wang
BACKGROUND AND OBJECTIVE: Wound healing involves a complex and dynamic biological process in response to tissue injury. Monitoring of the cascade of cellular events is useful for wound management and treatment. The aim of this study is to demonstrate the potential of multifunctional polarization-sensitive optical coherence tomography (PS-OCT) to longitudinally monitor the self-healing process in a murine cutaneous wound model. MATERIALS AND METHODS: A multi-functional PS-OCT system based on swept source OCT configuration (1,310 nm central wavelength) was designed to obtain simultaneously microstructural, blood perfusion, and birefringent information of a biological tissue in vivo...
November 30, 2017: Lasers in Surgery and Medicine
Christina A Banzhaf, Lynlee L Lin, Nhung Dang, Michael Freeman, Merete Haedersdal, Tarl W Prow
BACKGROUND: Ablative fractional laser (AFXL) is an acknowledged technique to increase uptake of topical agents in skin. Micro thermal ablation zones (MAZs) consist of ablated vertical channels surrounded by a coagulation zone (CZ). Laser scanning confocal microscopy (LSCM) images individual MAZs at 733 nm (reflectance confocal microscopy (RCM)). Further, LSCM can image sodium fluorescein (NaF) fluorescence with 488 nm excitation (fluorescence confocal microcopy (FCM)), a small hydrophilic test molecule (370 MW, log P -1...
November 29, 2017: Lasers in Surgery and Medicine
Leanna Souza-Barros, Ghaith Dhaidan, Mikko Maunula, Vaeda Solomon, Sharon Gabison, Lothar Lilge, Ethne L Nussbaum
OBJECTIVE: To examine the role of skin color and tissue thickness on transmittance, reflectance, and skin heating using red and infrared laser light. METHODS: Forty volunteers were measured for skin color and skin-fold thickness at a standardized site near the elbow. Transmittance, reflectance and skin temperature were recorded for energy doses of 2, 6, 9, and 12 Joules using 635 nm (36 mW) and 808 nm (40 mW) wavelength laser diodes with irradiances within American National Standards Institute safety guidelines (4...
November 27, 2017: Lasers in Surgery and Medicine
Elizabeth Geddes-Bruce, Selina S Hamill, Christopher B Zachary, Paul M Friedman
OBJECTIVES: To evaluate the long-term efficacy of treating nasal telangiectasias with the TRASER device. METHODS: Subjects from the TRASER efficacy analysis clinical trial were invited for a 1-year follow-up. Standardized photographs were taken to compare to baseline. The same clinical trial evaluator graded the subjects' current vessel clearance using the 5-point telangiectasia scale. The data was compiled and analyzed. RESULTS: Of the subjects with available follow-up data, 44% maintained "complete vessel clearance," 44% dropped down one grade to "almost complete vessel clearance," and 11% dropped down to "moderately clear vessel clearance...
November 24, 2017: Lasers in Surgery and Medicine
Bilgehan Sezgin Asena, Mahmut Kaskaloglu
PURPOSE: To compare two different fragmentation patterns in femtosecond laser-assisted cataract surgery (FLACS) in terms of phaco values, postoperative endothelial cell count (ECC) and corneal thickness (CT). METHODS: This non-randomized, retrospective cross-sectional study included patients with senile cataract of grade 3 who underwent FLACS using the LenSx laser system. In Group 1 (32 eyes), lens fragmentation was created as a cross pattern. In Group 2 (35 eyes), lens fragmentation was created as a hybrid pattern...
November 24, 2017: Lasers in Surgery and Medicine
Ana González-Suárez, David Herranz, Enrique Berjano, Jose L Rubio-Guivernau, Eduardo Margallo-Balbás
BACKGROUND/OBJECTIVE: Radiofrequency (RF) catheter ablation is a minimally invasive medical procedure used to thermally destroy the focus of cardiac arrhythmias. Novel optical techniques are now being integrated into RF catheters in order to detect the changes in tissue properties. Loss of birefringence due to fiber denaturation at around 70°C is related to changes in accumulated phase retardation and can be measured by polarization-sensitive optical coherence reflectometry (PS-OCR)...
November 23, 2017: Lasers in Surgery and Medicine
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