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Lasers in Surgery and Medicine

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https://www.readbyqxmd.com/read/28432775/application-for-lower-facial-fat-reduction-and-tightening-by-static-type-monopolar-1-mhz-radio-frequency%C3%A2-for-body-contouring
#1
Jun Sugawara, Seiko Kou, Kenichi Kokubo, Aimi Kuroda, Yoshie Hashizume, Shinji Kobayashi, Jirou Maegawa, Toshihiko Satake
INTRODUCTION: Liposuction and mesotherapy are popular treatments for fat reduction of lower face, but because these treatments are invasive, a novel non-invasive treatment with similar or better efficacy has been sought. There are various devices such as CoolSculpt, laser, RF, and HIFU that are used as non-invasive treatments for fat reduction and body contouring, but these applications have not been applied to facial fat reduction. In this study, we selected Monopolar 1-MHz RF for body contouring to be applied for fat reduction and tightening of the lower face...
April 22, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28432681/retrospective-single-center-study-of-the-efficacy-of-large-spot-532%C3%A2-nm-laser-for-the-treatment-of-facial-capillary-malformations-in-44-patients-with-the-use-of-three-dimensional-image-analysis
#2
Bartłomiej Kwiek, Michał Rożalski, Cezary Kowalewski, Marcin Ambroziak
OBJECTIVE: We wanted to asses the efficacy of large spot 532 nm laser for the treatment of facial capillary malformations with the use of three-dimensional (3D) image analysis. STUDY DESIGN AND METHODS: Retrospective single center study on previously non-treated patients with facial capillary malformations (CM) was performed. A total of 44 consecutive Caucasian patients aged 5-66 were included. Patients had 3D photography performed before and after and had at least one single session of treatment with 532 nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser with contact cooling, fluencies ranging from 8 to 11...
April 22, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28418107/a-new-path-in-defining-light-parameters-for-hair-growth-discovery-and-modulation-of-photoreceptors-in-human-hair-follicle
#3
Serena Buscone, Andrei N Mardaryev, Bianca Raafs, Jan W Bikker, Carsten Sticht, Norbert Gretz, Nilofer Farjo, Natallia E Uzunbajakava, Natalia V Botchkareva
BACKGROUND AND OBJECTIVE: Though devices for hair growth based on low levels of light have shown encouraging results, further improvements of their efficacy is impeded by a lack of knowledge on the exact molecular targets that mediate physiological response in skin and hair follicle. The aim of this study was to investigate the expression of selected light-sensitive receptors in the human hair follicle and to study the impact of UV-free blue light on hair growth ex vivo. MATERIAL AND METHODS: The expression of Opsin receptors in human skin and hair follicles has been characterized using RT-qPCR and immunofluorescence approaches...
April 18, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28418076/ultrasonic-modulation-of-tissue-optical-properties-in-ex-vivo-porcine-skin-to-improve-transmitted-transdermal-laser-intensity
#4
Paul J D Whiteside, Chenxi Qian, Nicholas Golda, Heather K Hunt
BACKGROUND AND OBJECTIVE: Applications of light-based energy devices involving optical targets within the dermis frequently experience negative side-effects resultant from surface scattering and excess optical absorption by epidermal melanin. As a broadband optical absorber, melanin decreases the efficacy of light-based treatments throughout the ultraviolet, visible, and near-infrared spectra while also generating additional heat within the surface tissue that can lead to inflammation or tissue damage...
April 18, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28401629/a-1-470%C3%A2-nm-diode-laser-in-stapedotomy-mechanical-thermal-and-acoustic-effects
#5
Simone P C Koenraads, Tjeerd de Boorder, Wilko Grolman, Digna M A Kamalski
BACKGROUND AND OBJECTIVES: Multiple laser systems have been investigated for their use in stapes surgery in patients with otosclerosis. The diode 1,470 nm laser used in this study is an attractive laser system because it is easily transported and relatively inexpensive in use. This wavelength has relative high absorption in water. This study aimed to investigate the mechanical, thermal, and acoustic effects of the diode 1,470 nm laser on a stapes in an inner ear model. MATERIALS AND METHODS: Experiments were performed in an inner ear model including fresh frozen human stapes...
April 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28401579/mri-assessment-of-tissue-effects-after-180-w-xps-greenlight-laser-vaporization-of-the-prostate
#6
Romain Huet, Romain Mathieu, Tanguy Rohou, Benoit Peyronnet, Andrea Manunta, Gregory Verhoest, Karim Bensalah, Sebastien Vincendeau
BACKGROUND AND OBJECTIVE: Photoselective vaporization of the prostate (PVP) is an alternative to transurethral resection of the prostate (TURP) in the surgical management of Benign Prostate Obtruction (BPO), with a better hemostatic effect due to a coagulation depth of several millimeters. The objective of this study was to prospectively assess the tissue effects of PVP by Magnetic Resonance Imaging (MRI). MATERIALS AND METHODS: From December to February 2014, ten patients were included in a prospective study and underwent PVP performed by a single surgeon with the Greenlight™ laser 180-W XPS...
April 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28382712/traser-an-innovative-device-for-the-treatment-of-nasal-telangiectasias
#7
Paul M Friedman, Stanislav N Tolkachjov, Elizabeth R Geddes, Karl A Tillman, Christopher B Zachary
BACKGROUND: Destruction of blood vessels by selective photothermolysis has been successfully achieved using a number of different laser and light systems, none of which provide significant independent variation in parameters such as wavelength. OBJECTIVE: To evaluate the safety and efficacy of a novel configurable device in the treatment of nasal telangiectasias. METHODS: Fifteen subjects aged 42-73 with Fitzpatrick skin types I and II were treated for nasal telangiectasias of various sizes...
April 6, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28370223/novel-assessment-tool-based-on-laser-speckle-contrast-imaging-to-diagnose-severe-ischemia-in-the-lower-limb-for-patients-with-peripheral-arterial-disease
#8
Sotaro Katsui, Yoshinori Inoue, Kimihiro Igari, Takahiro Toyofuku, Toshifumi Kudo, Hiroyuki Uetake
OBJECTIVE: We propose a new assessment tool to diagnose severe ischemia of the lower limb in peripheral arterial disease, using laser speckle contrast imaging to evaluate heating-induced microcirculatory fluctuations in the proximal and distal sites of the dorsal foot. STUDY DESIGN: A cross-sectional study. METHODS: We recorded the slope describing the behavior of perfusion values (decrease or plateau) following the initial, heating-induced increase in perfusion in 63 feet of patients with clinical signs of peripheral arterial disease...
April 2, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28370134/red-light-photodynamic-therapy-for-actinic-keratosis-using-37%C3%A2-j-cm-2-fractionated-irradiation-with-12-3%C3%A2-mw-cm-2-after-30-minutes-incubation-time-compared-to-standard-continuous-irradiation-with-75%C3%A2-mw-cm-2-after-3-hours-incubation-time-using-a-mathematical
#9
Anne-Sophie Vignion-Dewalle, Gregory Baert, Laura Devos, Elise Thecua, Claire Vicentini, Laurent Mortier, Serge Mordon
OBJECTIVE AND STUDY DESIGN: Photodynamic therapy (PDT) is an emerging treatment modality for various diseases, especially for dermatological conditions. Although, the standard PDT protocol for the treatment of actinic keratoses in Europe has shown to be effective, treatment-associated pain is often observed in patients. Different modifications to this protocol attempted to decrease pain have been investigated. The decrease in fluence rate seems to be a promising solution. Moreover, it has been suggested that light fractionation significantly increases the efficacy of PDT...
April 2, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28370217/the-sensitivity-of-glioma-cells-to-pyropheophorbide-%C3%AE-methyl-ester-mediated-photodynamic-therapy-is-enhanced-by-inhibiting-abcg2
#10
Li Pan, Haidan Lin, Si Tian, Dingqun Bai, Yuhan Kong, Lehua Yu
BACKGROUND AND OBJECTIVE: To study the mechanisms of human glioblastoma cell resistance to methyl ester pyropheophorbide-a-mediated photodynamic therapy (MPPa-PDT) and the relationship between the cells and adenosine triphosphate-binding cassette superfamily G member 2 (ABCG2). STUDY DESIGN/MATERIALS AND METHODS: The sensitivity of four human glioma cell lines (U87, A172, SHG-44, and U251) to MPPa-PDT was detected with a CCK-8 assay. Cell apoptosis, intracellular MPPa, and singlet oxygen were tested with flow cytometry...
March 29, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28370019/efficacy-of-ultra-short-sub-30-minute-incubation-of-5-aminolevulinic-acid-photodynamic-therapy-in-vitro
#11
Eugene Koo, Evan Austin, Andrew Mamalis, Jared Jagdeo
BACKGROUND AND OBJECTIVE: The estimated incidence of cutaneous squamous cell carcinoma (SCC) is 700,000 cases per year. In the US, SCC incidence is highest among fair skinned adults older than 50 years of age. Thus, as the population ages, the reported number of SCCs will likely increase in the future. Photodynamic therapy (PDT) is an FDA approved therapy for treatment of actinic keratoses (AKs), a precursor to cutaneous SCC lesions. The FDA approved incubation time of the photosensitizing agent 5-aminolevulinic acid (ALA) is 14-18 hours...
March 29, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28333393/laser-generated-shockwaves-enhance-antibacterial-activity-against-biofilms-in-vitro
#12
William Yao, Edward C Kuan, Nathan C Francis, Maie A St John, Warren S Grundfest, Zachary D Taylor
BACKGROUND AND OBJECTIVES: Bacterial biofilm formation within chronic wound beds, which provides an effective barrier against antibiotics, is a known cause of recalcitrant infections and a significant healthcare burden, often requiring repeated surgical debridements. Laser-generated shockwaves (LGS) is a novel, minimally invasive, and nonthermal modality for biofilm mechanical debridement which utilizes compressive stress waves, generated by photonic absorption in thin titanium films to mechanically disrupt the biofilm...
March 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28333369/in-vivo-multiphoton-microscopy-of-picosecond-laser-induced-optical-breakdown-in-human-skin
#13
Mihaela Balu, Griffin Lentsch, Dorota Z Korta, Karsten König, Kristen M Kelly, Bruce J Tromberg, Christopher B Zachary
IMPORTANCE: Improvements in skin appearance resulting from treatment with fractionated picosecond-lasers have been noted, but optimizing the treatment efficacy depends on a thorough understanding of the specific skin response. The development of non-invasive laser imaging techniques in conjunction with laser therapy can potentially provide feedback for guidance and optimizing clinical outcome. OBJECTIVE: The purpose of this study was to demonstrate the capability of multiphoton microscopy (MPM), a high-resolution, label-free imaging technique, to characterize in vivo the skin response to a fractionated non-ablative picosecond-laser treatment...
March 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28319270/evaluation-of-a-transparent-perfluorodecalin-infused-patch-as-an-adjunct-to-laser-assisted-tattoo-removal-a-pivotal-trial
#14
Brian S Biesman, Cara Costner
BACKGROUND AND OBJECTIVE: Laser-assisted treatment of tattoos is well recognized to produce opaque epidermal whitening that prevents multiple sequential passes during a single treatment session. The amount of epidermal whitening produced in association with the procedure can be minimized by topical application of perfluorodecalin (PFD), which is an optical clearing agent. This pivotal trial assessed the ability of a transparent PFD-infused patch used in conjunction with a Q-switched nanosecond laser in the treatment of tattoos to permit multiple laser passes during a single 5 minute treatment session in comparison to the number of passes that could be completed using conventional treatment of the tattoo with the laser alone...
March 20, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28231400/evaluation-of-the-combined-use-of-narrow-band-imaging-and-high-speed-imaging-to-discriminate-laryngeal-lesions
#15
Veronika Volgger, Axelle Felicio, Jörg Lohscheller, Anna S Englhard, Hanan Al-Muzaini, Christian S Betz, Maria E Schuster
BACKGROUND AND OBJECTIVE: Laryngeal lesions are usually investigated by microlaryngoscopy, biopsy, and histopathology. This study aimed to evaluate the combined use of Narrow Band Imaging (NBI) and High-Speed Imaging (HSI) in the differentiation of glottic lesions in awake patients. STUDY DESIGN: Prospective diagnostic study. MATERIALS AND METHODS: Thirty-six awake patients with 41 glottic lesions were investigated with both NBI and HSI, and the suspected diagnoses were compared to the histopathological results of tissue biopsies taken during subsequent microlaryngoscopies...
February 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28231390/intraoperative-assessment-of-laryngeal-pathologies-with-optical-coherence-tomography-integrated-into-a-surgical-microscope
#16
Anna S Englhard, Tom Betz, Veronika Volgger, Eva Lankenau, Georg J Ledderose, Herbert Stepp, Christian Homann, Christian S Betz
OBJECTIVE: Endoscopic examination followed by tissue biopsy is the gold standard in the evaluation of lesions of the upper aerodigestive tract. However, it can be difficult to distinguish between healthy mucosa, dysplasia, and invasive carcinoma. Optical coherence tomography (OCT) is a non-invasive technique which acquires high-resolution, cross-sectional images of tissue in vivo. Integrated into a surgical microscope, it allows the intraoperative evaluation of lesions simultaneously with microscopic visualization...
February 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28220505/fractional-microplasma-radiofrequency-technology-for-non-hypertrophic-post-burn-scars-in-asians-a-prospective-study-of-95-patients
#17
Shen Wang, Jing Mi, Qingfeng Li, Rui Jin, Jiying Dong
BACKGROUND: Laser and other energy devices are emerging, minimally invasive treatments for scars. Among the various techniques, fractional microplasma radiofrequency technology (FMRT) has proven to be an effective treatment option for various types of scars and skin conditions such as rhytids, striae distensae, and hyperpigmentation. OBJECTIVE: This prospective clinical trial was designed to evaluate the efficacy and safety of FMRT for treating non-hypertrophic post-burn scars in the Asian population...
February 20, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28185275/surface-markers-for-guiding-cylindrical-diffuser-fiber-insertion-in-interstitial-photodynamic-therapy-of-head-and-neck-cancer
#18
Emily Oakley, David A Bellnier, Alan Hutson, Brian Wrazen, Hassan Arshad, Harry Quon, Gal Shafirstein
BACKGROUND AND OBJECTIVES: Image-based treatment planning can be used to compute the delivered light dose during interstitial photodynamic therapy (I-PDT) of locally advanced head and neck squamous cell carcinoma (LA-HNSCC). The objectives of this work were to evaluate the use of surface fiducial markers and flexible adhesive grids in guiding interstitial placement of laser fibers, and to quantify the impact of discrepancies in fiber location on the expected light dose volume histograms (DVHs)...
February 10, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28181673/laser-induced-thermal-coagulation-enhances-skin-uptake-of-topically-applied-compounds
#19
C S Haak, J Hannibal, U Paasch, R R Anderson, M Haedersdal
BACKGROUND: Ablative fractional laser (AFL) generates microchannels in skin surrounded by a zone of thermally altered tissue, termed the coagulation zone (CZ). The thickness of CZ varies according to applied wavelength and laser settings. It is well-known that AFL channels facilitate uptake of topically applied compounds, but the importance of CZ is unknown. METHODS: Franz Cells were used to investigate skin uptake and permeation of fluorescent labeled polyethylene glycols (PEGs) with mean molecular weights (MW) of 350, 1,000, and 5,000 Da...
February 9, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28411386/lars-o-svaasand
#20
Thomas E Milner
No abstract text is available yet for this article.
April 2017: Lasers in Surgery and Medicine
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