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Journal of Hospital Infection

A Semple, E O'Currain, D O'Donovan, B Hanahoe, D Keady, U Ní Riain, E Moylett
BACKGROUND: Neonatal sepsis is a leading cause of morbidity and mortality in neonatal units worldwide. Meticillin-resistant Staphylococcus aureus (MRSA) has become a leading causative pathogen. Many neonatal units experience endemic colonization and infection of their infants, which is often very challenging to successfully eradicate. AIM: To assess the impact of neonatal unit refurbishment and redesign on endemic MRSA colonization and infection. METHODS: A retrospective review was carried out over an eight-year period in a 14-cot, level 2-3 neonatal unit in University Hospital Galway, a large university teaching hospital in the West of Ireland...
September 12, 2018: Journal of Hospital Infection
G Kampf
No abstract text is available yet for this article.
September 11, 2018: Journal of Hospital Infection
Nyambura Moremi, Heike Claus, Vitus Silago, Pardon Kabage, Reuben Abednego, Mecky Matee, Ulrich Vogel, Stephen E Mshana
No abstract text is available yet for this article.
September 6, 2018: Journal of Hospital Infection
Layth Alsaffar, Lindsey Osbourne, Nathan Thomas Bourne
No abstract text is available yet for this article.
September 5, 2018: Journal of Hospital Infection
Chi Xu, Pengfei Qu, Tao Deng, Kerri Bell, Jiying Chen
AIMS: The study aimed to evaluate whether simultaneous bilateral total joint arthroplasty (SBTJA) increases deep infection risk compared to staged bilateral total joint arthroplasty (StBTJA). MATERIALS: All studies were retrieved from PubMed, EMBASE, Cochrane library databases, Web of Science, PEDro, CINAHL, SPORTDiscus and SCOPUS. A meta-analysis was conducted to compare PJI rate between SBTJA and StBTJA patients. FINDINGS: Overall, there were 16 studies with 36,765 patients who underwent SBTJA and 71,558 patients who underwent StBTJA...
September 4, 2018: Journal of Hospital Infection
Nasrinsadat Mirtalaei, Aliasghar Farazi, Mohsen Ebrahimi Monfared, Abolfazl Jokar
Ventilator-associated pneumonia (VAP) is one of the most important problems of intensive care units. 84 neurologic patients with acute stroke (Glasgow Coma Score ≤ 8) were entered into a double-blind clinical trial. Patients in the intervention group received piperacillin-tazobactam 4g/0.5g at the time of intubation and 12 hours later. The incidences of early-onset (within 4 days of intubation) and late-onset VAP were 9.2 and 26.9 episodes/1,000 days of mechanical ventilation in the intervention and control groups, repectively (OR, 0...
September 1, 2018: Journal of Hospital Infection
Fermín Acosta, Laura Pérez-Lago, María Jesús Ruiz Serrano, Mercedes Marín, Thomas A Kohl, Nuria Lozano, Stefan Niemann, Maricela Valerio, María Olmedo, María Jesús Pérez-Granda, María Rosario Pérez Pérez, Emilio Bouza, Patricia Muñoz, Darío García de Viedma
Mycobacterium chimaera is involved in a worldwide-alert owing to contaminated heater-cooler-units. We implemented an RT-PCR-based procedure to survey undetected cases of M. chimaera infection. The PCR was negative in the 59 prosthetic heart-valves from patients with PCR-16SrRNA-negative infective endocarditis. PCR identified M. chimaera in one of 15 clinically significant retrospective MAC isolates, which corresponded to a patient who had undergone heart-valve replacement in a different institution. Whole-genome-sequencing demonstrated that he was the first case in Spain with involvement of the strain responsible for the global outbreak...
September 1, 2018: Journal of Hospital Infection
Megan McHaney-Lindstrom, Courtney Hebert, Jennifer Flaherty, Julie E Mangino, Susan Moffatt-Bruce
No abstract text is available yet for this article.
August 30, 2018: Journal of Hospital Infection
Jana Prattingerová, Emmi Sarvikivi, Jukka Ollgren, Outi Lyytikäinen
No abstract text is available yet for this article.
August 29, 2018: Journal of Hospital Infection
M Gallouche, P Pavese, I Pierre, M R Mallaret, J P Stahl, C Landelle
No abstract text is available yet for this article.
August 29, 2018: Journal of Hospital Infection
Yin Mo, Isaac Low, Siok Kuan Tambyah, Paul A Tambyah
The burden of healthcare-associated infections (HAIs) has traditionally been measured using clinical and economic outcomes. We conducted semi-structured interviews with 18 patients or their caregivers affected by HAI caused by multidrug resistant organisms (MDRO) to better understand the human impact of HAI. Most patients had misconceptions about HAI and antimicrobial resistance, leading to strong negative feelings towards HAIs despite positive views of their healthcare providers. Communication issues across power imbalances need to be addressed to help deal with trauma of HAIs...
August 29, 2018: Journal of Hospital Infection
Christopher F Lowe, Victor Leung, Loretta Karakas, Linda Merrick, Tanya Lawson, Marc G Romney, Gordon Ritchie, Michael Payne
During the 2017/18 influenza season, our virology laboratory implemented the cobas® Influenza A/B & RSV (Roche Molecular Diagnostics, Pleasanton, CA) for influenza outbreak management in 2 scenarios: initial outbreak investigation or at outbreak conclusion to avoid prolonged measures. Twenty-seven investigations were conducted, including declaration of 11 influenza A/B outbreaks. 30% of investigations would have missed the standard batched daily laboratory-developed respiratory PCR, and delayed outbreak confirmation until the following day...
August 29, 2018: Journal of Hospital Infection
A Eikelenboom-Boskamp, K Saris, M van Loosbroek, M I J Drabbe, F de Jongh, J W D de Jong, P G M Boom-Poels, A Voss
Following the first point prevalence study in Dutch nursing homes conducted each November from 2007 to 2009, we conducted a follow-up point prevalence study of healthcare-associated infections (HAIs) each November from 2010 to 2017. Similar methods and criteria were used. Resident characteristics were recorded, data collection was performed by the attending elderly care physicians, via an online survey, as well as via a specifically designed App from 2012. As of the same year information on incontinence was added...
August 24, 2018: Journal of Hospital Infection
M Sansone, Å Wiman, M L Karlberg, M Brytting, L Bohlin, L-M Andersson, J Westin, R Nordén
AIM: To describe a hospital outbreak of influenza B virus (InfB) infection during season 2015/2016 by combining clinical and epidemiological data with molecular methods. METHODS: Twenty patients diagnosed with InfB from a hospital outbreak over a four-week-period were included. Nasopharyngeal samples (NPS) positive for InfB by multiplex real-time polymerase chain reaction were sent for lineage typing and whole genome sequencing (WGS). Medical records were reviewed retrospectively for data regarding patient characteristics, localization, exposure and outcome, and assembled into a timeline...
August 22, 2018: Journal of Hospital Infection
Evelyn Shaw, Aina Gomila, Marta Piriz, Rafel Perez, Jordi Cuquet, Ana Vazquez, Josep M Badia, Ana Lérida, Domenico Fraccalvieri, Anna Marron, Nuria Freixas, Antoni Castro, Antonio Cruz, Enric Limón, Francesc Gudiol, Sebastiano Biondo, Jordi Carratalà, Miquel Pujol
BACKGROUND: Accounting for time-dependency and competing events are strongly recommended to estimate excess length of stay (LOS) and risk of death associated with healthcare-associated infections. AIM: To assess the effect of organ/space (OS) surgical site infection (SSI) on excess LOS and in-hospital mortality in patients undergoing elective colorectal surgery (ECS). METHODS: A multicentre prospective adult cohort undergoing ECS, January 2012 to December 2014, at 10 Spanish hospitals was used...
August 17, 2018: Journal of Hospital Infection
K Agwuh, M Weinbren
No abstract text is available yet for this article.
August 16, 2018: Journal of Hospital Infection
G Cheminet, N Kapel, A Bleibtreu, H Sadou-Yaye, A Bellanger, X Duval, F Joly, B Fantin, V de Lastours
No abstract text is available yet for this article.
August 11, 2018: Journal of Hospital Infection
J A Brett, S A Johnson, D R M Cameron, C R Lane, M Easton, A van Diemen, B Sutton, A L Bull, M J Richards, L J Worth
Carbapenemase-producing Enterobacteriaceae (CPE) infections are increasingly reported in Australian hospitals, but prevalence is unknown. In 2016, Victorian hospitals conducted CPE point-prevalence surveys (PPS) in high-risk wards (intensive care, haematology, transplant). Forty-three hospitals performed 134 surveys, with 1839/2342 (79%) high-risk patients screened. Twenty-four surveys were also performed in other wards. Inability to obtain patient consent was the leading reason for non-participation. In high-risk wards, no CPE cases were detected; three cases were identified in other wards...
August 10, 2018: Journal of Hospital Infection
Eva M Krockow, Andrew M Colman, Edmund Chattoe-Brown, David R Jenkins, Nelun Perera, Shaheen Mehtar, Carolyn Tarrant
BACKGROUND: Antimicrobial resistance is a global health threat, partly driven by inappropriate antibiotic prescriptions for acute medical patients in hospitals. AIM: To provide a systematic review of qualitative research on antibiotic prescribing decisions in hospitals worldwide including broad-spectrum antibiotic use. METHODS: A systematic search of qualitative research on antibiotic prescribing for adult hospital patients published between 2007 and 2017 was conducted...
August 9, 2018: Journal of Hospital Infection
K Currie, C King, K McAloney-Kocaman, N J Roberts, J MacDonald, A Dickson, S Cairns, N Khanna, P Flowers, J Reilly, L Price
BACKGROUND: To reduce the risk of transmission of meticillin resistant Staphylococcus aureus (MRSA), international guidelines recommend admission screening to identify hospital patients at risk of colonisation. However, routine monitoring indicates that optimum screening compliance levels are not always achieved. In order to enhance compliance, we must better understand those factors which influence staff screening behaviours. AIM: To identify factors which influence staff compliance with hospital MRSA screening policies...
August 8, 2018: Journal of Hospital Infection
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