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Journal of Hospital Infection

Oyebola Fasugba, Jane Koerner, Noleen Bennett, Simon Burrell, Roland Laguitan, Alex Hoskins, Wendy Beckingham, Brett G Mitchell, Anne Gardner
Phase II of the Surveillance to Reduce Urinary Tract Infections project piloted a website for point prevalence surveys of healthcare-associated (HAUTI) and catheter-associated urinary tract infection in Australian hospitals and aged care homes. This study describes development and evaluation of the website for online data collection. Evaluation findings from 38 data collectors indicated most respondents found website registration and web form use easy (n=22; 58% and n=16; 43%, respectively). The need for improved computer literacy skills and automated data systems were highlighted...
January 13, 2018: Journal of Hospital Infection
Joobin Hooshmand, Penny Allen, Nima Pakrou, Brendan J Vote
No abstract text is available yet for this article.
January 12, 2018: Journal of Hospital Infection
James Gray, Beryl Oppenheim, Nikunj Mahida
No abstract text is available yet for this article.
January 12, 2018: Journal of Hospital Infection
Sara Romano-Bertrand, Marine Evrevin, Chloé Dupont, Jean-Marc Frapier, Jean-Claude Sinquet, Elodie Bousquet, Bernard Albat, Estelle Jumas-Bilak
Recently, surgical site infections due to non-tuberculous Mycobacterium (NTM) have been linked to heater-cooler units (HCUs) contamination. ECDC and manufacturers now recommend the use of hydrogen peroxide in filtered water to fill HCU tanks. After implementation of these measures in our hospital, HCUs became heavily contaminated by opportunistic waterborne pathogens such as Pseudomonas aeruginosa and Stenotrophomonas maltophilia. No NTM were detected but fast-growing resistant bacteria could impair their detection...
January 10, 2018: Journal of Hospital Infection
Yu-Mi Lee, Chisook Moon, Young Jin Kim, Hee-Joo Lee, Mi Suk Lee, Ki-Ho Park
BACKGROUND: Gram-negative bacteria are increasingly the cause of catheter-related bloodstream infections (CRBSI), which show a rapidly rising prevalence of multidrug-resistant strains. We evaluated the impact of delayed central venous catheter (CVC) removal on clinical outcomes in patients with gram-negative CRBSI. METHODS: Between January 2007 and December 2016, patients with gram-negative bacteremia and CVC placement, from two tertiary care hospitals, were retrospectively included...
January 9, 2018: Journal of Hospital Infection
Dana Danino, Rimma Melamed, Batya Sterer, Nurith Porat, Guy Hazan, Alex Gushanski, Eilon Shany, David Greenberg, Avraham Borer
BACKGROUND: Preterm infants are at high risk for extended spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) sepsis and neonatal intensive care unit (NICU) outbreaks. Maternal colonization with ESBL-E may be precursory to maternal-neonatal transmission. However, there is no consensus regarding surveillance of pregnant women for ESBL-E colonization. AIM: To identify pairs of mothers and offspring harbouring same-strain ESBL-E colonization and to determine whether maternal transmission may play a role in increasing ESBL-E carriage in preterm infants...
January 9, 2018: Journal of Hospital Infection
Samantha Hall, Bozena Poller, Claire Bailey, Samantha Gregory, Richard Clark, Paul Roberts, Anne Tunbridge, Vin Poran, Cariad Evans, Brian Crook
BACKGROUND: Variations currently exist across the UK in the choice of personal protective equipment (PPE) used by healthcare workers when caring for patients with suspected high consequence infectious diseases (HCIDs). AIM: To test the protection afforded to healthcare workers by current PPE ensembles during assessment of a suspected HCID case and to provide an evidence base to justify proposal of a unified PPE ensemble for healthcare workers across the UK. METHODS: One 'basic level' (enhanced precautions) PPE ensemble and five 'suspected case' PPE ensembles were evaluated in volunteer trials using 'Violet'; a UV-fluorescence-based simulation exercise to visualise exposure/contamination events...
January 8, 2018: Journal of Hospital Infection
Daiichi Morii, Naoki Ichinose, Takayuki Yokozawa, Toshimi Oda
OBJECTIVES: To assess the efficacy and the limitations of antifungal antimicrobial stewardship programs. METHODS: A bundle to manage infectious diseases was implemented in our hospital in October 2010. Data regarding antimicrobial use density (AUD) from April 2006 to May 2016 were collected. Trends in AUD were assessed using an interrupted time-series model for three separate periods: the pre-bundle, the bundle implementation, and the long-term follow-up periods...
January 8, 2018: Journal of Hospital Infection
Yuichi Katanami, Kayoko Hayakawa, Takeshi Shimazaki, Yuko Sugiki, Saho Takaya, Kei Yamamoto, Satoshi Kutsuna, Yasuyuki Kato, Norio Ohmagari
BACKGROUND: Contact precautions are required to prevent transmission of multidrug-resistant organisms; however, reports on adherence rates vary. Through video monitoring, we evaluated adherence to the use of personal protective equipment (PPE) among different types of healthcare workers. METHODS: This study was an observational study conducted in a 781-bed tertiary hospital from July 2016 to March 2017. We installed cameras in areas where staff don PPE. Infection control teams observed the videos and assessed adherence rates...
January 6, 2018: Journal of Hospital Infection
T Akhtar, J Cargill, C Gerrard, F Shaw, N A Cunliffe, R P D Cooke, B Pizer
We reviewed seven year's data to examine stool testing for rotavirus in patents treated on a regional Paediatric Oncology Unit before and after the introduction of UK-wide rotavirus immunisation in July 2013. The prevalence of rotavirus positivity has diminished since the introduction of rotavirus immunisation, with 21 of 416 positive samples between 2010 and 2012, but only one positive test out of 122 samples in 2015 and 2016. Based on these results, we suggest there is very little utility for routine rotavirus testing in children and young people with cancer presenting with diarrhoea...
January 5, 2018: Journal of Hospital Infection
Weinbren Mj, Collins M, Heathcote R, Umar M, Nisar M, Ainger C, Masters P
Laboratory processing of blood cultures has remained static over the past 30 years despite increasing antibiotic resistance and advances in analyser design. By siting our blood culture analyser in the Blood Sciences laboratory and optimizing the pre-analytical and analytic phases of blood culture management we reduced the time taken to detect most blood culture isolates to <12 hours. 50% of positive blood cultures containing Escherichia coli were definitively reported with antibiotic susceptibilities in <24 hours...
January 5, 2018: Journal of Hospital Infection
Selina Reay, Philip Milner, James Gray
No abstract text is available yet for this article.
December 29, 2017: Journal of Hospital Infection
Francesco Di Ruscio, Jørgen Vildershøj Bjørnholt, Kjersti Wik Larssen, Truls Michael Leegaard, Aina E F Moen, Birgitte Freiesleben de Blasio
BACKGROUND: There has been a marked increase in the incidence of MRSA during the past decade in Norway, a country with one of the lowest prevalence's and an active "search-and-destroy" policy applied to hospital settings. AIM: To characterize the trends of notification rates of community associated (CA) and healthcare associated (HA) MRSA in Norway and explore the diversity and circulation of MRSA spa-types within and outside healthcare settings. METHODS: We conducted a registry-based study on notified MRSA infections and colonizations in Norway between 2006 and 2015...
December 27, 2017: Journal of Hospital Infection
Aina Gomila, Jordi Carratalà, Sebastiano Biondo, Josep MaBadia, Doménico Fraccalvieri, Evelyn Shaw, Vicens Diaz-Brito, Lurdes Pagespetit, Núria Freixas, Montserrat Brugués, Laura Mora, Rafel Perez, Camilo Sanz, Nares Arroyo, Simona Iftimie, Enric Limón, Francesc Gudiol, Miquel Pujol
BACKGROUND: Surgical site infections (SSI) are the leading cause of healthcare-associated infections in acute care hospitals in Europe. However, the risk factors for the development of early- (EO) and late-onset (LO) SSI have not been elucidated. AIM: This study investigated the predictive factors for EO-SSI and LO-SSI in a large cohort of patients undergoing colorectal surgery. METHODS: We prospectively followed-up adult patients undergoing elective colorectal surgery in 10 hospitals (2011-2014)...
December 27, 2017: Journal of Hospital Infection
Barbara Payne, Hans-Peter Simmen, Esther Csuka, Matthias Hintzpeter, Steffen Pahl, Florian H H Brill
Prevention of wound infections is a challenge in clinical practice. The aim of this study was to assess the efficacy of polihexanide 0.04 % on acute traumatic wounds. It was a randomised, double-blind, placebo-controlled prospective trial which included 61 patients. The polihexanide group showed a significant decrease in log10 CFU (p<0.001) after 60 min treatment in comparison to baseline CFU, whereas the Ringer's solution group did not show a significant change of CFU during 60 min treatment. Treatment of polihexanide 0...
December 27, 2017: Journal of Hospital Infection
Ian Blenkharn
No abstract text is available yet for this article.
December 27, 2017: Journal of Hospital Infection
Yunbei Rao, Zhuxiao Ren, Junjuan Zhong, Xiuming Zhong, Bei Cao, Dongmei Chen, Xinnian Pan, Yanping Jia, Pingming Gao, Bingyan Yang, Qiao Zhong, Jie Yang
This multi-centre retrospective study was designed to investigate the risk factors for infection with imipenem-resistant Pseudomonas aeruginosa (IRPA) in Neonatal Intensive Care Units (NICU) in south China. All patients with confirmed P. aeruginosa infection from 8 NICU in south China were divided into two groups: imipenem-susceptible P. aeruginosa (ISPA) and IRPA. Chi-square test and logistic regression model were performed for statistical analyses. A total of 188 medical records were reviewed. In multivariate logistic analysis, imipenem treatment within two weeks of isolation of PA was the only independent risk factor (OR=6...
December 20, 2017: Journal of Hospital Infection
Reid Nakagawa, Rupali Jain, Andrew B Bryan, Jeannie D Chan
Rapid molecular blood culture Gram-positive (BC-GP) assay can promptly identify vancomycin-resistant enterococcal (VRE) bloodstream infections (BSI). We sought to evaluate patients with VRE BSI following the pre- (n=44) and post-implementation (n=20) of Verigene BC-GP assay. The average time to detection of VRE and was 25.9 + 4.1 hours (95% CI: 17.6 to 34.1 hours, p<0.001) earlier with Verigene BC-GP assay. Compared to patients in the pre-Verigene BC-GP period, the mean adjusted difference in time to administration of anti-VRE therapy was 18...
December 16, 2017: Journal of Hospital Infection
Minoru Ohno, Yosuke Shimada, Masaya Satoh, Yutaka Kojima, Kazuhiro Sakamoto, Satoshi Hori
BACKGROUND: Several reports have been published regarding cost increases attributable to surgical site infections (SSIs) in Europe and the United States. However, such studies have been limited in Japan. AIM: To evaluate the economic burden of colorectal surgical site infections on hospitals in Japan. METHODS: This study was carried out at Japanese university hospital. Amongst 265 patients who had undergone colorectal surgeries in the Department of Coloproctological Surgery between November 2014 and March 2016, 16 patients who developed SSIs and could be allocated a Diagnosis Procedure Combination (DPC) code were selected as SSI cases...
December 16, 2017: Journal of Hospital Infection
Siba Prosad Paul, Edward Michael Caplan, Hannah Alexandra Morgan, Paul Christopher Turner
The National Institute for Health and Care Excellence published guidelines for managing early-onset neonatal infections in 2012. It recommended provision for reporting blood cultures (BC) with growth detected or not detected at 36-hours. To determine if this was followed, we conducted a telephone survey amongst lead biomedical scientists based at microbiology laboratories (N=209) in the United Kingdom. 202/209 responded and 139/202 had on-site facilities for BCs. BC results with growth detected or not detected at 36-hours were available out-of-hours in 36/139 (26...
December 16, 2017: Journal of Hospital Infection
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