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Journal of Hospital Infection

Aliana Meneses Ferreira, Frederico Moreira, Thais Guimaraes, Fernanda Spadão, Jessica Fernandes Ramos, Marjorie Vieira Batista, Jayr Schmidt Filho, Silvia Figueiredo Costa, Vanderson Rocha
BACKGROUND: Bloodstream infections (BSI) are a major complication in the early phase of a hematopoietic stem cell transplant (HSCT). AIM: To describe the incidence and risk factors for BSI occurring in the pre-engraftment phase of HSCT and its impact on mortality. METHODS: We retrospectively analysed clinical variables of 232 HSCT patients between 2014 and 2015. Univariate Cox regression analyses were performed to test the association between each covariate and the outcome...
March 9, 2018: Journal of Hospital Infection
Andrew Smith, Sandra Winter, David Lappin, Andrea Sherriff, Ian McIvor, Pamela Philp, Nigel Suttner, Sulisti Holmes, Alan Stewart
BACKGROUND: Currently UK vCJD cases total 178, with an estimated maximum 1:2,000 carriage rate based on archived appendix and tonsil tissue, implying infection maybe rare but carriage relatively common. Previous workers have identified that maintenance of surgical instruments in a humid atmosphere after use and prior to cleaning assists cleaning efficacy. Relatively recently the Department of Health/Advisory Committee on Dangerous Pathogens UK have recommended a surgical instrument cleanliness threshold post cleaning of <5μg protein per instrument side...
March 9, 2018: Journal of Hospital Infection
Caroline M Coope, Neville Q Verlander, Annegret Schneider, Susan Hopkins, William Welfare, Alan P Johnson, Bharat Patel, Isabel Oliver
BACKGROUND: Following hospital outbreaks of carbapenemase-producing Enterobacteriaceae (CPE), Public Health England published a toolkit in December 2013 to promote the early detection, management and control of CPE colonisation and infection in acute hospital settings. AIM: This evaluation aimed to examine awareness, uptake, implementation and usefulness of the CPE toolkit and identify potential barriers and facilitators to its adoption in order to inform future guidance...
March 9, 2018: Journal of Hospital Infection
E Tartari, D Pires, D Pittet
No abstract text is available yet for this article.
March 9, 2018: Journal of Hospital Infection
Iolanda Alves Braga, Paola Amaral de Campos, Paulo Pinto Gontijo Filho, Rosineide Marques Ribas
BACKGROUND: Healthcare-associated infection (HAI) represents a major problem for patient safety worldwide. AIM: To provide an up-to-date picture of the extent, aetiology, risk factors and patterns of infections in intensive care units (ICUs) in 28 Brazilian hospitals of different sizes. METHODS: A one-day point prevalence survey in 2016 enrolled the ICU of hospitals from the 12 meso regions located in the State of Minas Gerais, Southeast region of Brazil...
March 6, 2018: Journal of Hospital Infection
O Smibert, A K Aung, E Woolnough, G P Carter, M B Schultz, B P Howden, T Seemann, D Spelman, S McGloughlin, A Y Peleg
Few studies have utilized molecular epidemiological methods to study transmission links to clinical isolates in intensive care units. 94 multi-drug resistant organisms (MDRO) cultured from routine specimens from ICU patients over 13 weeks were stored (11 MRSA, 2 VRE and 81 Gram-negative bacteria). Medical staff personal mobile phones, departmental phones and ICU keyboards were swabbed and cultured for MDRO; MRSA was isolated from two phones. Environmental and patient isolates of the same genus were selected for whole genome sequencing...
March 1, 2018: Journal of Hospital Infection
Frederic S Zimmerman, Marc V Assous, Amos M Yinnon, Yonit Wiener-Well
No abstract text is available yet for this article.
February 27, 2018: Journal of Hospital Infection
C P Dunne, L Kingston, B Slevin, N H O'Connell
No abstract text is available yet for this article.
February 24, 2018: Journal of Hospital Infection
Y Ortiz-Martínez, C Galindo-Regino, F Valdes-Villegas, K Mendoza-Borja, M R González-Hurtado, V Chávez-Verbel
No abstract text is available yet for this article.
February 23, 2018: Journal of Hospital Infection
Rucira Ooi, Anthony Griffiths
No abstract text is available yet for this article.
February 23, 2018: Journal of Hospital Infection
Aurélien Dinh, Hafedh Fessi, Clara Duran, Rui Batista, Hugues Michelon, Frédérique Bouchand, Raphaël Lepeule, Daniel Vittecoq, Lelia Escaut, Iradj Sobhani, Christine Lawrence, François Chast, Pierre Ronco, Benjamin Davido
BACKGROUND: Carbapenem-resistant Enterobacteriaceae (CRE) and Vancomycin-resistant enterococci (VRE) carriage is increasing worldwide. Fecal microbiota transplantation (FMT) appears to be an attractive option for decolonization. We aimed to evaluate CRE versus VRE clearance by FMT among carriers. METHODS: We performed a multicentre trial on patients with CRE or VRE digestive tract colonization who received FMT between January 2015 and April 2017. Adult patients with CRE or VRE colonization were included; confirmed by three consecutive rectal swabs at weekly intervals, including one in the week prior to FMT...
February 22, 2018: Journal of Hospital Infection
Joo-Hee Hwang, Jeong Su Park, Eunyoung Lee, Ji Yun Bae, Kyoung-Ho Song, Pyoeng Gyun Choe, Wan Beom Park, Ji Hwan Bang, Eu Suk Kim, Sang Won Park, Nam Joong Kim, Myoung-Don Oh, Hong Bin Kim
A 10-month active surveillance study was conducted to assess carriage of carbapenemase-producing Enterobacteriaceae (CPE), vancomycin-resistant enterococci (VRE) and toxigenic Clostridium difficile colonization among patients transferred to hospital from long-term care facilities (LTCFs). Four (1.4%) carbapenem-resistant Enterobacteriaceae (none CPE), 59 (21%) VRE carriers, and 20 (7.1%) persons colonized with toxigenic C. difficile were identified from 282 rectal specimens. There was no outbreak of VRE infection during the study period...
February 21, 2018: Journal of Hospital Infection
F N J Frakking, W S Bril, J C Sinnige, J E van 't Klooster, B A W de Jong, E J van Hannen, M Tersmette
BACKGROUND: A large outbreak of three epidemic vancomycin-resistant Enterococcus faecium (VRE) clones affected our hospital for almost two years. AIM: To describe the strategy to successfully control this outbreak and eradicate VRE from our hospital. METHODS: Infection control interventions started after detection of VRE in three patients. After ongoing transmission despite isolation precautions, cleaning and contact tracing, hospital-wide surveillance was started...
February 20, 2018: Journal of Hospital Infection
Yhu-Chering Huang, Chih-Jung Chen, Ching-Chia Kuo, Min-Chi Lu
We identified 27 (0.51%) USA300 isolates from a pool of 5308 meticillin-resistant Staphylococcus aureus (MRSA) isolates collected in Taiwan between 1995 and October 2015, including 12 infecting isolates from 10 patients. The first two isolates were identified in 2005 and 23 isolates since 2010. Phylogenetic analysis revealed all the local isolates were closely related to those in North America and there was a clade consisting of 13 local isolates from 10 patients. MRSA USA300 existed in Taiwan in 2005 or earlier, with increasing identification since 2010...
February 20, 2018: Journal of Hospital Infection
Carlos Rodríguez-Lucas, Javier Fernández, José Antonio Boga, Lucia López-Amor, Lorena Forcelledo, Eva Lázaro-López, M Rosario Rodicio
BACKGROUND: Post-neurosurgical ventriculitis is mainly caused by coagulase-negative staphylococci. The rate of linezolid resistant S. epidermidis (LRSE) is increasing worldwide. AIMS: To report clinical and microbiological data from a series of ventriculitis cases caused by LRSE in a Spanish hospital between 2013 and 2016. METHODS: LRSE ventriculitis cases were retrospectively reviewed in a Spanish hospital during a four-year period. Clinical/epidemiological data of the infected patients were reviewed, the isolates involved were typed by PFGE and MLST, and the molecular basis of linezolid resistance was determined...
February 16, 2018: Journal of Hospital Infection
T Heister, M Wolkewitz, K Kaier
No abstract text is available yet for this article.
February 16, 2018: Journal of Hospital Infection
M C S de Almeida, E A S Medeiros, F Agena, C C Oliveira, M V Y Swawamura, S F Costa, M J C Carmona, L M de Sa Malbouisson
No abstract text is available yet for this article.
February 16, 2018: Journal of Hospital Infection
Adel M Nada, Reham A Mohsen, Yosra M Hassan, Amira Sabry, Noha S Soliman
BACKGROUND: Maternal rectal enemas may reduce neonatal bacterial exposure during labour; this may reduce the risk of neonatal colonization with Clostridium difficile. The aim of this study was to determine the effectiveness of a saline enema during the first stage of labour in reducing neonatal colonization with C. difficile. METHODS: The study was conducted in Cairo University Hospital from January 2016 to July 2016. Asymptomatic mothers with uncomplicated vaginal delivery and their neonates without diarrhea were included...
February 13, 2018: Journal of Hospital Infection
K Nakamura, K Saito, J Kashiwazaki, T Aoyagi, K Arai, Y Hara, S Kobari, H Mori, K Ohashi, Y Takano, M Kaku, K Kanemitsu
We evaluated the bacterial removal effects of hand washing with ozonated water using the ASTM E1174 standard test method. Thirty healthy volunteers were assigned randomly to three groups: ozonated water, antimicrobial soap and water, and non-antimicrobial soap and water. A 3 log 10 CFU reduction was achieved by washing hands with ozonated water or antimicrobial soap and water. However, ozonated water was not significantly superior to non-antimicrobial soap and water. Ozonated water may remove bacteria from the hands to at least a similar extent as that by non-antimicrobial soap and water in the absence of visible dirt or body fluid contamination...
February 13, 2018: Journal of Hospital Infection
Michael G Schmidt, Cassandra D Salgado, Katherine D Freeman, Joseph F John, Robert J Cantey, Peter A Sharpe, Harold T Michels
No abstract text is available yet for this article.
February 12, 2018: Journal of Hospital Infection
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