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Journal of Hospital Infection

Emily Jane Goldstein, Rory N Gunson
No abstract text is available yet for this article.
November 5, 2018: Journal of Hospital Infection
Sabine Messler, Ingo Klare, Frank Wappler, Guido Werner, Uwe Ligges, Samir G Sakka, Frauke Mattner
BACKGROUND: Vancomycin-resistant Enterococcus faecium (VRE) is emerging in German intensive care units (ICUs). On a 32 bed surgical ICU at a university hospital increasing numbers of nosocomial cases occurred despite enforcement of hand hygiene and environmental disinfection. AIM: Introduction of universal octenidine-based bathing in order to reduce the burden of VRE. METHODS: Between 1/2012 and 3/2014 patients were screened for VRE on admission and twice weekly...
November 5, 2018: Journal of Hospital Infection
Oliver Blandy, Kate Honeyford, Myriam Gharbi, Anthony Thomas, Farzan Ramzan, Matthew J Ellington, Russell Hope, Alison Holmes, Alan P Johnson, Paul Aylin, Neil Woodford, Shiranee Sriskandan
BACKGROUND: The incidence of Escherichia coli bacteraemia in England is increasing amid concern regarding the roles of antimicrobial resistance and nosocomial acquisition on burden of disease. METHODS: Patient demographics, co-morbidity, deprivation, and mortality data together with antimicrobial susceptibility data were collected for all cases of E. coli bacteraemia between 2011 and 2015 presenting in West London. Multivariable logistic regression was used to determine the association between the category of infection (hospital or community-onset) and length of stay, ICU admission, and 30-day all-cause mortality...
November 4, 2018: Journal of Hospital Infection
M Pirš, T Cerar Kišek, V Križan Hergouth, K Seme, M Mueller Premru, S Jeverica, M Logar, T Mrvič, B Žnidaršič, O Jordan Markočič, T Lejko Zupanc
BACKGROUND: Carbapenemase-producing Enterobacteriaceae (CPE) occur only sporadically in Slovenia. AIM: To describe the first Slovenian carbapenemase-producing (CP) Klebsiella pneumoniae and Escherichia coli outbreak which occurred at the tertiary teaching hospital University Medical Centre Ljubljana from October 2014 to April 2015. METHODS: A CPE-positive case was defined as any patient infected or colonized with CPE. A strict definition of a contact patient was adopted...
November 3, 2018: Journal of Hospital Infection
Jaime Ruiz-Tovar, Carolina Llavero, Mercedes Perez-Lopez, Andres Garcia-Marin
INTRODUCTION: The aim of this study was to evaluate the effect on incisional surgical site infection (SSI) of conventional wound dressing vs vitamin E-silicone dressing in patients undergoing elective colorectal laparoscopic surgery. PATIENTS AND METHODS: A prospective, randomized study was performed. Patients were randomly assigned into 2 groups: those patients undergoing a vitamin E-silicone containing dressing (E-Sil) and those using a conventional dressing (CD)...
November 2, 2018: Journal of Hospital Infection
C Legeay, R Hue, C Berton, H Cormier, R Chenouard, S Corvec, G Birgand
Three outbreaks of carbapenemase-producing Enterobacteriaceae (CPE) in three nursing homes in western France were retrospectively assessed. In all, ten cases of colonization or infection with CPE were detected upon admission in neighbouring hospitals. Antibiotic consumption or high frailty was infrequent among them. Nursing homes should be included in a regional strategy to limit CPE spread.
October 30, 2018: Journal of Hospital Infection
Durdana Chowdhury, Arifur Rahman, Honghua Hu, Slade O Jensen, Anand Kumar Deva, Karen Vickery
BACKGROUND: Biofilms that develop on dry surfaces in the healthcare environment have increased tolerance to disinfectants. We compared the activity of formulated oxidizing disinfectants versus products containing only active ingredients against Staphylococcus aureus dry surface biofilm (DSB). METHODS: DSB was grown in the CDC bioreactor with alternating cycles of hydration and dehydration. Disinfectant efficacy was tested before and after treatment with neutral detergent for 30 seconds and in the presence or absence of standardized soil...
October 26, 2018: Journal of Hospital Infection
A A L Traversari, S P M Stefan van Heumen, A W J Arjan Hoksbergen
BACKGROUND: Large imaging systems in hybrid operating rooms are increasingly utilised. However, the effect of these ceiling mounted imaging systems on the air quality during ongoing surgical procedures has not yet been studied. The aim of this study is to evaluate the level of CFU/m3 near the surgical wound and near the instrument table during surgery. METHODS: Measurements were performed in 4 hybrid operating rooms at 4 different hospitals. During surgical procedures, at least 3 samples were taken with active slit air samplers...
October 23, 2018: Journal of Hospital Infection
C P Dunne, B L Slevin, P Treacy, N H O'Connell
No abstract text is available yet for this article.
October 22, 2018: Journal of Hospital Infection
Yi-Le Wu, Xi-Yao Yang, Xiu-Xiu Ding, Ruo-Jie Li, Meng-Shu Pan, Xue Zhao, Xiao-Qian Hu, Jing-Jing Zhang, Li-Qi Yang
BACKGROUND: The survival of pathogenic organisms in the healthcare environment plays a major role in acquiring healthcare-associated infections (HAIs). AIM: This meta-analysis was conducted to investigate whether pathogenic organisms can be transmitted from roommates and prior room occupants to other inpatients and thus increase the risk of HAIs. METHODS: We searched PubMed (from January 1966) and Embase (from January 1974) to identify studies up to March 2018...
October 22, 2018: Journal of Hospital Infection
Fenella D Halstead, Anuradha Ravi, Nicholas Thomson, Mohamed Nuur, Kathleen Hughes, Mandy Brailey, Beryl A Oppenheim
BACKGROUND: Estimates of the prevalence of asymptomatically carried C. difficile in elderly patients in long-term care ranges from 0-51%. Asymptomatic carriage is possibly a risk-factor for the development of infection, and there is ongoing debate surrounding the role of asymptomatic carriage in transmission. AIM: To investigate the prevalence of asymptomatic carriage amongst patients residing in intermediate care (bedded) facilities (ICBF), and to investigate whether asymptomatically carried C...
October 22, 2018: Journal of Hospital Infection
K M Munoz-Gutierrez, R A Canales, K A Reynolds, M P Verhougstraete
BACKGROUND: Evidence suggests that doffing and possibly disposal of used personal protective equipment (PPE) can lead to environmental contamination. AIM: To ascertain the potential for site and floor contamination when medical gloves are inappropriately disposed. METHODS: Fifteen healthcare workers (HCWs) disposed of gloves inoculated with bacteriophage and a chemical dye into a wastebasket, located 1.22 m away. Following each trial, designated sample areas were visually inspected with a blacklight for fluorescent dye stains and swabbed with a 3M Letheen Broth sponge to quantify the bacteriophage...
October 22, 2018: Journal of Hospital Infection
L F Jones, J Meyrick, J Bath, O Dunham, C A M McNulty
BACKGROUND: Escherichia coli bacteraemia rates in the UK have risen; rates are highest amongst older adults. Previous Urinary Tract Infections (UTIs) and catheterisation are risk factors. This review examines effectiveness of behavioural interventions to reduce E.coli bacteraemia and/or symptomatic UTIs for older adults. METHOD: Sixteen databases, grey literature and reference lists were searched. Titles and/or abstracts were scanned and selected papers read fully to confirm suitability...
October 22, 2018: Journal of Hospital Infection
K Bundgaard Et Al, K Bundgaard, E E Sorensen, K Ripadal, A-E Christensen, H C Schønheyder
BACKGROUND: At present, reprocessing of sterilizable medical equipment is recommended to be initiated within 6 h after completion of surgery, to ensure that the quality of the instruments does not deteriorate. A literature search showed a lack of evidence for consequences that may occur if medical personnel deviate from the standard 6 h sterilization protocol. AIM: To evaluate the 6 h recommendation for reprocessing sterilizable medical equipment by determining whether residual protein increased proportional to holding time before reprocessing was initiated, and likewise whether an increase in corrosion was present on surgical scissors proportional to holding time...
October 16, 2018: Journal of Hospital Infection
C C H Leung, G M Joynt, C D Gomersall, W T Wong, A Lee, L Ling, P K S Chan, P C W Lui, P C Y Tsoi, C M Ling, M Hui
Whereas high-flow nasal cannula use is gaining prevalence, its high gas flow raises concerns about aerosolization of infectious particles and spread of infection. This randomized controlled crossover non-inferiority trial (N = 20) evaluated the degree of environmental contamination by viable bacteria associated with the use of high-flow nasal cannula compared with conventional oxygen mask for critically ill patients with Gram-negative pneumonia. The results show that high-flow nasal cannula use was not associated with increased air or contact surface contamination by either Gram-negative bacteria or total bacteria, suggesting that additional infection control measures are not required...
October 15, 2018: Journal of Hospital Infection
M Mostafazadeh-Bora
No abstract text is available yet for this article.
October 15, 2018: Journal of Hospital Infection
M Hamid Bashir, Angela Hollingsworth, Deb Schwab, Kimberly S Prinsen, Joan E Paulson, Dan J Morse, Stéphanie F Bernatchez
BACKGROUND: Skin antisepsis is performed before surgery to minimize the risk of surgical site infections. Chlorhexidine gluconate (CHG) is routinely used in this application, but it may be removed during surgery when prepped areas are exposed to fluid and repeated blotting. AIM: This work evaluated the effect of adding a film-forming acrylate copolymer to a CHG-containing skin prep on minimizing CHG loss during a simulated surgical irrigation and wiping procedure...
October 15, 2018: Journal of Hospital Infection
A Tsutsui, K Yahara, A Clark, K Fujimoto, S Kawakami, H Chikumi, M Iguchi, T Yagi, M A Baker, T O'Brien, J Stelling
BACKGROUND: Hospital outbreaks of antimicrobial-resistant (AMR) bacteria should be detected and controlled as early as possible. AIM: To develop a framework for automatic detection of AMR outbreaks in hospitals. METHODS: Japan Nosocomial Infections Surveillance (JANIS) is one of the largest national AMR surveillance systems in the world. For this study, all bacterial data in the JANIS database were extracted between 2011 and 2016. WHONET, a free software for the management of microbiology data, and SaTScan, a free cluster detection tool embedded in WHONET, were used to analyse 2015-2016 data of eligible hospitals...
October 12, 2018: Journal of Hospital Infection
Shelanah A Fernando, Thuy Phan, Christine Parker, Tina Cai, Thomas Gottlieb
Wet surface biofilms are a potential reservoir for multidrug-resistant Gram-negative organisms, including carbapenamase-producing Enterobacteriaceae (CPE). Recognition of environmental sources is important in reducing secondary patient transmission. We report the increased detection of bla-IMP-4+ CPE in environmental samples from floor drains in Burns Unit shower rooms, when collected following cleaning as compared to pre-cleaning. We propose that disruption of biofilms during cleaning may account for the increased detection of multi-resistant organisms...
October 12, 2018: Journal of Hospital Infection
C P Dunne, N H O'Connell, B O'Brien
No abstract text is available yet for this article.
October 12, 2018: Journal of Hospital Infection
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