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Journal of Hospital Infection

Fatima Sana, Luqman Satti, Gohar Zaman, Adeel Gardezi, Anum Imtiaz, Abeera Ahmed, Muhammad Tahir Khadim
No abstract text is available yet for this article.
November 8, 2017: Journal of Hospital Infection
Christina A Fleming, Mariya Kuteva, Karen O'Hanlon, Gavin O'Brien, Gerald McGreal
BACKGROUND: Approximately 19% of morbidity in peripheral vascular surgery is attributable to wound complications, which can result in delayed healing, but also arterial or graft infection leading to limb loss and even mortality in extreme cases. AIM: To determine whether groin wound complications were reduced following the routine introduction of PICO negative pressure wound therapy dressings (Smith & Nephew, Hull, England) in patients who had peripheral vascular surgery...
November 8, 2017: Journal of Hospital Infection
Patrick Saliba, Ana Hornero, Guillermo Cuervo, Immaculada Grau, Emilio Jimenez, Dolors García, Fe Tubau, Jose María Martínez-Sánchez, Jordi Carratalà, Miquel Pujol
BACKGROUND: Vascular catheter-related bloodstream infections (CRBSIs) are highly preventable hospital-acquired infections and a major threat to patient safety. While there is significant information regarding CRBSI outcome among Intensive Care Unit (ICU) patients, data regarding non-ICU patients are scarce. AIM: To determine the risk factors associated with 30-day mortality among non-ICU patients with nosocomial CRBSIs. METHODS: Prospective cohort study of non-ICU patients with nosocomial CRBSIs in a tertiary-care centre, between January 2004 and December 2014...
November 8, 2017: Journal of Hospital Infection
Florence Skyum, Vibeke Andersen, Ming Chen, Court Pedersen, Christian Backer Mogensen
BACKGROUND: Acute infectious gastroenteritis requires contact precautions to prevent spreading. On acute admission the cause of diarrhoea is unknown, so the decision of whom to isolate has to be made on clinical information with a risk of inexpedient use of contact precautions. AIM: The aims of the study were to investigate how often gastroenteritis occurs, and thus the isolation indication has to be assessed, in Danish emergency departments, and how often patients have to remain on contact precaution according to the results of the faecal samples...
November 8, 2017: Journal of Hospital Infection
Mark I Garvey, Craig Bradley, Martin Biggs, Elisabeth Holden, Martin J Gill
No abstract text is available yet for this article.
November 7, 2017: Journal of Hospital Infection
Evelyn Shaw, Laura Gavaldà, Jordi Càmara, Rosa Gasull, Santiago Gallego, Fe Tubau, Rosa Maria Granada, Pilar Ciercoles, M Angeles Dominguez, Rafael Mañez, Jordi Carratalà, Miquel Pujol
BACKGROUND: Contaminated handwashing sinks have been identified as reservoirs that can facilitate colonisation/infection of patients with multidrug-resistant (MDR) gram-negative bacteria (GNB) in intensive care units (ICUs). To eliminate endemic MDR-GNB in our ICU, we implemented a water-safe policy that involved the removal of all sinks from patients' rooms. AIM: We aimed to assess the impact of removing patients' sinks and implementing other water-safe strategies on the annual rates of ICU-acquired MDR-GNB...
November 2, 2017: Journal of Hospital Infection
Lili Jiang, Isabel Ng Hui Leng, Yan'an Hou, Li Dunli, Linda Tan Wei Lin, Hanley Ho Jian An, Mark I-Cheng Chen
OBJECTIVE: To investigate healthcare workers (HCWs) contacts during a work day and compare these against working adults from the general population. DESIGN: Prospective survey of contacts through 24 hours self-reported diary. SETTING: Three public sector tertiary care hospitals and community-based working adults in Singapore. PARTICIPANTS: HCWs and working adults from the community. RESULTS: 211 HCWs and 1028 working adults reported a total of 4066 and 9206 contacts...
October 30, 2017: Journal of Hospital Infection
Rafael Herruzo, Maria Jose Vizcaino, Rubén Yela
INTRODUCTION: Surgical use of 4% chlorhexidine soap (CHX-4) and 10% iodine povidone (PVP-I-10) do not meet the standards defined by EN12791. We investigated whether it would be possible to use these antiseptics to increase their immediate and residual effects? METHODS: During 3 consecutive weeks, n-propanol, standard CHX-4 or PVP-I-10 were tested in two experimental groups of volunteers. The new method of applying the antiseptic substances consisted of, before donning gloves, applying (after the standard hand rub and rinse of the CHX-4 or PVP-I-10) an aqueous solution based on 5% chlorhexidine or PVP-I-10, respectively, with no further rinsing of the hands...
October 28, 2017: Journal of Hospital Infection
Yong Kyun Kim, Sae Am Song, Jeong Nyeo Lee, Minkyung Oh, Kyeong Min Jo, Hyo-Jung Kim, Jae Ha Lee, Jin-Han Park, Hang-Jea Jang, Hyeon-Kuk Kim, Sungmin Kiem
BACKGROUND: Information on the natural duration of carbapenem-resistant Enterobacteriaceae (CRE) carriage and factors associated with persistence of carriage is limited. AIM: To evaluate the clinical variables associated with persistent carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing CRE. METHODS: We retrospectively reviewed data for patients admitted between June 2015 and December 2016 who were identified as KPC-producing CRE carriers by either rectal swabs or clinical cultures...
October 27, 2017: Journal of Hospital Infection
Meghan T Murray, Candace L Johnson, Bevin Cohen, Olivia Jackson, Laney K Jones, Lisa Saiman, Elaine L Larson, Natalie Neu
BACKGROUND: Adult long term care (LTC) have high rates of antibiotic use, raising concerns about antimicrobial resistance. Few studies have examined antibiotic use in paediatric LTC. AIM: We sought to describe antibiotic use in three paediatric LTC facilities and to describe the factors associated with use. METHODS: A retrospective cohort study was conducted September 2012 - December 2015 in three paediatric LTC facilities. Medical records were reviewed for demographics, healthcare-associated infections (HAI), antimicrobial use, and diagnostic testing...
October 27, 2017: Journal of Hospital Infection
Wirlaine Glauce Maciel, Kesia Esther da Silva, Julio Croda, Rodrigo Cayô, Ana Carolina Ramos, Romário Oliveira de Sales, Gleyce Hellen de Almeida de Souza, José Victor Bortolotto Bampi, Leticia Cristina Limiere, Junior César Casagrande, Ana Cristina Gales, Simone Simionatto
Acinetobacter baumannii has been frequently associated with colonization and/or infection in neonatal intensive care units (NICU). In this study, we describe a clonal spread of carbapenem-resistant A. baumannii (CRAB) isolates in a NICU. A total of 21 CRAB isolates were collected from premature newborns. Only polymyxin B was active against such isolates. Nineteen CRAB isolates were clonally related (cluster C that belonged to worldwide-disseminated ST1). All newborns had peripheral access and previously received β-lactams therapy...
October 26, 2017: Journal of Hospital Infection
Toney Thomas Poovelikunnel, Georgina Gethin, Damodar Solanki, Elaine McFadden, Mary Codd, Hilary Humphreys
AIM: To describe the learning experience from a randomised controlled trial (RCT) comparing the efficacy of medical-grade honey (MGH) with mupirocin 2% for the eradication of nasal methicillin-resistant Staphylococcus aureus (MRSA). METHODS: Patients colonised in the nose with MRSA and age ≥18 years were recruited. Participants received either one or two courses of MGH or mupirocin 2%, three times per day for five consecutive days. RESULTS: The proportion of patients who were decolonised after one or two courses of treatment was not significantly different between MGH (18/42; 42...
October 26, 2017: Journal of Hospital Infection
Steven Caskey, Jonathan Stirling, John E Moore, Jacqueline C Rendall
No abstract text is available yet for this article.
October 26, 2017: Journal of Hospital Infection
Wouter van den Bijllaardt, Marco M Janssens, Anton G Buiting, Anouk E Muller, Johan W Mouton, Jaco J Verweij
BACKGROUND: ESBL screening and contact precautions on patients at high risk for ESBL carriage are considered important infection control measures. Since contact precautions are costly and may negatively impact patient care, rapid exclusion of ESBL carriage and therefore earlier discontinuation of contact precautions are desired. AIM: In the present study, the performance of an ESBL PCR targeting blaCTX-M genes was evaluated as a screening assay for ESBL carriage...
October 25, 2017: Journal of Hospital Infection
Malin Alsved, Anette Civilis, Peter Ekolind, Ann Tammelin, Annette Erichsen Andersson, Jonas Jakobsson, Tobias Svensson, Matts Ramstorp, Sasan Sadrizadeh, Per-Anders Larsson, Mats Bohgard, Tina Šantl-Temkiv, Jakob Löndahl
AIM: To evaluate three types of ventilation systems for operating rooms with respect to air cleanliness (in colony forming units, CFU/m(3)), energy consumption, and working environment comfort (noise and draught) as reported by surgical team members. METHODS: Two commonly used ventilation systems, vertical laminar airflow (LAF) and turbulent mixed airflow (TMA), were compared with a newly developed ventilation technique: temperature controlled airflow (TcAF). CFU concentrations were measured at three locations in an operating room during 45 orthopaedic surgeries: close to the wound (<40 cm), at the instrument table, and peripherally in the room...
October 23, 2017: Journal of Hospital Infection
H Ciesielczuk, L M Phee, H Dolphin, M Wilks, B P Cherian, D W Wareham
BACKGROUND: Successful laboratory detection of carbapenemase-producing Enterobacteriaceae (CPE) in patient surveillance samples is a diagnostic challenge. In the absence of a gold standard for screening rectal swabs for CPE many phenotypic, genotypic, culture and non-culture based assays have been proposed for identifying these bacteria. AIM: To develop and optimise a CPE screening protocol capable of identifying all commonly encountered CPE, including those producing OXA-48-like carbapenemases...
October 23, 2017: Journal of Hospital Infection
Tasnuva Rashid, Kelley Poblete, Jonathan Amadio, Irtiza Hasan, Khurshida Begum, M Jahangir Alam, Kevin W Garey
BACKGROUND: Recently, a UVC decontamination device has become available that delivers germicidal UVC radiation to shoe soles. The objective of this study were to demonstrate that shoe soles can be vectors for healthcare associated infection and whether a UVC shoe sole decontamination device would be effective at decreasing this risk. METHODOLOGY: Three bacterial strains (Staphylococcus aureus, Enterococcus faecalis, and Escherichia coli, and a non-toxigenic strain of Clostridium difficile were spiked onto standardized rubber soled shoe soles and then randomly selected to UVC exposure or no UVC exposure...
October 21, 2017: Journal of Hospital Infection
A P Marchi, L V P Neto, R C R Martins, C F Rizek, C H Camargo, L Z Moreno, A M Moreno, M V Batista, M S Basqueira, F Rossi, U Amigo, T Guimaraes, A S S Levin, S F Costa
Vancomycin-resistant enterococci (VRE) are an important agent of colonization and infection in haematology patients. However, the role of virulence on VRE colonization and infection is controversial. The aim of this study was to characterize the lineage, virulence and resistance profile of VRE infection and colonization isolates; as well as their impact on outcome of haematology patients using a regression logistic model. METHODS: Eighty-six isolates (80 Enterococcus faecium and 6 E. faecalis) from 76 patients were evaluated...
October 21, 2017: Journal of Hospital Infection
Yang Li, Xiao-Li Cao, Hai Ge, Yi-Hong Jiang, Hong Zhou, Wei Zheng
BACKGROUND: Nosocomial infections (NIs) impact care and costs in hospitals across the globe. There are minimal data on targeted surveillance of NI in intensive care units (ICUs), and data specific to the risk factors for NI are especially limited. METHODS: One hundred seventy-seven secondary and tertiary hospitals performed NI targeted surveillance in their ICUs. The data were collected and summarized by Minke software, then fed back once per quarter. RESULTS: The incidence of NI appeared to decrease, and the incidence of NI per 1000 patient-days and adjusted incidence were 25...
October 16, 2017: Journal of Hospital Infection
Luigi Principe, Elisa Meroni, Viola Conte, Carola Mauri, Vincenzo Di Pilato, Tommaso Giani, Paolo Bonfanti, Gian Maria Rossolini, Francesco Luzzaro
No abstract text is available yet for this article.
October 14, 2017: Journal of Hospital Infection
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