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International Endodontic Journal

J S Takanche, Y-H Lee, J-S Kim, J-E Kim, S-H Han, S-W Lee, H-K Yi
AIM: To examine the properties of Schisandrin C as an anti-inflammatory and anti-oxidant compound, and whether its characteristics promote mitochondrial biogenesis in human dental pulp cells (HDPCs). METHODOLOGY: HDPCs were extracted from fresh third molars and cultured for experiments. Reactive oxidative stress (ROS) and nitric oxide (NO) formation were analyzed by a Muse cell analyzer. Western blotting and gelatin zymography were used to identify the presence of anti-oxidants, as well as anti-inflammatory and mitochondrial biogenesis with specific antibody...
September 12, 2017: International Endodontic Journal
R Sako, F Kobayashi, N Aida, M Furusawa, T Muramatsu
AIM: To investigate the proliferation and migration of Epithelial cell rests of Malassez (ERM) after stimulation with IL-6. METHODOLOGY: Porcine-derived ERM were seeded on Dulbecco's modified Eagle's Medium and IL-6 (100 pg/mL) was incorporated into the culture medium. The WST-1 assay was performed to evaluate cell proliferation, and absorption was measured at 450 nm. A wound healing assay and immunofluorescence assay for integrin α3 were conducted in order to investigate migration...
September 12, 2017: International Endodontic Journal
S-H Nam, S-M Ok, G-C Kim
AIM: To evaluate the structural-morphological changes in enamel surface roughness and Streptococcus mutans adhesion after tooth bleaching using plasma in combination with a low concentration of 15% carbamide peroxide (CP). METHODOLOGYS: Sixty pairs of premolars were randomly assigned to the treatment groups (n = 30; buccal surface, Groups 1A/2A) or controls (n = 30; palatal surface, Groups 1B/2B). Group 1A received a low concentration of 15% CP and low-temperature plasma...
September 12, 2017: International Endodontic Journal
C J Tomás-Catalá, M Collado-González, D García-Bernal, R E Oñate-Sánchez, L Forner, C Llena, A Lozano, P Castelo-Baz, J M Moraleda, F J Rodríguez-Lozano
AIM: To evaluate the biological effects in vitro of MTA Angelus (MTA-Ang; Angelus, Londrina, PR, Brazil), MTA Repair HP (MTA-HP; Angelus,) and NeoMTA Plus (NeoMTA-P; Avalon Biomed Inc, Bradenton, FL, USA) on human dental pulp stem cells (hDPSCs). METHODOLOGY: Cell viability and cell migration assays were performed using eluates of each material. To evaluate cell morphology and cell attachment to the different materials, hDPSCs were directly seeded onto the material surfaces and analyzed by immunocytofluorescence and scanning electron microscopy, respectively...
September 11, 2017: International Endodontic Journal
R Silva-Neto, M Sousa-Neto, J Pecora, R Palma-Dibb, A Souza-Gabriel
AIM: To evaluate the wear of root wall surfaces, the bond strength of sealers to dentine and the demineralization around filling material after the canals were exposed to acid challenge. METHODOLOGY: Eighty-seven roots of mandibular incisors were selected. Thirty-two were used in the bond strength in vitro study (n=8) and 55 in the in situ study (n=11). Root canals were prepared biomechanically and then filled with gutta-percha and AH Plus, MTA Fillapex, Sealapex or Endofill...
September 8, 2017: International Endodontic Journal
F Siboni, P Taddei, F Zamparini, C Prati, M G Gandolfi
AIM: To evaluate the chemical and physical properties of a tricalcium silicate root canal sealer containing povidone and polycarboxylate (BioRoot RCS), a calcium silicate MTA based sealer containing a salicylate resin (MTA Fillapex), a traditional eugenol-containing sealer (Pulp Canal Sealer) and an epoxy resin-based root canal sealer (AH Plus). METHODOLOGY: Calcium release, pH, setting time, water sorption, (volume of open pores, volume of impervious portion, apparent porosity) porosity and weight loss were measured...
September 7, 2017: International Endodontic Journal
S A Mahasneh, K Horner, J Cunliffe, S Al-Salehi, A Sengupta, A AlHadidi
AIM: To identify guidelines on endodontics which make recommendations relating to post-root canal treatment radiological review imaging, to make an objective assessment of their quality using the AGREE tool and to examine the evidence cited in support of their recommendations. METHODOLOGY: The primary sources to identify published guidelines were MEDLINE (Ovid(®) ) and EMBASE. The search aim was to identify guidelines pertaining to the post-root canal treatment follow-up recommendations published from 1946 with the final search date being 26 June 2016...
September 7, 2017: International Endodontic Journal
E Petitjean, A Mavridou, X Li, E Hauben, E Cotti, P Lambrechts
AIM: To achieve a better understanding of a calcified extraradicular deposit on the apical root surfaces of a mandibular first molar associated with a radicular cyst and a sinus tract. A multimodular approach was applied using a combination of multiple investigation methods. SUMMARY: This case report presents a mandibular first molar with a calcified extraradicular deposit on the apical root surfaces of both roots. An apical periodontitis lesion was present and a sinus tract served as the only communication with the oral cavity...
September 2, 2017: International Endodontic Journal
D M Ribeiro, J C Réus, W T Felippe, C Pachêco-Pereira, K L Dutra, J N Santos, A L Porporatti, G De Luca Canto
The technical quality of root canal treatment (RCT) may impact on the outcome. The quality of education received during undergraduate school may be linked to the quality of treatment provided in general dental practice. In this context, the aim of this systematic-review is to answer the following focused questions: 1) What is the frequency of acceptable technical quality of root fillings, assessed radiographically, performed by undergraduate students? 2) What are the most common errors assessed radiographically and reported in these treatments? For this purpose, articles that evaluated the quality of root fillings performed by undergraduate students were selected...
September 1, 2017: International Endodontic Journal
B Eren, E O Onay, M Ungor
AIM: To evaluate three emergency procedures for their ability to alleviate clinical symptoms associated with symptomatic teeth having signs of (at least) partial irreversible pulpitis. METHODOLOGY: Sixty-six maxillary and mandibular molars were randomly assigned to a total pulpectomy group (TP; n=22), partial pulpectomy group (PP; n=22), or pulpotomy group (P; n=22). Procedure durations were recorded. Patients answered a questionnaire on daily analgesic requirements and about clinical symptoms (pain intensity, chewing sensitivity, and thermal sensitivity) after the anaesthetic effect had disappeared (Day 0) and on Days 1, 3, and 7 post-treatment...
August 30, 2017: International Endodontic Journal
L L Ferreira, J E Gomes-Filho, F Benetti, M Carminatt, E Ervolino, A L F Briso, L T A Cintra
AIM: To evaluate the influence of dental bleaching in immunoregulatory cytokines production (IL-6, TNF-α, and IL-17) in the pulp tissue of normoglycaemic and diabetic rats. METHODOLOGY: Twenty-eight rats were divided in normoglycaemic and diabetic rats (n = 14). Diabetes mellitus (DM) was induced with a single dose of alloxan diluted in citrate buffer via intramuscular injection. After DM confirmation, all rats were sedated and dental bleaching was performed using 35% hydrogen peroxide in the right maxillary molars for 30 minutes...
August 30, 2017: International Endodontic Journal
T Rödig, C Müller, M Hoch, F Haupt, X Schulz, A Wiegand, M Rizk
AIM: To evaluate the effect of moisture content in root canal dentine on detection of microcracks using micro-computed tomography. METHODOLOGY: Ten roots with and without craze lines or cracks (each n = 5) were selected and scanned six times with different moisture conditions of root dentine using a micro-CT scanner at a high resolution of 10.5 μm. Scanning conditions were as follows: 1. after 30 d wet storage, 2. after 2 h dry time, 3. after 48 h wet storage, 4...
August 30, 2017: International Endodontic Journal
C M Ribeiro, M L de Carli, S Nonogaki, D A Nogueira, A A C Pereira, F F Sperandio, J A C Hanemann
AIM: To evaluate the participation of both Th1 and Th2 responses in periapical cysts by assessing the presence of M2 macrophages, as well as acute IL-1 β, TNF-α and IL-6 cytokines. METHODOLOGY: Twenty-four cases of periapical cysts were selected. Immuno-expressions of IL-1 β, IL-6, TNF-α and CD163 were analyzed in the cystic capsules in both superficial and deeper regions. Data were analyzed with paired Wilcoxon test and Spearman correlation coefficient (P ≤ ...
August 30, 2017: International Endodontic Journal
G Uslu, T Özyürek, K Yılmaz, M Gündoğar
AIM: To examine the cyclic fatigue resistances of R-Pilot, HyFlex EDM, and PathFile NiTi glide path files in S-shaped artificial canals. METHODOLOGY: Twenty R-Pilot (12.5/.04), 20 HyFlex EDM (10/.05) and 20 PathFile (19/.02) single-file glide path files were included. Sixty files (n: 20/each) were subjected to static cyclic fatigue testing by using double-curved canals until fracture occurred (TF). The number of cycles to fracture (NCF) was calculated by multiplying the rpm value by the TF...
August 30, 2017: International Endodontic Journal
M Zarow, A Ramírez-Sebastià, P Gaetano, J de Ribot Porta, J Mora, J Espona, F Durán-Sindreu, M Roig
The aim of this paper was to: a) review the current literature on the status of root filled teeth, b) analyse the most important factors in decision-making, c) discuss the current restorative concepts, d) classify both the evidence and clinical practice in a way that seeks to be clear, understandable and helpful for clinicians. Restoration of root filled teeth represents a challenge for the clinician and remains a controversial subject. The guidelines describe a new classification that is drawn from evidence presented in the literature and also from clinical expertise-based reviews...
August 29, 2017: International Endodontic Journal
G Gambarini, P Ropini, L Piasecki, R Costantini, E Carneiro, L Testarelli, P M H Dummer
AIM: To investigate in vivo the complexity of canals within mesial roots of mandibular molars using 3D Endo(™) software linked to CBCT images. METHODOLOGY: The CBCT images of 100 mandibular first molars were analyzed using the 3D Endo(™) software. The number of canals in the mesial roots, the presence of apical confluences, the canal lengths and the canal configurations using Vertucci's classification were evaluated in bucco-lingual (BL) and mesio-distal (MD) views...
August 29, 2017: International Endodontic Journal
N Al-Nuaimi, S Patel, A Davies, A Bakhsh, F Foschi, F Mannocci
AIM: To provide an estimate of the proportion of successful outcomes of primary and secondary root canal treatments (retreatments) determined by periapical radiographs and cone beam computed tomography (CBCT), a pooled analysis of the data collected from three previous prospective clinical outcome studies was undertaken. METHODOLOGY: The analysis pooled the 1-year results for 354 teeth, including 123 primary treatments and 231 retreatments. All root canals were instrumented with ProTaper Universal and filled using a warm vertical condensation technique...
August 28, 2017: International Endodontic Journal
A Keleş, C Keskin
AIM: To conduct a quantitative and qualitative analysis of the band-shaped isthmus area, the floor of which was in the apical third in the mesial roots of mandibular first molars using micro-computed tomography (micro-CT). METHODOLOGY: Micro-CT images of 269 mesial roots of mandibular first molars were evaluated, and 40 specimens with a band-shaped isthmus, with a floor in the apical third, were selected. The major diameter, minor diameter, roundness, area and perimeter values for the most coronal and apical slices where the isthmus was visible were measured...
August 28, 2017: International Endodontic Journal
M Torabinejad, M Parirokh, P M H Dummer
Mineral trioxide aggregate (MTA) is a dental material used extensively for vital pulp therapy (VPT), scaffold cover during regenerative endodontic procedures, apical barrier in teeth with necrotic pulps and open apices, perforation repair, and root canal filling and root-end filling during surgical endodontics. A number of bioactive endodontic cements (BECs) have recently been introduced to the market. Most of these materials had calcium and silicate in their compositions; however, the bioactivity is the common property of these cements...
August 28, 2017: International Endodontic Journal
M Parirokh, M Torabinejad, P M H Dummer
Mineral trioxide aggregate (MTA) is a bioactive endodontic cement (BEC) mainly comprised of calcium and silicate elements. The cement was introduced by Torabinejad in the 1990s and has been approved by the Food and Drug Administration (FDA) to be used in the U.S. in 1997. A number of new Bioactive Endodontic Cements (BECs) have also been introduced to the market, including BioAggregate, Biodentine, BioRoot RCS, calcium enriched mixture (CEM) cement, CAPSEAL, Endo-CPM, Endocem, EndoSequence, EndoBinder, EndoSeal MTA, iRoot, MicroMega MTA, MTA Bio, MTA Fillapex, MTA Plus, Neo MTA Plus, Ortho MTA, Quick-Set, Retro MTA, Tech Biosealer, and TheraCal...
August 24, 2017: International Endodontic Journal
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