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International Endodontic Journal

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https://www.readbyqxmd.com/read/28218959/survival-and-periapical-health-after-root-canal-treatment-with-carrier-based-root-fillings-5-year-retrospective-assessment
#1
C Pirani, S Friedman, M R Gatto, F Iacono, V Tinarelli, M G Gandolfi, C Prati
AIM: This retrospective study explored survival and periapical healing outcomes in root filled teeth with Thermafil obturators. METHODOLOGY: Root canals of 213 teeth (94 subjects, mean age 48±13 years), instrumented with a step-down technique, irrigated with 5% NaOCl and 10% EDTA and filled with Thermafil and AH-Plus sealer, were involved in a Recall programme. Teeth were retrospectively reexamined after 5±1 years in a controlled environment. Clinical and radiographic data that were collected included: preoperative Periapical Index (PAI) score and signs/symptoms, treatment type, root filling length and presence/absence of voids, restoration type, follow-up PAI score and signs/symptoms...
February 20, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28218957/cyclic-fatigue-resistance-of-a-novel-rotary-file-manufactured-using-controlled-memory-ni-ti-technology-compared-to-a-file-made-from-m-wire-file
#2
E Alshwaimi
AIM: To compare the cyclic fatigue properties of a novel file made using controlled memory NiTi technology with those of files made from M-wire. METHODOLOGY: Twelve files with similar cross-sectional geometry and tip size from each of the following groups were tested: Proflexendo made from CMT (PE; size 30 .04) (Nexden, Houston, Tx, USA), ProFile Vortex made from M-wire (PV; size 30 .04) (Dentsply Tulsa Dental, Tulsa, OK, USA), and ProTaper Universal made from regular alloy (PU; F3) (Dentsply Tulsa Dental)...
February 20, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28214370/the-effect-of-pre-operative-submucosal-administration-of-tramadol-on-the-success-rate-of-inferior-alveolar-nerve-blocks-on-mandibular-molars-with-acute-irreversible-pulpitis-a-randomized-double-blind-clinical-trial
#3
A De Pedro-Muñoz, J Mena-Álvarez
AIM: This randomized, double-blind, placebo controlled, clinical trial was designed to improve the success of inferior alveolar nerve blocks (IANB) in mandibular molars with symptomatic irreversible pulpitis (SIP) by means of pre-operative submucosal administration of 50mg tramadol. METHODOLOGY: Forty-two patients with a mandibular molar diagnosed with symptomatic irreversible pulpitis took part in the trial. Patients were assigned randomly to one of two groups: tramadol group (n=21), who received 50mg tramadol in 1mL by mandibular infiltration, and a placebo group (n=21), who received 1 mL of normal saline administered to the affected tooth by the same means...
February 18, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28211068/dentine-matrix-proteins-isolation-and-effects-on-human-pulp-cells
#4
M Widbiller, A Eidt, S R Lindner, K-A Hiller, H Schweikl, W Buchalla, K M Galler
AIM: To establish a simplified and efficient protocol for the isolation and concentration of matrix proteins from human dentine, and to assess the effects of extracted dentine matrix proteins (eDMP) on the behavior of human pulp cells. METHODOLOGY: Matrix proteins were isolated from human dentine, purified, concentrated and characterized with protein and enzyme-linked immunosorbent assays. Culture media were supplemented with eDMP in different concentrations, referred to as eDMP 1 to 10,000, to assess viability and proliferation of human pulp cells by DNA and MTT assays; apoptotic events were quantified by flow cytometry...
February 17, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28196289/what-happens-to-unprepared-root-canal-walls-a-correlative-analysis-using-micro-computed-tomography-and-histology-scanning-electron-microscopy
#5
J F Siqueira, A R Pérez, M F Marceliano-Alves, J C Provenzano, S G Monteros, F R Pires, G C S Vieira, I N Rôças, F R F Alves
AIM: To microscopically examine the cleaning conditions of root canal walls that remained unprepared as revealed by micro-CT. METHODOLOGY: The root canals of 10 freshly extracted mandibular premolars with necrotic pulps and apical periodontitis along with the mesiobuccal canals of 11 mandibular molars with vital pulps were prepared using Reciproc instruments R40 and R25, respectively, and 2.5% sodium hypochlorite irrigation. Specimens were scanned in micro-CT before and after preparation and the unprepared areas were identified...
February 14, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28196285/morphological-evaluation-of-maxillary-second-molars-with-fused-roots-a-micro-ct-study
#6
R Ordinola-Zapata, J N R Martins, C M Bramante, M H Villas-Boas, M H Duarte, M A Versiani
AIM: To evaluate the internal and external morphologies of fused-rooted maxillary second molars by means of micro-computed tomography (micro-CT) analysis. METHODOLOGY: One-hundred fused-rooted maxillary second molars from a Brazilian subpopulation were divided into six groups according to the root morphology. The samples were scanned at a resolution of 19.6 μm, and evaluated with regards to the external morphology of the roots, the root canal configuration, the percentage frequency of C-shaped canals and isthmuses, as well as, the morphology of the root canal system at 1, 2 and 3 mm from the anatomic apex of the fused roots...
February 14, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28169432/cytotoxicity-and-bioactivity-of-various-pulpotomy-materials-on-stem-cells-from-human-exfoliated-primary-teeth
#7
M Collado-González, D García-Bernal, R E Oñate-Sánchez, P S Ortolani-Seltenerich, T Álvarez Muro, A Lozano, L Forner, C Llena, J M Moraleda, F J Rodríguez-Lozano
AIMS: To investigate the cytotoxicity and bioactivity of several pulpotomy materials: Biodentine (Septodont, Saint- Maur-des-Fosses, France) MTA (Angelus, Londrina, PR, Brazil), Theracal LC (Bisco Inc., Schamburg, IL, USA) and IRM (Dentsply DeTrey GmbH, Konstanz, Germany), after contact with stem cells isolated from human exfoliated deciduous teeth (SHEDs). METHODOLOGY: SHEDs were cultured in the presence of the eluates of various pulpotomy materials for 24, 48 and 72h...
February 7, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28134990/cytotoxicity-of-peracetic-acid-evaluation-of-effects-on-metabolism-structure-and-cell-death
#8
K S Viola, E M Rodrigues, M Tanomaru-Filho, I Z Carlos, S G Ramos, J M Guerreiro-Tanoamru, G Faria
AIM: To evaluate the cytotoxicity and the mechanism of cell aggression of peracetic acid (PA) in comparison with sodium hypochlorite (NaOCl). METHODOLOGY: L929 fibroblasts were exposed to 1% PA and 2.5% NaOCl, in different dilutions for 10 minutes. The following parameters were evaluated: cell metabolism by methylthiazol tetrazolium assay (MTT), external morphology by scanning electron microscopy, ultrastructure by transmission electron microscopy, the cytoskeleton by means of actin and α-tubulin labeling, and the type of cell death by flow cytometry (apoptosis/necrosis)...
January 30, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28134983/effect-of-two-different-concentrations-of-sodium-hypochlorite-on-postoperative-pain-following-single-visit-root-canal-treatment-a-triple-blind-randomized-clinical-trial
#9
S Farzaneh, M Parirokh, N Nakhaee, P V Abbott
AIM: To compare the effects of two different concentrations of NaOCl solution on postoperative pain following single-visit root canal treatment in mandibular molars with irreversible pulpitis. METHODOLOGY: A total of 122 patients who had mandibular molars with irreversible pulpitis were treated. The patients were randomly divided into two groups according to the concentration of NaOCl used during root canal instrumentation - either 2.5% or 5.25%. RaCe rotary instruments were used for root canal preparation and all root canals were filled in one visit...
January 30, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28129447/the-comparative-effectiveness-and-safety-of-three-activated-irrigation-techniques-in-the-isthmus-area-using-a-transparent-tooth-model
#10
A Malentacca, U Uccioli, F Mannocci, B Bhuva, D Zangari, C Pulella, C Lajolo
AIM: To compare the effectiveness and safety of three activated irrigation techniques when removing pulp tissue from the isthmus of a transparent tooth model. The three techniques assessed were: the EndoVac (EV), passive ultrasonic irrigation (PUI) and ultrasonic wave aspiration (TUWA). Conventional syringe irrigation (CSI) was used as a control. METHODOLOGY: A transparent tooth model was created using the mesial root of an extracted mandibular first molar that had an isthmus and two independent mesial canals...
January 27, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28117904/the-effect-of-accelerated-mineral-trioxide-aggregate-on-odontoblastic-differentiation-in-dental-pulp-stem-cell-niches
#11
P Kulan, O Karabiyik, G T Kose, B Kargul
AIM: To investigate the effect of accelerated-set mineral trioxide aggregate (MTA) on the proliferation and odontoblastic differentiation of human dental pulp cell niches (DPSC). METHODOLOGY: ProRoot White MTA (WMTA) (Dentsply Tulsa Dental, Johnson City, TN, USA) was mixed with various additives, which included distilled water, 2.5% disodium hydrogen phosphate (Na2 HPO4 )(Merck, Darmstadt, Germany) and 5% calcium chloride (CaCl2 )(Merck). DPSC niches extracted from third molars were cultured directly on MTA in the culture medium...
January 24, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28109163/an-assessment-of-the-overexpression-of-bmp-2-in-transfected-human-osteoblast-cells-stimulated-by-mta-and-biodentine
#12
E M Rodrigues, A L G Cornélio, A S C Fuentes, L P Salles, M Velayutham, C Rossa-Junior, J M Guerreiro-Tanomaru, M Tanomaru-Filho
AIM: To evaluate the effect of MTA and Biodentine on viability, osteogenic differentiation and BMP-2 expression in osteogenic cells. METHODOLOGY: Saos-2 cells were used as a model of osteoblastic cells. Overexpression of BMP2 was induced by transfection of a CMV-driven plasmid construct including the human BMP-2 coding sequence and stably transfected cells were selected. Cell viability was assessed by the mitochondrial dehydrogenase enzymatic (MTT) assay. The bioactivity of the materials was evaluated by the Alkaline Phosphatase (ALP) assay and detection of calcium deposits with Alizarin Red Staining (ARS)...
January 21, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28109162/odontoblastic-differentiation-of-dental-pulp-stem-cells-from-healthy-and-carious-teeth-on-an-original-pcl-based-3d-scaffold
#13
A Louvrier, E Euvrard, L Nicod, G Rolin, F Gindraux, L Pazart, C Houdayer, P Y Risold, F Meyer, C Meyer
AIMS: To isolate and characterize Dental Pulp Stem Cells (DPSCs) obtained from carious and healthy mature teeth extracted when conservative treatment was not possible or for orthodontic reasons; to evaluate the ability of DPSCs to colonize, proliferate, and differentiate into functional odontoblast-like cells when cultured onto a polycaprolactone cone made by jet-spraying and prototyped into a design similar to a gutta-percha cone. METHODOLOGY: DPSCs were obtained from 9 carious and 12 healthy mature teeth...
January 21, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28097666/understanding-external-cervical-resorption-patterns-in-endodontically-treated-teeth
#14
M Mavridou, E Hauben, M Wevers, E Schepers, L Bergmans, P Lambrechts
AIM: To understand the pattern of external cervical resorption (ECR) in endodontically treated teeth. To compare characteristics and mechanisms of ECR in root filled teeth with those established in teeth with vital pulps. METHODOLOGY: Seven cases of endodontically treated permanent teeth displaying ECR were investigated. ECR diagnosis was based on clinical findings and radiographic examination with cone-beam computed tomography (CBCT). The extracted teeth were further analysed by a nano-focus computed tomographic (nano-CT) system, hard tissue histology and scanning electron microscopy (SEM)...
January 18, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28095624/-it-s-good-enough-swedish-general-dental-practitioners-on-reasons-for-accepting-sub-standard-root-filling-quality
#15
L Dahlström, O Lindwall, H Rystedt, C Reit
AIM: The concept of "good enough" is central and necessary in the assessment of root filling quality. The aim was to explore the concept by analysing reasons and arguments for the acceptance or rejection of substandard root filling quality as reported by GDPs in Sweden. METHODOLOGY: The study was designed as a qualitative and exploratory study based on seven videotaped focus group interviews analysed by means of qualitative content analysis. Thirty-three general dental practitioners (GDPs) employed in the Public Dental Health Service in Gothenburg, Sweden, participated (4-6 GDPs/interview)...
January 17, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28039864/sirtuin-6-attenuates-periapical-lesion-propagation-by-modulating-hypoxia-induced-ccl2-production-in-osteoblasts
#16
Y-L Lee, S-K Lin, K-L Hou, S-H Kok, E H-H Lai, H-W Wang, J Z-C Chang, H Yang, C-Y Hong
AIM: To investigate the attenuating effect of sirtuin 6 (SIRT6) on hypoxia-induced production of chemokine (C-C motif) ligand 2 (CCL2) by osteoblasts and the relevance of this action on the pathogenesis of periapical lesions. METHODOLOGY: SIRT6 was overexpressed in MC3T3-E1 murine osteoblasts by lentivirus-mediated gene transfer. The relationship between the anti-glycolytic/anti-oxidative activities of SIRT6 and its effect on hypoxia-induced CCL2 production were examined...
December 31, 2016: International Endodontic Journal
https://www.readbyqxmd.com/read/28005295/antibiotics-in-endodontics-a-review
#17
REVIEW
J J Segura-Egea, K Gould, B Hakan Şen, P Jonasson, E Cotti, A Mazzoni, H Sunay, L Tjäderhane, P M H Dummer
The overuse of antibiotics and the emergence of antibiotic-resistant bacterial strains is a global concern. This concern is also of importance in terms of the oral microbiota and the use of antibiotics to deal with oral and dental infections. The aim of this paper is to review the current literature on the indications and use of antibiotics and to make recommendations for their prescription in endodontic patients. Odontogenic infections, including endodontic infections, are polymicrobial, and in most cases, the prescription of antibiotics is empirical...
December 22, 2016: International Endodontic Journal
https://www.readbyqxmd.com/read/27987307/prevalence-and-nature-of-fungi-in-root-canal-infections-a-systematic-review-and-meta-analysis
#18
REVIEW
I F Persoon, W Crielaard, A R Özok
The role of bacteria in causing apical periodontitis has been widely established, while the role of other microorganisms is studied less thoroughly. This systematic review and meta-analysis reviewed the literature for the prevalence and diversity of fungi in root canal infections. An extensive literature search was done in the Cochrane databases, EMBASE, MEDLINE, LILACS, SciELO and Web of Science. Additional studies were identified from six endodontic journals, four main endodontic textbooks and references of relevant papers...
December 17, 2016: International Endodontic Journal
https://www.readbyqxmd.com/read/27977869/endodontic-treatment-related-antibiotic-prescribing-patterns-of-south-african-oral-health-professionals
#19
R Lalloo, G Solanki, K Ramphoma, N G Myburgh
AIM: To assess the antibiotic prescribing patterns of South African dentists for patients undergoing endodontic treatment. METHODOLOGY: This study used data from 2013 health insurance claims submitted by South African oral health professionals to determine the antibiotic prescribing patterns related to endodontic treatment. A logistic regression model was used to test the fully adjusted statistical significance of the association between the exploratory variables (gender, age group, event type, abscess treatment, chronic health) and the dependent variable (antibiotic prescription)...
December 15, 2016: International Endodontic Journal
https://www.readbyqxmd.com/read/27977866/effect-of-simulated-pulpal-blood-flow-rate-on-the-rise-in-pulp-chamber-temperature-during-direct-fabrication-of-exothermic-provisional-restorations
#20
R I Farah
AIM: To evaluate ex vivo the effect of several simulated pulpal blood flow rates on the change in pulp chamber temperature during direct fabrication of a provisional restoration using a polymethylmethacrylate (PMMA) resin. METHODOLOGY: Fifteen noncarious human premolars were prepared for complete coverage restorations. A curved needle connected to a peristaltic pump simulated the pulp blood flow. Two K-type thermocouples connected to a digital thermometer were placed in the pulp chamber, and the assembly was placed in an incubator at 37 °C...
December 15, 2016: International Endodontic Journal
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