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AJNR. American Journal of Neuroradiology

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https://www.readbyqxmd.com/read/30002055/clinically-relevant-imaging-features-for-mgmt-promoter-methylation-in-multiple-glioblastoma-studies-a-systematic-review-and-meta-analysis
#1
C H Suh, H S Kim, S C Jung, C G Choi, S J Kim
BACKGROUND: O6-methylguanine methyltransferase ( MGMT ) promoter methylation status has been reported as a prognostic biomarker in clinical trials. PURPOSE: Our aim was to systematically evaluate imaging features of MGMT promoter methylated glioblastoma and to determine the diagnostic performance of MR imaging for prediction of MGMT promoter methylation in patients with newly diagnosed glioblastoma. DATA SOURCES: A computerized search of Ovid MEDLINE and EMBASE up to February 27, 2018, was conducted...
July 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/30002054/preoperative-mapping-of-the-supplementary-motor-area-in-patients-with-brain-tumor-using-resting-state-fmri-with-seed-based-analysis
#2
J Wongsripuemtet, A E Tyan, A Carass, S Agarwal, S K Gujar, J J Pillai, H I Sair
BACKGROUND AND PURPOSE: The supplementary motor area can be a critical region in the preoperative planning of patients undergoing brain tumor resection because it plays a role in both language and motor function. While primary motor regions have been successfully identified using resting-state fMRI, there is variability in the literature regarding the identification of the supplementary motor area for preoperative planning. The purpose of our study was to compare resting-state fMRI to task-based fMRI for localization of the supplementary motor area in a large cohort of patients with brain tumors presenting for preoperative brain mapping...
July 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/30002053/clinical-utility-of-a-novel-ultrafast-t2-weighted-sequence-for-spine-imaging
#3
M B Keerthivasan, B Winegar, J L Becker, A Bilgin, M I Altbach, M Saranathan
BACKGROUND AND PURPOSE: TSE-based T2-weighted imaging of the spine has long scan times. This work proposes a fast imaging protocol using variable refocusing flip angles, optimized for blurring and specific absorption rate. MATERIALS AND METHODS: A variable refocusing flip angle echo-train was optimized for the spine to improve the point spread function and minimize the specific absorption rate, yielding images with improved spatial resolution and SNR compared with the constant flip angle sequence...
July 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/30002052/application-of-3d-fast-spin-echo-t1-black-blood-imaging-in-the-diagnosis-and-prognostic-prediction-of-patients-with-leptomeningeal-carcinomatosis
#4
J Oh, S H Choi, E Lee, D J Shin, S W Jo, R-E Yoo, K M Kang, T J Yun, J-H Kim, C-H Sohn
BACKGROUND AND PURPOSE: Contrast-enhanced 3D fast spin-echo T1 black-blood imaging selectively suppresses the signal of blood flow and could provide a higher contrast-to-noise ratio compared with contrast-enhanced 3D ultrafast gradient recalled echo (contrast-enhanced gradient recalled echo) and 2D spin-echo T1WI (contrast-enhanced spin-echo). The purpose of our study was to evaluate whether black-blood imaging can improve the diagnostic accuracy for leptomeningeal carcinomatosis compared with contrast-enhanced gradient recalled-echo and contrast-enhanced spin-echo and, furthermore, to determine whether the grade of leptomeningeal carcinomatosis evaluated on black-blood imaging is a significant predictor of progression-free survival...
July 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/30002051/ultrafast-brain-mri-can-be-used-for-indications-beyond-shunted-hydrocephalus-in-pediatric-patients
#5
A Tekes, S S Senglaub, E S Ahn, T A G M Huisman, E M Jackson
BACKGROUND AND PURPOSE: Evaluation of shunted hydrocephalus is the most common indication for ultrafast brain MRI. Radiation-/sedation-free imaging capabilities make this protocol more desirable over CT and standard brain MRI. We hypothesized that ultrafast brain MRI can be used for selected indications beyond shunted hydrocephalus without adverse outcomes. MATERIALS AND METHODS: Ultrafast brain MRI was performed with axial, sagittal, and coronal HASTE. The radiology information system was used to identify pediatric patients (0-18 years of age) who underwent ultrafast brain MRI between March 2014 and May 2016...
July 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29976834/primary-angioplasty-without-stenting-for-symptomatic-high-grade-intracranial-stenosis-with-poor-circulation
#6
Y Wang, Y Ma, P Gao, Y Chen, B Yang, L Jiao
BACKGROUND AND PURPOSE: Although the Stenting versus Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) study demonstrated a high incidence of perioperative complications for Intracranial Atherosclerotic disease (ICAD) treatments with stent placement, some studies have shown that submaximal angioplasty with an undersized balloon limits the risks of perioperative complications, suggesting that intervention may remain an alternative option for ICAD if perioperative complications are minimized...
July 5, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29976833/impact-of-focal-white-matter-damage-on-localized-subcortical-gray-matter-atrophy-in-multiple-sclerosis-a-5-year-study
#7
T A Fuchs, K Carolus, R H B Benedict, N Bergsland, D Ramasamy, D Jakimovski, B Weinstock-Guttman, A Kuceyeski, R Zivadinov, M G Dwyer
BACKGROUND AND PURPOSE: It is unclear to what extent subcortical gray matter atrophy is a primary process as opposed to a result of focal white matter damage. Correlations between WM damage and atrophy of subcortical gray matter have been observed but may be partly attributable to indirect relationships between co-occurring processes arising from a common cause. Our aim was to cross-sectionally and longitudinally characterize the unique impact of focal WM damage on the atrophy of connected subcortical gray matter regions, beyond what is explainable by global disease progression...
July 5, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29976832/noncontrast-head-ct-in-children-national-variation-in-radiation-dose-indices-in-the-united-states
#8
G Sadigh, N Kadom, P Karthik, D Sengupta, K J Strauss, D Frush, K E Applegate
BACKGROUND AND PURPOSE: Radiologists should manage the radiation dose for pediatric patients to maintain reasonable diagnostic confidence. We assessed the variation in estimated radiation dose indices for pediatric noncontrast head CT in the United States. MATERIALS AND METHODS: Radiation dose indices for single-phase noncontrast head CT examinations in patients 18 years of age and younger were retrospectively reviewed between July 2011 and June 2016 using the American College of Radiology CT Dose Index Registry...
July 5, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29976831/brain-perfusion-measurements-using-multidelay-arterial-spin-labeling-are-systematically-biased-by-the-number-of-delays
#9
M van der Thiel, C Rodriguez, P Giannakopoulos, M X Burke, R Marc Lebel, N Gninenko, D Van De Ville, S Haller
BACKGROUND AND PURPOSE: Multidelay arterial spin-labeling is a promising emerging method in clinical practice. The effect of imaging parameters in multidelay arterial spin-labeling on estimated cerebral blood flow measurements remains unknown. We directly compared 3-delay versus 7-delay sequences, assessing the difference in the estimated transit time and blood flow. MATERIALS AND METHODS: This study included 87 cognitively healthy controls (78.7 ± 3.8 years of age; 49 women)...
July 5, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29954817/prognostic-value-of-the-metabolic-and-volumetric-parameters-of-11-c-methionine-positron-emission-tomography-for-gliomas-a-systematic-review-and-meta-analysis
#10
Y-I Kim, Y Kim, J Y Lee, S J Jang
BACKGROUND: Several studies have demonstrated that 11 C-methionine positron-emission tomography provides information on prognosis. PURPOSE: We performed a systematic review and meta-analysis of the prognostic value of the metabolic and volumetric parameters of 11 C-methionine-PET for gliomas. DATA SOURCES: A systematic search was performed using the following combination of keywords: "methionine," "PET," "glioma," and "prognosis...
June 28, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29954816/comparative-study-of-mri-biomarkers-in-the-substantia-nigra-to-discriminate-idiopathic-parkinson-disease
#11
N Pyatigorskaya, B Magnin, M Mongin, L Yahia-Cherif, R Valabregue, D Arnaldi, C Ewenczyk, C Poupon, M Vidailhet, S Lehéricy
BACKGROUND AND PURPOSE: Several new MR imaging techniques have shown promising results in patients with Parkinson disease; however, the comparative diagnostic values of these measures at the individual level remain unclear. Our aim was to compare the diagnostic value of MR imaging biomarkers of substantia nigra damage for distinguishing patients with Parkinson disease from healthy volunteers. MATERIALS AND METHODS: Thirty-six patients and 20 healthy volunteers were prospectively included...
June 28, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29954815/assessing-corticospinal-tract-asymmetry-in-unilateral-polymicrogyria
#12
O Foesleitner, K-H Nenning, T Traub-Weidinger, M Feucht, S Bonelli, T Czech, C Dorfer, D Prayer, G Kasprian
BACKGROUND AND PURPOSE: Asymmetry of the corticospinal tract in congenital lesions is a good prognostic marker for preserved motor function after hemispherectomy. This study aimed to assess this marker and provide a clinically feasible approach in selected cases of unilateral polymicrogyria. MATERIALS AND METHODS: Corticospinal tract asymmetry of 9 patients with unilateral polymicrogyria substantially affecting the central region was retrospectively assessed on axial T1WI and DTI...
June 28, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29930097/think-a-head-campaign-of-image-gently-shared-decision-making-in-pediatric-head-trauma
#13
EDITORIAL
N Kadom, B L Vey, D P Frush, J S Broder, K E Applegate
No abstract text is available yet for this article.
June 21, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29930096/morphology-specific-discrimination-between-ms-white-matter-lesions-and-benign-white-matter-hyperintensities-using-ultra-high-field-mri
#14
Z Hosseini, J Matusinec, D A Rudko, J Liu, B Y M Kwan, F Salehi, M Sharma, M Kremenchutzky, R S Menon, M Drangova
BACKGROUND AND PURPOSE: Recently published North American Imaging in Multiple Sclerosis guidelines call for derivation of a specific radiologic definition of MS WM lesions and mimics. The purpose of this study was to use SWI and magnetization-prepared FLAIR images for sensitive differentiation of MS from benign WM lesions using the morphologic characteristics of WM lesions. MATERIALS AND METHODS: Seventeen patients with relapsing-remitting MS and 18 healthy control subjects were enrolled retrospectively...
June 21, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29930095/c1-posterior-arch-flare-point-a-useful-landmark-for-fluoroscopically-guided-c1-2-puncture
#15
M E Peckham, L M Shah, A C Tsai, E P Quigley, J Cramer, T A Hutchins
BACKGROUND AND PURPOSE: The C1-2 intrathecal puncture is routinely performed when lumbar puncture is not feasible. Usage has steadily decreased in part because of the perceived high risk of injury to the cervical cord. Up to this point, vague fluoroscopic guidelines have been used, creating uncertainty about the actual needle location relative to the spinal cord. We present a novel osseous landmark to aid in C1-2 intrathecal puncture, corresponding to the posterior spinal cord margin on lateral fluoroscopic views...
June 21, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29903927/time-course-of-cerebral-perfusion-changes-in-children-with-migraine-with-aura-mimicking-stroke
#16
K M Cobb-Pitstick, N Munjal, R Safier, D D Cummings, G Zuccoli
Hemiplegic migraine is a common cause of acute brain attack in pediatrics. MR imaging sequences useful in differentiating hemiplegic migraine from other entities include arterial spin-labeling, SWI, MRA, and DWI. There has been limited exploration on the simultaneous use of these sequences in pediatrics. We present 12 pediatric patients with acute hemiplegic migraine or migraine with aura who underwent MR imaging within 12 hours of symptom onset. Quantitative and qualitative analyses were performed on arterial spin-labeling; and qualitative analysis, on SWI and MRA sequences...
June 14, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29903926/zonally-magnified-oblique-multislice-and-non-zonally-magnified-oblique-multislice-dwi-of-the-cervical-spinal-cord
#17
M Alizadeh, M M Poplawski, J Fisher, R J T Gorniak, A Dresner, F B Mohamed, A E Flanders
BACKGROUND AND PURPOSE: The zonally magnified oblique multislice EPI (ZOOM-EPI) diffusion-weighted sequence has been visually shown to provide superior MR diffusion image quality compared with the full-FOV single-shot EPI sequence (non-ZOOM-EPI) in the adult cervical spinal cord. The purpose of this study was to examine the diffusion tensor imaging indices in the normal human cervical spinal cord between ZOOMED and non-ZOOMED DTI acquisitions and determine whether DTI values are comparable between direct and indirect age-matched groups...
June 14, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29903925/prognostic-implications-of-gadolinium-enhancement-of-skull-base-chordomas
#18
E Lin, T Scognamiglio, Y Zhao, T H Schwartz, C D Phillips
BACKGROUND AND PURPOSE: Skull base chordomas often demonstrate variable MR imaging characteristics, and there has been limited prior research investigating the potential clinical relevance of this variability. The purpose of this retrospective study was to assess the prognostic implications of signal intensity on standard imaging techniques for the biologic behavior of skull base chordomas. MATERIALS AND METHODS: Medical records were retrospectively reviewed for 22 patients with pathologically confirmed skull base chordomas...
June 14, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29903924/detection-and-characteristics-of-temporal-encephaloceles-in-patients-with-refractory-epilepsy
#19
Z M Campbell, J M Hyer, S Lauzon, L Bonilha, M V Spampinato, M Yazdani
BACKGROUND AND PURPOSE: Temporal encephaloceles are increasingly visualized during neuroimaging assessment of individuals with refractory temporal lobe epilepsy, and their identification could indicate an intracranial abnormality that may be related to a potential seizure focus. Careful review by an experienced neuroradiologist may yield improved detection of TEs, and other clinical, neurophysiologic, and radiologic findings may predict their presence. MATERIALS AND METHODS: Data were reviewed retrospectively in patients at our institution who were presented at a multidisciplinary conference for refractory epilepsy between January 1, 2010, and December 31, 2016...
June 14, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29903923/mr-imaging-features-of-anaplastic-pleomorphic-xanthoastrocytoma-mimicking-high-grade-astrocytoma
#20
D She, J Liu, Z Xing, Y Zhang, D Cao, Z Zhang
BACKGROUND AND PURPOSE: Anaplastic pleomorphic xanthoastrocytoma, which has been recently defined as a distinct entity in the 2016 World Health Organization classification, may exhibit aggressive clinical behavior and relatively worse prognosis than pleomorphic xanthoastrocytoma. This study aimed to investigate whether there were any differences in MR imaging characteristics between these 2 tumors. MATERIALS AND METHODS: This retrospective study included 9 patients with anaplastic pleomorphic xanthoastrocytoma and 10 patients with pleomorphic xanthoastrocytoma who underwent MR imaging before an operation...
June 14, 2018: AJNR. American Journal of Neuroradiology
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