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Ultrastructural Pathology

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https://www.readbyqxmd.com/read/28414554/antitumor-activity-of-the-pachymic-acid-in-nasopharyngeal-carcinoma-cells
#1
Yan-Hua Zhang, Yong Zhang, Xiu-Ying Li, Xu-Dong Feng, Wei Jian, Rong-Qing Li
OBJECTIVE: To investigate the antitumour efficacy of pachymic acid (PA), which is a fungal extract component, on nasopharyngeal carcinoma (NPC) cells CNE-1, CNE-2. METHODS: We have chosen NPC cell line CNE-2 for the study, and the cells were treated with PA before the detection. CCK-8 assay was used to detect the proliferative ability, and Annexin V-PI double staining was used for the detection of apoptosis rate; and the nucleus damage was detected by transmission electron microscope, the protein expression of the DNA damage pathway were detected by Western blot...
April 17, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28375672/ultrastructural-characterization-of-the-mitochondria-associated-membranes-abnormalities-in-human-astrocytomas-functional-and-therapeutics-implications
#2
Arismendi-Morillo Gabriel, Castellano-Ramírez Alan, Seyfried Thomas N
Mitochondria-associated membranes (MAMs) are currently considered an intracellular organelle "hot spot" for the intracellular signaling. MAMs are thought to function in cellular energy homeostasis, apoptosis, and calcium signaling. MAM ultrastructure in surgical specimens from human astrocytic neoplasms was studied. Abnormalities in respect to density, length, and width were found. Poorly differentiated glioma like-stem cells deficient in MAM and well-differentiated glioma cells abundant in MAM were observed...
April 4, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28296538/hemolytic-uremic-syndrome-findings-of-post-acute-renal-failure-in-light-and-electron-microscopy
#3
Wiesława Salwa-Żurawska, Jakub Żurawski, Aldona Woźniak, Elżbieta Bortkiewicz, Paweł Burchardt, Przemysław Kwiatkowski, Monika Seget, Piotr Tabaczewski
The blood count test results of six patients (five male adolescents and one female adult) who were diagnosed with the hemolytic-uremic syndrome are presented. Certain diverse lesions and especially, their different intensity, were observed. They were referred to the clinical process and the time from syndrome occurrence to biopsy.
March 15, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28277149/in-vitro-activity-of-a-partially-purified-and-characterized-bark-extract-of-castanea-sativa-mill-enc%C3%A2-against-chlamydia-spp
#4
Valentina Papa, Laura Ginocchietti, Roberta Budriesi, Matteo Micucci, Roberta Costa, Roberta Biondi, Roberto Cevenini, Alberto Chiarini, Rita Aldini, Manuela Donati, Gian Matteo Pollini, Giovanna Cenacchi
Castanea sativa Mill (ENC®), containing tannins against 33 Chlamydia strains, was compared to SMAP-29 with inhibitory effect against C. trachomatis and C. pneumoniae. The ENC® activity against Chlamydia spp. was evaluated determining the lowest concentration to achieve more than half reduction of intact chlamydial inclusions versus controls. ENC® reduced all Chlamydia strains tested at 1 µg/mL, while SMAP-29 induced reductions of C. trachomatis and C. pneumoniae infectivity at 10 µg/mL. A great reduction of C...
March 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28277148/adverse-effects-of-antiretroviral-therapy-on-liver-hepatocytes-and-endothelium-in-hiv-patients-an-ultrastructural-perspective
#5
Sarah Chwiki, Maria Mercedes Campos, Mary E McLaughlin, David E Kleiner, Joseph A Kovacs, Caryn G Morse, Mones S Abu-Asab
Human immunodeficiency virus and antiretroviral therapy (ART) together can be far more detrimental to liver cells than either of the two unaided. However, ultrastructural aspects of the synergistic effects of HIV and ART have been understudied. In a patient cohort receiving ART, this study characterizes ultrastructurally sinusoidal degeneration, hepatocytic aberrations, mitochondrial dysfunction, accumulation of bulky lipid droplets (steatosis), and occlusion of sinusoidal lumina. Mitochondrial dysfunction causes the accumulation of acetyl-CoA which leads to insulin upregulation and resistance, lipid synthesis, and steatosis...
March 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28277147/renal-biopsy-in-patients-with-systemic-lupus-erythematosus-not-just-lupus-glomerulonephritis
#6
David N Howell
Kidney biopsy is a mainstay in the diagnosis and management of renal disease in patients with systemic lupus erythematosus. Though biopsies from patients with lupus typically show various forms of immune complex glomerulonephritis, other pathologies are occasionally encountered, including unusual lupus-related nephropathies, other forms of autoimmune disease, and occasional renal disorders without any direct connection with lupus or autoimmunity. Electron microscopy is a powerful tool for detecting and classifying these unusual conditions, which frequently have important therapeutic and prognostic implications...
March 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28277146/efficacy-of-gold-nanoparticles-against-isoproterenol-induced-acute-myocardial-infarction-in-adult-male-albino-rats
#7
Samah M Ahmed, Shaimaa Ali Abdelrahman, Alaa Elsayed Salama
This study was undertaken to investigate the role of gold nanoparticles (GNPs) of 50 nm diameter on isoproterenol (ISO) induced acute myocardial infarction in adult male albino rats. Forty five adult Wistar male albino rats were equally divided into three groups. Control (group I) was further subdivided into three subgroups. In group II, the rats received ISO subcutaneously at a dose of 100 mg/kg for three days. In group III, rats received ISO as group II and then GNPs (400 μg/kg/day) intravenously for 14 consecutive days...
March 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28272982/role-of-alpha-lipoic-acid-in-ameliorating-cyclosporine-a-induced-pancreatic-injury-in-albino-rats-a-structural-ultrastructural-and-morphometric-study
#8
Hala F Abd-Ellah, Nadia R A Abou-Zeid
The aim of this study was to investigate the effectiveness of alpha-lipoic acid (α-LA) against cyclosporine A (CsA)-induced pancreatic toxicity in rats. Thirty-two male albino rats were divided into four equal groups. Group I treated orally (per os, p.o.) with vehicles and served as control; Group II received α-LA (100 mg/kg b.w. /day, p.o.) for 21 days; Group III received CsA (25 mg/kg b.w./day, p.o.) for 21 days; and Group IV received α-LA 1 hr before oral treatment by CsA for 21 days. Histological examination of the pancreas of CsA-treated rats showed marked changes represented by wide interlobular septae that contained congested blood vessels, cytoplasmic vacuolation of some acinar cells, and distortion of the other cells...
March 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28151076/histological-study-on-the-effect-of-aroclor-1254-on-the-epididymis-of-adult-rats-and-the-role-of-l-name-administration
#9
Nehad F Mazen, Rania A Zidan
INTRODUCTION: Aroclor 1254, a commercial polychlorinated biphenyls (PCBs) mixture, was found to elicit various adverse effects on human health. OBJECTIVES: This study aimed to investigate the structural alterations in the epididymis induced by aroclor 1254, and to assess the possible protective role of L-NAME (NG-Nitro-L arginine methyl ester). MATERIALS AND METHODS: Thirty-five adult male albino rats were divided into three groups: control group (15 rats), equally subdivided into subgroup a; negative control group, subgroup b: received intraperitoneal corn oil (5 ml/kg/day), and subgroup c: received intraperitoneal L-NAME (10 mg/kg/day)...
March 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28107086/interaction-between-lipid-droplets-and-endoplasmic-reticulum-in-human-atherosclerotic-plaques
#10
Ida Perrotta
Lipid droplets (LDs) are intracellular organelles that are found in nearly all cell types, where they serve fundamental roles in lipid metabolism and energy homeostasis. Traditionally considered as simple lipid storage deposits, these dynamic and remarkable organelles have recently been implicated in a number of other cellular functions, ranging from protein storage and degradation to virus replication. Intracellular accumulation of LDs is also a hallmark feature of diverse human diseases including diabetes type II, obesity, hepatosteatosis, cancer, and atherosclerosis...
January 20, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230520/a-quantitative-study-of-the-interstitial-cells-in-renal-allograft-fibrosis
#11
Miguel A Martínez, María P Ortega
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230519/classification-diagnosis-and-pathogenesis-of-rare-heritable-connective-tissue-disorders-the-impact-of-differential-ultrastructural-aberrations-of-dermal-connective-tissue-components
#12
https://www.readbyqxmd.com/read/28230518/pectus-excavatum-first-ultrastructural-findings-of-a-potential-ciliopathy
#13
Christoph Brochhausen, Andreas Mamilos, Salmai Turial, C James Kirkpatrick
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230517/a-study-of-biofilm-on-endotracheal-tubes-in-pediatric-intensive-care-unit
#14
Magda Azmy, Bassant Meligy, Sahar Khairat, Amal Sayed, Dalia K Ismail, Shaimaa Yahia
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230516/ultrastructural-characterization-of-bacillus-anthracis-spores-the-existence-of-two-spores-subpopulations
#15
W Antunes, P Fonseca, J Freitas, I Gomes, C Alonso, A Matos
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230515/feroze-n-ghadially-physician-scientist-1920-2014
#16
John D Shelburne
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230514/brush-or-scratch-which-biopsy-is-superior-for-the-ultrastructural-diagnosis-of-primary-ciliary-dyskinesia-a-retrospective-analysis
#17
Christoph Brochhausen, Andreas Mamilos, C James Kirkpatrick
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230513/feroze-n-ghadially-polymath-extraordinaire
#18
Ruby Ghadially, Peter Marcus
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230512/a-brief-history-of-the-society-for-ultrastructural-pathology
#19
Gary Mierau
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28230511/x-ray-microanalysis-in-the-study-of-cell-viability
#20
Alice Warley
No abstract text is available yet for this article.
January 2017: Ultrastructural Pathology
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