Noah Fine, Abdelahhad Barbour, Kamini Kaura, Kristopher A Kerns, Dandan Chen, Harsh M Trivedi, Juliana Gomez, Amarpreet Sabharwal, Jeffrey S McLean, Richard P Darveau, Michael Glogauer
BACKGROUND: Stannous fluoride dentifrice is well established for its beneficial clinical effects. In this study, we evaluated the effects of stannous fluoride on inflammation and oral microbiome. METHODS: In this randomized, parallel-arm, double-blind, controlled clinical trial, we compared clinical resolution of experimental gingivitis by evaluating bleeding on probing, gingival index, and plaque index between stannous fluoride stabilized with zinc phosphate (test) and sodium fluoride (control) dentifrices...
October 27, 2023: Journal of Periodontology