journal
https://read.qxmd.com/read/37987224/association-of-environmental-polycyclic-aromatic-hydrocarbons-exposure-with-periodontitis-in-nhanes-2009-2014-a-mixtures-approach
#21
JOURNAL ARTICLE
Jinqiu Sun, Feifei Guo, Lin Wang, Fulei Han, Jia Yang, Shengli Gao
BACKGROUND: Polycyclic aromatic hydrocarbons (PAHs) can invade and cause harm to the human body through various pathways, but there is currently little research on the relationship between mixed-PAHs exposure and periodontitis. The purpose of this study was to examine the effects of mixed-urinary PAHs exposure on periodontitis in adults in the United States. METHODS: The cross-sectional study included 2749 subjects selected from the National Health and Nutrition Examination Survey (NHANES) 2009-2014 cycles...
November 21, 2023: Journal of Periodontology
https://read.qxmd.com/read/37986698/association-between-sequelae-of-covid-19-with-periodontal-disease-and-obesity-a-cross-sectional-study
#22
JOURNAL ARTICLE
Maísa Casarin, Francisco Hecktheuer Silva, Ana Flávia Leite Pontes, Betina Dutra Lima, Flavia Q Pirih, Francisco Wilker Mustafa Gomes Muniz
BACKGROUND: To assess the sequelae of coronavirus disease 2019 (COVID-19) and associated factors, such as obesity and periodontitis in adults. METHODS: The study included 128 individuals aged ≥35 years with a history of a diagnosis of COVID-19 through real-time polymerase chain reaction (RT-PCR), from Pelotas, Brazil. Self-report sequelae from COVID-19 were defined as the primary outcome. A questionnaire containing sociodemographic, medical, behavioral and self-report of sequelae of COVID-19 was applied...
November 21, 2023: Journal of Periodontology
https://read.qxmd.com/read/37986691/mediating-role-of-systemic-inflammation-in-the-association-between-heavy-metals-exposure-and-periodontitis-risk
#23
JOURNAL ARTICLE
Mi Du, Ke Deng, Qingqing Cai, Shixian Hu, Yuntao Chen, Shulan Xu, Geerten-Has E Tjakkes, Shaohua Ge, Minghua Ge, An Li
BACKGROUND: This study evaluated the mediating role of systemic inflammation in the association between exposure to heavy metals and periodontitis in a nationwide sample of adults. METHODS: Pooled cross-sectional data from the National Health and Nutrition Examination Survey (NHANES 2009-2014) were used (n = 8993). Periodontitis was defined by a full-mouth examination and classified as no/mild and moderate/severe (mod/sev) groups. Blood and urinary heavy metal levels were investigated, including cadmium (Cd), lead (Pb), and mercury (Hg)...
November 21, 2023: Journal of Periodontology
https://read.qxmd.com/read/37986648/clinical-and-radiographic-evaluation-of-the-use-of-prf-cgf-and-autogenous-bone-in-the-treatment-of-periodontal-intrabony-defects-treatment-of-periodontal-defect-by-using-autologous-products
#24
JOURNAL ARTICLE
Basem Alshujaa, Ahmet Cemil Talmac, Dicle Altindal, Anas Alsafadi, Abdullah Seckin Ertugrul
BACKGROUND: The purpose of this randomized clinical study was to clinically evaluate and compare the efficiencies of platelet-rich fibrin (PRF), concentrated growth factor (CGF) and autogenous bone graft (ABG) in the treatment of intrabony pockets and to assess the alveolar bone gain (AB gain) radiographically (panoramic and CBCT images). METHODS: Eighty intrabony pockets were divided into four groups: ojnly open flap debridement (OFD), OFD+PRF, OFD+CGF and OFD+ABG; each group consisted of 20 defects...
November 20, 2023: Journal of Periodontology
https://read.qxmd.com/read/37932872/extracellular-adenosine-triphosphate-regulates-inflammatory-responses-of-periodontal-ligament-cells
#25
JOURNAL ARTICLE
Maythwe Kyawsoewin, Jeeranan Manokawinchoke, Chutimon Termkwanchareon, Hiroshi Egusa, Thanaphum Osathanon, Phoonsuk Limraksasin
BACKGROUND: Various stimuli, that is, mechanical stresses or inflammation, induce the release of adenosine triphosphate (ATP) by human periodontal ligament cells (HPDLCs). Extracellular adenosine triphosphate (eATP) affects HPDLCs' functions such as immunosuppressive action and inflammatory responses. Lipopolysaccharide (LPS) is the key factor involved in periodontal inflammation. However, the possible correlation and detailed mechanism of inflammation-mediated eATP by LPS and inflammatory cascade formation in HPDLCs is unclarified...
November 6, 2023: Journal of Periodontology
https://read.qxmd.com/read/37921754/superoxide-dismutase-2-scavenges-ros-to-promote-osteogenic-differentiation-of-human-periodontal-ligament-stem-cells-by-regulating-smad3-in-alveolar-bone-defective-rats
#26
JOURNAL ARTICLE
Wei Qiu, Qian Sun, Na Li, Zehao Chen, Hongle Wu, Zhao Chen, Xiaolan Guo, Fuchun Fang
BACKGROUND: Osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) is an essential event in alveolar bone regeneration. Oxidative stress may be the main inhibiting factor of hPDLSC osteogenesis. Superoxide dismutase 2 (SOD2) is a key antioxidant enzyme, but its effect on hPDLSC osteogenic differentiation is unclear. METHODS: Several surface markers were detected by flow cytometry, and the differentiation potential of hPDLSCs was validated by alkaline phosphatase (ALP), Alizarin Red S, and Oil Red O staining...
November 3, 2023: Journal of Periodontology
https://read.qxmd.com/read/37910482/suppression-of-subgingival-bacteria-by-antimicrobial-photodynamic-therapy-using-transgingival-irradiation-a-randomized-clinical-trial
#27
JOURNAL ARTICLE
Jun-Ichiro Hayashi, Kohta Ono, Yuki Iwamura, Yasuyuki Sasaki, Tasuku Ohno, Ryoma Goto, Eisaku Nishida, Genta Yamamoto, Takeshi Kikuchi, Naoya Higuchi, Akio Mitani, Mitsuo Fukuda
BACKGROUND: Antimicrobial photodynamic therapy (aPDT) is an effective method for eradicating bacteria in periodontal therapy. Standard aPDT requires the insertion of a laser tip into a periodontal pocket, in which the direction of irradiation is limited. Therefore, we devised an aPDT method that uses a transgingival near-infrared wavelength and indocyanine green-encapsulated and chitosan-coated nanoparticles as a photosensitizer. METHODS: Forty patients undergoing supportive periodontal therapy, who had a single root tooth with a pocket of 5 mm or deeper, were used as subjects...
November 1, 2023: Journal of Periodontology
https://read.qxmd.com/read/37910464/aggressive-periodontitis-in-southwestern-american-indian-adolescents
#28
JOURNAL ARTICLE
Thomas E Rams, Adolfo Contreras, Jørgen Slots
BACKGROUND: This study determined the prevalence of aggressive (molar-incisor pattern) (Ag/MI) periodontitis and assessed the associated subgingival bacterial-herpesvirus microbiota in Pueblo Indian adolescents in the southwestern United States. METHODS: The study included 240 Pueblo Indian adolescents, aged 13-20 years old, residing in three Rio Grande River villages in New Mexico and the Hopi Pueblo reservation in Arizona. Adolescents with Ag/MI periodontitis or periodontal health provided subgingival samples for culture of bacterial pathogens and for polymerase chain reaction detection of periodontal herpesviruses...
November 1, 2023: Journal of Periodontology
https://read.qxmd.com/read/37885337/effects-of-a-stabilized-stannous-fluoride-dentifrice-on-clinical-immunomodulatory-and-microbial-outcomes-in-a-human-experimental-gingivitis-model
#29
JOURNAL ARTICLE
Noah Fine, Abdelahhad Barbour, Kamini Kaura, Kristopher A Kerns, Dandan Chen, Harsh M Trivedi, Juliana Gomez, Amarpreet Sabharwal, Jeffrey S McLean, Richard P Darveau, Michael Glogauer
BACKGROUND: Stannous fluoride dentifrice is well established for its beneficial clinical effects. In this study, we evaluated the effects of stannous fluoride on inflammation and oral microbiome. METHODS: In this randomized, parallel-arm, double-blind, controlled clinical trial, we compared clinical resolution of experimental gingivitis by evaluating bleeding on probing, gingival index, and plaque index between stannous fluoride stabilized with zinc phosphate (test) and sodium fluoride (control) dentifrices...
October 27, 2023: Journal of Periodontology
https://read.qxmd.com/read/37846763/prevalence-risk-indicators-and-clinical-characteristics-of-peri-implant-mucositis-and-peri-implantitis-for-an-internal-conical-connection-implant-system-a-multicenter-cross-sectional-study
#30
JOURNAL ARTICLE
Karin Apaza-Bedoya, Maria Elisa Galarraga-Vinueza, Bruna Barbosa Correa, Frank Schwarz, Marco Aurélio Bianchini, Cesar Augusto Magalhães Benfatti
BACKGROUND: Peri-implant disease prevalence is associated with a multifactorial etiology and distinct clinical characteristics of inflammation. METHODS: The present study aimed to assess the prevalence of peri-implant diseases, identify related risk indicators, and associate specific clinical characteristics to peri-implant biological complications in the medium term. Peri-implant diseases were classified according to established case criteria. Patients' data, implant and/or prosthetic features, and maintenance records were collected...
October 17, 2023: Journal of Periodontology
https://read.qxmd.com/read/37846761/a-comparison-of-er-cr-ysgg-laser-to-minimally-invasive-surgical-technique-in-the-treatment-of-intrabony-defects-twelve-month-results-of-a-multicenter-randomized-controlled-study
#31
JOURNAL ARTICLE
Donald Clem, Rick Heard, Michael McGuire, E Todd Scheyer, Chris Richardson, Gregory Toback, John C Gunsolley, Nico Geurs
BACKGROUND: The purpose of this publication is to report on the 12-month clinical and radiographic results comparing the surgical use of the Er,Cr:YSGG laser (ERL) and minimally invasive surgical technique (MIST) for the treatment of intrabony defects in subjects with generalized periodontitis stage III, grade B. METHODS: Fifty-three adult subjects (29 females and 24 males; 19-73 years) with 79 intrabony defects were randomized following scaling and root planing (SRP) to receive ERL monotherapy (n = 27) or MIST (n = 26)...
October 17, 2023: Journal of Periodontology
https://read.qxmd.com/read/37846733/comparative-evaluation-of-semaphorin-4d-peptidylarginine-deiminase-2-and-matrix-metalloproteinase-8-levels-of-gingival-crevicular-fluid-in-periodontally-healthy-and-stage-iii-periodontitis-smoker-and-non-smoker-patients-before-and-after-non-surgical-periodontal
#32
JOURNAL ARTICLE
Aishwarya S Ikhar, Rajashri A Kolte, Abhay P Kolte, Prachi R Rathi, Dhanashree G Ghoderao, Rahul N Dahake
BACKGROUND: This study was designed to assess the influence of non-surgical periodontal therapy (NSPT) on gingival crevicular fluid (GCF) levels of semaphorin-4D (SEMA-4D), peptidylarginine deiminase-2 (PAD-2), and matrix metalloproteinase-8 (MMP-8) levels in periodontally healthy, Stage III periodontitis non-smoker and smoker patients. METHODS: Sixty patients were equally divided into three groups, Group I: Periodontally healthy, Group II: Non-smokers with Stage III periodontitis, and Group III: Smokers with Stage III periodontitis...
October 17, 2023: Journal of Periodontology
https://read.qxmd.com/read/37843067/relationship-between-c-reactive-protein-level-and-periodontitis-and-systemic-diseases
#33
JOURNAL ARTICLE
Jung-Hwa Lee, So-Jung Mun
BACKGROUND: Periodontitis affects systemic disease risk, although the relationship thereof in the context of different C-reactive protein (CRP) levels is not clear. This study investigated the association of periodontitis with systemic diseases according to high-sensitivity CRP (hs-CRP) level and sought to identify the risk of systemic diseases in patients with periodontitis. METHODS: We used data from the seventh (2016-2018) Korea National Health and Nutrition Examination Survey...
October 16, 2023: Journal of Periodontology
https://read.qxmd.com/read/37815812/the-associations-of-coffee-consumption-coffee-types-and-caffeine-metabolites-with-periodontitis-results-from-nhanes-2009-2014
#34
JOURNAL ARTICLE
Qiansi Chen, Ruiyang Ge, Yuxuan Wu, Yuying Wu, Han Yang, Yiming Yu, Qingrong Deng, Yu Qiu, Baochang He, Fuhua Yan, Yanfen Li, Fa Chen
BACKGROUND: Coffee is one of the world's most popular beverages and is the main dietary source of caffeine for most people. The various molecular effects of caffeine suggest that it may enhance bone loss. The purpose of the present study was to investigate the relationship of coffee, coffee types, and caffeine metabolites with periodontitis. METHODS: Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2009-2014. Total coffee and different types of coffee consumption were acquired through a 24-h dietary recall...
October 10, 2023: Journal of Periodontology
https://read.qxmd.com/read/37794683/the-effect-of-a-multicomponent-oral-care-regimen-on-gingival-inflammation-a-randomized-controlled-clinical-trial
#35
JOURNAL ARTICLE
Guilherme C L S do Amaral, Mohamed A Hassan, Luciana Saraiva, Laís Y S Nakao, Marinella Holzhausen, Zilson M Malheiros, Bernal Stewart, Giuseppe A Romito, Cristina C Villar
BACKGROUND: Oral care regimens can be explored to improve oral health in patients with gingivitis. This study aimed to evaluate the efficacy of a multicomponent oral care regimen with a dual zinc plus arginine (DZA) toothpaste and cetylpyridinium chloride with zinc lactate (CPC + Zn) mouthwash in reducing gingival bleeding in patients with gingivitis. METHODS: This randomized clinical trial included 94 participants with gingivitis who were randomized into two groups: the DZA/CPC + Zn group, which used a 1450-ppm fluoride toothpaste containing 0...
October 4, 2023: Journal of Periodontology
https://read.qxmd.com/read/37793053/association-between-missing-teeth-number-and-all-cause-and-cardiovascular-mortality-nhanes-1999-2004-and-2009-2014
#36
JOURNAL ARTICLE
Ruming Shen, Shuaijie Chen, Jiayi Shen, Lingchun Lv, Tiemin Wei
BACKGROUND: The association between tooth loss and all-cause and cardiovascular mortality requires further investigation. METHODS: This study included 17993 participants from the National Health and Nutrition Examination Surveys (NHANES) 1999-2004 and 2009-2014. Weighted multivariable Cox proportional hazard models were used to assess the association between tooth loss and all-cause and cardiovascular mortality. Restricted cubic splines (RCS) were incorporated in the models to explore potential nonlinear relationships...
October 4, 2023: Journal of Periodontology
https://read.qxmd.com/read/37793052/association-between-antihyperlipidemic-agents-and-the-risk-of-chronic-periodontitis-in-patients-with-hyperlipidemia-a-population-based-retrospective-cohort-study-in-taiwan
#37
JOURNAL ARTICLE
An-Yi Wang, Guan-Ling Lin, Joseph Jordan Keller, Li-Hsuan Wang
BACKGROUND: The lipid-lowering and anti-inflammatory effects of statins and fibrates may ameliorate periodontitis. Patients with hyperlipidemia tend to have a worse periodontal status. This study assessed the association between the use of statins/fibrates and the incidence of chronic periodontitis in patients with hyperlipidemia in Taiwan. METHODS: This retrospective cohort study enrolled patients newly diagnosed with hyperlipidemia between 2001 and 2012 from the 2000 Longitudinal Generation Tracking Database and followed them for 5 years...
October 4, 2023: Journal of Periodontology
https://read.qxmd.com/read/37789641/comparative-transcriptome-analysis-of-periodontitis-and-peri-implantitis-in-human-subjects
#38
JOURNAL ARTICLE
Jung-Min Oh, Yeongjoo Kim, Hyojae Son, Yun Hak Kim, Hyun-Joo Kim
BACKGROUND: Peri-implantitis is similar to periodontitis, but there are some differences. For the effective control of peri-implantitis, it is necessary to clarify its similarities and differences with periodontitis in terms of gene expression. METHODS: This cross-sectional study included 20 participants (10 healthy subjects and 10 patients with periodontitis and peri-implantitis). Gingival tissue samples (10 healthy, 10 periodontitis, and 10 peri-implantitis tissues) were collected, RNAs were extracted, and RNA sequencing and analysis were performed...
October 3, 2023: Journal of Periodontology
https://read.qxmd.com/read/37787060/local-application-of-gingiva-derived-mesenchymal-stem-cells-on-experimental-periodontitis-in-rats
#39
JOURNAL ARTICLE
Yunus Emre Balaban, Sema Akbaba, Serife Buket Bozkurt, Arda Buyuksungur, E Ece Akgun, Zeynep Burcin Gonen, Hasan Salkin, Aysen Tezcaner, Sema S Hakki
BACKGROUND: Stem cell-based approaches in regenerative periodontal therapy have been used in different experimental models. In this study, the effect of local application of gingival mesenchymal stem cells (GMSC) in fibroin/chitosan oligosaccharide lactate hydrogel (F/COS) on periodontal regeneration was evaluated using experimental periodontitis model in rats. METHODS: Mesenchymal stem cells were isolated from the gingiva of rats and characterized. Viability tests and confocal imaging of GMSC in hydrogels were performed...
October 3, 2023: Journal of Periodontology
https://read.qxmd.com/read/37724702/an-in-vitro-dynamic-bioreactor-model-for-evaluating-antimicrobial-effectiveness-on-periodontal-polymicrobial-biofilms-a-proof-of-concept-study
#40
JOURNAL ARTICLE
Srinivas Sulugodu Ramachandra, Fekade Bruck Sime, Saiyuri Naicker, Pingping Han, Ryan Sb Lee, Steven C Wallis, Jason A Roberts, Sašo Ivanovski
BACKGROUND: The aim of this study was to investigate an in vitro dynamic bioreactor model by evaluating the antimicrobial effect of clinically relevant amoxicillin doses on polymicrobial microcosm biofilms derived from subgingival plaque. METHODS: Biofilms from pooled subgingival plaque were grown for 108  hours in control and experimental dynamic biofilm reactors. Amoxicillin was subsequently infused into the experimental reactor to simulate the pharmacokinetic profile of a standard 500 mg thrice-daily dosing regimen over 5 days and biofilms were assessed by live/dead staining, scanning electron microscopy, and quantitative polymerase chain reaction...
September 19, 2023: Journal of Periodontology
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