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Journal of Periodontology

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https://www.readbyqxmd.com/read/28088874/a-clinical-validation-of-self-reported-periodontitis-among-participants-in-the-black-women-s-health-study
#1
Brenda Heaton, Nicholas B Gordon, Raul I Garcia, Lynn Rosenberg, Sharron Rich, Matthew P Fox, Yvette C Cozier
BACKGROUND: There is a paucity of data on the validity of self-report of periodontal disease in African Americans. The Black Women's Health Study, a US national cohort study of 59,000 Black women followed via mailed questionnaires since 1995, offered the opportunity to clinically validate self-reported periodontitis among a sample of participants. METHODS: Oral health questionnaires were sent to study participants residing in Massachusetts. Respondents living in the Boston metro area were invited for clinical examination...
January 15, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28067105/antimicrobial-effects-of-mastic-extract-against-oral-and-periodontal-pathogens
#2
Stefka Koychev, Henrik Dommisch, Hong Chen, Nicole Pischon
BACKGROUND: Various antimicrobial agents are widely used in the therapy of oral inflammatory diseases. However, their side effects and the appearance of drug resistance justify research on natural antimicrobial agents to target oral pathogens that are safe for the host. In the present study, antimicrobial properties of mastic extract on commensal and pathogenic oral bacteria, as well as its possible cytotoxic effect toward cells of epithelial and mesenchymal origin, were evaluated in comparison to the common antimicrobial agents hydrogen peroxide (H2O2) and chlorhexidine digluconate (CHX)...
January 8, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/27989223/antibacterial-effect-of-synthetic-peptide-lyetxi-and-lyetxi-%C3%AE-cd-association-compound-against-planktonic-and-multispecies-biofilms-of-periodontal-pathogens
#3
Edison Andrés Cruz Olivo, Daniel Santos, Maria Elena de Lima, Vera Lúcia Dos Santos, Rubén Dario Sinisterra, Maria Esperanza Cortés
BACKGROUND: Antimicrobial peptides (AMPs) have shown rapid and potent effect against planktonic bacteria. However, control of periodontophatic biofilms is a challenge even for AMPs. Thus, we evaluated in vitro the antimicrobial activity of synthetic peptide LyeTxI and the association compound LyeTxI/βCD against multispecies biofilms. METHODS: Sensibility to LyeTxI and LyeTxI/βCD was determined for planktonic Gram-negative periodontopathogens. Time-kill kinetic assay was performed at MICs values in all planktonic strains...
December 17, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27989222/pilot-study-on-the-genetic-background-of-an-active-matrix-metalloproteinase-ammp-8-test-in-finnish-adolescents
#4
Anna Maria Heikkinen, Teija Raivisto, Kaisa Kettunen, Leena Kovanen, Jari Haukka, Elmira Pakbaznejad Esmaeili, Jessica Elg, Dirk-Rolf Gieselmann, Nilminie Rathnayake, Hellevi Ruokonen, Taina Tervahartiala, Timo Sorsa
BACKGROUND: In periodontitis, genetics and smoking play important roles in the host immune system response. Our aim was to study whether the genetic background of initial periodontitis and caries could be detected using an active matrix metalloproteinase (aMMP-8) chair-side (Periosafe ®) (#) test in Finnish adolescents. METHODS: Altogether 47 participants gave their approval for oral fluid collection and analysis as well as DNA analyses. An aMMP-8 chair-side test(#) was performed on the participants (adolescents aged 15 to 17), and full-mouth clinical parameters of oral health were assessed including periodontal, oral mucosal and caries status in Eastern Finland in 2014-2015...
December 17, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27982724/the-proteasome-inhibitor-bortezomib-inhibits-inflammatory-response-of-periodontal-ligament-cells-and-ameliorates-experimental-periodontitis-in-rats
#5
Lin Jiang, Jinlin Song, Xiaolei Hu, Hongmei Zhang, Enyi Huang, Yan Zhang, Feng Deng, Xiaomian Wu
BACKGROUND: Periodontitis is a chronic inflammatory disease initiated by bacteria and their virulence factors. Bortezomib (BTZ) is the first proteasome inhibitor for clinical treatment of malignancies. Its anti-cancer activity is accompanied by an anti-inflammatory effect. However, there are few reports about its anti-inflammatory effect and underlying mechanism in periodontal disease, especially on human periodontal ligament cells (hPDLCs), which are considered as a promising cell-based therapy for treating periodontitis...
December 16, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27976596/influence-of-non-impacted-third-molars-on-the-pathologies-of-adjacent-second-molars-a-retrospective-study
#6
Zhi-Bang Li, Hong-Lei Qu, Li-Na Zhou, Bei-Min Tian, Fa-Ming Chen
BACKGROUND: Although the removal of impacted third molars (I-M3s) is common in dental clinics, the decision to retain or remove asymptomatic non-impacted third molars (N-M3s) presents a significant challenge. This study investigated the influence of N-M3s on the pathologies of the adjacent second molars (A-M2s). METHODS: The clinical status of M3s was evaluated, and the presence of distal caries, the external root resorption (ERR) and the alveolar bone loss of A-M2s were assessed by orthopantomograms (OPGs)...
December 15, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27976595/effect-of-non-surgical-periodontal-treatment-on-gingival-crevicular-fluid-and-serum-endocan-vascular-endothelial-growth-factor-a-and-tumor-necrosis-factor-alpha-levels
#7
Çiğdem C Türer, Duygu Durmuş, Umut Ballı, Berrak Güven
BACKGROUND: Periodontitis is a chronic inflammatory disease occurred by the interaction between pathogenic microorganism and the host defense. Endocan is a proteoglycan secreted by endothelial cells under the control of inflammatory cytokines. The aims of the study were to determine serum and gingival crevicular fluid (GCF) endocan levels in periodontal diseases pathogenesis supported with vascular endothelial growth factor (VEGF) and tumor necrosis factor-alpha (TNF-α) levels and to evaluate the correlation between GCF endocan levels, VEGF and TNF-α levels with periodontal pocket depth...
December 15, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27958767/effect-of-a-connective-tissue-graft-in-combination-with-single-flap-approach-in-the-regenerative-treatment-of-intraosseous-defects
#8
Leonardo Trombelli, Anna Simonelli, Luigi Minenna, Giulio Rasperini, Roberto Farina
BACKGROUND: In the attempt to limit the post-surgery increase in buccal gingival recession (bREC), the effect of a connective tissue graft (CTG) when combined with a buccal Single Flap Approach (SFA) in the regenerative treatment of intraosseous defects was evaluated. METHODS: Data related to 30 patients with an intraosseous defect treated with buccal SFA with (SFA+CTG group; n= 15) or without (SFA group; n= 15) the placement of a CTG and regenerative treatment were retrospectively derived at three clinical centers...
December 13, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27958766/association-of-serum-triglyceride-level-and-gemfibrozil-consumption-with-periodontal-status
#9
Ferena Sayar, Nasrin Akhondi, Soltanali Fallah, Amir Abbas Moalemnia, Azra Cheraghi
BACKGROUND: Hyperlipidemia is a major risk factor for cardiovascular diseases. Considering the suggested association between periodontal and cardiovascular diseases, this study sought to assess the association, if any, between serum triglyceride (TG) levels and gemfibrozil consumption with periodontal parameters. METHODS: This cross-sectional study was conducted on 90 participants including 30 individuals with a normal lipid profile (group H), 30 hypertriglyceridemic patients not on medication (group N) and 30 hypertriglyceridemic patients taking gemfibrozil over a three month period (group M)...
December 13, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27958765/treatment-of-non-contained-infrabony-defects-with-enamel-matrix-derivative-alone-or-in-combination-with-a-biphasic-calcium-phosphate-bone-graft-a-12-month-randomized-controlled-clinical-trial
#10
Meritxell Losada, Rodrigo González, Àngels Pujol, Antonio Santos, José Nart
BACKGROUND: The use of Enamel Matrix Derivative (EMD) when dealing with non-contained defects may be limited, as EMD does not maintain a space itself. It has been proposed the use of combined therapy, using a bone graft in combination with EMD to avoid the collapse of the flap into the bony defect during the healing time. Therefore the aim of this study is to evaluate the clinical and radiological healing response of non-contained infrabony defects following treatment with a combination of EMD and Biphasic calcium phosphate (BC) or EMD alone...
December 13, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27885966/er-cr-ysgg-laser-effectively-ablates-single-species-biofilms-on-titanium-disks-without-detectable-surface-damage
#11
Jason M Strever, Jaebum Lee, William Ealick, Mark Peacock, Daniel Shelby, Cristiano Susin, Donald Mettenberg, Ahmed El-Awady, Frederick Rueggeberg, Christopher W Cutler
BACKGROUND: Increasing evidence implicates biofilms, consisting of species such as Porphyromonas gingivalis, in the etiology of peri-implantitis. Multiple approaches to ablate biofilms on failing implants have been proposed, include the use of lasers; most recently the Er,Cr:YSGG laser. The purpose of this study is to establish an in-vitro single-species biofilm model on implant surfaces and determine power settings of the Er,Cr:YSGG laser that remove the biofilm while not causing physical damage to the disk...
November 25, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27885965/the-parameters-that-improve-the-cleaning-efficiency-of-sub-gingival-air-polishing-on-titanium-implant-surfaces-an-in-vitro-study
#12
Ceylin S Tastepe, Xingnan Lin, Marcel Donnet, Daniel Wismeijer, Yuelian Liu
BACKGROUND: The aim was to unravel how the air-polishing behaves on a titanium surface by evaluating the size and the shape of the cleaned area, influence of the different device settings, and pocket depths and cleaning movements. METHODS: 48 titanium SLA surface film-coated discs were treated with an air abrasive system using a subgingival plastic nozzle. Two subgingival models were employed: open-ended (step 1) and defined-size (step 2). In step 1, the most effective parameters were investigated by 5 sec static applications under different settings...
November 25, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27885964/porphyromonas-gingivalis-capsule-mediated-coaggregation-as-a-virulence-factor-in-mixed-infection-with-fusobacterium-nucleatum
#13
David Polak, Oren Ferdman, Yael Houri-Haddad
BACKGROUND: Porphyromonas gingivalis capsule enables evasion from phagocytosis, invasion of keratinocytes and bacterial survival. In mixed infection, the capsule also participates in coaggregation, which may lead to characteristic virulence not present in the mono-infection. The aim of the study was to evaluate the role of P.gingivalis capsule as a virulence factor in co-aggregated mixed infection with Fusobacterium nucleatum. METHODS: Mixed infections containing F...
November 25, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27858556/does-obstructive-sleep-apnea-increase-the-risk-for-periodontal-disease-a-case-control-study
#14
Hikmet Gamsiz-Isik, Esen Kiyan, Zuleyha Bingol, Ulku Baser, Evin Ademoglu, Funda Yalcin
BACKGROUND: A possible association between periodontitis and obstructive sleep apnea (OSA) has been suggested. The aim of this study was to compare periodontitis prevalence between control and OSA patients by assessing clinical periodontal parameters and the levels of gingival crevicular fluid (GCF) interleukin-1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), high-sensitive C-reactive protein (hs-CRP) and serum hs-CRP. METHODS: A case-control study was performed that included 163 individuals: 83 individuals (18 females; 65 males) with OSA and 80 non-OSA individuals (23 females; 57 males) as controls...
November 18, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27858555/the-occurrence-of-progressive-bone-loss-around-the-anodized-surface-implants-and-rbm-implants-a-retrospective-cohort-study
#15
Hee-Chang Kim, Shin-Young Park, Min-Su Han, Yong-Moo Lee, Young Ku, In-Chul Rhyu, Yang-Jo Seol
BACKGROUND: This study was performed to evaluate the occurrence of progressive bone loss around implants with different implant surfaces. METHODS: We retrospectively examined 2,517 implants in 903 patients, including 1,147 anodized-surface implants in 454 patients and 1,370 resorbable blasting media (RBM)-surface implants in 449 patients, which were placed from January 2006 to December 2010. Through regular check-up radiographs and records, the presence of progressive bone loss up to more than 50% of the fixture length was investigated...
November 18, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27858554/narrow-diameter-3-0-mm-versus-standard-diameter-4-0-and-4-5-mm-implants-for-the-splinted-partial-fixed-restoration-of-posterior-jaws-a-5-year-retrospective-cohort-study
#16
Francesco Pieri, Caterina Forlivesi, Ernesto Caselli, Giuseppe Corinaldesi
BACKGROUND: Evidence concerning the predictability of narrow-diameter implants (NDIs) (< 3.3 mm) to restore partially edentulous posterior areas is limited. The aim of this study was to compare the 5-year outcomes of NDIs (3.0 mm) and standard-diameter implants (SDIs) (4.0-4.5 mm) supporting fixed partial dentures (FPDs) in posterior jaws. METHODS: All patients treated with at least two adjacent NDIs or SDIs according to the available bone thickness and with a minimum follow-up of 5 years after placement were invited to undergo a clinical and radiologic examination...
November 18, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27858553/cross-sectional-evaluation-of-periodontal-status-microbiological-and-rheumatoid-parameters-in-a-large-cohort-of-patients-with-rheumatoid-arthritis
#17
Jan Schmickler, Annegret Rupprecht, Susann Patschan, Daniel Patschan, Gerhard A Müller, Rainer Haak, Rainer F Mausberg, Gerhard Schmalz, Tanja Kottmann, Dirk Ziebolz
BACKGROUND: This study evaluates periodontal conditions and microbiological findings and their influence on rheumatological disease parameters in patients with rheumatoid arthritis (RA). METHODS: 168 RA-patients were included. A healthy control group (HC, n=168) was composed according to age, gender and smoking habits. Rheumatological data (duration of illness, DAS28, RF, aCCP, medications) were extracted from patients' records. Dental examination included: dental findings (DMF-T), gingival inflammation (PBI), periodontal status (probing depth [PD], attachment loss [AL])...
November 18, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27858552/fluvastatin-inhibits-osteoclast-differentiation-and-p-gingivalis-lipopolysaccharide-induced-alveolar-bone-erosion-in-mice
#18
Nitin Kumar Pokhrel, Yong-Gun Kim, Jae-Young Kim, Hong-Hee Kim, Youngkyun Lee
BACKGROUND: Statins have been widely used to treat hypercholesterolemia. In addition to the inhibition of cholesterol synthesis, recent reports suggest bone anabolic property of statins. However, little notice has been paid to the direct effect of statins on osteoclastogenesis and bone resorption. METHODS: The effect of fluvastatin on osteoclast differentiation was determined using in vitro culture of mouse bone marrow macrophages (BMMs) in the presence of macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor kappa B ligand (RANKL)...
November 18, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27858551/increased-levels-of-dissolved-titanium-are-associated-with-peri-implantitis-a-case-control-study
#19
Luciana M Safioti, Georgios A Kotsakis, Alex E Pozhitkov, Whasun O Chung, Diane M Daubert
BACKGROUND: Peri-implantitis represents a disruption of the biocompatible interface between the titanium (Ti) dioxide layer of the implant surface and the peri-implant tissues. Increasing preclinical data suggest that the peri-implantitis microbiota not only triggers an inflammatory immune response but also causes electrochemical alterations of the Ti surfaces, i.e. corrosion, that aggravate this inflammatory response. Thus, we hypothesized that there is an association between the dissolution of titanium from dental implants, which suggests corrosion, and peri-implantitis in humans...
November 18, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27834121/demineralized-freeze-dried-bone-allograft-with-amniotic-membrane-in-the-treatment-of-periodontal-intrabony-defects-12-month-randomized-controlled-clinical-trial
#20
Deepthi D Sali, Joann Pauline George
AIM: The goal of randomized controlled clinical study was to compare the clinical and radiological outcomes of the combination of Open flap debridement, Amniotic membrane and Demineralized Freeze Dried bone Allograft with Open flap debridement and Demineralized Freeze Dried bone Allograft alone in the management of periodontal intrabony defects. METHOD: 10 patients with bilaterally similar intrabony defects were selected. Each of the intrabony defects were randomly allocated for control and test groups...
November 11, 2016: Journal of Periodontology
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