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Journal of Periodontology

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https://www.readbyqxmd.com/read/30411353/association-between-helicobacter-pylori-gastritis-and-dental-diseases-a-cross-sectional-hospital-based-study-in-eastern-saudi-arabia
#1
A S Alagl, M Abdelsalam, M El Tantawi, M Madi, R Aljindan, A Alsayyah, J Alhumaid, A M Hussameddin, R M Alsulaiman, A AlQurain
BACKGROUND: There is inconsistent evidence about the association between Helicobacter pylori (H. pylori) and dental diseases with possible effect of environmental factors. OBJECTIVE: The aims of the study were to assess (1) the association between gastric and oral H. pylori colonization and (2) the association between oral colonization of H. pylori and dental diseases. METHODS: A cross sectional study was conducted in King Fahad University hospital in Khobar, Eastern Saudi Arabia in 2017...
November 8, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30397915/cross-sectional-analysis-of-risk-factors-for-subclinical-periodontitis-ammp-8-as-a-potential-indicator-in-initial-periodontitis-in-adolescents
#2
Anna Maria Heikkinen, Ismo T Räisänen, Taina Tervahartiala, Timo Sorsa
BACKGROUND: To find out how different patient-related risk indicators might be associated with the odds of developing subclinical periodontitis in adolescents. METHODS: This cross-sectional study included 252 Finnish individuals aged 15-16, of whom 141 were boys and 111 girls. A specially trained dentist performed clinical examinations: measurements included periodontal indexes (bleeding on probing, visible plaque index, root calculus and probing depth, smoking by pack years, periodontal bacteria (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, Prevotella nigrescens and Treponema denticola) and the potential salivary periodontal biomarkers (active matrix metalloproteinase-8 [aMMP-8], polymorphonuclear leukocyte elastase [PMN elastase], and total protein, albumin, immunoglobulin A, immunoglobulin G, and immunoglobulin M)...
November 5, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30397909/capsular-defective-porphyromonas-gingivalis-mutant-strains-induce-less-alveolar-bone-resorption-than-w50-wild-type-strain-due-to-a-decreased-th1-th17-immune-response-and-less-osteoclast-activity
#3
Gustavo Monasterio, Baltasar Fernández, Francisca Castillo, Carolina Rojas, Emilio A Cafferata, Leticia Rojas, Carla Alvarez, Alejandra Fernández, Marcela Hernández, Denisse Bravo, Rolando Vernal
BACKGROUND: Encapsulation of Porphyromonas gingivalis has been demonstrated as responsible of several host immunological changes, which have been associated with the pathogenesis of periodontitis. Using a murine model of periodontitis and two isogenic non-capsulated mutants of P. gingivalis, this study aimed to analyze whether P. gingivalis encapsulation induces more severe alveolar bone resorption, and whether this bone loss is associated with a Th1 and Th17-pattern of immune response...
November 5, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30395355/outcome-of-early-dental-implant-placement-versus-other-dental-implant-placement-protocols-a-systematic-review-and-meta-analysis
#4
Seyed Hossein Bassir, Karim El Kholy, Chia-Yu Chen, Kyu Ha Lee, Giuseppe Intini
BACKGROUND: The aim of this systematic review and meta-analysis was to compare the clinical efficacy of the early dental implant placement protocol with immediate and delayed dental implant placement protocols. METHODS: An electronic and manual search of literature was made to identify clinical studies comparing early implant placement with immediate or delayed placement. Data from the included studies were pooled and quantitative analyses were performed for the implant outcomes reported as the number of failed implants (primary outcome variable) and for changes in peri-implant marginal bone level, peri-implant probing depth, and peri-implant soft tissue level (secondary outcome variables)...
November 5, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30394523/dose-response-assessment-of-chemically-modified-curcumin-in-experimental-periodontitis
#5
Dayane de Almeida Brandão, Luis Carlos Spolidorio, Francis Johnson, Lorne M Golub, Morgana Rodrigues Guimarães-Stabili, Carlos Rossa
BACKGROUND: CMC2.24, a novel tri-ketonic chemically-modified compound based on natural di-ketonic curcumin, has been shown to reduce bone loss and inflammatory mediators in experimental periodontitis, however, a potential dose-response relation was not determined. The purpose of this study was to assess the effects of different doses of CMC2.24 on inflammation and bone resorption in vivo and also to describe on the effects of CMC2.24 on macrophage response. METHODS: CMC2...
November 5, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30387879/low-temperature-plasma-on-peri-implant-related-biofilm-and-gingival-tissue
#6
Adriana Fp Carreiro, Juliana A Delben, Sarah Guedes, Ericka Jd Silveira, Malvin N Janal, Carlos Eduardo Vergani, Smruti Pushalkar, Simone Duarte
BACKGROUND: Evaluate the effect of Low Temperature Plasma (LTP) on an anaerobic biofilm and on the biological response of an in vitro reconstituted gingival epithelium tissue. METHODS: P. gingivalis W83 biofilm was cultured on titanium discs and reconstituted gingival tissue were submitted to similar treatment conditions. TREATMENTS: LTP1 - plasma treatment for 1 min, LTP3 - plasma treatment for 3 min, CHX - 0.2% chlorhexidine for 1 min, GAS - gas only (no plasma) for 3 min, NEGATIVE - no treatment...
November 2, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30387495/a-novel-bruton-s-tyrosine-kinase-inhibitor-acalabrutinib-suppresses-osteoclast-differentiation-and-p-gingivalis-lipopolysaccharide-induced-alveolar-bone-resorption
#7
Nitin Kumar Pokhrel, Yong-Gun Kim, Hyo Jeong Kim, Hyung Joon Kim, Ji Hye Lee, So-Young Choi, Tae-Geon Kwon, Heon-Jin Lee, Jae-Young Kim, Youngkyun Lee
BACKGROUND: Periodontitis is not only one of the most prevalent inflammatory diseases among adults, but also commonly linked to numerous systemic conditions including cardiovascular diseases, stroke, and diabetes. Although osteoclasts are responsible for the alveolar bone resorption during periodontitis pathogenesis, the development of pharmacological strategies targeting these cells has not been vastly fruitful. METHODS: Bone marrow macrophages were cultured in the presence of macrophage-colony stimulating factor (M-CSF) and receptor activator of nuclear factor κB ligand (RANKL) to examine the direct effect of acalabrutinib on osteoclastogenesis...
November 2, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30387155/periodontitis-as-another-comorbidity-associated-with-psoriasis-a-case-control-study
#8
Victor Silva Mendes, Luís Otávio Miranda Cota, Amanda Almeida Costa, Alcione Maria Soares Dutra Oliveira, Fernando Oliveira Costa
BACKGROUND: The association between periodontitis and immuno-mediated inflammatory diseases has been widely studied and recognized each more over the past few years. The aim of this study was to evaluate the potential association between psoriasis and periodontitis, as well as the influence of risk variables in this association. METHODS: This case-control study included 756 individuals, 397 with psoriasis and 359 controls. A full-mouth periodontal examination was performed, recording therefore plaque index, probing depth, clinical attachment level and, bleeding on probing...
November 2, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30383303/20-years-later-oral-health-related-quality-of-life-and-standard-of-treatment-in-chronic-periodontitis-patients
#9
Nihad El Sayed, Amelie Baeumer, Shirin El Sayed, Lars Wieland, Dorothea Weber, Peter Eickholz, Bernadette Pretzl
BACKGROUND: To assess oral health related quality of life (OHRQoL) after long-term (20 years) periodontal treatment in patients with chronic periodontitis (ChP) and to compare it with the current clinical outcome and oral health status. METHODS: 20 years after therapy, 63 patients were re-examined. The dental and periodontal status and OHRQoL using the Oral Health Impact Profile-G49 (OHIP-G49) were assessed. Descriptive statistics, correlation analysis and tests for differences were calculated...
November 1, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30383298/multiple-sessions-of-antimicrobial-photodynamic-therapy-associated-with-surgical-periodontal-treatment-in-patients-with-chronic-periodontitis
#10
Uislen B Cadore, Marília B L Reis, Sergio H L Martins, Marcos de M Invernici, Arthur B Novaes, Mario Taba, Daniela B Palioto, Michel R Messora, Sergio L S Souza
BACKGROUND: This double-blind randomized controlled clinical trial assessed the efficacy of multiple sessions of antimicrobial photodynamic therapy (aPDT) as an adjunct to surgical periodontal treatment (ST) in patients with severe chronic periodontitis (SCP). MATERIAL AND METHODS: Sixteen patients with SCP were were treated with aPDT+ST (Test Group, TG) or ST only (Control Group, CG), in a split mouth design. aPDT was applied at 0, 2, 7, and 14 postoperative days only in TG...
November 1, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30380152/relationship-between-rheumatoid-arthritis-and-periodontal-disease-in-korean-adults-data-from-the-sixth-korea-national-health-and-nutrition-examination-survey-2013-2015
#11
Eun Seo Jung, Yoon Young Choi, Kyeong Hee Lee
BACKGROUND: This study aimed to investigate the relationship between rheumatoid arthritis and periodontal disease using data from the Sixth Korea National Health and Nutrition Examination Survey (KNHANES, 2013-2015). METHODS: Of 22,948 subjects who participated in KNHANES, 14,264 who were ≥19 years of age and responded to questions pertaining to periodontal disease and rheumatoid arthritis were analyzed. Periodontal status was measured using the Community Periodontal Index...
October 31, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30378773/microrna-146a-negatively-regulates-the-inflammatory-response-to-porphyromonas-gingivialis-in-human-periodontal-ligament-fibroblast-via-traf6-p38-pathway
#12
Lu Tang, Xudong Li, Yuhao Bai, Pengcheng Wang, Ying Zhao
BACKGROUND: Human periodontal ligament fibroblasts (HPDLFs) represent the first line of defense against pathogens in the periodontal tissue. Porphyromonas gingivialis (P. gingivalis) has been known to be most strongly associated with periodontitis. MicroRNA (miR)-146a is involved in the inflammatory regulation of periodontitis. However, the regulatory mechanism of miR-146a on in P. gingivalis-induced inflammation response in HPDLFs was still unclear. OBJECTIVE: The aim of this study was to investigate whether miR-146a plays a key role in P...
October 31, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30367824/association-between-periodontitis-and-spontaneous-abortion-a-case-control-study
#13
Anchana Chanomethaporn, Anek Chayasadom, Nawarat Wara-Aswapati, Kiattisak Kongwattanakul, Waraporn Suwannarong, Kamonchanok Tangwanichgapong, Gunniga Sumanonta, Oranart Matangkasombut, Ananda P Dasanayake, Waranuch Pitiphat
BACKGROUND: Spontaneous abortion, or miscarriage, is a complication of pregnancy which can severely affect women both physically and psychologically. We investigated the associations of periodontitis and periodontopathic bacteria with spontaneous abortion. METHODS: We conducted a matched case-control study in two tertiary hospitals in Khon Kaen, Thailand. Cases were 85 women with spontaneous abortion at < 20 weeks gestation matched to 85 controls on age, gestational age, and hospital...
October 27, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30367741/histological-and-histomorphometric-evaluation-of-hydroxyapatite-based-biomaterials-in-surgically-created-defects-around-implants-in-dogs
#14
Mai S Attia, Hend M Mohammed, Mohammed G Attia, Mohamed A Abd El Hamid, Eatemad A Shoeriabah
AIM: The present study evaluated histologically and histometrically the efficacy of micro-, nano or mixed composite of hydroxyapatite graft in treatment of surgically created defects around dental implants in mongrel dogs. MATERIALS AND METHODS: Immediate implant was used after extraction of lower third premolar in mongreal male dogs. Critical size defects were created in intact proximal alveolar bone to each implant. The defects were divided randomly into four groups of two animals based on biomaterials used for treatment:1 received no treatment (negative control);2 defects treated with nanohydroxyapatite bone graft;3 defects treated with micro hydroxyapatite bone graft; and4 defects treated with a mixed composite of micro and nano hydroxyapatite...
October 27, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30367739/effects-of-methods-of-hydration-of-a-biphasic-ceramic-graft-on-bone-regeneration-of-extraction-socket-defects
#15
Igor Guimarães Barros Paulinelli Santos, Carolina Miler Mattos de Santana, Adriana Therezinha Neves Novelino Alves, Marcelo José Pinheiro Gueded de Uzeda, Mônica Diuana Calasans-Maia, Ronaldo Barcellos de Santana
BACKGROUND: alveolar volumetric changes are inherent to the healing process after tooth extraction and filling of the extraction site with biomaterials can reduce these volumetric changes and provide a more favorable environment for the future prosthetic restoration with implants. Among the biomaterials available, biphasic ceramic compounds have shown promissing clinical results, however, histological evaluation of bone tissue response to different hydration and incorporation methods are limited...
October 27, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30367736/hypermobile-upper-lip-is-highly-prevalent-among-patients-seeking-treatment-for-gummy-smile
#16
Reem I Andijani, Dimitris N Tatakis
BACKGROUND: Excessive gingival display (EGD), or a gummy smile (GS), is a mucogingival deformity that can be of concern to patients. The prevalence of GS etiologies, such as altered passive eruption (APE) and hypermobile upper lip (HUL), has not been reported. The aim of this study was to assess the prevalence of APE and HUL in patients seeking to correct their GS, and to determine possible prevalence differences among patients with different gingival display (GD) levels. MATERIALS AND METHODS: During clinical screening of patients interested to participate in a GS treatment study, GD diagnosis, GD level, and presence of AEP and/or HUL were determined...
October 27, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30367733/ridge-preservation-procedures-revisited-a-randomized-controlled-trial-to-evaluate-dimensional-changes-with-two-different-surgical-protocols
#17
Heather R Hong, Chia-Yu Chen, David M Kim, Eli E Machtei
BACKGROUND: The effect of different surgical techniques for ridge preservation on soft tissue parameters has seldom been investigated. The objective of this study was to compare the effect of two different ridge preservation techniques on soft and hard tissue dimensions. METHODS: Thirty patients requiring tooth extraction were randomly allocated to either control group C (allograft covered with a non-cross-linked collagen membrane with primary closure) or experimental group E (allograft covered with cross-linked collagen membrane left exposed)...
October 27, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30367723/a-comparative-randomized-prospective-two-center-clinical-study-to-evaluate-the-clinical-and-esthetic-outcomes-of-two-different-bone-grafting-techniques-in-early-implant-placement
#18
Jimmy LianPing Mau, Evan Gordin, Jung-Jen Lin, Mark Chun-Jung Chen, Chung-Han Ho, David Cochran
BACKGROUND: Early implant placement combined with simultaneous contour augmentation was able to rebuild stable facial hard-tissue and soft-tissue contours that were esthetically pleasing. The purpose of this study was to evaluate the clinical esthetic outcome, when two different bone grafting materials were utilized. MATERIALS AND METHODS: Forty-eight patients were randomly assigned into two groups. In the control group, autogenous bone was used to cover the exposed implant surface then a layer of deproteinized bovine bone mineral (DBBM) was added...
October 27, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30362568/tlr-activation-inhibits-the-osteogenic-potential-of-human-periodontal-ligament-stem-cells-through-akt-signaling-in-a-myd88-or-trif-dependent-manner
#19
Yunyan Zhu, Qian Li, Yanheng Zhou, Weiran Li
BACKGROUND: This study investigated the effects of Toll like receptors (TLRs) on human periodontal ligament stem cells (hPDLSCs) osteogenic differentiation and the associated mechanisms. METHODS: TLR1, 3, 4, and 6 expression in hPDLSCs was evaluated by real-time RT-PCR and flow cytometry, whereas their functional roles were assessed based on NF-κB activation and proinflammatory cytokine expression. The osteogenic effects of these TLRs were analyzed by alkaline phosphatase (ALP) staining, ALP activity, and alizarin red staining...
October 26, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/30312471/titanium-particles-generated-during-ultrasonic-scaling-of-implants
#20
Stephen K Harrel, Thomas G Wilson, Mirali Pandya, Thomas G H Diekwisch
BACKGROUND: There is growing concern that titanium particles may play a role in peri-implant breakdown. Ultrasonic scalers are routinely used in the debridement of peri-implant lesions. This in vitro study is designed to evaluate if titanium particles are produced when an ultrasonic scaler is used on an implant. METHODS: New sandblasted, large grit, acid etched (SLA) coated implants were subjected to ultrasonic scaling with stainless steel, titanium, and PEEK plastic tips...
October 12, 2018: Journal of Periodontology
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