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Journal of Periodontology

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https://www.readbyqxmd.com/read/28914597/combination-of-ultrasonic-decontamination-soft-tissue-curettage-and-submucosal-air-polishing-with-povidone-iodine-application-for-non-surgical-therapy-of-peri-implantitis-12-months-clinical-outcomes
#1
Jamal M Stein, Christian Hammächer, Sareh Said-Yekta Michael
BACKGROUND: The aim of this study was to evaluate the clinical outcomes of a concept for non-surgical peri-implantitis combining stepwise mechanical debridement measures with adjuvant Povidone-iodine application with and without systemic antibiotics. METHODS: 45 patients with chronic periodontitis comprising 164 screw-typed implants with peri-implantitis were included. Peri-implantitis was defined as radiographic bone loss of >2 mm, probing pocket depth (PD) ≥5 mm with bleeding on probing (BOP)...
September 15, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28914596/obesity-and-periodontitis-an-experimental-study-to-evaluate-the-periodontal-and-systemic-effects-of-the-co-morbidity
#2
Leire Virto, Pilar Cano, Vanesa Jiménez-Ortega, Pilar Fernández-Mateos, Jerián González, Ana Isabel Esquifino, Mariano Sanz
BACKGROUND: Obesity and overweight have been associated with periodontitis. This study aims to evaluate the periodontal and systemic effects of this association in a validated experimental model. METHODS: 28 male Wistar rats were randomly divided in four groups: control group (Con) (fed with standard diet); high-fat diet group (HFD) (fed with a diet containing 35.2% fat); control group with induced periodontitis (Con-Perio) and HFD group with induced periodontitis (HFD-Perio)...
September 15, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28914595/evaluation-of-gingival-crevicular-fluid-and-peri-implant-sulcus-fluid-levels-of-periostin-a-preliminary-report
#3
Abdullah C Akman, Sezen Buyukozdemir Askin, Guliz N Guncu, Rahime M Nohutcu
BACKGROUND: Periostin, a protein present in the alveolar bone and periodontal ligament, related to response to external forces. The aims of this study are; to detect the levels of periostin in peri-implant sulcular fluid (PISF) and gingival crevicular fluid (GCF), and to evaluate the relationship between periostin, ICTP (Pyridinoline cross-linked carboxyterminal telopeptide of type 1 collagen) and CTX (C-terminal crosslinked telopeptide of type 1 collagen) levels and clinical inflammatory symptoms and duration of functional loading...
September 15, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28914594/salivary-neuropeptides-stress-and-periodontitis
#4
Hady Haririan, Oleh Andrukhov, Michael Böttcher, Eleonore Pablik, Gernot Wimmer, Andreas Moritz, Xiaohui Rausch-Fan
BACKGROUND: Scientific evidence for psychological stress as a risk factor for periodontitis is fragmentary relying mostly on either questionnaire-based or biomarker studies. The aim of this study was to investigate Brain Derived Neurotrophic Factor, Substance P, Vasoactive Intestinal Peptide (VIP), Neuropeptide Y (NPY), Calcitonin Gene Related Peptide and Adrenomedullin as well as cortisol in saliva and serum in periodontal health and disease combined with different aspects of stress and possible associations with clinical parameters...
September 15, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28914593/effects-of-local-administration-of-tiludronic-acid-on-experimental-periodontitis-in-diabetic-rats
#5
Nara L T Nunes, Michel R Messora, Luiz Fernando Oliveira, Mario Lisboa, Marina Costa Barcellos Garcia, Rodrigo O C C Rêgo, Arthur Belém Novaes, Sérgio Luís Scombatti de Souza, Edilson Ervolino, Flávia A C Furlaneto
BACKGROUND: Tiludronic acid (TIL) presents antiresorptive and anti-inflammatory properties and it has not been evaluated in the association periodontitis-diabetes mellitus (DM) to date. This study evaluated the effects of local administration of TIL on experimental periodontitis (EP) in rats with streptozotocin-induced DM. METHODS: Thirty-two animals (Rattus norvegicus, albinus, Wistar) were divided into groups DM/C (Control), DM/EP, DM/EP/TIL1 and DM/EP/TIL3. In groups EP, a ligature was placed around mandibular molars (MM)...
September 15, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28914592/effect-of-topically-applied-hyaluronic-acid-on-pain-and-palatal-epithelial-wound-healing-an-examiner-blind-randomized-controlled-clinical-trial
#6
Selin Yıldırım, Hafize Öztürk Özener, Başak Doğan, Bahar Kuru
BACKGROUND: This study aimed to evaluate the effects of two different concentrations of topical hyaluronic-acid on post-operative patient discomfort and wound healing of palatal donor sites following free gingival graft (FGG) surgery. METHODS: Thirty-six patients requiring FGG were randomly assigned into three groups in an examiner-blind, randomized-controlled clinical trial. After harvesting palatal grafts, 0.2% and 0.8% hyaluronic-acid gels were used in the test-1 and -2 groups, respectively...
September 15, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28895779/combination-of-bone-graft-and-resorbable-membrane-for-alveolar-ridge-preservation-a-systematic-review-meta-analysis-and-trial-sequential-analysis
#7
Giuseppe Troiano, Khrystyna Zhurakivska, Lorenzo Lo Muzio, Luigi Laino, Marco Cicciù, Lucio Lo Russo
INTRODUCTION: Alveolar ridge preservation (ARP) techniques are aimed to reduce the resorption after tooth extraction. The combination of a graft material covered with a resorbable membrane represent one of the most common strategies performed in the clinical practice. The aim of this systematic review was to analyse evidence regarding potential benefits of ARP procedures performed with allogenic/xenogenic grafts in combination with a resorbable membrane coverage in comparison to a spontaneous healing...
September 12, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28895778/eosinophil-cationic-protein-and-histamine-production-by-neutrophils-from-periodontitis-patients
#8
David Ribas, M Carmen Fernández-Carranco, Hajji Nabil, Pedro Bobadilla, Javier Monteseirín
BACKGROUND: Periodontitis develops through an inflammatory process caused by an infection at the microbial biofilm, followed by tissue destruction mediated by leucocytes which clinically cause significant destruction of connective tissue and bone. Several elements derived from the bacteria cause the inflammatory response and the release of mediators involved in the destruction of the periodontium. There are number of inflammatory mediators released by leukocytes, mainly neutrophils, upon bacterial challenge...
September 12, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28875823/useful-immunochromatographic-assay-of-calprotectin-in-gingival-crevicular-fluid-for-diagnosis-of-diseased-sites-in-patients-with-periodontal-diseases
#9
Jun-Ichi Kido, Shinya Murakami, Masahiro Kitamura, Manabu Yanagita, Koichi Tabeta, Kazuhisa Yamazaki, Hiromasa Yoshie, Hisashi Watanabe, Yuichi Izumi, Reiko Suda, Matsuo Yamamoto, Hideki Shiba, Tsuyoshi Fujita, Hidemi Kurihara, Mitsuharu Mizuno, Akihiro Mishima, Nobumasa Kawahara, Kazuhiro Hashimoto, Koji Naruishi, Toshihiko Nagata
BACKGROUND: Calprotectin, an inflammation-related protein, is present in gingival crevicular fluid (GCF) and the determination of calprotectin is useful for diagnosing periodontal diseases. We have recently developed a novel immunochromatographic (IC) chip system (SI-101402) to determine calprotectin levels in GCF. In the present study, the usefulness of this diagnostic system was investigated in patients with periodontal diseases. METHODS: Thirty-six patients with periodontal diseases participated in this clinical test at multiple centers...
September 6, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28871892/association-between-asthma-and-periodontal-disease-a-systematic-review-and-meta-analysis
#10
Vittorio Moraschini, José de Albuquerque Calasans-Maia, Monica Diuana Calasans-Maia
BACKGROUND: The aim of this systematic review is to evaluate the association between asthma and periodontal disease. METHODS: An electronic search without date or language restrictions ​​was carried out in MEDLINE, Cochrane, Web of Science, and LILACS until May 2016. In addition, manual search and in the grey literature were also conducted. The search process, data analysis, and quality assessment were performed by two independent reviewing authors. Eligibility criteria included prospective and retrospective cohort studies, case-controls, and randomized clinical trials...
September 5, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28871891/inhibition-of-5-lipoxygenase-5-lo-attenuates-inflammation-and-bone-resorption-in-lipopolysaccharide-lps-induced-periodontal-disease
#11
Debora E M Lopes, Camila L Jabr, Naiara N Dejani, Amanda C Saraiva, Sabrina G de Aquino, Alexandra I Medeiros, Carlos Rossa Junior
BACKGROUND: Arachidonate-5-lipoxygenase (5-LO) activity and increased leukotriene B4 (LTB4) production have been implicated in various inflammatory conditions. Increased production of leukotrienes has been associated with periodontal diseases; however their relative contribution to the tissue destruction is unknown. We used an orally-active specific 5-LO inhibitor to assess its role in inflammation and bone resorption in a murine model of lipopolysaccharide (LPS)-induced periodontal disease...
September 5, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28871890/association-between-periodontitis-with-blood-lipid-levels-in-korean-population
#12
Seyoung Lee, Aejung Im, Eunae Burm, Mina Ha
BACKGROUND: Hyperlipidemia is a known risk factor for cardiovascular diseases. A common biological mechanism between systemic diseases like cardiovascular diseases and periodontal diseases has been suggested. We aimed to examine the association between blood lipid profile and periodontitis. METHODS: The study included 6,905 Korean adults, aged ≥20 years. Individuals with incomplete data on blood lipid levels, those who lacked results of periodontitis examination by using the Community Periodontal Index system in the Fifth Korean National Health and Nutrition Examination Survey for 2010 and 2012, and those diagnosed with diabetes mellitus, hypertension and hyperlipidemia were excluded from the study...
September 5, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28846062/association-of-the-salivary-triggering-receptor-expressed-on-myeloid-cells-its-ligand-peptidoglycan-recognition-protein-1-axis-with-oral-inflammation-kidney-disease
#13
Karita M Nylund, Hellevi Ruokonen, Timo Sorsa, Anna Maria Heikkinen, Jukka H Meurman, Fernanda Ortiz, Taina Tervahartiala, Jussi Furuholm, Nagihan Bostanci
BACKGROUND: Triggering Receptor Expressed on Myeloid Cells (TREM-1) is a cell-surface receptor involved in amplification of inflammatory response to bacterial infections, along with its ligand peptidoglycan recognition protein 1 (PGLYRP1). TREM-1 is shed by matrix metalloproteinases (MMPs) to its soluble (s) form. The aim of the study was to investigate association of sTREM-1 and PGLYRP1 with oral inflammatory burden among chronic kidney disease (CKD) patients at predialysis and post-transplantation stages...
August 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28844191/microbiological-response-to-periodontal-therapy-and-multivariable-prediction-of-clinical-outcome
#14
Andrea Mombelli, Adnan Almaghlouth, Norbert Cionca, José Cancela, Delphine S Courvoisier, Catherine Giannopoulou
BACKGROUND: This study assessed the microbiological effects of a 2-phase antimicrobial periodontal therapy and tested microbiological, clinical, and biological markers as prognostic indicators for clinical success. METHODS: Eighty patients with chronic or aggressive periodontitis received periodontal treatment supplemented with 375 mg amoxicillin plus 500 mg metronidazole, 3/d for 7 days. In group A the antibiotics were given during the first, non-surgical (T1), in group B during the second, surgical, phase (T2)...
August 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28844190/smoking-may-lead-to-marginal-bone-loss-around-non-submerged-implant-during-bone-healing-by-altering-salivary-microbiome-a-prospective-study
#15
Xiaobo Duan, Tingxi Wu, Xin Xu, Demeng Chen, Anchun Mo, Yiling Lei, Lei Cheng, Yi Man, Xuedong Zhou, Yongyue Wang, Quan Yuan
BACKGROUND: This prospective and controlled study elucidates the impact of smoking on salivary microbiome and its further influence on marginal bone loss around the implant during a 3-month bone healing. METHODS: The saliva samples were collected preoperatively from 20 periodontally healthy patients with single-tooth replacement in posterior mandible jaw: smokers (n=10) and non-smokers (n=10). MiSeq sequencing of 16S rRNA gene amplicons was used to characterize the salivary microbiome...
August 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28844189/prevalence-of-comorbidities-in-periodontitis-patients-compared-to-the-general-austrian-population
#16
Martina Sperr, Michael Kundi, Vernes Tursic, Margit Bristela, Andreas Moritz, Oleh Andrukhov, Xiaohui Rausch-Fan, Wolfgang R Sperr
BACKGROUND: To analyze the prevalence and impact of comorbidities in patients with periodontitis in Austria. METHODS: The prevalence of comorbidities was evaluated in 1199 patients with periodontitis (median age: 49, range: 14-83 years). These data were compared to an age and sex matched randomly selected cohort of the Austrian population by an unconditional logistic regression model. RESULTS: Comorbidities were found in 821/1199=68.5% patients...
August 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28844188/transcriptome-of-healthy-gingival-tissue-from-edentulous-sites-in-patients-with-a-history-of-aggressive-periodontitis
#17
Tiago Taiete, Renato Corrêa Viana Casarin, Karina Gonzales Silvério Ruiz, Francisco Humberto Nociti Júnior, Enilson Antônio Sallum, Marcio Zaffalon Casati
BACKGROUND: This study evaluated the transcriptome of healthy gingival tissue from edentulous sites in patients with a history of generalized aggressive periodontitis (GAgP), chronic periodontitis (CP) and in patients with no history of periodontitis (H), using microarray and quantitative reverse transcription polymerase chain reaction (qRT-PCR) analysis. METHODS: Healthy gingival tissue from edentulous sites was taken from GAgP (n =12), CP (n=12) and H (n=12) patients...
August 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28844187/evaluation-of-oxidative-status-in-patients-with-chronic-periodontitis-and-polycystic-ovary-syndrome-a-cross-sectional-study
#18
Ebru Saglam, Cenk Fatih Canakcı, Saime Ozbek Sebin, Nesrin Saruhan, Metin Ingec, Hümeyra Canakcı, Ufuk Sezer
BACKGROUND: The aim of the present study was to investigate the salivary and serum 8-hydroxy-2´-deoxyguanosine (8-OHdG) and malondialdehyde (MDA) levels as well as total antioxidant status (TAS), in females with chronic periodontitis (CP) and polycystic ovary syndrome (PCOS), compared to healthy females. METHODS: Four groups, each consisting of 22 individuals, respectively women with both PCOS and CP (PCOSCP), systemically healthy women with CP (CP), periodontally healthy women with PCOS (PCOSPH) and periodontally and systemically healthy women (PH)...
August 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28820323/non-surgical-model-for-alveolar-bone-regeneration-by-bone-morphogenetic-protein-2-7-gene-therapy
#19
Mariko Kawai, Yo-Hei Kataoka, Junya Sonobe, Hiromitsu Yamamoto, Masakazu Inubushi, Takuya Ishimoto, Takayoshi Nakano, Hiroki Maruyama, Jun-Ichi Miyazaki, Toshio Yamamoto, Kazuhisa Bessho, Kiyoshi Ohura
BACKGROUND: Alveolar bone is a critical tissue for tooth retention; however, once alveolar bone is lost, it may not spontaneously regenerate. Currently, bone grafts or artificial bone are commonly used for alveolar bone regeneration therapy. However, these therapies require surgical procedures, which present risks, particularly in aged patients. Therefore, the development of alveolar bone regeneration techniques that do not require surgical procedures is critical. It is well known that stem cells present in the periosteal and periodontal ligament may be induced to differentiate into osteogenic cells...
August 18, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28820322/platelet-rich-fibrin-prf-in-regeneration-of-intrabony-defects-a-randomized-controlled-trial
#20
Gauresh Kumar Patel, Sheela Kumar Gujjari, Veerendra Kumar S C
BACKGROUND AND OBJECTIVE: Platelet-rich fibrin (PRF) is a autologous non transfusional hemo-component with a high concentration of platelets. It incorporates leukocytes, platelets and growth factors within the dense fibrin matrix and can be used as healing biomaterial. This study assessed the adjunctive use of PRF in regenerative management of intrabony defects in comparison with open flap debridement. METHODOLOGY: 26 bilateral defects (13 per group) in 13 patients were randomized as either PRF (Test group) or Open flap debridement alone (control group) sites...
August 18, 2017: Journal of Periodontology
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