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Journal of Periodontology

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https://www.readbyqxmd.com/read/28708039/comparison-of-endothelial-function-in-healthy-chronic-periodontitis-and-myocardial-infarction-patients
#1
Anahita Punj, Santhosh B Shenoy, Subramanyam K
BACKGROUND: The inflammatory burden as a result of severe periodontal disease acts as an insult to the endothelium. This disruption in the function of the endothelium, predisposes it towards formation of atherosclerotic plaque, which may be a subsequent risk for coronary artery disease. The aim of this study was to estimate and compare endothelial function via flow mediated dilation (FMD) assessment in periodontal health and disease. MATERIAL AND METHODS: A total of 120 patients were selected and categorized equally into three groups of healthy, chronic periodontitis and myocardial infarction patients...
July 14, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28708038/influence-of-implant-neck-surface-and-placement-depth-on-crestal-bone-changes-around-platform-switched-implants-a-clinical-and-radiographic-study-in-dogs
#2
Cristina Valles, Xavier Rodríguez-Ciurana, Jose Nart, Antonio Santos, Marta Galofre, Dennis Tarnow
OBJECTIVES: The aim of this animal study was to analyze bone remodeling around platform-switching (PS) implants with and without a machined collar placed at different levels in relation to crestal bone in a canine model. MATERIAL AND METHODS: All mandibular premolars and the first molars were extracted in five dogs. At 6 months, six PS implants with and without a machined neck (MACH and GBAE implants, respectively) were randomly inserted in each hemimandible positioning the implant-abutment interface in either a supracrestal (+1...
July 14, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28708037/greater-sensitivity-of-oral-fibroblasts-to-smoked-vs-smokeless-tobacco
#3
Thomas E Lallier, John T Moylan, Erin Maturin
OBJECTIVE: Smokers have an increased incidence and severity of periodontal disease. While cigarette smoke contains over 4,000 chemical components that could affect periodontal tissues, less is understood about the effect of smokeless tobacco. Therefore, this study compared the effects of cigarette smoke extract (CSE) to smokeless tobacco extract (STE) on cell survival and motility of periodontal ligament (PDL) and gingival fibroblasts in vitro. METHODS: PDL and gingival fibroblasts were exposed to varying concentrations of CSE, STE or nicotine alone...
July 14, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28691888/extracellular-signal-regulated-protein-kinases-protein-kinase-b-p53-bh3-interacting-domain-death-agonist-pathway-regulates-gingipain-induced-apoptosis-in-osteoblasts
#4
Fuping Zhang, Qihong Qiu, Xiangchen Song, Yuting Chen, Juan Wu, Min Liang
BACKGROUND: Gingipains are cysteine proteases produced by Porphyromonas gingivalis, the predominant pathogen in chronic periodontitis. The present study aimed to examine the role of gingipains in promoting apoptosis in osteoblasts. METHODS: Human calvarial osteoblasts and osteoblast MC3T3-E1 cells were treated with 8.348 U/L gingipains. Flow cytometry analysis and terminal deoxynucleotidyl transferase (TdT)-mediated deoxy-UTP nick end labeling (TUNEL) staining were used to detect cell apoptosis...
July 10, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28691887/effects-of-an-erbium-yttrium-aluminum-garnet-er-yag-laser-and-an-ultrasonic-scaler-on-tio2-coated-titanium-surfaces-contaminated-with-subgingival-plaque-an-in-vitro-study-to-assess-post-treatment-biocompatibility-to-osteogenic-cells
#5
Marco Giannelli, Daniele Bani, Alessia Tani, Fabrizio Materassi, Flaminia Chellini, Chiara Sassoli
BACKGROUND: We evaluated the effects of conventional ultrasonic scaler vs. Er-YAG laser on titanium surfaces contaminated with subgingival plaque from peri-implantitis patients in terms of: plaque and bio-corroded titanium oxide coating removal; surface change induction; residual biocompatibility towards osteoblasts. METHODS: Subgingival plaque-coated titanium discs with moderately rough surface were fixed with ethanol and treated with ultrasonic scaler (metal tip) or Er-YAG laser (20...
July 10, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28691886/salivary-levels-of-nlrp3-inflammasome-related-proteins-as-potential-biomarkers-of-periodontal-clinical-status
#6
Diana M Isaza-Guzmán, Verónica M Medina-Piedrahíta, Carolina Gutiérrez-Henao, Sergio I Tobón-Arroyave
BACKGROUND: Emerging evidence suggests that the activation of inflammasomes plays a central mechanism in the pathogenesis of periodontitis. This study aimed to compare the salivary levels of nod-like receptor family pyrin domain containing protein 3 (NLRP3), apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), cysteine aspartase-1 (caspase-1), and interleukin-1 beta (IL-1β) from individuals with aggressive (AgP) or chronic periodontitis (CP) and healthy controls (HC), as well as elucidate its association with the periodontal clinical status...
July 10, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28671509/periodontitis-prevalence-and-severity-in-adults-a-cross-sectional-study-in-norwegian-circumpolar-communities
#7
Gro Eirin Holde, Nils Oscarson, Tordis A Trovik, Anders Tillberg, Birgitta Jönsson
BACKGROUND: The aim of this study was to describe the prevalence, severity and extent of periodontitis in the adult population of circumpolar communities in Norway using data from the study Tromstannen - Oral Health in Northern Norway. METHODS: In this cross-sectional survey, data were collected from a randomized population sample (20-79 years) in Northern Norway. Periodontal conditions were assessed for 1,911 dentate adults with a full-mouth periodontal examination...
July 3, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28671508/investigation-of-a-novel-predictive-biomarker-profile-for-the-outcome-of-periodontal-treatment
#8
Sarhang S Gul, Gareth S Griffiths, Graham P Stafford, Mohammed I Al-Zubidi, Andrew Rawlinson, Charles W I Douglas
BACKGROUND: An ability to predict the response to conventional non-surgical treatment of a periodontal site would be advantageous. However, so far the biomarkers or tests devised to achieve this have lacked sensitivity. The aim of this study was to assess the ability of a novel combination of biomarkers to predict the outcome of treatment of patients with chronic periodontitis. METHODS: GCF and subgingival plaque were collected from 77 patients at 3 representative sites, 1 healthy (≤ 3mm) and 2 diseased (≥ 6mm) at baseline and at 3 and 6-months post treatment...
July 3, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28671507/clarithromycin-as-an-adjunct-to-one-stage-full-mouth-ultrasonic-periodontal-debridement-in-generalized-aggressive-periodontitis-a-randomized-controlled-clinical-trial
#9
Naira Maria Rebelatto Bechara Andere, Nídia Cristina Castro Dos Santos, Cássia Fernandes Araujo, Ingrid Fernandes Mathias, Tiago Taiete, Renato Corrêa Viana Casarin, Maria Aparecida Neves Jardini, Luciana M Shaddox, Mauro Pedrine Santamaria
BACKGROUND: The aim of the present study was to evaluate the periodontal clinical and microbiological responses and the possible adverse effects of clarithromycin combined to periodontal mechanical therapy in the treatment of patients with generalized aggressive periodontitis. METHODS: Forty patients were selected and randomly assigned into two groups: Clarithromycin (CLM, n=20): one-stage full-mouth ultrasonic debridement (FMUD) associated with clarithromycin (500 mg - q12hrs for 3 days); Placebo (Placebo, n=20): FMUD associated with placebo pills...
July 3, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28671506/chronic-periodontal-disease-periodontal-pathogen-colonization-and-an-increased-risk-of-precancerous-gastric-lesions
#10
Jinghua Sun, Min Zhou, Christian R Salazar, Rosemary Hays, Sukhleen Bedi, Yu Chen, Yihong Li
BACKGROUND: The present study assessed the association between periodontal pathogen colonization and the potential risk of developing precancerous lesions of gastric cancer (PLGC) in a clinical setting. METHODS: The present study included 35 newly diagnosed patients with PLGC and 70 age-matched individuals without PLGC. A full-mouth intra-oral examination was performed to assess the periodontal conditions. Stimulated whole saliva and pooled plaque samples were collected to evaluate colonization by Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia and Actinobacillus actinomycetemcomitans and to characterize the oral microbial diversity in the saliva and dental plaque...
July 3, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28671505/local-injection-of-hyaluronic-acid-filler-improves-open-gingival-embrasure-validation-through-a-rat-model
#11
Soojin Pi, Yoon Jeong Choi, Soonshin Hwang, Dong-Won Lee, Jong In Yook, Kyung-Ho Kim, Chooryung J Chung
BACKGROUND: Open gingival embrasure, so called the "black triangle", is one of the unsolved dilemmas in adult dentistry. Although various techniques were introduced to improve the black triangles, the lack of reproducible experimental models has prevented the development of successful protocols to regenerate or to compensate the loss of the interdental papilla. Therefore, the objective of this study was first to develop a reliable animal model of open gingival embrasure, and then to validate a minimally invasive injection technique using the hyaluronic acid (HA) filler to augment the interdental papilla...
July 3, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28644108/comparison-of-periodontal-parameters-and-self-perceived-oral-symptoms-among-cigarette-smokers-individuals-vaping-electronic-cigarettes-and-never-smokers-a-pilot-study
#12
Fawad Javed, Tariq Abduljabbar, Fahim Vohra, Hans Malmstrom, Irfan Rahman, Georgios E Romanos
BACKGROUND: There are no studies that have compared periodontal parameters and self-perceived oral symptoms (OS) among cigarette smokers (Group-1), individuals exclusively vaping electronic cigarettes (Group-2) and never-smokers (Group-3). The aim was to assess the periodontal parameters and self-perceived OS among vaping individuals, CS and NS. METHODS: Demographic data, self-perceived OS and duration and daily frequency of vaping and smoking were gathered using a questionnaire...
June 23, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28644107/gingival-perfusion-and-tissue-biomarkers-during-early-healing-of-post-extraction-regenerative-procedures-a-prospective-case-series
#13
Lamees Alssum, Timothy D Eubank, Sashwati Roy, Barbaros S Erdal, Vedat O Yildiz, Dimitris N Tatakis, Binnaz Leblebicioglu
BACKGROUND: Post-extraction alveolar bone loss, mostly affecting the buccal plate, occurs despite regenerative procedures. To better understand possible determinants, this prospective case series assessed gingival blood perfusion and tissue molecular responses in relation to post-extraction regenerative outcomes. METHODS: Adults scheduled to receive bone grafting in maxillary, non-molar, single tooth extraction site were recruited. Clinical documentation included probing pocket depth (PD), keratinized tissue width (KT), tissue biotype (TB), plaque (P) and bleeding...
June 23, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28644106/viability-and-osteogenic-differentiation-of-human-periodontal-ligament-progenitor-cells-are-maintained-after-incubation-with-porphyromonas-gingivalis-protein-extract
#14
Mayra Laino Albiero, Rafael Nóbrega Stipp, Miki Taketomi Saito, Márcio Zaffalon Casati, Enilson Antonio Sallum, Francisco Humberto Nociti, Karina Gonzales Silvério
BACKGROUND: Porphyromonas gingivalis (Pg) is a major periodontal pathogen that contains immunostimulatory components. Periodontal ligament mesenchymal stem cells (PDLSCs) are responsible for regeneration of the periodontium that is lost due to periodontitis. Pathologic factors within the microenvironment that impair resident PDLSCs are not well understood. The present study investigated in vitro the effects of Pg protein extract (PgPE) on the biological properties of CD105-enriched PDL progenitor cell populations (PDL-CD105(+) cells)...
June 23, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28625077/microbiome-and-microbial-biofilm-profiles-of-peri-implantitis-a-systematic-review
#15
Gloria Inés Lafaurie, María Alejandra Sabogal, Diana Marcela Castillo, María Victoria Rincón, Luz Amparo Gómez, Yamil Augusto Lesmes, Leandro Chambrone
BACKGROUND: This systematic review assesses the microbiological profiles of peri-implantitis, periodontitis and healthy implants based on studies that evaluated microbial biofilms and entire microbiomes to establish their similarities and differences. METHODS: The Medical Literature Analysis and Retrieval System Online, via PubMed, EMBASE (Excerpta Medica Database) and Cochrane Central Register of Controlled Trials (CENTRAL) were searched without language restrictions through July 30, 2016...
June 19, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28625076/the-one-abutment-one-time-protocol-a-systematic-review-and-meta-analysis
#16
Momen A Atieh, Andrew Tawse-Smith, Nabeel H M Alsabeeha, Sunyoung Ma, Warwick J Duncan
BACKGROUND: The use of definitive abutments (DAs) at the time of implant placement has been introduced to overcome the limitations of dis/reconnection of healing / provisional abutments (PAs). With little and inconsistent information in the literature regarding the effectiveness of using DAs, the aim of this systematic review was to examine marginal bone and soft tissue level changes, technical and biological complications and implant failure associated with the use of DAs and PAs. METHODS: This systematic review was prepared according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement...
June 19, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28625075/2016-research-forum-poster-session-and-competition-finalists-and-posters
#17
(no author information available yet)
No abstract text is available yet for this article.
June 19, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28598288/implant-patient-compliance-varies-by-periodontal-treatment-history
#18
Blerina Zeza, Andrea Pilloni, Dimitris N Tatakis, Angelo Mariotti, GianLuca Di Tanna, Claudio Mongardini
BACKGROUND: This retrospective study aimed to assess the compliance to supportive periodontal therapy (SPT) of implant treated patients with different periodontitis history and the possible influence of their compliance on peri-implant marginal bone level. MATERIAL AND METHODS: Dental records of 106 patients treated with at least one dental implant were reviewed. A single operator who did not provide care to the patients recorded the following during the first year of implant function (first year of follow-up), during the first 5 years of follow-up and during the entire follow-up duration: (a) number of recalls; (b) compliance, calculated from registered attendance; (c) periodontal disease history; (d) peri-implant radiographic bone level from most recent examination; and (e) clinical parameters: probing pocket depth (PPD) and bleeding on probing (BOP)...
June 9, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28598287/association-between-periodontitis-and-amyloid-%C3%AE-peptide-in-elderly-people-with-and-without-cognitive-impairment
#19
José Antonio Gil-Montoya, Rocío Barrios Rodríguez, Soraya Santana, Inés Sanchez-Lara, Cristobal Carnero Pardo, Francisco Fornieles-Rubio, Juan Montes, Carlos Ramírez, Miguel Angel González-Moles, Javier S Burgos
BACKGROUND: Evidence that periodontal disease is a possible risk factor for cognitive impairment may be explained by the inflammatory hypothesis. The aim of this study was to determine whether periodontitis is related to the amyloid-β (Aβ) load in blood and the role of any such relationship in the association between Aβ and cognitive impairment. MATERIAL AND METHODS: A case-control study was performed in elderly people diagnosed with cognitive impairment with or without dementia (cases) and cognitively healthy elderly people; data were collected on the medical and dental history of participants, and blood samples were drawn to determine Aβ levels using an enzyme-linked immunosorbent assay...
June 9, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28598286/gingival-inflammation-and-salivary-or-serum-granulocyte-secreted-enzymes-in-patients-with-polycystic-ovary-syndrome
#20
Aliye Akcalı, Nagihan Bostanci, Özgun Özçaka, Pınar Gümüş, Banu Öztürk-Ceyhan, Taina Tervahartiala, Heidi Husu, Nurcan Buduneli, Timo Sorsa, Georgios N Belibasakis
BACKGROUND: The objective of this cross-sectional study was to investigate the levels of salivary and serum matrix metalloproteinase-9 (MMP-9), myeloperoxidase (MPO), neutrophil elastase (NE) and MMP-9/tissue inhibitors of metalloproteinase (TIMP-1) ratio in polycystic ovary syndrome (PCOS) patients and systemically healthy controls, in the presence or absence of gingivitis. METHODS: Serum and salivary levels of these biomarkers were evaluated in periodontally healthy women with PCOS (Ph) (n=45); women with PCOS and gingivitis (Pg) (n=35); systemically and periodontally healthy women (Hh) (n=25); systemically healthy women with gingivitis (Hg) (n=20)...
June 9, 2017: Journal of Periodontology
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