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American Journal of Otolaryngology

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https://www.readbyqxmd.com/read/28228242/effect-of-vitamin-d-deficiency-on-the-laryngo-pharyngeal-tract
#1
Abdul-Latif Hamdan, Ghina Fakhri, Ghassan Haddad, Gabriel Dunya, Doja Sarieddine, Bilal Turfe, Georges Tabet, Sami Azar
OBJECTIVE: To investigate the effect of vitamin D deficiency on the laryngopharyngeal tract. STUDY DESIGN: Prospective cohort study. SETTING: Tertiary care center. SUBJECTS AND METHODS: A total of 38 human subjects were prospectively recruited, equally divided into two groups. The Vitamin D deficiency group defined as 25-OH<25ng/dl and the control subjects with normal vitamin D level defined as 25-OH>25ng/dl. The presence and severity of vocal tract symptoms was assessed using the Vocal Tract Discomfort score...
February 13, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28202188/rate-of-regional-nodal-metastases-of-cutaneous-squamous-cell-carcinoma-in-the-immunosuppressed-patient
#2
Eamon J McLaughlin, Lauren Miller, Thuzar M Shin, Joseph F Sobanko, Steven B Cannady, Christopher J Miller, Jason G Newman
PURPOSE: Immunosuppressed solid organ transplant recipients (SOTRs) have an increased risk of developing cutaneous squamous cell carcinomas (cSCCs) with metastatic potential. This study sought to determine the rate of regional lymph node involvement in a large cohort of solid organ transplant patients with cutaneous head and neck squamous cell carcinoma. MATERIALS AND METHODS: A retrospective chart review was performed on solid organ transplant patients with head and neck cutaneous squamous cell carcinoma treated at a tertiary academic medical center from 2005 to 2015...
February 4, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28196713/acellular-dermal-graft-pharyngeal-repair-augmentation-after-laryngectomy
#3
Patrik Pipkorn, Parul Sinha, Joseph Zenga, Evan Graboyes, Bruce H Haughey
PURPOSE: Pharyngocutaneous fistula (PCF) after laryngectomy continues to be a serious complication, especially after radiation. Recruitment of non-radiated tissue into the surgical defect may decrease the risk of fistula. These techniques however have significant morbidity and increases operative time. We hypothesized that using acellular dermal graft to reinforce the pharyngeal closure could decrease the risk of fistula, without the added morbidity of a vascularized flap. METHODS: We performed a retrospective chart review of all patients that underwent a laryngectomy between 2005 and 2015 at an acedemic tertiary referral center...
February 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28169009/role-of-adenoidectomy-in-chronic-nasal-obstruction-after-nasal-steroid-therapy-failure
#4
Peter J Ciolek, Allen Xu, Samantha Anne, Katie Geelan-Hansen
OBJECTIVE: To identify clinical characteristics of pediatric patients that failed nasal steroid therapy for management of chronic nasal obstruction and to evaluate the efficacy of adenoidectomy in this subset of patients. DESIGN: Retrospective chart review. SETTING: Tertiary care academic center. SUBJECTS: Analysis was performed on children that underwent adenoidectomy between 2011 and 2015 for chronic nasal obstruction refractory to nasal steroids...
February 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28169008/relationship-of-medial-versus-superior-vocal-cord-location-of-t1-squamous-cell-carcinoma-with-tumor-recurrence
#5
Uri Alkan, Yuval Nachalon, Aron Popovtzer, Sharon Tzelnick, Dan Yaniv, Jacob Shvero
OBJECTIVE: To determine if the clinical behavior of T1 glottic squamous cell carcinoma varies by its location on the medial free edge or upper aspect of the vocal cords. STUDY DESIGN: Retrospective cohort. SETTING: Single tertiary university-affiliated medical center. SUBJECTS AND METHODS: Clinical, treatment, and outcome data were collected for 104 patients with T1N0M0 glottic squamous cell carcinoma who were treated and followed at our center in 1995-2013...
February 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28162794/corrigendum-to-combined-medial-canthopexy-and-lateral-tarsal-strip-for-floppy-eyelid-syndrome-am-j-otolaryngol-37-2016-240-244
#6
Christopher J Compton, Andrew T Melson, Jeremy D Clark, Taha Z Shipchandler, William R Nunery, H B Harold Lee
No abstract text is available yet for this article.
February 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28185668/effect-of-nebulized-budesonide-on-decreasing-the-recurrence-of-allergic-fungal-rhinosinusitis
#7
Qi Dai, Chen Duan, Quan Liu, Hongmeng Yu
OBJECTIVE: The aim of this study was to evaluate the clinical efficacy and the effects on decreasing the recurrence of AFRS (allergic fungal rhinosinusitis) of a budesonide inhalation suspension delivered via transnasal nebulization to patients following endoscopic sinus surgery. SUBJECTS AND METHODS: Thirty-five patients were recruited into this study. Final diagnoses were reached using Bent and Kuhn's criteria. The eligible patients were randomly divided into two groups: the budesonide transnasal nebulization group (group A) and the topical nasal steroids group (group B)...
February 1, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28173955/nasopharyngeal-adenocarcinoma-a-population-based-analysis
#8
Edward C Kuan, Jose E Alonso, Armin Arshi, Maie A St John
OBJECTIVES/HYPOTHESIS: To describe the incidence and determinants of survival of patients with nasopharyngeal adenocarcinoma between the years of 1973 to 2012 using the Surveillance, Epidemiology, and End Result (SEER) database. STUDY DESIGN: Retrospective cohort study using a national database. METHODS: The SEER registry was utilized to calculate survival trends for patients with nasopharyngeal adenocarcinoma between 1973 and 2012. Patient data was then analyzed with respect to histopathology, age, sex, race, stage, grade, and treatment modalities (surgery and radiation therapy)...
January 31, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28162795/hearing-loss-in-meniere-s-disease
#9
LETTER
Hossein Ghazavi, Leila Asadpour
No abstract text is available yet for this article.
January 31, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28215817/free-dermal-fat-graft-reconstruction-of-the-head-and-neck-an-alternate-reconstructive-option
#10
Adam Honeybrook, Sanjay M Athavale, Sanjeet V Rangarajan, Sarah L Rohde, James L Netterville
OBJECTIVES: Ablative procedures of the head and neck often result in significant facial and cervical irregularities and cosmetic asymmetry. The deformity resulting from ablative procedures of the head and neck is a significant source of cosmetic morbidity and postoperative dissatisfaction. Reconstruction of post-ablative defects in the head and neck can employ a broad range of techniques, ranging from primary closure to free tissue transfer. The free dermal fat graft (FDFG) is one such option and has been used to repair volume defects of varying sizes after common head and neck procedures such as parotidectomy...
January 27, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28139319/paradoxical-vocal-fold-motion-pvfm-in-pediatric-otolaryngology
#11
Blake Smith, Claudio Milstein, Bryan Rolfes, Samantha Anne
INTRODUCTION: Paradoxical vocal fold motion (PVFM) is a condition in which the vocal cords exhibit inappropriate inspiratory adduction, and it has been poorly studied in the pediatric population. METHODS: Pediatric patients diagnosed with PVCM by a pediatric otolaryngologist and doctor of speech pathology from 2008 to 2012 were reviewed. Patients in whom another cause for their respiratory disturbance was eventually identified were excluded. Patient demographics, characteristics, treatment, and outcomes were reviewed...
January 24, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28139321/healthcare-usage-after-uvulopalatopharyngoplasty-impact-of-analgesic-regimen
#12
William S Tierney, Gabriel Gabarain, Alan H Kominsky
OUTCOME OBJECTIVES: 1) Analyze differences in healthcare usage between subjects receiving different perioperative analgesic medications after uvulopalatopharyngoplasty (UPPP) surgery. 2) Comment on the impact of perioperative analgesic medication on length of hospital stay and complications after UPPP. METHODS: A retrospective cohort study of 120 UPPPs conducted by a single surgeon in the past 5years was conducted. Subjects were grouped based on perioperative pain medication regimen into three groups; narcotics alone (n=83), narcotics with gabapentin (n=27), or narcotics with ketorolac tromethamine (n=10)...
January 23, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28139318/cochlear-duct-length-one-size-fits-all
#13
J F Thong, D Low, A Tham, C Liew, T Y Tan, H W Yuen
OBJECTIVE: Recent studies demonstrated the utility of high-resolution computed tomography (HRCT) scans in measuring basal cochlear length and cochlear insertion depths. These studies showed significant variations in the anatomy of the cochlea amongst humans. The aim of our study was to investigate for gender and racial variations in the basal turn length of the human cochlea in an Asian population. METHOD: HRCT temporal bone data from year 1997 till 2012 of patients with normally developed cochleae who reported with otologic disease was obtained...
January 21, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28132727/it-is-important-to-measure-changes-in-the-bone-conduction-threshold-when-evaluating-whether-fgf-2-can-be-used-to-repair-blast-induced-total-or-near-total-tympanic-membrane-perforations
#14
LETTER
https://www.readbyqxmd.com/read/28214024/long-term-outcomes-of-endolymphatic-sac-shunting-with-local-steroids-for-meniere-s-disease
#15
Cameron C Wick, Nauman F Manzoor, Caileigh McKenna, Maroun T Semaan, Cliff A Megerian
OBJECTIVES: To evaluate the long-term efficacy of endolymphatic sac shunt techniques with and without local steroid administration. STUDY DESIGN: Retrospective case series and patient survey. SETTING: Tertiary university hospital. PATIENTS: Meniere's disease (MD) patients that failed medical therapy and subsequently underwent an endolymphatic sac shunt procedure. All patients had definitive or probable MD and at least 18-months of follow-up...
January 20, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28215816/nasal-septal-perforation-secondary-to-systemic-bevacizumab
#16
Mathew Geltzeiler, Toby O Steele
IMPORTANCE: A case of nasal septal perforation secondary to systemic bevacizumab therapy for ovarian cancer is reported. Bevacizumab is a vascular endothelial growth factor A (VEGF-A) inhibitor that is becoming more widely utilized in the oncologic community. There is only one prior report of septal perforation secondary to bevacizumab in the Otolaryngology specific literature. The purpose of this report is: 1) to raise awareness and discuss the literature surrounding the sinonasal complications of bevacizumab and 2) provide workup and treatment recommendations based on the sum of the available literature...
January 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28139320/extended-use-of-perioperative-antibiotics-in-head-and-neck-microvascular-reconstruction
#17
Stefanie Saunders, Stephen Reese, Jimmy Lam, Jacqueline Wulu, Scharkuh Jalisi, Waleed Ezzat
PURPOSE: Many head and neck surgical procedures are considered clean-contaminated wounds and antibiotic prophylaxis is recommended. Despite prophylaxis, the incidence of surgical site infections remains significant - especially in the setting of free tissue transfer. The antibiotic course is often of a longer duration after free tissue transfer than the recommended 24hour post-operatively. Currently, there is no consensus on appropriate antibiotic regimen or duration at this time. This study investigates the outcomes of a 7-day perioperative antibiotic regimen after microvascular reconstruction of the head and neck at our institution...
January 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28132728/cochlear-implantation-in-an-npc-patient-post-irradiation-presenting-with-electrode-array-extrusion-through-the-posterior-canal-wall
#18
Celeste Ann Chua, David Low, Tiong-Yong Tan, Heng-Wai Yuen
No abstract text is available yet for this article.
January 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28132726/cochlear-implantation-for-single-sided-deafness-and-tinnitus-suppression
#19
Jourdan T Holder, Brendan O'Connell, Andrea Hedley-Williams, George Wanna
OBJECTIVE: To quantify the potential effectiveness of cochlear implantation for tinnitus suppression in patients with single-sided deafness using the Tinnitus Handicap Inventory. METHODS: The study included 12 patients with unilateral tinnitus who were undergoing cochlear implantation for single-sided deafness. The Tinnitus Handicap Inventory was administered at the patient's cochlear implant candidacy evaluation appointment prior to implantation and every cochlear implant follow-up appointment, except activation, following implantation...
January 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28131549/cortactin-and-phosphorylated-cortactin-tyr-466-expression-in-temporal-bone-carcinoma
#20
Gino Marioni, Elisabetta Zanoletti, Antonio Mazzoni, Andrea Gianatti, Elisa Valentini, Laura Girasoli, Martina Guariento, Luciano Giacomelli, Alessandro Martini, Stella Blandamura
PURPOSE: Cortactin is a multidomain protein engaged in several cellular mechanisms involving actin assembly and cytoskeletal arrangement. Cortactin overexpression in several malignancies has been associated with increased cell migration, invasion, and metastatic potential. Cortactin needs to be activated by tyrosine or serine/threonine phosphorylation. The role of cortactin and phosphorylated cortactin (residue tyr(466)) was investigated in temporal bone squamous cell carcinoma (TBSCC)...
January 19, 2017: American Journal of Otolaryngology
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