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American Journal of Otolaryngology

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https://www.readbyqxmd.com/read/30621930/is-otitis-media-with-effusion-associated-with-oxidative-stress-evaluation-of-thiol-disulfide-homeostasis
#1
Eda Şimşek, Cemile Koca Bicer, Muhammed Recai Mazlumoğlu, Soner Sertan Kara, Ozcan Erel, Ayşe Çarlıoğlu
BACKGROUND: We evaluated the relationship between otitis media with effusion and thiol/disulfide homeostasis using a novel marker of oxidative stress. METHODS: The study group consisted of 30 patients (mean age 8.33 ± 3.30 years) with bilateral otitis media with effusion admitted to our hospital. The control group consisted of 35 (mean age 7.40 ± 3.97 years) age-, sex-, and body mass index-matched healthy subjects. Thiol/disulfide homeostasis was measured using a newly developed method...
December 27, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30621929/radiotherapy-for-parapharyngeal-space-tumors
#2
REVIEW
William M Mendenhall, Primoz Strojan, Jonathan J Beitler, Johannes A Langendijk, Carlos Suarez, Anne W Lee, Alessandra Rinaldo, Juan P Rodrigo, Robert Smee, Avraham Eisbruch, Louis B Harrison, June Corry, Alfio Ferlito
A wide variety of tumors, both benign and malignant, occur in the parapharyngeal space. Depending on histology and extent, treatment may include surgery and/or radiotherapy (RT). Herein we discuss the role of RT in the management of some of the more commonly encountered neoplasms, including salivary gland tumors, paragangliomas, schwannomas, and soft-tissue sarcomas.
December 21, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30595225/investigating-the-role-of-octamer-binding-transcription-factor-4-oct-4-in-oral-cavity-squamous-cell-carcinoma-a-systematic-review-and-meta-analysis
#3
Vasiliki Gliagias, Michael Wotman, Saori Wendy Herman, Peter Costantino, Dennis Kraus, Tristan Tham
No abstract text is available yet for this article.
December 21, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30594401/free-thyroid-transfer-to-anterolateral-thigh-for-prevention-of-radiation-induced-hypothyroidism-an-initial-experience
#4
Rakesh Katna, Nikhil Kalyani, Akshay Deshpande
AIM: Radiation induced hypothyroidism (RIHT) is one of the commonest late side effects of radiation therapy and is seen in more than half of patients and affects quality of life significantly. We report our initial experience on feasibility of free microvascular transfer of thyroid gland out of radiation field to prevent development of RIHT. MATERIAL AND METHODS: A prospective pilot study was undertaken during August 2017 to May 2018. Six Patients with stage III/IV patients of oral cavity cancers who required wide excision/composite resections with microvascular free flap (ALT) reconstruction and adjuvant radiation therapy were enrolled...
December 21, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30594403/bacterial-cellulose-graft-versus-fat-graft-in-closure-of-tympanic-membrane-perforation
#5
REVIEW
Yasser Mohammad Hassan Mandour, Samira Mohammed, M O Abdel Menem
OBJECT: To compare between results of bacterial cellulose graft myringoplasty and fat graft myingoplasty in patients had mild or moderate size safe perforation. METHODS: 120 patients undergoing myringoplasty due to mild or moderate size perforation were divided into 3 groups: group I: 40 patients undergoing myringoplasty with use of bacterial cellulose graft, group II: 40 patients undergoing myringoplasty with use of fat graft, group III: 40 patients undergoing usual myringoplasty with use of temporalis fascia graft (control group)...
December 18, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30594402/the-relationship-between-il-17a-and-il-22-expression-and-clinical-severity-in-patients-with-moderate-severe-persistent-allergic-rhinitis
#6
Shaghayegh Shahsavan, Ashkan Pirayesh, Omid Zargari Samani, Hedayatollah Shirzad, Mohamad Ali Zamani, Soroush Amani, Seyyedeh Maryam Kazemi, Mandana Moghni, Fatemeh Deris, Nader Bageri, Loghman Salimzadeh, Ghadir Tavakoli, Mostafa Gholami Arjenaki
PURPOSE: Several reactions leading to numerous effects are regulated by IL-22. However, the relationship between IL-22 and immunopathogensis of allergic rhinitis (AR) has been rarely investigated. The aim of the present study was to investigate the levels of IL-22 and IL-17A in AR patients and their association with clinical severity of persistent allergic rhinitis (PAR). MATERIALS AND METHODS: Thirty mild persistent allergic rhinitis (M PAR) patients, thirty moderate/severe persistent allergic rhinitis (M/S PAR) patients, and thirty healthy controls were enrolled in this study...
December 18, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30621931/evaluating-the-effect-of-nasal-septoplasty-on-atrial-electromechanical-features
#7
Osman Kayapinar, Adnan Kaya, Cem Ozde, Derya Cebeci, Ilhan Unlu
BACKGROUND: Recent studies have demonstrated that right ventricular (RV) dysfunction and increased pulmonary artery pressure may be frequent in patients with upper airway obstruction. In this study, we evaluated atrial conduction delays in patients with upper airway obstruction secondary to nasal septum deviation (NSD). METHODS: A total of 32 patients with upper airway obstruction secondary to NSD undergoing a septoplasty procedure were enrolled in this study. Preoperative electrocardiography and transthoracic echocardiography were performed in all patients who underwent surgery...
December 15, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30558896/polysomnographic-and-pulmonary-function-changes-in-patients-with-sleep-problems-after-septoplasty-with-turbinectomy
#8
Yasser Mohammad Hassan Mandour, Shaimaa Magdy Abo Youssef, Hany Hussein Moussa
OBJECT: To compare Polysomnography and Pulmonary function tests before and after Septoplasty with Turbinectomy in patients complaining of nasal obstruction and sleep problems due to deviated septum with hypertrophic inferior turbinate. METHODS: 90 patients underwent Septoplasty with Turbinectomy due to nasal obstruction and sleep problems involved in this study, their sleep quality evaluated by polysomnography before and after the surgery, their pulmonary functions assessed by spirometry before and after the operation...
December 11, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30551897/cochlear-implantation-in-patients-with-ossified-cochleas
#9
Tao Yan, Fangru Zong, Xiaojie Ma, Xinbo Xu, Weiliang Chen, Zhongyi Song, Xiao Han, Xiaojing Wang, Hanbing Zhang
PURPOSE: The timing of CI for postmeningitic deafness is controversial and differential outcomes have been reported. To review and share our surgical and auditory outcomes. MATERIALS AND METHODS: 17 patients with ossified cochleas who received CI were enrolled. Clinical data including the cause of cochlear ossification, preoperative examination, onset of deafness, age at implantation, surgical findings, and relevant auditory outcomes was analysed. RESULTS: Cochlear ossification was observed in 53% of patients with HRCT, whereas the corresponding value for MRI was 59%...
December 8, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30558897/osteoradionecrosis-of-the-hyoid-bone-complicated-by-pharyngocutaneous-fistula-a-case-report-and-literature-review
#10
Kayvon F Sharif, Fred M Baik, Lauren E Yue, Muhammad Qazi, Margaret Brandwein-Weber, Azita S Khorsandi, Mark L Urken
BACKGROUND: Osteoradionecrosis (ORN) is a well-known complication following irradiation of head and neck malignancies. ORN commonly occurs in the mandible but is rarely reported in the hyoid bone. CASE PRESENTATION: A 76-year-old female with a history of oropharyngeal squamous cell carcinoma presented with pharyngocutaneous fistula 14 years after primary chemoradiation. Imaging showed necrosis of the hyoid bone. She underwent excision of the hyoid to rule out malignancy...
December 7, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30553601/computational-fluid-dynamics-analysis-of-h-uvulopalatopharyngoplasty-in-obstructive-sleep-apnea-syndrome
#11
Lei Zhu, Haibo Liu, Zhongying Fu, Jianmei Yin
PURPOSE: To explore the impact of H-uvulopalatopharyngoplasty (H-UPPP) in obstructive sleep apnea syndrome (OSAS) and gain insights into the potential mechanism underlying improvement by H-UPPP. METHODS: In a cohort of 11 OSAS patients, computational fluid dynamics (CFD) models of the upper airway were obtained using commercial software from computed tomography (CT) datasets before and after H-UPPP. Morphological and numerical parameters were respectively computed and compared during the peak tidal inspiratory flow...
December 6, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30553603/titanium-ossicular-chain-reconstruction-in-single-stage-canal-wall-down-tympanoplasty-for-chronic-otitis-media-with-mucosa-defect
#12
Feng-Ming Gu, Fang-Lu Chi
PURPOSE: To evaluate surgical outcomes for chronic otitis media with mucosa defect underwent titanium ossicular chain reconstruction (OCR) in single stage canal wall down tympanoplasty (CWD). METHODS: A clinical retrospective study was performed on 83 cases of the chronic otitis media with mucosa defect and 123 ears with mucosa integrity according to intraoperative findings that underwent synchronous titanium OCR in single stage CWD form January 2012 to January 2018...
November 28, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30554883/comparative-study-of-epidermal-growth-factor-and-observation-only-on-human-subacute-tympanic-membrane-perforation
#13
Zheng-Cai Lou, Yihan Dong, Zi-Han Lou
OBJECTIVE: To compare the effects of epidermal growth factor (EGF) and observation only on human subacute tympanic membrane perforation (TMP). METHODS: A total of 44 patients with traumatic TMPs >2 months after trauma were divided into an observation group (n = 18) and EGF group (n = 26). Patients in the EGF group underwent direct application of EGF without stripping of the perforation edge. All patients were followed up for at least 6 months. The TMP closure rate, closure time, and hearing gain were evaluated...
November 27, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30554886/quality-of-life-related-to-symptomatic-outcomes-in-patients-with-vestibular-schwannomas-a-canadian-centre-perspective
#14
Andrea L O Hebb, Niki Erjavec, David P Morris, Liam Mulroy, Manohar Bance, Nael Shoman, Simon Walling
Patients with vestibular schwannomas (VS) typically present with hearing loss and tinnitus as well as variable cranial nerve dysfunctions. Surgical resection, stereotactic radiotherapy and/or conservative management employing serial magnetic resonance or computed tomography imaging serve as the main treatment options. Quality of life (QoL) may be impacted by the extent of tumour burden and exacerbated or relieved by treatment. Subjective assessment and quality of life inventories provide valuable information in client centered approaches with important implications for treatment...
November 22, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30554884/submental-flap-for-reconstruction-of-anterior-skull-base-orbital-and-high-facial-defects
#15
Brent A Chang, S Ryan Hall, Brittany E Howard, Gregory S Neel, Carrlene Donald, Devyani Lal, Thomas H Nagel, Richard E Hayden
PURPOSE: Large anterior skull base, orbital, and high facial defects can present a challenging reconstructive problem. Limited data exists in the literature on the use of a submental flap for reconstructing such defects. We aimed to describe the feasibility, success, and advantages of using variations of the submental flap for reconstruction of anterior skull base, orbital, and high facial defects. MATERIALS & METHODS: Outcomes measured included flap method, flap survival, flap size, reconstructive site complications, donor site complications, and length of hospital stay...
November 22, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30553602/oral-core-needle-biopsy-in-the-diagnosis-of-malignant-parapharyngeal-space-tumors
#16
Renhui Chen, Qian Cai, Faya Liang, Peiliang Lin, Ling Chen
OBJECTIVE: To confirm the pre-treatment diagnosis of parapharyngeal space malignancy could aid the treatment plan. METHODS: For patients with suspected malignant parapharyngeal space tumors following preoperative imaging, oral biopsy was conducted for pathological diagnosis with the use of 22-G biopsy needles. RESULTS: A total of 11 patients were enrolled. There were three previously diagnosed cases of head and neck malignancy, and eight cases were newly diagnosed...
November 22, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30553600/molecular-and-immunologic-analysis-of-laryngeal-squamous-cell-carcinoma-in-smokers-and-non-smokers
#17
Ian-James Malm, Lisa M Rooper, Justin A Bishop, Selmin Karatayli Ozgursoy, Alexander T Hillel, Lee M Akst, Simon R Best
BACKGROUND: Laryngeal squamous cell carcinoma (LSCC) is strongly associated with tobacco use, but recent reports suggest an increasing incidence of LSCC in patients without traditional risk factors, suggesting an alternative etiology of tumorigenesis. The purpose of this study is to characterize this non-smoking population and to compare immunohistochemical markers in tumor specimens from non-smokers and smokers with LSCC. METHODS: A retrospective chart review of patients with LSCC at Johns Hopkins Hospital (JHH) was performed...
November 22, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30554885/excision-of-preauricular-sinus-with-abscess-drainage-in-children
#18
Lizhi Wang, Lai Wei, Weili Lu, Ziye Liu, Meiyi Wang, Zhiqiang Wang
PURPOSE: To introduce a feasible approach for excising a preauricular sinus with abscess in children. MATERIALS AND METHODS: Patients under 14 years old with a preauricular sinus abscess and volunteering for surgery were involved in this study. RESULTS: Neither recurrence nor local deformity was found in these patients with a follow-up of 3 to 72 months. CONCLUSIONS: Excising the preauricular sinus with abscess in children is a feasible approach to treatment...
November 16, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30482405/application-of-indocyanine-green-in-the-parathyroid-detection-and-protection-report-of-3-cases
#19
Hao Jin, Jinrui Fan, Jun Yang, Kun Liao, Zhuocheng He, Min Cui
BACKGROUND: It was thought that identifying the parathyroid gland during surgery was difficult for surgeons. It may be critical to locate the parathyroid for surgeons during thyroidectomy or parathyroidectomy due to the significant function of the parathyroid in calcium balance. According to recent reports, intrinsic fluorescence of the parathyroid has been found. There is some evidence to suggest that new equipment can detect the intrinsic fluorescence via imaging technology. In this case reports, a newly-invented intraoperative fluorescence imaging system and indocyanine green dye were applied to detect the parathyroid gland and evaluate the vascularization of parathyroid...
November 7, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/30497698/clinical-features-of-laryngeal-myasthenia-gravis-a-case-series
#20
REVIEW
XiangLi Yang, Lin Niu, ChunWei Yang, Lin Wang, JiXiang Liu, GuoYing He
BACKGROUND: Myasthenia gravis (MG) is an autoimmune disease. Dysarthria, dysphagia, and difficulty swallowing as exclusive initial and primary complaints in MG (laryngeal MG) are rare and seldom reported. METHODS: Here we review and analyze the largest series of laryngeal MG patients. RESULTS: A total of 30 patients with laryngeal MG as primary manifestation were found in 20 case reports/series. Dysarthria was the most frequent primary symptom (14/30), followed by dysphagia (11/30), slurred speech (4/30) and dysphonia (1/30)...
November 5, 2018: American Journal of Otolaryngology
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