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Biological Trace Element Research

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https://www.readbyqxmd.com/read/28324276/the-cytotoxicity-and-genotoxicity-of-particulate-and-soluble-cobalt-in-human-urothelial-cells
#1
Rachel M Speer, Therry The, Hong Xie, Louis Liou, Rosalyn M Adam, John Pierce Wise
Cobalt use is increasing particularly due to its use as one of the primary metals in cobalt-chromium-molybdenum (CoCrMo) metal-on-metal prosthetics. CoCrMo is a high-strength, wear-resistant alloy with reduced risk for prosthetic loosening and device fracture. More than 500,000 people receive hip implants each year in the USA which puts them at potential risk for exposure to metal ions and particles released by the prosthetic implants. Data show cobalt ions released from prosthetics reach the bloodstream and accumulate in the bladder...
March 21, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28321634/a-preliminary-study-about-the-potential-effects-of-heavy-metals-on-the-human-male-reproductive-parameters-in-hiv-infected-population-in-china
#2
Renyan Li, Letian Zhao, Lianbing Li, Zhiwei Hou, Danyan Zhang, Ling Wan, Li Wei, Yuyou Yang, Jing Lv, Mingfu Ma, Yijian Zhu
Due to the inconsistent effects of human immunodeficiency virus (HIV) on the human male reproduction in previous studies and the impacts of environmental exposures, such as heavy metals, on male reproduction receiving little attention in HIV-infected population, the aim of present study was to investigate whether heavy metals have potential effects on reproductive parameters in HIV-infected men. The current study assessed the associations between semen quality or serum hormone and concentration of the three heavy metal toxicants (lead (Pb), cadmium (Cd), and zinc (Zn)) in seminal, urine, and serum, and 50 HIV-infected men were recruited in the present study...
March 20, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28321633/dietary-intake-of-minerals-vitamins-and-trace-elements-among-geriatric-population-in-india
#3
Aakriti Gupta, Preetika Khenduja, Ravindra Mohan Pandey, Hem Chandra Sati, Nighat Yaseen Sofi, Umesh Kapil
The geriatric population is at a high risk of developing deficiencies of essential micronutrients such as minerals, vitamins, and trace elements and their related deficiency signs and symptoms. Scarce data is available on the dietary intake of essential micronutrients among geriatric subjects in India. Hence, to fill the gap in the existing knowledge, a community-based cross-sectional study was conducted during 2015-2016 in District Nainital, Uttarakhand State, India. A total of 255 geriatric subjects were enrolled from 30 clusters (villages) identified by using population proportionate to size sampling methodology...
March 20, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28317078/role-of-selenium-from-different-sources-in-prevention-of-pulmonary-arterial-hypertension-syndrome-in-broiler-chickens
#4
A K Zamani Moghaddam, M H Mehraei Hamzekolaei, F Khajali, H Hassanpour
Pulmonary arterial hypertension (PAH) syndrome in broilers is associated with hypoxia, which prevails at high altitude. Oxidative stress is the pathogenic mechanism underlying PAH. Because selenium is key element in the structure of antioxidant enzymes, we evaluated pulmonary hypertensive responses in broiler chickens fed with diets supplemented with organic or nano-selenium. One hundred forty-four broilers (starting at 5 days old) were fed with (i) control group: birds received a standard diet; (ii) nano-selenium group: birds were fed with basal diet supplemented with nano-selenium at 0...
March 20, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28316042/serum-level-of-zinc-and-copper-in-sudanese-women-with-polycystic-ovarian-syndrome
#5
Manal E Sharif, Isahg Adam, Mohamed A Ahmed, Duria A Rayis, Hamdan Z Hamdan
The study aimed to evaluate the serum level of zinc and copper in women with polycystic ovarian syndrome (PCOS). A case-control study was conducted at Saad Abualila infertility center (Khartoum, Sudan). The cases were women who had a PCOS based on Rotterdam criteria. The controls were infertile women with no evidence of PCOS. The socio-demographic characteristics and medical history data were gathered using questionnaires. Zinc and copper levels were measured using atomic absorption spectrophotometer. While there was no difference in zinc and copper levels between the two groups (50 women in each arm), mean (SD) of body mass index (BMI) was significantly higher in women with PCOS compared to the controls [28...
March 18, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28315119/alterations-of-mg-2-after-hemorrhagic-shock
#6
Mun-Young Lee, Dong Kwon Yang, Shang-Jin Kim
Hemorrhagic shock is generally characterized by hemodynamic instability with cellular hypoxia and diminishing cellular function, resulting from an imbalance between systemic oxygen delivery and consumption and redistribution of fluid and electrolytes. Magnesium (Mg) is the fourth most abundant cation overall and second most abundant intracellular cation in the body and an essential cofactor for the energy production and cellular metabolism. Data for blood total Mg (tMg; free-ionized, protein-bound, and anion-bound forms) and free Mg(2+) levels after a traumatic injury are inconsistent and only limited information is available on hemorrhagic effects on free Mg(2+) as the physiologically active form...
March 17, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28315118/the-reference-intervals-of-hair-trace-element-content-in-hereford-cows-and-heifers-bos-taurus
#7
Sergey A Miroshnikov, Oleg A Zavyalov, Alexey N Frolov, Irina P Bolodurina, Valery V Kalashnikov, Andrei R Grabeklis, Alexey A Tinkov, Anatoly V Skalny
The objective of the present study was to assess hair trace element content in Hereford heifers and cows (Bos taurus) living in South Ural region and calculate the site-specific reference intervals. Hair trace element content in 150 cows and heifers farmed in the Southern Urals of Russia was assessed using inductively coupled plasma mass-spectrometry. Dietary trace element content corresponded to the adequate values as estimated by recommendations of USSR State Agriculture Committee and U.S. National Research Council...
March 17, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28303511/macro-and-microelement-status-in-animal-and-human-hypertension-the-role-of-the-ace-gene-i-d-polymorphism
#8
Olena Pavlyushchik, Viktor Afonin, Svetlana Fatykhava, Polina Shabunya, Viktoryia Sarokina, Aliaksandr Khapaliuk
Genetic factors that predispose to hypertension may contribute to element disturbances observed in hypertensive patients. We tested the hypothesis that the deletion allele of the angiotensin-converting enzyme (ACE) gene is associated with element imbalances in hypertension. The concentrations of elements in genetically predisposed to hypertension rats (SHRs) and their controls (WKY rats) were also examined. ICP-MS was used for elemental analysis of human hair and animal fur. Genotyping was performed by PCR...
March 16, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28285465/a-rat-experimental-study-of-the-relationship-between-fluoride-exposure-and-sensitive-biomarkers
#9
Zhou Zhou, Hongmei Wang, Binghui Zheng, Zhang Han, Yanqing Chen, Yan Ma
Chronic excessive fluoride exposure impairs human health and damages not only the skeletal system and the teeth but also the soft tissues such as the brain, liver, kidneys, pancreas and spinal cord. However, there is limited research regarding the exposure levels and sensitive biomarkers. This study was aimed to establish the relationship between fluoride exposure and sensitive biomarkers. Ninety-six rats were randomly divided into six groups, with each group exposed to 0, 2, 4, 8, 16 and 32 mg NaF/(kg.bw), respectively...
March 12, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28283953/the-effects-of-agaricus-blazei-murill-polysaccharides-on-cadmium-induced-apoptosis-and-the-tlr4-signaling-pathway-of-peripheral-blood-lymphocytes-in-chicken
#10
Wenjing Liu, Ming Ge, Xuequan Hu, Ai Lv, Dexing Ma, Xiaodan Huang, Ruili Zhang
In this study, we investigated the effects of Agaricus blazei Murill polysaccharides (ABP) on cadmium (Cd)-induced apoptosis and the TLR4 signaling pathway of chicken peripheral blood lymphocytes (PBLs). Seven-day-old healthy chickens were randomly divided into four groups, and each group contained 20 males. The cadmium-supplemented diet group (Cd group) was fed daily with full feed that contained 140 mg cadmium chloride (CdCl2)/kg and 0.2 mL saline. The A. blazei Murill polysaccharide diet group (ABP group) was fed daily with full feed with 0...
March 10, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28283952/trace-element-levels-in-scalp-hair-of-school-children-in-shigatse-tibet-an-endemic-area-for-kaschin-beck-disease-kbd
#11
Ya'nan Guo, Hairong Li, Linsheng Yang, Yonghua Li, Binggan Wei, Wuyi Wang, Hongqiang Gong, Min Guo, Cangjue Nima, Shengcheng Zhao, Jing Wang
Kaschin-Beck disease (KBD) is an endemic osteoarthritis, and the etiology is closely related with levels of trace elements in the human body. Currently, it is clear that the selenium (Se) status of children in KBD areas is lower than that in non-KBD areas in the Tibetan Plateau, whereas role of other elements are yet unknown. This study aimed to assess some essential trace elements (Se, Mo, Mn, Zn, Fe, Cu, Co, and Sr) in children using scalp hair as a biomarker, and 157 samples from school children aged 8-14 years old were collected from both KBD and non-KBD areas in Shigatse, Tibet...
March 10, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28283951/relationships-between-element-contents-in-polish-children-s-and-adolescents-hair
#12
Maria Długaszek, Wojciech Skrzeczanowski
Environment, sex, and age are the main factors which determine the elemental composition of hair. The objective of the study is to determine the contents of calcium (Ca), magnesium (Mg), zinc (Zn), copper (Cu), iron (Fe), lead (Pb), and cadmium (Cd) in girls' and boys' hair in five age groups (within 1-19-year range) corresponding to successive human ontogenesis phases as well as to evaluate the relationships between these elements. Quantitative analysis has been carried out using atomic absorption spectrometry (AAS)...
March 10, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28281224/the-effects-of-supplementary-cr3-chromium-iii-propionate-complex-on-the-mineral-status-in-healthy-female-rats
#13
Halina Staniek, Zbigniew Krejpcio
More and more people use food supplements for various reasons, e.g. to prevent mineral deficiency and diseases (e.g. osteoporosis, diabetes, anaemia). Supplements containing Cr(III) are purchased primarily for weight loss and antidiabetic effects. The aim of this study was to evaluate the effects of supplementary Cr3 {chromium(III) propionate complex, [Cr3O(O2CCH2CH3)6(H2O)3]NO3)} on the mineral status in female Wistar rats. The study was carried out on 30 female Wistar rats, divided into five groups (six animals in each): a control group and test groups fed Cr3 supplemented diets with 100, 200, 500 and 1000 mg Cr · kg(-1) diet (equivalent to 10, 20, 50 and 100 mg Cr ·kg(-1) body mass (b...
March 10, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28281223/effects-of-excess-dietary-fluoride-on-serum-biochemical-indices-egg-quality-and-concentrations-of-fluoride-in-soft-organs-eggs-and-serum-of-laying-hens
#14
Liping Miao, Lanlan Li, Mingxing Qi, Minyao Zhou, Nannan Zhang, Xiaoting Zou
This study was conducted to investigate the effects of excess dietary fluoride (F) on serum biochemical indices, egg quality, and concentrations of F in soft tissues, eggs, and serum of laying hens. Commercial laying hens (n = 576, 51 weeks of age) were randomly allotted to 6 treatments with 6 replicates of 16 birds. The basal diets contained fluorine inclusions at a level of 16 mg/kg, and graded sodium fluoride was added to the basal diet to achieve fluorine inclusions, respectively, at a level of 200, 400, 600, 800, and 1000 mg/kg in the experimental diets...
March 9, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28281222/gene-silencing-of-selenoprotein-k-induces-inflammatory-response-and-activates-heat-shock-proteins-expression-in-chicken-myoblasts
#15
Ruifeng Fan, Haidong Yao, Changyu Cao, Xia Zhao, Ahmed Khalid, Jinxin Zhao, Ziwei Zhang, Shiwen Xu
In the present study, specific small interfering RNA (siRNA) for selenoprotein K (Selk) gene was designed and transfected into chicken myoblasts. Then, the expressions of inflammatory factors (including induced nitric oxide synthase [iNOS], nuclear factor-kappa B [NF-κB], heme-oxygenase-1 [HO-1], cyclooxygenase-2 [COX-2], and prostaglandin E synthase [PTGEs]), inflammation-related cytokines (including interleukin [IL]-1β, IL-6, IL-7, IL-8, IL-17, and interferon [IFN]-γ), and heat shock proteins (HSPs) (including HSP27, HSP40, HSP60, HSP70, and HSP90) were examined at 24 and 72 h after transfection...
March 9, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28275931/the-concentration-of-vanadium-in-pathologically-altered-human-kidneys
#16
Aleksandra Wilk, Barbara Wiszniewska, Dagmara Szypulska-Koziarska, Paulina Kaczmarek, Maciej Romanowski, Jacek Różański, Marcin Słojewski, Kazimierz Ciechanowski, Małgorzata Marchelek-Myśliwiec, Elżbieta Kalisińska
Vanadium has a unique and beneficial effect on both humans and animal organisms; however, excessive amount of the above-mentioned metal can cause many alterations in tissues and organs, including the kidneys. The aim of the study was to determine the concentration of vanadium (V) in the kidneys removed from patients due to lesions of various etiologies, including the rejection of the transplanted kidneys. Additionally, we determined the influence of selected biological and environmental factors on the V concentration...
March 9, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28261763/effects-of-selenium-nanoparticles-on-reproductive-performance-of-male-sprague-dawley-rats-at-supranutritional-and-nonlethal-levels
#17
Lujie Liu, Yudan He, Zhiping Xiao, Wenjing Tao, Jia Zhu, Bin Wang, Zixun Liu, Minqi Wang
This research investigated the influence of selenium nanoparticles (SeNPs) on the reproductive performance of male Sprague-Dawley (SD) rats. A suspension of SeNPs was consecutively administered by oral gavage for 2 weeks at supranutritional (0.2, 0.4, or 0.8 mg Se/kg bw) and nonlethal (2.0, 4.0, or 8.0 mg Se/kg bw) levels to male SD rats. The normal control (NC) rats were exposed to physiological saline alone. Biochemical parameters, sperm motility, gene expression of GPx1 and GPx4, and histopathological evaluation of male spermary were measured in this work...
March 6, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28261762/involvement-of-zn-depletion-in-cd-induced-toxicity-on-prenatal-bone-formation-in-rat
#18
Sana Boughammoura, Marouane Chemek, Safa Ben Mimouna, Mohamed Banni, Imed Messaoudi
This study explored the potential toxicity of Cd on the Zn bone depletion in prenatal bone formation. Female rats received either tap water, Cd, Zn, or Cd + Zn in their drinking water during gestation, and some markers of bone formation were studied in their fetuses removed at the 20th day of pregnancy (GD20). Cd exposure induced maternal hypozincemia and Zn depletion in the femur of the fetuses. A striking inhibition of bone formation in fetuses, expressed by decreases in femur length, width, and area, by the shortening of diaphysis, and by a decrease in length and area of distal and proximal proliferative zones, was observed in fetuses from Cd-exposed mothers...
March 6, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28261761/atp5j-and-atp5h-proactive-expression-correlates-with-cardiomyocyte-mitochondrial-dysfunction-induced-by-fluoride
#19
Hong-Wei Wang, Wen-Peng Zhao, Jing Liu, Pan-Pan Tan, Wei-Shun Tian, Bian-Hua Zhou
To investigate the effect of excessive fluoride on the mitochondrial function of cardiomyocytes, 20 healthy male mice were randomly divided into 2 groups of 10, as follows: control group (animals were provided with distilled water) and fluoride group (animals were provided with 150 mg/L F(-) drinking water). Ultrastructure and pathological morphological changes of myocardial tissue were observed under the transmission electron and light microscopes, respectively. The content of hydrolysis ATP enzyme was observed by ATP enzyme staining...
March 6, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28261760/evidence-of-zinc-in-affording-protection-against-x-ray-induced-brain-injury-in-rats
#20
Priyanka Sharma, Neha Singla, D K Dhawan
In the present world, X-rays have been regarded as one of the most efficient tools in medicine, industry and research. On the contrary, extensive human exposure to these rays is responsible for causing detrimental effects on physiological system. The aim of the present study was to investigate the role of zinc (Zn), if any, in mitigating the adverse effects induced by fractionated X-irradiation on rat brain. Female Sprague-Dawley rats weighing 170-200 g were divided into four different groups viz.: (a) normal control, (b) X-irradiated (21Gy), (c) zinc treated (227 mg/L in drinking water) and (d) X-irradiated + zinc treated...
March 6, 2017: Biological Trace Element Research
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