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Biological Trace Element Research

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https://www.readbyqxmd.com/read/29785630/calcium-channels-rho-kinase-protein-kinase-c-and-phospholipase-c-pathways-mediate-mercury-chloride-induced-myometrial-contractions-in-rats
#1
Swati Koli, Atul Prakash, Soumen Choudhury, Rajesh Mandil, Satish K Garg
Adverse effects of mercury on female reproduction are reported; however, its effect on myogenic activity of uterus and mechanism thereof is obscure. Present study was undertaken to unravel the mechanistic pathways of mercuric chloride (HgCl2 )-induced myometrial contraction in rats. Isometric tension in myometrial strips of rats following in vitro exposure to HgCl2 was recorded using data acquisition system-based physiograph. HgCl2 produced concentration-dependent (10 nM-100 μM) uterotonic effect which was significantly (p < 0...
May 21, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29777526/dietary-intake-and-content-of-cu-mn-fe-and-zn-in-selected-cereal-products-marketed-in-poland
#2
Anna Winiarska-Mieczan, Edyta Kowalczuk-Vasilev, Katarzyna Kwiatkowska, Małgorzata Kwiecień, Ewa Baranowska-Wójcik, Bożena Kiczorowska, Renata Klebaniuk, Wioletta Samolińska
This paper aims to verify whether cereal products are a good source of Cu, Mn, Fe, and Zn in the diets of Poles. The study material comprised of 445 cereal products including baked goods, breakfast cereals and groats, pasta, and rice. Products that required culinary treatment (pasta, groats, rice) were boiled in drinking quality water as recommended by the producer. The content of Cu, Mn, Fe, and Zn was determined by using the FAAS method. The average content of microelements in the analyzed products can be represented as Fe (17...
May 18, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29777525/preconcentration-and-determination-of-trace-nickel-and-cobalt-in-milk-based-samples-by-ultrasound-assisted-cloud-point-extraction-coupled-with-flame-atomic-absorption-spectrometry
#3
Nuket Kartal Temel, Kadriye Sertakan, Ramazan Gürkan
In this study, ultrasound-assisted cloud point extraction (UA-CPE) method was developed for the determination of Ni(II) and Co(II) in milk-based products. After extraction and preconcentration, the Ni(II) and Co(II) contents of samples were determined by flame atomic absorption spectrometry (FAAS). After their complexation with hydroxy naphthol blue (HNB) in the presence of cationic surfactant, CTAB at pH 4.0, the Ni(II) and Co(II) were taken within the micellar phase of nonionic surfactant, TX-114. The micellar phase containing the analytes were diluted to a volume of 0...
May 18, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29777524/mercury-involvement-in-neuronal-damage-and-in-neurodegenerative-diseases
#4
REVIEW
Veronica Lanza Cariccio, Annalisa Samà, Placido Bramanti, Emanuela Mazzon
Neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis are characterized by a chronic and selective process of neuronal cell death. Although the causes of neurodegenerative diseases remain still unknown, it is now a well-established idea that more factors, such as genetic, endogenous, and environmental, are involved. Among environmental causes, the accumulation of mercury, a heavy metal considered a toxic agent, was largely studied as a probable factor involved in neurodegenerative disease course...
May 18, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29770951/requirement-of-tgf%C3%AE-signaling-for-effect-of-fluoride-on-osteoblastic-differentiation
#5
Jingmin Zhang, Ningning Jiang, Haolan Yu, Xiuhua Yu, Fengyang Guo, Zhitao Zhao, Hui Xu
Research focused on transforming growth factor β (TGFβ) signaling in osteoblast is gradually increasing, whereas literature is rare in terms of fluorosis. This work aimed to investigate how TGFβ signaling participated in regulation of the osteoblast by different doses of fluoride treatment. Bone marrow stem cells (BMSCs) were developed into osteoblastic cells and exposed to 1, 4, and 16 mg/L F- with and without 10 ng/mL of TGFβ. Cell viability and differentiation state of osteoblast under different settings were measured by means of cell counting kit and analysis of alkaline phosphatase (ALP) activity as well as formation of mineral nodules...
May 16, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29770950/heme-and-non-heme-iron-on-growth-performances-blood-parameters-tissue-mineral-concentration-and-intestinal-morphology-of-weanling-pigs
#6
Zhao Zhuo, Xiaonan Yu, Sisi Li, Shenglin Fang, Jie Feng
This experiment was conducted to evaluate the effects of heme and non-heme iron sources on growth performances, blood parameters, tissue mineral concentration, and intestinal morphology in weanling pigs. At 25 days of age, 32 newly weaned piglets (Duroc × Landrace × Yorkshire; 8.66 ± 0.59 kg) were allocated to one of the following dietary treatments: control group (basal diet with no extra iron addition), FeSO4 group (basal diet + 100 mg Fe/kg as FeSO4 ), Fe-Gly group (basal diet + 100 mg Fe/kg as Fe-Gly), and Heme group (basal diet + 100 mg Fe/kg as Heme)...
May 16, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29770949/selenium-ameliorates-afb-1-induced-excess-apoptosis-in-chicken-splenocytes-through-death-receptor-and-endoplasmic-reticulum-pathways
#7
Jing Fang, Panpan Zhu, Zhuangzhi Yang, Xi Peng, Zhicai Zuo, Hengmin Cui, Ping Ouyang, Gang Shu, Zhengli Chen, Chao Huang, Wentao Liu
Aflatoxin B1 (AFB1 ) can cause hepatotoxicity, genotoxicity, and immunosuppressive effects for a variety of organisms. Selenium (Se), as an essential nutrient element, plays important protective effects against cell apoptosis induced by AFB1 . This research aimed to reveal the ameliorative effects of selenium on AFB1 -induced excess apoptosis in chicken splenocytes through death receptor and endoplasmic reticulum pathways in vivo. Two hundred sixteen neonatal chickens, randomized into four treatments, were fed with basal diet (control treatment), 0...
May 16, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29767280/carnosine-and-histidine-supplementation-blunt-lead-induced-reproductive-toxicity-through-antioxidative-and-mitochondria-dependent-mechanisms
#8
Mohammad Mehdi Ommati, Akram Jamshidzadeh, Reza Heidari, Zilong Sun, Mohammad Javad Zamiri, Forouzan Khodaei, Saeed Mousapour, Fatemeh Ahmadi, Nafiseh Javanmard, Babak Shirazi Yeganeh
Lead (Pb)-induced reproductive toxicity is a well-characterized adverse effect associated with this heavy metal. It has been found that Pb exposure is associated with altered spermatogenesis, increased testicular degeneration, and pathological sperm alterations. On the other hand, it has been reported that Pb-induced reproductive toxicity is associated with increased reactive oxygen species (ROS) formation and diminished antioxidant capacity in the reproductive system. Hence, administration of antioxidants as protective agents might be of value against Pb-induced reproductive toxicity...
May 16, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29756175/zinc-supplementation-ameliorates-diabetic-cataract-through-modulation-of-crystallin-proteins-and-polyol-pathway-in-experimental-rats
#9
Susmita Barman, Krishnapura Srinivasan
Non-enzymatic glycation of lens proteins and elevated polyol pathway in the eye lens have been the characteristic features of a diabetic condition. We have previously reported the benefits of zinc supplementation in reducing hyperglycemia and associated metabolic abnormalities and oxidative stress in diabetic rats. The current study explored whether zinc supplementation protects against cataractogenesis through modulation of glycation of lens proteins, elevated polyol pathway, oxidative stress, and proportion of different heat shock proteins in the eye lens of diabetic rats...
May 13, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29754285/ecological-and-human-health-risk-assessment-of-heavy-metal-content-of-atmospheric-dry-deposition-a-case-study-kermanshah-iran
#10
Soheil Sobhanardakani
The present study was intended to investigate the ecological and human health risk of cobalt, nickel, and vanadium in the atmospheric dry deposition of the Kermanshah city, Iran, in 2015. Totally 54 samples of atmospheric dry deposition were collected from the three regions of the city with different traffic intensity, and after acid digestion of the samples with ultrapure concentrated HNO3 , the total contents of the metals were determined using inductively coupled plasma optical emission spectrometer (ICP-OES)...
May 12, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29754284/determination-of-seasonal-vitamin-and-mineral-contents-of-sea-bream-sparus-aurata-l-1758-cultured-in-net-cages-in-central-black-sea-region
#11
Dilara Kaya Öztürk, Birol Baki, İsmihan Karayücel, Recep Öztürk, Gülşen Uzun Gören, Sedat Karayücel
This study aimed to determine the seasonal vitamin and mineral contents of sea bream (Sparus aurata) cultured in net cages in Central Black Sea region. The average seasonal A, D3 , and E vitamins values in fish meat were between 0.27 ± 0.02-0.60 ± 0.00, 0.98 ± 0.01-1.70 ± 0.00, and 3.10 ± 0.14-6.00 ± 0.21 mg/kg, respectively (p < 0.05). The average seasonal Ca, Fe, K, Mg, Na, P, Zn, and Se values in fish meat were between 276.90 ± 0.99-1788.50 ± 51.27 (p < 0...
May 12, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29754283/association-between-selenium-and-malondialdehyde-as-an-efficient-biomarker-of-oxidative-stress-in-infantile-cardiac-surgery
#12
Marlice Oliveira de Oliveira Ulbrecht, Daniel Araujo Gonçalves, Lourdes Zélia Garcia Zanoni, Valter Aragão do Nascimento
The present work describes a method to quantify the level of oxidative stress in infantile cardiac surgery. Fifteen patients, 6 girls and 9 boys, aged between 3 months and 16 years were divided into three groups. The first group sought to quantify the oxidative stress from differing concentrations of selenium. The second group used malondialdehyde as an indicator of oxidative stress. Finally, the third group quantified oxidative stress by normalizing the selenium concentration via malondialdehyde. Blood aliquots of 1...
May 12, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29748931/selenium-nanoparticles-induce-the-chemo-sensitivity-of-fluorouracil-nanoparticles-in-breast-and-colon-cancer-cells
#13
Ahmed A Abd-Rabou, Aziza B Shalby, Hanaa H Ahmed
Drug resistance is a major challenge of breast and colon cancer therapies leading to treatment failure. The main objective of the current study is to investigate whether selenium nanoparticles (nano-Se) can induce the chemo-sensitivity of 5-fluorouracil (FU)-encapsulated poly (D, L-lactide-co-glycolide) nanoparticles (nano-FU) in breast and colon cancer cell lines. Nano-Se and nano-FU were synthesized and characterized, then applied individually or in combination upon MCF7, MDA-MB-231, HCT 116, and Caco-2 cancerous cell lines...
May 11, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29748930/positive-pcna-and-ki-67-expression-in-the-testis-correlates-with-spermatogenesis-dysfunction-in-fluoride-treated-rats
#14
Wen-Peng Zhao, Hong-Wei Wang, Jing Liu, Pan-Pan Tan, Xiang-Long Luo, Shi-Quan Zhu, Xue-Li Chen, Bian-Hua Zhou
The present study aimed to evaluate the effect of fluoride (F) on spermatogenesis in male rats. F- at 50 and 100 mg/L was administered for 70 days, after which the testicular and epididymis tissues were collected to observe the histopathological structure under a light microscope. The ultrastructure of the testis and sperm was also examined via transmission electron microscopy. The apoptosis of spermatogenic cells was measured through terminal deoxynucleotidyl transferase dUTP nick end labeling staining. The expression of proliferation factors, namely, proliferating cell nuclear antigen (PCNA) and Ki-67, in the testicular and epididymis tissues, were assayed through immunohistochemistry...
May 10, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29748929/toxicological-aspect-of-some-selected-medicinal-plant-samples-collected-from-djelfa-algeria-region
#15
Samir Begaa, Mohammed Messaoudi
Instrumental neutron activation analysis (INAA) has been used to determine the concentration of some toxic chemical elements in a variety of aromatic plants samples collected from Djelfa region. In the present work, eight medicinal plants were examined, such as Artemisia herba-alba Asso., Artemisia compestris L., Laurus nobilis L., Origanum vulgare L., Mentha spicata L., Rosmarinus officinalis L., Mentha pulegium L., and Pistacia lentiscus L. The levels of toxic elements were compared to their daily total intake; Arsenic was present in all plant species examined, with a concentration ranging from 0...
May 10, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29748928/effects-of-humic-acids-in-chronic-lead-poisoning
#16
Janka Vašková, Klára Krempaská, Daniel Žatko, Pavol Mudroň, Gabriela Glinská, Ladislav Vaško
Chronic exposure to lead causes disruption to energy production mechanisms and tissue damage, in particular through its binding to thiol groups and competition for zinc binding sites. We investigated the possibility of preventing the consequences of chronic lead poisoning by administration of three different doses of humic acids (HAs) into feed with the aim of establishing an effective HA dose. During the 10-week experiment, a sub-lethal dose of lead acetate was given to rats during the first 5 weeks, with continuous administration of HA over 10 weeks...
May 10, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29748927/perinatal-exposure-to-arsenic-in-drinking-water-alters-glutamatergic-neurotransmission-in-the-striatum-of-c57bl-6-mice
#17
Kyunghwa Sung, Minjeong Kim, Haesoo Kim, Gi-Wook Hwang, Kisok Kim
Although exposure to arsenic (As) induces developmental neurotoxicity, there is a lack of data regarding its specific effects on glutamatergic neurotransmission in offspring from dams exposed to As during gestation and lactation. In this study, the body weight, glutamate content, and expression of vesicular glutamate transporter 2 (VGLUT2) and metabotropic glutamate receptors mGluR2 and mGluR3 was examined in the striatum of offspring following treatment of the dams with As (10 or 100 mg/L NaAsO2 in drinking water)...
May 10, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29744817/zinc-and-metallothionein-in-the-development-and-progression-of-dental-caries
#18
REVIEW
Mohammad Tariqur Rahman, Ashfaque Hossain, Chew Hooi Pin, Noor Azlin Yahya
Chronic oxidative stress and reactive oxygen species (ROS) in oral cavity as well as acidic pH on dental enamel surface due to the metabolic activities of bacterial plaque are the major contributors in the development and progression of dental caries. Along with other factors, deposition or dissolution Ca and Mg mostly determines the re- or demineralization of dental enamel. Zn plays an important role for both Ca and Mg bioavailability in oral cavity. Metallothionein (MT), a group of small molecular weight, cysteine-rich proteins (~ 7 kDa), is commonly induced by ROS, bacterial infection, and Zn...
May 9, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29740803/du-zhong-eucommia-ulmoides-oliv-cortex-extract-alleviates-lead-acetate-induced-bone-loss-in-rats
#19
Shanshan Qi, Hongxing Zheng, Chen Chen, Hai Jiang
The purpose of this study was to evaluate the protective effect of Du-Zhong cortex extract (DZCE) on lead acetate-induced bone loss in rats. Forty female Sprague-Dawley rats were randomly divided into four groups: group I (control) was provided with distilled water. Group II (PbAc) received 500 ppm lead acetate in drinking water for 60 days. Group III (PbAc+DZCE) received 500 ppm lead acetate in drinking water, and given intragastric DZCE (100 mg/kg body weight) for 60 days. Group IV (DZCE) was given intragastric DZCE (100 mg/kg body weight) for 60 days...
May 9, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29740802/identification-of-biomarkers-of-mercury-contamination-in-brachyplatystoma-filamentosum-of-the-madeira-river-brazil-using-metalloproteomic-strategies
#20
João Vitor de Queiroz, José Cavalcante Souza Vieira, Grasieli de Oliveira, Camila Pereira Braga, Izabela da Cunha Bataglioli, Janaína Macedo da Silva, Wellington Luiz de Paula Araújo, Pedro de Magalhães Padilha
Predator fish can accumulate high levels of mercury, which qualifies them as potential indicators of this toxic metal. The predatory species Brachyplatystoma filamentosum, popularly known as filhote, is among the most consumed species in the Brazilian Amazon. Continuing the metalloproteomic studies of mercury in Amazonian fishes that have been developed in the last 5 years, the present paper provides the data of protein characterization associated with mercury in muscle and liver samples of filhote (Brachyplatystoma filamentosum) collected in the Madeira River, Brazilian Amazon...
May 8, 2018: Biological Trace Element Research
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