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Biological Trace Element Research

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https://www.readbyqxmd.com/read/28921450/nutrients-other-than-selenium-are-important-for-promoting-children-s-health-in-kashin-beck-disease-areas
#1
Yujie Ning, Xi Wang, Xiong Guo, Pan Zhang, Pengfei Qu, Feng Zhang, Sen Wang, Yanxia Lei, Mikko Lammi
Overall nutritional status has been proved associated with people's health. The overall nutritional status of children in Kashin-Beck disease (KBD) areas has been overlooked for decades. Therefore, it is worth investigating in the current generation to gather evidence and make suggestions for improvement. A cross-sectional study with three 24-h dietary recalls was conducted to collect raw data on the daily food intake of children. Recorded food was converted into daily nutrient intakes using CDGSS 3.0 software...
September 18, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28914406/manganese-induced-neurotoxicity-and-alterations-in-gene-expression-in-human-neuroblastoma-sh-sy5y-cells
#2
Deepa Gandhi, Saravanadevi Sivanesan, Krishnamurthi Kannan
Manganese (Mn) is an essential trace element required for many physiological functions including proper biochemical and cellular functioning of the central nervous system (CNS). However, exposure to excess level of Mn through occupational settings or from environmental sources has been associated with neurotoxicity. The cellular and molecular mechanism of Mn-induced neurotoxicity remains unclear. In the current study, we investigated the effects of 30-day exposure to a sub-lethal concentration of Mn (100 μM) in human neuroblastoma cells (SH-SY5Y) using transcriptomic approach...
September 15, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28913818/a-spectroscopic-study-of-interaction-of-auricyanide-with-n-acetylcysteine
#3
Syed G T Kazimi, Mohammad S Iqbal, C Frank Shaw
Interaction of auricyanide, an important metabolite of anti-arthritic gold-based drug auranofin, was studied in vitro with a pharmacologically active ligand n-acetylcysteine with a view to understand reactivity of gold in vivo. Formation of reduction product aurocyanide occurred through mono- and di-n-acetylcysteine-substituted intermediates. The product and intermediates were identified and monitored spectrophotometrically and by electrospray ionization mass spectrometry. This study suggests successive substitution with n-acetylcysteine through trans effect...
September 14, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28913781/effects-of-fluoride-and-or-sulfur-dioxide-on-morphology-and-dna-integrity-in-rats-hepatic-tissue
#4
Chen Liang, Yan Gao, Yangfei Zhao, Ram Kumar Manthari, Junjie Ma, Ruiyan Niu, Jinming Wang, Jianhai Zhang, Jundong Wang
This study was aimed to evaluate the toxic effects of fluoride (F) and/or sulfur dioxide (SO2) on morphology and DNA integrity in liver of male rats. For this, 96 Wistar rats (12-week-old) were randomly divided into four groups after 1-week adaptive breeding: the control group, treated with deionized water; the NaF group, administered high F (100 mg NaF/L in the drinking water); the SO2 group, with sulfur dioxide in ambient air (15 ppm SO2, 4 h/day); and NaF + SO2 group, treated with high F and sulfur dioxide together for 8 consecutive weeks...
September 14, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28905315/preliminary-studies-of-acute-cadmium-administration-effects-on-the-calcium-activated-potassium-skca-and-bkca-channels-and-na-k-atpase-activity-in-isolated-aortic-rings-of-rats
#5
Dalton V Vassallo, Camila C P Almenara, Gilson Brás Broseghini-Filho, Ariane Calazans Teixeira, David Chaves F da Silva, Jhuli K Angeli, Alessandra S Padilha
Cadmium is an environmental pollutant closely linked with cardiovascular diseases that seems to involve endothelium dysfunction and reduced nitric oxide (NO) bioavailability. Knowing that NO causes dilatation through the activation of potassium channels and Na(+)/K(+)-ATPase, we aimed to determine whether acute cadmium administration (10 μM) alters the participation of K(+) channels, voltage-activated calcium channel, and Na(+)/K(+)-ATPase activity in vascular function of isolated aortic rings of rats. Cadmium did not modify the acetylcholine-induced relaxation...
September 13, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28895044/effect-of-zinc-supplementation-on-growth-performance-intestinal-development-and-intestinal-barrier-related-gene-expression-in-pekin-ducks
#6
Min Wen, Hua Zhao, Guangmang Liu, Xiaoling Chen, Bing Wu, Gang Tian, Jingyi Cai, Gang Jia
The current study was conducted to investigate the effect of zinc supplementation on the growth performance, intestinal morphology, and the transcription of the barrier function related genes in Pekin ducks. Seven-hundred and sixty-eight 1-day-old Pekin ducks were randomly assigned into six dietary treatments. Each treatment had eight replicates with 16 ducks per replicates. The ducks were fed either a corn-soybean meal basal diet or basal diets supplemented with 15, 30, 60, 120, and 240 mg zinc/kg from zinc sulfate...
September 11, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28887675/how-bad-is-aluminum-exposure-to-reproductive-parameters-in-rats
#7
Viviane G S Mouro, Tatiana P Menezes, Graziela D A Lima, Rafael R Domingues, Ana Cláudia F Souza, Juraci A Oliveira, Sérgio L P Matta, Mariana Machado-Neves
Aluminum (Al) is the most widely distributed metal in the environment and is extensively used in human daily life without any known biological function. It is known that exposure to high concentrations of Al impacts negatively on serum testosterone levels, testicular histomorphometry, and sperm parameters; however, no information is available about the effects of low exposure levels on reproduction. International organizations have established the Al concentration tolerated in drinking water as 3.35 × 10(-4) mg/kg...
September 8, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28884459/the-study-on-the-correlation-between-six-kinds-of-mineral-elements-and-diabetes
#8
Zhuo Li, Changcong Wang, Lu Li, Mengyun Shao, Linbo Wang, Xin Lv, Chunshi Gao, Huikun Niu, Bo Li
The study aimed to explore the relationship of six kinds of mineral elements and diabetes among adults in northeast China. A cross-sectional survey was conducted in Jilin Province, northeast China. A total of 366 males and 204 females aged 18 ~ 77 years from Jingyu town, Dongliao town, and Changling town were included using a multistage stratified random cluster sampling design. Data was obtained from face to face interview, physical examination, and laboratory measurement. We defined the normal people (3...
September 7, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28879636/-cr3o-o2cch2ch3-6-h2o-3-no3%C3%A2-h2o-cr3-toxicity-potential-in-bacterial-and-mammalian-cells
#9
Lu Jiang, John B Vincent, Melissa M Bailey
Chromium(III) has generally been considered to be essential for proper carbohydrate and lipid metabolism, and, despite recent evidence to the contrary, chromium(III)-containing compounds remain one of the most popular commercial dietary supplements. Cr3, or [Cr3O(O2CCH2CH3)6(H2O)3]NO3·H2O, is a trivalent chromium compound that is a promising chromium nutritional supplement. Studies with Cr3 have indicated that it is non-toxic in developmental and short- and long-term exposure studies in rodents, but the safety of this compound to chromosomes and cells has not been explored...
September 7, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28879625/effects-of-arsenic-compounds-on-microminerals-content-and-antioxidant-enzyme-activities-in-rat-liver
#10
Ana Cláudia Ferreira Souza, Sarah Cozzer Marchesi, Graziela Domingues de Almeida Lima, Mariana Machado-Neves
Interactions of arsenic with essential trace elements may result in disturbances on body homeostasis. In the present study, we aimed to investigate the effects of different arsenic compounds on micromineral content and antioxidant enzyme activities in rat liver. Male Wistar rats were randomly divided into five groups and exposed to sodium arsenite and sodium arsenate at 0.01 and 10 mg/L for 8 weeks in drinking water. The concentration of arsenic increased in the liver of all arsenic-exposed animals. The proportion of zinc and copper increased in animals exposed to 0...
September 6, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28875327/the-effects-of-selenium-supplementation-on-gene-expression-related-to-insulin-and-lipid-in-infertile-polycystic-ovary-syndrome-women-candidate-for-in-vitro-fertilization-a-randomized-double-blind-placebo-controlled-trial
#11
Shahrzad Zadeh Modarres, Zahra Heidar, Fatemeh Foroozanfard, Zahra Rahmati, Esmat Aghadavod, Zatollah Asemi
This study was conducted to evaluate the effects of selenium supplementation on gene expression related to insulin and lipid in infertile women with polycystic ovary syndrome (PCOS) candidate for in vitro fertilization (IVF). This randomized double-blind, placebo-controlled trial was conducted among 40 infertile women with PCOS candidate for IVF. Subjects were randomly allocated into two groups to intake either 200-μg selenium (n = 20) or placebo (n = 20) per day for 8 weeks. Gene expression levels related to insulin and lipid were quantified in lymphocytes of women with PCOS candidate for IVF with RT-PCR method...
September 5, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28871485/inflammatory-response-occurs-in-veins-of-broiler-chickens-treated-with-a-selenium-deficiency-diet
#12
Changyu Cao, Ruifeng Fan, Menghao Chen, Xiaojing Li, Mengyuan Xing, Fating Zhu, Hua Xue, Kai Wang, Shiwen Xu
Selenium (Se) has been indicated to prevent chronic diseases including cancer, cardiovascular disease, and type 2 diabetes. However, a few studies have indicated that Se deficiency can induce vascular diseases. Thus, in the present study, we investigated the effect of Se deficiency on vascular pathology. A total of 60 male broiler chickens were randomly divided into 2 groups (n = 30). The control group (C group) was fed a basic diet, and the Se-deficient group (L group) was fed a Se-deficient, corn-soy-based diet...
September 4, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28866860/protective-effects-of-dietary-garlic-powder-against-cadmium-induced-toxicity-in-sea-bass-liver-a-chemical-biochemical-and-transcriptomic-approach
#13
Amin Mosbah, Hamadi Guerbej, Hamadi Boussetta, Zied Bouraoui, Mohamed Banni
To investigate the protective effect of garlic powder on cadmium-induced toxicity sea bass liver, juvenile fishes where maintained under three food diets (diet 1: normal without garlic supply, diet 2: 2% garlic powder; diet 3: 6% garlic powder). After 30 days of specific diets, each group was injected with 500 μg kg(-1)of Cd. The control group was the one fed with normal diet and not injected with Cd. Liver Cd, Zn, and Se loads was assessed after 1 and 3 days of Cd injections. Moreover, antioxidant enzymes activities termed as catalase, superoxide dismutase, and glutathione peroxydase as well as their gene expression levels were monitored...
September 2, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28866820/copper-manganese-zinc-and-cadmium-in-tea-leaves-of-different-types-and-origin
#14
W Podwika, K Kleszcz, M Krośniak, P Zagrodzki
Concentrations of selected metals (Cu, Mn, Zn, Cd) in tea leaves were investigated. Samples included black, green, and other (red, white, yellow, and oolong) teas. They were purchased on a local market but they covered different countries of origin. Beverages like yerba mate, rooibos, and fruit teas were also included in the discussion. Metal determinations were performed using atomic absorption spectrometry. In black teas, Mn/Cd ratio was found to be significantly higher (48,091 ± 35,436) vs. green (21,319 ± 16,396) or other teas (15,692 ± 8393), while Cd concentration was lower (31...
September 2, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28864954/comparison-of-the-trace-elements-and-active-components-of-lonicera-japonica-flos-and-lonicera-flos-using-icp-ms-and-hplc-pda
#15
Yueran Zhao, Deqiang Dou, Yueqiu Guo, Yue Qi, Jun Li, Dong Jia
Thirteen trace elements and active constituents of 40 batches of Lonicera japonica flos and Lonicera flos were comparatively studied using inductively coupled plasma mass-spectrometry (ICP-MS) and high-performance liquid chromatography-photodiode array (HPLC-PDA). The trace elements were (24)Mg, (52)Cr, (55)Mn, (57)Fe, (60)Ni, (63)Cu, (66)Zn, (75)As, (82)Se, (98)Mo, (114)Cd, (202)Hg, and (208)Pb, and the active compounds were chlorogenic acid, 3,5-O-dicaffeoylquinc acid, 4,5-O-dicaffeoylquinc acid, luteolin-7-O-glucoside, and 4-O-caffeoylquinic acid...
September 1, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28861860/interaction-of-lead-with-calcium-iron-and-zinc-in-the-biological-samples-of-malnourished-children
#16
Sehrish Talpur, Hassan I Afridi, Tasneem G Kazi, Farah Naz Talpur
Interaction between toxic and essential elements is of particular interest, because the deficiency of essential element can dramatically increase the absorption rate of toxic metals inside the body. This study was conducted to evaluate the possible correlation of lead (Pb) with calcium (Ca), iron (Fe), and zinc (Zn) in biological samples (whole blood and scalp hair) of malnourished children (MNC). For comparative purposes, age-matched, well-nourished children (WNC) were selected. The concentrations of understudy elements were analyzed by atomic absorption spectrophotometry after microwave acid digestion...
August 31, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28856635/umbilical-serum-copper-status-and-neonatal-birth-outcomes-a-prospective-cohort-study
#17
Zhijuan Li, Chunmei Liang, Kun Huang, Shuangqin Yan, Ruiwen Tao, Jie Sheng, Weijun Pan, Xun Xia, Yiran Tao, Haiyun Xiang, Jiahu Hao, Beibei Zhu, Qunan Wang, Peng Zhu, Shilu Tong, Fangbiao Tao
Our study aimed to assess the distribution of copper (Cu) in umbilical cord serum and estimated the association between umbilical serum Cu status and neonatal birth outcomes in a Chinese population. Through the Ma'anShan Birth Cohort Study, 2689 maternal-singleton pairs with detailed birth records and available serum samples were identified. The tertile levels of ln-transformed Cu were used to define low, medium, and high levels for serum Cu. The median for umbilical cord serum Cu was 298.2 μg/L with a range of 123...
August 31, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28856601/chromium-supplementation-reduces-resting-heart-rate-in-patients-with-metabolic-syndrome-and-impaired-glucose-tolerance
#18
Barbora Nussbaumerova, Hana Rosolova, Miroslav Krizek, Frantisek Sefrna, Jaroslav Racek, Ludek Müller, Christian Sindberg
Chromium (Cr) is considered as an important mineral, involved in biochemical reactions in human metabolic pathways. Organically bound Cr supplementation has been suggested to improve glycemia especially in patients with type 2 diabetes mellitus, but there are conflicting reports on efficacy. Effect of Cr is not clear in prediabetes status. Seventy patients with metabolic syndrome and impaired glucose tolerance (IGT), who are observed and treated in the Center of Preventive Cardiology of the University Hospital in Pilsen, were included in the prospective, randomized, double-blind, and placebo-controlled clinical study...
August 30, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28856594/size-dependent-neurotoxicity-of-aluminum-oxide-particles-a-comparison-between-nano-and-micrometer-size-on-the-basis-of-mitochondrial-oxidative-damage
#19
Atefeh Mirshafa, Mehdi Nazari, Daniel Jahani, Fatemeh Shaki
Aluminum nanoparticles (AlNPs) are among the most abundantly produced nanosized particles in the market. There is limited information about the potential harmful effects of aluminum oxide due to its particle size on human health. Considering the toxic effects of Al on brain as its target tissue, in this study, the toxicity of nanoparticles, microparticles, and ionic forms of Al on rat brain and isolated mitochondria was evaluated. Sixty male Wistar rats were divided into ten groups (six rats each), in which group I was the control, and the other groups were administered different doses of Al nanoparticles, Al microparticles (AlMP), and Al ionic forms (2, 4, and 8 mg/kg, i...
August 30, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28856574/aluminum-chloride-causes-the-dysfunction-of-testes-through-inhibiting-the-atpase-enzyme-activities-and-gonadotropin-receptor-expression-in-rats
#20
Xudong Sun, Hao Sun, Kaiyuan Yu, Zhongying Wang, Yanfen Liu, Kexiang Liu, Yanzhu Zhu, Yanfei Li
The aim of this experiment is to explore the effects of aluminum chloride (AlCl3) on the ATPase enzymes and gonadotropin receptors in the testes. Eighty male Wistar rats were orally exposed to 0 mg/kg body weight (BW) (control group, CG), 64 mg/kg BW (low-dose group, LG), 128 mg/kg BW (mid-dose group, MG), or 256 mg/kg BW (high-dose group, HG) for 120 days. The microstructure and ultrastructure of testes; the activities of Na(+)-K(+)-ATPase, Mg(2+)-ATPase, and Ca(2+)-ATPase; and the mRNA and protein expressions of follicle-stimulating hormone receptor (FSHR) and luteinizing hormone receptors (LHR) in the testes were examined...
August 30, 2017: Biological Trace Element Research
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