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Psychiatry Research

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https://www.readbyqxmd.com/read/29334658/contextual-determinants-of-psychopathology-the-singularity-of-attachment-as-a-predictor-of-mental-dysfunction
#1
Yolanda Alonso, Javier Fernández, Yolanda Fontanil, Esteban Ezama, Alberto Gimeno
The general aim of this research is to evaluate the singular weight of attachment relationships in psychopathology, to determine the point to which these relationships cannot be subsumed by other variables that are famously related to attachment, such as experience of stressful life events, social support, and coping styles. 172 people treated in mental health centers provided data related to these four aspects and about manifestations of psychopathology. Multiple linear regression analyses determined that 51% of the variance in the level of symptomatology is explained with six variables: two related to adult attachment (fear of rejection and abandonment in romantic relationships, and the degree of similarity to the fearful prototype), one related to social support (family appreciation), one to life events (overall perceived stress), and two to coping style (cognitive restructuring and social withdrawal)...
January 9, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29334659/serum-zinc-levels-in-acute-psychiatric-patients-a-case-series
#2
Peter Joe, Mara Getz, Samantha Redman, Matthew Petrilli, Thorsten Manfred Kranz, Samoon Ahmad, Dolores Malaspina
Zinc dysregulation is linked to neuropsychiatric disorders and a beneficial response to zinc supplementation has been demonstrated for depression. In this case series, we examined serum zinc levels with respect to clinical factors among 20 acutely ill psychiatric cases admitted to a large urban public hospital. The results showed frank clinical zinc insufficiency in a quarter of the subjects. Group-wise analyses showed a significant association between reduced serum zinc and diagnosis of depression, and reduced serum zinc in those with aggressive, assaultive, or violent behaviors...
January 6, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29334657/relationship-of-obsessive-compulsive-symptoms-to-clinical-variables-and-cognitive-functions-in-individuals-at-ultra-high-risk-for-psychosis
#3
Ahmet Zihni Soyata, Selin Akışık, Damla İnhanlı, Handan Noyan, Alp Üçok
Few studies have investigated the relationship between obsessive-compulsive symptoms (OCS) and clinical variables, and cognition in individuals at ultra high-risk (UHR) for psychosis. The aim of this study was to evaluate the frequency of OCS and their relationship with clinical variables and cognitive functions in individuals at UHR. Eighty-four individuals at UHR for psychosis were administered the Brief Psychiatric Rating Scale, the Yale-Brown Obsession Compulsion Symptom Check List and, the Calgary Depression Scale for Schizophrenia...
January 6, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329039/an-investigation-into-the-drivers-of-avolition-in-schizophrenia
#4
Gaurav Suri, Lindsey M Lavaysse, Gerald Young, Craig Moodie, Alen Tersakyan, James J Gross, David E Gard
Over a century of research has documented that avolition is a core symptom in schizophrenia. However, the drivers of avolition remain unclear. Conceptually, there are at least two potential mutually compatible drivers that could cause avolition in schizophrenia. First, people with schizophrenia might have differences in preferences that result in less goal-directed behavior than non-clinical populations (preference-differences). Second, people with schizophrenia might have difficulty translating their preferences into manifest behavior at rates similar to non-clinical populations (psychological-inertia)...
January 6, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29331849/sociodemographic-lifestyle-and-health-determinants-of-suicidal-behaviour-in-malaysia
#5
Yong Kang Cheah, Mohd Azahadi, Siew Nooi Phang, Noor Hazilah Abd Manaf
Suicide has become a serious matter in both developed and developing countries. The objective of the present study is to examine the factors affecting suicidal behaviour among adults in Malaysia. A nationally representative data which consists of 10,141 respondents is used for analysis. A trivariate probit model is utilised to identify the probability of having suicide ideation, suicide plan and suicide attempt. Results of the regression analysis show that to ensure unbiased estimates, a trivariate probit model should be used instead of three separate probit models...
January 5, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29331848/repetitive-transcranial-magnetic-stimulation-for-apathy-in-mild-cognitive-impairment-a-double-blind-randomized-sham-controlled-cross-over-pilot-study
#6
Prasad R Padala, Kalpana P Padala, Shelly Y Lensing, Andrea N Jackson, Cassandra R Hunter, Christopher M Parkes, Richard A Dennis, Melinda M Bopp, Ricardo Caceda, Mark S Mennemeier, Paula K Roberson, Dennis H Sullivan
Apathy is a common and disabling behavioral concomitant of many neurodegenerative conditions. The presence of apathy with Mild Cognitive Impairment (MCI) is linked with heightened rates of conversion to Alzheimer's disease. Improving apathy may slow the neurodegenerative process. The objective was to establish the efficacy of repetitive transcranial magnetic stimulation (rTMS) in improving apathy in older adults with MCI. An 8-week, double-blind, randomized, sham-controlled cross-over study was conducted in nine subjects (66 ± 9 years) with apathy and MCI...
January 5, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329050/factors-influencing-the-severity-of-behavioral-phenotype-in-autism-spectrum-disorders-implications-for-research
#7
Mingyang Zou, Caihong Sun, Jia Wang, Jing Kang, Zhanbin Xu, Yongjuan Ma, Lei Chen, Xinxi Zhang, Wei Xia, Lijie Wu
The phenotypic heterogeneity of Autism Spectrum Disorders (ASD) presents particular research challenges in the assessment of symptom severity, while the standardized Autism Diagnostic Observation Schedule (ADOS) scores present a severity metric, namely calibrated severity scores (CSS) that are relatively impervious to individual characteristics. To date, no studies have examined the convergent validity of CSS in Chinese sample populations. The present study investigated the validity of the ADOS-CSS using a sample of 321 children aged 2-18 years with ASD, and developed upon existing literature examining the influence of non-ASD-specific characteristics on other types of measures including Autism Diagnostic Interview-Revised (ADI-R), Social Responsiveness Scale (SRS), and Vineland Adaptive Behavior Scales (VABS)...
January 5, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329049/the-traumatized-body-long-term-ptsd-and-its-implications-for-the-orientation-towards-bodily-signals
#8
Noga Tsur, Ruth Defrin, Yael Lahav, Zahava Solomon
Orientation to bodily signals is defined as the way somatic sensations are attended, perceived and interpreted. Research suggests that trauma exposure, particularly the pathological reaction to trauma (i.e., PTSD), is associated with catastrophic and frightful orientation to bodily signals. However, little is known regarding the long-term ramifications of trauma exposure and PTSD for orientation to bodily signals. Less is known regarding which PTSD symptom cluster manifests in the 'somatic route' through which orientation to bodily signals is altered...
January 5, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29331850/attentional-biases-in-patients-suffering-from-unipolar-depression-results-of-a-dot-probe-task-investigation
#9
Wolfgang Trapp, Christoph Kalzendorf, Corinna Baum, Göran Hajak, Stefan Lautenbacher
Cognitive models of depression emphasize the relevance of cognitive biases for development, onset and maintenance of major depressive disorder (MDD). Attentional biases consisting of increased attention to negative, mood congruent stimuli and reduced attention to positive, mood-incongruent stimuli are postulated but have rarely been tested for early attentional processing. Furthermore, the role of concurrent depressive mood as a moderating factor has not been studied to date. Participants comprised 30 patients suffering from MDD and 30 healthy control subjects...
January 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329044/neurological-soft-signs-in-bipolar-and-unipolar-disorder-a-case-control-study
#10
Tareq Al Sagheer, Shafika Assaad, Georges Haddad, Dory Hachem, Chadia Haddad, Souheil Hallit
Neuropsychiatric disorders are associated with neurological soft signs (NSS), including motor, sensory, and inhibitory dysfunction. The present study aims at determining the prevalence of NSS and explore the association of sociodemographic characteristics with the occurrence of NSS in patients with bipolar disorder and unipolar depression compared to healthy controls. A case-control study included a sample of 50 bipolar and unipolar patients and 50 healthy controls. NSS subscales of the Neurological Evaluation Scale (NES) were administered to each participant...
January 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29316458/self-reported-violent-ideation-and-its-link-to-interpersonal-violence-among-offenders-with-mental-disorders-and-general-psychiatric-patients
#11
Mats Persson, Joakim Sturup, Henrik Belfrage, Marianne Kristiansson
This study aims at comparing mentally disordered offenders and general psychiatric patients regarding violent ideation and at exploring its association with interpersonal violence. We recruited 200 detainees undergoing forensic psychiatric evaluation and 390 general psychiatric patients at discharge. At baseline, they were asked about violent ideation; at the 20-week follow-up, information about violent acts was gathered from crime conviction registry, interviews, and records. The lifetime prevalence of violent ideation was 32...
January 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29331710/maternal-depression-and-suicide-at-immediate-prenatal-and-early-postpartum-periods-and-psychosocial-risk-factors
#12
Peixia Shi, Hui Ren, Hong Li, Qin Dai
Maternal depression has been intensively explored; however, less attention has been paid to maternal suicide. No studies to date have observed maternal depression and suicide at immediate prenatal and early postpartum stages. In total, 213 Chinese women were recruited in hospitals after they were admitted for childbirth. All completed a short-term longitudinal survey at perinatal stages. Women reported lower depression scores (6.65) and higher suicidal ideation incidence (11.74%) after childbirth. Prenatal depression raised the possibility of prenatal suicidal ideation, while prenatal depression and suicidal ideation increased postpartum depression and suicidal ideation...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329743/gaba-and-glutamate-in-children-with-tourette-syndrome-a-1h-mr-spectroscopy-study-at-7t
#13
E Mark Mahone, Nicolaas A Puts, Richard A E Edden, Matthew Ryan, Harvey S Singer
Tourette syndrome (TS) is characterized by presence of chronic, fluctuating motor and phonic tics. The underlying neurobiological basis for these movements is hypothesized to involve cortical-striatal-thalamo-cortical (CSTC) pathways. Two major neurotransmitters within these circuits are γ-aminobutyric acid (GABA) and glutamate. Seventy-five participants (32 with TS, 43 controls) ages 5-12 years completed 1H MRS at 7T. GABA and glutamate were measured in dorsolateral prefrontal cortex (DLPFC), ventromedial prefrontal cortex (VMPFC), premotor cortex (PMC), and striatum, and metabolites quantified using LCModel...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329048/characterizing-anger-related-affect-in-individuals-with-posttraumatic-stress-disorder-using-ecological-momentary-assessment
#14
Elizabeth E Van Voorhees, Paul A Dennis, Eric B Elbogen, Bernard Fuemmeler, Lydia C Neal, Patrick S Calhoun, Jean C Beckham
This study employed secondary analyses of existing ecological momentary assessment (EMA) data to characterize hostile and irritable affect in the day-to-day experience of 52 smokers with, and 65 smokers without, posttraumatic stress disorder (PTSD). EMA monitoring occurred over a mean of 8.2 days, and participants responded to an average of 2.8 random prompts/day. Analyses included Wilcoxon rank sum tests of group differences, and path analyses of cross-lagged multilevel models. Participants with PTSD endorsed a significantly higher proportion of total EMA entries indicating hostile affect and irritable affect than did individuals without PTSD...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329047/the-connection-between-subjective-nearness-to-death-and-depressive-symptoms-the-mediating-role-of-meaning-in-life
#15
Yoav S Bergman, Ehud Bodner, Ye'ela Haber
Depression is characterized by a wide range of emotional, cognitive, and physical symptoms. Two prominent features of depressive symptoms are a sense that life has no meaning on the one hand, and that life is not worth living on the other hand. In recent years, the subjective perception of how close one feels to his/her death has gained importance as a significant factor associated with various aspects of physical and psychological well-being. Thus, the current study examined the connection between subjective nearness-to-death, meaning in life, and depressive symptoms, and assessed whether meaning in life mediates the connection between subjective nearness-to-death and depressive symptoms...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329045/increased-depression-symptom-score-in-newly-diagnosed-type-2-diabetes-patients
#16
Wolfgang Rathmann, Oliver Kuß, Dörte Anderson, Stefan Busch, Michael Hahn, Johanna Engelhard, Ming Zou, Karel Kostev
The aim was to investigate the association between diabetes duration and depressive symptoms in type 2 diabetes. The DIAREG registry used data of a nationwide general medicine practice database (Disease Analyzer, Germany) augmented by prospective data from patient reported outcomes (PRO) including Center of Epidemiological Studies Depression Scale (CES-D: <16 vs. ≥16) and the SF-36. Multiple logistic regression models were used to investigate the association of diabetes duration with PROs. Overall, 1807 type 2 diabetes patients were registered in 108 practices...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329043/impact-of-synthetic-cannabinoid-use-on-hospital-stay-in-patients-with-bipolar-disorder-versus-schizophrenia-or-other-psychotic-disorders
#17
Huiqiong Deng, Satyajit Mohite, Robert Suchting, David A Nielsen, Olaoluwa O Okusaga
Synthetic cannabinoid products have become popular and have led to an increased number of patients presenting to emergency departments and psychiatric hospitals. The purpose of this study was to evaluate the impact of synthetic cannabinoid use at admission on length of stay and doses of antipsychotics at discharge in individuals with bipolar disorder, schizophrenia and other psychotic disorders. We retrospectively examined medical records of 324 inpatients admitted from January 2014 to July 2015. We found that synthetic cannabinoid use predicted length of stay and antipsychotic dose using structural equation modeling...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29324396/cyberchondria-overlap-with-health-anxiety-and-unique-relations-with-impairment-quality-of-life-and-service-utilization
#18
Brittany M Mathes, Aaron M Norr, Nicholas P Allan, Brian J Albanese, Norman B Schmidt
Cyberchondria refers to a clinical phenomenon in which repeated Internet searches regarding medical information result in excessive concerns about physical health. Cyberchondria is positively associated with symptoms of health anxiety, though it remains unclear as to whether cyberchondria poses a unique public burden. The current study replicated previous findings regarding the relationship between cyberchondria and health anxiety, and extended those findings to examine the extent to which health anxiety and cyberchondria may be differentially associated with public health outcomes, including impairment, quality of life, and service utilization...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29309959/mental-disorders-and-suicide-attempt-in-rural-china
#19
Bao-Peng Liu, Ping Qin, Yang-Yang Liu, Lu Yuan, Ling-Xi Gu, Cun-Xian Jia
The prevalence of various mental disorders and their age and gender specific characteristics among suicide attempters remains unclear in rural China. This study using 1:1 paired case-control design included 409 suicide attempters and 409 paired controls matched on age, gender and place of residence. Mental disorders were assessed using the Structured Clinical Interview for DSM-IV-TR Axis I Disorders. The prevalence of mental disorders was 32.3% for suicide attempters and 4.9% for paired controls. Mental disorder constituted a significant risk factor for suicide attempt with an adjusted odds ratio of 7...
January 3, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29329046/social-distance-toward-people-with-schizophrenia-is-associated-with-favorable-understanding-and-negative-stereotype
#20
Shinsuke Koike, Sosei Yamaguchi, Yasutaka Ojio, Shuntaro Ando
Previous studies have suggested the consequence of mental health-related public stigma: the problem of knowledge may develop into problem of attitude and behaviour. However, this has not been directly explored in a longitudinal study. As the secondary analysis from our previous randomized controlled trial (RCT) for 219 participants who completed the survey at the 12-month follow-up, we aimed to investigate whether the knowledge and attitude components of stigma toward people with schizophrenia affect each other...
January 2, 2018: Psychiatry Research
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