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Psychiatry Research

Paulo Rocha, Humberto Correa
Sleep disturbances are feasibly linked with poorer outcome in BD. This study aims to cross-sectionally investigate clinical factors associated with sleep disruption in euthymic BD patients. We assessed sleep quality in a sample of 209 euthymic BD patients with the Pittsburgh Sleep Quality Index. After multiple logistic regression analysis controlling for several confounding factors, the variables number of clinical diseases and Hamilton global score remained significant and independently associated with poor sleep quality...
July 12, 2018: Psychiatry Research
David Kealy, Simon M Rice, John S Ogrodniczuk, Alicia Spidel
Previous research suggests a link between experiences of childhood maltreatment and adult somatic symptom distress. Contributing mechanisms, however, are not yet well understood. It is possible that shame and guilt may function as mediators in the relationship between childhood trauma and adult somatic distress. The present study was developed to investigate the relationship between childhood maltreatment and adult somatic distress, including the potential mediating role of shame and guilt, among psychiatric outpatients...
July 11, 2018: Psychiatry Research
Noelle B Smith, Lauren M Sippel, Candice Presseau, David Rozek, Natalie Mota, Charles Gordon, Mark Horvath, Ilan Harpaz-Rotem
Given elevated rates of posttraumatic stress disorder (PTSD) among US military veterans, identifying correlates of PTSD and specific PTSD symptom clusters that best represent PTSD in veterans (i.e., the five-factor Dysphoric Arousal model) is critical to prevention and intervention efforts. One potential correlate is locus of control (i.e., the extent to which individuals believe they have control over events in their lives). The aim of this study was to examine the relations between locus of control and five-factor model PTSD symptom clusters (i...
July 11, 2018: Psychiatry Research
Sydney Osland, Paul D Arnold, Tamara Pringsheim
The objective of this study was to provide epidemiological data regarding obsessive compulsive disorder (OCD) in Canada, and examine related conditions, childhood experiences and healthcare utilization. A Statistics Canada population-based health survey was utilized (N = 25,097). The prevalence of diagnosed OCD in Canada was 0.93% (95% CI 0.75-1.11). People with OCD were younger and more likely to have lower incomes. They were more likely to have mood disorders including depression and bipolar disorder (both diagnosed conditions and by screening), and generalized anxiety disorder...
July 11, 2018: Psychiatry Research
Jessica J Zakrzewski, Samir Datta, Carole Scherling, Krystal Nizar, Ofilio Vigil, Howard Rosen, Carol A Mathews
Hoarding disorder (HD) has been hypothesized to arise from deficits in error monitoring and abnormalities in emotional processing, but the relationship between error monitoring and emotional processing has not been examined. We examined measures of self-report, as well as behavioral, physiological, and facial responses to errors during a Stop-Change Task. 25 participants with HD and 32 healthy controls (HC) were recruited. Participants reported on number of errors committed and pre/post emotional response to errors...
July 10, 2018: Psychiatry Research
Mohamad Davood Mohebi, Erfan Ayubi, Ali Azmoodeh, Narjes Sargolzaie
Very little research done on the relationship between identity styles and addiction vulnerability among university students. This study aims to evaluate the extent to which identity styles can influence addiction vulnerability among medical students in Zahedan, Iran. The present cross-sectional study being conducted at Zahedan University of Medical Sciences from 2015 to 2016. The study sample consisted of 205 pre-clinical medical students (60% Female, 40% male) recruited. Berzonsky's Identity Style Questionnaire and Addiction Potential questionnaire, respectively measured "Identity Styles and addiction vulnerability"...
July 9, 2018: Psychiatry Research
Brian I O'Toole, Mark Dadds, Melanie J Burton, Alice Rothwell, Stanley V Catts
A non-clinical sample of male Australian Vietnam veterans, their wives, and adult offspring were interviewed in-person in a national epidemiological study to assess the relationship between the mental ill-health of veterans and the emotional climate of the family while the children were growing up. Veterans were assessed 17 years before their children using standardised psychiatric diagnostic interviews. Family emotional climate was assessed using offspring ratings of parental attachment, and codings of positive and negative family relationship styles based on five minute speech samples provided by the offspring...
July 9, 2018: Psychiatry Research
Xia Zhao, Dan Zhang, Menglian Wu, Yang Yang, Hui Xie, Yuqin Li, Jihui Jia, Yonggang Su
Loneliness has been identified as a risk factor for depressive symptoms. Resilience and social support have been regarded as underlying protective factors. Little is known about the complex relations among these factors in the nursing home elderly. This study aimed to assess the prevalence of depressive symptoms, explore whether resilience mediated the association between loneliness and depressive symptoms, and investigate whether social support moderated the indirect or direct effect of mediation model. A total of 323 nursing home elderly were recruited in Jinan City, China...
July 9, 2018: Psychiatry Research
Parita Shah, Yusuke Iwata, Eric Plitman, Eric E Brown, Fernando Caravaggio, Julia Kim, Shinichiro Nakajima, Margaret Hahn, Gary Remington, Philip Gerretsen, Ariel Graff-Guerrero
Approximately one-third of patients with schizophrenia have treatment-resistant schizophrenia (TR-SCZ), which is a condition characterized by suboptimal response to antipsychotics other than clozapine. Importantly, treatment with clozapine-the only antipsychotic with an indication for TR-SCZ-is often delayed, which could contribute to negative outcomes. Given that the specific impact of delay in clozapine initiation is not well understood, we aimed to conduct a systematic search of the Ovid Medline® database to identify English language publications exploring the impact of delay in clozapine initiation on treatment outcomes in patients with TR-SCZ...
July 9, 2018: Psychiatry Research
Li Lu, Dan-Dan Xu, Huan-Zhong Liu, Ling Zhang, Chee H Ng, Gabor S Ungvari, Feng-Rong An, Yu-Tao Xiang
Internet addiction (IA) is common amongst young people, but no data on IA are available in Tibetan middle school students in China. This study compared the prevalence of IA between Tibetan and Han Chinese middle school students, and examined its association with quality of life. The study was conducted in two middle schools in the Tibetan area of Qinghai province and two Han Chinese middle schools in Anhui province, China. Internet addiction, depressive symptoms and quality of life were measured using standardized instruments...
July 7, 2018: Psychiatry Research
Cyrielle Derguy, Solenne Roux, Marine Portex, Katia M'bailara
The aim of this study was to assess the respective weight of individual and environmental factors on quality of life (Qol) of parents of children with autism spectrum disorders (ASD). Few studies have investigated both individual and environmental predictors of Qol but to our knowledge, none of them has considered the child's and parents' characteristics, family context and services available in the same design. Participants were 115 parents (73 mothers and 42 fathers) of children with ASD aged from 3 to 10 years...
July 7, 2018: Psychiatry Research
João Viseu, Rita Leal, Saul Neves de Jesus, Patrícia Pinto, Pedro Pechorro, Esther Greenglass
The economic crisis had a detrimental impact on the economies of several European countries, namely in Portugal. The literature emphasizes that periods of economic turmoil potentiate the appearance of mental health issues, such as stress, anxiety, and depression, and decrease populations' well-being. The present study, conducted in Portugal, was performed with a sample of 729 individuals, 33.9% males and 66.1% females, with an average age of 36.99 years old. Its' aim was to assess the relationship between economic stress factors (economic hardship, financial threat, and financial well-being) and stress, anxiety, and depression, as well as to test the moderating effect of social support on this relationship...
July 7, 2018: Psychiatry Research
Charles Jardin, Daniel J Paulus, Lorra Garey, Brooke Kauffman, Jafar Bakhshaie, Kara Manning, Nubia A Mayorga, Michael J Zvolensky
The present study examined the factor structure, invariance properties, reliability, and validity of the Anxiety Sensitivity Index-3 (ASI-3, Taylor et al., 2007). Participants were recruited from a large, ethnically diverse southwestern university (n = 3651; 77.8% female; Mage  = 22.06 years; 28% non-Hispanic White). Findings supported a bifactor structure for the ASI-3, which demonstrated measurement invariance across sex, race/ethnicity, age, and sexual minority status. Furthermore, the ASI-3 demonstrated strong reliability and validity, with the anxiety sensitivity general and specific factors (physical, cognitive, and social concerns) evidencing unique patterns of relations with symptoms of depression, suicidality, anxious arousal, and social anxiety...
July 7, 2018: Psychiatry Research
Chao Zhou, Jiu Chen, Xiaowei Tang, Xiaotang Feng, Miao Yu, Weiwei Sha, Xiang Wang, Xiaobin Zhang, Hongwei Yi, Xiangrong Zhang
This study detected the differences in gene expression and DNA methylation of CpG sites in CXCL1 gene and further investigated their associations with clinical symptoms in deficit schizophrenia (DS) and non-deficit schizophrenia (NDS). Pyrosequencing and RT-qPCR were separately used to determine DNA methylation and mRNA expression of CXCL1 gene. Both DNA methylation and expression were significantly different among DS, NDS and healthy control (HC) groups. Correlation analysis revealed that CXCL1 gene expression was associated with the negative syndrome in NDS patients, while no association in DS patients was observed...
July 4, 2018: Psychiatry Research
Jean-Arthur Micoulaud-Franchi, Mélanie Faugere, Sebastien Weibel, Catherine Faget, Christophe Lancon, Raphaëlle Richieri, Michel Cermolacce
The severity of depressive symptoms across two discrete mental disorders should be evaluated with the same psychometrically validated tools. In patients with schizophrenia the Calgary Depression Rating Scale (CDSS) is recommended for evaluating depressive symptoms. The aim of this study was to validate the CDSS in patients with major depressive disorder. The CDSS exhibit satisfactory psychometric properties for evaluating depressive symptoms in major depressive disorder. Clinicians and researchers now have a validated scale at their disposal to evaluate depressive symptoms in various mental disorders using a transdiagnostic approach...
July 4, 2018: Psychiatry Research
Lindsay A Taliaferro, Barbara J McMorris, Marla E Eisenberg
We examined associations between social connections and non-suicidal self-injury (NSSI) among transgender/gender non-conforming (TGNC) youth. Data came from the 2016 Minnesota Student Survey (N = 2168). Logistic regression analyses determined connectedness factors associated with any past-year NSSI and repetitive NSSI, as well as moderating effects of significant connectedness factors on different risk factors. Almost 55% of TGNC students engaged in NSSI, and 40% of self-injurers reported repetitive self-injury...
July 4, 2018: Psychiatry Research
Rui Peng, Wen Dai, Yan Li
The proteomic study reported that Tenascin-C might be a diagnostic biomarker for major depressive disorder, but clinical studies of this potential relationship are lacking. Here we examined the association between tenascin-C levels in serum and suicide attempts. Serum tenascin-C concentrations were compared among depressive patients who had not attempted suicide (n = 86), patients who had attempted it (n = 43), and healthy controls (n = 109). All participants were aged between 18 and 68 years. The association between concentration and suicide attempts was assessed by multivariate analysis after adjusting for sociodemographics, lifestyle and health indicators...
July 4, 2018: Psychiatry Research
Philip Gorwood, Jasmina Mallet, Sylvie Lancrenon
Functional remission concerns only one third of schizophrenia patients who achieved symptomatic remission. We previously developed a scale devoted to functional remission, named the FROGS (Functional Remission Of General Schizophrenia). This instrument encompasses three clinically relevant dimensions. The aim of this study is to provide a threshold for functional remission relying on these three dimensions, and to compare its psychometric properties with other scales devoted to functional remission. We tested the characteristics of functional remission according to the FROGS...
July 3, 2018: Psychiatry Research
Madelon M E Riem, Emmy N E M Doedée, Suzanne C Broekhuizen-Dijksman, Eugenie Beijer
Previous research has found an association between insecure attachment and increased somatization in adults. However, the mechanisms underlying this association are unknown. In the present study, we examined whether the association between attachment insecurity and somatization in psychiatric patients diagnosed with medically unexplained somatic symptoms (MUSS) is mediated by mentalization deficits. Attachment security of 58 outpatients diagnosed with MUSS was measured with the Experiences in Social Relationships Questionnaire (ECR)...
June 30, 2018: Psychiatry Research
Mohamad El Haj, Marie Charlotte Gandolphe, Ahmed A Moustafa, Jean-Louis Nandrino
Korsakoff's syndrome (KS) has been associated with a difficulty to retrieve specific autobiographical memories. We investigated whether this difficulty can be alleviated after the retrieval of statements describing self-images. KS patients and control participants were recruited and asked to retrieve autobiographical memories after providing statements to the question "Who am I?" and after a control condition consisting of verbal fluency. Analysis showed higher autobiographical specificity in the "Who am I?" than in verbal fluency condition in both patients with KS and control participants...
June 30, 2018: Psychiatry Research
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