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Journal of Clinical Gastroenterology

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https://www.readbyqxmd.com/read/28520581/reply-to-accuracy-of-consecutive-fecal-calprotectin-measurements-to-predict-relapse-in-inflammatory-bowel-disease-patients
#1
Rocio Ferreiro-Iglesias, Manuel Barreiro-de Acosta, Juan E Dominguez-Munoz
No abstract text is available yet for this article.
May 17, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28492425/identifying-patient-and-provider-specific-gaps-in-care-among-patients-with-hepatitis-b
#2
Tatyana Kushner, Robert Lam, Daniel L Gray, David E Kaplan, Marina Serper
GOALS: To examine patient, provider, and health system barriers to clinical follow-up among US veterans with chronic hepatitis B virus (HBV). BACKGROUND: Studies have demonstrated deficiencies in clinical care and follow-up in HBV; however, patient, provider, and health-system barriers in non-Asian populations are understudied. STUDY: A retrospective cohort of 517 US veterans with chronic HBV at 3 diverse Veterans Affairs sites from 1999 to 2015...
May 10, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28489647/obesity-bariatric-surgery-and-crohn-s-disease
#3
Burton I Korelitz, Niket Sonpal, Judy Schneider, Arun Swaminath, Joseph Felder, Mitchell Roslin, Jeffrey Aronoff
BACKGROUND: Crohn's disease (CD) following bariatric surgery has been previously described. It is not clear whether the clinical entity is due to rapid metabolism of fat, change in the bacterial milieu of the bowel, the loss of defense mechanisms of the stomach, or even a coincidence. OBJECTIVES: To present observations which might serve to sort out these various etiologies. DESIGN: We present 5 cases of colitis, ileocolitis or enteritis, some with fistula formation, with clinical onset following bariatric surgery and add these to the 7 cases previously identified as CD reported elsewhere...
May 9, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28489646/aggressive-hydration-with-lactated-ringer-solution-in-prevention-of-postendoscopic-retrograde-cholangiopancreatography-pancreatitis
#4
Zhi-Feng Zhang, Zhi-Jun Duan
No abstract text is available yet for this article.
May 9, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28489645/portal-vein-thrombosis-in-cirrhosis
#5
Michael Loudin, Joseph Ahn
Portal vein thrombosis (PVT) in the cirrhotic population is a challenging clinical phenomenon requiring a nuanced management approach. Uncertainty exists regarding the clinical significance of PVT in the cirrhotic population because the data for PVT are based mainly on retrospective, small cohort studies. Therefore, strong recommendations regarding the optimal timing, modality, and duration of therapy for PVT in the cirrhotic population cannot be made. However, this review aims to summarize the current literature and provide stepwise guidance in diagnosing and managing PVT in patients with cirrhosis...
May 9, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28471937/coexistence-of-colorectal-adenomas-and-coronary-calcification-in-asymptomatic-men-and-women
#6
Kyung Eun Yun, Yoosoo Chang, Sanjay Rampal, Yiyi Zhang, Juhee Cho, Hyun-Suk Jung, Chan-Won Kim, Chul Jeong, Miguel Cainzos-Achirica, Di Zhao, Roberto Pastor-Barriuso, Hocheol Shin, Eliseo Guallar, Seungho Ryu
GOALS: Because of shared risk factors between clinically manifest cardiovascular disease and colorectal cancer, we hypothesized the coexistence of subclinical atherosclerosis measured by coronary artery calcium (CAC) and colorectal adenoma (CRA) and that these 2 processes would also share common risk factors. BACKGROUND: No study has directly compared the risk factors associated with subclinical coronary atherosclerosis and CRA. STUDY: This was a cross-sectional study using multinomial logistic regression analysis of 4859 adults who participated in a health screening examination (2010 to 2011; analysis 2014 to 2015)...
May 3, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28452828/telephone-encounters-predict-future-high-financial-expenditures-in-inflammatory-bowel-disease-patients-a-3-year-prospective-observational-study
#7
Benjamin Click, Alyce M Anderson, Claudia Ramos Rivers, Ioannis E Koutroubakis, Jana G Hashash, Michael A Dunn, Marc Schwartz, Jason Swoger, Arthur Barrie, Eva Szigethy, Miguel Regueiro, Robert E Schoen, David G Binion
BACKGROUND: Telephone activity is essential in management of complex chronic diseases including inflammatory bowel disease (IBD). Telephone encounters logged in the electronic medical record have recently been proposed as a surrogate marker of disease activity and impending health care utilization; however, the association between telephone calls and financial expenditures has not been evaluated. STUDY: We performed a 3-year prospective observational study of telephone encounters logged at a tertiary referral IBD center...
April 27, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28445236/risk-stratification-in-acute-variceal-bleeding-child-pugh-versus-model-for-end-stage-liver-disease
#8
Enric Reverter, Joan Genesca, Salvador Augustin, Juan G Abraldes
No abstract text is available yet for this article.
April 25, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28445235/recent-trends-in-the-epidemiology-of-hepatocellular-carcinoma-in-olmsted-county-minnesota-a-us-population-based-study
#9
Ju Dong Yang, Hager Ahmed Mohammed, William S Harmsen, Felicity Enders, Gregory J Gores, Lewis R Roberts
BACKGROUND/AIM: The epidemiology of hepatocellular carcinoma (HCC) has changed in the United States recently. The aim of this study is to evaluate the recent trends of HCC epidemiology in Olmsted County, MN. METHODS: Residents aged over 20 with newly diagnosed HCC were identified using the Rochester Epidemiology Project database. Clinical information was compared among patients diagnosed between 2000 and 2009 (era 1) and 2010 to 2014 (era 2). RESULTS: Over 1...
April 25, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28422774/squamous-cellular-carcinoma-antigen-serum-determination-as-a-biomarker-of-barrett-esophagus-and-esophageal-cancer-a-phase-iii-study
#10
Gemma Maddalo, Matteo Fassan, Romilda Cardin, Marika Piciocchi, Filippo Marafatto, Massimo Rugge, Giovanni Zaninotto, Caterina Pozzan, Carlo Castoro, Alberto Ruol, Alessandra Biasiolo, Fabio Farinati
GOAL: To evaluate the potential role of the determination of the immunocomplexed form of squamous cell carcinoma antigen [SCCA-immunoglobulin (Ig)M] for the screening of Barrett esophagus (BE) and esophageal adenocarcinoma (EAC). BACKGROUND: The cost-effectiveness of surveillance in BE is still debated and the use of biomarkers in screening and surveillance still not recommended. No information is available regarding SCCA-IgM determination in BE. STUDY: SCCA-IgM levels were determined (enzyme-linked immunosorbent assay) in 231 patients prospectively recruited, 71 with BE, 53 with EAC, and 107 controls, including 42 blood donors and 65 patients with gastroesophageal reflux...
April 18, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28394777/prognostic-significance-of-hemodynamic-and-clinical-stages-in-the-prediction-of-hepatocellular-carcinoma-methodological-issues
#11
Siamak Sabour
No abstract text is available yet for this article.
April 7, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28383303/early-hospital-readmissions-and-mortality-in-patients-with-decompensated-cirrhosis-enrolled-in-a-large-national-health-insurance-administrative-database
#12
Steven J Scaglione, Leanne Metcalfe, Stephanie Kliethermes, Ivan Vasilyev, Rebecca Tsang, Allyce Caines, Shaham Mumtaz, Vik Goyal, Asra Khalid, David Shoham, Talar Markossian, Amy Luke, Howard Underwood, Scott J Cotler
BACKGROUND: Patients with decompensated cirrhosis have high rates of morbidity and mortality and frequently require hospital admission. Few studies have examined early readmission as an indicator of 90 day and overall mortality. Analysis of large databases is needed to evaluate the association between early readmission and mortality in decompensated cirrhosis. METHODS: We analyzed 5 years of private, employer-based, health insurance claims data associated with HealthCare Services Corporation on 13...
April 5, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28375866/reply-to-risk-stratification-in-acute-variceal-bleeding-child-pugh-versus-model-for-end-stage-liver-disease
#13
Brett E Fortune, Maria Ciarleglio, Yanhong Deng, Guadalupe Garcia-Tsao
No abstract text is available yet for this article.
April 3, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28375865/aggressive-hydration-for-the-prevention-of-post-ercp-pancreatitis-effective-when-combined-with-rectal-nsaids
#14
Xavier J N M Smeets, Joost P H Drenth, Erwin J M van Geenen
No abstract text is available yet for this article.
April 3, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28375864/risk-factors-for-asparaginase-associated-pancreatitis-a-systematic-review
#15
Judy-April Oparaji, Fateema Rose, Debra Okafor, Amari Howard, Rose L Turner, Abrahim I Orabi, Craig Byersdorfer, Qi Mi, Kim Ritchey, Mark E Lowe, Sohail Z Husain
GOALS: To evaluate potential risk factors for the development of asparaginase-associated pancreatitis (AAP), we performed a systematic review of the current literature from January 1946 through May 2015. BACKGROUND: Asparaginase, a primary treatment for the most common childhood cancer, acute lymphoblastic leukemia (ALL), is a well-described cause of pancreatitis. Further, pancreatitis is among the most burdensome and common complications of asparaginase treatment and represents a major reason for early-drug termination and inferior outcomes...
April 3, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28362682/genetic-determinants-of-circulating-lipoproteins-in-nonalcoholic-fatty-liver-disease
#16
Zhenghui G Jiang, Elliot B Tapper, Misung Kim, Margery A Connelly, Sarah A Krawczyk, Eric U Yee, Mark A Herman, Kenneth J Mukamal, Michelle Lai
BACKGROUND: Recent genome-wide association studies have identified 2 genetic polymorphisms in association with nonalcoholic fatty liver disease (NAFLD): patatin-like phospholipase domain containing 3 (PNPLA3) and transmembrane 6 superfamily member 2 (TM6SF2), both of which appear to influence the production of very low density lipoprotein (VLDL). The impact of these genetic variations on lipoprotein metabolism in the setting of nonalcoholic steatohepatitis and liver fibrosis are not fully characterized...
March 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28323748/serum-aminotransferase-flares-in-pregnant-and-postpartum-women-with-current-or-prior-treatment-for-chronic-hepatitis-b
#17
Christine Y Chang, Natali Aziz, Mugilan Poongkunran, Asad Javaid, Huy N Trinh, Daryl T Lau, Mindie H Nguyen
BACKGROUND AND AIMS: Antiviral therapy is recommended for pregnant women with chronic hepatitis B (CHB) and hepatitis B virus (HBV) DNA>200,000 IU/mL, but there is less consensus on management of women who discontinue therapy in anticipation of pregnancy or who become pregnant while on therapy. The goal of this study was to describe flares in alanine aminotransferase (ALT) during pregnancy and postpartum in CHB women with current and/or prior treatment. METHODS: This was a multicenter, retrospective study of 67 pregnancies in 56 CHB women treated before and/or during pregnancy...
March 20, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28296656/severity-and-outcome-of-acute-on-chronic-liver-failure-is-dependent-on-the-etiology-of-acute-hepatic-insults-analysis-of-368-patients
#18
Shalimar, Saurabh Kedia, Soumya J Mahapatra, Baibaswata Nayak, Deepak Gunjan, Bhaskar Thakur, Subrat K Acharya
BACKGROUND: Acute-on-chronic liver failure (ACLF) may be precipitated by various hepatic insults. The present study evaluated the outcomes of ACLF with different acute insults. PATIENTS AND METHODS: A total of 368 ACLF patients were included. Data collected included etiologies of acute hepatic insult and underlying chronic liver disease, and organ failure. Model for end-stage liver disease (MELD), chronic liver failure consortium (CLIF)-C ACLF, and acute physiology and chronic health evaluation (APACHE) II scores were calculated...
March 14, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28291175/ppi-trial-for-eosinophilic-esophagitis-chaos-in-the-community
#19
Seth Lipka, Ambuj Kumar, Joel E Richter
INTRODUCTION: Despite consensus eosinophilic esophagitis (EoE) statement published in 2011 calling for a 2-month trial of protons pump inhibitor (PPI), the guidelines are not followed by many. We studied the practice patterns in our community and response to a PPI retrial in patients previously diagnosed with "idiopathic EoE." METHODS: All patients presenting to the senior author's practice with suspected EoE from 2011 to 2015. Two cohorts were studied: (1) patients diagnosed in the community as "idiopathic EoE"; (2) treatment naïve patients given a PPI trial at University of South Florida...
March 13, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28277375/potential-pitfalls-when-assessing-the-impact-of-cytomegalovirus-in-inflammatory-bowel-disease
#20
Jeffrey D McCurdy, David H Bruining, Edward V Loftus
No abstract text is available yet for this article.
March 8, 2017: Journal of Clinical Gastroenterology
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