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Journal of Clinical Gastroenterology

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https://www.readbyqxmd.com/read/29351157/association-between-cotinine-verified-smoking-status-and-risk-of-colorectal-neoplasia
#1
Nam Hee Kim, Yoon Suk Jung, Hyo-Joon Yang, Soo-Kyung Park, Jung Ho Park, Dong Il Park, Chong Il Sohn
GOALS: We evaluated the association of urinary cotinine-verified smoking status with the risk of colorectal neoplasia (CRN). BACKGROUND: Many studies have reported the association between the risk of CRN and smoking status, based on self-reported questionnaires. Although self-reported smoking status may be inaccurate, to our knowledge, no study has yet assessed the association between objective biomarkers of tobacco exposure and the risk of CRN. STUDY: A cross-sectional study was conducted on 96,806 asymptomatic examinees who underwent colonoscopy and urinary cotinine measurements as part of a health check-up...
January 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29351156/liquid-nitrogen-spray-cryotherapy-is-associated-with-less-postprocedural-pain-than-radiofrequency-ablation-in-barrett-s-esophagus-a-multicenter-prospective-study
#2
Sanjeev S Solomon, Shivangi Kothari, George B Smallfield, Sumant Inamdar, Peter Stein, Viviana A Rodriguez, Adam P Sima, Krystle Bittner, Alvin M Zfass, Vivek Kaul, Arvind J Trindade
GOALS AND BACKGROUND: Two common endoscopic therapies for eradication of dysplastic Barrett's esophagus are radiofrequency ablation (RFA) and liquid nitrogen spray cryotherapy (LNC). There is no data comparing postprocedural pain. This study aimed to compare the incidence of postprocedural pain between the 2 ablation modalities. METHODS: This is a multicenter prospective study in which pain intensity scores and the presence of dysphagia were assessed immediately before and after treatment, 48 hours posttreatment and at 3 weeks posttreatment using validated instruments...
January 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29351155/inpatient-outcomes-for-gastrointestinal-bleeding-associated-with-percutaneous-coronary-intervention
#3
George Cholankeril, Menghan Hu, Rosann Cholankeril, Muhammad A Khan, Chiran Gadiparthi, Eric R Yoo, Ryan B Perumpail, Satheesh Nair, Colin W Howden
GOALS: The goal of this study was to evaluate the impact of inpatient outcomes of gastrointestinal bleeding (GIB) related to percutaneous coronary intervention (PCI). BACKGROUND: With all-cause mortality increasing in patients undergoing PCIs, outcomes for GIB associated with PCI may be adversely impacted. STUDY: Using the National Inpatient Sample (2007 to 2012), we performed a nested case-control study assessing inpatient outcomes including incidence and mortality for PCI-related GIB hospitalizations...
January 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29351154/predictors-of-health-related-quality-of-life-in-irritable-bowel-syndrome-patients-compared-with-healthy-individuals
#4
Raymond Addante, Bruce Naliboff, Wendy Shih, Angela P Presson, Kirsten Tillisch, Emeran A Mayer, Lin Chang
BACKGROUND: Irritable bowel syndrome (IBS) reduces health-related quality of life (HRQOL). It is unclear how having IBS modifies the impact of gastrointestinal (GI), psychosocial, and somatic symptom variables on HRQOL compared with healthy controls (HCs). AIMS: (1) Determine psychosocial, somatic, and physical status variables most predictive of HRQOL in IBS and HCs and (2) determine if IBS status modifies relationships between predictive factors and HRQOL. METHODS: IBS patients and HCs completed validated questionnaires measuring GI symptoms, psychosocial/somatic variables, and physical [physical component score (PCS)] and mental [mental component score (MCS)] HRQOL via the Short-Form-36...
January 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29334502/risk-of-hepatitis-b-virus-reactivation-among-patients-treated-with-ledipasvir-sofosbuvir-for-hepatitis-c-virus-infection
#5
Beshoy T Yanny, Nyan L Latt, Sammy Saab, Steven Han, Gina Choi, Jason Kramer, Amandeep K Sahota
BACKGROUND: Direct acting antiviral (DAA) agents are the standard of care for treatment of hepatitis C virus (HCV)-infected individuals. Hepatitis B virus (HBV) reactivation during HCV treatment has been reported, the incidence and clinical outcome remains unclear. The aim of our study is to examine the risk of HBV reactivation in actively infected or previously exposed patients during or after HCV treatment with DAAs. METHODS: Adults with chronic HCV infection previously exposed or actively infected with HBV and treated with DAAs between December 2015 to 2016 were included...
January 12, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29283905/efficacy-and-safety-of-flexible-endoscopic-management-of-zenker-s-diverticulum
#6
Deepanshu Jain, Abhinav Sharma, Manan Shah, Upen Patel, Nirav Thosani, Shashideep Singhal
Zenker's diverticulum (ZD), a pulsion diverticulum of hypopharynx is a rare but treatable cause of morbidity in geriatric population. Traditionally a surgical disease but due to its associated high morbidity, flexible endoscopy has become a lucrative option. We reviewed 997 patients from 23 original studies who underwent flexible endoscopic diverticulotomy (FED) of ZD. Composite technical and clinical success rate for the study cohort was 99.4% and 87.9%, respectively. Composite failure rate was 10.0% but close to half of them (45...
December 27, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29283904/role-of-full-spectrum-endoscopy-in-colorectal-cancer-screening-randomized-trial
#7
Henar Núñez-Rodríguez, Pilar Diez-Redondo, Manuel Pérez-Miranda, Manuel Gonzalez Sagrado, Rosa Conde, Carlos De la Serna
GOALS: The aim of this study was to compare a new, full-spectrum endoscope (Fuse; EndoChoice, Alpharetta, GA) to standard forward-viewing colonoscopy in the detection of colorectal neoplasms. BACKGROUND: Colonoscopy, the gold standard for the detection of colorectal cancer, fails to detect 22% to 28% of polyps, increasing the risk of interval cancer. Endoscopic improvement of the adenoma detection rate decrease interval carcinomas. Full-spectrum endoscopy (FUSE) (330-degree field of view), in a tandem study, has been shown to reduce the adenoma miss rate...
December 27, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29256992/an-update-on-current-management-strategies-for-achalasia-and-future-perspectives
#8
Ioana Smith, Michel Kahaleh
The last decade has seen growing insight into the pathophysiology of achalasia, and current treatments decreasing the resting pressure in the lower esophageal sphincter by endoscopic (botulinum toxin injection, pneumatic dilation, peroral endoscopic myotomy) or surgical means (Heller myotomy). Manometry is considered the gold standard to confirm the diagnosis of achalasia. Pneumatic dilation and laparoscopic Heller myotomy have similar effectiveness and are both more successful in patients with type II achalasia...
December 18, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29256991/fecal-matrix-metalloproteinase-9-measurement-for-optimizing-detection-of-disease-activity-in-inflammatory-bowel-disease
#9
Joany E Kreijne, Janine van der Giessen, Auke P Verhaar, Maikel M Peppelenbosch, Annemarie C de Vries, Janneke C van der Woude, Gwenny M Fuhler
No abstract text is available yet for this article.
December 18, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29256990/emergency-department-burden-of-gastroparesis-in-the-united-states-2006-to-2013
#10
William Hirsch, Judy Nee, Sarah Ballou, Travis Petersen, Daniel Friedlander, Ha-Neul Lee, Vivian Cheng, Anthony Lembo
BACKGROUND AND AIMS: Gastroparesis, a chronic gastrointestinal disorder defined by delayed stomach emptying in the absence of obstruction, is often associated with frequent and costly visits to the emergency department (ED). The aim of this study was to analyze trends in gastroparesis-related ED visits from 2006 to 2013. MATERIALS AND METHODS: Patients with a primary diagnosis of gastroparesis were identified from the Nationwide Emergency Department Sample (NEDS), the largest publicly available ED all-payer representative database in the United States...
December 18, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29256989/diagnostic-yield-of-2-strategies-for-adult-celiac-disease-identification-in-primary-care
#11
Riccardo Scoglio, Gianluca Trifirò, Antonino Sandullo, Giovanni Marangio, Cinzia D'Agate, Stefano Costa, Salvatore Pellegrino, Angela Alibrandi, Andrea Aiello, Giovanni Currò, Chiara Cuzzupè, Fabrizio Comisi, Salvatore Amato, Roberto Conti Nibali, Sergio Oteri, Giuseppe Magazzu, Antonio Carroccio
GOALS: To compare the diagnostic yield and cost-consequences of 2 strategies, screening regardless of symptoms versus case finding (CF), using a point-of-care test (POCT), for the detection of celiac disease (CD) in primary care, to bridge the diagnostic gap of CD in adults. MATERIALS AND METHODS: All subjects under 75 years of age who consecutively went to their general practitioners' offices were offered POCT for anti-transglutaminase immunoglobulin A antibodies...
December 18, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29252684/trends-in-hospitalization-acute-kidney-injury-and-mortality-in-patients-with-spontaneous-bacterial-peritonitis
#12
Kalpit Devani, Paris Charilaou, Palashkumar Jaiswal, Nirav Patil, Dhruvil Radadiya, Pranav Patel, Mark Young, Don C Rockey, Chakradhar M Reddy
GOALS: The purpose of our study was to evaluate trends of hospitalization, acute kidney injury (AKI) and mortality in cirrhotic patients with spontaneous bacterial peritonitis (SBP). BACKGROUND: SBP is a frequent bacterial infection in cirrhotic patients leading to increased morbidity and mortality. MATERIALS AND METHODS: A total of 4,840,643 patients hospitalized with cirrhosis from 2005 to 2014 were identified using the Nationwide Inpatient Sample database, of which 115,359 (2...
December 15, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29206754/abdominal-ultrasound-does-not-reveal-significant-alterations-in-patients-with-nonceliac-wheat-sensitivity
#13
Maurizio Soresi, Pasquale Mansueto, Antonino Terranova, Alberto D'Alcamo, Francesco La Blasca, Francesca Cavataio, Rosario Iacobucci, Antonio Carroccio
GOALS: The goal of this study was (A) to evaluate abdominal ultrasound signs in nonceliac wheat sensitivity (NCWS) patients for features useful in diagnosis and (B) to compare these aspects with those of celiac patients to assess whether ultrasound can be useful in the differential diagnosis between NCWS and celiac disease (CD). BACKGROUND: NCWS diagnosis is difficult as no biomarkers of this condition have as yet been identified. In CD ultrasound aspects have been identified that have a good diagnostic accuracy...
December 4, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29206753/the-effects-of-sleep-on-the-commensal-microbiota-eyes-wide-open
#14
Parth J Parekh, Edward C Oldfield, David A Johnson
Sleep dysfunction is an epidemic, the implications of which have a profound impact on a variety of gastrointestinal disease. Recent data suggests a relationship between sleep dysfunction and intestinal dysbiosis, a known proinflammatory driver. This article evaluates the interplay between sleep dysfunction and gastrointestinal health and disease, with a focus on the impact of circadian rhythm disruption on the commensal microbiota.
December 4, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29206752/rather-than-surgical-technique-dedicated-stroke-centers-improve-bowel-and-life-outcomes-in-acute-mesenteric-ischemia
#15
Alexandre Nuzzo, Maxime Ronot, Leon Maggiori, Olivier Corcos
No abstract text is available yet for this article.
December 4, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29206751/the-impact-of-clostridium-difficile-infection-on-mortality-in-patients-with-inflammatory-bowel-disease-a-systematic-review-and-meta-analysis
#16
Raseen Tariq, Cindy C Y Law, Sahil Khanna, Sanjay Murthy, Jeffrey D McCurdy
BACKGROUND AND AIMS: Clostridium difficile infection (CDI) has been associated with an increased mortality risk among patients with inflammatory bowel disease (IBD) in multiple observational studies. We performed a systematic review and meta-analysis to help clearly define the magnitude of risk in IBD patients with and without CDI, and to assess the risk in individual IBD subtypes. METHODS: A systematic search of multiple electronic databases was conducted for observational studies reporting the risk of mortality in IBD, stratified by the presence of CDI...
December 4, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29210902/insufflation-with-carbon-dioxide-during-pediatric-colonoscopy-for-control-of-postprocedure-pain
#17
Chad Thornhill, Fernando Navarro, Baraa Alabd Alrazzak, S Shahrukh Hashmi, Ashish N DebRoy, Jon M Rhoads, Essam Imseis
GOALS: To determine if carbon dioxide (CO2) insufflation in children would improve postprocedure pain following colonoscopy in children. BACKGROUND: CO2 insufflation during colonoscopy has been found to reduce postcolonoscopy pain in the adult population, but limited data exist in pediatrics. MATERIALS AND METHODS: We conducted a prospective study with 40 pediatric patients scheduled for outpatient colonoscopy. Patients were enrolled continuously and were randomized to receive CO2 or air insufflation...
November 28, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29210901/smoking-habits-are-strongly-associated-with-colorectal-polyps-in-a-population-based-case-control-study
#18
Naomi Fliss-Isakov, Shira Zelber-Sagi, Muriel Webb, Zamir Halpern, Revital Kariv
GOALS: The goal of this study is to test the association between lifetime smoking habits and colorectal polyps of different classifications. BACKGROUND: Smoking is an established risk factor for several cancers, including colorectal cancer. However, the association between lifetime smoking habits including intensity, duration, and cessation, and premalignant colorectal polyps is yet to be established. STUDY: A case-control study among 828 consecutive subjects aged 40 to 70 years, undergoing screening or diagnostic colonoscopy...
November 28, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29210900/development-of-image-enhanced-endoscopy-of-the-gastrointestinal-tract-a-review-of-history-and-current-evidences
#19
Shiaw-Hooi Ho, Noriya Uedo, Akira Aso, Shuji Shimizu, Yutaka Saito, Kenshi Yao, Khean-Lee Goh
Endoscopy imaging of the gastrointestinal (GI) tract has evolved tremendously over the last few decades. Key milestones in the development of endoscopy imaging include the use of various dyes for chromoendoscopy, the application of optical magnification in endoscopy, the introduction of high-definition image capturing and display technology and the application of altered illuminating light to achieve vascular and surface enhancement. Aims of this review paper are to summarize the development and evolution of modern endoscopy imaging and in particular, imaged-enhanced endoscopy (IEE), to promote appropriate usage, and to guide future development of good endoscopy practice...
November 28, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29210899/distinct-microbial-populations-exist-in-the-mucosa-associated-microbiota-of-diarrhea-predominant-irritable-bowel-syndrome-and-ulcerative-colitis
#20
Wenting Zhong, Xiaolan Lu, Haitao Shi, Gang Zhao, Yahua Song, Yonghua Wang, Jing Zhang, Yaofeng Jin, Shenhao Wang
GOALS: The goal of this study was to observe the bacterial colonization in the intestinal mucosa in the patients with diarrhea predominant irritable bowel syndrome (IBS-D) and ulcerative colitis (UC), and compare the mucosa-associated microbiota among the IBS-D patients, UC patients and the healthy control, and explore the correlation of the mucosa-associated microbiota with clinical manifestations. STUDY: A total of 20 IBS-D patients, 28 patients with UC (16 active, 12 inactive) and 16 healthy subjects were enrolled in the study...
November 28, 2017: Journal of Clinical Gastroenterology
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