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Journal of Clinical Gastroenterology

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https://www.readbyqxmd.com/read/28906426/meld-stratified-outcomes-among-recipients-with-diabetes-or-hypertension-simultaneous-liver-kidney-versus-liver-alone
#1
Ashwani K Singal, Mohsen Hasanin, Mohamed Kaif, Russell W Wiesner, Yong-Fang Kuo
BACKGROUND AND AIM: Data are scanty on allocating simultaneous liver kidney (SLK) based on model for end-stage disease (MELD) score. Diabetes mellitus (DM) and hypertension (HTN) are frequent in cirrhosis patients. We analyzed transplant recipients with DM and/or HTN to compare MELD-based outcomes of SLK to liver transplantation alone (LTA). MATERIALS AND METHODS: Of 13,584 first deceased donor liver transplantation among patients with DM and/or HTN (1530 or 11...
September 12, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28906425/impact-of-changeover-to-newer-endoscopic-systems-on-quality-and-efficiency-of-screening-and-surveillance-colonoscopy-equipment-or-endoscopist
#2
Manpreet Singh, Melody Sacatos, Loren Laine
GOALS: The goal of this study is to assess whether changeover to newer endoscopic systems impacts quality or efficiency, and quantify the relation between increased withdrawal time and detection rates of sessile serrated polyps (SSPDR) and adenomas (ADR) in real-world practice. STUDY: Beginning 2 months after new endoscopic systems were implemented at 2 endoscopy units, we included all outpatients undergoing screening/surveillance colonoscopy for 4 months. Outpatients during the same 4-month period 1 year earlier comprised the control group...
September 12, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28906424/accurate-identification-of-colonoscopy-quality-and-polyp-findings-using-natural-language-processing
#3
Jeffrey K Lee, Christopher D Jensen, Theodore R Levin, Ann G Zauber, Chyke A Doubeni, Wei K Zhao, Douglas A Corley
OBJECTIVES: The aim of this study was to test the ability of a commercially available natural language processing (NLP) tool to accurately extract examination quality-related and large polyp information from colonoscopy reports with varying report formats. BACKGROUND: Colonoscopy quality reporting often requires manual data abstraction. NLP is another option for extracting information; however, limited data exist on its ability to accurately extract examination quality and polyp findings from unstructured text in colonoscopy reports with different reporting formats...
September 12, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28885305/successful-esophageal-dilation-of-eosinophilic-esophagitis-eoe-patients-with-a-previous-postdilation-complication-start-low-and-go-slow
#4
Seth Lipka, Ambuj Kumar, Joel E Richter
INTRODUCTION: Esophageal dilation is an effective and safe treatment option for fibrostenotic eosinophilic esophagitis (EoE). Despite the safety, adverse events occur, yet there is scarce literature on the best treatment postcomplications. METHODS: Patients with diagnosis of EoE (≥15 eosinophils per high-power field) from 2011 to 2015 treated at our center were included. Thirty patients with fibrostenotic disease had records available regarding serial dilation therapy...
September 6, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28885304/bowel-preparations-administered-the-morning-of-colonoscopy-provide-similar-efficacy-to-a-split-dose-regimen-a-meta-analysis
#5
Danny J Avalos, Fernando J Castro, Marc J Zuckerman, Tara Keihanian, Andrew C Berry, Benjamin Nutter, Daniel A Sussman
BACKGROUND: Comparative efficacy of same-day bowel preparations for colonoscopy remains unclear. AIMS: A meta-analysis of randomized controlled trials comparing the efficacy of same-day versus split dose bowel preparations for colonoscopy. METHODS: A systematic search was conducted in MEDLINE, clinicaltrials.gov, Cochrane Registry, EMBASE, SCOPUS, Web of Science and CINAHL. Studies were gathered using keywords: "morning preparation", "morning bowel preparation", "same day bowel preparation", and "colonoscopy...
September 6, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28885303/validation-of-probe-based-confocal-laser-endomicroscopy-pcle-criteria-for-diagnosing-colon-polyp-histology
#6
Sreekar Vennelaganti, Prashanth Vennalaganti, Sharad Mathur, Satish Singh, Mazen Jamal, Vijay Kanakadandi, Tarun Rai, Matthew Hall, Neil Gupta, Venkat Nutalapati, Benjamin Alsop, Benjamin Hornung, Prateek Sharma
BACKGROUND: Validated probe-based confocal endomicroscopy (pCLE) criteria for distinguishing hyperplastic polyps (HPs) and tubular adenomas (TA) have not yet been developed. AIM: To develop pCLE criteria for distinguishing HP from TA and evaluate its performance characteristics among experts. METHODS: pCLE criteria for colon polyp histology were developed and tested in 2 phases prospectively. Phase I: 8 preliminary criteria were developed and tested internally...
September 6, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28885302/postinfection-irritable-bowel-syndrome-the-links-between-gastroenteritis-inflammation-the-microbiome-and-functional-disease
#7
Ian A Downs, Olga C Aroniadis, Libusha Kelly, Lawrence J Brandt
Postinfection irritable bowel syndrome (PI-IBS) is a diarrheal disease that develops after infectious gastroenteritis (IGE). Profound alterations in the microbiota accompany IGE yet only 10% of IGE patients progress to PI-IBS. This review explores research linking IGE severity, psychological comorbidity, PI-IBS, and the microbiome in various patient populations. Selective pressures caused by inflammation and increased gastrointestinal motility during gastroenteritis can alter intestinal bacterial phyla including Bacteroidetes, Firmicutes, and Proteobacteria...
September 6, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28863014/antiviral-therapy-in-patients-with-chronic-hepatitis-c-related-hepatocellular-carcinoma-responding-to-palliative-treatment
#8
Jung-Hwan Yu, Ja Kyung Kim, Kwan Sik Lee, Jung Il Lee
BACKGROUND/AIM: Advances in hepatitis C virus (HCV) treatment offer high sustained virologic response rates with minimal side-effects. However, benefits of eradicating HCV in hepatocellular carcinoma (HCC) patients whose life expectancies are hard to be determined after palliative therapy still needs to be assessed. This study sought to evaluate prognostic factors for survival in HCV-related HCC patients that responded to the palliative HCC treatment to speculate whether treating HCV would be beneficial in these patients...
August 31, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28858947/is-transcutaneous-endoscopic-necrosectomy-appropriate-method-in-managing-all-patients-with-walled-off-pancreatic-necrosis-that-extend-into-the-paracolic-gutter
#9
Enver Zerem, Predrag Jovanović, Mirza Omerović, Dženan Jahić, Dina Zerem, Omar Zerem
No abstract text is available yet for this article.
August 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28858945/impact-of-insurance-status-and-race-on-outcomes-in-nonvariceal-upper-gastrointestinal-hemorrhage-a-nationwide-analysis
#10
Marwan S Abougergi, Patrick Avila, John R Saltzman
BACKGROUND AND GOALS: We examined the interaction between race, insurance, and important outcomes in nonvariceal upper gastrointestinal hemorrhage (NVUGIH). STUDY: Adults with NVUGIH were selected from the National Inpatient Sample. PRIMARY OUTCOME: in-hospital mortality. SECONDARY OUTCOMES: treatment modalities [esophagogastroduodenoscopy (EGD), early EGD, and endoscopic or radiologic therapy], and resource utilization (length of hospital stay and total hospitalization charges)...
August 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28858944/rate-of-nonsurveillance-and-advanced-hepatocellular-carcinoma-at-diagnosis-in-chronic-liver-disease
#11
Yi Huang, Michael C Wallace, Leon A Adams, Gerry MacQuillan, George Garas, John Ferguson, Shaun Samuelson, Jonathan Tibballs, Gary P Jeffrey
AIMS: Ultrasound surveillance for hepatocellular carcinoma (HCC) is recommended in cirrhotic patients to allow early diagnosis. This study investigated risk factors for nonsurveillance and advanced HCC at diagnosis and their effect on survival. MATERIALS AND METHODS: Two hundred seventy HCC patients were included. Clinical data were collected from hospital databases. RESULTS: One hundred twenty-eight (47.1%) patients had 6-monthly ultrasound surveillance before HCC diagnosis...
August 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28858943/increased-risk-of-mortality-associated-with-pancreatic-exocrine-insufficiency-in-patients-with-chronic-pancreatitis
#12
Daniel de la Iglesia-Garcia, Nicolau Vallejo-Senra, Julio Iglesias-Garcia, Andrea López-López, Laura Nieto, J Enrique Domínguez-Muñoz
BACKGROUND: Pancreatic exocrine insufficiency (PEI) is a common serious complication in chronic pancreatitis (CP); however, little is known about its effect on mortality in these patients. In this study, we assessed the mortality risk of PEI in patients with CP. STUDY: A prospective, longitudinal cohort study conducted in patients with CP under long-term follow-up. CP and PEI were diagnosed using pancreatic imaging and the C-labeled mixed triglyceride breath test, respectively...
August 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28858942/colonoscopy-in-patients-with-postmyocardial-infarction-gastrointestinal-bleeding-a-nationwide-analysis
#13
Rohan M Modi, Feng Li, Khalid Mumtaz, Alice Hinton, Scott M Lilly, Hisham Hussan, Edward Levine, Cheng Zhang, Darwin L Conwell, Somashekar G Krishna, Peter P Stanich
GOALS: The goal of this study was to evaluate outcomes of colonoscopy in the setting of post myocardial infarction (MI) gastrointestinal bleeding (GIB) in a large population-based data set. BACKGROUND: The literature to substantiate the proposed safety of colonoscopy following an acute MI is limited. STUDY: The Nationwide Inpatient Sample (2007 to 2013) was utilized to identify all adult patients (age, 18 y or above) hospitalized with a primary diagnosis of ST-elevation MI and receiving left heart catheterization (STEMI-C)...
August 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28858941/regional-and-national-variations-in-reasons-for-gluten-avoidance
#14
Haley M Zylberberg, Shireen Yates, Carla Borsoi, Peter H R Green, Benjamin Lebwohl
BACKGROUND: Although studies have assessed the prevalence of celiac disease (CD), less is known about the prevalence of gluten avoidance because of nonceliac gluten sensitivity (GS). The avoidance of foods other than gluten is also understudied in these 2 groups. METHODS: Participants visiting a web site for information about a newly developed portable gluten detection device (Nima) were instructed to complete questions about food and gluten avoidance patterns. We assessed the relative proportion of CD and GS across world regions and United States (US) regions and determined the distribution of food avoidance patterns...
August 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28858940/fat-soluble-vitamin-deficiencies-and-inflammatory-bowel-disease-systematic-review-and-meta-analysis
#15
Natalia Fabisiak, Adam Fabisiak, Cezary Watala, Jakub Fichna
BACKGROUND: Vitamin deficiency is frequently associated with inflammatory bowel disease (IBD). Supplementation of vitamins could thus serve as an adjunctive therapy. The present meta-analysis reviews the deficiencies and alterations in serum fat-soluble vitamins (A, D, E, and K) reported in IBD patients. MATERIALS AND METHODS: PubMed database search was performed to identify all primary studies up to January 2015 that evaluated the serum concentrations of fat-soluble vitamin levels in IBD patients compared with healthy individuals...
August 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28858939/beyond-abdominal-pain-pain-beliefs-pain-affect-and-distress-as-determinants-of-quality-of-life-in-patients-with-chronic-pancreatitis
#16
Craig E Keller, Charles Mel Wilcox, Gregory D Gudleski, Stacey Branham, Jeffrey M Lackner
GOALS: To assess the relationship between pain, psychological processes, and quality of life (QOL) in chronic pancreatitis (CP). BACKGROUND: CP is a progressive inflammatory disorder of the pancreas characteristically resulting in abdominal pain and impairing QOL. Pain due to CP is poorly understood and frequently difficult to treat. This pain has historically been understood as a peripheral process originating from the pancreas itself, but a growing body of literature is revealing an important role offered by central influences...
August 30, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28817457/a-comparison-by-meta-analysis-of-papillary-early-gastric-carcinoma-to-its-tubular-counterpart-for-the-risk-of-lymph-node-metastasis-and-submucosal-invasion
#17
Xiao-Yong Wang, Jin Yan, Jia Wu, Yi-Feng Zhang, Guo-Xin Zhang
BACKGROUND AND AIM: At present, the decision to perform endoscopic resection for treating either papillary early gastric cancer (EGC) or tubular EGC is made according to identical criteria. However, there is controversy in the literature whether the risk of lymph node metastasis (LNM) and submucosal invasion for both disease modalities is equal, and this prompts investigation to clarify this issue. METHODS: The PubMed and Web of Science databases were searched for relevant studies published up to January 2017...
August 16, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28795997/celecoxib-induced-liver-injury-analysis-of-published-case-reports-and-cases-reported-to-the-food-and-drug-administration
#18
Pavan K Mukthinuthalapati, Robert J Fontana, Raj Vuppalanchi, Naga Chalasani, Marwan Ghabril
BACKGROUND: Celecoxib is a widely prescribed nonsteroidal anti-inflammatory drug, and has been associated with rare instances of idiosyncratic drug-induced liver injury (DILI). The aim of this study is to describe and analyze the salient features of published cases of celecoxib DILI. MATERIALS AND METHODS: A literature search using common terms for liver injury cross-referenced with celecoxib was undertaken from the year 2000 through June 2016. Identified cases were analyzed with respect to reported demographic and clinical data with descriptive...
August 8, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28795996/initial-alpha-fetoprotein-response-predicts-prognosis-in-hepatitis-b-related-solitary-hcc-patients-after-radiofrequency-ablation
#19
Su Jong Yu, Jee Hye Kwon, Won Kim, Jung-Hwan Yoon, Jeong Min Lee, Jae Young Lee, Eun Ju Cho, Jeong-Hoon Lee, Hwi Young Kim, Yong Jin Jung, Yoon Jun Kim
BACKGROUND: Radiofrequency ablation (RFA) is effective for early-stage hepatocellular carcinoma but recurrence is problem. GOALS: To identify prognostic factors including alpha-fetoprotein (AFP) for overall survival and intrahepatic recurrence after RFA. PATIENTS AND METHODS: Not only naïve but also previously treated patients with solitary hepatitis B virus-related hepatocellular carcinoma <5 cm were prospectively enrolled and a ≥50% decrease from baseline to 1 month after RFA was defined as an initial AFP response...
August 8, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28787362/an-adjusted-level-of-adenoma-detection-rate-is-necessary-for-adults-below-50-years-old
#20
Jin Young Yoon, Jae Myung Cha, Jeong Eun Shin, Kyeong Ok Kim, Hyo-Joon Yang, Hyun Gun Kim, Young-Seok Cho, Sun-Jin Boo, Jun Lee, Yunho Jung, Hyun Jung Lee, Hoon Sup Koo, Young-Eun Joo
BACKGROUND: Although adenoma prevalence is lower in younger people compared with screening-aged adults 50 years old and above, there is no adjustment recommendation for the target adenoma detection rate (ADR) in young people. Herein, we estimated a different target ADR for adults below 50 years old based on screening colonoscopy findings. MATERIALS AND METHODS: Asymptomatic, average-risk adults below 50 years old who underwent screening colonoscopy were enrolled at 12 endoscopy centers in Korea between February 2006 and March 2012...
August 4, 2017: Journal of Clinical Gastroenterology
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