journal
MENU ▼
Read by QxMD icon Read
search

Journal of Biomechanical Engineering

journal
https://www.readbyqxmd.com/read/28639682/introduction-to-force-dependent-kinematics-theory-and-application-to-mandible-modeling
#1
Andersen Michael S, de Zee Mark, Damsgaard Michael, Nolte Daniel, Rasmussen John
Knowledge of the muscle, ligament and joint forces is important when planning orthopedic surgeries. Since these quantities cannot be measured in vivo under normal circumstances, the best alternative is to estimate them using musculoskeletal models. These models typically assume idealized joints, which are sufficient for general investigations but insufficient if the joint in focus is far from an idealized joint. The purpose of this study was to provide the mathematical details of a novel musculoskeletal modelling approach, called Force-dependent Kinematics (FDK), capable of simultaneously computing muscle, ligament and joint forces as well as internal joint displacements governed by contact surfaces and ligament structures...
June 22, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28633165/investigation-of-biotransport-in-a-tumor-with-uncertain-material-properties-using-a-non-intrusive-spectral-uncertainty-quantification-method
#2
Alen Alexanderian, Liang Zhu, Maher Salloum, Ronghui Ma, Meilin Yu
In this study, statistical models are developed for modeling uncertain heterogeneous permeability and porosity in tumors, and the resulting uncertainties in pressure and velocity fields during an intratumoral injection are quantified using a non-intrusive spectral uncertainty quantification (UQ) method. Specifically, the uncertain permeability is modeled as a log-Gaussian random field, represented using a truncated Karhunen-Loeve (KL) expansion, and the uncertain porosity is modeled as a log-normal random variable...
June 20, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28633164/ann-prediction-of-ligament-stiffnesses-for-the-enhanced-predictive-ability-of-a-patient-specific-computational-foot-ankle-model
#3
Ruchi Chande, Jennifer S Wayne
Computational models of diarthrodial joints serve to inform the biomechanical function of these structures, and as such, must be supplied appropriate inputs for performance that is representative of actual joint function. Inputs for these models are sourced from both imaging modalities as well as literature. The latter is often the source of mechanical properties for soft tissues, like ligament stiffnesses; however, such data is not always available for all soft tissues nor is it known for patient specific work...
June 20, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28617927/biomechanical-evaluations-of-injury-risk-for-blast-loading
#4
Bahram Notghi, Rajneesh Bhardwaj, Shantanu Bailoor, Kimberly Thompson, Ashley A Weaver, Joel D Stitzel, Thao Vicky Nguyen
Ocular trauma is one of the most common types of combat injuries resulting from the exposure of military personnel with improvised explosive devices. The injury mechanism associated with the primary blast wave are poorly understood. We employed a three-dimensional computational model, which included the main internal ocular structures of the eye, spatially varying thickness of the cornea-scleral shell, and nonlinear tissue properties, to calculate the intraocular pressure and stress state of the eye-wall and internal ocular structure caused by blast...
June 15, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28617909/development-of-a-flow-evolution-network-model-for-the-stress-strain-behavior-of-poly-l-lactide
#5
Maureen L Dreher, Srinidhi Nagaraja, Jorgen Bergstrom, Danika Hayman
Computational modeling is critical to medical device development and has grown in its utility for predicting device performance. Additionally, there is an increasing trend to use absorbable polymers for the manufacturing of medical devices. However, computational modeling of absorbable devices is hampered by a lack of appropriate constitutive models that capture their viscoelasticity and post-yield behavior. The objective of this study was to develop a constitutive model that incorporated viscoplasticity for a common medical absorbable polymer...
June 15, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28617908/validation-of-single-c-arm-biplane-fluoroscopy-system-for-in-vivo-measurement-of-porcine-abdominal-strains
#6
Lindsey G Kahan, Charlotte Guertler, Jeffrey A Blatnik, Spencer P Lake
Hernia meshes significantly reduce recurrence rates in hernia repair. It's known that they affect the abdominal wall post-implantation, yet the understanding of in vivo mechanics in the mesh placement area is lacking. We established a single c-arm biplane fluoroscopic system to study strains at the interface between the mesh and repaired abdominal tissues. We aimed to validate this system for future porcine hernia repair studies. Custom MATLAB programs were written to correct for pincushion distortion, and direct linear transformation reconstructed objects in 3D...
June 15, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28614573/finite-element-modeling-of-avascular-tumor-growth-using-a-stress-driven-model
#7
Faezeh Iranmanesh, Mohammad Ali Nazari
Tumor growth being a multi-stage process has been investigated from different aspects. In the present study, an attempt is made to represent a constitutive-structure based model of avascular tumor growth in which the effects of tensile stresses caused by collagen fibers are considered. Collagen fibers as a source of anisotropy in the structure of tissue, is taken into account using a continuous fiber distribution formulation. To this end, a finite element modeling is implemented in which a neo-Hookean hyperelastic material is assigned to the tumor and its surrounding host...
June 14, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28492928/local-changes-to-the-distal-femoral-growth-plate-following-injury-in-mice
#8
Lauren M Mangano Drenkard, Meghan E Kupratis, Katie Li, Louis C Gerstenfeld, Elise F Morgan
Injury to the growth plate is associated with growth disturbances, most notably premature cessation of growth. The goal of this study was to identify spatial changes in the structure and composition of the growth plate in response to injury to provide a foundation for developing therapies that minimize the consequences for skeletal development. We used contrast-enhanced micro-computed tomography (CECT) and histological analyses of a murine model of growth plate injury to quantify changes in the cartilaginous and osseous tissue of the growth plate...
May 8, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28464119/structural-and-chemical-modification-to-improve-adhesive-and-material-properties-of-fibrin-genipin-for-repair-of-annulus-fibrosus-defects-in-intervertebral-discs
#9
Michelle A Cruz, Steven McAnany, Nikita Gupta, Rose Long, Phillip R Nasser, David Eglin, Andrew Hecht, Svenja Illien-Junger, James C Iatridis
Annulus fibrosus (AF) defects from intervertebral disc herniation and degeneration are highly correlated with back pain. Genipin crosslinked fibrin hydrogel (FibGen) is an injectable, space-filling AF sealant that was optimized to match AF shear properties and partially restored disc biomechanics. This study enhanced mechanical behaviors of FibGen to more closely match AF compressive, tensile and shear properties by adjusting genipin crosslink density and by creating a composite formulation by adding Poly(D,L-lactide-co-glycolide) (PDLGA)...
May 2, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28462429/on-the-stiffness-of-the-mesh-and-urethral-mobility-a-finite-element-analysis
#10
Sofia Brandão, Marco Parente, Thuane Huyer Da Roza, Elisabete Silva, Isabel Maria Ramos, Teresa Mascarenhas, Renato Manuel Natal Jorge
Midurethral slings are used to correct urethral hypermobility in female stress urinary incontinence, defined as the complaint of involuntary urine leakage when the intra-abdominal pressure is increased. Structural and thermal features influence their mechanical properties, which may explain postoperative complications, e.g., erosion, urethral obstruction. We studied the effect of the mesh stiffness on urethral mobility at Valsalva maneuver, under impairment of the supporting structures (levator ani and/or ligaments), by using a numerical model...
May 2, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28462424/evaluation-of-a-surrogate-contact-model-in-multi-body-dynamic-simulations-of-total-knee-replacement
#11
Marco A Marra, Michael S Andersen, Michael Damsgaard, Bart F J M Koopman, Dennis Janssen, Nico Verdonschot
Knowing the forces in the human body is of great clinical interest and musculoskeletal models are the most commonly used tool to estimate them in vivo. Unfortunately, the process of computing muscle, joint contact and ligament forces simultaneously is computationally highly demanding. The goal of this study was to develop a fast surrogate model of the tibiofemoral (TF) contact in a total knee replacement (TKR) model and apply it to force-dependent kinematic simulations of activities of daily living (ADLs). Multiple domains were populated with sample points from the reference TKR contact model, based on reference simulations and design-of-experiments...
May 2, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28462423/design-and-validation-of-a-biosensor-implantation-capsule-robot
#12
Wanchuan Xie, Weston M Lewis, Jared Kaser, C Ross Welch, Pengbo Li, Carl A Nelson, Vishal Kothari, Benjamin S Terry
We have proposed a long-term, non-invasive, non-restrictive method of delivering and implanting a biosensor within the body via a swallowable implantation capsule robot (ICR). The design and preliminary validation of the ICR's primary subsystem-the sensor deployment system-is discussed and evidence is provided for major design choices. The purpose of the sensor deployment system is to adhere a small biosensor to the mucosa of the intestine long-term, and the modality was inspired by tapeworms and other organisms that employ a strategy of mechanical adhesion to soft tissue via the combined use of hooks or needles and suckers...
May 2, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28462417/non-uniform-moving-boundary-method-for-cfd-simulation-of-intrathecal-cerebrospinal-flow-distribution-in-a-cynomolgus-monkey
#13
Mohammadreza Khani, Tao Xing, Christina Gibbs, John Oshinski, Gregory R Stewart, Jillynne R Zeller, Bryn A Martin
A detailed quantification and understanding of cerebrospinal fluid (CSF) dynamics may improve detection and treatment of central nervous system (CNS) diseases and help optimize CSF system-based delivery of CNS therapeutics. This study presents a computational fluid dynamics (CFD) model that utilizes a non-uniform moving boundary approach to accurately reproduce the non-uniform distribution of CSF flow along the spinal subarachnoid space (SAS) of a single cynomolgus monkey. A magnetic resonance imaging (MRI) protocol was developed and applied to quantify subject-specific CSF space geometry and flow and define the CFD domain and boundary conditions...
May 2, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28418506/an-improved-optical-flow-method-for-blood-velocimetry
#14
Zifeng Yang, Hongtao Yu, George P Huang, Bryan Ludwig
Detailed blood velocity map in vascular system can be obtained by applying the optical flow method (OFM) in processing fluoroscopic digital subtracted catheter angiographic images, however, there are still challenges with the accuracy of this method. In the present study, a divergence compensatory Optical Flow Method (DC-OFM), in which a non-zero divergence of velocity is assumed due to the finite resolution of the image, was explored and applied to the digital subtraction angiography (DSA) images of blood flow...
April 17, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28418458/right-ventricular-fiber-structure-as-a-compensatory-mechanism-in-experimental-pressure-overload-a-computational-study
#15
Arnold D Gomez, Huashan Zou, Megan E Bowen, Xiaoqing Liu, Edward W Hsu, Stephen H McKellar
Right ventricular failure (RVF) is a lethal condition in diverse pathologies. Pressure overload is the most common etiology of RVF, but our understanding of the tissue structure remodeling and other biomechanical factors involved in RVF is limited. Some remodeling patterns are interpreted as compensatory mechanisms including myocyte hypertrophy, extracellular fibrosis, and changes in fiber orientation. However, the specific implications of these changes, especially in relation to clinically observable measurements, are difficult to investigate experimentally...
April 17, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28388735/a-novel-anterior-trans-pedicular-screw-artificial-vertebral-body-system-for-lower-cervical-spine-fixation-a-finite-element-study
#16
Weidong Wu, Chun Chen, Jinpei Ning, Pei-Dong Sun, Jinyuan Zhang, Changfu Wu, Zhenyu Bi, Jihong Fan, Xianliang Lai, Jun Ouyang
Objective A finite element model was used to compare the biomechanical properties of a novel anterior trans-pedicular screw artificial vertebral body system (AVBS) with a conventional anterior screw plate system (ASPS) for fixation in the lower cervical spine. Methods A model of the intact cervical spine (C3-C7) was established. AVBS or ASPS constructs were implanted between C4 and C6. The models were loaded in three-dimensional motion. The Von Mises stress distribution in the internal fixators was evaluated, as well as the range of motion (ROM) and facet joint force...
April 7, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28388715/separation-of-solid-stress-from-interstitial-fluid-pressure-in-pancreas-cancer-correlates-with-collagen-area-fraction
#17
Michael D Nieskoski, Kayla Marra, Jason R Gunn, Stephen C Kanick, Marvin M Doyley, Tayyaba Hasan, Stephen Pereira, B Stuart Trembly, Brian W Pogue
Elevated total tissue pressure in pancreatic adenocarcinoma is often associated with stress applied by cellular proliferation and hydrated hyaluronic acid osmotic swelling; however, the causal roles of collagen in total tissue pressure have yet to be clearly measured. This study illustrates one direct correlation between total tissue pressure and increased deposition of collagen within the tissue matrix. This observation comes from a new modification to a conventional piezoelectric pressure catheter, used to independently separate and quantify total tissue pressure, solid stress, and interstitial fluid pressure within the same tumor location, thereby clarifying the relationship between these parameters...
April 7, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28586917/toward-the-virtual-benchmarking-of-pneumatic-ventricular-assist-devices-application-of-a-novel-fluid-structure-interaction-based-strategy-to-the-penn-state-12-cc-device
#18
Alessandro Caimi, Francesco Sturla, Bryan Good, Marco Vidotto, Rachele De Ponti, Filippo Piatti, Keefe B Manning, Alberto Redaelli
The pediatric use of pneumatic ventricular assist devices (VADs) as a bridge to heart transplant still suffers for short-term major complications such as bleeding and thromboembolism. Although numerical techniques are increasingly exploited to support the process of device optimization, an effective virtual benchmark is still lacking. Focusing on the 12 cc Penn State pneumatic VAD, we developed a novel fluid-structure interaction (FSI) model able to capture the device functioning, reproducing the mechanical interplay between the diaphragm, the blood chamber, and the pneumatic actuation...
August 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28538996/the-relationship-between-surface-curvature-and-abdominal-aortic-aneurysm-wall-stress
#19
Sergio Ruiz de Galarreta, Aitor Cazón, Raúl Antón, Ender A Finol
The maximum diameter (MD) criterion is the most important factor when predicting risk of rupture of abdominal aortic aneurysms (AAAs). An elevated wall stress has also been linked to a high risk of aneurysm rupture, yet is an uncommon clinical practice to compute AAA wall stress. The purpose of this study is to assess whether other characteristics of the AAA geometry are statistically correlated with wall stress. Using in-house segmentation and meshing algorithms, 30 patient-specific AAA models were generated for finite element analysis (FEA)...
August 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28538985/numerical-approximation-of-elasticity-tensor-associated-with-green-naghdi-rate
#20
Haofei Liu, Wei Sun
Objective stress rates are often used in commercial finite element (FE) programs. However, deriving a consistent tangent modulus tensor (also known as elasticity tensor or material Jacobian) associated with the objective stress rates is challenging when complex material models are utilized. In this paper, an approximation method for the tangent modulus tensor associated with the Green-Naghdi rate of the Kirchhoff stress is employed to simplify the evaluation process. The effectiveness of the approach is demonstrated through the implementation of two user-defined fiber-reinforced hyperelastic material models...
August 1, 2017: Journal of Biomechanical Engineering
journal
journal
27769
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"