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Journal of Biomechanical Engineering

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https://www.readbyqxmd.com/read/28005133/formulation-of-generalised-mass-transfer-correlations-for-blood-oxygenator-design
#1
Kenny Wei Quan Low, Raoul van Loon, Sam Rolland, Johann Sienz
This paper numerically investigates non-Newtonian blood flow with oxygen and carbon dioxide transport across and along an array of uniformly square and staggered arranged fibres at various porosity (e) levels, focussing on a low Reynolds number regime (Re < 10). The objective is to establish suitable mass transfer correlations, expressed in the form of Sherwood number (Sh = f (e,Re,Sc)), that identifies the link from local mass transfer investigations to full-device analyses. The development of a concentration field is initially investigated and expressions are established covering the range from a typical deoxygenated condition up to a full oxygenated condition...
December 22, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28005132/biomechanical-phenotyping-of-the-murine-aorta-what-is-the-best-control
#2
Chiara Bellini, Alexander/W Caulk, Guangxin Li, George Tellides, Jay Humphrey
The availability of diverse mouse models is revealing increasingly greater information on arterial mechanics, including homeostatic adaptations and pathologic maladaptations to genetic, pharmacological, and surgical manipulations. Fundamental to understanding such biomechanical changes, however, is reliable information on appropriate control vessels. In this paper, we contrast 15 different geometrical and mechanical metrics of biaxial ascending aortic mechanics across 7 different types of possible control mice...
December 22, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28005131/strain-dependent-glucose-partitioning-in-meniscus-fibrocartilage
#3
Kelsey L Kleinhans, Alicia Jackson
A nearly avascular tissue, the knee meniscus relies on diffusive transport for nutritional supply to cells. Nutrient transport depends on solute partitioning in the tissue, which governs the amount of nutrients that can enter a tissue. The purpose of the present study was to investigate the effects of mechanical strain, tissue region, and tissue composition on the partition coefficient of glucose in meniscus fibrocartilage. A simple partitioning experiment was employed to measure glucose partitioning in porcine meniscus tissues from two regions (horn and central), from both meniscal components (medial and lateral), and at three levels of compression (0%, 10%, and 20%)...
December 22, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27996077/hybrid-rigid-deformable-model-for-prediction-of-neighboring-intervertebral-disc-loads-during-flexion-movement-after-lumbar-interbody-fusion-at-l3-4-level
#4
Tien Tuan Dao
Knowledge of spinal loads in neighboring discs after interbody fusion plays an important role in the clinical decision of this treatment as well as in the elucidation of its effect. However, controversial findings are still noted in the literature. Moreover, there are no existing models for efficient prediction of intervertebral disc stresses within annulus fibrosus (AF) and nucleus pulposus (NP) regions. In this present study, a new hybrid rigid-deformable modeling workflow was established to quantify the mechanical stress behavior within AF and NP regions of the L4-5, L2-3, and L1-2 discs after interbody fusion at L3-4 level...
December 20, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27935009/intracranial-pressure-influences-the-behavior-of-optic-nerve-head
#5
Yi Hua, Junfei Tong, Deepta Ghate, Sachin Kedar, Linxia Gu
In this work, the biomechanical responses of the optic nerve head (ONH) to acute elevations in intracranial pressure (ICP) were systematically investigated through numerical modeling. An orthogonal experimental design was developed to quantify the significance levels of ten input factors that govern the anatomy and material properties of the ONH model on the peak maximum principal strain (MPS) in the laminar cribrosa (LC) and post-laminar neural tissue (PLNT). Results show that the sensitivity of ONH responses to various input factors was region-specific...
December 9, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27925635/fatigue-detection-using-phase-space-warping
#6
Abdullatif Alwasel, Marcus Yung, Eihab Abdel-Rahman, Richard P Wells, Carl T Haas
A novel application of Phase-Space Warping (PSW) method to detect fatigue in the musculoskeletal system is presented. Experimental kinematic, force, and physiological signals are used to produce a fatigue metric. The metric is produced using time-delay embedding and PSW methods. Results showed that by using force and kinematic signals, an overall estimate of the muscle group state can be achieved. Further, when using electromyography (EMG) signals the fatigue metric can be used as a tool to evaluate muscles activation and load sharing patterns for individual muscles...
December 7, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27925634/influence-of-implant-surface-texture-design-on-peri-acetabular-bone-ingrowth-a-mechanobiology-based-finite-element-analysis
#7
Kaushik Mukherjee, Sanjay Gupta
The fixation of uncemented acetabular components largely depends on the amount of bone ingrowth, which is influenced by the design of the implant surface texture. The objective of this numerical study is to evaluate the effect of these implant texture design factors on bone ingrowth around an acetabular component. The novelty of this study lies in comparative Finite Element analysis of 3D microscale models of the implant-bone interface, considering patient-specific mechanical environment, host bone material property and implant-bone relative displacement, in combination with sequential mechanoregulatory algorithm and design of experiment based statistical framework...
December 7, 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28005134/a-validation-study-of-the-repeatability-and-accuracy-of-atomic-force-microscopy-indentation-using-polyacrylamide-gels-and-colloidal-probes
#8
Donghee Lee, Sangjin Ryu
The elasticity of soft biological materials is a critical property to understand their biomechanical behaviors. Atomic force microscopy (AFM) indentation method has been widely employed to measure the Young's modulus (E) of such materials. Although the accuracy of the method has been recently evaluated based on comparisons with macroscale E measurements, the repeatability of the method has yet to be validated for rigorous biomechanical studies of soft elastic materials. We tested the AFM indentation method using colloidal probes and polyacrylamide (PAAM) gels of E < 20 kPa as a model soft elastic material after having identified optimal trigger force and probe speed...
April 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27987299/an-improved-tibial-force-sensor-to-compute-contact-forces-and-contact-locations-in-vitro-after-total-knee-arthroplasty
#9
Joshua D Roth, Stephen M Howell, Maury L Hull
Contact force imbalance and contact kinematics (i.e., motion of the contact location in each compartment during flexion) of the tibiofemoral joint are both important predictors of a patient's outcome following total knee arthroplasty (TKA). Previous tibial force sensors have limitations in that they either did not determine contact forces and contact locations independently in the medial and lateral compartments or only did so within restricted areas of the tibial insert, which prevented them from thoroughly evaluating contact force imbalance and contact kinematics in vitro...
April 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28024161/the-effect-of-trabeculae-carneae-on-left-ventricular-diastolic-compliance-improvement-in-compliance-with-trabecular-cutting
#10
David L Halaney, Arnav Sanyal, Navid A Nafissi, Daniel Escobedo, Martin Goros, Joel Michalek, Pedro J Acevedo, William Pérez, G Patricia Escobar, Marc D Feldman, Hai-Chao Han
The role of trabeculae carneae in modulating left ventricular (LV) diastolic compliance remains unclear. The objective of this study was to determine the contribution of trabeculae carneae to the LV diastolic compliance. LV pressure-volume compliance curves were measured in six human heart explants from patients with LV hypertrophy at baseline and following trabecular cutting. The effect of trabecular cutting was also analyzed with finite-element model (FEM) simulations. Our results demonstrated that LV compliance improved after trabecular cutting (p < 0...
March 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27996078/physically-realizable-three-dimensional-bone-prosthesis-design-with-interpolated-microstructures
#11
Andrew D Cramer, Vivien J Challis, Anthony P Roberts
We present a new approach to designing three-dimensional, physically realizable porous femoral implants with spatially varying microstructures and effective material properties. We optimize over a simplified design domain to reduce shear stress at the bone-prosthetic interface with a constraint on the bone resorption measured using strain energy. This combination of objective and constraint aims to reduce implant failure and allows a detailed study of the implant designs obtained with a range of microstructure sets and parameters...
March 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27987301/evaluating-the-effects-of-ankle-foot-orthosis-mechanical-property-assumptions-on-gait-simulation-muscle-force-results
#12
Amy K Hegarty, Anthony J Petrella, Max J Kurz, Anne K Silverman
Musculoskeletal modeling and simulation techniques have been used to gain insights into movement disabilities for many populations, such as ambulatory children with cerebral palsy (CP). The individuals who can benefit from these techniques are often limited to those who can walk without assistive devices, due to challenges in accurately modeling these devices. Specifically, many children with CP require the use of ankle-foot orthoses (AFOs) to improve their walking ability, and modeling these devices is important to understand their role in walking mechanics...
March 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/27925636/on-the-two-dimensional-simplification-of-three-dimensional-cementless-hip-stem-numerical-models
#13
Fernando J Quevedo González, Michael Reimeringer, Natalia Nuño
Three-dimensional (3D) finite element (FE) models are commonly used to analyze the mechanical behavior of the bone under different conditions (i.e., before and after arthroplasty). They can provide detailed information but they are numerically expensive and this limits their use in cases where large or numerous simulations are required. On the other hand, 2D models show less computational cost, but the precision of results depends on the approach used for the simplification. Two main questions arise: Are the 3D results adequately represented by a 2D section of the model? Which approach should be used to build a 2D model that provides reliable results compared to the 3D model? In this paper, we first evaluate if the stem symmetry plane used for generating the 2D models of bone-implant systems adequately represents the results of the full 3D model for stair climbing activity...
March 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28114515/2016-editors-choice-papers
#14
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28056155/thank-you-to-all-2016-jbme-reviewers
#15
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28056154/annual-special-issue-biomechanical-engineering-year-in-review
#16
Beth Winkelstein, Victor Barocas
No abstract text is available yet for this article.
February 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28056147/2016-richard-skalak-award
#17
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28056131/journal-of-biomechanical-engineering-legacy-paper-2016
#18
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28056127/use-of-robotic-manipulators-to-study-diarthrodial-joint-function
#19
Richard E Debski, Satoshi Yamakawa, Volker Musahl, Hiromichi Fujie
Diarthrodial joint function is mediated by a complex interaction between bones, ligaments, capsules, articular cartilage, and muscles. To gain a better understanding of injury mechanisms and to improve surgical procedures, an improved understanding of the structure and function of diarthrodial joints needs to be obtained. Thus, robotic testing systems have been developed to measure the resulting kinematics of diarthrodial joints as well as the in situ forces in ligaments and their replacement grafts in response to external loading conditions...
February 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28056126/society-awards-2016
#20
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2017: Journal of Biomechanical Engineering
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