journal
MENU ▼
Read by QxMD icon Read
search

Journal of Biomechanical Engineering

journal
https://www.readbyqxmd.com/read/28334406/male-and-female-cervical-spine-biomechanics-and-anatomy-implication-for-scaling-injury-criteria
#1
Narayan Yoganandan, Cameron R Bass, Liming Voo, Frank A Pintar
There is an increased need to develop female-specific injury criteria and anthropomorphic test devices (dummies) for automotive and military environments, especially as women take occupational roles traditionally reserved for men. Although some exhaustive reviews on the biomechanics and injuries of the human spine have appeared in clinical and bioengineering literatures, focus on the difference between male and female cervical spine responses and characteristics has largely been ignored. Current neck injury criteria for automotive dummies for assessing crashworthiness and occupant safety are obtained from animal and human cadaver experiments, computational modeling and human volunteer studies...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28334372/simulations-imaging-and-modeling-a-unique-theme-for-an-undergraduate-research-program-in-biomechanics
#2
Stephanie M George, Zachary J Domire
As the reliance on computational models to inform experiments and evaluate medical devices grows, the demand for students with modeling experience will grow. In this paper, we report on the three year experience of a National Science Foundation funded Research Experiences for Undergraduates (REU) based on the theme simulations, imaging, and modeling in biomechanics. While directly applicable to REU sites, our findings also apply to those creating other types of summer undergraduate research programs. The objective of the paper is to examine if a theme of simulations, imaging, and modeling will improve students' understanding of the important topic of modeling, provide an overall positive research experience, and provide an interdisciplinary experience...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28334369/isotropic-failure-criteria-are-not-appropriate-for-anisotropic-fibrous-biological-tissues
#3
Christopher E Korenczuk, Lauren E Votava, Rohit Y Dhume, Shannen B Kizilski, George E Brown, Rahul Narain, Victor H Barocas
The von Mises (VM) stress is a common stress measure for finite-element models of tissue mechanics. The VM failure criterion, however, is inherently isotropic, and therefore may yield incorrect results for anisotropic tissues, and the relevance of the VM stress to anisotropic materials is not clear. We explored the application of a well-studied anisotropic failure criterion, the Tsai-Hill (TH) theory, to the mechanically anisotropic porcine aorta. Uniaxial dogbones were cut at different angles and stretched to failure...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28334367/modeling-of-stiffness-and-strength-of-bone-at-nanoscale
#4
Diab W Abueidda, Fereshteh A Sabet, Iwona M Jasiuk
Two distinct geometrical models of bone at nanoscale (collagen fibril and mineral platelets) are analyzed computationally. In the first model (Model I) minerals are periodically distributed in a staggered manner in a collagen matrix while in the second model (Model II) minerals form continuous layers outside the collagen fibril. Elastic modulus and strength of bone at the nanoscale, represented by these two models, are studied using a finite element software Abaqus. The analysis employs a traction-separation law (cohesive surface modeling) at various interfaces in the models to account for interfacial delaminations...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28334358/ranges-of-cervical-intervertebral-disc-deformation-during-an-in-vivo-dynamic-flexion-extension-of-the-neck
#5
Yan Yu, Haiqing Mao, Jing-Sheng Li, Tsung-Yuan Tsai, Liming Cheng, Kirkham B Wood, Guoan Li, Thomas D Cha
While abnormal loading is widely believed to cause cervical spine disc diseases, in-vivo cervical disc deformation during dynamic neck motion has not been well delineated. This study investigated the range of cervical disc deformation during an in-vivo functional flexion-extension of the neck. Ten asymptomatic human subjects were tested using a combined dual fluoroscopic imaging system and MRI based 3D modeling technique. Overall disc deformation was determined using the changes of the space geometry between upper and lower endplates of each intervertebral segment (C3/4, C4/5, C5/6 and C6/7)...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28334320/interbody-spacer-material-properties-and-design-conformity-for-reducing-subsidence-during-lumbar-interbody-fusion
#6
Lillian S Chatham, Vikas V Patel, Christopher M Yakacki, R Dana Carpenter
One major complication with lumbar spinal fusion surgery is subsidence, in which the interbody spacer penetrates the vertebral endplates. Towards reducing the risk of subsidence, the objective of this study was to investigate the effects of interbody spacer material and design on the stress in the lumbar spine after interbody fusion. A finite element model of the L4-L5 motion segment was developed from computed tomography images of a cadaveric lumbar spine. A spacer, pedicle screws, and posterior rods were incorporated into the model, and the system was loaded under axial compression...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28303276/a-parameterized-ultrasound-based-finite-element-analysis-of-the-mechanical-environment-of-pregnancy
#7
Andrea R Westervelt, Michael Fernandez, Michael House, Joy Vink, Chia-Ling Nhan-Chang, Ronald Wapner, Kristin M Myers
Preterm birth is the leading cause of childhood mortality, and can lead to health risks in survivors. The mechanical function of the uterus, fetal membranes, and cervix have dynamic roles to protect the fetus during gestation. To understand their mechanical function and relation to preterm birth, we built a 3-dimensional parameterized finite element model of pregnancy. This model is generated by an automated procedure that is informed by maternal ultrasound measurements. A baseline model at 25 weeks of gestation was characterized, and to visualize the impact of cervical structural parameters on tissue stretch we evaluated the model sensitivity to: (1) anterior uterocervical angle, (2) cervical length, (3) posterior cervical offset, and (4) cervical stiffness...
March 17, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28303275/modeling-pathological-hemodynamic-responses-to-the-valsalva-maneuver
#8
Leszek Pstras, Karl Thomaseth, Jacek Waniewski, Italo Balzani, Federico Bellavere
The Valsalva maneuver consisting in a forced expiration against closed airways is one of the most popular clinical tests of the autonomic nervous system function. When properly performed by a healthy subject, it features four characteristic phases of arterial blood pressure and heart rate variations, based on the magnitude of which the autonomic function may be assessed qualitatively and quantitatively. In patients with some disorders or in healthy patients subject to specific conditions, the pattern of blood pressure and heart rate changes during the execution of the Valsalva maneuver may, however, differ from the typical sinusoidal-like pattern...
March 17, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28303272/structural-and-functional-differences-between-aorta-and-vena-cava
#9
Jeffrey M Mattson, Yanhang Zhang
Elastin and collagen fibers are the major load-bearing extracellular matrix (ECM) constituents of the vascular wall. Arteries function differently than veins in the circulatory system, however as a result from several treatment options veins are subjected to sudden elevated arterial pressure. It is thus important to recognize the fundamental structure and function differences between a vein and an artery. Our research compared the relationship between biaxial mechanical function and ECM structure of porcine thoracic aorta and inferior vena cava...
March 17, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28303271/a-computational-method-for-analyzing-the-biomechanics-of-heart-murmurs
#10
Chi Zhu, Jung-Hee Seo, Hani Bakhshaee, Rajat Mittal
A computational framework consisting of a one-way coupled hemodynamic-acoustic method and a wave-decomposition based post-processing approach is developed to investigate the biomechanics of arterial bruits. This framework is then applied to studying the effect of the shear wave on the generation and propagation of bruits from a modeled stenosed artery. The blood flow in the artery is solved by an immersed boundary method (IBM) based incompressible flow solver. The sound generation and propagation in the blood volume is modeled by the linearized perturbed compressible equations, while the sound propagation through the surrounding tissue is modeled by the linear elastic wave equation...
March 17, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28291867/development-and-validation-of-a-brain-phantom-for-therapeutic-cooling-devices
#11
Ryan D M Packett, Philip Brown, Gautam S S Popli, F Scott Gayzik
Tissue cooling is a viable therapy for multiple conditions and injuries, and has been applied to the brain to treat epilepsy and concussions, leading to improved long-term outcomes. To facilitate the study of temperature reduction as a function of various cooling methods, a thermal brain phantom was developed and analyzed. The phantom is composed of a potassium-neutralized, superabsorbent co-polymer hydrogel. The phantom was tested in a series of cooling trials using a cooling block and 37 deg. water representing non-directional blood flow ranging up to 6 GPH, a physiologically representative range based on the prototype volume...
March 14, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28267191/characterization-and-correction-of-errors-in-computing-contact-location-between-curved-articular-surfaces-application-to-total-knee-arthroplasty
#12
Joshua D Roth, Stephen M Howell, Maury L Hull
Previous reports of tibial force sensors have neither characterized nor corrected errors in the computed contact location between the femoral and tibial components in total knee arthroplasty (TKA) that are theoretically caused by the curved articular surface of the tibial component. The objectives were to experimentally characterize there errors and to develop and validate an error correction algorithm. The errors were characterized by calculating the difference between the errors in the computed contact location when forces were applied normal to the tibial articular surface and those when forces were applied normal to the tibial baseplate...
March 7, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28241270/collagen-organization-in-facet-capsular-ligaments-varies-with-spinal-region-and-with-ligament-deformation
#13
Ehsan Ban, Sijia Zhang, Vahhab Zarei, Victor H Barocas, Beth A Winkelstein, Catalin R Picu
The spinal facet capsular ligament (FCL) is primarily comprised of heterogeneous arrangements of collagen fibers. This complex fibrous structure and its evolution under loading play a critical role in determining the mechanical behavior of the FCL. A lack of analytical tools to characterize the spatial anisotropy and heterogeneity of the FCL's microstructure has limited the current understanding of its structure-function relationships. Here, the collagen organization was characterized using spatial correlation analysis of its optically-obtain fiber orientation field...
February 21, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28303274/design-of-a-wireless-medical-capsule-for-measuring-the-contact-pressure-between-a-capsule-and-the-small-intestine
#14
Pengbo Li, Craig Kreikemeier-Bower, Wanchuan Xie, Vishal Kothari, Benjamin S Terry
A wireless medical capsule for measuring the contact pressure between a mobile capsule and the small intestine lumen was developed. Two pressure sensors were used to measure and differentiate the contact pressure and the small intestine intraluminal pressure. After in vitro tests of the capsule, it was surgically placed and tested in the proximal small intestine of a pig model. The capsule successfully gathered and transmitted the pressure data to a receiver outside the body. The measured pressure signals in the animal test were analyzed in the time and frequency domains, and a mathematic model was presented to describe the different factors influencing the contact pressure...
May 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28267190/changes-in-joint-contact-mechanics-in-a-large-quadrupedal-animal-model-after-partial-meniscectomy-and-a-focal-cartilage-injury
#15
David J Heckelsmiller, M James Rudert, Thomas E Baer, Douglas R Pedersen, Douglas C Fredericks, Jessica E Goetz
Acute mechanical damage and the resulting joint contact abnormalities are central to the initiation and progression of post-traumatic osteoarthritis (PTOA). Study of PTOA is typically performed in vivo with replicate animals using artificially induced injury features. The goal of this work was to measure changes in a joint contact stress in the knee of a large quadruped after creation of a clinically realistic overload injury and a focal cartilage defect. Whole-joint overload was achieved by excising a 5-mm wedge of the anterior medial meniscus...
May 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28267189/association-of-placental-jets-and-mega-jets-with-reduced-villous-density
#16
Rojan Saghian, Joanna L James, Merryn H Tawhai, Sally L Collins, Alys R Clark
Spiral arteries (SAs) lie at the interface between the uterus and placenta, and supply nutrients to the placental surface. Maternal blood circulation is separated from the fetal circulation by structures called villous trees. SAs are transformed in early pregnancy from tightly coiled vessels to large high-capacity channels, which is believed to facilitate an increased maternal blood flow throughout pregnancy with minimal increase in velocity, preventing damage to delicate villous trees. Significant maternal blood flow velocities have been theorized in the space surrounding the villi (the intervillous space, IVS), particularly when SA conversion is inadequate, but have only recently been visualized reliably using pulsed wave Doppler ultrasonography...
May 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28267188/the-relationship-of-three-dimensional-human-skull-motion-to-brain-tissue-deformation-in-magnetic-resonance-elastography-studies
#17
Andrew A Badachhape, Ruth J Okamoto, Ramona S Durham, Brent D Efron, Sam J Nadell, Curtis L Johnson, Philip V Bayly
In traumatic brain injury (TBI), membranes such as the dura mater, arachnoid mater, and pia mater play a vital role in transmitting motion from the skull to brain tissue. Magnetic resonance elastography (MRE) is an imaging technique developed for noninvasive estimation of soft tissue material parameters. In MRE, dynamic deformation of brain tissue is induced by skull vibrations during magnetic resonance imaging (MRI); however, skull motion and its mode of transmission to the brain remain largely uncharacterized...
May 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28249082/are-non-newtonian-effects-important-in-hemodynamic-simulations-of-patients-with-autogenous-fistula
#18
S M Javid Mahmoudzadeh Akherat, Kevin Cassel, Michael Boghosian, Promila Dhar, Mary Hammes
Given the current emphasis on accurate computational fluid dynamics (CFD) modeling of cardiovascular flows, which incorporates realistic blood vessel geometries and cardiac waveforms, it is necessary to revisit the conventional wisdom regarding the influences of non-Newtonian effects. In this study, patient-specific reconstructed 3D geometries, whole blood viscosity data, and venous pulses postdialysis access surgery are used as the basis for the hemodynamic simulations of renal failure patients with native fistula access...
April 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28241206/remote-determination-of-time-dependent-stiffness-of-surface-degrading-polymer-scaffolds-via-synchrotron-based-imaging
#19
N K Bawolin, X B Chen
Surface-degrading polymers have been widely used to fabricate scaffolds with the mechanical properties appropriate for tissue regeneration/repair. During their surface degradation, the material properties of polymers remain approximately unchanged, but the scaffold geometry and thus mechanical properties vary with time. This paper presents a novel method to determine the time-dependent mechanical properties, particularly stiffness, of scaffolds from the geometric changes captured by synchrotron-based imaging, with the help of finite element analysis (FEA)...
April 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28241201/automated-quantification-of-the-impact-of-defects-on-the-mechanical-behavior-of-deoxyribonucleic-acid-origami-nanoplates
#20
Bowen Liang, Anand Nagarajan, Michael W Hudoba, Ricardo Alvarez, Carlos E Castro, Soheil Soghrati
Deoxyribonucleic acid (DNA) origami is a method for the bottom-up self-assembly of complex nanostructures for applications, such as biosensing, drug delivery, nanopore technologies, and nanomechanical devices. Effective design of such nanostructures requires a good understanding of their mechanical behavior. While a number of studies have focused on the mechanical properties of DNA origami structures, considering defects arising from molecular self-assembly is largely unexplored. In this paper, we present an automated computational framework to analyze the impact of such defects on the structural integrity of a model DNA origami nanoplate...
April 1, 2017: Journal of Biomechanical Engineering
journal
journal
27769
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"