Lama Mohammad Saffouh Al-Hanbali, Ahmad Sharafeddin Burhan, Mohammad Younis Hajeer, Kinda Sultan, Fehmieh Rafik Nawaya
BACKGROUND: Pain is an unpleasant experience and annoying sensation. To control this pain during orthodontic separation, different pharmacological and non-pharmacological methods have been used. OBJECTIVE: This systematic review and meta-analysis aimed to critically assess the evidence of the effectiveness of pharmacological and non-pharmacological methods in reducing pain induced by orthodontic separation. SEARCH STRATEGY: An electronic search was conducted using the following databases: PubMed® (Medline), Scopus®, EMBASE®, Web of ScienceTM, Google ScholarTM, ProQuest, and Cochrane Central Register of controlled trials (CENTRAL) searching for the studies published between January 2012 and April 2023...
January 1, 2024: European Journal of Orthodontics