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Journal of Infection

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https://www.readbyqxmd.com/read/28077283/aetiology-of-febrile-pharyngitis-in-children-potential-of-myxovirus-resistance-protein-a-mxa-as-a-biomarker-of-viral-infection
#1
Lauri Ivaska, Jussi Niemelä, Johanna Lempainen, Riikka Österback, Matti Waris, Tytti Vuorinen, Jukka Hytönen, Kaisu Rantakokko-Jalava, Ville Peltola
OBJECTIVES: Besides group A streptococcus (GAS), microbial causes of pharyngitis in children are not well known. We aimed to document the viral and bacterial aetiology of pharyngitis and to assess the pathogenic role of viruses by determining the myxovirus resistance protein A (MxA) in the blood as a marker of interferon response. METHODS: In this prospective observational study, throat swabs and blood samples were collected from children (age 1-16 years) presenting to the emergency department with febrile pharyngitis...
January 7, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28077282/the-changing-face-of-bacteraemia-in-an-hiv-1-positive-cohort-in-the-united-kingdom
#2
LETTER
Aliya N Bryce, Jordan P Skittrall, Yvonne Gilleece, Catherine Sargent
No abstract text is available yet for this article.
January 7, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28065808/bacterial-meningitis-in-alcoholic-patients-a-population-based-prospective-study
#3
Kiril E B van Veen, Matthijs C Brouwer, Arie van der Ende, Diederik van de Beek
OBJECTIVES: To study clinical features and outcome of community-acquired bacterial meningitis in alcoholic patients. METHODS: Patients with a history of alcoholism were selected from our nationwide, prospective cohort on community-acquired bacterial meningitis performed from March 2006 to October 2014. Data on patient history, symptoms and signs on admission, treatment, and outcome were prospectively collected. RESULTS: Of 1359 included episodes, 88 episodes (6%) occurred in 88 alcoholic patients...
January 5, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28065807/comparison-of-in%C3%A2-vitro-synergy-of-various-%C3%AE-lactams-with-vancomycin-against-methicillin-resistant-staphylococcus-aureus
#4
LETTER
Chun-Hsing Liao, Shey-Ying Chen, Yu-Tsung Huang, Hsih-Yen Tsai, Po-Ren Hsueh
No abstract text is available yet for this article.
January 5, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28043826/vancomycin-therapy-in-secondary-care-investigating-factors-that-impact-therapeutic-target-attainment
#5
LETTER
Timothy M Rawson, Esmita Charani, Luke S P Moore, Pau Herrero, Ji Soo Baik, Akash Philip, Mark Gilchrist, Eimear T Brannigan, Pantelis Georgiou, William Hope, Alison H Holmes
No abstract text is available yet for this article.
December 30, 2016: Journal of Infection
https://www.readbyqxmd.com/read/28043825/measles-a-tale-of-two-sisters-vaccine-failure-and-the-resurgence-of-an-old-foe
#6
LETTER
Aleem Ahmed, Amandip Sahota, Iain Stephenson, Kevin E Brown, Julian W Tang
No abstract text is available yet for this article.
December 30, 2016: Journal of Infection
https://www.readbyqxmd.com/read/28025161/association-of-weekend-effect-with-early-mortality-in-severe-sepsis-patients-over-time
#7
Yu-Ning Shih, Yung-Tai Chen, Chia-Jen Shih, Shuo-Ming Ou, Yen-Tao Hsu, Ran-Chou Chen, Imoigele P Aisiku, Raghu R Seethala, Gyorgy Frendl, Peter C Hou
BACKGROUND: The aim of this study is to investigate the "weekend effect" and early mortality of patients with severe sepsis. METHODS: Using the Taiwanese National Healthcare Insurance Research Database, all patients who were hospitalized for the first time with an episode of severe sepsis between January 2000 and December 2011 were identified and the short-term mortality of patients admitted on weekdays was compared to those admitted on weekends. The primary endpoint was 7-day mortality...
December 23, 2016: Journal of Infection
https://www.readbyqxmd.com/read/28017824/detection-of-fusarium-specific-t-cells-in-hematologic-patients-with-invasive-fusariosis
#8
LETTER
Daniela Vallerini, Fabio Forghieri, Ivana Lagreca, Giovanni Riva, Patrizia Barozzi, Chiara Quadrelli, Monica Morselli, Paola Bresciani, Angela Cuoghi, Valeria Coluccio, Monica Maccaferri, Ambra Paolini, Elisabetta Colaci, Roberto Marasca, Franco Narni, Monica Cellini, Anne Beauvais, Jean-Paul Latgè, Luigina Romani, Lorenzo Iughetti, Patrizia Comoli, Daniele Campioli, Tommaso Trenti, Mario Luppi, Leonardo Potenza
No abstract text is available yet for this article.
December 23, 2016: Journal of Infection
https://www.readbyqxmd.com/read/28017826/determining-vancomycin-etest-mics-in-patients-with-mrsa-bloodstream-infection-does-not-support-switching-antimicrobials
#9
Nina J Hos, Nathalie Jazmati, Danuta Stefanik, Martin Hellmich, Halil AlSael, Winfried V Kern, Siegbert Rieg, Hilmar Wisplinghoff, Harald Seifert, Achim J Kaasch
OBJECTIVES: Elevated vancomycin minimum inhibitory concentrations (MIC) have been reported to adversely affect clinical outcome in methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI). We therefore examined the association between vancomycin MIC and outcome considering various potential confounders. METHODS: Clinical data and bacterial isolates were prospectively collected from patients with MRSA BSI from 2006 to 2012 as part of the Invasive Staphylococcus aureus Infection Cohort (INSTINCT) study...
December 22, 2016: Journal of Infection
https://www.readbyqxmd.com/read/28017825/diagnosis-of-pulmonary-tuberculosis-and-assessment-of-treatment-response-through-analyses-of-volatile-compound-patterns-in-exhaled-breath-samples
#10
Nicola M Zetola, Chawangwa Modongo, Ogopotse Matsiri, Tsaone Tamuhla, Bontle Mbongwe, Keikantse Matlhagela, Enoch Sepako, Alexandro Catini, Giorgio Sirugo, Eugenio Martinelli, Roberto Paolesse, Corrado Di Natale
OBJECTIVES: We determined the performance of a sensor array (an electronic nose) made of 8 metalloporphyrins coated quartz microbalances sensors for the diagnosis and prognosis of pulmonary tuberculosis (TB) using exhaled breath samples. METHODS: TB cases and healthy controls were prospectively enrolled. Signals from volatile organic compounds (VOCs) in breath samples were measured at days 0, 2, 7, 14, and 30 of TB therapy and correlated with clinical and microbiological measurements...
December 22, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27998752/drug-resistant-tb-uk-multicentre-study-drums-treatment-management-and-outcomes-in-london-and-west-midlands-2008-2014
#11
Amber Arnold, Graham S Cooke, Onn Min Kon, Martin Dedicoat, Marc Lipman, Angela Loyse, Philip D Butcher, Irina Chis Ster, Thomas Stephen Harrison
OBJECTIVES: Detailed information regarding treatment practices and outcomes of MDR-TB treatment in the UK is required as a baseline for care improvements. METHODS: 100 consecutive cases between 2008 and 2014 were reviewed retrospectively at 4 MDR-TB treatment centres in England to obtain information on drug treatment choices, hospital admission duration and outcomes for MDR-TB. RESULTS: Initial hospital admission was long, median 62.5 (IQR 20-106, n = 92) days, and 13% (12/92) of patients lost their home during this period...
December 18, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27998751/laboratory-features-of-160-cchf-confirmed-cases-in-zabol-of-iran-a-10-year-study
#12
LETTER
Hamid Owaysee Osquee, Hadi Pourjafar, Sepehr Taghizadeh, Mehdi Haghdoost, Fereshteh Ansari
No abstract text is available yet for this article.
December 18, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27998750/clinical-translation-of-polymyxin-based-combination-therapy-facts-challenges-and-future-opportunities
#13
REVIEW
Xueli Zhang, Fengmei Guo, Hua Shao, Xiao Zheng
The emergence and spread of multidrug resistant Gram-negative bacteria has led to a resurgence in the clinical use of polymyxin antibiotics. However, the prevalence of polymyxin resistance is on the rise at an alarming rate, motivating the idea of combination therapy to sustain the revival of these "old" antibiotics. Although ample evidence in favor of combination therapy has emerged, it seems impracticable and confusing to find a promising combination from the diverse reports or gain adequate information on the efficacy and safety profile...
December 18, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27998749/the-history-of-plasma-viral-load-and-cd4-count-impacts-the-size-of-hiv-1-reservoir
#14
LETTER
E K Alidjinou, O Robineau, A Chéret, F Ajana, E Drumez, M Kyheng, P Choisy, D Hober, L Bocket
No abstract text is available yet for this article.
December 18, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27998748/hev-infection-in-french-hiv-infected-patients
#15
Florence Abravanel, Sébastien Lhomme, Mélanie Fougère, Karine Saune, Muriel Alvarez, Jean-Marie Péron, Pierre Delobel, Jacques Izopet
OBJECTIVES: The reported prevalence of anti-hepatitis E virus antibodies in HIV-positive patients from industrialized countries varies greatly. It is also difficult to compare these data with the anti-IgG prevalence in the general population because age and sex are not matched in most studies. Moreover, MSM are at increased risk of viral hepatitis. METHODS: HEV is endemic in southwestern France. We investigated therefore 300 HIV-infected patients consecutively attending the out-patient clinic of Toulouse University Hospital...
December 18, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27940176/clinical-presentation-and-outcome-of-twenty-cases-of-invasive-meningococcal-disease-due-to-serogroup-c-clonal-complex-11-in-the-florence-province-italy-2015-2016
#16
LETTER
Francesco Maria Fusco, Filippo Baragli, Barbara Del Pin, Rosario Spina, Italo Calamai, Patrizia Pecile, Eleonora Riccobono, Francesco Nieddu, Maria Moriondo, Alessandro Miglietta, Fabio Voller, Cecilia Fazio, Paola Stefanelli, Massimo Di Pietro
No abstract text is available yet for this article.
December 8, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27939814/visualizing-viable-mycobacterium-tuberculosis-in-sputum-to-monitor-isolation-measures
#17
LETTER
Benjamin Wyplosz, Faiza Mougari, May Al Rawi, Céline Baillon, Dhiba Marigot-Outtandy, Damien Le Dû, Mathilde Jachym, Vincent Hervé, Laurent Raskine, Emmanuelle Cambau
No abstract text is available yet for this article.
December 7, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27919645/empirical-mono-versus-combination-antibiotic-therapy-in-adult-intensive-care-patients-with-severe-sepsis-a-systematic-review-with-meta-analysis-and-trial-sequential-analysis
#18
REVIEW
Fredrik Sjövall, Anders Perner, Morten Hylander Møller
OBJECTIVES: To assess benefits and harms of empirical mono- vs. combination antibiotic therapy in adult patients with severe sepsis in the intensive care unit (ICU). METHODS: We performed a systematic review according to the Cochrane Collaboration methodology, including meta-analysis, risk of bias assessment and trial sequential analysis (TSA). We included randomised clinical trials (RCT) assessing empirical mono-antibiotic therapy versus a combination of two or more antibiotics in adult ICU patients with severe sepsis...
December 3, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27914992/whole-genome-sequencing-and-comparative-genomic-analysis-of-bordetella-pertussis-isolates-from-the-2007-2008-epidemic-in-israel
#19
LETTER
Sophie Octavia, Sunny Z Wu, Sandeep Kaur, Lea Valinsky, Esther Marva, Jacob Moran-Gilad, Ruiting Lan
No abstract text is available yet for this article.
November 30, 2016: Journal of Infection
https://www.readbyqxmd.com/read/27889413/molecular-diagnosis-of-bloodstream-infections-in-onco-haematology-patients-with-pcr-esi-ms-technology
#20
Elena Jordana-Lluch, Belén Rivaya, Clara Marcó, Montserrat Giménez, Mª Dolores Quesada, Agustín Escobedo, Montserrat Batlle, Elisa Martró, Vicente Ausina
OBJECTIVES: Onco-haematological patients are prone to develop infections, and antibiotic prophylaxis may lead to negative blood cultures. Thus, the microbiological diagnosis and subsequent administration of a targeted antimicrobial therapy is often difficult. The goal of this study was to evaluate the usefulness of IRIDICA (PCR/ESI-MS technology) for the molecular diagnosis of bloodstream infections in this patient group. METHODS: A total of 463 whole blood specimens from different sepsis episodes in 429 patients were analysed using the PCR/ESI-MS platform, comparing the results with those of blood culture and other clinically relevant information...
November 23, 2016: Journal of Infection
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