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Journal of Infection

Irene Muñoz-Gallego, Giancarlo Candela Ganoza, Fernando Chaves, Rafael San Juan, M Angeles Orellana
No abstract text is available yet for this article.
May 17, 2017: Journal of Infection
Jung-Yien Chien, Rodrigo E Mendes, Lalitagauri M Deshpande, Po-Ren Hsueh
No abstract text is available yet for this article.
May 12, 2017: Journal of Infection
Bin Xiang, Wenxian Zhu, Renrong You, Libin Chen, Yaling Li, Jianpeng Liang, Qiuyan Lin, Ming Liao, Chencheng Xiao, Tao Ren
No abstract text is available yet for this article.
May 11, 2017: Journal of Infection
Syed Beenish Rufai, Amit Singh, Jitendra Singh, Parveen Kumar, Manimuthu Mani Sankar, Sarman Singh
OBJECTIVE: Tuberculous meningitis (TBM) is the most severe form of extra-pulmonary tuberculosis (TB) due to association of diseases with high rates of mortality and morbidity. Diagnosis continues to be a clinical challenge as microbiological confirmation is rare and time consuming resulting in delayed treatment. Xpert MTB/RIF assay is a rapid and simple test, which has been endorsed by World Health Organization as an initial diagnostic test for the diagnosis of TBM. However, evidence still lacks for its performance on cerebrospinal fluid (CSF) for the diagnosis of TBM especially from India...
May 10, 2017: Journal of Infection
Thomas Harder, Judith Koch, Ole Wichmann, Wiebke Hellenbrand
IMPORTANCE: Human serum bactericidal antibody levels (hSBA) are commonly used as an immune correlate of protection after vaccination against meningococcal disease. We performed a systematic review of how well this marker correlates with protection induced by outer membrane vesicle (OMV) vaccines against meningococcal B (MenB) disease. OBJECTIVE: To compare vaccine effectiveness (VE) of OMV vaccines against MenB predicted by hSBA (predicted protection) to VE from clinical studies (observed protection)...
May 6, 2017: Journal of Infection
Guifeng Yang, Zhihua Liu, Juncheng Yang, Kangxian Luo, Ying Xu, Haitang He, Qunfang Fu, Shouyi Yu, Zhanhui Wang
OBJECTIVES: To identify within-host quasispecies characteristics of hepatitis B virus (HBV) in mothers and children infected via mother-to-child transmission (MTCT). METHODS: Using next-generation sequencing (NGS), we analyzed sequences within the non-overlapping pre-core/core (pre-C/C) gene in 37 mother-child pairs. RESULTS: Phylogenetic and Highlighter analyses suggested that both a single strain and multiple distinct strains may be transmitted in MTCT of HBV...
May 5, 2017: Journal of Infection
Vanessa Clifford, Marc Tebruegge, Christel Zufferey, Susie Germano, Ben Forbes, Lucy Cosentino, Emma McBryde, Damon Eisen, Roy Robins-Browne, Alan Street, Justin Denholm, Nigel Curtis
OBJECTIVES: A biomarker indicating successful tuberculosis (TB) therapy would assist in determining appropriate length of treatment. This study aimed to determine changes in mycobacteria-specific antigen-induced cytokine biomarkers in patients receiving therapy for latent or active TB, to identify biomarkers potentially correlating with treatment success. METHODS: A total of 33 adults with active TB and 36 with latent TB were followed longitudinally over therapy...
May 5, 2017: Journal of Infection
Mohamed Jeljeli, Valérie Guérin-El Khourouj, Myriam Hormi, Ghislaine Sterkers, Virginie Pommelet, Pierre Gressens, Albert Faye
No abstract text is available yet for this article.
May 3, 2017: Journal of Infection
Rafael Mahieu, Viviane Cassisa, Delphine Hilliquin, Noémie Coron, Hélène Pailhoriès, Marie Kempf, Marie-Laure Joly-Guillou, Matthieu Eveillard
No abstract text is available yet for this article.
April 29, 2017: Journal of Infection
Ray Borrow, Dominique A Caugant, Mehmet Ceyhan, Hannah Christensen, Ener Cagri Dinleyici, Jamie Findlow, Linda Glennie, Anne Von Gottberg, Amel Kechrid, Julio Vázquez Moreno, Aziza Razki, Vincent Smith, Muhamed-Kheir Taha, Hassiba Tali-Maamar, Khalid Zerouali
The Global Meningococcal Initiative (GMI) has recently considered current issues in Middle Eastern and African countries, and produced two recommendations: (i) that vaccination of attendees should be considered for some types of mass-gathering events, as some countries mandate for the Hajj, and (ii) vaccination of people with human immunodeficiency virus should be used routinely, because of increased meningococcal disease (MD) risk. Differences exist between Middle Eastern and African countries regarding case and syndrome definitions, surveillance, and epidemiologic data gaps...
April 25, 2017: Journal of Infection
Ines Carloni, Silvia Ricci, Chiara Azzari, Silvia Galletti, Giacomo Faldella, Fernando Maria de Benedictis
No abstract text is available yet for this article.
April 21, 2017: Journal of Infection
Laura Behar, David Chadwick, Angela Dunne, Christopher I Jones, Claire Proctor, Chakravarthi Rajkumar, Paula Sharratt, Philip Stanley, Angela Whiley, Mark Wilks, Martin J Llewelyn
OBJECTIVES: To establish risk factors for Clostridium difficile colonization among hospitalized patients in England. METHODS: Patients admitted to elderly medicine wards at three acute hospitals in England were recruited to a prospective observational study. Participants were asked to provide a stool sample as soon as possible after enrolment and then weekly during their hospital stay. Samples were cultured for C. difficile before ribotyping and toxin detection by PCR...
April 21, 2017: Journal of Infection
Merel M Koopmans, Merijn W Bijlsma, Matthijs C Brouwer, Diederik van de Beek, Arie van der Ende
OBJECTIVES: Listeria monocytogenes can cause sepsis and meningitis. We report national surveillance data on L. monocytogenes meningitis in the Netherlands, describing incidence changes, genetic epidemiology and fatality rate. METHODS: We analyzed data from the Netherlands Reference Laboratory of Bacterial Meningitis for cases of L.monocytogenes meningitis. Strains were assessed by serotyping and bacterial population structure by multi-locus sequence typing. RESULTS: A total of 375 cases of Listeria meningitis were identified between 1985 and 2014...
April 15, 2017: Journal of Infection
Qingfu Xu, Jareth Wischmeyer, Eduardo Gonzalez, Michael E Pichichero
OBJECTIVES: We sought to understand how polymicrobial colonization varies during health, viral upper respiratory infection (URI) and acute upper respiratory bacterial infection to understand differences in infection-prone vs. non-prone patients. METHODS: Nasopharyngeal (NP) samples were collected from 74 acute otitis media (AOM) infection-prone and 754 non-prone children during 2094 healthy visits, 673 viral URI visits and 631 AOM visits. Three otopathogens Streptococcus pneumoniae (Spn), Nontypeable Haemophilus influenzae (NTHi), and Moraxella catarrhalis (Mcat) were identified by culture...
April 13, 2017: Journal of Infection
Yaling Li, Wenbao Qi, Jun Qiao, Chuangfu Chen, Ming Liao, Chencheng Xiao
No abstract text is available yet for this article.
April 6, 2017: Journal of Infection
Fuchun Zhang, Yuhai Bi, Jian Wang, Gary Wong, Weifeng Shi, Fengyu Hu, Yang Yang, Liuqing Yang, Xilong Deng, Songfeng Jiang, Xi He, Yingxia Liu, Chibiao Yin, Nanshan Zhong, George F Gao
No abstract text is available yet for this article.
April 6, 2017: Journal of Infection
Ali Pormohammad, Seyed-Mohammad Riahi, Mohammad Javad Nasiri, Fatemeh Fallah, Mohammad Aghazadeh, Farahnoosh Doustdar, Ramin Pouriran
INTRODUCTION: The measurement of adenosine deaminase (ADA) level in cerebrospinal fluid (CSF) has generated as a suitable test for tuberculous meningitis (TBM) diagnosis. The main objective in the present meta-analysis focused on analyzing the ADA test accuracy in order to diagnose TBM. METHODS: We searched several databases including Medline, Embase and Cochrane databases to identify studies addressing the diagnosis of TBM. The quality of included reports were assessed by RevMan5 software (via QUADS2 checklist)...
March 31, 2017: Journal of Infection
Olivier Baldesi, Sébastien Bailly, Stéphane Ruckly, Alain Lepape, François L'Heriteau, Martine Aupee, Sandrine Boussat, Caroline Bervas, Anais Machut, Anne Berger-Carbonne, Anne Savey, Jean François Timsit
OBJECTIVE: Candidaemia is a life-threatening infectious disease, associated with septic shock, multiple organ failure, and a high mortality rate. In France, reported data on the incidence of ICU-acquired candidaemia and the causative Candida species are scarce. The objective of this study was to determine temporal trends in epidemiology and risk factors of intensive care unit-acquired candidaemia (ICU-Cand) and ICU mortality among a very large population of ICU patients. METHOD: Demographics, patient risk factors, invasive device exposure and nosocomial infection in ICU patient were collected from 2004 to 2013 in a national network of 213 ICUs: REA-RAISIN...
March 31, 2017: Journal of Infection
Dennis F Simonsen, Dóra K Farkas, Charles R Horsburgh, Reimar W Thomsen, Henrik T Sørensen
BACKGROUND: Cancer may increase risk of active tuberculosis but evidence is sparse. We therefore examined tuberculosis risk in patients with incident cancer using Danish nationwide medical databases. METHODS: We conducted a matched follow-up study comparing risk of active tuberculosis in cancer-exposed individuals to that in a general population comparison cohort, matched on gender, age, and country of origin, in different follow-up intervals using Cox regression...
March 31, 2017: Journal of Infection
Staci L Sudenga, Alan G Nyitray, B Nelson Torres, Roberto Silva, Luisa Villa, Eduardo Lazcano-Ponce, Martha Abrahamsen, Maria Luiza Baggio, Jorge Salmeron, Manuel Quiterio, Anna R Giuliano
OBJECTIVES: Globally, anal cancer incidence is rare, but is increasing in some world regions. Our objective was to assess differences in anal HPV natural history in three countries. METHODS: Men aged 18-70 years were recruited from the US (n = 634), Mexico (n = 665), and Brazil (n = 731). Anal specimens were collected every six-months. HPV genotyping was assessed by Linear Array. Anal HPV prevalence was compared using the Fisher's exact test. HPV infection incidence rates (IR) and 95% confidence intervals (CI) were calculated...
March 28, 2017: Journal of Infection
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