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Journal of Infection

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https://www.readbyqxmd.com/read/28189714/the-impact-of-co-infection-of-influenza-a-virus-on-the-on-severity-of-middle-east-respiratory-syndrome-coronavirus
#1
LETTER
Sarah H Alfaraj, Jaffar A Al-Tawfiq, Nojoom A Alzahrani, Talal Altwaijri, Ziad A Memish
No abstract text is available yet for this article.
February 9, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28189713/the-painting-of-st-roch-in-the-picture-gallery-of-bari-15-th-century-an-ancient-representation-of-dracunculiasis
#2
LETTER
Raffaele Gaeta, Fabrizio Bruschi, Valentina Giuffra
No abstract text is available yet for this article.
February 9, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28189712/interleukin-1-receptor-antagonist-a-biomarker-of-response-to-anti-tb-treatment-in-hiv-tb-co-infected-patients
#3
Janin Nouhin, Polidy Pean, Yoann Madec, Mathieu F Chevalier, Celine Didier, Laurence Borand, François-Xavier Blanc, Daniel Scott-Algara, Didier Laureillard, Laurence Weiss
OBJECTIVES: Despite the high frequency of tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) in human immunodeficiency virus (HIV)/TB co-infected patients, no diagnostic test is available. Here, we investigated whether monocyte/macrophage activation markers can predict TB-IRIS occurrence and if they are modulated by anti-TB treatment. METHODS: Frozen plasma was obtained from 127 HIV/TB co-infected adults naïve for antiretroviral therapy, enrolled in the CAMELIA trial, 36 of whom developed TB-IRIS...
February 9, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28189711/model-informed-risk-assessment-for-zika-virus-outbreaks-in-the-asia-pacific-regions
#4
Yue Teng, Dehua Bi, Guigang Xie, Yuan Jin, Yong Huang, Baihan Lin, Xiaoping An, Yigang Tong, Dan Feng
Recently, Zika virus (ZIKV) has been recognized as a significant threat to global public health. The disease was present in large parts of the Americas, the Caribbean, and also the western Pacific area with southern Asia during 2015 and 2016. However, little is known about the factors affecting the transmission of ZIKV. We used Gradient Boosted Regression Tree models to investigate the effects of various potential explanatory variables on the spread of ZIKV, and used current with historical information from a range of sources to assess the risks of future ZIKV outbreaks...
February 9, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28188817/a-sensitive-and-specific-rapid-diagnostic-test-for-severe-fever-with-thrombocytopenia-syndrome-virus
#5
LETTER
Xiao-Ai Zhang, Sabrina Li, Jesus Ching, Zhen-Dong Yang, Ning Cui, Pan-He Zhang, Jian-Gong Hu, Wei Liu
No abstract text is available yet for this article.
February 7, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28167123/low-incidence-of-acute-hepatitis-c-virus-infection-among-southern-spanish-hiv-infected-individuals
#6
LETTER
María Mancebo, Juan Macías, Nicolás Merchante, Luis M Real, Fernando Lozano, Lara Domínguez, María J Álvarez-Ossorio, Fernando Saussol, Pilar Rincón, Juan A Pineda, Karin Neukam
No abstract text is available yet for this article.
February 3, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28143756/real-world-persistence-with-antiretroviral-therapy-for-hiv-in-the-united-kingdom-a-multicentre-retrospective-cohort-study
#7
Joseph M Lewis, Colette Smith, Adele Torkington, Craig Davies, Shazaad Ahmad, Andrew Tomkins, Jonathan Shaw, Margaret Kingston, Ghadeer Muqbill, Philip Hay, Larissa Mulka, Deborah Williams, Laura Waters, Nataliya Brima, Neal Marshall, Margaret Johnson, Mas Chaponda, Mark Nelson
OBJECTIVES: Persistence with an antiretroviral therapy (ART) regimen for HIV can be defined as the length of time a patient remains on therapy before stopping or switching. We aimed to describe ART persistence in treatment naïve patients starting therapy in the United Kingdom, and to describe differential persistence by treatment regimen. METHODS: We performed a retrospective cohort study at eight UK centres of ART-naïve adults commencing ART between 2012 and 2015...
January 29, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28143755/rabies-transmission-following-organ-transplantation-in-china
#8
LETTER
Cheng Gong, Xiaomei Li, Ming Luo, Zhen Zhang, Qinghai Wang, Qing Wang, Lu Zhang, Fang Huang, Tiegang Zhang, Tao Zhou, Fan Yang, Qing Tang, Fan Jiang, Li Lu, Jiang Wu
No abstract text is available yet for this article.
January 29, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28143754/brucella-endocarditis-clinical-features-and-treatment-outcomes-of-10-cases-from-xinjiang-china
#9
LETTER
Bin Jia, Fengbo Zhang, Pan Pang, Tao Zhang, Rongjiong Zheng, Wenbao Zhang, Yuexin Zhang, Jianbing Ding
No abstract text is available yet for this article.
January 28, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28130143/treatment-limiting-renal-tubulopathy-in-patients-treated-with-tenofovir-disoproxil-fumarate
#10
L Hamzah, S Jose, J W Booth, A Hegazi, M Rayment, A Bailey, D I Williams, B M Hendry, P Hay, R Jones, J B Levy, D R Chadwick, M Johnson, C A Sabin, F A Post
OBJECTIVES: Tenofovir disoproxil fumarate (TDF) is widely used in the treatment or prevention of HIV and hepatitis B infection. TDF may cause renal tubulopathy in a small proportion of recipients. We aimed to study the risk factors for developing severe renal tubulopathy. METHODS: We conducted an observational cohort study with retrospective identification of cases of treatment-limiting tubulopathy during TDF exposure. We used multivariate Poisson regression analysis to identify risk factors for tubulopathy, and mixed effects models to analyse adjusted estimated glomerular filtration rate (eGFR) slopes...
January 25, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28130144/blood-culture-pcr-to-optimise-typhoid-fever-diagnosis-after-controlled-human-infection-identifies-frequent-asymptomatic-cases-and-evidence-of-primary-bacteraemia
#11
Thomas C Darton, Liqing Zhou, Christoph J Blohmke, Claire Jones, Claire S Waddington, Stephen Baker, Andrew J Pollard
BACKGROUND: Improved diagnostics for typhoid are needed; a typhoid controlled human infection model may accelerate their development and translation. Here, we evaluated a blood culture-PCR assay for detecting infection after controlled human infection with S. Typhi and compared test performance with optimally performed blood cultures. METHODOLOGY/PRINCIPAL FINDINGS: Culture-PCR amplification of blood samples was performed alongside daily blood culture in 41 participants undergoing typhoid challenge...
January 24, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28130142/antibiotic-therapy-prior-to-hospital-admission-is-associated-with-reduced-septic-shock-and-need-for-mechanical-ventilation-in-patients-with-community-acquired-pneumonia
#12
Rosanel Amaro, Jacobo Sellarés, Eva Polverino, Catia Cillóniz, Miquel Ferrer, Laia Fernández-Barat, Josep Mensa, Michael S Niederman, Antoni Torres
A subgroup of patients admitted to the hospital with a diagnosis of community-acquired pneumonia (CAP) have received antibiotic therapy prior to admission for the current episode of pneumonia. The objective of this study was to assess the clinical course of patients receiving antibiotics prior to admission, compared to patients not previously treated. An observational cohort of 3364 CAP patients consecutively admitted to our hospital, and prospectively included, were studied. We collected clinical, microbiological and biochemical parameters, focusing on recent antibiotics received prior to admission...
January 24, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28126493/pneumocystis-jiroveci-pneumonia-and-gata2-deficiency-expanding-the-spectrum-of-the-disease
#13
LETTER
María Fernanda González-Lara, Andrea Wisniowski-Yáñez, Santiago Pérez-Patrigeon, Amy P Hsu, Steven M Holland, Jennifer M Cuellar-Rodríguez
No abstract text is available yet for this article.
January 23, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28126492/no-evidence-for-cross-protection-of-the-hpv-16-18-vaccine-against-hpv-6-11-positivity-in-female-sti-clinic-visitors
#14
Petra J Woestenberg, Audrey J King, Marianne A B van der Sande, Robine Donken, Suzan Leussink, Fiona R M van der Klis, Christian J P A Hoebe, Johannes A Bogaards, Birgit H B van Benthem
OBJECTIVES: Data from a vaccine trial and from post-vaccine surveillance in the United Kingdom have suggested that the bivalent HPV-16/18 vaccine offers cross-protection against HPV-6/11 and protection against anogenital warts (AGW). We studied the effect of the bivalent vaccine on genital HPV-6/11 positivity and AGW in the Netherlands. METHODS: We included all vaccine-eligible women from the PASSYON study, a biennial cross-sectional study among 16- to 24-year-old sexually transmitted infection (STI) clinic attendants...
January 23, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28109676/importation-of-zika-virus-in-china-a-significant-risk-in-southern-china
#15
LETTER
Bin Xiang, Pei Gao, Yinfeng Kang, Tao Ren
No abstract text is available yet for this article.
January 18, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28109675/human-infection-with-an-avian-influenza-a-h9n2-virus-in-guangdong-in-2016
#16
LETTER
Runyu Yuan, Lijun Liang, Jie Wu, Yinfeng Kang, Yingchao Song, Lirong Zou, Xin Zhang, Hanzhong Ni, Changwen Ke
No abstract text is available yet for this article.
January 18, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28104387/impact-of-echinocandin-on-prognosis-of-proven-invasive-candidiasis-in-icu-a-post-hoc-causal-inference-model-using-the-amarcand2-study
#17
Sébastien Bailly, Olivier Leroy, Elie Azoulay, Philippe Montravers, Jean-Michel Constantin, Hervé Dupont, Didier Guillemot, Olivier Lortholary, Jean-Paul Mira, Pierre-François Perrigault, Jean-Pierre Gangneux, Jean-François Timsit
OBJECTIVE: guidelines recommend first-line systemic antifungal treatment (SAT) with echinocandins in invasive candidiasis (IC), especially in critically ill patients. This study aimed at assessing the impact of echinocandins compared to azoles as initial SAT on the 28-day prognosis in adult ICU patients. METHODS: From the prospective multicenter AmarCAND2 cohort (835 patients), we selected those with documented IC and treated with echinocandins (ECH) or azoles (AZO)...
January 16, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28104386/haemagglutinin-and-neuraminidase-sequencing-delineate-nosocomial-influenza-outbreaks-with-accuracy-equivalent-to-whole-genome-sequencing
#18
Rebecca Houghton, Joanna Ellis, Monica Galiano, Tristan W Clark, Sarah Wyllie
OBJECTIVES: We describe haemagglutinin (HA) and neuraminidase (NA) sequencing in an apparent cross-site influenza A(H1N1) outbreak in renal transplant and haemodialysis patients, confirmed with whole genome sequencing (WGS). METHODS: Isolates were sequenced from influenza positive individuals. Phylogenetic trees were constructed using HA and NA sequencing and subsequently WGS. Sequence data was analysed to determine genetic relatedness of viruses obtained from inpatient and outpatient cohorts and compared with epidemiological outbreak information...
January 16, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28077283/aetiology-of-febrile-pharyngitis-in-children-potential-of-myxovirus-resistance-protein-a-mxa-as-a-biomarker-of-viral-infection
#19
Lauri Ivaska, Jussi Niemelä, Johanna Lempainen, Riikka Österback, Matti Waris, Tytti Vuorinen, Jukka Hytönen, Kaisu Rantakokko-Jalava, Ville Peltola
OBJECTIVES: Besides group A streptococcus (GAS), microbial causes of pharyngitis in children are not well known. We aimed to document the viral and bacterial aetiology of pharyngitis and to assess the pathogenic role of viruses by determining the myxovirus resistance protein A (MxA) in the blood as a marker of interferon response. METHODS: In this prospective observational study, throat swabs and blood samples were collected from children (age 1-16 years) presenting to the emergency department with febrile pharyngitis...
January 7, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28077282/the-changing-face-of-bacteraemia-in-an-hiv-1-positive-cohort-in-the-united-kingdom
#20
LETTER
Aliya N Bryce, Jordan P Skittrall, Yvonne Gilleece, Catherine Sargent
No abstract text is available yet for this article.
January 7, 2017: Journal of Infection
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