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Journal of Infection

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https://www.readbyqxmd.com/read/30408494/unusual-neisseria-species-as-a-cause-of-infection-in-patients-taking-eculizumab
#1
Page E Crew, Lucy McNamara, Peter E Waldron, Lynda McCulley, S Christopher Jones, Susan J Bersoff-Matcha
BACKGROUND: Non-meningococcal, non-gonococcal Neisseria spp. are typically commensal and rarely cause invasive disease. Eculizumab is a terminal complement inhibitor that increases susceptibility to meningococcal disease, but data on disease caused by typically-commensal Neisseria spp. are lacking. This series describes postmarketing reports of typically-commensal Neisseria spp. disease in patients receiving eculizumab. METHODS: We searched the FDA Adverse Event Reporting System (FAERS) and medical literature for reports of commensal Neisseria spp...
November 5, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30408493/impact-of-a-poorly-performing-point-of-care-test-during-the-2017-2018-influenza-season
#2
LETTER
Julian W Tang, Janice Blount, Carina Bradley, Bernadette Donaghy, Carol Shardlow, Srini Bandi, Caroline Baxter, Ann Hunter, Simon Range, Tommy Ty Lam
No abstract text is available yet for this article.
November 5, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30391632/bronchoalveolar-lavage-aspergillus-galactomannan-lateral-flow-assay-versus-aspergillus-specific-lateral-flow-device-test-for-diagnosis-of-invasive-pulmonary-aspergillosis-in-patients-with-hematological-malignancies
#3
LETTER
Jeffrey D Jenks, Sanjay R Mehta, Randy Taplitz, Nancy Law, Sharon L Reed, Martin Hoenigl
No abstract text is available yet for this article.
November 1, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30391631/two-novel-reassortant-high-pathogenic-h7n9-viruses-isolated-in-southern-china-in-fifth-wave-shows-internal-genomic-diversity-and-high-virulence-in-chickens-and-ducks
#4
LETTER
Lihong He, Dong Liu, Jiao Hu, Lei Shi, Jiao Liu, Tianyu Cai, Liwei Shi, Han Gu, Jiangyan Zhao, Xiaoquan Wang, Min Gu, Shunlin Hu, Xiaowen Liu, Zenglei Hu, Xiufan Liu
No abstract text is available yet for this article.
November 1, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30391630/genomes-of-escherichia-coli-bacteraemia-isolates-originating-from-urinary-tract-foci-contain-more-virulence-associated-genes-than-those-from-non-urinary-foci-and-neutropaenic-hosts
#5
Dr Adam P Dale, Dr Anish K Pandey, Dr Richard J Hesp, Dr Konstantinos Belogiannis, Dr Jay R Laver, Dr Clifford C Shone, Professor Robert C Read
OBJECTIVES: Escherichia coli is the leading cause of bacteraemia. In an era of emerging multi-drug-resistant strains, development of effective preventative strategies will be informed by knowledge of strain diversity associated with specific infective syndromes/patient groups. We hypothesised that the number of virulence factor (VF) genes amongst bacteraemia isolates from neutropaenic patients would be lower than isolates from immunocompetent patients. METHODS: Immunocompetent and neutropaenic adults with E...
November 1, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30391548/the-burden-of-serious-fungal-disease-in-the-uk-infections-with-rare-organisms
#6
LETTER
Andrew M Borman, Adrien Szekely, Michael D Palmer, Mark Fraser, Zoe Patterson, Elizabeth M Johnson
No abstract text is available yet for this article.
October 31, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30389423/first-report-of-a-novel-hiv-1-recombinant-form-crf100_01c-comprising-crf01_ae-and-c-among-heterosexuals-in-yunnan-china
#7
LETTER
Yue Feng, Chunyue Zhang, Mi Zhang, Li Gao, Jing Miao, Yuanyuan Jia, Xingqi Dong, Xueshan Xia
No abstract text is available yet for this article.
October 30, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30367886/rapid-evolving-h7n9-avian-influenza-a-viruses-pose-new-challenge
#8
LETTER
Zhiqing Pu, Tingting Luo, Jinjin Yang, Xuejuan Shen, David M Irwin, Ming Liao, Yongyi Shen
No abstract text is available yet for this article.
October 24, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30367885/tolerance-of-mrsa-st239-tw-to-chlorhexidine-based-decolonization-evidence-for-keratinocyte-invasion-as-a-mechanism-of-biocide-evasion
#9
Helene Marbach, Gema Vizcay-Barrena, Kaveh Memarzadeh, Jonathan A Otter, Smriti Pathak, Robert P Allaker, Richard D Harvey, Jonathan D Edgeworth
OBJECTIVES: Information on genetic determinants of chlorhexidine tolerance (qacA carriage and MIC) in vitro is available, although evidence of the clinical impact and mechanisms remain poorly understood. We investigated why, following chlorhexidine intervention, prevalent epidemic MRSA ST22 and ST36 clones declined at an ICU, whilst an ST239-TW clone did not. The chlorhexidine tolerant ST239-TW phenotypes were assessed for their protein binding, cell adhesion and intracellular uptake potential...
October 24, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30339803/risk-factors-of-multidrug-resistant-tuberculosis-a-global-systematic-review-and-meta-analysis
#10
REVIEW
Ivan Surya Pradipta, Lina Davies Forsman, Judith Bruchfeld, Eelko Hak, Jan-Willem Alffenaar
OBJECTIVES: Since the risk of multidrug-resistant tuberculosis (MDR-TB) may depend on the setting, we aimed to determine the associations of risk factors of MDR-TB across different regions. METHODS: A systematic review and meta-analysis was performed with Pubmed and Embase databases. Information was retrieved on 37 pre-defined risk factors of MDR-TB. We estimated overall Mantel-Haenszel odds ratio as a measure of the association. RESULTS: Factors of previous TB disease and treatment are the most important risk factors associated with MDR-TB...
October 16, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30336176/gut-dysbiosis-and-paediatric-crohn-s-disease
#11
REVIEW
Andrea Brusaferro, Elena Cavalli, Edoardo Farinelli, Rita Cozzali, Nicola Principi, Susanna Esposito
OBJECTIVES: The main objective of this manuscript is to discuss our present knowledge of the relationships between dysbiosis and paediatric Crohn's disease (CD). The therapeutic role of the methods currently used to re-establish normal gut microbiota composition is also analysed. METHODS: PubMed was used to search for all of the studies published from January 2008 to June 2018 using the key words: "Crohn's disease" and "gut dysbiosis" or "microbiota" or "microbioma" or "probiotic" and "children" or "paediatric"...
October 15, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30312647/risk-factors-for-mortality-among-carbapenem-resistant-enterobacteriaceae-carriers-with-focus-on-immunosuppression
#12
Haggai Bar-Yoseph, Nadav Cohen, Alexander Korytny, Elias R Andrawus, Razi Even Dar, Yuval Geffen, Khetam Hussein, Mical Paul
OBJECTIVES: To identify risk factors for mortality in a cohort of carbapenem-resistant enterobacteriaceae (CRE) carriers, focusing on immunosuppression and other risk factors known at the time of CRE carriage detection. METHODS: We prospectively followed all new and known CRE carriers admitted between June 2016 and June 2017 to a single tertiary center in Israel. Patients were included in the study after confirmation of the carrier state. Demographic and clinical data were documented on admission or CRE acquisition and patients were followed prospectively post-discharge until January 2018 or death...
October 10, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30312646/identification-of-musculoskeletal-infection-with-non-tuberculous-mycobacterium-using-metagenomic-sequencing
#13
LETTER
Zida Huang, Chongjing Zhang, Xinyu Fang, Wenbo Li, Chaofan Zhang, Wenming Zhang, Bin Yang
No abstract text is available yet for this article.
October 10, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30308215/microbiological-and-clinical-characteristics-of-acinetobacter-baumannii-bacteremia-implications-of-sequence-type-for-prognosis
#14
Yu-Chung Chuang, Aristine Cheng, Hsin-Yun Sun, Jann-Tay Wang, Yee-Chun Chen, Wang-Huei Sheng, Shan-Chwen Chang
OBJECTIVES: Acinetobacter baumannii (Ab) is an important cause of healthcare-associated infections. Multilocus sequence typing (MLST) provides a highly discriminative typing method. We aimed to determine the clinical impact of Ab sequence types (ST) in patients with bloodstream infection (BSI). METHODS: Patients with Ab-BSI were followed prospectively from 2009 to 2014. We randomly selected one-third of non-duplicate bacteremic isolates for MLST and correlated the Ab ST with the clinical course...
October 8, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30292782/missed-hepatitis-b-birth-dose-vaccine-is-a-risk-factor-for-incomplete-vaccination-at-18-and-24-months
#15
Peyton Wilson, Genevieve Taylor, Jamie Knowles, Elizabeth Blyth, Jeff Laux, Jacob Lohr, Ravi Jhaveri
OBJECTIVES: To determine whether missing the HepB birth dose vaccine is a risk factor for incomplete vaccination later in childhood. METHODS: This was a retrospective cohort study of infants born over one year at an academic medical center. The "not vaccinated at birth" group consisted of all infants who did not receive the HepB birth dose vaccine by seven days of life, while the "vaccinated at birth" group included infants who did receive the birth dose...
October 4, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30273623/pcr-cycle-threshold-to-assess-a-diagnostic-stewardship-intervention-for-c-difficile-testing
#16
LETTER
Gregory R Madden, Melinda D Poulter, Costi D Sifri
No abstract text is available yet for this article.
September 28, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30268515/epidemiologic-estimates-of-hepatitis-e-virus-infection-in-european-countries
#17
Johannes Horn, Mahrrouz Hoodgarzadeh, Carolina J Klett-Tammen, Rafael T Mikolajczyk, Gérard Krause, Jördis J Ott
OBJECTIVES: Reliable epidemiologic estimates of Hepatitis E Virus (HEV) infection and evidence on factors determining country-differences are sparse. We systematically assessed and extracted research data on three HEV infection markers and identified factors influencing HEV-positivity to generated adjusted EU/EEA country-specific estimates by a meta-analysis. METHODS: Reports on HEV published 2005-2015 for EU/EEA countries were obtained from PubMed, Embase, Scopus, and Cochrane databases...
September 27, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30267802/herpes-simplex-virus-hsv-pneumonia-in-the-non-ventilated-immunocompromised-host-burden-and-predictors
#18
Luzzati Roberto, D'Agaro Pierlanfranco, Busca Annalisa, Maurel Cristina, Martellani Fulvia, Rosin Chiara, Segat Ludovica, Gatti Giuseppe, Mascarello Marta, Confalonieri Marco
OBJECTIVES: To evaluate burden and predictors of HSV pneumonia among immunocompromised patients not undergoing invasive mechanical ventilation according to a tailored diagnostic algorithm. METHODS: This prospective, observational study included immunocompromised adults with pneumonia non-responding to empirical antibiotic therapy. Bronchoalveolar lavage (BAL) specimens were cultured for bacteria, mycobacteria and fungi. Real-time PCR for Herpesviruses and other microorganisms were performed on BAL and other specimens...
September 26, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30267801/triacetylfusarinine-c-a-urine-biomarker-for-diagnosis-of-invasive-aspergillosis
#19
Martin Hoenigl, Thomas Orasch, Klaus Faserl, Juergen Prattes, Juergen Loeffler, Jan Springer, Fabio Gsaller, Frederike Reischies, Wiebke Duettmann, Reinhard B Raggam, Herbert Lindner, Hubertus Haas
OBJECTIVES: Early diagnosis of invasive aspergillosis (IA) remains challenging, with available diagnostics being limited by inadequate sensitivities and specificities. Triacetylfusarinine C, a fungal siderophore that has been shown to accumulate in urine in animal models, is a potential new biomarker for diagnosis of IA. METHODS: We developed a method allowing absolute and matrix-independent mass spectrometric quantification of TAFC. Urine TAFC, normalized to creatinine, was determined in 44 samples from 24 patients with underlying hematologic malignancies and probable, possible or no IA according to current EORTC/MSG criteria and compared to other established biomarkers measured in urine and same-day blood samples...
September 26, 2018: Journal of Infection
https://www.readbyqxmd.com/read/30267800/social-patterning-of-telephone-health-advice-for-diarrhoea-and-vomiting-analysis-of-24-million-telehealth-calls-in-england
#20
Natalie L Adams, Tanith C Rose, Alex J Elliot, Gillian Smith, Roger Morbey, Paul Loveridge, James Lewis, Gareth Studdard, Mara Violato, Sarah J O'Brien, Margaret Whitehead, David C Taylor-Robinson, Jeremy I Hawker, Benjamin Barr
OBJECTIVES: Gastrointestinal (GI) infections are common and most people do not see a physician. There is conflicting evidence of the impact of socioeconomic status (SES) on risk of GI infections. We assessed the relationship between SES and GI calls to two National Health Service (NHS) telephone advice services in England. METHODS: Over 24 million calls to NHS Direct (2010-13) and NHS 111 (2013-15) were extracted from Public Health England (PHE) syndromic surveillance systems...
September 26, 2018: Journal of Infection
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