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Journal of Infection

Ines Carloni, Silvia Ricci, Silvia Galletti, Chiara Azzari, Giacomo Faldella, Fernando Maria de Benedictis
No abstract text is available yet for this article.
April 21, 2017: Journal of Infection
Laura Behar, David Chadwick, Angela Dunne, Christopher I Jones, Clare Procter, Chakravathi Rajkumar, Paula Sharratt, Philip Stanley, Angela Whiley, Mark Wilks, Martin J Llewelyn
OBJECTIVES: To establish risk factors for Clostridium difficile colonization among hospitalized patients in England. METHODS: Patients admitted to elderly medicine wards at three acute hospitals in England were recruited to a prospective observational study. Participants were asked to provide a stool sample as soon as possible after enrolment and then weekly during their hospital stay. Samples were cultured for C. difficile before ribotyping and toxin detection by PCR...
April 20, 2017: Journal of Infection
Merel M Koopmans, Merijn W Bijlsma, Matthijs C Brouwer, Diederik van de Beek, Arie van der Ende
OBJECTIVES: Listeria monocytogenes can cause sepsis and meningitis. We report national surveillance data on L. monocytogenes meningitis in the Netherlands, describing incidence changes, genetic epidemiology and fatality rate. METHODS: We analyzed data from the Netherlands Reference Laboratory of Bacterial Meningitis for cases of L.monocytogenes meningitis. Strains were assessed by serotyping and bacterial population structure by multi-locus sequence typing. RESULTS: A total of 375 cases of Listeria meningitis were identified between 1985 and 2014...
April 15, 2017: Journal of Infection
Qingfu Xu, Jareth Wischmeyer, Eduardo Gonzalez, Michael E Pichichero
OBJECTIVES: We sought to understand how polymicrobial colonization varies during health, viral upper respiratory infection (URI) and acute upper respiratory bacterial infection to understand differences in infection-prone vs. non-prone patients. METHODS: Nasopharyngeal (NP) samples were collected from 74 acute otitis media (AOM) infection-prone and 754 non-prone children during 2094 healthy visits, 673 viral URI visits and 631 AOM visits. Three otopathogens Streptococcus pneumoniae (Spn), Nontypeable Haemophilus influenzae (NTHi), and Moraxella catarrhalis (Mcat) were identified by culture...
April 13, 2017: Journal of Infection
Yaling Li, Wenbao Qi, Jun Qiao, Chuangfu Chen, Ming Liao, Chencheng Xiao
No abstract text is available yet for this article.
April 6, 2017: Journal of Infection
Fuchun Zhang, Yuhai Bi, Jian Wang, Gary Wong, Weifeng Shi, Fengyu Hu, Yang Yang, Liuqing Yang, Xilong Deng, Songfeng Jiang, Xi He, Yingxia Liu, Chibiao Yin, Nanshan Zhong, George F Gao
No abstract text is available yet for this article.
April 6, 2017: Journal of Infection
Ali Pormohammad, Seyed-Mohammad Riahi, Mohammad Javad Nasiri, Fatemeh Fallah, Mohammad Aghazadeh, Farahnoosh Doustdar, Ramin Pouriran
INTRODUCTION: The measurement of adenosine deaminase (ADA) level in cerebrospinal fluid (CSF) has generated as a suitable test for tuberculous meningitis (TBM) diagnosis. The main objective in the present meta-analysis focused on analyzing the ADA test accuracy in order to diagnose TBM. METHODS: We searched several databases including Medline, Embase and Cochrane databases to identify studies addressing the diagnosis of TBM. The quality of included reports were assessed by RevMan5 software (via QUADS2 checklist)...
March 31, 2017: Journal of Infection
Olivier Baldesi, Sébastien Bailly, Stéphane Ruckly, Alain Lepape, François L'Heriteau, Martine Aupee, Sandrine Boussat, Caroline Bervas, Anais Machut, Anne Berger-Carbonne, Anne Savey, Jean François Timsit
OBJECTIVE: Candidaemia is a life-threatening infectious disease, associated with septic shock, multiple organ failure, and a high mortality rate. In France, reported data on the incidence of ICU-acquired candidaemia and the causative Candida species are scarce. The objective of this study was to determine temporal trends in epidemiology and risk factors of intensive care unit-acquired candidaemia (ICU-Cand) and ICU mortality among a very large population of ICU patients. METHOD: Demographics, patient risk factors, invasive device exposure and nosocomial infection in ICU patient were collected from 2004 to 2013 in a national network of 213 ICUs: REA-RAISIN...
March 31, 2017: Journal of Infection
Dennis F Simonsen, Dóra K Farkas, Charles R Horsburgh, Reimar W Thomsen, Henrik T Sørensen
BACKGROUND: Cancer may increase risk of active tuberculosis but evidence is sparse. We therefore examined tuberculosis risk in patients with incident cancer using Danish nationwide medical databases. METHODS: We conducted a matched follow-up study comparing risk of active tuberculosis in cancer-exposed individuals to that in a general population comparison cohort, matched on gender, age, and country of origin, in different follow-up intervals using Cox regression...
March 31, 2017: Journal of Infection
Staci L Sudenga, Alan G Nyitray, B Nelson Torres, Roberto Silva, Luisa Villa, Eduardo Lazcano-Ponce, Martha Abrahamsen, Maria Luiza Baggio, Jorge Salmeron, Manuel Quiterio, Anna R Giuliano
OBJECTIVES: Globally, anal cancer incidence is rare, but is increasing in some world regions. Our objective was to assess differences in anal HPV natural history in three countries. METHODS: Men aged 18-70 years were recruited from the US (n = 634), Mexico (n = 665), and Brazil (n = 731). Anal specimens were collected every six-months. HPV genotyping was assessed by Linear Array. Anal HPV prevalence was compared using the Fisher's exact test. HPV infection incidence rates (IR) and 95% confidence intervals (CI) were calculated...
March 28, 2017: Journal of Infection
Pelagia Reidy, Alie Wurie, Wayne Barnes, Emily Carr, David Kamau, Darrelle Marsden, Kerry Mundell, Lisa Watson, Megan Paveley, Buyiswa Lizzie Sithole, Tonny M Sekikongo, Andy M Johnston, Tom E Fletcher
No abstract text is available yet for this article.
March 24, 2017: Journal of Infection
M Pearson, J L Fallowfield, T Davey, N Thorpe, A Allsopp, A Shaw, D Wilson, S Sriskandan, L Lamb
AIMS: A prospective observational study was conducted in Royal Marines (RM) recruits to investigate throat carriage of group A Streptococcus (GAS) and incidence of soft tissue infections. METHODS: 1012 RM recruits were followed through a 32-week training programme, with throat swabs being obtained in weeks 1, 6, 15, and 32. Alongside a separate cohort of 46 RM Young Officers (YO) undergoing training were sampled in parallel. RESULTS: Carriage of group A Streptococcus was detected in only 5/1012 (0...
March 23, 2017: Journal of Infection
Wong Nicholas, Aleem Ahmed, Osama Ahmed, Fadwa Elsanousi, James Veater, Jane Osborne, Emma Aarons, Julian W Tang
No abstract text is available yet for this article.
March 23, 2017: Journal of Infection
Mamoona Chaudhry, Hamad B Rashid, Angélique Angot, Michael Thrusfield, Susan C Welburn, Barend M deC Bronsvoort, Ilaria Capua, Giovanni Cattoli, Mark C Eisler
No abstract text is available yet for this article.
March 23, 2017: Journal of Infection
Po Ying Chia, Haur Sen Yew, Hanley Ho, Angela Chow, Sapna P Sadarangani, Monica Chan, Yiu Wing Kam, Chia Yin Chong, Koh Cheng Thoon, Chee Fu Yung, Jia Hui Li, David C Lye, Partha Pratim De, Lisa F P Ng, Tsin Wen Yeo, Yee Sin Leo
No abstract text is available yet for this article.
March 23, 2017: Journal of Infection
Qianqian Qi, Qian Wang, Weizao Chen, Fei Yu, Lanying Du, Dimiter S Dimitrov, Lu Lu, Shibo Jiang
No abstract text is available yet for this article.
March 18, 2017: Journal of Infection
Insa Joost, Achim Kaasch, Christine Pausch, Gabriele Peyerl-Hoffmann, Christian Schneider, Reinhard E Voll, Harald Seifert, Winfried V Kern, Siegbert Rieg
OBJECTIVES: Patients with rheumatoid arthritis (RA) are considered to be at increased risk of severe infections. We here describe the clinical characteristics, course and outcome of RA patients with Staphylococcus aureus bacteremia (SAB). METHODS: We conducted a post hoc analysis of data from a German bi-center prospective SAB cohort study (period 2006-2014). Patients were followed-up for one year. Primary and secondary outcomes were survival time and osteoarticular infection (OAI)...
March 18, 2017: Journal of Infection
Ronald Anderson, Charles Feldman
Acute pulmonary and cardiac injury remain significant causes of morbidity and mortality in those afflicted with severe pneumococcal disease, with the risk for early mortality often persisting several years beyond clinical recovery. Although remaining to be firmly established in the clinical setting, a considerable body of evidence, mostly derived from murine models of experimental infection, has implicated the pneumococcal, cholesterol-binding, pore-forming toxin, pneumolysin (Ply), in the pathogenesis of lung and myocardial dysfunction...
March 16, 2017: Journal of Infection
Aina Gomila, Josep Ma Badia, Jordi Carratalà, Xavier Serra-Aracil, Evelyn Shaw, Vicens Diaz-Brito, Antoni Castro, Elena Espejo, Carmen Nicolás, Marta Piriz, Montserrat Brugués, Josefina Obradors, Ana Lérida, Jordi Cuquet, Enric Limón, Francesc Gudiol, Miquel Pujol
OBJECTIVE: To determine current outcomes and predictors of treatment failure among patients with surgical site infection (SSI) after colorectal surgery. METHODS: A multicentre observational prospective cohort study of adults undergoing elective colorectal surgery in 10 Spanish hospitals (2011-2014). Treatment failure was defined as persistence of signs/symptoms of SSI or death at 30 days post-surgery. RESULTS: Of 3,701 patients, 669 (18.1%) developed SSI; 336 (9...
March 15, 2017: Journal of Infection
I Parent du Chatelet, A E Deghmane, D Antona, E Hong, L Fonteneau, M K Taha, D Lévy-Bruhl
OBJECTIVES: This work aimed to describe the epidemiology of invasive meningococcal disease (IMD) in France, 2006-2015, including group- and genotype-specific disease burden, incidence trends before and after introduction of meningococcal C conjugate vaccines (MCCV) in 2010, and factors influencing the case fatality rate. METHODS: Mandatory notification data on incidence and IMD case characteristics were used. Genotyping of invasive strains and whole genome sequencing were performed by the French National Reference Center...
March 7, 2017: Journal of Infection
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