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Journal of Infection

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https://www.readbyqxmd.com/read/28648496/fruits-as-the-vehicle-of-drug-resistant-pathogenic-yeasts
#1
Hsiu-Jung Lo, Sheng-Hua Tsai, Wen-Li Chu, Yin-Zhi Chen, Zi-Li Zhou, Hong-Fu Chen, Ching-Fu Lee, Yun-Liang Yang
OBJECTIVE: We investigated the diversity and drug susceptibility of pathogenic yeasts on fruit surfaces. METHOD: Fruits were purchased from supermarkets and washed with buffer. The pellets were re-suspended in medium after centrifugation. The cell suspensions were plated onto CHROMagar Candida medium. Yeasts were identified by ribosomal DNA sequencing and their drug susceptibilities were determined by broth microdilution assay. RESULTS: Of 184 isolates, comprised of 55 species, from 22 different types of fruits, 29 species, including Candida famata, Candida fermentati, Candida guilliermondii, Candida intermedia, Candida krusei, Candida orthopsilosis, Candida parapsilosis, Candida pelliculosa, Candida tropicalis, and others have been reported to cause diseases in humans...
June 22, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28648495/comparison-of-zika-virus-zikv-rna-detection-in-plasma-whole-blood-and-urine-case-series-of-travel-associated-zikv-infection-imported-to-italy-2016
#2
Giada Rossini, Paolo Gaibani, Caterina Vocale, Roberto Cagarelli, Maria Paola Landini
OBJECTIVES: The capability to detect ZIKV RNA is of crucial importance for cases confirmation. However, due to the short-lived viremia, the detection of ZIKV RNA in plasma/serum is challenging for samples collected more than one week after onset of clinical illness. We compared the window time and detection rate of ZIKV RNA in different specimen types (plasma, whole blood and urine) collected simultaneously at several times post-symptom onset. METHODS: We examined the presence of ZIKV RNA in matched specimens of whole blood, plasma and urine collected in the same date (3-28 days after symptom onset) from 10 ZIKV infected patients...
June 22, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28633888/burden-of-acute-gastroenteritis-caused-by-norovirus-in-china-a-systematic-review
#3
Hong-Lu Zhou, Shan-Shan Zhen, Jin-Xia Wang, Can-Jing Zhang, Chao Qiu, Song-Mei Wang, Xi Jiang, Xuan-Yi Wang
BACKGROUND: To understand the epidemiology and disease burden of norovirus (NoVs) gastroenteritis in China, a systematic review was conducted. METHODS: Studies on acute gastroenteritis (AGE) caused by NoVs from mainland China, published before 2017 were searched. All retrieved articles were screened and reviewed by a standardized algorithm. NoVs detection rates as well as strain variations by ages, seasonal variations and geographic locations were analyzed using random-effects model...
June 17, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28599954/cmv-specific-t-cell-immunity-in-solid-organ-transplant-recipients-at-low-risk-of-cmv-infection-chronology-and-applicability-in-preemptive-therapy
#4
Juan Damián Mena-Romo, Pilar Pérez Romero, Cecilia Martín-Gandul, Miguel Ángel Gentil, Gonzalo Suárez-Artacho, Ernesto Lage, Magdalena Sánchez, Elisa Cordero
OBJECTIVES: To characterize whether the CMV-specific cellular immune response can be used as a predictor of the control of CMV infection and disease and determine thresholds in solid organ transplant (SOT) recipients seropositive for CMV (R+). METHODS: The CMV-specific T-cell response was characterized using intracellular cytokine staining and the evolution of clinical and virological parameters were recorded during the first year after transplantation. RESULTS: Besides having positive CMV serology, only 28...
June 11, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28606432/a-cohort-study-of-patients-suspected-for-mers-cov-in-a-referral-hospital-in-saudi-arabia
#5
LETTER
Jaffar A Al-Tawfiq, Sarah H Alfaraj, Talal A Altuwaijri, Ziad A Memish
No abstract text is available yet for this article.
June 9, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28602860/a-role-for-the-tetraspanin-proteins-in-salmonella-infection-of-human-macrophages
#6
Noha A Hassuna, Peter N Monk, Fawwaz Ali, Robert C Read, Lynda J Partridge
OBJECTIVE: Infected macrophages play a role in the dissemination of Salmonella and may serve as a reservoir of infection in asymptomatic carriers. However, relatively little is known about the early molecular interactions of the bacteria with these cells. We have recently shown that members of the tetraspanin family of membrane proteins are involved in the initial adhesion of a range of bacteria to host cells. This study investigated the role of tetraspanins in Salmonella enterica subsp...
June 8, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28601577/impact-of-faecal-microbiota-transplantation-to-eradicate-vancomycin-resistant-enterococci-vre-colonization-in-humans
#7
LETTER
Benjamin Davido, Rui Batista, H Fessi, Jérôme Salomon, Aurélien Dinh
No abstract text is available yet for this article.
June 7, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28587831/clinical-characteristics-and-risk-factors-for-mortality-in-adult-patients-with-persistent-candidemia
#8
Seung Ji Kang, Seong Eun Kim, Uh Jin Kim, Hee-Chang Jang, Kyung-Hwa Park, Jong Hee Shin, Sook In Jung
BACKGROUND: We investigated the clinical characteristics and risk factors for mortality in adults with persistent candidemia. METHODS: All patients ≥18 years old with candidemia in two Korean tertiary hospitals from 2007 to 2014 were investigated. Persistent candidemia was defined as isolation of the same Candida species ≥5 days after initiation of antifungal therapy. Non-persistent candidemia was defined as candidemia persisting for ≤3 days after initiation of antifungal therapy...
June 3, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28579302/direct-acting-antiviral-treatment-against-hepatitis-c-virus-infection-in-hiv-infected-patients-en-route-for-eradication
#9
Pierre Pradat, Pascal Pugliese, Isabelle Poizot-Martin, Marc-Antoine Valantin, Lise Cuzin, Jacques Reynes, Eric Billaud, Thomas Huleux, Firouze Bani-Sadr, David Rey, Anne Frésard, Christine Jacomet, Claudine Duvivier, Antoine Cheret, Laurent Hustache-Mathieu, Bruno Hoen, André Cabié, Laurent Cotte
OBJECTIVES: Direct-Acting Antivirals (DAAs) opened a new era in HCV treatment. We report the impact of HCV treatment in French HIV-HCV coinfected patients. METHODS: All HIV-HCV patients from the Dat'AIDS cohort followed between 2012 and 2015 were included. HCV status was defined yearly as naive, spontaneous cure, sustained virological response (SVR12), failure or reinfection. RESULTS: Among 32,945 HIV-infected patients, 15.2% were positive for anti-HCV antibodies...
June 2, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28579305/frequent-capsule-switching-in-ultra-virulent-meningococci-are-we%C3%A2-ready-for-a-serogroup-b-st-11-complex%C3%A2-outbreak
#10
Jay Lucidarme, Aiswarya Lekshmi, Sydel R Parikh, James E Bray, Dorothea M Hill, Holly B Bratcher, Steve J Gray, Anthony D Carr, Keith A Jolley, Jamie Findlow, Helen Campbell, Shamez N Ladhani, Mary E Ramsay, Martin C J Maiden, Ray Borrow
The meningococcal ST-11 complex (cc11) causes large invasive disease outbreaks with high case fatality rates, such as serogroup C (MenC) epidemics in industrialised nations in the 1990s and the serogroup W epidemic currently expanding globally. Glycoconjugate vaccines are available for serogroups A, C, W and Y. Broad coverage protein-based vaccines have recently been licensed against serogroup B meningococci (MenB), however, these do not afford universal MenB protection. Capsular switching from MenC to MenB among cc11 organisms is concerning because a large MenB cc11 (B:cc11) outbreak has the potential to cause significant morbidity and mortality...
June 1, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28579304/modelled-seasonal-influenza-mortality-shows-marked-differences-in-risk-by-age-sex-ethnicity-and-socioeconomic-position-in-new-zealand
#11
Trang Q T Khieu, Nevil Pierse, Lucy Frances Telfar-Barnard, Jane Zhang, Q Sue Huang, Michael G Baker
OBJECTIVES: Influenza is responsible for a large number of deaths which can only be estimated using modelling methods. Such methods have rarely been applied to describe the major socio-demographic characteristics of this disease burden. METHODS: We used quasi Poisson regression models with weekly counts of deaths and isolates of influenza A, B and respiratory syncytial virus for the period 1994 to 2008. RESULTS: The estimated average mortality rate was 13...
June 1, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28579303/first-report-of-candida-auris-in-oman-clinical-and-microbiological-description-of-five-candidemia-cases
#12
LETTER
Turkiya Al-Siyabi, Ibrahim Al Busaidi, Abdullah Balkhair, Zakariya Al-Muharrmi, Maya Al-Salti, Badriya Al'Adawi
No abstract text is available yet for this article.
June 1, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28579301/incidence-presentation-and-outcome-of%C3%A2-toxoplasmosis-in-hiv-infected-in-the-combination-antiretroviral-therapy-era
#13
Raquel Martin-Iguacel, Magnus Glindvad Ahlström, Madeleine Touma, Frederik Neess Engsig, Nina Breinholt Stærke, Mette Stærkind, Niels Obel, Line D Rasmussen
BACKGROUND: HIV-associated incidence and prognosis of cerebral toxoplasmosis (CTX) is not well established during later years. METHODS: From the Danish HIV Cohort Study, we identified 6325 HIV-infected individuals. We assessed incidence, mortality, predictive and prognostic factors of CTX during the pre-combination antiretroviral therapy (pre-cART; 1995-1996) and cART-era (1997-2014). Adjusted incidence rate ratios (aIRR), mortality rate ratios (aMRR) and 95% confidence intervals (CI) were assessed using Poisson regression analysis...
June 1, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28576596/bronchoalveolar-lavage-triacetylfusarinine-c-tafc-determination-for-diagnosis-of-invasive-pulmonary-aspergillosis-in-patients-with-hematological-malignancies
#14
LETTER
Thomas Orasch, Juergen Prattes, Klaus Faserl, Susanne Eigl, Wiebke Düttmann, Herbert Lindner, Hubertus Haas, Martin Hoenigl
No abstract text is available yet for this article.
May 31, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28552764/metalware-associated-orthopaedic-infections-caused-by-staphylococcus-lugdunensis-an-emerging-pathogen
#15
LETTER
Ang Li, Nicholas Gow, Bridget L Atkins, Adrian Taylor, Tim Peto, Martin A McNally, Philippa C Matthews
No abstract text is available yet for this article.
May 25, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28551371/an-evaluation-of-purified-salmonella-typhi-protein-antigens-for-the-serological-diagnosis-of-acute-typhoid-fever
#16
Nga Tran Vu Thieu, Tan Trinh Van, Anh Tran Tuan, Elizabeth J Klemm, Chau Nguyen Ngoc Minh, Phat Voong Vinh, Duy Pham Thanh, Thanh Ho Ngoc Dan, Trung Pham Duc, Pinky Langat, Laura B Martin, Jorge Galan, Li Liang, Philip L Felgner, D Huw Davies, Hanna K de Jong, Rapeephan R Maude, Masako Fukushima, Lalith Wijedoru, Aniruddha Ghose, Rasheda Samad, Arjen M Dondorp, Abul Faiz, Thomas C Darton, Andrew J Pollard, Guy E Thwaites, Gordon Dougan, Christopher M Parry, Stephen Baker
OBJECTIVES: The diagnosis of typhoid fever is a challenge. Aiming to develop a typhoid diagnostic we measured antibody responses against Salmonella Typhi (S. Typhi) protein antigens and the Vi polysaccharide in a cohort of Bangladeshi febrile patients. METHODS: IgM against 12 purified antigens and the Vi polysaccharide was measured by ELISA in plasma from patients with confirmed typhoid fever (n = 32), other confirmed infections (n = 17), and healthy controls (n = 40)...
May 25, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28551369/comparing-viral-load-metrics-and-evaluating-their-use-for-hiv-surveillance
#17
Renee Bolijn, Eline L M Op de Coul, Ard van Sighem, Willem L Blok, Mirjam E Kretzschmar, Janneke C M Heijne
OBJECTIVES: To investigate the value of in-care viral load (ICVL) and other viral load (VL) metrics for HIV surveillance by comparing time trends and associations with numbers of new HIV diagnoses. METHODS: Data from 20,740 HIV patients registered in the Dutch ATHENA-cohort between 2002 and 2013 were used. We compared: six ICVL metrics (i.e. mean of the mean/first/last/highest log VL, median of the median log VL, first log VL for newly diagnosed combined with mean log VL for all others), log VL at diagnosis, proportion of patients with transmission risk (>400 copies/ml) or suppressed VL (≤200 copies/ml)...
May 25, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28551372/clinical-course-and-perinatal-transmission-of-chronic-hepatitis-b-during-pregnancy-a-real-world-prospective-cohort-study
#18
Zhi-Xian Chen, Gui-Fang Gu, Zhao-Lian Bian, Wei-Hua Cai, Yi Shen, Yan-Li Hao, Sheng Zhang, Jian-Guo Shao, Gang Qin
OBJECTIVE: To determine the clinical course and perinatal transmission of chronic hepatitis B during pregnancy in a real life setting. METHODS: A total of 221 singleton pregnant women with detectable HBV-DNA levels (≥10(3) copies/mL) were enrolled during January 2011 to June 2015. Forty-three high viraemic patients (≥10(6) copies/mL) received telbivudine in the 2(nd) or 3(rd) trimester according to their intention, while 89 high viraemic and 79 low viraemic (≥10(3) and <10(6) copies/mL) patients were the control cohorts...
May 24, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28551370/multiple-introductions-and-onward-transmission-of-hiv-1-subtype-b-strains-in-shanghai-china
#19
Xiaoshan Li, Kexin Zhu, Yile Xue, Feiran Wei, Rong Gao, Ralf Duerr, Kun Fang, Wei Li, Yue Song, Guoping Du, Wenjuan Yan, Taha Hussein Musa, You Ge, Yu Ji, Ping Zhong, Pingmin Wei
OBJECTIVE: To investigate the viral genetic evolution, spatial origins and patterns of transmission of HIV-1 subtype B in Shanghai, China. METHODS: A total of 242 Shanghai subtype B and 1519 reference pol sequences were subjected to phylogenetic inference and genetic transmission network analyses. RESULTS: Phylogenetic analyses revealed that subtype B strains circulating in Shanghai were genetically diverse and closely associated with viral sequence lineages in Beijing (76 of 242 [31...
May 24, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28551368/hhv-6-reactivation-as-a-cause-of-fever-in%C3%A2-autologous-hematopoietic-stem-cell-transplant-recipients
#20
M A Colombier, S Amorim, M Salmona, C Thieblemont, J Legoff, M Lafaurie
OBJECTIVES: We report the biological and clinical impacts possibly associated with HHV-6 reactivation in autologous hematopoietic stem cell transplant (AHSCT) recipients after intensive chemotherapy regimen for lymphoma. METHODS: We retrospectively reviewed clinical, biological, radiological, treatment and outcomes of patients with positive HHV-6 DNA in whole blood following autologous hematopoietic stem cell transplantation. RESULTS: Blood HHV-6 reactivation was reported in 27 (8...
May 24, 2017: Journal of Infection
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